Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5598 produits trouvés pour "Apoptose"
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NS3694
CAS :<p>NS3694 is an inhibitor of apoptosis and inhibits apoptosome formation and caspase activation.</p>Formule :C15H10ClF3N2O3Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :358.7Oxythiamine
CAS :<p>Oxythiamine (Hydroxythiamin) is a TK inhibitor that inhibits cancer cell proliferation, induces cell cycle arrest, and induces apoptosis.</p>Formule :C12H16N3O2SDegré de pureté :96.14% - 99.51%Couleur et forme :SolidMasse moléculaire :266.34HFY-4A
CAS :<p>HFY-4A is a novel HDAC inhibitor.HFY-4A has antitumour activity and has shown antiproliferative activity in breast cancer cells.</p>Formule :C20H19N3O2Degré de pureté :98.66% - 99.22%Couleur et forme :SoildMasse moléculaire :333.385-LOX-IN-2
CAS :<p>5-LOX-in-2: a 5-lipoxygenase inhibitor with IC50 of 0.33 μM, reduces kidney cancer cell activity, induces apoptosis.</p>Formule :C17H16O4Degré de pureté :98.74%Couleur et forme :SoildMasse moléculaire :284.31Anticancer agent 130
<p>Anticancer agent 130 (compound 8d) significantly induces apoptosis in A549 cells [1].</p>Formule :C38H46FN5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :671.8Asparanin A
CAS :<p>Asparanin A, an apoptosis inducer with anticancer properties, arrests the cell cycle in the G0/G1 phase via the mitochondria and PI3K/AKT signaling pathways.</p>Formule :C39H64O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :740.92Caerin 1.1 TFA
<p>Caerin 1.1 TFA, a host defense peptide derived from the Australian tree frog Litoria's glandular secretions, exhibits anti-proliferative effects on HeLa cells</p>Degré de pureté :98%Couleur et forme :Odour SolidFerroptosis-IN-3
<p>Ferroptosis-IN-3 (Compound 25), a ferroptosis inhibitor, demonstrates potent activity by inhibiting RSL3-induced ferroptosis in HT-1080 cells (EC50: 8.6 nM).</p>Degré de pureté :98%Couleur et forme :Odour SolidTAT-BH4 (Bcl-xL)
<p>TAT-BH4 (Bcl-xL), primarily localized at the mitochondria, inhibits apoptotic cell death.</p>Formule :C159H268N58O45Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3712.19Pyridinium bisretinoid A2E TFA
CAS :<p>Pyridinium bisretinoid A2E (A2E) TFA, a fluorophore derived from retinal pigment epithelium (RPE) lipofuscin, initiates blue-light-induced apoptosis, mediates</p>Formule :C44H58F3NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :705.93Antitumor agent-112
<p>Antitumor agent-112 (compound 3a) is a potent antitumor agent that induces apoptosis and exhibits cytotoxic activity on A549 cells, with an IC50 value of 91.35</p>Formule :C18H17ClN4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :388.87TAT-NEP1-40 TFA
<p>TAT-NEP1-40 TFA, a blood-brain barrier-permeable peptide, safeguards PC12 cells against oxygen and glucose deprivation (OGD) and fosters neurite outgrowth.</p>Formule :C268H438N88O77·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :6124.89 (free base)TP4 (Nile tilapia piscidin)
CAS :<p>TP4 (Nile tilapia piscidin) is an orally active piscidin-like antimicrobial peptide that exhibits inhibition of various gram-positive and negative bacterial</p>Formule :C135H226N50O27Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2981.56Antitumor agent-113
<p>Antitumor Agent-113 exhibits cytotoxicity in A549 cells, with an IC50 of 46.60 μM, and induces apoptosis, making it applicable for research in non-small cell</p>Formule :C21H22ClN5O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :443.95cpm-1285
CAS :<p>CPM-1285 induces apoptosis by effectively inhibiting the function of intracellular Bcl-2 and associated death antagonists.</p>Formule :C153H240N44O42SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :3399.88HNPMI
CAS :<p>HNPMI is an epidermal growth factor receptor inhibitor that promotes apoptosis and is used in the study of colorectal cancer.</p>Formule :C22H20N2O3Degré de pureté :97.19%Couleur et forme :SoildMasse moléculaire :360.414-hydroperoxy cyclophosphamide
