Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5592 produits trouvés pour "Apoptose"
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Perillyl alcohol
CAS :<p>Perillyl Alcohol, a monoterpene with antitumor properties, inhibits protein activation blocking cancer cell growth.</p>Formule :C10H16ODegré de pureté :97.36%Couleur et forme :SolidMasse moléculaire :152.23Diclofenac Potassium
CAS :<p>Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.</p>Formule :C14H10Cl2KNO2Degré de pureté :99.51%Couleur et forme :White To Yellowish Crystalline PowderMasse moléculaire :334.24PS210
CAS :<p>PS210 selectively activates PDK1 (Kd: 3 μM), doesn't affect PDK1 downstream kinases. Prodrug PS423 inhibits PDK1-mediated S6K phosphorylation.</p>Formule :C19H15F3O5Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :380.31Thalidomide-O-amido-PEG2-C2-NH2 TFA
CAS :<p>Thalidomide-based E3 ligase ligand-linker for PROTAC with PEG2 bridge; cereblon-targeted.</p>Formule :C23H27F3N4O10Degré de pureté :95.74% - 99%Couleur et forme :SolidMasse moléculaire :576.48JNJ-7706621
CAS :<p>JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.</p>Formule :C15H12F2N6O3SDegré de pureté :99.1% - 99.85%Couleur et forme :SolidMasse moléculaire :394.36GSK2334470
CAS :<p>GSK2334470 is a novel PDK1 inhibitor (IC50: ~10 nM, in a cell-free assay), with no inhibitory at other close related AGC-kinases.</p>Formule :C25H34N8ODegré de pureté :99.57% - 99.87%Couleur et forme :SolidMasse moléculaire :462.59Nocodazole
CAS :<p>Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.</p>Formule :C14H11N3O3SDegré de pureté :98% - 99.91%Couleur et forme :Physical Description White Powder (Ntp 1992)Masse moléculaire :301.32YUM70
CAS :<p>YUM70 inhibits GRP78 (IC50: 1.5μM), inducing ER stress and apoptosis in pancreatic cancer.</p>Formule :C21H19ClN2O4Degré de pureté :97.25%Couleur et forme :SolidMasse moléculaire :398.84Isoliensinine
CAS :<p>Isoliensinine (Isoliensinin) is a natural product, a bisbenzylisoquinoline alkaloid. Isoliensinine has antitumor and antioxidant effects. Cost effective and quality assured.</p>Formule :C37H42N2O6Degré de pureté :98.53% - 99.79%Couleur et forme :SolidMasse moléculaire :610.74BDA-366
CAS :<p>BDA-366, a potent Bcl2 antagonist, selectively binds the Bcl2-BH4 domain with high affinity (Ki = 3.3 nM), inducing a conformational change that nullifies its</p>Formule :C24H29N3O4Degré de pureté :98.61%Couleur et forme :SoildMasse moléculaire :423.5MG-132
CAS :<p>MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor, cell-permeable and reversible,an autophagy activator, induces apoptosis. High-Quality, Low-Cost!</p>Formule :C26H41N3O5Degré de pureté :95% - 99.99%Couleur et forme :White To Off-White PowderMasse moléculaire :475.62PYR-41
CAS :<p>PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.</p>Formule :C17H13N3O7Degré de pureté :98.25%Couleur et forme :SolidMasse moléculaire :371.3IMT1
CAS :<p>IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.</p>Formule :C21H21NO4Degré de pureté :98.07% - 98.14%Couleur et forme :SolidMasse moléculaire :351.4Cystamine dihydrochloride
CAS :<p>Cystamine dihydrochloride is a radiation-protective agent. It also protects against carbon tetrachloride liver damage.</p>Formule :C4H14Cl2N2S2Degré de pureté :98.91% - 99.81%Couleur et forme :White PowderMasse moléculaire :225.19Dictamine
CAS :<p>Dictamine (Dectamine) shows anticholinesterase, anti-inflammatory, mutagenic, and has antimicrobial activity against bacteria and fungi.</p>Formule :C12H9NO2Degré de pureté :99.72% - 99.889%Couleur et forme :SolidMasse moléculaire :199.21WP1066
