Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(127 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(90 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6170 produits trouvés pour "Apoptose"
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KEA1-97
CAS :Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M).Formule :C15H9Cl2FN4Degré de pureté :97.07%Couleur et forme :SolidMasse moléculaire :335.16T0901317
CAS :T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB).Formule :C17H12F9NO3SDegré de pureté :98% - 99.64%Couleur et forme :SolidMasse moléculaire :481.33UAMC-3203
CAS :UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).Formule :C25H37N5O2SDegré de pureté :97.052% - 99.72%Couleur et forme :SolidMasse moléculaire :471.66OTS514
CAS :OTS514 (OTS514 Hydrochloride) is a potent TOPK inhibitor.Formule :C21H20N2O2SDegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :364.46Ref: TM-T4134L
1mg65,00€5mg144,00€10mg222,00€25mg394,00€50mg532,00€100mg743,00€200mg982,00€1mL*10mM (DMSO)152,00€Rebastinib
CAS :DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC,
Formule :C30H28FN7O3Degré de pureté :99.53% - 99.79%Couleur et forme :SolidMasse moléculaire :553.59Benzyl isothiocyanate
CAS :BITC, found in cruciferous veggies, exhibits anticancer, antimicrobial, and immunomodulatory effects.Formule :C8H7NSDegré de pureté :99.25% - 99.83%Couleur et forme :Clear Yellow LiquidMasse moléculaire :149.21Euscaphic acid
CAS :Euscaphic acid has anti-diabetic and anti-inflammatory effects, blocking IKK/MAPKs and NF-κB activation by disrupting TRAF6/IRAK1/TAK1 clustering.Formule :C30H48O5Degré de pureté :98.93%Couleur et forme :SolidMasse moléculaire :488.7Nocodazole
CAS :Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.Formule :C14H11N3O3SDegré de pureté :98% - 99.91%Couleur et forme :Physical Description White Powder (Ntp 1992)Masse moléculaire :301.32Ref: TM-T2802
5mg34,00€10mg52,00€25mg94,00€50mg165,00€100mg268,00€200mg399,00€500mg647,00€1mL*10mM (DMSO)38,00€Acenocoumarol
CAS :Acenocoumarol is a Vitamin K antagonist and used as an anticoagulant.Formule :C19H15NO6Degré de pureté :99.95%Couleur et forme :Crystals SolidMasse moléculaire :353.33Selonsertib
CAS :Selonsertib (GS-4997), an oral ASK1 inhibitor, may have anti-inflammatory, anti-fibrotic, and anti-cancer effects.Formule :C24H24FN7ODegré de pureté :95.04% - 99.53%Couleur et forme :SolidMasse moléculaire :445.49FR 180204
CAS :FR 180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.Formule :C18H13N7Degré de pureté :98% - 99.74%Couleur et forme :SolidMasse moléculaire :327.34Ref: TM-T1956
1mg40,00€2mg52,00€5mg81,00€10mg131,00€25mg210,00€50mg314,00€100mg470,00€1mL*10mM (DMSO)89,00€Ceftiofur
CAS :Ceftiofur is a semisynthetic antibiotic, with activity against various gram-positive/negative, anaerobic and aerobic bacteria encountered by domestic animals.Formule :C19H17N5O7S3Degré de pureté :98.26%Couleur et forme :SolidMasse moléculaire :523.56NADPH tetrasodium salt
CAS :NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety ofFormule :C21H26N7Na4O17P3Degré de pureté :97.15% - >99.99%Couleur et forme :SolidMasse moléculaire :833.35DIM-C-pPhOH
CAS :CDIM8 (DIM-C-pPhOH) opposes NR4A1, halts TGF-β breast cancer migration, induces ROS/ER stress, and mimics Nur77 RNAi in pancreatic cancer.Formule :C23H18N2ODegré de pureté :98.61% - 99.93%Couleur et forme :SolidMasse moléculaire :338.4Ref: TM-T4400
2mg42,00€5mg62,00€10mg79,00€25mg144,00€50mg215,00€100mg356,00€200mg469,00€1mL*10mM (DMSO)56,00€Rilmenidine hemifumarate
CAS :Rilmenidine hemifumarate (S-3341 hemifumarate) is an I1 imidazoline receptor and α2-adrenergic receptor agonist that induces autophagy.Formule :C10H16N2OC4H4O4Degré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :238.28XL019
CAS :XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.Formule :C25H28N6O2Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :444.53Ref: TM-T3072
2mg43,00€5mg63,00€10mg92,00€25mg150,00€50mg215,00€100mg321,00€200mg477,00€1mL*10mM (DMSO)78,00€tubuloside B
CAS :Tubuloside B from Cistanche salsa stems guards SH-SY5Y cells against TNFalpha-induced apoptosis.
