Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(127 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(90 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6170 produits trouvés pour "Apoptose"
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2'-Aminoacetophenone
CAS :Compound Fr14273 is a natural product for research related to life sciences. The catalog number is Fr14273 and the CAS number is 551-93-9.Formule :C8H9NODegré de pureté :99.88%Couleur et forme :Pale Yellow Solid Solid CrystallineMasse moléculaire :135.17Phenoxyethanol (Standard)
CAS :Phenoxyethanol (Standard) is the standard substance of Phenoxyethanol, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Phenoxyethanol (NSC-1864) is germicidal. It often used together with quaternary ammonium compounds.Formule :C8H10O2Couleur et forme :Clear To Practically Clear Colourless LiquidMasse moléculaire :138.16Ancitabine
CAS :Ancitabine is an antitumour drug that improves Hailey-Hailey disease-related phenotypes in yeast models. inhibits DNA synthesis, acute leukaemia.Formule :C9H11N3O4Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :225.2Prexasertib dimesylate
CAS :Prexasertib dimesylate is a selective CHK1 inhibitor with K i 0.9 nM, blocks CHK2 & RSK1, induces DNA breakage, and has potent anti-tumor effects.Formule :C20H27N7O8S2Couleur et forme :SolidMasse moléculaire :557.6Acetic acid, 2-[[4-[[[4-(1,1-dimethylethyl)phenyl]sulfonyl]amino]-1-hydroxy-2-naphthalenyl]thio]-
CAS :KPT-6566 is a covalent PIN1 inhibitor that selectively targets cancer cells by a dual mechanism of action.Formule :C22H23NO5S2Couleur et forme :SolidMasse moléculaire :445.55Terfenadine (Standard)
CAS :Terfenadine (Standard) is the standard substance of Terfenadine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Terfenadine ((±)-Terfenadine) is a prodrug that is metabolized by intestinal CYP3A4 to the active form fexofenadine, a selective histamine H1-receptor antagonist with antihistaminic and non-sedative effects.Formule :C32H41NO2Masse moléculaire :471.67Alternariol (Standard)
CAS :Alternariol (Standard) is the standard substance of Alternariol, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Alternariol (AOH), a mycotoxin synthesized by Alternaria species, displays numerous therapeutic and biological effects, including phytotoxic, cytotoxic, anti-HIV, anti-cancer, and anti-microbial properties. It functions by inhibiting the catalytic activity of topoisomerase I and II enzymes.Formule :C14H10O5Couleur et forme :SolidMasse moléculaire :258.23Furazolidone (Standard)
CAS :Furazolidone (Standard) is the standard substance of Furazolidone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Furazolidone (Furoxone), a nitrofuran derivative, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM. It is antibacterial and antiprotozoal activity,Formule :C8H7N3O5Masse moléculaire :225.16Taltirelin
CAS :Taltirelin (TA-0910) is at thyrotropin-releasing hormone receptor (TRH-R) superagonist (IC50 of 910 nM and EC50 of 36 nM for stimulating an increase inFormule :C17H23N7O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :405.41BAY 11-7082
CAS :Formule :C10H9NO2SDegré de pureté :>98.0%(HPLC)(N)Couleur et forme :White to Almost white powder to crystalMasse moléculaire :207.25RKI-1447 dihydrochloride
CAS :RKI 1447 dihydrochloride: selective ROCK inhibitor, inhibits colorectal cancer growth, promotes apoptosis (ROCK1 IC50=14.5 nM, ROCK2 IC50=6.2 nM).Formule :C16H16Cl2N4O2SCouleur et forme :SolidMasse moléculaire :399.29Pevonedistat hydrochloride
CAS :Pevonedistat(MLN4924) hydrochloride is a NEDD8-activating enzyme inhibitor that induces apoptosis and can be used in the study of acute myeloid leukemias.Formule :C21H26ClN5O4SDegré de pureté :98.44% - 99.19%Couleur et forme :SolidMasse moléculaire :479.98Alisol B 23-Acetate
