Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(127 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(90 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6170 produits trouvés pour "Apoptose"
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Cu(II)-Elesclomol
CAS :Cu(II)-Elesclomol is a complex formed by the anticancer agent Elesclomol and Cu(II), which has anticancer activity and can be used in the study of leukemia.Formule :C19H18CuN4O2S2Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :462.05BI-0252
CAS :BI-0252 is an inhibitor of MDM2-p53 (IC50:4 nM).Formule :C30H26Cl2FN3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :566.45Ac-YVAD-pNA
CAS :Ac-YVAD-pNA, a specific substrate for Caspase-1, serves to detect Caspase-1 activity, a crucial mediator of inflammatory processes [1] [2].Formule :C29H36N6O10Couleur et forme :SolidMasse moléculaire :628.63915-Deoxy-Δ12,14-prostaglandin A1
CAS :15-Deoxy-Δ12,14-Prostaglandin A1, a deoxyanalog of prostaglandins, inhibits NF-κB signaling and induces apoptosis. It also prevents TNF-α-induced upregulation of inflammatory endothelial cell adhesion molecules (CAM) and reduces monocyte arrest [1].Formule :C20H30O3Couleur et forme :SolidMasse moléculaire :318.457ZINC00784494
CAS :ZINC00784494 is a selective inhibitor of LCN2 (lipocalin-2), which inhibits cancer cell proliferation and reduces p-AKT , and promotes apoptosis. IBC.Formule :C20H14N2O3SDegré de pureté :98.90%Couleur et forme :SolidMasse moléculaire :362.4(S)-Verapamil hydrochloride
CAS :(S)-Verapamil hydrochloride is an inhibitor of leukotriene C4 (LTC4) and calcein transport by MRP1,and leads to the death of potentially resistant tumor cells.Formule :C27H39ClN2O4Couleur et forme :SolidMasse moléculaire :491.06Estrogen receptor modulator 10
CAS :Compound G-5b, an estrogen receptor modulator 10, functions as an estrogen receptor (ER) antagonist (IC50=6.7 nM) and degrader (DC50=0.4 nM).Formule :C32H37F9N4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :728.71AM-8735
CAS :AM-8735 is an inhibitor of MDM2 ( IC50: 25 nM).Formule :C27H31Cl2NO6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :568.51Pelcitoclax
CAS :Pelcitoclax (APG-1252) is a powerful inhibitor of the Bcl-2 and Bcl-xl proteins, displaying significant antineoplastic and pro-apoptotic properties[1].Formule :C57H66ClF4N6O11PS4Couleur et forme :SolidMasse moléculaire :1281.84GSK840
CAS :GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds the RIP3 kinase domain (IC50: 0.9 nM), and inhibits kinaseFormule :C21H23N3O3Degré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :365.43Atiprimod dihydrochloride
CAS :JAK2 inhibitor; IC50=397 nM; hampers STAT3/5 phosphorylation; curbs growth and triggers apoptosis in JAK2V617F+ cells.Formule :C22H46Cl2N2Couleur et forme :SolidMasse moléculaire :409.52SD 1008
CAS :SD 1008 is a JAK2/STAT3 signaling pathway inhibitor. SD 1008 inhibits activation of STAT3, JAK2, and Src.Formule :C18H19NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.35Famitinib malate
CAS :Famitinib malate (SHR1020) is a potent oral kinase inhibitor targeting c-kit, VEGFR-2, and PDGFRβ, with IC50s 2.3, 4.7, 6.6 nM, useful for cancer research.Formule :C27H33FN4O7Couleur et forme :SolidMasse moléculaire :544.57RMC-4998
CAS :RMC-4998 is an orally available KRASG12C mutant inhibitor that targets the active or GTP-bound state of the KRASG12C mutant,inhibit ERK and apoptosis.Formule :C57H74N8O7Degré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :983.25Ref: TM-T79870
1mg89,00€5mg187,00€10mg274,00€25mg464,00€50mg803,00€100mg1.388,00€200mg1.872,00€1mL*10mM (DMSO)298,00€HDAC/JAK/BRD4-IN-1
CAS :HDAC/JAK/BRD4-IN-1 (compound 25ap) is a potent triple inhibitor targeting HDAC, JAK, and BRD4.Formule :C24H28N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :448.52BPR1J-340
