Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(127 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(90 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6170 produits trouvés pour "Apoptose"
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DMH2
CAS :DMH2 is an antagonist of bone morphogenetic protein (BMP) type I receptor. It acts by decreasing growth and inducing cell death of lung cancer cell lines.Formule :C27H25N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :451.52Anticancer agent 72
CAS :Compound 8c inhibits K+ channel and induces apoptosis, showing promise as an anticancer agent.Formule :C20H19N7O2Couleur et forme :SolidMasse moléculaire :389.41Mcl1-IN-3
CAS :Mcl1-IN-3 is an Mcl1 inhibitor. It has an IC50 and Ki of 0.67 and 0.13 μM, respectively.Formule :C27H22ClN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :487.93NSC114792
CAS :NSC114792 is a selective JAK3 inhibitor.Formule :C26H32N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.62PQ1 Succinate
CAS :PQ1 Succinate boosts GJIC and connexin in breast cancer cells without impacting normal mammary cells.Formule :C25H28F3N3O6Couleur et forme :SolidMasse moléculaire :523.5EGFR-IN-51
CAS :EGFR-IN-51 effectively inhibits EGFR and mutations with IC50s of 0.493-461.63 μM; it induces apoptosis in cancer cells.Formule :C21H15N3O2SCouleur et forme :SolidMasse moléculaire :373.43Darinaparsin
CAS :Darinaparsin, a dimethylated arsenic-glutathione compound, is cytotoxic to various cancer cells with diverse IC50 values and inhibits tumor growth in mice.Formule :C12H22AsN3O6SCouleur et forme :SolidMasse moléculaire :411.31CMC2.24
CAS :CMC2.24 inhibits Ras and ERK1/2, fights pancreatic tumors in mice, blocks MMPs (IC50: 2-69 µM), and reduces osteoarthritis by stabilizing cartilage.Formule :C26H21NO5Couleur et forme :SolidMasse moléculaire :427.45AP23464
CAS :AP23464 inhibits Src/Abl kinases, effective on imatinib-resistant CML cells (IC50=14nM), blocks cell cycle, induces apoptosis, not against T315I mutant.Formule :C26H30N5O2PDegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :475.52HDAC-IN-51
HDAC-IN-51 is an HDAC inhibitor.Formule :C27H24N4O2Degré de pureté :98.85%Couleur et forme :SolidMasse moléculaire :436.51GL-V9
CAS :GL-V9 is an AMPK activator, protecting against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy.Formule :C24H27NO5Couleur et forme :SolidMasse moléculaire :409.47pan-HER-IN-2
CAS :pan-HER-IN-2 (Compound C6) is an orally active, reversible, broad-spectrum HER inhibitor that acts on EGFR (IC50: 0.72 nM), HER4 (IC50: 2.0 nM), EGFRT790M (IC50Formule :C19H15BrClN5OCouleur et forme :SolidMasse moléculaire :444.71BLM-IN-1
CAS :BLM-IN-1: BLM inhibitor, KD 1.81 μM, IC50 0.95 μM; causes DNA damage, apoptosis, stops cancer cell growth.Formule :C28H35FN4OCouleur et forme :SolidMasse moléculaire :462.6HX 630
CAS :RXR agonistFormule :C28H27NO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :441.58Lexibulin dihydrochloride
CAS :Lexibulin 2HCl inhibits tubulin polymerization (IC50: 10-100 nM) and shows potent anti-cancer cytotoxicity and vascular disruption in vitro/vivo.Formule :C24H32Cl2N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :507.46WJ35435
CAS :WJ35435 is a histone deacetylase and topoisomerase I dual inhibitor.Formule :C20H21N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :351.4BEPP monohydrochloride
CAS :BEPP monohydrochloride is a double-strand RNA-dependent protein kinase (PKR) activator.Formule :C23H24ClN3O2Couleur et forme :SolidMasse moléculaire :409.91Tubulin inhibitor 30
CAS :Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.Formule :C22H19N3O5Couleur et forme :SolidMasse moléculaire :405.4Nevanimibe
CAS :Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).Formule :C27H39N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.62Ceranib-2
CAS :Ceranib-2, a ceramidase inhibitor (IC50: 28 μM, SKOV3), reduces sphingosine/S1P and promotes apoptosis, showing anticancer properties.
