Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(135 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(93 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6225 produits trouvés pour "Apoptose"
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HNPMI
CAS :HNPMI is an epidermal growth factor receptor inhibitor that promotes apoptosis and is used in the study of colorectal cancer.Formule :C22H20N2O3Degré de pureté :97.19%Couleur et forme :SoildMasse moléculaire :360.41Anticancer agent 134
Anticancer Agent 134 (Compound 6a), an environment-sensitive fluorescent probe, induces apoptosis and selectively differentiates between tumor and normalFormule :C34H36ClN7O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :690.28TAT-NEP1-40 acetate
TAT-NEP1-40 acetate, a potential therapeutic for axonal regeneration and functional recovery post-stroke, safeguards PC12 cells from oxygen and glucoseFormule :C268H438N88O77·xC2H4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :6124.89 (free base)Antitumor photosensitizer-4
Antitumor Photosensitizer-4 (compound 10b), a conjugate of dasatinib and imatinib, serves as a potent tyrosine kinase inhibitor (TKI) targeting ABCG2.Formule :C65H77ClN12O11SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1269.9Dimethachlor
CAS :Dimethachlor is a pesticide and herbicide used in wetland areas.Formule :C13H18ClNO2Couleur et forme :SolidMasse moléculaire :255.74TAT-GluN2BCTM
CAS :TAT-GluN2BCTM is a membrane-permeable peptide that selectively targets active DAPK1 (Death-associated protein kinase 1) for lysosomal degradation, therebyFormule :C224H374N86O54Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :5135.91Cholicamideβ
Cholicamideβ (compound 6), a self-assembling small molecule cancer vaccine adjuvant, forms low cytotoxicity virus-like particles and upon binding to peptideFormule :C55H94N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :879.34AZD5582 dihydrochloride
CAS :Dimeric Smac mimetic inhibits XIAP, cIAP1/2 (IC50: 15/15/21 nM); binds BIR3 domain; degrades cIAPs; induces apoptosis in cancer cells; shrinks tumors in mice.Formule :C58H80Cl2N8O8Couleur et forme :SolidMasse moléculaire :1088.23Antitumor agent-41
Antitumor Agent-41 (Compound N-12) exhibits potent antitumor properties, demonstrating significant antimigration and anti-invasion activities.Formule :C64H109IN2O21Couleur et forme :SolidMasse moléculaire :1369.46EGFR-IN-78
EGFR-IN-78 (compound A5), a 2-aminopyrimidine derivative, serves as a reversible EGFR C797S-TK inhibitor and an apoptosis inducer.Formule :C23H32BrN7O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :550.51GPX4-IN-7
GPX4-IN-7 (Compound 31), an indirubin derivative, serves as a ferroptosis inducer in colon cancer treatment.Formule :C25H23ClN4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :478.93Thalidomide-O-amido-PEG2-C2-NH2
CAS :Thalidomide-O-amido-PEG2-C2-NH2, which combines an E3 ligase ligand with a linker, serves as an immunomodulator for cancer treatment.Formule :C21H26N4O8Couleur et forme :SolidMasse moléculaire :462.459fac-[Re(CO)3(L6)(H2O)][NO3]
Compound 6, fac-[Re(CO)3(L6)(H2O)][NO3], a rhenium(I) tricarbonyl aqua complex, serves as an anticancer agent by disrupting mitochondrial function.Formule :C24H14N5O7ReSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :702.67Anticancer agent 133
Compound Rh2 (Anticancer agent 133) is a cytotoxic and antimetastatic agent that induces cell cycle arrest, apoptosis, and autophagy.Formule :C24H19Cl3N5ORhDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :602.71Antimycin A2c