CAS :BPR1J-340, a novel potent FLT3 inhibitor, shows anticancer promise, with IC50 ~25 nM and GC50 ~5 nM, causing apoptosis in AML cells.Formule :C29H34N8O3Couleur et forme :SolidMasse moléculaire :542.63ERα antagonist 1
CAS :ERα antagonist 1 is a selective, potent, covalent estrogen receptor alpha (ERα) antagonist that blocks the cell cycle of MCF-7 cells in G0/G1 phase and inducesFormule :C33H32N2O5SCouleur et forme :SolidMasse moléculaire :568.68INCB3619
CAS :INCB3619 is a selective and potent inhibitor of ADAM with antitumour effects, inhibiting ADAM10, ADAM17, MMP12 and MMP15.Formule :C22H27N3O5Degré de pureté :98.41% - 99.51%Couleur et forme :SolidMasse moléculaire :413.47PD-L1-IN-2
CAS :PD-L1-IN-2, a Naamidine J derivative, serves as a promising antineoplastic immunomodulator by hindering PD-L1 activity.Formule :C33H38N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :586.68APE1-IN-2
CAS :APE1-IN-2 (AP1), a Pt(IV) proagent, targets APE1 protein, induces DNA damage, and triggers apoptosis with anticancer effects.Formule :C9H12Cl2N4O5PtDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :522.21HJC0152 free base
CAS :HJC0152 (free base) is an orally active, potent STAT3 inhibitor that impedes cell cycle progression, induces apoptosis, and notably reduces MDA-MB-231 xenograftFormule :C15H13Cl2N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :370.19NSC194598
CAS :NSC194598 is a p53 DNA-binding inhibitor, demonstrating an in vitro IC50 of 180 nM and an in vivo range of 2-40 μM.Formule :C20H19N3OCouleur et forme :SolidMasse moléculaire :317.38Ethylene dimethanesulfonate
CAS :Ethylene dimethanesulfonate has selective pro-apoptotic effects on LCs. Ethylene dimethanesulfonate is a mild alkylating, non-volatile methanesulfonic diesterFormule :C4H10O6S2Degré de pureté :98.94%Couleur et forme :SolidMasse moléculaire :218.25Bcl-2-IN-11
CAS :Bcl-2-IN-11 (compound 6) is a potent and selective inhibitor of Bcl-2 activity, exhibiting an IC50 of 0.9 nM, and demonstrates minimal inhibition against Bcl-xlFormule :C45H49ClFN7O8SCouleur et forme :SolidMasse moléculaire :902.43MTI-31
CAS :MTI-31 (LXI-15029) is a potent oral mTORC1/2 inhibitor with a Kd of 0.20 nM, >5,000-fold selectivity, and an IC50 of 39 nM.Formule :C26H30N6O3Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :474.55CHM-1
CAS :CHM-1 is an inducer of apoptosis, and displays potent antitumor ability in human hepatocellular carcinoma by activation of Cdc2 kinase activity.Formule :C16H10FNO3Degré de pureté :99.839%Couleur et forme :SolidMasse moléculaire :283.25HDAC-IN-53
CAS :HDAC-IN-53 inhibits HDAC1-3 with IC50s: 47, 125, 450 nM. Inactive on class II HDACs; triggers apoptosis; reduces tumor growth in mice.Formule :C23H20ClN7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :461.9hGGPPS-IN-3
CAS :13h (hGGPPS-IN-3), a strong C2-ThP-BPs hGGPPS blocker, triggers MM cell apoptosis and shows in vivo anti-myeloma effects.Formule :C21H19BrN4O7P2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :613.31M190S
CAS :M109S is a novel small molecule that shields cells from mitochondria-dependent apoptosis, demonstrating effectiveness both in vitro and in vivo.Formule :C21H21N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :375.42Antitumor agent-92
CAS :Antitumor Agent-92, a derivative of Icaritin, halts cell cycle, triggers cell death, and is promising for liver cancer study.Formule :C33H41NO10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :611.68Ogremorphin
CAS :Ogremorphin (GPR68-IN-1) is a potent inhibitor of GPR68, exhibiting an EC50 of 170 nM.it is utilized in the study of autoimmune chronic inflammatory diseases [1Formule :C21H17N3OSDegré de pureté :99.65% - 99.65%Couleur et forme :SolidMasse moléculaire :359.44PD-1/PD-L1-IN-33