CAS :Formule :C32H50O5Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :514.75NSC 80467
CAS :NSC 80467 inhibits survivin, targets DNA synthesis, induces γH2AX, and pKAP1 markers of DNA damage.Formule :C24H22BrN3O5Degré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :512.35OTS193320
CAS :OTS193320, an imidazo[1,2-a]pyridine, inhibits SUV39H2, reduces H3K9me3, and induces apoptosis in breast cancer; enhances DOX effects.Formule :C28H30ClN5O4Couleur et forme :SolidMasse moléculaire :536.02Lestaurtinib
CAS :Lestaurtinib (CEP 701) is a FLT3 inhibitor that inhibits the phosphorylation of RPTKs and can be used to study leukemia.Formule :C26H21N3O4Degré de pureté :99.17%Couleur et forme :Off-White SolidMasse moléculaire :439.46Isoalantolactone
CAS :Formule :C15H20O2Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :232.32Rapamycin-d3
CAS :Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific inhibitor of mTOR(IC50 of 0.1 nM in HEK293 cells).Formule :C51H79NO13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :917.19CuATSM
CAS :Cu/Zn-SOD1 enzyme scavenges radicals; mutations cause ALS. Cu-ATSM, crossing blood-brain barrier, targets hypoxic tissue, may aid ALS mice.Formule :C8H14CuN6S2Couleur et forme :SolidMasse moléculaire :321.92Devazepide
CAS :Devazepide is a competitive, selective, orally available non-peptide CCK1 receptor antagonist that inhibits proliferation, induce apoptosis.Formule :C25H20N4O2Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :408.45CCW16
CAS :CCW16 is a covalent E3 ubiquitin ligase RNF4 ligand, cysteine reactivity, inducing ferroptosis in AML cells by activating ROS signalling.Formule :C22H20ClNO3Degré de pureté :97%Couleur et forme :SolidMasse moléculaire :381.85BCL6-IN-5
CAS :BCL6-IN-5 is a highly effective inhibitor of BCL6. It exhibits a pIC50 value of 5.82.Formule :C17H19Cl2N5O2Couleur et forme :SolidMasse moléculaire :396.27PBOX 6
CAS :PBOX 6 is a pyrrolo-1,5-benzoxazepine (PBOX) compound with anticancer and antitumor activity that inhibits the growth of breast cancer cells.Formule :C25H20N2O3Degré de pureté :98.18% - 98.71%Couleur et forme :SolidMasse moléculaire :396.44Ref: TM-T16436
1mg56,00€5mg124,00€1mL*10mM (DMSO)133,00€10mg177,00€25mg295,00€50mg439,00€100mg627,00€Thalidomide-Piperazine 5-fluoride
CAS :Thalidomide-Piperazine 5-fluoride: a cereblon ligand-linked E3 ligase via PROTAC tech.Formule :C17H17FN4O4Couleur et forme :SolidMasse moléculaire :360.34SC144 hydrochloride
CAS :SC144 hydrochloride: oral gp130 inhibitor, blocks Stat3 and gene expression, triggers apoptosis in ovarian cancer cells.Formule :C16H12ClFN6OCouleur et forme :SolidMasse moléculaire :358.76p,p'-DDD
CAS :TDE is an organochlorine insecticide with slightly irritating to the skin.Formule :C14H10Cl4Couleur et forme :Colourless To Off-White CrystalsMasse moléculaire :320.03Meisoindigo
CAS :Formule :C17H12N2O2Degré de pureté :>98.0%(HPLC)Couleur et forme :Orange to Brown to Dark red powder to crystalMasse moléculaire :276.30Rutin trihydrate
CAS :Rutin trihydrate is a natural flavonoid with antioxidant, anti-inflammatory, anti-diabetic, and anti-cancer benefits, plus heart and brain protection.Formule :C27H36O19Couleur et forme :SolidMasse moléculaire :664.56Vandetanib
CAS :Formule :C22H24BrFN4O2Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :475.36(Rac)-Apremilast D5
CAS :(Rac)-Apremilast D5 is a deuterium-labeled version of the enantiomer (R)-Apremilast, also known as (R)-CC-10004, which itself is one specific form of ApremilastFormule :C22H24N2O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :465.536-Formylpterin
CAS :6-Formylpterin (Pterin-6-aldehyde) is an inhibitor of Xanthine Oxidase, which induces ROS generation and apoptosis in HL-60 cells.