CAS :<p>WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.</p>Formule :C17H14BrN3ODegré de pureté :98.92% - 99.73%Couleur et forme :SolidMasse moléculaire :356.22Lanreotide acetate
CAS :<p>Lanreotide acetate (BIM 23014 acetate) is a somatostatin analogue with antineoplastic activity, used for carcinoid syndrome</p>Formule :C56H73N11O12S2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :1156.39PD184161
CAS :<p>PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) in a time- and concentration-dependent manner[1].</p>Formule :C17H13BrClF2IN2O2Degré de pureté :99.40%Couleur et forme :SolidMasse moléculaire :557.56Epoxomicin
CAS :<p>Epoxomicin, a selective proteasome inhibitor, chiefly blocks CH-L activity, mildly affecting T-L and PGPH at lower rates.</p>Formule :C28H50N4O7Degré de pureté :98.65% - 98.86%Couleur et forme :White To Off-White SolidMasse moléculaire :554.72KX2-361
CAS :<p>KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma</p>Formule :C24H24FN3O2Degré de pureté :99.64% - 99.68%Couleur et forme :SolidMasse moléculaire :405.463-O-Acetyloleanolic acid
CAS :<p>3-O-acetyloleanolic acid dose-dependently inhibited the viability of HCT-116 cells.</p>Formule :C32H50O4Degré de pureté :98% - 99.57%Couleur et forme :SolidMasse moléculaire :498.74Masitinib
CAS :<p>Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.</p>Formule :C28H30N6OSDegré de pureté :97.56% - >99.99%Couleur et forme :SolidMasse moléculaire :498.64RSL3
CAS :<p>View and buy RSL3 from TargetMol.RSL3 is a VDAC-independent ferroptosis activator.Cited in 10 publications.</p>Formule :C23H21ClN2O5Degré de pureté :98% - 99.96%Couleur et forme :SolidMasse moléculaire :440.88Fipronil
CAS :<p>Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family.</p>Formule :C12H4Cl2F6N4OSDegré de pureté :97.21%Couleur et forme :Solid PowderMasse moléculaire :437.15Z-VAD-FMK
CAS :<p>Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does not</p>Formule :C21H28FN3O7Degré de pureté :98.24% - 99.79%Couleur et forme :SolidMasse moléculaire :453.46(20S)-Protopanaxatriol
CAS :<p>(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid</p>Formule :C30H52O4Degré de pureté :95% - 99%Couleur et forme :SolidMasse moléculaire :476.73Ralimetinib dimesylate
CAS :<p>Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.</p>Formule :C24H29FN6·2CH4O3SDegré de pureté :98% - 99.38%Couleur et forme :SolidMasse moléculaire :612.74Schisandrin C
CAS :<p>Schisandrin C (Wuweizisu-C) is a phytochemical lignan isolated from Schizandra chinensis Baill; shows anticancer-effects in human leukemia U937 cells.</p>Formule :C22H24O6Degré de pureté :99.44% - 99.56%Couleur et forme :SolidMasse moléculaire :384.42Pomolic acid
CAS :<p>Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-</p>Formule :C30H48O4Degré de pureté :96.84% - 99.79%Couleur et forme :SolidMasse moléculaire :472.7Gemcitabine hydrochloride
CAS :<p>Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.</p>Formule :C9H11F2N3O4·HClDegré de pureté :99.28% - 99.98%Couleur et forme :White Crystalline Granular OdorlessMasse moléculaire :299.66AZ960
CAS :<p>AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).</p>Formule :C18H16F2N6Degré de pureté :96.02% - 98.51%Couleur et forme :SolidMasse moléculaire :354.36Astaxanthin
CAS :<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Formule :C40H52O4Degré de pureté :95.1% - 99.79%Couleur et forme :Needles From Acetone/Light Petroleum SolidMasse moléculaire :596.84Crebanine
CAS :<p>Crebanine mitigates arrhythmias, increases aconitine tolerance in rats, lacks effect on ouabain-induce arrhythmias, and shows anti-cancer properties.</p>Formule :C20H21NO4Degré de pureté :99.17% - 99.77%Couleur et forme :SolidMasse moléculaire :339.39W-7 hydrochloride