Formule :C31H38O16Degré de pureté :97.59% - 99.72%Couleur et forme :SolidMasse moléculaire :666.62Benzarone
CAS :Benzarone (Benzarona) is a potent inhibitor of human uric acid transporter 1 (URAT1, IC50 = 2.8 μM in oocyte). Benzarone lowers the level of uric acid serum.Formule :C17H14O3Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :266.29PF-4989216
CAS :PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110α, p110β, p110γ, p110δ, and VPS34, respectively.Formule :C18H13FN6OSDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :380.4Ref: TM-T6938
2mg39,00€5mg65,00€10mg101,00€25mg187,00€50mg329,00€100mg398,00€200mg565,00€1mL*10mM (DMSO)67,00€PCNA-I1
CAS :PCNA-I1 is an inhibitor targeting PCNA chromatin association in prostate cancer.
Formule :C17H14N2O2SDegré de pureté :97.64%Couleur et forme :SolidMasse moléculaire :310.37Fluazinam
CAS :Fluazinam: a pyridinamine fungicide, broad-spectrum, strongly inhibits S. sclerotiorum mycelial growth.Formule :C13H4Cl2F6N4O4Degré de pureté :98% - 99.98%Couleur et forme :Light Yellow CrystalsMasse moléculaire :465.09TPCK
CAS :TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesisFormule :C17H18ClNO3SDegré de pureté :97.33%Couleur et forme :PowderMasse moléculaire :351.85TASIN-1 Hydrochloride
CAS :TASIN-1 Hydrochloride (TASIN-1 HCl) is a selective inhibitor of truncated APC that acts by selectively killing colorectal cancer cells that express truncatedFormule :C18H29ClN2O3SDegré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :388.95Ref: TM-T24855
1mg73,00€5mg136,00€10mg187,00€25mg318,00€50mg452,00€100mg627,00€200mg845,00€1mL*10mM (DMSO)142,00€Pexidartinib
CAS :Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potentialFormule :C20H15ClF3N5Degré de pureté :98.34% - 99.45%Couleur et forme :SolidMasse moléculaire :417.81Ref: TM-T2115
5mg46,00€10mg58,00€25mg90,00€50mg114,00€100mg145,00€200mg192,00€500mg333,00€1mL*10mM (DMSO)49,00€Lonicerin
CAS :Lonicerin: antioxidant, anti-arthritic, antifungal; potential for combined fungal arthritis treatment from C. albicans.Formule :C27H30O15Degré de pureté :99.77% - 99.96%Couleur et forme :SolidMasse moléculaire :594.52Glafenine Hydrochloride
CAS :Glafenine Hydrochloride is an anti-inflammatory agent.Formule :C19H17ClN2O4·HClDegré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :409.26Nutlin-3b
CAS :Nutlin-3b, a less potent (+)-enantiomer of Nutlin-3, inhibits p53/MDM2 at IC50: 13.6 μM, 150x weaker than Nutlin-3a.Formule :C30H30Cl2N4O4Degré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :581.49CCPA
CAS :CCPA (2-chloro-N(6)cyclopentyladenosine) is a potent and selective agonist of adenosine A1 receptorFormule :C15H20ClN5O4Degré de pureté :99.1%Couleur et forme :Off-White To Light Yellow SolidMasse moléculaire :369.8Rasagiline Mesylate
CAS :Rasagiline Mesylate (AGN1135) is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.Formule :C13H17NO3SDegré de pureté :99.33%Couleur et forme :White PowderMasse moléculaire :267.34MIRA-1
CAS :MIRA-1 (WRN Helicase Inhibitor) is a restorer of wild-type p53 conformation/cellular function and selectively inhibits Werner syndrome WRN helicase activityFormule :C8H9NO4Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :183.16Lanperisone
CAS :Lanperisone is a muscle relaxant.Formule :C15H18F3NOCouleur et forme :SolidMasse moléculaire :285.3AT7519 Hydrochloride
CAS :AT7519 Hydrochloride (AT7519 HCl) is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9.Formule :C16H18Cl3N5O2Degré de pureté :99.66% - 99.9%Couleur et forme :SolidMasse moléculaire :418.71Ivachtin
CAS :Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remaining
Formule :C20H21N3O7SDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :447.46TASIN-1
CAS :TASIN-1 is a small molecule inhibitor of mutant adenomatous polyposis coli (APC).Formule :C18H28N2O3SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :352.49Ref: TM-T22632
1mg37,00€5mg79,00€10mg124,00€25mg255,00€50mg409,00€100mg605,00€500mg1.288,00€1mL*10mM (DMSO)87,00€Deferitrin