CAS :PD-1/PD-L1-IN-33 (Compound N11), a PD-1/PD-L1 inhibitor, effectively impedes the interaction between PD-1 and PD-L1 with an IC50 of 6.3 nM.Formule :C26H27N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :425.53Agerafenib hydrochloride
CAS :Agerafenib hydrochloride is a highly potent inhibitor of BRAFV600E (Kd: 14 nM).Formule :C24H23ClF3N5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :553.92RIP1 kinase inhibitor 8
CAS :RIP1 Kinase Inhibitor 8 (Compound 77), a potent and highly selective dihydropyrazole (DHP) RIP1 kinase inhibitor, exhibits an IC50 of 20 nM and effectivelyFormule :C18H19F2N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :375.37C6 Phytoceramide (t18:0/6:0)
CAS :C6 Phytoceramide (t18:0/6:0) is a lipid molecule that can be used in life science related research. The CAS number of C6 Phytoceramide (t18:0/6:0) is 249728-94-7.Formule :C24H49NO4Couleur et forme :SolidMasse moléculaire :415.659ASC-69
CAS :ASC-69 (APY69) is a promising potent inhibitor of the PD-1/PD-L1 signaling pathway, classified as a small-molecule compound [1].Formule :C19H19N7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :345.4Z-YVAD-CMK
CAS :Z-YVAD-CMK is an inhibitor of both caspase-1 and caspase-3, as referenced in [1].Formule :C30H37ClN4O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :633.09Tylvalosin
CAS :Tylvalosin (Acetylisovaleryltylosin) is a broad-spectrum macrolide antibiotic with antibacterial and antiviral properties, effective against PRRSV infection.Formule :C53H87NO19Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1042.25DX3-235
CAS :DX3-235 is an oxidative phosphorylation (OXPHOS) inhibitor on mitochondrial complex I function in galactose-containing media, resulting in reduced ATP.Formule :C26H39N5O6S2Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :581.75MY-673
CAS :MY-673, a colchicine binding site inhibitor (CBSI), impedes tubulin polymerization and disrupts the ERK signaling pathway, consequently modulating SMAD4 proteinFormule :C18H14N2O4Couleur et forme :SolidMasse moléculaire :322.31RET-IN-17
CAS :RET-IN-17 inhibits RET kinase; may help in IBS pain and RET-activated cancers.Formule :C27H28F4N4O4Couleur et forme :SolidMasse moléculaire :548.53Thaspine acetate
CAS :Thaspine: inhibits topoisomerase IB, reduces VEGF, stops endothelial cell growth via PI3K/MAPK pathways.Formule :C22H23NO8Couleur et forme :SolidMasse moléculaire :429.425RUNX-IN-2
CAS :RUNX-IN-2 (Compound Conjugate 3) covalently attaches to RUNX-binding sequences, preventing RUNX proteins from associating with their targets, thereby inhibitingFormule :C71H88Cl2N24O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1524.52Topoisomerase II inhibitor 15
CAS :Topoisomerase II inhibitor 15 (compound 2g) serves as a potent apoptotic inducer, exhibiting heightened selectivity for head and neck tumors [1].Formule :C15H11Cl2N5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :332.19Vepafestinib
CAS :Vepafestinib is a RET inhibitor with potential antineoplastic activity[1].Formule :C26H30N6O3Degré de pureté :98.56%Couleur et forme :SolidMasse moléculaire :474.55FGFR-IN-8
CAS :FGFR-IN-8, potent oral FGFR inhibitor for wild-type/mutant types, induces apoptosis with anti-cancer properties.Formule :C27H31Cl2N9O2Couleur et forme :SolidMasse moléculaire :584.5Eeyarestatin I
CAS :Eeyarestatin I blocks ER protein degradation, hinders p97/atx3 processes, and induces anticancer proteins.Formule :C27H25Cl2N7O7Degré de pureté :98% - 98.99%Couleur et forme :SolidMasse moléculaire :630.44SCH79797 dihydrochloride
CAS :SCH79797 dihydrochloride is a PAR1 antagonist with IC50 70 nM, Ki 35 nM, antiproliferative, and pro-apoptotic properties.Formule :C23H27Cl2N5Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :444.4WNY1613
CAS :WNY1613: Potent PI3Kδ inhibitor with anti-NHL properties, induces apoptosis in cells, affects phosphorylation in vitro/in vivo.Formule :C29H35N9O3Couleur et forme :SolidMasse moléculaire :557.65MRT199665