Formule :C25H19NO3Degré de pureté :98.49%Couleur et forme :SolidMasse moléculaire :381.42APX2009
CAS :APX2009, a 2nd-gen APE1/Ref-1 inhibitor, curbs NFkB activity, survivin, and prostate cancer cell growth; induces cell cycle arrest.Formule :C21H25NO4Couleur et forme :SolidMasse moléculaire :355.43Antitumor agent-81
CAS :Antitumor agent-81, a P62-RNF168 agonist, reduces H2A ubiquitination, hinders DNA repair, and inhibits tumor growth.Formule :C19H19N7O3Couleur et forme :SolidMasse moléculaire :393.4EC359
CAS :EC359 is a Leukemia Inhibitory Factor Receptor (LIFR) inhibitor with anticancer activity for the study of leukemia and endometrial cancer.Formule :C36H38F2O2Degré de pureté :98.11% - 98.11%Couleur et forme :SolidMasse moléculaire :540.68Simmiparib
CAS :Simmiparib (SMOCL-9112) is a PARP1 and PARP2 inhibitor that promotes apoptosis.Simmiparib is used to study Parkinson's disease and melanoma.Formule :C23H18F4N6O2Degré de pureté :99.05% - 99.51%Couleur et forme :SolidMasse moléculaire :486.42PARP1-IN-10
CAS :PARP1-IN-10 (12c) is a potent, non-toxic PARP1 inhibitor with a 50.62 nM IC50, enhancing TMZ effects and causing G2/M arrest and apoptosis.Formule :C20H23N3O5Couleur et forme :SolidMasse moléculaire :385.41PBOX-15
CAS :PBOX-15 induces apoptosis, regulates death receptors, enhances TRAIL effects, and inhibits T cell migration in myeloma cells.Formule :C28H19NO3Couleur et forme :SolidMasse moléculaire :417.46PD-1/PD-L1-IN-25
CAS :"PD-1/PD-L1-IN-25 blocks PD-1/PD-L1 (IC50: 16.17 nM), boosting T-cell anti-tumor immunity, useful for cancer research."Formule :C26H24ClN3O5Couleur et forme :SolidMasse moléculaire :493.94SMU127
CAS :SMU127 is an agonist of the toll-like receptor 1/2 (TLR1/2) heterodimer.Formule :C16H23N3O3SCouleur et forme :SolidMasse moléculaire :337.442-chloro Palmitic Acid
CAS :2-chloro Palmitic acid triggers NETosis, elevates COX-2, adhesion molecules in HCAECs, and induces apoptosis and caspase-3 in THP-1 cells/monocytes.Formule :C16H31ClO2Couleur et forme :SolidMasse moléculaire :290.87Trehalose 6-behenate
CAS :Trehalose 6-behenate is a Th1/Th17 skewing vaccine adjuvant.Formule :C34H64O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :664.86BP-1-108
CAS :BP-1-108 is a potent and selective STAT5 inhibitor.Formule :C32H38N2O6SCouleur et forme :SolidMasse moléculaire :578.72HMBPP triammonium
CAS :HMBPP triammonium is a stimulator of gamma delta T cells.Formule :C5H15NO8P2Couleur et forme :SolidMasse moléculaire :279.122Antitumor agent-19
CAS :Antitumor agent-19 is a modulator of tumor-associated macrophages with EC50s of 17.18 μM and 18.87 μM in the RAW 264.7 cells and the BMDM cells.Formule :C24H21ClF3N5ODegré de pureté :98.95% - 99.38%Couleur et forme :SolidMasse moléculaire :487.9Ref: TM-T10341
1mg109,00€2mg163,00€5mg241,00€1mL*10mM (DMSO)289,00€10mg354,00€25mg532,00€50mg745,00€100mg1.018,00€500mg2.035,00€YH-306
CAS :YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.Formule :C19H18N2O2Degré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :306.36LQZ-7F
