Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5600 produits trouvés pour "Apoptose"
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c-JUN peptide
CAS :<p>Peptide from c-Jun (33-57) blocks JNK binding, inhibits phosphorylation, upregulates p21, and induces HeLa cell apoptosis.</p>Formule :C121H210N36O34SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2743.55Thalidomide-NH-C6-NH2
CAS :<p>Thalidomide-NH-C6-NH2 is a synthetic conjugate compound designed as an E3 ligase ligand-linker.</p>Formule :C19H24N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :372.42hCAIX/XII-IN-13
<p>hCAIX/XII-IN-13 functions as an inhibitor targeting specific human carbonic anhydrases (hCA) IX and XII, crucial in tumor-related processes. Demonstrating efficacy, this compound offers inhibitory K i values of 0.08 µM for IX and 0.06 µM for XII. Additionally, under hypoxic conditions, hCAIX/XII-IN-13 enhances the effectiveness of Doxorubicin on MCF-7 cells by promoting G2/M phase cell cycle arrest and increasing apoptosis.</p>Formule :C25H16N6O6SCouleur et forme :SolidMasse moléculaire :528.5PROTAC HDAC6 degrader 1
CAS :<p>Compound A6, a potent PROTAC HDAC6 degrader, has a DC50 of 3.5 nM and induces apoptosis in myeloid leukemia cells.</p>Formule :C37H46N6O10Couleur et forme :SolidMasse moléculaire :734.827-O-(tert-Butyldimethylsilyl)withaferin A
CAS :<p>Compound 9a, a withanolide, induces apoptosis and has anti-cancer properties.</p>Formule :C34H52O6SiCouleur et forme :SolidMasse moléculaire :584.86NCT-58
CAS :<p>NCT-58 is a potent HSP90 inhibitor that blocks Akt, downregulates HER family, and induces apoptosis in HER2+ breast cancer without triggering HSR.</p>Formule :C27H34N2O5Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :466.57CDC20-IN-2
<p>CDC20-IN-2 (14c) is an inhibitor of Cdc20 with a KD of 7.65 μM, inducing G2/M phase arrest, promoting DNA damage accumulation, and stabilizing key substrates such as Cyclin B1 and Bim. This leads to enhanced apoptosis, as well as inhibition of tumor cell proliferation and migration.</p>Couleur et forme :Odour SolidTRP-601
CAS :<p>TRP-601 is a caspase inhibitor.</p>Formule :C40H48F2N6O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :826.852Albanol B
CAS :<p>Albanol B, from mulberries, combats Alzheimer's, bacteria, and oxidation, hinders cancer growth, and triggers cell arrest and apoptosis.</p>Formule :C34H22O8Couleur et forme :SolidMasse moléculaire :558.53RMC-9805
CAS :<p>RMC-9805(Zoldonrasib) is a KRAS G12D inhibitor with anti-tumor and anti-proliferative activity for the study of pancreatic cancer.</p>Formule :C63H88F3N11O7Degré de pureté :98.10% - 99.51%Couleur et forme :SolidMasse moléculaire :1168.44BRD4 Inhibitor-39
<p>BRD4 Inhibitor-39 (compound 12m) is an orally active inhibitor of BRD4 with an IC50 of 0.02 μM. It can induce apoptosis and demonstrates antitumor activity.</p>Formule :C24H19BrFN9Couleur et forme :SolidMasse moléculaire :532.37DJ4
CAS :<p>DJ4 induces a dose-dependent pro-apoptotic effect in the micromolar range.</p>Formule :C19H16N4OSDegré de pureté :≥98%Couleur et forme :SoildMasse moléculaire :348.42LSD1-IN-26
<p>LSD1-IN-26 (12u) is a potent LSD1 inhibitor (IC50=25.3 nM), also inhibits MAO-A/B, induces apoptosis in MGC-803, for gastric cancer research.</p>Formule :C27H25Cl2F2N3OCouleur et forme :SolidMasse moléculaire :516.41HX009
<p>HX009 is a bispecific antibody that targets PD1 and CD47, though its binding to CD47 is attenuated. HX009 functions by blocking PD1/CD47 and can be utilized in research related to non-Hodgkin lymphoma (NHL).</p>Couleur et forme :Odour LiquidCh282-5
CAS :<p>Ch282-5, an orally active inhibitor targeting the Bcl-2 protein, promotes mitochondria-dependent apoptosis (Apoptosis) by disrupting mitophagy and the mTOR pathway. It demonstrates antiproliferative effects on colorectal cancer cells, effective both in vitro and in vivo, while also inhibiting metastasis. Further, Ch282-5 augments Oxaliplatin-induced autophagy (Autophagy) by downregulating Mcl-1 protein and raising platelet count, which helps mitigate the adverse effects of Navitoclax.</p>Formule :C34H34N2Na2O14S2Couleur et forme :SolidMasse moléculaire :804.75Dimethachlor
CAS :<p>Dimethachlor is a pesticide and herbicide used in wetland areas.</p>Formule :C13H18ClNO2Couleur et forme :SolidMasse moléculaire :255.74CDK8-IN-13
CAS :<p>CDK8-IN-13 is a CDK8 inhibitor (IC50: 51.9 nM) with potent, selective and oral activity.</p>Formule :C14H11N3ODegré de pureté :99.28%Couleur et forme :SoildMasse moléculaire :237.26Z-Asp-CH2-DCB
CAS :<p>Z-Asp-CH2-DCB is an irreversible inhibitor of broad spectrum caspase.</p>Formule :C20H17Cl2NO7Degré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :454.26Apoptosis inducer 26
<p>Apoptosisinducer 26 (compound [AgCl(dap2SH)(PPh3)2]) is a mononuclear Ag(I) ligand-based autophagy inducer that exhibits antibacterial and anticancer activities against various bacterial strains and cancer cell lines. This compound facilitates the accumulation of Ag(I) ions in the periphery of bacteria, effectively inhibiting the growth of both Gram-positive (+) and Gram-negative (-) bacteria. Additionally, Apoptosisinducer 26 can intercalate between the base pairs of CT DNA, inducing apoptosis in A549 cells. It also possesses radical scavenging properties, which helps prevent oxidative stress.</p>Formule :C40H36AgClN4P2SCouleur et forme :SolidMasse moléculaire :810.07WK499
<p>BCL6-IN-10 (Compound WK499) is an inhibitor of BCL6, disrupting its interaction with the SMRT protein and promoting apoptosis, cell cycle arrest, and DNA damage</p>Formule :C21H20BrN7O3Couleur et forme :SolidMasse moléculaire :498.33
