Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5592 produits trouvés pour "Apoptose"
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HS-438
CAS :<p>HS-438 inhibits imatinib-resistant BCR-ABL T315I mutation in chronic myeloid leukemia.</p>Formule :C17H17N3O3SCouleur et forme :SolidMasse moléculaire :343.4Anticancer agent 76
CAS :<p>Compound CT2-3 is an anticancer agent that hinders growth, induces arrest, ROS, and apoptosis in NSCLC cells.</p>Formule :C32H33NO5SCouleur et forme :SolidMasse moléculaire :543.67ARN5187
CAS :<p>ARN5187, a lysosomal REV-ERB β ligand, inhibits transcription and autophagy, shows efficacy, cytotoxicity, and induces apoptosis.</p>Formule :C24H32FN3OCouleur et forme :SolidMasse moléculaire :397.53PD-1-IN-18
CAS :<p>PD-1-IN-18 is a PD1 inhibitor of signaling pathway, and acts as an immunomodulator.</p>Formule :C11H17N5O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :347.28ISC-4
CAS :<p>ISC-4 is an Akt inhibitor, which activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.</p>Formule :C11H13NSeCouleur et forme :SolidMasse moléculaire :238.19PD-1/PD-L1-IN-29
CAS :<p>PD-1/PD-L1-IN-29 (S4-1) is a potent inhibitor of the PD-1/PD-L1 interaction, with an IC50 value of 6.1 nM.</p>Formule :C26H24N2O6Couleur et forme :SolidMasse moléculaire :460.48MPT0B214
CAS :<p>MPT0B214, a potent microtubule inhibitor, disrupts tubulin polymerization and kills various cancer cells, including drug-resistant types.</p>Formule :C20H20N2O5Couleur et forme :SolidMasse moléculaire :368.38ACA-28
CAS :<p>ACA-28 is an ERK MAPK signalling modulator that induces apoptosis in melanoma cells by overexpressing ERK.</p>Formule :C17H16O6Degré de pureté :98.73%Couleur et forme :SolidMasse moléculaire :316.31CDK1/2/4-IN-1
CAS :<p>CDK1/2/4-IN-1 inhibits CDKs (IC50: CDK1-1.47μM; CDK2-0.78μM; CDK4-0.87μM) and is useful in cancer studies, affecting apoptosis and the cell cycle.</p>Formule :C15H16N2O2SCouleur et forme :SolidMasse moléculaire :288.36DRAK1/2-IN-1
CAS :<p>DRAK1/2-IN-1 is a potent inhibitor targeting both DRAK1 and DRAK2, displaying dissociation constants (Kd) of 1 µM and 6 µM, respectively.</p>Formule :C22H24N2O3SCouleur et forme :SolidMasse moléculaire :396.5YLT205
CAS :<p>YLT205 is an inducer of apoptosis in human colorectal cells that acts by inhibiting tumor growth.</p>Formule :C16H12BrClN4O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :471.78Anticancer agent 71
CAS :<p>Compound 4b, a potent anticancer, halts G2/M cell cycle, triggers apoptosis, alters Bax, Ikb-α, PARP, and Bcl-2 levels.</p>Formule :C18H13ClF3N5OCouleur et forme :SolidMasse moléculaire :407.78AMPK activator 11
CAS :<p>AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-</p>Formule :C25H20N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :408.45VEGFR-2-IN-23
CAS :<p>VEGFR-2-IN-23 (11b) is a potent VEGFR-2 inhibitor with an IC50 of 0.34 nM, exhibits antitumor effects, and causes G1 cell cycle arrest.</p>Formule :C22H15N5O2Couleur et forme :SolidMasse moléculaire :381.39CU-3
CAS :<p>CU-3 inhibits DGKalpha, reducing cancer growth and boosting anti-cancer immunity.</p>Formule :C16H12N2O4S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :392.47Ferroptosis inducer-1
CAS :<p>Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .</p>Formule :C25H21ClN2O5Couleur et forme :SolidMasse moléculaire :464.9Tubulin polymerization-IN-22
CAS :<p>Tubulin polymerization-IN-22 inhibits tubulin (IC50=8.1μM), blocks G2/M phase, and triggers apoptosis.</p>Formule :C19H16O4Couleur et forme :SolidMasse moléculaire :308.33NF-κB-IN-5
CAS :<p>NF-κB-IN-5 (compound 4d) is an orally active NF-κB inhibitor.</p>Formule :C23H27N3O4Couleur et forme :SolidMasse moléculaire :409.48Adapalene sodium salt
CAS :<p>Adapalene (CD 271; Differin) sodium salt is a synthetic retinoid and a Retinoic acid receptor agonist.</p>Formule :C28H28NaO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :435.519EGFR-IN-56
CAS :<p>EGFR-IN-56 (13a) inhibits EGFR, EGFRT790M (IC50: 541.7nM), EGFRT790M/L858R (IC50: 132.1nM), blocks G2/M phase, and triggers apoptosis.</p>Formule :C23H22N4O3SCouleur et forme :SolidMasse moléculaire :434.51LG308
CAS :<p>LG308, a synthetic compound, has anti-tumor properties, inducing apoptosis and mitotic arrest, thereby suppressing prostate cancer growth.</p>Formule :C19H17FN2OCouleur et forme :SolidMasse moléculaire :308.35PHA-680626
CAS :<p>PHA-680626 is a PLK inhibitor, effective on resistant leukemia cells, with IC50: Plk1 (0.53 μM), Plk2 (0.07 μM), Plk3 (1.61 μM).</p>Formule :C23H26N6O2SCouleur et forme :SolidMasse moléculaire :450.56Anti-inflammatory agent 47
CAS :<p>Flo8, an anti-inflammatory and antioxidant agent, effectively suppresses the release of reactive oxygen species (ROS) and nitric oxide (NO) while inhibiting</p>Formule :C25H18N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :394.42SZM-1209
CAS :<p>SZM-1209 is a potent and specific RIPK1 inhibitor with oral activity, displaying a dissociation constant (Kd) of 85 nM.</p>Formule :C31H29F5N4O5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :696.71GW837016X
CAS :<p>GW837016X, also known as NEU-391, is a potent inhibitor of protozoan parasite proliferation.</p>Formule :C25H20ClFN4OSCouleur et forme :SolidMasse moléculaire :478.97ENMD-1068 HCl