CAS :Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.Formule :C11H11NO4SDegré de pureté :98.71%Couleur et forme :SolidMasse moléculaire :253.27Ref: TM-T19692
1mg99,00€5mg222,00€10mg344,00€25mg550,00€50mg773,00€100mg1.063,00€1mL*10mM (DMSO)205,00€EF24
CAS :EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.Formule :C19H15F2NODegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :311.33Ref: TM-T27242
1g1.510,00€1mg40,00€5mg85,00€10mg133,00€25mg235,00€50mg354,00€100mg533,00€500mg1.130,00€1mL*10mM (DMSO)93,00€Dexrazoxane
CAS :Dexrazoxane (ICRF-187) is a mitosis-blocking anticancer drug, iron chelator, and anthracycline cardioprotectant.Formule :C11H16N4O4Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :268.27Terameprocol
CAS :Terameprocol (EM-1421), a synthetic NDGA derivative, shows potent anti-HIV, antiangiogenic, and anticancer properties.Formule :C22H30O4Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :358.47YUM70
CAS :YUM70 inhibits GRP78 (IC50: 1.5μM), inducing ER stress and apoptosis in pancreatic cancer.Formule :C21H19ClN2O4Degré de pureté :97.25%Couleur et forme :SolidMasse moléculaire :398.84Ref: TM-T8901
1mg46,00€5mg92,00€10mg128,00€25mg250,00€50mg369,00€100mg525,00€200mg710,00€1mL*10mM (DMSO)90,00€SC144
CAS :SC144 is an orally active small-molecule gp130 inhibitor.Formule :C16H11FN6ODegré de pureté :99.20%Couleur et forme :SolidMasse moléculaire :322.3BTdCPU
CAS :BTdCPU is a potent activator of heme-regulated eIF2α kinase (HRI) . BTdCPU promotes eIF2α phosphorylation and induced apoptosis in resistant cell.Formule :C13H8Cl2N4OSDegré de pureté :98.94% - 99.59%Couleur et forme :SolidMasse moléculaire :339.2Ref: TM-T7150
1mg138,00€5mg286,00€10mg442,00€25mg713,00€50mg1.018,00€100mg1.369,00€500mg2.673,00€1mL*10mM (DMSO)236,00€TM5441
CAS :TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.Formule :C21H17ClN2O6Degré de pureté :97.62% - 99.09%Couleur et forme :SolidMasse moléculaire :428.823-Nitropropanoic acid
CAS :3-Nitropropanoic acid (Bovinocidin) is an irreversible inhibitor of succinate dehydrogenase.Formule :C3H5NO4Degré de pureté :98.35% - 99.94%Couleur et forme :Crystals From Chloroform Physical Description Golden Crystals (From Chloroform) (Ntp 1992)Masse moléculaire :119.08EGFR-IN-12
CAS :EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.Formule :C21H18F3N5ODegré de pureté :98.3% - 99.76%Couleur et forme :SolidMasse moléculaire :413.4Ref: TM-T5168
1mg82,00€5mg159,00€10mg259,00€25mg520,00€50mg740,00€100mg1.008,00€500mg2.015,00€1mL*10mM (DMSO)168,00€Clobenpropit dihydrobromide
CAS :Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07)Formule :C14H19Br2ClN4SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :470.73-O-Methylgallic acid
CAS :3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins andFormule :C8H8O5Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :184.15SPP-86
CAS :SPP-86 is an effective and selective cell-permeable inhibitor of RET tyrosine kinase with an IC50 of 8 nM.Formule :C16H15N5Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :277.32Ref: TM-T16923
1mg46,00€5mg90,00€10mg144,00€25mg281,00€50mg447,00€100mg650,00€500mg1.369,00€1mL*10mM (DMSO)90,00€GSK963
CAS :GSK963 (Racemate), a structurally distinct, potent and selective inhibitor of RIP1 kinase(IC50=29 nM).Formule :C14H18N2ODegré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :230.31Ref: TM-T5054
1mg34,00€2mg48,00€5mg74,00€10mg113,00€25mg222,00€50mg358,00€100mg523,00€1mL*10mM (DMSO)82,00€Epothilone B
CAS :Epothilone B (EPO 906) is a compound isolated from the myxobacterium Sorangium cellulosum.Formule :C27H41NO6SDegré de pureté :99.79% - 99.84%Couleur et forme :White PowderMasse moléculaire :507.68Ref: TM-T6075
1mg34,00€2mg48,00€5mg63,00€10mg94,00€25mg203,00€50mg369,00€100mg537,00€1mL*10mM (DMSO)70,00€GSK2982772
CAS :GSK2982772 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1)with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively.Formule :C20H19N5O3Degré de pureté :99.27% - 99.31%Couleur et forme :SolidMasse moléculaire :377.4