Anticancer Agent 141 (Compound AE), an antimycin alkaloid, exhibits inhibitory potential against HPV-infected cervical cancer.Formule :C28H40N2O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :548.63Anti-inflammatory agent 45
Compound 2v (Anti-inflammatory agent 45) demonstrates anticancer properties with direct inhibitory impacts on the proliferation of various blood malignancies,Formule :C25H22BrNO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :512.35LSD1-IN-26
LSD1-IN-26 (12u) is a potent LSD1 inhibitor (IC50=25.3 nM), also inhibits MAO-A/B, induces apoptosis in MGC-803, for gastric cancer research.Formule :C27H25Cl2F2N3OCouleur et forme :SolidMasse moléculaire :516.41HTH-01-091 TFA
HTH-01-091 TFA: Potent, selective MELK inhibitor (IC50=10.5 nM); also targets PIM1/2/3, RIPK2, DYRK3, smMLCK, CLK2; used in breast cancer research.Formule :C28H29Cl2F3N4O4Couleur et forme :SolidMasse moléculaire :613.46BAY 1892005
CAS :BAY 1892005 is a p53 protein modulator that targets the p53 condenser for the study of diseases associated with misfolded p53 proteinFormule :C11H8ClFN2OSDegré de pureté :99.42%Couleur et forme :SoildMasse moléculaire :270.71BK60106
BK60106 is a selective and direct inhibitor of the transmembrane protein CD99, which causes cell death in Ewing Sarcoma cells.Formule :C15H15FN6O3Degré de pureté :99.30% - >99.99%Couleur et forme :SolidMasse moléculaire :346.32Holothurin A
CAS :Holothurin A is a triterpene glycoside.Formule :C54H86NaO27SCouleur et forme :SolidMasse moléculaire :1222.35-LOX-IN-8
5-LOX-IN-8 is a 5-LOX inhibitor with anti-inflammatory properties. It suppresses IL-6, IL-1β, TNF-α, and IFN-γ in macrophages and reduces IL-8 secretion in SW480 cells. Additionally, 5-LOX-IN-8 decreases the disease activity index in DSS colitis models. This compound is applicable for research in inflammatory bowel disease (IBD).Couleur et forme :Odour SolidBM-962
CAS :BM-962 (Compound 31) is a potent small-molecule inhibitor with an IC50 value of 4 nM (Ki=0.8 nM) for Bcl-2 and an IC50 of 3.9 nM (Ki<1 nM) for Bcl-xL. It inhibits H1417 and H146 cell lines with IC50 values of 9 and 13 nM, respectively, and shows potential for use in cancer research.Formule :C53H58ClF3N6O7S3Couleur et forme :SolidMasse moléculaire :1079.71Sandacanol
CAS :Sandacanol (Sandranol) is an olfactory receptor (OR10H1) agonist.Sandacanol induces cell cycle arrest and partial apoptosis in bladder cancer cells.Formule :C14H24ODegré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :208.34MitoEbselen-2 chloride
CAS :MitoEbselen-2 mitigates radiation, cuts lipid hydroperoxides, blocks cell death, and boosts survival in irradiated mice.Formule :C35H30ClN2O2PSeCouleur et forme :SolidMasse moléculaire :656.01DS-5272
CAS :DS-5272 is a potent and orally active inhibitor of p53-MDM2 interaction.Formule :C34H38Cl2F2N6O2SCouleur et forme :SolidMasse moléculaire :703.67BM-1074
CAS :BM-1074 is a potent and highly efficacious inhibitor of Bcl-2/Bcl-xL with Ki value of < 1nM [1].Formule :C50H57ClN8O7S3Couleur et forme :SolidMasse moléculaire :1013.69Borrelidin
CAS :Borrelidin (Treponemycin) is an inhibitor of trehalose-6-phosphate synthase, a nitrogen-containing macrolide antibiotic isolated from Streptomyces rochei.Formule :C28H43NO6Degré de pureté :98%Couleur et forme :White To Off-White PowderMasse moléculaire :489.64SM-164 Hydrochloride
SM-164 Hydrochloride: Smac mimetic, cell-permeable, binds XIAP BIR2 and BIR3, IC50 of 1.39 nM, potent XIAP antagonist.Formule :C62H85ClN14O6Couleur et forme :SolidMasse moléculaire :1157.88Oxythiamine
CAS :Oxythiamine (Hydroxythiamin) is a TK inhibitor that inhibits cancer cell proliferation, induces cell cycle arrest, and induces apoptosis.