CAS :<p>ENMD-1068 HCl (ENMD 1068) is a PAR-2 antagonist. ENMD-1068 HCl inhibits the development of endometriosis in a mouse model.</p>Formule :C15H29N3O2Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :283.41PI3Kδ/γ-IN-3
CAS :<p>PI3Kδ/γ-IN-3 (Compound 58) is an orally active dual inhibitor of PI3Kδ (IC50: 1 nM) and PI3Kγ (IC50: 16 nM).</p>Formule :C23H20ClN9OCouleur et forme :SolidMasse moléculaire :473.92Anticancer agent 55
CAS :<p>Potent anticancer agent inhibits cell growth, migration, induces apoptosis; promising for prostate, breast cancer studies.</p>Formule :C28H21Br2FN2O2Couleur et forme :SolidMasse moléculaire :596.294NVX-207
CAS :<p>NVX-207 is a derivative of betulinic acid. It has anti-cancer activity.</p>Formule :C36H59NO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :601.86HI5
CAS :<p>HI5: potent tubulin/IDO inhibitor, IC50 70 nM (HeLa), blocks kynurenine, G2/M arrest, spurs T cell activity, & triggers apoptosis.</p>Formule :C42H43N5O8Couleur et forme :SolidMasse moléculaire :745.82Justicidin B
CAS :<p>Justicidin B: anticancer, proapoptotic, inhibits bone resorption & platelets, antiviral, fungicidal, antiprotozoal.</p>Formule :C21H16O6Couleur et forme :SolidMasse moléculaire :364.35Isodispar B
CAS :<p>Isodispar B: an anticancer drug, halts many cancer types' growth, triggers cell death.</p>Formule :C20H18O5Couleur et forme :SolidMasse moléculaire :338.35Nampt-IN-8
CAS :<p>Nampt-IN-8 is a NAMPT inhibitor (IC50: 0.183 μM) and a good substrate for NQO1. Nampt-IN-8 induces reactive oxygen species (ROS) production and apoptosis.</p>Formule :C36H35N3O4Couleur et forme :SolidMasse moléculaire :573.68Anticancer agent 58
<p>Anticancer agent 58 targets A549/T24 cell lines; IC50: 0.6/0.7 μM. It triggers apoptosis, ups Ca2+/ROS, and lowers mitochondrial potential.</p>Formule :C39H55NO5Couleur et forme :SolidMasse moléculaire :617.86pan-HER-IN-2
CAS :<p>pan-HER-IN-2 (Compound C6) is an orally active, reversible, broad-spectrum HER inhibitor that acts on EGFR (IC50: 0.72 nM), HER4 (IC50: 2.0 nM), EGFRT790M (IC50</p>Formule :C19H15BrClN5OCouleur et forme :SolidMasse moléculaire :444.71PI3K-IN-34
CAS :<p>PI3K-IN-34 targets PI3K-α/β/δ (IC50: 11.73/6.09/11.18 μM); potential leukemia research tool.</p>Formule :C23H22N6O3Couleur et forme :SolidMasse moléculaire :430.46GL-V9
CAS :<p>GL-V9 is an AMPK activator, protecting against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy.</p>Formule :C24H27NO5Couleur et forme :SolidMasse moléculaire :409.47JS-K
CAS :<p>JS-K is a Nitric oxide donor. It has antiproliferative activity.</p>Formule :C13H16N6O8Couleur et forme :SolidMasse moléculaire :384.3hGGPPS-IN-1
CAS :<p>HGGPPS-IN-1: analog of C2-ThP-BPs, inhibits hGGPPS, triggers apoptosis in MM cells, shows anti-myeloma effects in vivo.</p>Formule :C13H13N3O6P2SCouleur et forme :SolidMasse moléculaire :401.27IW-927
CAS :<p>IW-927 is a potent and selective TNFα/TNFRc1 interaction antagonist.</p>Formule :C22H23N3O3S2Couleur et forme :SolidMasse moléculaire :441.57LWG-301
<p>LWG-301, a GLS1 allosteric inhibitor, IC50 7 nM, impedes glutamine metabolism and prompts apoptosis; shows antitumor effects.</p>Formule :C28H38N8O3SCouleur et forme :SolidMasse moléculaire :566.72ARN5187 trihydrochloride
CAS :<p>ARN5187 trihydrochloride: a REV-ERBβ inhibitor that blocks transcription, autophagy, and induces apoptosis with lysosomal cytotoxicity.</p>Formule :C24H35Cl3FN3OCouleur et forme :SolidMasse moléculaire :506.912HDAC1/2 and CDK2-IN-1
CAS :<p>Compound 14d inhibits HDAC1 (IC50=70.7μM), HDAC2 (23.1μM), CDK2 (0.80μM), blocks cell cycle, induces apoptosis, and shows in vivo anti-tumor effects.</p>Formule :C26H22ClN7OCouleur et forme :SolidMasse moléculaire :483.95αβ-Tubulin-IN-1
CAS :<p>αβ-Tubulin-IN-1 is a potent and orally active inhibitor of αβ-Tubulin.</p>Formule :C25H19N3O3Couleur et forme :SolidMasse moléculaire :409.44ZMF-10
CAS :<p>ZMF-10 inhibits PAK1 (IC50: 174 nM), PAK2, PAK3; affects apoptosis, ER stress, migration in cancer studies.</p>Formule :C19H17F6N7OCouleur et forme :SolidMasse moléculaire :473.38MMP-9-IN-3
CAS :<p>MMP-9-IN-3: MMP-9/AKT inhibitor (IC50: 5.56/2.11 nM), forms H-bonds, cytotoxic, induces apoptosis, used in cancer research.</p>Formule :C29H25N3O4Couleur et forme :SolidMasse moléculaire :479.53Mps1-IN-5
CAS :<p>Mps1-IN-5: oral Mps1 inhibitor with 29 nM IC50, induces apoptosis, G2/M arrest, and has anti-tumor properties.</p>Formule :C24H25N9Couleur et forme :SolidMasse moléculaire :439.52GK563
CAS :<p>GK563, an iPLA2 inhibitor (IC50=1nM), is 22,000x more potent vs. cPLA2 and may reduce β-cell death in type 1 diabetes.</p>Formule :C16H22O2Couleur et forme :SolidMasse moléculaire :246.34TNF-α-IN-10
CAS :<p>TNF-α-IN-10 (compound 8a) acts as an inhibitor of IL-6 and TNF-α, demonstrating anti-inflammatory activity [1].</p>Formule :C17H14O4Couleur et forme :SolidMasse moléculaire :282.29S65487
CAS :<p>S65487 (VOB560) inhibits Bcl-2, including G101V and D103Y variants, while sparing MCL-1, BFL-1, and BCL-XL, supporting its anticancer potential.</p>Formule :C41H41ClN6O4Degré de pureté :99.034%Couleur et forme :SolidMasse moléculaire :717.26JMX0293
<p>JMX0293, a salicylamide derivative, inhibits STAT3, inducing MDA-MB-231 cell apoptosis with IC50=3.38μM, while sparing MCF-10A (IC50>60μM).</p>Formule :C25H30Cl2N4O7Couleur et forme :SolidMasse moléculaire :569.43Caspase-3/7 activator 2
