Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5592 produits trouvés pour "Apoptose"
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Antitumor agent-112
<p>Antitumor agent-112 (compound 3a) is a potent antitumor agent that induces apoptosis and exhibits cytotoxic activity on A549 cells, with an IC50 value of 91.35</p>Formule :C18H17ClN4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :388.87Bcl-xL antagonist 2
CAS :<p>Bcl-xL antagonist 2 is an effective and selective antagonist of Bcl-xL with an IC50 of 91 nM and a Ki of 65 nM.</p>Formule :C21H16N4O3S2Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :436.51Ferroptosis-IN-14
<p>Ferroptosis-IN-14 (compund 36) exhibits the most potent anti-ferroptotic activity with an EC50 value of 0.58 ± 0.02 μM, demonstrating excellent anti-ferroptotic efficacy, as well as stability in microsomes and plasma.</p>Couleur et forme :Odour SolidSCR7
CAS :<p>SCR7, a specific DNA Ligase IV inhibitor, blocks nonhomologous end-joining (NHEJ).</p>Formule :C18H14N4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :334.4Vonlerolizumab
CAS :<p>Vonlerolizumab (MOXR 0916) is a humanized IgG OX40 agonist monoclonal antibody with potential in cancer and immune disease research.</p>Degré de pureté :SDS-PAGE:97.3%;SEC-HPLC:99.4%Couleur et forme :LiquidMasse moléculaire :145.25 kDaNDI-Lyso
CAS :<p>NDI-Lyso is an anticancer agent targeting lysosomes, functioning through an enzyme-induced self-assembly (EISA) mechanism catalyzed by Cathepsin B. In cancer cell lysosomes, it forms rigid long fibers, promoting lysosomal swelling, lysosomal membrane permeabilization (LMP), and membrane disruption. This leads to non-classical caspase-independent apoptosis (Apoptosis). NDI-Lyso demonstrates significant selective anticancer activity across various cancer cell lines and drug-resistant cancer cells (IC50 approximately 10 μM), while exhibiting low toxicity to normal cells (IC50 > 60 μM).</p>Formule :C71H100N22O13Couleur et forme :SolidMasse moléculaire :1469.69PROTAC HIF-1α degrader-1
<p>PROTAC HIF-1α degrader-1 (compound V2) is an effective proteolysis-targeting chimeric (PROTAC) degrader of hypoxia-inducible factor-1α (HIF-1α), with an IC50 value of 7.54 µM. This compound exhibits anti-proliferative activity, reduces HIF-1α protein expression, and induces apoptosis.</p>Formule :C51H72N6O7SCouleur et forme :SolidMasse moléculaire :913.22CQ-Mito
<p>CQ-Mito, a derivative of CQ, demonstrates excellent phototherapeutic efficacy with a PI value of 167. This compound induces cell death through mechanisms such as apoptosis and ferroptosis. It mediates mitochondrial dysfunction, characterized by alterations in mitochondrial morphology and loss of MMP. Additionally, CQ-Mito effectively inhibits tumor growth in 3D multicellular tumor spheroid models.</p>Formule :C45H42BrN6O4PCouleur et forme :SolidMasse moléculaire :841.73Streptonigrin
CAS :<p>Streptonigrin, from Streptomyces flocculus, has anti-tumor and anti-bacterial properties, inhibiting PAD1-4.</p>Formule :C25H22N4O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.46(E/Z)-10-Hydroxy-2-decenoic acid
CAS :<p>(E/Z)-10-Hydroxy-2-decenoic acid is a useful organic compound for research related to life sciences.</p>Formule :C10H18O3Couleur et forme :SolidMasse moléculaire :186.251RET-IN-28
CAS :<p>RET-IN-28 (Compound 16) is an inhibitor of RET (a transmembrane receptor tyrosine kinase). It specifically inhibits the activity of a mutant RET enzyme (RET-V804M) and is utilized in cancer research.</p>Formule :C26H29N9Couleur et forme :SolidMasse moléculaire :467.57Ceftiofur hydrochloride
CAS :<p>Ceftiofur hydrochloride (U-67279A) is a stable, broad-spectrum 3rd-gen cephalosporin with antibacterial properties.</p>Formule :C19H17N5O7S3·HClDegré de pureté :99.51%Couleur et forme :Off-White SolidMasse moléculaire :560.02Albicanol
CAS :<p>Albicanol is a biochemical.</p>Formule :C15H26OCouleur et forme :SolidMasse moléculaire :222.372EJMC-1
CAS :<p>EJMC-1 is an inhibitor of TNF-α with an IC50 value of 42 μM and can be used in studies about auto-inflammatory diseases.</p>Formule :C17H11ClN2O4SDegré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :374.8MG-C-30
CAS :<p>MG-C-30 is an orally active CD27 agonist with an EC50 of 0.84 μM. It activates co-stimulatory signaling in NK cells and T cells, thereby enhancing the immune response. In the EG7-OVA mouse model, MG-C-30 demonstrates antitumor activity.</p>Formule :C24H26N4O3SCouleur et forme :SolidMasse moléculaire :450.55AKN-028
CAS :<p>AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = 6 nM). AKN-028 causes dose-dependent inhibition of FLT3 autophosphorylation.</p>Formule :C17H14N6Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :302.33Silicon naphthalocyanine dichloride
CAS :<p>Silicon naphthalocyanine dichloride is a photosensitizer with potential anti-tumor activity. This compound is employed in photodynamic therapy to inhibit cancer by effectively absorbing specific wavelengths of light, thereby generating oxygen radicals that aid in the destruction of cancer cells. The biocompatibility of Silicon naphthalocyanine dichloride demonstrates promising prospects for medical applications.</p>Formule :C48H24Cl2N8SiCouleur et forme :SolidMasse moléculaire :811.75Sodium propionate
CAS :<p>Sodium propionate (Propionic acid sodium salt) has potential anti-inflammatory and anti-apoptotic activities, inhibiting certain signaling pathways.</p>Formule :C3H5NaO2Couleur et forme :SoildMasse moléculaire :96.06PCC0208017
CAS :<p>PCC0208017 is an inhibitor of MARK3 and MARK4 with IC50s of 1.8 and 2.01 nM. PCC0208017 disrupts microtubule dynamics and displays potent antitumor activity.</p>Formule :C19H20F3N7Degré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :403.4Phosphocreatine dipotassium
CAS :<p>Phosphocreatine dipotassium, primarily found in the skeletal muscles of vertebrates and one of organic compounds known as alpha amino acids and derivatives.</p>Formule :C4H8K2N3O5PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :287.29