CAS :<p>W-7 hydrochloride (W-7 HCl), a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochloride</p>Formule :C16H22Cl2N2O2SDegré de pureté :99.63%Couleur et forme :White Crystalline SolidMasse moléculaire :377.32OTS964 hydrochloride
CAS :<p>OTS964 hydrochloride (OTS964) is a potent and selective TOPK inhibitor with potential anticancer activity.</p>Formule :C23H24N2O2S·HClDegré de pureté :96.5% - 98.03%Couleur et forme :SolidMasse moléculaire :428.97DEL-22379
CAS :<p>DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ～0.5 μM.</p>Formule :C26H28N4O3Degré de pureté :99.3% - 99.53%Couleur et forme :SolidMasse moléculaire :444.53Ivachtin
CAS :<p>Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remaining</p>Formule :C20H21N3O7SDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :447.46WM-3835
CAS :<p>WM-3835, a specific KAT7 inhibitor, potently halts OS cell growth, migration, and induces apoptosis.</p>Formule :C20H17FN2O4SDegré de pureté :97.78% - 99.36%Couleur et forme :SolidMasse moléculaire :400.42Gomisin N
CAS :<p>Gomisin N from Schisandra chinensis offers sedative effects, allergy relief, and cancer cell inhibition/apoptosis.</p>Formule :C23H28O6Degré de pureté :99.97% - >99.99%Couleur et forme :SolidMasse moléculaire :400.46Cilengitide
CAS :<p>Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.</p>Formule :C27H40N8O7Degré de pureté :98% - 99.8%Couleur et forme :SolidMasse moléculaire :588.66Taurodeoxycholic acid sodium hydrate
CAS :<p>Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.</p>Formule :C26H46NNaO7SDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :539.70Afimetoran
CAS :<p>Afimetoran (BMS-986256) is a toll-like receptor antagonist. Afimetoran can be used in the research of inflammatory and autoimmune diseases.</p>Formule :C26H32N6ODegré de pureté :99.81% - 99.94%Couleur et forme :SolidMasse moléculaire :444.57Rabeprazole sodium
CAS :<p>Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.</p>Formule :C18H20N3NaO3SDegré de pureté :98% - 99.912%Couleur et forme :White Or Off White Crystalline PowderMasse moléculaire :381.42BRD3308
CAS :<p>BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK.</p>Formule :C15H14FN3O2Degré de pureté :97%Couleur et forme :SolidMasse moléculaire :287.29(Rac)-Antineoplaston A10
CAS :<p>Antineoplaston A10 is the first identified human antineoplaston, naturally occurring with anti-proliferative properties.</p>Formule :C13H14N2O3Degré de pureté :98.41%Couleur et forme :SolidMasse moléculaire :246.26Venetoclax
CAS :<p>Venetoclax (ABT-199) is a selective inhibitor of Bcl-2 (Ki < 0.010 nM), binding over 3 orders of magnitude less avidly to Bcl-xL, and Bcl-W (Kis = 48/245 nM).</p>Formule :C45H50ClN7O7SDegré de pureté :98.00% - 99.97%Couleur et forme :SolidMasse moléculaire :868.44α-Thujone
CAS :<p>α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.</p>Formule :C10H16ODegré de pureté :97.02% - 98.41%Couleur et forme :Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Masse moléculaire :152.23Triglycidyl isocyanurate
CAS :<p>Triglycidyl isocyanurate (Teroxirone) is a cancer-research chemical with DNA-altering properties, also used in metal finishing.</p>Formule :C12H15N3O6Degré de pureté :99.01%Couleur et forme :White Solid ParticulatesMasse moléculaire :297.26AZD1208 hydrochloride
CAS :<p>AZD1208 hydrochloride is a highly selective, potent and orally active PIM inhibitor.</p>Formule :C21H22ClN3O2SCouleur et forme :SolidMasse moléculaire :415.94DMU-212
CAS :<p>DMU-212, a Resveratrol derivative, has antimitotic, antiproliferative, antioxidant properties; induces apoptosis via ERK1/2.</p>Formule :C18H20O4Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :300.35