<p>Caspase-3/7 activator 2 triggers apoptosis with tumor selectivity and anti-proliferative properties.</p>Formule :C32H34N2O7Couleur et forme :SolidMasse moléculaire :558.62Rohinitib
CAS :<p>Rohinitib, an eIF4A inhibitor, triggers apoptosis in AML cells and lessens tumor load in models.</p>Formule :C29H31NO8Couleur et forme :SolidMasse moléculaire :521.56SCAL-255
CAS :<p>SCAL-255 is a mitochondrial complex I (CI) inhibitor, exhibiting potent inhibition with an IC50 of 1.14 μM.</p>Formule :C27H28F3N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :527.54Nutlin-1
CAS :<p>Nutlin-1 is a p53-MDM2 binding inhibitor, p-Glycoprotein (p-gp) transport substrate, and antitumor agent.</p>Formule :C32H34Cl2N4O4Couleur et forme :SolidMasse moléculaire :609.54ANO1-IN-3
CAS :<p>ANO1-IN-3 (Compound 3n) can induces apoptosis that is a potent and selective inhibitor of ANO1 with an IC 50 of 1.23 μM [1].</p>Formule :C20H17NO3Couleur et forme :SolidMasse moléculaire :319.35CAY10503
CAS :<p>CAY10503: proapoptotic, anti-growth agent; arrests cell cycle at G0-G1; IC50 = 7-23 μM; induces HL60 differentiation in 72 hours.</p>Formule :C18H14O3Couleur et forme :SolidMasse moléculaire :278.3Anticancer agent 66
CAS :<p>Anticancer agent 66, a ciprofloxacin analog, triggers apoptosis in MCF-7 cells.</p>Formule :C26H23Cl2FN6O2S2Couleur et forme :SolidMasse moléculaire :605.53Flunisolide hemihydrate
CAS :<p>Flunisolide hemihydrate, a corticosteroid with anti-inflammatory properties, treats asthma and rhinitis by inducing eosinophil apoptosis.</p>Formule :C48H64F2O13Couleur et forme :SolidMasse moléculaire :887.024BIBU-1361 dihydrochloride
CAS :<p>BIBU-1361 dihydrochloride inhibits EGFR kinase, blocking MAPKK/MAPK activation.</p>Formule :C22H29Cl3FN7Couleur et forme :SolidMasse moléculaire :516.87Topoisomerase IIα-IN-3
CAS :<p>Topoisomerase IIα-IN-3 is a DNA-inserting topoisomerase-Iiα inhibitor that blocks the cell cycle in G0/G1 phase and induces apoptosis.</p>Formule :C29H20N6O2SCouleur et forme :SolidMasse moléculaire :516.57p53 Activator 3
CAS :<p>Potent p53 activator, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.</p>Formule :C30H37F3N4O4SCouleur et forme :SolidMasse moléculaire :606.7Apoptosis inducer 10
CAS :<p>Apoptosis inducer 10 is a potent apoptosis inducer with anti-proliferative activity.</p>Formule :C27H46N2O2Couleur et forme :SolidMasse moléculaire :430.67CAY10773
CAS :<p>CAY10773, a sorafenib derivative, inhibits cancer cells over non-cancerous ones and induces apoptosis or ferroptosis in T24 cells.</p>Formule :C22H17Cl2N5OCouleur et forme :SolidMasse moléculaire :438.31HL271
CAS :<p>HL271, a derivative of metformin, is a potent AMPK activator that increases AMPK phosphorylation. HL271 attenuates aging-associated cognitive impairment.</p>Formule :C13H17ClF3N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :351.76FD223
CAS :<p>FD223, a PI3Kδ inhibitor, is highly potent (IC50=1 nM) and selective, limiting AML cell growth by causing G1 arrest.</p>Formule :C17H12ClN5O2SCouleur et forme :SolidMasse moléculaire :385.83SEC
CAS :<p>SEC triggers ANXA7 GTPase via AMPK/mTORC1/STAT3, causing ITGB4-driven apoptosis in ITGB4-high cancer cells.</p>Formule :C22H23ClN2O5Couleur et forme :SolidMasse moléculaire :430.88KY1022
CAS :<p>KY1022 is a ras destabilizer. KY1022 targets the Wnt/ß-catenin pathway and inhibits development of metastatic colorectal cancer.</p>Formule :C17H19N3OSCouleur et forme :SolidMasse moléculaire :313.42RET-IN-16
CAS :<p>RET-IN-16: Selective RET inhibitor, IC50s 3.98-15.05 nM for various RET mutations; anticancer properties.</p>Formule :C31H29F3N8O2Couleur et forme :SolidMasse moléculaire :602.61IST5-002
CAS :<p>IST5-002: Potent Stat5a/b blocker, IC50 1.5μM/3.5μM, targets prostate cancer & CML.</p>Formule :C17H20N5O7PDegré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :437.34CB-64D
CAS :<p>CB-64D is a sigma2R selective agonist which releases calcium in human neuroblastoma cells and produces cell death in tumor cell lines.</p>Formule :C22H23NO2Couleur et forme :SolidMasse moléculaire :333.42AG311
CAS :<p>AG311 inhibits complex I; destabilizes HIF-1α; triggers necrosis in cancer cells, mitochondrial depolarization, superoxide, and calcium increase.</p>Formule :C17H15N5SCouleur et forme :SolidMasse moléculaire :321.4CDK6/PIM1-IN-1
CAS :<p>CDK6/PIM1-IN-1: A dual inhibitor for CDK6 (39 nM IC50) & PIM1 (88 nM), also targets CDK4 (3.6 nM IC50), halts AML cell growth, and induces apoptosis.</p>Formule :C25H28FN9Couleur et forme :SolidMasse moléculaire :473.55Theophylline sodium glycinate
CAS :<p>Theophylline sodium glycinate inhibits PDE3, treats asthma/COPD, blocks adenosine receptors, activates HDAC, reduces inflammation and induces apoptosis.</p>Formule :C9H12N5NaO4Couleur et forme :SolidMasse moléculaire :277.216TPB15
CAS :<p>TPB15, an oral Hh inhibitor, blocks Smo activity, arrests cell cycle, induces apoptosis, and shows potent antitumor effects with low toxicity.</p>Formule :C18H9Cl4N5OCouleur et forme :SolidMasse moléculaire :453.11ML132
CAS :<p>ML132 is an effective and selective inhibitor of caspase 1 (IC50: 0.316 nM).</p>Formule :C22H28ClN5O5Couleur et forme :SolidMasse moléculaire :477.94Anticancer agent 59
