Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(127 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(90 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6170 produits trouvés pour "Apoptose"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Erdafitinib
CAS :Erdafitinib (JNJ-42756493) is a quinoxaline derivative compound, acts on FGFR1/2/3/4.Formule :C25H30N6O2Degré de pureté :97.00% - 99.36%Couleur et forme :SolidMasse moléculaire :446.54FB23-2
CAS :FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor(IC50 : 2.6 μM).Formule :C18H15Cl2N3O3Degré de pureté :97.29% - ≥95%Couleur et forme :SolidMasse moléculaire :392.24Cyclopiazonic acid
CAS :Cyclopiazonic acid (CPA) is a neurotoxic secondary metabolite (SM) made by A.Formule :C20H20N2O3Degré de pureté :99.27% - 99.80%Couleur et forme :SolidMasse moléculaire :336.38BAY 61-3606 HCl
CAS :BAY 61-3606 HCl: a reversible Syk inhibitor, halts mast cell degranulation, cytokines, and sensitizes MCF-7 cells to TRAIL-induced apoptosis.Formule :C20H19ClN6O3Couleur et forme :SolidMasse moléculaire :426.86Isoliensinine
CAS :Isoliensinine (Isoliensinin) is a natural product, a bisbenzylisoquinoline alkaloid. Isoliensinine has antitumor and antioxidant effects. Cost effective and quality assured.Formule :C37H42N2O6Degré de pureté :98.53% - 99.79%Couleur et forme :SolidMasse moléculaire :610.74Ref: TM-T5S1103
1mg34,00€5mg65,00€10mg94,00€25mg137,00€50mg193,00€100mg286,00€500mg695,00€1mL*10mM (DMSO)94,00€Ibuprofen sodium
CAS :Ibuprofen sodium is a selective COX-1 inhibitor, anti-inflammatory, and NO donor, used in pain, swelling, and cancer research.Formule :C13H17NaO2Couleur et forme :SolidMasse moléculaire :228.267K-Ras(G12C) inhibitor 12
CAS :K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).Formule :C15H17ClIN3O3Degré de pureté :97.16%Couleur et forme :SolidMasse moléculaire :449.67Avicularin
CAS :Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.Formule :C20H18O11Degré de pureté :97.02% - 99.94%Couleur et forme :White PowderMasse moléculaire :434.35Ref: TM-T6S0117
1mg55,00€5mg92,00€10mg152,00€25mg268,00€50mg395,00€100mg583,00€200mg832,00€1mL*10mM (DMSO)105,00€Baicalein monohydrate
CAS :Baicalein monohydrate blocks 12-lipoxygenase, curbs leukotrienes, lysosomal enzymes, Ca2+ dynamics, and fights arthritis.Formule :C15H12O6Couleur et forme :SolidMasse moléculaire :288.25Sodium Demethylcantharidate
CAS :Sodium Demethylcantharidate (Sodium norcantharidin) is extracted from Mylabris phqlarata pallas and has potent antitumor activity.Formule :C8H9O5·NaDegré de pureté :99.66% - ≥98%Couleur et forme :SolidMasse moléculaire :208.14Thalidomide 4'-ether-alkylC2-amine hydrochloride
CAS :Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate.Formule :C15H16ClN3O5Degré de pureté :98.56%Couleur et forme :SolidMasse moléculaire :353.76Cidofovir dihydrate
CAS :Cidofovir dihydrate: Injectable anti-CMV; suppresses CMV by inhibiting viral DNA polymerase; treats CMV retinitis in AIDS.Formule :C8H18N3O8PDegré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :315.22ML311
CAS :ML311 is a selective inhibitor of the Mcl-1/Bim interaction.Formule :C23H24F3N3ODegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :415.45DC661
CAS :DC661 is a palmitoyl-protein thioesterase 1 (PPT1) inhibitor that acts as an anti-lysosomal agent by inhibiting autophagy, demonstrating anti-cancer activity.Formule :C31H39Cl2N5Degré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :552.58Ref: TM-T5538
1mg80,00€2mg105,00€5mg188,00€10mg319,00€25mg545,00€50mg780,00€100mg1.074,00€1mL*10mM (DMSO)230,00€ML162
CAS :ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.Formule :C23H22Cl2N2O3SDegré de pureté :98.42% - 99.55%Couleur et forme :SolidMasse moléculaire :477.4Ref: TM-T8970
1mg43,00€5mg85,00€10mg110,00€25mg215,00€50mg334,00€100mg467,00€200mg672,00€1mL*10mM (DMSO)92,00€MDK83190
CAS :MDK83190 (Apoptosis Activator 2) is a potent apoptosis activator, induceing caspase-3 activation, PARP cleavage, and DNA fragmentation .Formule :C15H9Cl2NO2Degré de pureté :97.40% - 98%Couleur et forme :Orange SolidMasse moléculaire :306.14Autophagy-IN-A9