Formule :C7H5N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :191.15SLF
CAS :SLF is a synthetic ligand for FKBP12 and increases Ca2+ efflux and protein synthesis.Formule :C30H40N2O6Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :524.65GSK778
CAS :GSK778 selectively inhibits BD1 bromodomains (BRD2, BRD3, BRD4, BRDT) and impedes cell growth, causing arrest and apoptosis.Formule :C30H33N5O3Degré de pureté :98.42%Couleur et forme :SolidMasse moléculaire :511.61Ref: TM-T9703
1mL*10mM (DMSO)44,00€1mg152,00€5mg295,00€10mg477,00€25mg954,00€50mg1.513,00€100mg2.097,00€Galantamin-d6
CAS :Galantamin-d6 is a deuterated compound of Galantamin.Formule :C17H15D6NO3Couleur et forme :SolidMasse moléculaire :293.39Casein Kinase inhibitor A86
CAS :Casein Kinase inhibitor A86 is a highly effective and orally bioavailable inhibitor of casein kinase 1α (CK1α) and also inhibits CDK7 (TFIIH) and CDK9 (P-TEFb). It induces apoptosis in leukemia cells, exhibiting substantial anti-leukemic effects.Formule :C18H25FN6Couleur et forme :SolidMasse moléculaire :344.438TZ9
CAS :TZ9 is a Rad6 inhibitor with anticancer activity.TZ9 inhibits Rad6B-induced ubiquitination of histone H2A.TZ9 induces cell cycle arrest and apoptosis.Formule :C17H14N6O4Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :366.33Fenobucarb
CAS :Fenobucarb is a broad-spectrum carbamate insecticide and AChE inhibitor. It exhibits neurotoxicity to zebrafish foetal development and induces muscle spasmsFormule :C12H17NO2Degré de pureté :98.80%Couleur et forme :White CrystalMasse moléculaire :207.27MX1013
CAS :MX1013, a dipeptide pan-caspase inhibitor, inhibits caspase-1, -3, -6, -7, -8, and -9.Formule :C18H23FN2O6Couleur et forme :SolidMasse moléculaire :382.39Cl-amidine TFA
CAS :Cl-amidine TFA: oral PAD inhibitor, induces cancer cell apoptosis, IC50s: PAD1 - 0.8μM, PAD3 - 6.2μM, PAD4 - 5.9μM.Formule :C16H20ClF3N4O4Couleur et forme :SolidMasse moléculaire :424.8Pyraclostrobin (Standard)
CAS :Pyraclostrobin (Standard) is the standard substance of Pyraclostrobin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Pyraclostrobin is one of the most heavily used fungicides that inhibits mitochondrial complex III of fungal and mammalian cells.Formule :C19H18ClN3O4Couleur et forme :SolidMasse moléculaire :387.82Pentagamavunon-1
CAS :PGV-1, an oral Curcumin analog, induces apoptosis by inhibiting COX-2, VEGF, and NF-κB activation.Formule :C23H24O3Couleur et forme :SolidMasse moléculaire :348.43PDK1-IN-RS2
CAS :PDK1-IN-RS2, a PIFtide mimic, selectively inhibits PDK1, blocking S6K1 activation (Kd: 9 μM).Formule :C15H9ClN2O2S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :380.893-Phenoxybenzoic acid
CAS :3-Phenoxybenzoic acid is a natural product for research related to life sciences. The catalog number is T35359 and the CAS number is 3739-38-6.Formule :C13H10O3Couleur et forme :SolidMasse moléculaire :214.22Thalidomide-5-CH2-NH2 hydrochloride
CAS :Thalidomide-5-CH2-NH2 (HCl) recruits CRBN protein, used to create PROTACs via a linker.Formule :C14H14ClN3O4Couleur et forme :SolidMasse moléculaire :323.73Diuron
CAS :Diuron is an orally active benzoylurea herbicide. Diuron inhibits the production of ATP and NADH,, ROS and cancer.Formule :C9H10Cl2N2ODegré de pureté :99.68%Couleur et forme :White Crystalline Solid Environment Immediate Steps Should Be Taken To Limit Its Spread To The Environment It Can CauseMasse moléculaire :233.10PI-103 Hydrochloride
CAS :PI-103 Hydrochloride is a dual PI3K/Akt and mTOR inhibitor exhibiting nM-level inhibition of p110α, p110β, p110δ, p110γ, DNA-PK, mTORC1, and mTORC2.Formule :C19H17ClN4O3Degré de pureté :97.07%Couleur et forme :SolidMasse moléculaire :384.82Mardepodect hydrochloride
CAS :Mardepodect hydrochloride (Mardepodect HCl) is a PDE10A inhibitor.Mardepodect hydrochloride upregulates genes encoding specific growth factors.Formule :C25H21ClN4ODegré de pureté :95.1%Couleur et forme :SolidMasse moléculaire :428.91Tacrolimus-13C-d2
CAS :Tacrolimus-13C-d2 is the 13C and deuterated compound of Tacrolimus.Formule :C44H67D2NO12Couleur et forme :SolidMasse moléculaire :807.02Rottlerin
CAS :Formule :C30H28O8Degré de pureté :>95.0%(HPLC)(qNMR)Couleur et forme :Light yellow to Brown powder to crystalMasse moléculaire :516.55Galiximab
CAS :Melrilimab (GSK 3772847) is an IgG antibody targeting IL-33R with high affinity for IL1RL1/ST2/DER4/FIT-1 and can be used in asthma research.Degré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :145.24 kDa
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