Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5598 produits trouvés pour "Apoptose"
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MD-222
CAS :<p>MD-222: a first-in-class, highly potent PROTAC that degrades MDM2, activates p53, and exhibits anticancer properties.</p>Formule :C48H47Cl2FN6O6Couleur et forme :SolidMasse moléculaire :893.84BOC-D-FMK
CAS :<p>Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 μM).</p>Formule :C11H18FNO5Degré de pureté :97.02%Couleur et forme :SolidMasse moléculaire :263.26Sotigalimab
CAS :<p>Sotigalimab (APX 005) is a monoclonal antibody targeting CD40 with anticancer activity for the study of metastatic pancreatic cancer.</p>Degré de pureté :98.50% - 98.50%Couleur et forme :LiquidEpoprostenol sodium
CAS :<p>Epoprostenol sodium (Prostaglandin I2 sodium salt) is a vasodilator and a synthetic prostacyclin that can be used to study pulmonary hypertension.</p>Formule :C20H31NaO5Degré de pureté :98%Couleur et forme :White Crystalline PowderMasse moléculaire :374.45Z-DQMD-FMK
CAS :<p>Caspase-3 inhibitor. Inhibits MG 132-induced small cell lung cancer cell death in vitro.</p>Formule :C29H40FN5O11SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :685.72Chloranil
CAS :<p>Chloranil (tetrachloro-p-benzoquinone) induces inflammation and neurological dysfunction and can be used to model inflammation in mice.</p>Formule :C6Cl4O2Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :245.88DC-Y13-27
<p>Dc-y13-27, a derivative of DC-Y13, is a potent YTHDF2 inhibitor (KD: 37.9 μM).</p>Formule :C14H10N2O2SDegré de pureté :99.75%Couleur et forme :SoildMasse moléculaire :270.31AVJ16
CAS :<p>AVJ16 as a member of the insulin growth factor 2 mRNA-binding protein family, binds to the mRNA of certain genes to regulate protein translation.</p>Formule :C28H27N3O4Degré de pureté :98.87% - 99.72%Couleur et forme :SolidMasse moléculaire :469.53PROTAC EGFR degrader 7
<p>Compound 13b, a potent EGFR degrader, inhibits and induces apoptosis in NSCLC cells with a DC50 of 13.2 nM.</p>Formule :C46H48N10O6Couleur et forme :SolidMasse moléculaire :836.94Bak BH3
<p>Flu-BakBH3 peptide, derived from Bak's BH3 domain, binds tightly to a crucial pocket of Bcl-XL, essential for its anti-death role.</p>Formule :C72H125N25O24Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1724.9RBN013209
CAS :<p>RBN013209 is a potent CD38 inhibitor. RBN013209 is useful in the treatment of cancer.</p>Formule :C19H24N6O3Degré de pureté :99.84%Couleur et forme :SoildMasse moléculaire :384.43Urelumab
CAS :<p>"Urelumab (BMS-66513), a humanized IgG4 mAb CD137 agonist, boosts T-cell/NK cell-mediated cytotoxicity and anti-tumor activity."</p>Degré de pureté :97.70%Couleur et forme :LiquidMasse moléculaire :145.90 kDaAntiproliferative agent-25
<p>Antiproliferative Agent-25 (Compound 3s4) is a selective PRMT5 inhibitor displaying an IC50 of 0.11 μM.</p>Formule :C20H21BrN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :401.3PB28
CAS :<p>PB28: A potent σ2 agonist (Ki 0.68 nM), σ1 antagonist (Ki 0.38 nM), with anti-tumor properties and inhibits SARS-CoV-2 interactions.</p>Formule :C24H38N2OCouleur et forme :SolidMasse moléculaire :370.581HKB99
CAS :<p>HKB99 suppresses NSCLC growth, metastasis, and overcomes erlotinib resistance.</p>Formule :C23H18N2O6SDegré de pureté :97.35% - 97.35%Couleur et forme :SolidMasse moléculaire :450.46Syringolin A
CAS :<p>Syringolin A is a useful organic compound for research related to life sciences. The catalog number is T125354 and the CAS number is 212115-96-3.</p>Formule :C24H39N5O6Couleur et forme :SolidMasse moléculaire :493.605S-Adenosyl-L-methionine
CAS :<p>S-Adenosyl-L-methionine (Ademetionine) is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder.</p>Formule :C15H22N6O5SDegré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :398.44Oxybenzone-d3
<p>Oxybenzone-d3 (Benzophenone 3-d3) is a deuterium-labeled form of Oxybenzone. Commonly used as a UV filter in tanning and skin protection products, Oxybenzone (Benzophenone 3) acts as an endocrine-disrupting chemical (EDC) that can cross both the placental and blood-brain barriers. It impairs autophagy, alters epigenetic states, and disrupts retinoid X receptor signaling in apoptotic neuronal cells.</p>Formule :C14H9D3O3Couleur et forme :SolidMasse moléculaire :231.26Se-Aspirin