CAS :Autophagy-IN-A9 is a bioactive chemical.Formule :C15H11ClFN3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :287.72Ref: TM-T9181
2mg34,00€5mg50,00€10mg63,00€25mg110,00€50mg203,00€100mg281,00€200mg420,00€1mL*10mM (DMSO)55,00€Ricolinostat
CAS :Ricolinostat (Rocilinostat) is an orally bioavailable, specific inhibitor of histone deacetylase 6 (HDAC6) with potential antineoplastic activity.Formule :C24H27N5O3Degré de pureté :97.17% - 99.76%Couleur et forme :SolidMasse moléculaire :433.5HBX 41108
CAS :HBX 41108: non-competitive, reversible USP7 inhibitor; IC50: 424nM; blocks USP7-p53 deubiquitination; IC50: 0.8μM.Formule :C13H3ClN4ODegré de pureté :95.63%Couleur et forme :SolidMasse moléculaire :266.644-Methylsalicylic acid
CAS :4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.Formule :C8H8O3Degré de pureté :99.64%Couleur et forme :Solid Solid CrystallineMasse moléculaire :152.15TPCA-1
CAS :TPCA-1 (TPCA1) is an effective and specific IKK-2 inhibitor (IC50: 17.9 nM); shows >22-fold selectivity over IKK-1 and >550-fold selectivity over others kinasesFormule :C12H10FN3O2SDegré de pureté :95.03% - 97.86%Couleur et forme :SolidMasse moléculaire :279.29CP-461 free base
CAS :CP-461 (OSI-461) is a pde2a / 5A inhibitor, which may be used in the treatment of renal cell carcinoma, prostate cancer, and Crohn's disease.Formule :C25H21FN2OCouleur et forme :SolidMasse moléculaire :384.45B355252
CAS :B355252 prevents glutamate-induced cell death and boosts NGF's nerve growth effects.Formule :C25H24ClN3O3S2Degré de pureté :98.73% - 99.92%Couleur et forme :SolidMasse moléculaire :514.06(+)-Nortrachelogenin
CAS :(+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity.Formule :C20H22O7Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :374.38Oxysophoridine
CAS :Oxysophoridine protects against brain ischemia and heart damage through antioxidant, anti-apoptotic, and anti-inflammatory effects.Formule :C15H24N2O2Degré de pureté :98.15% - >99.99%Couleur et forme :SolidMasse moléculaire :264.36CASP3 Activator 1541
CAS :CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.Formule :C24H17N3O4Degré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :411.41Ref: TM-T8652
1mg34,00€5mg71,00€10mg105,00€25mg215,00€50mg344,00€100mg532,00€200mg740,00€1mL*10mM (DMSO)86,00€Oxaprozin potassium
CAS :Oxaprozin potassium is an oral COX inhibitor (IC50: 2.2 μM for COX-1, 36 μM for COX-2), induces apoptosis, and blocks NF-κB activation.Formule :C18H14KNO3Couleur et forme :SolidMasse moléculaire :331.412Amifostine trihydrate
CAS :Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.Formule :C5H15N2O3PS·3H2ODegré de pureté :99.71% - 99.80%Couleur et forme :SolidMasse moléculaire :268.27Chlorfenapyr
CAS :Chlorfenapyr (AC 303630) is a pyrrole insecticide and converts active substances (insecticidal activity) in insects by a multifunctional oxidaseFormule :C15H11BrClF3N2ODegré de pureté :99.33% - 99.49%Couleur et forme :Off-White To Light Brown Powder With An Halide OdorMasse moléculaire :407.61Ganoderic acid A
CAS :Ganoderic acid A fights tumors, suppresses gene regulators, induces cancer cell death, and enhances cisplatin efficacy.Formule :C30H44O7Degré de pureté :99.31% - ≥95%Couleur et forme :SolidMasse moléculaire :516.67Ref: TM-T6S1141
1mg44,00€5mg92,00€10mg152,00€25mg236,00€50mg354,00€100mg518,00€1mL*10mM (DMSO)104,00€Nerol
CAS :Nerol (Neryl alcohol) is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmiasFormule :C10H18ODegré de pureté :98.59%Couleur et forme :Colorless Oily Liquid LiquidMasse moléculaire :154.25PI-103
CAS :PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).Formule :C19H16N4O3Degré de pureté :97.79% - 99.3%Couleur et forme :SolidMasse moléculaire :348.36Poziotinib
CAS :Poziotinib (NOV120101)(NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM).Formule :C23H21Cl2FN4O3Degré de pureté :98.69% - 99.78%Couleur et forme :SolidMasse moléculaire :491.34Alemtuzumab
CAS :Alemtuzumab is a humanized monoclonal antibody against CD52 an antigen found on the surface of normal and malignant lymphocytes.