CAS :LQZ-7F is a survivin dimerization inhibitor with anticancer activity.LQZ-7F induces proteasome-dependent survivin degradation and inhibits human tumor growth.Formule :C14H7N9O3Degré de pureté :98.64%Couleur et forme :SolidMasse moléculaire :349.26CP 461
CAS :CP 461 is a PDE2A inhibitor that promotes apoptosis in cancer cells without affecting normal cells or COX-1/2.Formule :C25H22ClFN2ODegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :420.91NSC49652
CAS :NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.Formule :C14H11NO2Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :225.24Ref: TM-T28206
1mg34,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg113,00€25mg222,00€50mg353,00€100mg530,00€500mg1.153,00€Ro 08-2750
CAS :Ro 08-2750: A non-peptide NGF inhibitor binding NGF (~1 µM IC50) & selectively inhibits p75NTR over TRKA and MSI RNA-binding (2.7 µM IC50).Formule :C13H10N4O3Degré de pureté :98.795%Couleur et forme :SolidMasse moléculaire :270.24Triciribine phosphate
CAS :Triciribine phosphate (VD 002) is an AKT inhibitor that inhibits neovascularization and can be used in the study of leukemia.Formule :C13H17N6O7PDegré de pureté :97.94%Couleur et forme :SolidMasse moléculaire :400.28MBM-55
CAS :MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM.Formule :C28H27FN6O2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :498.55Ref: TM-T11960
1mg168,00€5mg281,00€1mL*10mM (DMSO)309,00€10mg409,00€25mg627,00€50mg822,00€100mg1.108,00€500mg2.242,00€Ro 90-7501
CAS :Ro 90-7501, an amyloid β42 (Aβ42) protofibril and TPR-dependent PP5 inhibitor, is a novel cervical cancer cell radiosensitizer that inhibits HCMV.Formule :C20H16N6Degré de pureté :97.21% - 99.72%Couleur et forme :SolidMasse moléculaire :340.38Tubulin inhibitor 11
CAS :Potent, oral Tubulin inhibitor 11 hinders polymerization, targets Colchicine site, induces mitotic block, and apoptosis.Formule :C22H23N3O3SDegré de pureté :99.93%Couleur et forme :SoildMasse moléculaire :409.5Ref: TM-T67935
1mg35,00€5mg80,00€1mL*10mM (DMSO)96,00€10mg116,00€25mg259,00€50mg383,00€100mg545,00€200mg740,00€AMG PERK 44
CAS :AMG PERK 44 is a PERK inhibitor that induces autophagy.AMG PERK 44 inhibits GCN2 and B-Raf and can be used in cancer research.Formule :C34H29ClN4O2Degré de pureté :98.8% - 99.81%Couleur et forme :SolidMasse moléculaire :561.07GSK2593074A
CAS :GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.Formule :C27H23N5OSDegré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :465.57Ref: TM-T11484
1mg108,00€5mg260,00€1mL*10mM (DMSO)286,00€10mg409,00€25mg687,00€50mg964,00€100mg1.288,00€Pyrazoloacridine
CAS :Pyrazoloacridine (PD 115934) binds DNA, inhibits topo I/II, has 1.25 μM IC50 in K562 cells, and exhibits anti-cancer effects.Formule :C19H21N5O3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :367.4Minodronic acid
CAS :Minodronic acid (YM-529) is a P2X2/3 antagonist with anticancer properties, inhibiting cell growth and metastasis, and used in osteoporosis research.Formule :C9H12N2O7P2Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :322.15SCFSkp2-IN-2
CAS :SCFSkp2-IN-2, a Skp2 inhibitor, exhibits a dissociation constant (K_D) of 28.77 μM.