<p>Anticancer agent 59 suppresses various cancers, notably A549 at IC50 of 0.2 μM, induces apoptosis and disrupts mitochondria in mice.</p>Formule :C42H59NO6Couleur et forme :SolidMasse moléculaire :673.92673-A
CAS :<p>673-A inhibits ALDH1A, depletes ovarian CSCs, induces necroptosis, and reverses chemo resistance.</p>Formule :C15H13NOCouleur et forme :SolidMasse moléculaire :223.27STAT3-IN-10
CAS :<p>STAT3-IN-10 (A11) inhibits STAT3; halts tumor growth and triggers apoptosis in cancer cells (IC 50 = 5.18 μM).</p>Formule :C17H13NO5Couleur et forme :SolidMasse moléculaire :311.29Bcl-2-IN-9
CAS :<p>Bcl-2-IN-9: a novel, selective Bcl-2 inhibitor inducing apoptosis in leukemia with an IC50 of 2.9 μM; low cytotoxicity.</p>Formule :C27H31N7O3SCouleur et forme :SolidMasse moléculaire :533.65Bcl-2/Mcl-1-IN-3
CAS :<p>Bcl-2/Mcl-1-IN-3 is a Bcl-2/Mcl-1 inhibitor that acts on Mcl-1 (Ki: 0.14 μM) and Bcl-2 (Ki: 0.23 μM) and can be used in cancer research.</p>Formule :C27H26ClNO4Couleur et forme :SolidMasse moléculaire :463.95Vin-F03
CAS :<p>Vin-F03 protects pancreatic β-cells in type 2 diabetes research with an EC50 of 0.27 μM and prevents STZ-induced apoptosis.</p>Formule :C22H29N3Couleur et forme :SolidMasse moléculaire :335.49Mcl1-IN-1
CAS :<p>Mcl1-IN-1 is a myeloid cell factor 1 inhibitor (IC50=2.4 μM).</p>Formule :C23H18ClN3O4Couleur et forme :SolidMasse moléculaire :435.86NSC405640
CAS :<p>NSC405640 selectively inhibits MDM2-p53 interaction, restoring mutated p53 structure; halts growth of cells with normal p53. [1]</p>Formule :C12H10Cl2SnCouleur et forme :SolidMasse moléculaire :343.82CA224
CAS :<p>CA224: selective oral Cdk4-cyclin D1 inhibitor, IC50=6.2μM, promotes apoptosis, has antitumor effects.</p>Formule :C24H22N2OCouleur et forme :SolidMasse moléculaire :354.44Antitumor agent-55
CAS :<p>Antitumor agent-55 (5q) inhibits PC3 (IC50: 0.91 μM), blocks G1/S phase, induces apoptosis, and halts migration.</p>Formule :C32H34N6O4SCouleur et forme :SolidMasse moléculaire :598.72GGTI-2154
CAS :<p>GGTI-2154 is a potent, selective geranylgeranyltransferase I (GGTase I) inhibitor, boasting an IC50 of 21 nM and demonstrating over 200-fold selectivity against</p>Formule :C24H28N4O3Couleur et forme :SolidMasse moléculaire :420.5SS28
CAS :<p>SS28 inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase.</p>Formule :C18H20O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :284.35Tubulin/MMP-IN-2
CAS :<p>Tubulin/MMP-IN-2 blocks tubulin polymerization, MMP-2/-3/-9, induces apoptosis, aids cancer research, IC50: 24.95, 31.60, 22.37 µM.</p>Formule :C40H48NO11PCouleur et forme :SolidMasse moléculaire :749.78Verticillin A
CAS :<p>Verticillin A, an apoptosis inducer, inhibits Leiomyosarcoma and Malignant peripheral nerve sheath tumor growth.</p>Formule :C30H28N6O6S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :696.84(rel)-Oxaliplatin
CAS :<p>(rel)-Oxaliplatin, a DNA inhibitor, induces crosslinks, hinders replication/transcription, and triggers apoptosis; used in cancer studies.</p>Formule :C8H14N2O4PtCouleur et forme :SolidMasse moléculaire :397.29DRI-C21041
CAS :<p>DRI-C21041 is a potent inhibitor of the CD40/CD40L interaction, demonstrating an inhibitory concentration 50 (IC50) value of 0.31 μM.</p>Formule :C30H21N3O7SCouleur et forme :SolidMasse moléculaire :567.57DRI-C25441
CAS :<p>DRI-C25441 is a potent inhibitor of the CD40-CD40L interaction, exhibiting an IC50 value of 0.36 μM, and is capable of suppressing the immune response triggered</p>Formule :C31H21N3O6Couleur et forme :SolidMasse moléculaire :531.51AQX-016A
CAS :<p>AQX-016A, a potent SHIP1 agonist, is an oral analog of pelorol, 3x stronger, inhibits PI3K, TNFa, for inflammation research.</p>Formule :C22H32O2Couleur et forme :SolidMasse moléculaire :328.49YM-155 hydrochloride
CAS :<p>Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant that inhibits survivin promoter with an IC 50 of 0.54 nM[1].</p>Formule :C20H19ClN4O3Couleur et forme :SolidMasse moléculaire :398.85SK-7041
CAS :<p>SK-7041 is an effective HDAC inhibitor that acts by preferentially inhibiting class I HDAC1 and HDAC2.</p>Formule :C19H21N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :339.39PI3K/Akt/mTOR-IN-2
CAS :<p>Potent PI3K/AKT/mTOR inhibitor, selective for MDA-MB-231 cells with IC50 of 2.29 μM; induces arrest and apoptosis.</p>Formule :C17H13F2NODegré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :285.29MBM-17
CAS :<p>MBM-17 is a potent inhibitor of NIMA-related kinase 2 (Nek2,IC50 of 3 nM).</p>Formule :C28H28N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :480.56Anti-inflammatory agent 55
CAS :<p>Compound 9j (anti-inflammatory agent 55), a Coixol derivative, exhibits anti-inflammatory properties by inhibiting the NF-κB pathway and reducing the expression</p>Formule :C17H15N3O7Couleur et forme :SolidMasse moléculaire :373.32Estramustine phosphate
CAS :<p>Estramustine phosphate can be used to treat prostatic neoplasms; also has radiation protective properties.</p>Formule :C23H32Cl2NO6PCouleur et forme :SolidMasse moléculaire :520.38VO-OHPic
CAS :<p>VO-OHPic, a selective PTEN inhibitor (IC50 = 46 nM), reduces apoptosis and inflammation in doxorubicin-induced cardiomyopathy.</p>Formule :C12H10N2O8VCouleur et forme :SolidMasse moléculaire :361.16Anti-inflammatory agent 15