Degré de pureté :97.2% (SDS-PAGE); 96.7% (SEC-HPLC) - 98.00%Couleur et forme :LiquidMasse moléculaire :146.04 kDaCaffeic Acid Phenethyl Ester
CAS :CAPE, in propolis, blocks NF-kappa B, suppresses p70S6K/Akt pathways, and inhibits PDGF, aiding in cancer protection and immune modulation.Formule :C17H16O4Degré de pureté :99.18% - 99.35%Couleur et forme :Less Transparent Liquid Colorless Transparent LiquidMasse moléculaire :284.31Copanlisib
CAS :Copanlisib (BAY 80-6946), a PI3K inhibitor, may block tumor growth and improve cancer treatment efficacy.Formule :C23H28N8O4Degré de pureté :99% - 99.88%Couleur et forme :SolidMasse moléculaire :480.52LDC000067
CAS :LDC000067 (LDC067) is a highly specific and selective CDK9 inhibitor with an IC50 value of 44±10 nM.Formule :C18H18N4O3SDegré de pureté :98.08% - 99.07%Couleur et forme :SolidMasse moléculaire :370.43Danshensu
CAS :Danshensu (Dan shen suan A) is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.Formule :C9H10O5Degré de pureté :98.4% - 99.74%Couleur et forme :SolidMasse moléculaire :198.17R-7050
CAS :R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.Formule :C16H8ClF3N4SDegré de pureté :98.64% - 99.8%Couleur et forme :SolidMasse moléculaire :380.77Ref: TM-T4637
1mg34,00€2mg43,00€5mg63,00€10mg90,00€25mg195,00€50mg268,00€100mg439,00€200mg623,00€1mL*10mM (DMSO)71,00€VLX600
CAS :VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent.Formule :C17H15N7Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :317.35Rigosertib
CAS :Rigosertib, a multi-kinase inhibitor targeting PLK1 (IC50: 9 nM), induces apoptosis and G2/M arrest by disrupting PI3K/Akt.Formule :C21H25NO8SDegré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :451.49IACS-010759
CAS :IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain.Formule :C25H25F3N6O4SDegré de pureté :99.54% - 99.73%Couleur et forme :SolidMasse moléculaire :562.56Ref: TM-T5337
1mg49,00€2mg70,00€5mg107,00€10mg165,00€25mg334,00€50mg485,00€100mg710,00€200mg964,00€1mL*10mM (DMSO)141,00€(20S)-Protopanaxatriol
CAS :(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoidFormule :C30H52O4Degré de pureté :95% - 99%Couleur et forme :SolidMasse moléculaire :476.73Ref: TM-T2810
2mg34,00€5mg50,00€10mg66,00€25mg114,00€50mg178,00€100mg295,00€200mg442,00€1mL*10mM (DMSO)55,00€Prexasertib
CAS :Prexasertib (LY2606368) is a selective checkpoint kinase 1 (CHK1) inhibitor (Ki 0.9 nM, IC50<1 nM). antitumor activity. High-Quality, Low-Cost!Formule :C18H19N7O2Degré de pureté :97.3% - 98.23%Couleur et forme :SolidMasse moléculaire :365.39DL-Buthionine-(S,R)-sulfoximine
CAS :DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.Formule :C8H18N2O3SDegré de pureté :98% - 99.64%Couleur et forme :White Fine PowderMasse moléculaire :222.31CBL0137
CAS :CBL0137 (Curaxin 137), a metabolically stable curaxin, activates p53 (EC50: 0.37 μM) and inhibits NF-κB (EC50: 0.47 μM).Formule :C21H24N2O2Degré de pureté :99.57% - 99.68%Couleur et forme :SolidMasse moléculaire :336.43Kumatakenin
CAS :Kumatakenin can suppress >80% of the SOS-inducing activity of Trp-P-1 at <0.06 micromol/mL.Formule :C17H14O6Degré de pureté :97.44% - 98.41%Couleur et forme :SolidMasse moléculaire :314.29(Rac)-Idroxioleic acid
CAS :(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a fatty acid amide hydrolase inhibitor with anti-tumor effect.Formule :C18H34O3Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :298.46NVP-TNKS656
CAS :NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.Formule :C27H34N4O5Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :494.58Ref: TM-T3261
1mg43,00€2mg54,00€5mg84,00€10mg122,00€25mg248,00€50mg421,00€100mg617,00€1mL*10mM (DMSO)93,00€Levobupivacaine hydrochloride
CAS :Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.Formule :C18H28N2O·HClDegré de pureté :99.74%Couleur et forme :White Crystalline PowderMasse moléculaire :324.89