Formule :C17H20N4O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :312.37Tubulin inhibitor 32
CAS :Tubulin inhibitor 32 is a microtubule inhibitor with antiproliferative and antitumor activity that induces apoptosis and cell cycle arrest in the G2/M phase.Formule :C18H19N3O3Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :325.36Tanimilast
CAS :Tanimilast (CHF-6001) is a potent PDE4 inhibitor with IC50 of 0.026 nM, used topically for obstructive lung disease.Formule :C30H30Cl2F2N2O8SDegré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :687.54Perphenazine dihydrochloride
CAS :Perphenazine dihydrochloride: Oral dopamine, histamine-1 antagonist; targets D2, D3, 5-HT2A, Alpha-1A; may treat psychiatric disorders, cancer.Formule :C21H28Cl3N3OSDegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :476.89SLMP53-1
CAS :SLMP53-1 is a p53 activator with anti-tumor activity, activates reprogramming of glucose metabolism, and interferes with angiogenesis and migrationFormule :C20H18N2O2Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :318.37Ref: TM-T60839
1mL*10mM (DMSO)34,00€1mg119,00€5mg281,00€10mg462,00€25mg888,00€50mg1.485,00€100mg2.385,00€Exisulind
CAS :Exisulind (CP248) triggers apoptosis via PKG activation, shows antitumor effects, and inhibits growth in various rodent cancer models.Formule :C20H17FO4SDegré de pureté :97.94%Couleur et forme :SolidMasse moléculaire :372.41LDCA
CAS :LDCA inhibits LDH-A, disrupts mitochondrial function, induces apoptosis in cancer cells, and is non-toxic.Formule :C8H5Cl3FNODegré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :256.49UC-112
CAS :UC-112 is a novel potent IAP inhibitor and potently inhibits cell growth in two human melanoma and two human prostate cancer cell lines (IC50=0.7-3.4 uM).Formule :C22H24N2O2Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :348.44Ref: TM-T17195
500mgÀ demander1mg34,00€2mg44,00€5mg70,00€1mL*10mM (DMSO)78,00€10mg99,00€25mg202,00€50mg311,00€100mg445,00€STAT3-IN-13
CAS :STAT3-IN-13 is a STAT3 inhibitor with antiproliferative activity that induces apoptosis and can be used to study breast and liver cancer.Formule :C21H20N6O3SDegré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :436.49Cipepofol
CAS :HSK3486 is similar to propofol and is a general anesthetic, which may have therapeutic potential in insomnia, migraine, anxiety, analgesia, and other aspects.Formule :C14H20ODegré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :204.31Ref: TM-T32105
1mg58,00€5mg149,00€1mL*10mM (DMSO)150,00€10mg225,00€25mg444,00€50mg657,00€100mg1.044,00€200mg1.414,00€Cot inhibitor-1
CAS :Cot inhibitor-1 selectively blocks Tpl2 kinase, reducing TNF-alpha in blood (IC50: 5.7 nM). It may treat arthritis, IBD, and certain cancers.Formule :C27H27Cl2FN8Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :553.46Ref: TM-T10865
1mg73,00€5mg152,00€1mL*10mM (DMSO)177,00€10mg222,00€25mg401,00€50mg602,00€100mg887,00€200mg1.215,00€GSK2983559 free acid
CAS :GSK2983559 free acid selectively inhibits RIP2, reducing inflammatory cytokines in human bowel disease.Formule :C21H23N4O7PS2Degré de pureté :97.8700% - 99.56%Couleur et forme :SolidMasse moléculaire :538.53CCT018159
CAS :CCT018159: ATP-competitive HSP90 inhibitor, IC50 3.2 μM (human), 6.6 μM (yeast), blocks invasion, angiogenesis, induces G1 arrest and apoptosis.
