Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(134 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(93 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6223 produits trouvés pour "Apoptose"
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IMMH 010 maleate
CAS :IMMH 010 maleate (YPD-30 maleate) is a programmed cell death ligand 1 inhibitor used in the study of neurological disorders and advanced malignant solid tumors.Formule :C36H36BrClN2O9Couleur et forme :SoildMasse moléculaire :756.04RIPK1-IN-27
RIPK1-IN-27 (compound 19) is an inhibitor of RIPK1.Formule :C27H28N4O3Couleur et forme :SolidMasse moléculaire :456.54Liensinine Perchlorate
CAS :Liensinine is the active constituent of plumula nelambinis with anti-hypertension.
Formule :C37H43ClN2O10Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :711.2LSD1-IN-24
CAS :LSD1-IN-24 is a selective and potent LSD1 inhibitor with an IC50 value of 0.247 μM.LSD1-IN-24 induces PD-L1 expression and enhances the T cell killing responseFormule :C18H20N2OSDegré de pureté :99.61%Couleur et forme :SoildMasse moléculaire :312.43Ref: TM-T67871
1mg34,00€5mg77,00€1mL*10mM (DMSO)84,00€10mg110,00€25mg212,00€50mg349,00€100mg532,00€200mg705,00€COG-1410 acetate
COG-1410 acetate is an apolipoprotein E-derived peptide and can be used in studies about neurological diseases.Formule :C66H125N21O16Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :1468.83W1131 TFA
W1131 TFA is a STAT3 inhibitor and ferroptosis inducer that regulates the IL6-JAK-STAT3 and ferroptosis pathways,gastric cancer.Formule :C25H20F3N5O6Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :543.45Ref: TM-T80847
1mL*10mM (DMSO)À demander1mg92,00€5mg188,00€10mg311,00€25mg628,00€50mg1.008,00€100mg1.596,00€YL-5092
CAS :YL-5092, YTHDC1 inhibitor (IC50=7.4 nM), induces G0/G1 arrest and apoptosis, used for acute myeloid leukemia (AML).Formule :C22H14F3N3O2SCouleur et forme :SolidMasse moléculaire :441.43YT117R
YT117R is a PROTAC that targets degradation of FKBP12 and BRD4.Formule :C50H52ClN9O7SCouleur et forme :SolidMasse moléculaire :958.52Ac-DNLD-CHO
CAS :Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is an inhibitor of Caspase-3/7, exhibiting IC50 values of 9.89 nM and 245 nM, and approximate Ki values of 0.68 nM and 55.7Formule :C20H31N5O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :501.49RIPK2/3-IN-1
RIPK2/3-IN-1 is a potent inhibitor of both RIPK2 and RIPK3 kinases, exhibiting IC50 values of 3 nM for RIPK2 and 117 nM for RIPK3.Formule :C24H16N4O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :456.54AFMK
CAS :AFMK (Formyl-N-acetyl-5-methoxykynurenamine) is an active metabolite of Melatonin with antioxidant and free radical scavenging activity.Formule :C13H16N2O4Degré de pureté :98.34% - 99.81%Couleur et forme :SolidMasse moléculaire :264.28PTD10
CAS :PTD10 is a BTK-targeting PROTAC degradator, induces apoptosis via caspase-dependent and mitochondrial pathways, B-cell dysregulation.Formule :C49H51N11O8Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :922.99MEDI-7352
MEDI-7352 is a human bispecific antibody targeting NGF/bNGF and TNF. It can be utilized in research focused on osteoarthritis (OA) pain.Couleur et forme :Odour LiquidAc-AAVALLPAVLLALLAP-YVAD-CHO
CAS :Ac-AAVALLPAVLLALLAP-YVAD-CHO is a cell-permeable inhibitor of caspase-1 exhibiting antitumor activity [1].Formule :C97H160N20O24Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1990.43Zeluvalimab
CAS :Zeluvalimab (AMG-404) is a monoclonal antibody designed to target the PD-1 receptor, and is utilized in cancer research [1].Couleur et forme :LiquidAtacicept