CAS :<p>4-hydroperoxy cyclophosphamide (4-OOH-CY) induces hepatotoxicity. It increases ghrelin levels and enhances inflammatory factors and oxidative markers.</p>Formule :C7H15Cl2N2O4PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :293.09Thrombospondin-1 (1016-1023) (human, bovine, mouse)
CAS :<p>Thrombospondin-1 (1016-1023) (human, bovine, mouse) is part of Thrombospondin-1 (TSP-1), a peptide with CD47 agonism.</p>Formule :C56H81N13O10SDegré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :1128.39ASK1-IN-4
CAS :<p>ASK1-IN-4 is an ASK1 inhibitor, IC50 = 0.2 μM.</p>Formule :C18H14BrNO4S2Degré de pureté :99.756%Couleur et forme :SolidMasse moléculaire :452.34Tralokinumab
CAS :<p>Tralokinumab: human IgG4 monoclonal antibody, blocks IL-13, may treat atopic dermatitis.</p>Degré de pureté :SDS-PAGE:95% SEC-HPLC:99.99%Couleur et forme :LiquidMasse moléculaire :144.14 kDa5α-dihydro Levonorgestrel
CAS :<p>5α-dihydro Levonorgestrel is a metabolite of the synthetic progestin levonorgestrel .</p>Formule :C21H30O2Couleur et forme :SolidMasse moléculaire :314.469HKB99
CAS :<p>HKB99 suppresses NSCLC growth, metastasis, and overcomes erlotinib resistance.</p>Formule :C23H18N2O6SDegré de pureté :97.35% - 97.35%Couleur et forme :SolidMasse moléculaire :450.46Urelumab
CAS :<p>"Urelumab (BMS-66513), a humanized IgG4 mAb CD137 agonist, boosts T-cell/NK cell-mediated cytotoxicity and anti-tumor activity."</p>Degré de pureté :97.70%Couleur et forme :LiquidMasse moléculaire :145.90 kDa2-aminobenzo[d]thiazol-6-ol
CAS :<p>2-aminobenzo[d]thiazol-6-ol: antimicrobial, antioxidant, anticancer; may trigger cancer cell apoptosis.</p>Formule :C7H6N2OSDegré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :166.2ILS-920
CAS :<p>ILS-920, a Rapamycin analog, has reduced immunosuppression, enhanced neuroprotection, and preferentially binds FKBP52 and L-type VGCC β1.</p>Formule :C57H86N2O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1023.3Bleomycin A5
CAS :<p>Bleomycin A5, or Pingyangmycin, is an oral glycopeptide antibiotic and acts as an antineoplastic and apoptosis inducer.</p>Formule :C57H89N19O21S2Couleur et forme :SolidMasse moléculaire :1440.56Prodigiosin
CAS :<p>Prodigiosin is a secondary metabolite of Symbiotic bacteria. It also has anti-fungal and anti-cancer activity.</p>Formule :C20H25N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :323.44Tubulin polymerization-IN-45
<p>Tubulin polymerization-IN-45, a tubulin-targeting agent, acts as a tubulin polymerization inhibitor by binding to the tubulin's colchicine site.</p>Formule :C20H18N4O3Couleur et forme :SolidMasse moléculaire :362.38Destruxin B
CAS :<p>Destruxin B: cyclic peptide from Metarhizium fungus, induces apoptosis in lung cancer via mitochondrial pathway.</p>Formule :C30H51N5O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :593.766Pamrevlumab
CAS :<p>FG-3019 (Pamrevlumab), a human antibody, targets CTGF, potentially treating idiopathic pulmonary fibrosis.</p>Degré de pureté :100% (SEC-HPLC) - 95%Couleur et forme :LiquidThalidomide-5-propoxyethanamine
CAS :<p>Thalidomide-5-propoxyethanamine acts as a cereblon (CRBN) ligand derived from Thalidomide, and it serves the purpose of recruiting the CRBN protein.</p>Formule :C18H21N3O5Couleur et forme :SolidMasse moléculaire :359.38YL5084
CAS :<p>YL5084 is a selective JNK2/3 inhibitor with IC50s: JNK2 (70 nM), JNK3 (84 nM), and antiproliferative, apoptosis-inducing effects.</p>Formule :C35H36N8O2Couleur et forme :SolidMasse moléculaire :600.71CPTH2 (hydrochloride) (357649-93-5 free base)
CAS :<p>CPTH2 is an inhibitor of the HAT activity of Gcn5.</p>Formule :C14H15Cl2N3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :328.267-Methoxy-1-tetralone
CAS :<p>7-Methoxy-1-tetralone may have insecticidal activity.</p>Formule :C11H12O2Degré de pureté :99.85% - 99.89%Couleur et forme :White CrystalMasse moléculaire :176.21FLT3-IN-29