Formule :C20H20N2O4Degré de pureté :98.78% - 99.79%Couleur et forme :SolidMasse moléculaire :352.38F16
CAS :F16 ((E)-4-(3-indolylvinyl)-N-methylpyridinium iodide) inhibits the growth of neu-overexpressing cells and the proliferation of mammary epithelial.Formule :C16H15IN2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :362.21HS-276
CAS :HS-276, a selective oral TAK1 inhibitor (Ki: 2.5 nM), also targets CLK2, GCK, ULK2, MAP4K5; potential for RA research.Formule :C24H29N5O2Degré de pureté :97.67% - 98.81%Couleur et forme :SolidMasse moléculaire :419.52Ref: TM-T62209
1mg63,00€5mg137,00€1mL*10mM (DMSO)161,00€10mg207,00€25mg408,00€50mg655,00€100mg1.009,00€200mg1.359,00€SB 699551 dihydrochloride
CAS :SB 699551 dihydrochloride is a 5-ht5a receptor antagonist.Formule :C34H47Cl2N3ODegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :584.66Ref: TM-T23325
1mg50,00€5mg105,00€1mL*10mM (DMSO)142,00€10mg170,00€25mg295,00€50mg424,00€100mg583,00€TAI-1
CAS :TAI-1 is a potent and specific Hec1 inhibitor, which disrupts Hec1-Nek2 protein interaction.Formule :C24H21N3O3SDegré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :431.51Ro24-7429
CAS :Ro24-7429: oral HIV-1 Tat antagonist, RUNX1 inhibitor with anti-HIV, antifibrotic, and anti-inflammatory properties.Formule :C14H13ClN4Degré de pureté :99.29% - 99.85%Couleur et forme :SolidMasse moléculaire :272.73Ref: TM-T28578
1mg87,00€5mg177,00€1mL*10mM (DMSO)203,00€10mg281,00€25mg480,00€50mg692,00€100mg973,00€500mg2.725,00€KR-33493
CAS :KR-33493 is a FAS-associated factor 1 (FAF1) inhibitor and can be used in studies about Parkinson's disease.Formule :C20H18BrN3O3SDegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :460.34GSK854
CAS :GSK854 is a selective TNNI3K inhibitor reducing heart damage and stress post-infarction in mice.Formule :C18H19ClN6O4S2Degré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :482.96Ref: TM-T24115
1mg92,00€5mg222,00€1mL*10mM (DMSO)245,00€10mg358,00€25mg710,00€50mg1.063,00€100mg1.684,00€500mg3.375,00€Mepazine
CAS :Mepazine, a MALT1 inhibitor, blocks GSTMALT1 (IC50: 0.83μM) and GSTMALT1 325-760 (IC50: 0.42μM), promoting apoptosis and reducing cell viability.Formule :C19H22N2SDegré de pureté :99.88% - 99.92%Couleur et forme :SolidMasse moléculaire :310.46Ref: TM-T16040
500mgÀ demander1mL*10mM (DMSO)35,00€10mg39,00€25mg60,00€50mg93,00€100mg116,00€200mg177,00€BCL6-IN-7
CAS :BCL6-IN-7 (BCL6 inhibitor-7) is a BCL6 corepressor-interaction inhibitor with potential antitumor activity, used in lymphoma research.Formule :C18H15ClN6ODegré de pureté :99.03%Couleur et forme :SolidMasse moléculaire :366.8Mitazalimab
CAS :Mitazalimab (ADC-1013/JNJ-64457107) is a CD40 agonist that stimulates T cells to attack tumors and remodels the tumor microenvironment.Degré de pureté :95.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 95.1% (SDS-PAGE); 98.7% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :143.42 kDaAnticancer agent 110
CAS :Anticancer Agent 110 exhibits potent in vitro anti-leukemia activity, demonstrating high cytotoxicity against K-562 lineage chronic myelogenous leukemia cellsFormule :C18H13FN6OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :380.4CCT020312
CAS :CCT020312 (0-9 µM, 24 h) treatment of medium HT29 cells for 24 h resulted in a concentration-dependent loss of P-S608-pRB.Cost-effective and quality-assured.Formule :C31H30Br2N4O2Degré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :650.4Ref: TM-T14902
1mg58,00€5mg133,00€1mL*10mM (DMSO)178,00€10mg227,00€25mg386,00€50mg572,00€100mg795,00€500mg1.648,00€LCS3
CAS :LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3Formule :C11H7ClN2O4Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :266.64NM-3
CAS :NM-3, an oral anti-angiogenic and anti-tumor agent, modulates radiation and blocks VEGF to curb endothelial growth and induce apoptosis.Formule :C13H12O6Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :264.23Ref: TM-T33701
1mg172,00€1mL*10mM (DMSO)394,00€5mg432,00€10mg618,00€25mg973,00€50mg1.333,00€100mg1.791,00€500mg3.529,00€eIF4A3-IN-1
CAS :eIF4A3-IN-1 is an inhibitor of eukaryotic initiation factor 4A3 (eIF4A3). eIF4A3-IN-1 inhibits cytosolic nonsense-mediated RNA decay at high concentrations.