CAS :MRT199665, a selective MARK/SIK/AMPK inhibitor, blocks SIK CRTC3 S370 phosphorylation and triggers apoptosis in AML cells.Formule :C28H31N5O2Couleur et forme :SolidMasse moléculaire :469.58TNIK-IN-6
CAS :TNIK-IN-6 (Compound 9) acts as an inhibitor of Traf2 and Nck-interacting kinase (TNIK), exhibiting an inhibitory concentration (IC50) of 0.93 μM, a kinaseFormule :C13H8BrFN4Couleur et forme :SolidMasse moléculaire :319.13Sirt1/2-IN-3
CAS :Sirt1/2-IN-3 (compound PS9) serves as a dual inhibitor of SIRT1/2, exhibiting IC50 values of 1.4 μM (SIRT1) and 2.0 μM (SIRT2), respectively.Formule :C17H14ClNO4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :363.82Antitumor agent-60
CAS :Antitumor agent-60 inhibits growth by targeting RAS-RAF, binding CRAF (Kd: 721.3 nM), boosting p53/ROS, causing apoptosis, and arresting G2/M phase.Formule :C24H28O10SCouleur et forme :SolidMasse moléculaire :508.54Lepadin E
CAS :Lepadin E, a notably cytotoxic compound, effectively stimulates ferroptosis via the canonical p53-SLC7A11-GPX4 pathway.Formule :C26H47NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.66MK-2206 free base
CAS :MK-2206 free base is an allosteric Akt inhibitor that is both potent and selective, administered orally, exhibiting IC50 values of 8, 12, and 65 nM for Akt1,Formule :C25H21N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :407.47Biguanidinium-porphyrin
CAS :Imidodicarbonimidic diamide hydrochloride, a phototoxic compound with anti-proliferative properties.Formule :C46H36ClN9Degré de pureté :92.48% - 93.91%Couleur et forme :SoildMasse moléculaire :750.29AAPK-25
CAS :AAPK-25, a dual Aurora/PLK inhibitor, disrupts mitosis, induces apoptosis, and has antitumor properties.Formule :C21H13Cl2N3O2SDegré de pureté :97.05%Couleur et forme :SolidMasse moléculaire :442.32Ref: TM-T10215
1mg54,00€5mg118,00€10mg172,00€25mg313,00€50mg469,00€100mg680,00€1mL*10mM (DMSO)131,00€BCL6-IN-4
CAS :BCL6-IN-4, a potent inhibitor of B-cell lymphoma 6 (BCL6), exhibits anti-tumor activities with an inhibitory concentration 50 (IC50) value of 97 nM[1].Formule :C25H35ClN6O3Couleur et forme :SolidMasse moléculaire :503.04Lacutoclax
CAS :Lacutoclax (LP-108) is an orally active and selective Bcl-2 inhibitor with antitumor activity both in vivo and ex vivo，lymphoma and leukemia.Formule :C48H55ClN8O7SCouleur et forme :SolidMasse moléculaire :923.52Nedometinib
CAS :Nedometinib (NFX-179) is a MEK1 inhibitor with anticancer and antitumor activities, which can be used to study malignant tumors.Formule :C17H16FIN4O3Degré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :470.24Ref: TM-T78209
1mg66,00€5mg145,00€10mg215,00€25mg353,00€50mg537,00€100mg708,00€1mL*10mM (DMSO)150,00€CNDAC
CAS :CNDAC, a nucleoside analog, is a major metabolite of oral drug sapacitabine.Formule :C10H12N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :252.23Docebenone
CAS :Docebenone is a selective and orally active inhibitor of 5-LO.Formule :C21H26O3Couleur et forme :SolidMasse moléculaire :326.43WEHI-345
CAS :WEHI-345 is a potent and selective RIPK2 inhibitor which shows NOD signalling events yet prevents inflammatory cytokine production.Formule :C22H23N7ODegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :401.46S-Adenosyl-L-methionine (1,4-butanedisulfonate)
CAS :S-Adenosyl-L-methionine (SAMe) 1,4-butanedisulfonate functions as an orally active methyl group donor and serves as a dietary supplement known for itsFormule :C19H32N6O11S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :616.69YS-363
CAS :YS-363 is a potent, selective, and orally active inhibitor of the epidermal growth factor receptor (EGFR), exhibiting half-maximal inhibitory concentrations (Formule :C30H30N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :494.58MS-177