<p>FLT3-IN-29 (Compound MY-10) is an FLT3 inhibitor with IC50 values of 6.5 nM and 10.3 nM for FLT3-ITD and FLT3-D835Y mutants, respectively. It induces cell cycle arrest at the G0/G1 phase and effectively triggers apoptosis (Apoptosis). Additionally, FLT3-IN-29 reduces reactive oxygen species (ROS) and mitochondrial membrane potential (MMP), displaying anti-leukemic properties.</p>Formule :C25H30N6O2Couleur et forme :SolidMasse moléculaire :446.545KB02-SLF
<p>KB02-SLF, a molecular glue, degrades nuclear FKBP12 by modifying E3 ligase DCAF16 and extends protein degradation.</p>Formule :C50H65ClN4O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :949.52Fosbretabulin [free base]
CAS :<p>Fosbretabulin is a natural cis-stilbene that interferes with cellular tubulin dynamics and selectively destroys tumor blood vessels.</p>Formule :C18H21O8PCouleur et forme :SolidMasse moléculaire :396.33Aloeresin G
CAS :<p>Aloeresin G, a chromone glycoside isolated from Aloe, exhibits a moderate inhibitory effect on TNFα-induced NF-κB transcriptional activity, evidenced by an IC50</p>Formule :C29H30O10Couleur et forme :SolidMasse moléculaire :538.54Anticancer agent 153
<p>Anticancer Agent 153 (Compound 3) promotes apoptosis through the generation of Reactive Oxygen Species (ROS) and elevates the loss of Mitochondrial Membrane</p>Formule :C16H11Cl2N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :364.18Antitumor agent-103
<p>Antitumor Agent-103 (compound 24l) induces apoptosis and possesses antiproliferative and anti-colony formation properties.</p>Formule :C36H36N8O9S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :788.85Anticancer agent 132
<p>Compound Rh1 (Anticancer agent 132) acts as an inducer of apoptosis and autophagy, exhibiting both antitumor and antimetastatic activities.</p>Formule :C24H16Cl3F3N5ORhDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :656.68Thalidomide-O-amido-PEG3-C2-NH2
CAS :<p>Thalidomide-O-amido-PEG3-C2-NH2 is a cereblon ligand-linker for PROTACs with a 3-unit PEG.</p>Formule :C23H30N4O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.51β-Amyloid (1-40) (rat)
CAS :<p>Rat form of the beta-Amyloid (1-40) peptide</p>Formule :C190H291N51O57SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4233.76Antitumor photosensitizer-4
<p>Antitumor Photosensitizer-4 (compound 10b), a conjugate of dasatinib and imatinib, serves as a potent tyrosine kinase inhibitor (TKI) targeting ABCG2.</p>Formule :C65H77ClN12O11SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1269.9TAT-GluN2BCTM
CAS :<p>TAT-GluN2BCTM is a membrane-permeable peptide that selectively targets active DAPK1 (Death-associated protein kinase 1) for lysosomal degradation, thereby</p>Formule :C224H374N86O54Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :5135.91ZZM-1220
<p>ZZM-1220, a covalent inhibitor of histone lysine methyltransferase G9a/GLP, exhibits IC50 values of 458 nM for G9a and 924 nM for GLP.</p>Formule :C25H29N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :447.53Cholicamideβ
<p>Cholicamideβ (compound 6), a self-assembling small molecule cancer vaccine adjuvant, forms low cytotoxicity virus-like particles and upon binding to peptide</p>Formule :C55H94N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :879.34VEGFR-2-IN-68
<p>VEGFR-2-IN-68 (13b) is an inhibitor of VEGFR-2 with an IC50 value of 41.51 nM. It can induce apoptosis and cause G2/M cell cycle arrest, as well as exhibit anti-cancer metastasis properties.</p>Formule :C27H25N5O2SCouleur et forme :SolidMasse moléculaire :483.1729EGFR-IN-78
<p>EGFR-IN-78 (compound A5), a 2-aminopyrimidine derivative, serves as a reversible EGFR C797S-TK inhibitor and an apoptosis inducer.</p>Formule :C23H32BrN7O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :550.51HMGB1-IN-1
<p>HMGB1-IN-1 (compound 6) exhibits potent inhibition of NO production in RAW264.7 cells, with an IC50 of 15.9 ± 0.6 μM, and effectively disrupts the HMGB1/NF-κB/</p>Formule :C57H75N3O15Couleur et forme :SolidMasse moléculaire :1042.22
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