Formule :C29H23BrClN5O2Degré de pureté :99.49% - 99.89%Couleur et forme :SolidMasse moléculaire :588.88JY-2
CAS :JY-2 is a forkhead transcription factor O1 (FoxO1) inhibitor with antidiabetic activity that inhibits FoxO1 transcription and can be used to study psoriasis.Formule :C13H7Cl2N3ODegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :292.12R306465
CAS :R306465 (JNJ-16241199) is an HDAC 1 inhibitor with broad-spectrum anti-tumor activity, inducing apoptosis, and can be used to study solid tumors.Formule :C19H19N5O4SDegré de pureté :98.46% - 99.54%Couleur et forme :SolidMasse moléculaire :413.45Vamotinib
CAS :Vamotinib (PF-114) is a tyrosine kinase inhibitor with antiproliferative and antitumor activity.Vamotinib is used in the study of Alzheimer's disease.Formule :C29H27F3N6ODegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :532.56Ref: TM-T63746
1mg101,00€5mg245,00€1mL*10mM (DMSO)288,00€10mg401,00€25mg717,00€50mg982,00€100mg1.341,00€200mg1.783,00€Lanperisone HCl
CAS :Lanperisone (NK433) is a potent, long-lasting muscle relaxant that inhibits spinal reflexes via noradrenergic system suppression.Formule :C15H19ClF3NODegré de pureté :98.67% - >99.99%Couleur et forme :SolidMasse moléculaire :321.77A09-003
CAS :A09-003 Inhibits the proliferation of leukemia cell lines and inhibits the increase of leukemia sequence-1 protein in HI bone marrow cells.Formule :C23H26N4ODegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :374.48Trk-IN-9
CAS :Trk-IN-9 is a TRK inhibitor with anticancer and antiproliferative activity and can be used in cancer research.Formule :C23H24ClFN6ODegré de pureté :98.15%Couleur et forme :SolidMasse moléculaire :454.93BCP-T.A
CAS :BCP-T.A is an iron death inducer that acts by binding to GPX4.Formule :C23H19Cl2N3OSDegré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :456.39MMRi64
CAS :MMRi64 inhibits Mdm2-MdmX, boosts p53, triggers apoptosis, and is used in cancer research.Formule :C22H17Cl2N3ODegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :410.3GSK-3β inhibitor 3
CAS :GSK-3β inhibitor 3 is a covalent inhibitor (IC50: 6.6 μM) of glycogen synthase kinase 3β (GSK-3β) that is potent, selective, and irreversible.GSK-3β inhibitor 3Formule :C18H14FNO2SDegré de pureté :97.53%Couleur et forme :SolidMasse moléculaire :327.37Ref: TM-T35554
1mg52,00€5mg111,00€1mL*10mM (DMSO)127,00€10mg166,00€25mg301,00€50mg452,00€100mg665,00€HBDDE
CAS :HBDDE inhibits PKCα/γ (IC50: 43/50 μM), favors them over PKCδ/βI/βII, and induces neuronal apoptosis. Derived from ellagic acid.Formule :C16H18O8Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :338.31TC-DAPK 6
CAS :TC-DAPK 6 is an ATP-competitive inhibitor of Death-associated protein kinase (DAPK) with IC50s of 69 and 225 nM for DAPK1 and DAPK3.Formule :C17H12N2O2Degré de pureté :98.73%Couleur et forme :SolidMasse moléculaire :276.29DB1976
CAS :DB1976: Selenophene DB270 analog, inhibits PU.1 (IC50=10 nM), disrupts PU.1/DNA (KD=12 nM), induces apoptosis, cell-permeable.Formule :C20H16N8SeDegré de pureté :98.74%Couleur et forme :SolidMasse moléculaire :447.35Stemazole
CAS :Stemazole activates human stem cell growth, boosts survival, reduces cell death, and aids myelin repair, with therapeutic potential in demyelinating diseases.Formule :C9H9N5OS2Degré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :267.33Ref: TM-T28866