CAS :MS-177 is a PROTAC EZH2 degrader that promotes cholangiocarcinoma growth through the EZH2-mediated WNT7B/β-catenin pathway.Formule :C48H55N11O8Couleur et forme :SolidMasse moléculaire :914.02Ref: TM-T69771
1mg84,00€5mg177,00€10mg281,00€25mg557,00€50mg893,00€100mg1.341,00€1mL*10mM (DMSO)358,00€NLRP3 agonist 1
CAS :Vatalanib hydrochloride (PTK787 hydrochloride) is a VEGF inhibitor that reduces the number and area of Aβ plaques in the cortex of 5xFAD mice.Formule :C15H16N6Degré de pureté :99.01%Couleur et forme :SolidMasse moléculaire :280.33CPT-Se3
CAS :CPT-Se3, a camptothecin derivative, boosts anticancer activity, triggers apoptosis in Hep G2, and is cytotoxic to various cells with IC50 of 2.19-4.7 μM.Formule :C24H20N2O6Se2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :590.35HM90822
CAS :HM90822 is an IAP antagonist that inhibits XIAP and cIAP1/2 protein expression, induces IAP ubiquitination and promotes proteasome-dependent IAP degradation.Formule :C30H36ClF2N7O4Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :632.1ICL-CCIC-0019
CAS :ICL-CCIC-0019 inhibits ChoKα, causes G1 arrest, ER stress, and cancer cell apoptosis.Formule :C26H44Br2N4Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :572.46Ref: TM-T27579
2mg43,00€5mg70,00€10mg92,00€25mg132,00€50mg200,00€100mg344,00€200mg505,00€1mL*10mM (DMSO)88,00€HDAC-IN-60
CAS :HDAC-IN-60 (compound 21a), a potent histone deacetylase (HDAC) inhibitor, promotes intracellular reactive oxygen species (ROS) production, induces DNA damage,Formule :C20H26N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :390.43AR420626
CAS :AR420626: selective FA3R agonist, guards against SALS, effects blocked by BHB, a FA3R antagonist.Formule :C21H18Cl2N2O3Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :417.29CR-1-31-B
CAS :CR-1-31-B, a synthetic rocaglate, inhibits eIF4A, hinders protein synthesis initiation, and induces apoptosis in cancer cells.Formule :C28H29NO8Couleur et forme :SolidMasse moléculaire :507.539RET-IN-25
CAS :RET-IN-25 (compound 6b) is an anticancer RET kinase inhibitor that demonstrates efficacy against medullary thyroid carcinoma (MTC), exhibiting half-maximalFormule :C22H17N3O5SCouleur et forme :SolidMasse moléculaire :435.45ER proteostasis regulator-1
CAS :ER Proteostasis Regulator-1 (Compound 481) is a potent modulator of endoplasmic reticulum proteostasis with research applications in Alzheimer's disease andFormule :C18H22N2O3Couleur et forme :SolidMasse moléculaire :314.38MI-219
CAS :MI-219 is a human double minute 2 (HDM2) inhibitor.Formule :C27H32Cl2FN3O4Couleur et forme :SolidMasse moléculaire :552.47SF5
CAS :SF5 is an inhibitor of the apoptosis pathway through JNK-p53-caspase apoptotic cascade.Formule :C15H13NSDegré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :239.34SW IV-52
CAS :SW IV-52 is an XIAP-inhibitor that acts as a second mitochondria-derived activator of caspases (SMAC) mimetic.Formule :C25H39ClN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :479.05PDK4-IN-1 hydrochloride
CAS :PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4, IC50 value = 84 nM).Formule :C22H20ClN3O2Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :393.87Ref: TM-T12412L
1mg70,00€5mg150,00€10mg215,00€25mg358,00€50mg515,00€100mg707,00€200mg1.009,00€1mL*10mM (DMSO)165,00€SWS1
CAS :SWS1, a d-(+)-biotin-conjugated PD-L1 inhibitor (IC50: 1.8 nM), displays anticancer activity by augmenting tumor-infiltrating lymphocytes and demonstrating antiFormule :C47H53ClN6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :849.48ST1074
CAS :ST1074, a dual inhibitor of CerS2 and CerS4, promotes apoptosis and is applicable in cancer research [1].Formule :C20H36ClNO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :373.96CP-24879 hydrochloride
CAS :CP-24879 HCl, a Δ5D/Δ6D dual-inhibitor, reduces liver lipid buildup and inflammation.