CAS :<p>Se-Aspirin (Se-NSAID-8) has anticancer activity and gastroprotective effects, inhibits activation of proinflammatory and pro-survival NF-ĸB pathways, and inhibits the expression of anti-apoptotic targets downstream of NF-ĸB (e.g., Bcl-xL, Mcl-1, and survivin).Se-Aspirin induces Cell cycle arrest and activation of apoptosis accelerates ulcer healing and can be used to study pancreatic and colorectal cancer.</p>Formule :C12H12N2O3SeDegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :311.2EGFR/HER2/DHFR-IN-3
<p>EGFR/HER2/DHFR-IN-3 (compound 4c) serves as an efficacious dual inhibitor specifically targeting EGFR/HER2, exhibiting IC50 values of 0.138 μM for EGFR and 0.</p>Degré de pureté :98%Couleur et forme :Odour SolidPARP1-IN-17
<p>PARP1-IN-17 is an inhibitor that targets PARP-1 (IC50=19.24 nM ) with a slightly reduced affinity for PARP-2 (IC50=32.58 nM ) and induces apoptosis.</p>Degré de pureté :98%Couleur et forme :Odour SolidKRAS inhibitor-40
CAS :<p>KRAS inhibitor-40 (Compound 41) is an inhibitor of KRAS, disrupting the KRAS G12C-BRAF complex and suppressing the phosphorylation of the downstream ERK signaling pathway. This compound also inhibits the proliferation of tumor cells with various KRAS mutations, exhibiting antitumor activity.</p>Formule :C53H66ClF4N9O8SCouleur et forme :SolidMasse moléculaire :1100.66S-Adenosyl-L-methionine iodide
CAS :<p>S-(5'-Adenosyl)-L-methionine iodide, also known as S-Adenosyl-L-methionine iodide, is a vital methyl donor present in all living organisms [1].</p>Formule :C15H23IN6O5SCouleur et forme :SolidMasse moléculaire :526.35Enniatin A1
CAS :<p>Enniatin A1, a cyclic hexadepsipeptide from Fusarium, induces apoptosis and disrupts ERK, inhibiting ACAT (IC50: 49 μM).</p>Formule :C35H61N3O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :667.885ChoKα inhibitor-4
<p>ChoKα Inhibitor-4 is a bioisosteric agent that effectively inhibits human choline kinase α1 (HChoK α1) with an IC50 of 0.66 μM.</p>Couleur et forme :Odour SolidTNF/IFNγ-IN-1
CAS :<p>TNF/IFNγ-IN-1 (TGA) is a TNF and IFN-γ inhibitor with antioxidant and anti-inflammatory activities for neurodegenerative diseases such as Alzheimer.</p>Formule :C20H23N3O6Degré de pureté :99.39%Couleur et forme :SoildMasse moléculaire :401.41RMC-9805
CAS :<p>RMC-9805(Zoldonrasib) is a KRAS G12D inhibitor with anti-tumor and anti-proliferative activity for the study of pancreatic cancer.</p>Formule :C63H88F3N11O7Degré de pureté :98.10% - 99.51%Couleur et forme :SolidMasse moléculaire :1168.44Z-Ala-Ala-Asp-CMK
CAS :<p>Z-Ala-Ala-Asp-CMK (Z-AAD-CMK) is a selective granzyme B inhibitor that blocks granzyme B protease activity, for inflammatory diseases and tumours.</p>Formule :C19H24ClN3O7Degré de pureté :99.967%Couleur et forme :SolidMasse moléculaire :441.86Spexin TFA
<p>Spexin TFA: GAL2/GAL3 agonist (EC50: 45.7/112.2 nM), no activity at GAL1, reduces appetite, fatty acid uptake, and LH secretion; anxiolytic.</p>Formule :C76H115F3N20O21SCouleur et forme :SolidMasse moléculaire :1733.9Avotaciclib hydrochloride
<p>Avotaciclib hydrochloride, a CDK1 inhibitor, is the hydrochloride salt of Avotaciclib and exhibits potential therapeutic use in specific malignancies, including</p>Formule :C13H12ClN7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :317.732-aminobenzo[d]thiazol-6-ol
CAS :<p>2-aminobenzo[d]thiazol-6-ol: antimicrobial, antioxidant, anticancer; may trigger cancer cell apoptosis.</p>Formule :C7H6N2OSDegré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :166.2Thalidomide-NH-PEG7
<p>Thalidomide-NH-PEG7, a chemical for creating PROTAC iRucaparib-AP6, selectively degrades PARP1 and is used in ADCs.</p>Formule :C27H39N3O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :581.61Annonacin
CAS :<p>Annonacin is a cytotoxic acetogenin in Graviola leaf extract; it blocks mitochondrial complex and inhibits NKA/SERCA ATPase pumps.</p>Formule :C35H64O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :596.88HDAC6-IN-16
<p>HDAC6-IN-16 (compound 5c), a quinazolin-4(3H)-one-based inhibitor of histone deacetylase 6 (HDAC6), demonstrates an anticancer effect by inhibiting colony</p>Formule :C23H19N3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :417.48Oxythiamine