CAS :<p>Compound 29, anti-inflammatory and antimycobacterial, halts Mtb H37Rv and M299 growth; MIC50 at 2.3 and 7.8 μM. Blocks iNOS, TNF-α, IL-1β.</p>Formule :C17H20N2SCouleur et forme :SolidMasse moléculaire :284.42PDMP (hydrochloride)
CAS :<p>PDMP, a glucosylceramide synthase inhibitor with 4 stereoisomers, acts at 0.8μM; D-threo enantiomer also blocks lactosylceramide synthesis.</p>Formule :C23H39ClN2O3Couleur et forme :SolidMasse moléculaire :427.03TH1834 dihydrochloride
CAS :<p>TH1834 dihydrochloride is a specific Tip60 histone acetyltransferase inhibitor.</p>Formule :C33H42Cl2N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :641.63MpsBAY2a
CAS :<p>carcinoma cell proliferation.</p>Formule :C29H28N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :476.57PBENZ-DBRMD
CAS :<p>PBENZ-DBRMD inhibits DIO3, has anti-growth effects, and aids apoptosis, showing promise for cancer research.</p>Formule :C11H5Br2NO4Couleur et forme :SolidMasse moléculaire :374.97Apoptosis inducer 8
CAS :<p>Apoptosis inducer 8 is a galectin-1 (gal-1)-mediated apoptosis inducer and a PET imaging agent that significantly reduces gal-1 protein levels and can be used</p>Formule :C29H22ClN5O2Couleur et forme :SolidMasse moléculaire :507.97pan-HER-IN-1
CAS :<p>Compound C5: Irreversible, oral pan-HER inhibitor with low IC50s for EGFR/HERs; induces apoptosis and has antitumor effects.</p>Formule :C19H14BrN5OCouleur et forme :SolidMasse moléculaire :408.25Anti-inflammatory agent 22
CAS :<p>Compound 14a is an oral anti-inflammatory with an IC50 of 14.6 μM for TNF-α, preventing adipogenesis and reducing mouse limb lymphedema.</p>Formule :C22H16O6Couleur et forme :SolidMasse moléculaire :376.36MeOIstPyrd
CAS :<p>MeOIstPyrd is an anti-skin cancer agent that inhibits cell proliferation, migration, and spheroid formation through activation of the mitochondrial intrinsic</p>Formule :C14H16N4O2SCouleur et forme :SolidMasse moléculaire :304.37MI-192
CAS :<p>MI-192: Selective HDAC2/3 inhibitor, IC50=30/16 nM, induces apoptosis in myeloid leukemia, potential in leukemia/anti-stroke treatment.</p>Formule :C24H21N3O2Couleur et forme :SolidMasse moléculaire :383.44Arylquin 1
CAS :<p>Arylquin 1: a Par-4 secretagogue targeting vimentin; causes non-apoptotic cancer cell death via LMP.</p>Formule :C17H16FN3Couleur et forme :SolidMasse moléculaire :281.33MDM2/XIAP-IN-2
CAS :<p>MDM2/XIAP-IN-2 is a dual inhibitor targeting murine double minute 2 (MDM2) and X-linked inhibitor of apoptosis protein (XIAP).</p>Formule :C29H32N2O4SCouleur et forme :SolidMasse moléculaire :504.64GW-3333
CAS :<p>GW-3333 inhibits matrix metalloproteinases and TNF-Converting Enzyme, showing potential as an antiarthritic therapy.</p>Formule :C22H36N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.55MIR002
CAS :<p>MIR002: an oral POLA1/HDAC11 inhibitor with antitumor effects, enhances p53/p21, causes G1/S arrest, and triggers apoptosis.</p>Formule :C27H29NO5Couleur et forme :SolidMasse moléculaire :447.52AZD 1152 (hydrochloride)
CAS :<p>AZD 1152, an oral prodrug, becomes AZD 1152-HQPA in plasma, selectively inhibits Aurora kinase B (IC50=0.36 nM), and blocks tumor growth.</p>Formule :C26H33Cl2FN7O6PCouleur et forme :SolidMasse moléculaire :660.47VU0424465
CAS :<p>VU0424465 is a mGlu5-selective allosteric agonist.</p>Formule :C19H19FN2O2Couleur et forme :SolidMasse moléculaire :326.36SCAL-266
CAS :<p>SCAL-266, a potent inhibitor of mitochondrial complex I (CI), exhibits an IC50 of 0.83 μM.</p>Formule :C27H28F3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :511.54Pracinostat dihydrochloride
CAS :<p>Pracinostat dihydrochloride is a highly effective histone deacetylase (HDAC) inhibitor with IC₅₀ values ranging from 40 to 140 nM, utilized in cancer research. Additionally, it inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2) hydrolase activity with an EC₅₀ of less than 10 nM.</p>Formule :C20H32Cl2N4O2Couleur et forme :SolidMasse moléculaire :431.40IM-93
CAS :<p>IM-93 inhibits ferroptosis and NETosis with an IC< sub>50 of 0.45 μM for cell death inhibition [1].</p>Formule :C21H28N4O2Couleur et forme :SolidMasse moléculaire :368.47SLMP53-2
CAS :<p>SLMP53-2 is a mutant p53 reactivator that restores the wild-type-like conformation and DNA-binding ability of mutp53-Y220C through enhanced interaction with</p>Formule :C26H22N2O2Couleur et forme :SolidMasse moléculaire :394.47AP23464
CAS :<p>AP23464 inhibits Src/Abl kinases, effective on imatinib-resistant CML cells (IC50=14nM), blocks cell cycle, induces apoptosis, not against T315I mutant.</p>Formule :C26H30N5O2PCouleur et forme :SolidMasse moléculaire :475.52Epirubicin
CAS :<p>Epirubicin, a doxorubicin derivative, is an antineoplastic, inhibits topoisomerase, DNA/RNA synthesis, and Foxp3, reducing T cell activity.</p>Formule :C27H29NO11Couleur et forme :SolidMasse moléculaire :543.52CDK9-IN-18
CAS :<p>CDK9-IN-18: Potent CDK9 blocker, anticancer, induces apoptosis, low cellular activity.</p>Formule :C27H20N8OCouleur et forme :SolidMasse moléculaire :472.5STK17A/B-IN-1
CAS :<p>STK17A/B-IN-1 (compound 9) is an orally active, potent, and selective inhibitor of STK17A/B, demonstrating an IC50 of 23 nM for STK17A. This compound is utilized in tumor research.</p>Formule :C26H27N7OCouleur et forme :SolidMasse moléculaire :453.54RIPK3-IN-2