Formule :C11H18ClNODegré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :215.72BHD
CAS :BHD, a reversible male contraceptive agent, effectively induces spermatogenic cell apoptosis and causes abnormalities in seminiferous tubules in vivo at dosesFormule :C21H16Cl2N4OCouleur et forme :SolidMasse moléculaire :411.28Mcl-1 inhibitor 17
CAS :Mcl-1 Inhibitor 17 is a compound that functions as an inhibitor of the Mcl-1 protein, specifically designed for use in cancer and other disease research [1].Formule :C27H25FN4O2Couleur et forme :SolidMasse moléculaire :456.51NHWD-870
CAS :NHWD-870 selectively inhibits BET bromodomains BRD2-4, BRDT; potent anti-cancer effect by inducing apoptosis, halting cell growth.Formule :C29H29N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :491.59Colletofragarone A2
CAS :Colletofragarone A2 from Colletotrichum sp. blocks mutant p53 and HSP90, aiding cancer treatment.Formule :C22H26O6Couleur et forme :SolidMasse moléculaire :386.44SM-433
CAS :SM-433: Smac mimetic, blocks IAPs, strong XIAP BIR3 affinity (IC50 <1 μM). See patent WO2008128171A2.Formule :C32H43N5O4Couleur et forme :SolidMasse moléculaire :561.71GSK-2245035 maleate
CAS :GSK-2245035 maleate is a selective Toll-like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties.Formule :C24H38N6O6Couleur et forme :SolidMasse moléculaire :506.6YM281
CAS :YM281 is a potent EZH2 inhibitor, causes apoptosis and G0/G1 arrest, has antitumor activity in vivo, and may be researched for lymphoma.Formule :C56H71N7O9SCouleur et forme :SolidMasse moléculaire :1018.27HSP90/mTOR-IN-1
"HSP90/mTOR-IN-1 is a dual Hsp90/mTOR inhibitor (IC50: 69/29 nM), halting SW780 cell growth and inducing apoptosis/autophagy in cancer research."Formule :C36H34ClFN6O5SCouleur et forme :SolidMasse moléculaire :717.21Bcl-2-IN-13
CAS :Bcl-2-IN-13 is a potent inhibitor of Bcl-2, exhibiting an IC50 of 17 nM, and holds potential for use in cancer research [1].Formule :C42H44ClN7O6S3Couleur et forme :SolidMasse moléculaire :874.49Mcl-1 inhibitor 13
CAS :Mcl-1 Inhibitor 13 (Example 9), with a Ki of 8.2 nM, serves as an MCL-1 inhibitor suitable for cancer research [1].Formule :C47H45ClFN7O6Couleur et forme :SolidMasse moléculaire :858.35AGN194204
CAS :AGN194204 (IRX4204), an oral RXR agonist, inactive against RAR, has Kd 0.4-3.8 nM & EC50 0.08-0.8 nM, with anti-inflammatory and anticarcinogenic properties.Formule :C24H32O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :352.51MAO-B-IN-26
CAS :MAO-B-IN-26 (Compound IC9) serves as both a MAO-B and acetylcholinesterase inhibitor.Formule :C17H12BrNODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :326.19Necrocide 1
CAS :Necrocide 1 is a inducer of cancer cell necrosis that is not inhibited by caspase, BCL2 , or TNFα, and acts through the mitochondrial regulatory pathway.Formule :C23H27NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :365.47WF-210
CAS :WF-210 is an effective activator of procaspase-3 that acts by inducing apoptosis in cancer cells and reducing tumor growth.Formule :C41H38FN7O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :791.85SM-1295
CAS :SM-1295: IAP antagonist, Kd 3077 nM XIAP-BIR3, 3.2 nM c-IAP1-BIR3, 9.5 nM c-IAP2-BIR3.Formule :C29H36BrN5O4Couleur et forme :SolidMasse moléculaire :598.53C 87
CAS :C 87: Small-molecule TNF-α inhibitor, binds TNFα, inhibits cytotoxicity with IC50 of 8.73 μM, blocks signaling.Formule :C24H15ClN6O3SDegré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :502.93HS148
CAS :HS148 selectively inhibits DAPK3 (Ki 119 nM), reducing gastric cancer progression via ULK1-dependent autophagy and tumor suppression pathways.Formule :C15H14FN5O2SDegré de pureté :98.024%Couleur et forme :SolidMasse moléculaire :347.37INU-152
CAS :INU-152: pan-RAF inhibitor with potent anti-tumor effects on BRAFV600E cancers, inhibits MAPK in mutant cells, minimal side effects on RAS-mutant melanoma.Formule :C20H13F2N7O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :469.42