CAS :Atacicept (TACI-Ig) is a homodimeric fusion protein that inhibits B cell stimulation.Degré de pureté :97.9% (SDS-PAGE); 98.7% (SEC-HPLC) - 97.9% (SDS-PAGE); 98.7% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :35.36 kDaBalstilimab
CAS :Balstilimab (AGEN2034) is a fully human monoclonal IgG4 antibody against PD-1 [1] .Couleur et forme :LiquidAnti-Mouse CD44 Antibody (IM7)
Anti-Mouse CD44 Antibody (IM7) is a monoclonal antibody targeting CD44 in mice.Degré de pureté :99%Couleur et forme :Odour LiquidMasse moléculaire :150 kDaFinotonlimab
Finotonlimab (SCT-I10A), a humanized IgG PD-1 monoclonal antibody, shows potential in the research of solid tumors or lymphomas [1].Couleur et forme :Odour LiquidOnercept
CAS :Onercept, a recombinant soluble form of the human tumor necrosis factor-alpha (TNF-α) p55 receptor, is utilized in the study of Crohn's disease [1].Couleur et forme :LiquidManelimab
CAS :Manelimab is a monoclonal antibody that inhibits programmed death-ligand 1 ( PD-L1 ) [1] .Couleur et forme :LiquidLenercept
CAS :Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].Couleur et forme :LiquidLatikafusp
CAS :Latikafusp (AMG 256) is a fusion protein that is a PD-1 blocker and IL-21R agonist with antitumor activity.Degré de pureté :97.1% (SDS-PAGE); 97.4% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.4% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :159.55 kDaEfaprinermin alfa
CAS :Efaprimermin alfa (OMP-336B11) is a human monoclonal antibody that targets TNFRSF18, and functions as a GITR ligand-Fc fusion protein [1].Couleur et forme :LiquidPamrevlumab
CAS :FG-3019 (Pamrevlumab), a human antibody, targets CTGF, potentially treating idiopathic pulmonary fibrosis.Degré de pureté :100% (SEC-HPLC) - >95.0% (SDS-PAGE)Couleur et forme :LiquidMasse moléculaire :150 kDaIzuralimab
CAS :Izuralimab is a bispecific IgG1 antibody that targets both the inducible T-cell costimulator (ICOS/CD278) and PD-1 [1].Couleur et forme :LiquidAtibuclimab
CAS :Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region.Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :145.28 kDaAnti-Mouse PD-L1/B7-H1 (LALA-PG) Antibody (10F.9G2)
Anti-Mouse PD-L1/B7-H1 (LALA-PG) Antibody (10F.9G2) is an IgG2a, κ antibody inhibitor derived from mice, specifically targeting and inhibiting mouse PD-L1/B7-H1.Couleur et forme :Odour LiquidAnti-Mouse PD-1 Antibody (RMP1-14)
Anti-Mouse PD-1 Antibody (RMP1-14) is an IgG2a antibody inhibitor against mouse PD-1 and can block PD-1/PD-L1 signaling. High-Quality, Low-Cost!Degré de pureté :14.68mg/ml - >95%Couleur et forme :LiquidMasse moléculaire :147.57 kDaDiethanolamine hydrochloride
CAS :Diethanolamine hydrochloride is HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4) and pregnane X receptor (PXR), p53 Estrogen receptor.Formule :C4H12ClNO2Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :141.6δ-secretase inhibitor 11
CAS :δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.Formule :C10H12N4O2Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :220.23Lipustobart
CAS :Lipustobart is an IgG4-kappa humanized monoclonal antibody targeting PDCD1 (programmed cell death 1, PD1, PD-1, CD279), with immunostimulant and antineoplasticDegré de pureté :98%Couleur et forme :LiquidTulinercept
CAS :Tulinercept (OPRX-106), a monoclonal antibody, may be utilized in a range of biochemical research applications [1].Couleur et forme :LiquidZigakibart