CAS :<p>RIPK3-IN-2 is a RIP3 inhibitor that can be used in studies of diseases caused by or associated with activated necrotic pathways.</p>Formule :C21H16ClN3O2S2Couleur et forme :SolidMasse moléculaire :441.95PQ1 Succinate
CAS :<p>PQ1 Succinate boosts GJIC and connexin in breast cancer cells without impacting normal mammary cells.</p>Formule :C25H28F3N3O6Couleur et forme :SolidMasse moléculaire :523.5bpV(phen)
CAS :<p>bpV(phen) is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor (IC50s: 343 nM, 920 nM, and 38 nM for PTP-β, PTP-1B, and PTEN).</p>Formule :C12H8KN2O5VDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :350.24NSC745885
CAS :<p>NSC745885 decreases EZH2, has selective cancer cell toxicity, and is studied for bladder and OSCC.</p>Formule :C14H6N2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :266.27RIPK1-IN-12
CAS :<p>RIPK1-IN-12: Strong RIPK1 blocker, hinders necroptosis; EC50=1.6 nM (human), 2.9 nM (mouse).</p>Formule :C24H26N4O3SCouleur et forme :SolidMasse moléculaire :450.55Antitumor agent-45
CAS :<p>Antitumor agent-45 has an inhibitory effect on c-Met expression and is able to block A549 cells in the G0/G1 and G2/M phases and induce apoptosis.</p>Formule :C28H17BrFN5O3Couleur et forme :SolidMasse moléculaire :570.37MMP-9-IN-5
CAS :<p>MMP-9-IN-5: MMP-9 and AKT inhibitor (IC50: 4.49 nM and 1.34 nM), induces apoptosis for cancer research.</p>Formule :C27H20IN3O4Couleur et forme :SolidMasse moléculaire :577.37PD1-PDL1-IN 1
CAS :<p>PD1-PDL1-IN 1 is a potent inhibitor of programmed cell death 1 (PD-1),and used as immune modulator.</p>Formule :C14H23N7O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :385.38S116836
CAS :<p>S116836 is a tyrosine kinase inhibitor.</p>Formule :C27H21F3N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.49Tubulin inhibitor 30
CAS :<p>Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.</p>Formule :C22H19N3O5Couleur et forme :SolidMasse moléculaire :405.4Lexibulin dihydrochloride
CAS :<p>Lexibulin 2HCl inhibits tubulin polymerization (IC50: 10-100 nM) and shows potent anti-cancer cytotoxicity and vascular disruption in vitro/vivo.</p>Formule :C24H32Cl2N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :507.46VEGFR-2-IN-28
CAS :<p>VEGFR-2-IN-28 is a potent inhibitor of VEGFR-2 (IC50: 0.83 μM). VEGFR-2-IN-28 induces apoptosis and exhibits antitumor effects.</p>Formule :C26H17N7O7Couleur et forme :SolidMasse moléculaire :539.46VS 8
CAS :<p>VS 8: potent oral VEGFR-2 inhibitor, anti-angiogenic, induces cancer cell apoptosis & migration, acts on CSCs.</p>Formule :C26H20F3N3O3Couleur et forme :SolidMasse moléculaire :479.45hCAIX-IN-12
CAS :<p>hCAIX-IN-12: hCAIX inhibitor; IC50: 0.74 μM (CAIX), 10.78 μM (CAII); impedes cell growth, triggers apoptosis, boosts ROS; potential in CRC research.</p>Formule :C18H14N4O3S2Couleur et forme :SolidMasse moléculaire :398.46MEK-IN-5
CAS :<p>MEK-IN-5: strong MEK inhibitor and NO donor, reduces pMEK/pERK dose/time-dependently, triggers apoptosis in MDA-MB-231 cells.</p>Formule :C29H27FN4O10S2Couleur et forme :SolidMasse moléculaire :674.67MYRA-A
CAS :<p>MYRA-A is an inducer of apoptosis in a Myc-dependent manner that acts by inhibiting Myc-driven transformation and disrupting MYC-Max interaction.</p>Formule :C19H20N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :340.37W146 TFA
CAS :<p>W146 TFA is a selective sphingosine-1-phosphate receptor 1 ( S1PR1 ) antagonist with an EC 50 value of 398 nM.</p>Formule :C18H28F3N2O6PCouleur et forme :SolidMasse moléculaire :456.399Psammaplysene A
CAS :<p>Psammaplysene A is a FOXO1a nuclear export inhibitor.</p>Formule :C27H35Br4N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :769.2Mitoguazone
CAS :<p>Mitoguazone is an antitumor agent, blocking SAM decarboxylase, disrupting polyamine synthesis, and hindering HIV DNA integration in immune cells.</p>Formule :C5H12N8Degré de pureté :97.47% - 98%Couleur et forme :SolidMasse moléculaire :184.2Antitumor agent-57
CAS :<p>Antitumor agent-57 (Compound 3o) is a potent NQO1-directed antitumor compound.</p>Formule :C20H15NO5Couleur et forme :SolidMasse moléculaire :349.34HSP90-IN-13
CAS :<p>HSP90-IN-13 (5k): potent HSP90 inhibitor, IC50 25.07 nM, targets EGFR/VEGFR-2/Topo-2, blocks MCF-7 G2/M cycle, induces apoptosis.</p>Formule :C26H21N5O3SCouleur et forme :SolidMasse moléculaire :483.54CDK8/19-IN-1
CAS :<p>CDK8/19-IN-1 is a selective and oral bioavailable CDK8/19 dual inhibitor (IC50s: 0.46 nM, 0.99 nM, and 270 nM for CDK8, CDK19, and CDK9).</p>Formule :C19H18N4O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.5Cyclamidomycin
CAS :<p>Cyclamidomycin is an antibiotic. It also functions as an inhibitor of nucleoside diphosphokinase of Escherichia coli.</p>Formule :C7H10N2OCouleur et forme :SolidMasse moléculaire :138.17DJ001
CAS :<p>DJ001: specific PTPσ inhibitor, non-competitive, IC50=1.43 μM, aids hematopoietic stem cell regeneration.</p>Formule :C15H12N2O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :268.27Anticancer agent 63
CAS :<p>Compound 3h fights various cancers; most effective on MCF-7 (IC50 3.4 μM). Triggers apoptosis; alters Bcl-2, IL-2, Caspase-3 levels, has antioxidant effects.</p>Formule :C17H24F3NOSeCouleur et forme :SolidMasse moléculaire :394.33NSC114792