1mg52,00€1mL*10mM (DMSO)95,00€5mg101,00€10mg164,00€25mg334,00€50mg532,00€100mg858,00€200mg1.149,00€Ciglitazone
CAS :Ciglitazone: potent PPARγ agonist, EC50 3 μM, oral hypoglycemic; reduces insulin, blood pressure, Th17 cells, VEGF; halts gastric cancer growth.Formule :C18H23NO3SDegré de pureté :98.23% - 99.84%Couleur et forme :White Cyrstalline SolidMasse moléculaire :333.45RO-5963
CAS :RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively).Formule :C24H21ClF2N4O5Degré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :518.9Ref: TM-T16771
1mg66,00€5mg187,00€1mL*10mM (DMSO)212,00€10mg269,00€25mg411,00€50mg532,00€100mg740,00€200mg982,00€CSN5i-3
CAS :CSN5i-3 is a potent, selective, and orally available inhibitor of the proteolytic subunit of the CSN complex, CSN5, as an anticancer agent.Cost-effective and quality-assured.Formule :C28H29F2N5O2Degré de pureté :99.56% - >99.99%Couleur et forme :SolidMasse moléculaire :505.56Ref: TM-T10895
1mg340,00€5mg732,00€1mL*10mM (DMSO)797,00€10mg1.108,00€25mg1.648,00€50mg2.223,00€100mg2.997,00€SPD304 dihydrochloride
CAS :SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.
Formule :C32H34Cl2F3N3O2Degré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :620.53W146
CAS :W146 is an S1PR1 antagonist that induces a significant but transient decrease in blood lymphocytes in mice.Formule :C16H27N2O4PDegré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :342.37ZDLD20
CAS :ZDLD20 is a CDK4 inhibitor with anti-HCT116 and anticancer activity that inhibits colony formation and blocks the G1 phase of the cell cycle.Formule :C22H22N6ODegré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :386.45Erastin2
CAS :Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.
Formule :C36H35ClN4O4Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :623.14p53-MDM2-IN-1
CAS :p53-MDM2-IN-1 (Example 30), an inhibitor targeting the p53-MDM2/X protein interaction, exhibits a K i value of 23.35 µM.Formule :C23H20ClN3O3Degré de pureté :99.98%Couleur et forme :SoildMasse moléculaire :421.88Necrostatin-5
CAS :Necrostatin-5 (Nec-5) inhibits RIP1 kinase, prevents cell necrosis, and protects Fadd-deficient Jurkat cells with an EC50 of 240 nM.Formule :C19H17N3O2S2Degré de pureté :99.40%Couleur et forme :SolidMasse moléculaire :383.49CTA 056
CAS :CTA 056 is an ITK inhibitor that inhibits the growth of MOLT-4 xenograft tumors in mice and can be used to study autoimmune disorders.Formule :C35H34N6ODegré de pureté :97.22% - 97.76%Couleur et forme :SolidMasse moléculaire :554.68HS38
CAS :HS38: DAPK-specific ATP-competitive inhibitor; Kds: DAPK1 (300 nM), PIM3 (200 nM), ZIPK (280 nM); useful in smooth muscle disorder research.Formule :C14H12ClN5O2SDegré de pureté :98.19%Couleur et forme :SolidMasse moléculaire :349.8AOH1160
CAS :AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA).Formule :C25H20N2O3Degré de pureté :98.46% - 99.52%Couleur et forme :SolidMasse moléculaire :396.44PARP/PI3K-IN-1
CAS :PARP/PI3K-IN-1 is a PARP and PI3K dual inhibitor with anticancer and antiproliferative activities for the study of breast, pancreatic and lung cancers.Formule :C33H28F4N8O3Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :660.62