CAS :Zigakibart (BION-1301) is a humanized monoclonal antibody targeting TNFSF13 with anti-inflammatory activity for the study of immunoglobulin A nephropathy (IgAN)Degré de pureté :95.8% (SDS-PAGE); 99.8% (SEC-HPLC) - 95.8% (SDS-PAGE); 99.8% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.03 kDaBMS-986156
BMS-986156 is a fully humanized IgG1 agonist monoclonal antibody that targets the glucocorticoid-induced tumor necrosis factor receptor-related protein (GITR). It binds to GITR and enhances the activation of T effector cells while deactivating T regulatory cells. BMS-986156 is applicable for research in advanced solid tumors.Giloralimab
CAS :Giloralimab (ABBV-927) is a antibody targeting CD40 with anticancer activity for the study of triple-negative breast cancer and non-small cell lung cancer.Degré de pureté :95.6% (SDS-PAGE); 95.1% (SEC-HPLC) - 95.6% (SDS-PAGE); 95.1% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :146.34 kDaDazodalibep
CAS :Dazodalibep (MEDI 4920; VIB 4920) is a monoclonal antibody that specifically targets CD40LG/TNFSF5 and is fused to human serum albumin (ALB/HSA) [1].Couleur et forme :LiquidSU11652
CAS :SU11652 is an effective and competitive receptor tyrosine kinase (RTK) inhibitor, including VEGFR, FGFR, PDGFR, and Kit.Formule :C22H27ClN4O2Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :414.93VK3-OCH3
CAS :Formule :C14H14O3SDegré de pureté :>98.0%(HPLC)Couleur et forme :Light yellow to Yellow to Orange powder to crystalMasse moléculaire :262.32Ancitabine
CAS :Ancitabine is an antitumour drug that improves Hailey-Hailey disease-related phenotypes in yeast models. inhibits DNA synthesis, acute leukaemia.Formule :C9H11N3O4Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :225.2RRD-251
CAS :RRD-251 is an Rb-Raf-1 interaction inhibitor that induces apoptosis in metastatic melanoma cells and synergizes with dacarbazine[1].Formule :C8H9Cl3N2SCouleur et forme :SolidMasse moléculaire :271.59Ref: TM-T60475
10mgÀ demander25mgÀ demander50mgÀ demander100mgÀ demander1mL*10mM (DMSO)À demander5mg46,00€AZD5582
CAS :AZD5582 is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. It induces apoptosis.Formule :C58H78N8O8Degré de pureté :98.75%Couleur et forme :SolidMasse moléculaire :1015.29Galiximab
CAS :Melrilimab (GSK 3772847) is an IgG antibody targeting IL-33R with high affinity for IL1RL1/ST2/DER4/FIT-1 and can be used in asthma research.Degré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :145.24 kDaThalidomide-O-amido-PEG4-C2-NH2 hydrochloride
CAS :Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and aFormule :C25H35ClN4O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :587.02KS100
CAS :KS100 inhibits ALDH1A1, ALDH2, ALDH3A1, boosts ROS, triggers apoptosis, and has anti-cancer properties.Formule :C17H14Br3N3O2SDegré de pureté :97.05%Couleur et forme :SolidMasse moléculaire :564.09Nafamostat
CAS :Nafamostat is a synthetic serine protease inhibitor and an anticoagulant used in haemodialysis. It induces apoptosis, inhibiting SARS-CoV-2 and COVID-19.Formule :C19H17N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :347.37Isoalantolactone
CAS :Formule :C15H20O2Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :232.32Bax inhibitor peptide V5
CAS :Bax inhibitor peptide V5 (BIP-V5) is a Bax-mediated apoptosis inhibitor with anticancer activity.Formule :C27H50N6O6SCouleur et forme :SolidMasse moléculaire :586.791-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)uracil
CAS :1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil is a Nucleoside, fluoro-modified nucleoside; Arabino-nucleosidde.Formule :C9H11FN2O5Degré de pureté :98.36%Couleur et forme :SolidMasse moléculaire :246.19