CAS :<p>NSC114792 is a selective JAK3 inhibitor.</p>Formule :C26H32N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.62PARP14 inhibitor H10
CAS :<p>PARP14 inhibitor H10 is a selective inhibitor against PARP14 with IC50 of 490 nM</p>Formule :C24H27N7O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :557.58K-7174 dihydrochloride
CAS :<p>K-7174 dihydrochloride is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1β or TNF-</p>Formule :C33H50Cl2N2O6Degré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :641.67(E)-[6]-Dehydroparadol
CAS :<p>(E)-[6]-Dehydroparadol ((6)-Dehydroparadol), an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator.</p>Formule :C17H24O3Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :276.37PERK-IN-5
CAS :<p>PERK-IN-5: oral PERK inhibitor, IC50 of 2 nM; blocks p-eIF2α at 9 nM; hinders tumor growth in renal cancer model.</p>Formule :C25H26F2N4O3Couleur et forme :SolidMasse moléculaire :468.5CMC2.24
CAS :<p>CMC2.24 inhibits Ras and ERK1/2, fights pancreatic tumors in mice, blocks MMPs (IC50: 2-69 µM), and reduces osteoarthritis by stabilizing cartilage.</p>Formule :C26H21NO5Couleur et forme :SolidMasse moléculaire :427.45Caspase-3/7 activator 3
<p>Caspase-3/7 activator 3 triggers apoptosis with tumor selectivity and anti-proliferative effects.</p>Formule :C24H27NO5Couleur et forme :SolidMasse moléculaire :409.47PARP1-IN-31
CAS :<p>PARP1-IN-31 (compound 11f) is a PARP1 inhibitor with an IC₅₀ of 97 nM. It induces apoptosis and inhibits proliferation in lung cancer cell lines (e.g., A549).</p>Formule :C22H15ClFN3O2Degré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :407.83Irbesartan HCl
CAS :<p>Irbesartan: angiotensin II blocker; treats hypertension by inhibiting receptor binding.</p>Formule :C25H29ClN6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :465CAY10789
CAS :<p>CAY10789: potent CysLT1R antagonist (IC50 2.8 µM), GPBAR1 agonist (EC50 3 µM), reduces U937 cell adhesion, TNF-α, stable with promising pharmacokinetics.</p>Formule :C17H15NO2Couleur et forme :SolidMasse moléculaire :265.31Nafamostat hydrochloride
CAS :<p>Nafamostat hydrochloride is a synthetic serine protease inhibitor and is an anticoagulant.</p>Formule :C19H19Cl2N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.29EL-102
CAS :<p>EL-102 is a HIF1α inhibitor with anticancer activity that inhibits microtubule protein polymerization and can be used to study prostate cancer.</p>Formule :C19H16N2O3S2Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :384.47CSRM617
CAS :<p>CSRM617: selective ONECUT2 inhibitor, Kd 7.43 uM, binds OC2-HOX, induces apoptosis, tolerable in mouse prostate cancer model.</p>Formule :C10H13N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :255.23MCL-1/BCL-2-IN-4
CAS :<p>MCL-1/BCL-2-IN-4 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor.</p>Formule :C26H23BrN2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :555.44DCP-LA
CAS :<p>DCP-LA (FR236924), linoleic acid derivatives, selective and direct activation of PKCε.</p>Formule :C20H36O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :308.5Anti-inflammatory agent 11
CAS :<p>Potent anti-inflammatory compound 16 combats tuberculosis, inhibiting Mtb H37Rv and M299 (MICs: 1.3, 6.9 μM) and reduces NO, TNF-α, IL-1β production.</p>Formule :C14H14N4OSCouleur et forme :SolidMasse moléculaire :286.35RIPK1-IN-3
CAS :<p>RIPK1-IN-3 is a RIPK1 inhibitor, with anti-inflammatory proprieties.</p>Formule :C22H19F3N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :472.42Pentabromophenol
CAS :<p>Pentabromophenol (NSC-5717) suppressed TGF-β response by accelerating the turnover rate of TGF-β receptors.</p>Formule :C6HBr5ODegré de pureté :99.83%Couleur et forme :Monoclinic Prisms From Acetic Acid; Needles From Alcohol Physical Description Light Brown Powder Insoluble In Water (Ntp 1992)Masse moléculaire :488.59Ozarelix
CAS :<p>Ozarelix: a GnRH antagonist that induces apoptosis in advanced prostate cancer, modulates death receptors, and reduces sex hormones.</p>Formule :C72H96ClN17O14Couleur et forme :SolidMasse moléculaire :1459.09ATAD2-IN-1
CAS :<p>ATAD2-IN-1 (compound 19f) serves as a potent ATAD2 inhibitor (IC 50: 0.27 μM), capable of inducing apoptosis. Additionally, it suppresses c-Myc activation and impedes the migration of BT-549 cells [1].</p>Formule :C22H26N6O5Couleur et forme :SolidMasse moléculaire :454.48BJE6-106
CAS :<p>BJE6-106 (B106) is a potent, selective PKCδ inhibitor (IC50: 0.05 μM) and targets selectivity over classical PKCα (IC50: 50 μM).</p>Formule :C26H23NO2Couleur et forme :SolidMasse moléculaire :381.47SPRC
CAS :<p>"SPRC, a synthetic antioxidant, boosts H2S production, activates STAT3, and guards against doxorubicin heart damage."</p>Formule :C6H9NO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :159.21EGFR-IN-52
CAS :<p>EGFR-IN-52, a potent EGFR inhibitor, has IC50s: 0.358 μM (wild-type), 86.02 μM (L858R-TK), 432.67 μM (T790M-TK); induces cancer cell apoptosis.</p>Formule :C19H18N4O3SCouleur et forme :SolidMasse moléculaire :382.44AMC-01
CAS :<p>AMC-01 has potential antiviral activity and induces dose- and time-dependent inactivation of eIF2-α via phosphorylation of serine residue 51.</p>Formule :C27H27BrN2O6Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :555.42NSC 146109 hydrochloride