Formule :C12H16N3O2SDegré de pureté :96.14% - 99.51%Couleur et forme :SolidMasse moléculaire :266.34Pomstafib-2
CAS :Pomstafib-2, a potent and selective inhibitor of STAT5b, reduces pSTAT5b expression and effectively induces apoptosis [1] [2].Formule :C52H66N2O20P2Couleur et forme :SolidMasse moléculaire :1101.03NS3694
CAS :NS3694 is an inhibitor of apoptosis and inhibits apoptosome formation and caspase activation.Formule :C15H10ClF3N2O3Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :358.7Ref: TM-T22119
1mg37,00€2mg52,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg111,00€25mg227,00€50mg329,00€100mg512,00€500mg1.093,00€27-O-(tert-Butyldimethylsilyl)withaferin A
CAS :Compound 9a, a withanolide, induces apoptosis and has anti-cancer properties.Formule :C34H52O6SiCouleur et forme :SolidMasse moléculaire :584.86Thalidomide-O-C10-NH2
CAS :Thalidomide-O-C10-NH2: synthetic cereblon-based E3 ligase ligand-linker for PROTACs.Formule :C23H31N3O5Couleur et forme :SolidMasse moléculaire :429.517MK-0731
CAS :MK-0731 inhibits kinesin spindle protein, disrupting mitosis and triggering apoptosis in KSP-overexpressing tumor cells.Formule :C25H28F3N3O2Couleur et forme :SolidMasse moléculaire :459.5Kurzipene D
CAS :Kurzipene D: anticancer, induces apoptosis, halts HepG2 at S phase, anti-tumor in zebrafish, inhibits tumor growth and spread.Formule :C26H36O8Couleur et forme :SolidMasse moléculaire :476.56Thalidomide-O-C2-acid
CAS :Thalidomide-O-C2-acid: E3 ligase ligand-linker for PROTAC, with cereblon-derived Thalidomide component.Formule :C16H14N2O7Couleur et forme :SolidMasse moléculaire :346.2916Schisandronic acid
CAS :Schisandronic acid is a triterpenoid acid isolated from the stems of Schisandra propinqua.Formule :C30H46O3Couleur et forme :SolidMasse moléculaire :454.68Zapalog
CAS :Zapalog: photocleavable dimerizer controlling instant protein interactions.Formule :C58H73N7O15Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1108.24Fascaplysin chloride
CAS :Fascaplysin inhibits CDK4/D1 (IC50=0.35μM), triggers caspase-activated autophagy-apoptosis crosstalk, and blocks PI3K/AKT/mTOR in HL-60 cells.Formule :C18H11ClN2OCouleur et forme :SolidMasse moléculaire :306.75Antitumor agent-36
Antitumor agent-36: potent anti-cancer; causes DNA damage, triggers apoptosis, enhances immune response by upregulating T cells.Formule :C32H30Cl2N2O6PtCouleur et forme :SolidMasse moléculaire :804.58FGA139
FGA139 is an inhibitor of cysteine proteases, specifically targeting cathepsin B and L with IC50 values of 4.98 μM and 3.14 μM, respectively. It reduces the production of NO in LPS-induced RAW264.7 cells and lowers TNFα levels in microglia, demonstrating antioxidant and anti-inflammatory properties. Additionally, FGA139 enhances the secretion of neuroprotective metabolites such as purines and linoleic acid in LPS-stimulated microglia. This compound is applicable in the study of neuroinflammatory diseases.
Formule :C48H58BF2N7O5Couleur et forme :SolidMasse moléculaire :861.45605Ilicicolin A
CAS :Ilicicolin A is a useful organic compound for research related to life sciences. The catalog number is T125289 and the CAS number is 22581-06-2.Formule :C23H31ClO3Couleur et forme :SolidMasse moléculaire :390.95Antibiotic DC 81
CAS :DC 81: Streptomyces-derived antitumor antibiotic, potent nucleic acid synthesis inhibitor, binds DNA sequences, forms covalent adducts.Formule :C13H14N2O3Couleur et forme :SolidMasse moléculaire :246.262,4-D sodium salt
CAS :Sodium 2,4-dichlorophenoxyacetate: selective herbicide, controls broadleaf weeds by disrupting growth and protein/DNA synthesis.Formule :C8H5Cl2NaO3Couleur et forme :SolidMasse moléculaire :243.02Canfosfamide
CAS :Canfosfamide, a prodrug activated by GSTP1-1, induces apoptosis and inhibits DNA-PK, producing an alkylating agent for cancer research.Formule :C26H40Cl4N5O10PSCouleur et forme :SolidMasse moléculaire :787.47OICR12694 TFA
CAS :OICR12694 (JNJ-65234637) TFA, an orally active B cell lymphoma 6 (BCL6) inhibitor [1], demonstrates effectiveness in targeting BCL6 pathways.Formule :C29H28ClF3N8O4·xC2HF3O2Couleur et forme :SolidRET-IN-4
CAS :RET-IN-4: Oral RET inhibitor, IC50 ~1 nM for variants. Selective over JAK2/FLT3. Potent anticancer use.Formule :C27H31FN10O2Couleur et forme :SolidMasse moléculaire :546.611DMUP
CAS :DMUP inhibits CD47-SIRPα, induces apoptosis, boosts macrophage activity in A549 cells, and has antitumor properties.Formule :C24H24Cl2N2O10PtCouleur et forme :SolidMasse moléculaire :766.45Anagrelide hydrochloride monohydrate
CAS :Anagrelide HCl monohydrate is a platelet-reducing imidazoquinazoline for ET and PV research.Formule :C10H10Cl3N3O2Couleur et forme :SolidMasse moléculaire :310.56