CAS :<p>Oxythiamine (Hydroxythiamin) is a TK inhibitor that inhibits cancer cell proliferation, induces cell cycle arrest, and induces apoptosis.</p>Formule :C12H16N3O2SDegré de pureté :96.14% - 99.51%Couleur et forme :SolidMasse moléculaire :266.34Emavusertib hydrochloride
CAS :<p>Emavusertib (CA-4948) hydrochloride, a selective and potent IRAK4/FLT3 inhibitor, is designed for oral administration. It achieves an IC 50 of 57 nM against IRAK4 in a FRET kinase assay and demonstrates anti-tumor activity [1] [2] [3].</p>Formule :C24H26ClN7O5Couleur et forme :SolidMasse moléculaire :527.96Leucettamol A
CAS :<p>Leucettamol A, from Leucetta microraphis, blocks LTB4 receptor and prevents Ubc13-Uev1A complex formation.</p>Formule :C30H52N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :472.7582-Acetamidophenol
CAS :<p>2-Acetamidophenol (Orthocetamol) has analgesic and antipyretic effects. 2-Acetamidophenol is an isomer of Paracetamol (4-acetamidophenol).</p>Formule :C8H9NO2Degré de pureté :>99.99%Couleur et forme :Light Brown PowderMasse moléculaire :151.16Ac-IEPD-AFC
CAS :<p>Ac-IEPD-AFC (IEPD) is a fluorescent substrate for granzyme B and can be used to measure granzyme B activity.</p>Formule :C32H38F3N5O11Degré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :725.67PD0166285 dihydrochloride
CAS :<p>PD-166285 is an effective and broadly active inhibitor of protein tyrosine kinase.</p>Formule :C26H29Cl4N5O2Couleur et forme :SolidMasse moléculaire :585.35KB03-SLF
CAS :<p>KB03-SLF is a protease with the capability to target specific proteins and regulate intracellular protein levels by inducing protein degradation. This mechanism renders KB03-SLF potentially valuable in the suppression of related diseases.</p>Formule :C50H63ClF3N5O12Couleur et forme :SolidMasse moléculaire :1018.51Thalidomide 4'-oxyacetamide-alkyl-C2-amine HCl
CAS :<p>Thalidomide 4'-oxyacetamide-alkyl-C2-amine HCl is an E3 ligase ligand-linker conjugate containing the E3 ubiquitin ligase cereblon (CRBN) and linker.</p>Formule :C17H19ClN4O6Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :410.81Apoptosis inducer 33
<p>Apoptosisinducer 33 (compound H2) is a hydrazone derivative. It exhibits antioxidant and antimicrobial properties, capable of inhibiting the growth of Staphylococcus aureus, Escherichia coli, and Candida albicans. Additionally, Apoptosisinducer 33 can suppress tumor cell proliferation and induce apoptosis (apoptosis), making it useful for tumor research.</p>Formule :C16H13N3O2Couleur et forme :SolidMasse moléculaire :279.293JAK/HDAC-IN-2
<p>JAK/HDAC-IN-2, a potent 2-amino-4-phenylaminopyrimidine dual-target inhibitor, effectively suppresses JAK1/2 and HDAC3/6 at nanomolar concentrations.</p>Formule :C28H38N6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :570.74-Epianhydrotetracycline hydrochloride
CAS :<p>EATC, a tetracycline byproduct, combats Pseudomonas to E. coli with MIC50s of 0.75-16 mg/L.</p>Formule :C22H23ClN2O7Couleur et forme :SolidMasse moléculaire :462.88(R)-JAK2/STAT3-IN-10a
CAS :<p>(R)-JAK2/STAT3-IN-10a is the R-isomer of JAK2/STAT3-IN-1.JAK2/STAT3-IN-1 is a structural domain inhibitor of GP130 D1 with antitumor activity.</p>Formule :C34H35BrF3N5O2Degré de pureté :97.99%Couleur et forme :SoildMasse moléculaire :682.57Methyl-4-oxoretinoate
CAS :<p>Methyl-4-oxoretinoate is a synthetic retinoid with anticancer properties, used for skin conditions and potential ocular treatments.</p>Formule :C21H28O3Degré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :328.454-N-Nonyloxyphenol
CAS :<p>4-N-Nonyloxyphenol, kaolinite nanotube photosensitizer, degrades phenolic pesticides, and disrupts endocrine.</p>Formule :C15H24O2Degré de pureté :99.94%Couleur et forme :SoildMasse moléculaire :236.35Conophylline
CAS :<p>Conophylline, an alkaloid from Ervatamia microphylla, induces pancreatic cell differentiation and apoptosis, and suppresses HSC.</p>Formule :C44H50N4O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :794.892,2'-Dihydroxy chalcone
CAS :<p>2,2'-Dihydroxy chalcone inhibits β-glucuronidase (IC50=1.6 μM) and lysozyme (IC50=1.4 μM), and fights E. coli, S. fowleri, S. albicans, S. aureus.</p>Formule :C15H12O3Degré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :240.25
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