CAS :<p>NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.</p>Formule :C17H17ClN2SDegré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :316.85Benpyrine
CAS :<p>Benpyrine, an oral TNF-α inhibitor (KD 82.1 μM, IC50 0.109 μM), may help in inflammatory/autoimmune studies.</p>Formule :C16H16N6OCouleur et forme :SolidMasse moléculaire :308.34BTK-IN-9
CAS :<p>BTK-IN-9 reversibly inhibits BTK, disrupts mitochondria, boosts ROS, and triggers apoptosis in Z138 cells, impeding condyloma cell growth.</p>Formule :C25H19N7O4Couleur et forme :SolidMasse moléculaire :481.46T-3256336
CAS :<p>T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.</p>Formule :C31H45F2N5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :605.722,5-Dihydroxybiphenyl
CAS :<p>2,5-Dihydroxybiphenyl: a small molecule that induces trichothiodystrophy A protein dimerization, modulating TFIIH activity.</p>Formule :C12H10O2Degré de pureté :99.66%Couleur et forme :White To Grey-Brownish PowderMasse moléculaire :186.21PD-1/PD-L1-IN-14
CAS :<p>PD-1/PD-L1-IN-14 (compound 17) is an inhibitor of PD-1/PD-L1 interaction (IC50=27.8 nM).</p>Formule :C24H24N4O2Couleur et forme :SolidMasse moléculaire :400.47IDH1 Inhibitor 9
CAS :<p>IDH1 Inhibitor 9 (compound 11S) (2, 4, 8, 10 µM) induces apoptosis and causes cell cycle arrest in the S phase in a dose-dependent manner.</p>Formule :C26H30N4O3Couleur et forme :SolidMasse moléculaire :446.54LSD1-IN-14
CAS :<p>LSD1-IN-14: potent LSD1 inhibitor, IC50 0.89 μM; hinders A549/THP-1 cell growth, induces tumor cell apoptosis.</p>Formule :C21H24FN5Couleur et forme :SolidMasse moléculaire :365.45DRAK2-IN-1
CAS :<p>Drak2-in-1: ATP-competitive DRAK2 inhibitor; IC50 = 3 nM, KI = 0.26 nM; affects DRAK1 (IC50 = 51 nM).</p>Formule :C21H20N4O3Couleur et forme :SolidMasse moléculaire :376.41Quinate
CAS :<p>Quinate: oral antiarrhythmic, inhibits P450db, blocks K+ channels (IC50 19.9 μM), used in malaria research.</p>Formule :C26H36N2O9Couleur et forme :SolidMasse moléculaire :520.579Tubulin/HDAC-IN-1
CAS :<p>Tubulin/HDAC-IN-1 is a dual inhibitor for tubulin & HDAC8, blocking polymerization & targeting HDAC8 (IC50: 150 nM), and induces cancer cell apoptosis.</p>Formule :C21H18N4O3Couleur et forme :SolidMasse moléculaire :374.39EGFR-IN-46
CAS :<p>EGFR-IN-46: Potent EGFR/FAK inhibitor (IC50: 20.17 & 14.25 nM), curbs cancer cell growth, triggers apoptosis.</p>Formule :C27H32F3N3O3Couleur et forme :SolidMasse moléculaire :503.56SB-218078
CAS :<p>SB-218078 is less potently inhibits Cdc2 (IC50: 250 nM) and PKC (IC50: 1000 nM).</p>Formule :C24H15N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :393.39Anticancer agent 67
CAS :<p>Anticancer agent 67 is a ciprofloxacin analogue, an anticancer agent that induces apoptosis and increases sub-G1 cell populations in MCF-7 cells.</p>Formule :C26H24F2N6O2S2Couleur et forme :SolidMasse moléculaire :554.63Atopaxar Hydrobromide
CAS :<p>Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.</p>Formule :C29H39BrFN3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :608.54Quinidine Monosulfate
CAS :<p>Quinidine Monosulfate: an oral antiarrhythmic, CYP450db inhibitor, K+ blocker (IC50 19.9 μM), used in malaria research.</p>Formule :C40H50N4O8SCouleur et forme :SolidMasse moléculaire :746.92HLI 373
CAS :<p>HLI373: potent Hdm2 (ubiquitin ligase) inhibitor, induces apoptosis in tumor cells, has antimalarial properties.</p>Formule :C18H23N5O2Couleur et forme :SolidMasse moléculaire :341.41Caspase-9 Inhibitor III
CAS :<p>Caspase-9 Inhibitor III (Ac-LEHD-cmk) blocks caspase-9, protects against ischemic heart damage.</p>Formule :C24H35ClN6O9Couleur et forme :SolidMasse moléculaire :587.02PI3Kδ-IN-10
CAS :<p>PI3Kδ-IN-10 is a highly potent and orally active PI3Kδ inhibitor (IC50= 2 nM).</p>Formule :C19H16ClN9Couleur et forme :SolidMasse moléculaire :405.84DX2-201
CAS :<p>DX2-201 is a potent and selective inhibitor of oxidative phosphorylation (OXPHOS) complex I (IC50: 312 nM) and exhibits anticancer activity.</p>Formule :C18H28N2O6S2Couleur et forme :SolidMasse moléculaire :432.55Topoisomerase I inhibitor 3
CAS :<p>Topoisomerase I (Compound ZML-14) inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2/M phase.</p>Formule :C18H14FNO3Couleur et forme :SolidMasse moléculaire :311.31Sanazole
CAS :<p>Sanazole is a 3-nitrotriazole cpd. It can affect the human cervical cancer cell line.</p>Formule :C7H11N5O4Couleur et forme :SolidMasse moléculaire :229.19RET-IN-8
CAS :<p>RET-IN-8 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.</p>Formule :C27H30N6O3Couleur et forme :SolidMasse moléculaire :486.57DAT-230
CAS :<p>DAT-230 is a microtubule inhibitor effective against cancer cells, causing cell cycle arrest and apoptosis via caspase activation.</p>Formule :C20H21NO2SCouleur et forme :SolidMasse moléculaire :339.45RET-IN-20
<p>RET-IN-20: potent RET inhibitor (IC50 = 13.7 nM), reduces p-Ret/p-Shc, induces apoptosis, anti-tumor effects.</p>Formule :C32H33FN6O4Couleur et forme :SolidMasse moléculaire :584.64EGFR-IN-59
CAS :<p>EGFR-IN-59: EGFR inhibitor, IC50 = 190 nM, induces apoptosis, cytotoxic to A549 cells (IC50 = 8.62 μM) and WI38 cells (IC50 = 52.6 μM). Use: Various cancers.</p>Formule :C27H23N5O4SCouleur et forme :SolidMasse moléculaire :513.57
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