Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(127 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(90 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6170 produits trouvés pour "Apoptose"
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MPTP hydrochloride
CAS :MPTP hydrochloride is a precursor of MPP+, a dopamine neurotoxin with blood-brain barrier permeability.Formule :C12H16ClNDegré de pureté :96.35% - >99.99%Couleur et forme :SolidMasse moléculaire :209.72Ref: TM-T4081
5mg34,00€10mg52,00€25mg80,00€50mg131,00€100mg177,00€200mg281,00€500mg447,00€1mL*10mM (DMSO)50,00€K858 (Racemic)
CAS :K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.Formule :C13H15N3O2SDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :277.34ELR510444
CAS :ELR510444 (LR510444) is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM.Formule :C19H16N2O2S2Degré de pureté :97.67% - 98.69%Couleur et forme :SolidMasse moléculaire :368.47YH239-EE
CAS :YH239-EE, the ethyl ester of YH239, is a potent p53-MDM2 antagonist and an apoptosis inducer.Formule :C25H27Cl2N3O4Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :504.41CHR-6494 TFA
CAS :CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.Formule :C18H17F3N6O2Degré de pureté :99.50%Couleur et forme :SolidMasse moléculaire :406.36Ref: TM-T9521
1mg60,00€5mg122,00€10mg190,00€25mg318,00€50mg452,00€100mg627,00€200mg845,00€1mL*10mM (DMSO)142,00€Tolcapone
CAS :Tolcapone (Ro 40-7592) is a catechol-O-methyltransferase inhibitor used in the therapy of Parkinson disease as adjunctive therapy in combination with levodopaFormule :C14H11NO5Degré de pureté :98.93% - 99.68%Couleur et forme :SolidMasse moléculaire :273.24Ref: TM-T6708
5mg35,00€10mg50,00€25mg82,00€50mg92,00€100mg124,00€200mg170,00€500mg284,00€1mL*10mM (DMSO)52,00€TAK-243
CAS :TAK-243 (MLN7243) is a selective inhibitor of the ubiquitin-activating enzyme UAE (IC50=1 nM).Formule :C19H20F3N5O5S2Degré de pureté :98.09% - 98.93%Couleur et forme :SolidMasse moléculaire :519.52Ref: TM-T16974
1mg46,00€2mg60,00€5mg90,00€10mg142,00€25mg254,00€50mg434,00€100mg623,00€1mL*10mM (DMSO)102,00€Obatoclax Mesylate
CAS :Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, andFormule :C20H19N3O·CH4O3SDegré de pureté :99.58% - 99.88%Couleur et forme :SolidMasse moléculaire :413.49Ibandronate sodium monohydrate
CAS :Ibandronate sodium monohydrate (BM-210955) is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.Formule :C9H24NNaO8P2Degré de pureté :99.62%Couleur et forme :White Crystalline PowderMasse moléculaire :359.23GSK2256098
CAS :GSK2256098 (GTPL7939) is a small molecule FAK kinase inhibitor.Formule :C20H23ClN6O2Degré de pureté :99.46% - 99.74%Couleur et forme :SolidMasse moléculaire :414.89Ref: TM-T2281
1mg44,00€2mg57,00€5mg84,00€10mg130,00€25mg249,00€50mg424,00€100mg625,00€500mg1.314,00€1mL*10mM (DMSO)84,00€PP1
CAS :PP1 (AGL 1872), a specific and effective Src inhibitor, is with IC50 for Lck/Fyn is 5 nM/ 6 nM, respectively.Formule :C16H19N5Degré de pureté :99% - 99.88%Couleur et forme :Off-White To Grey SolidMasse moléculaire :281.36Ref: TM-T6196
1mg38,00€2mg50,00€5mg84,00€10mg112,00€25mg190,00€50mg268,00€100mg421,00€500mg945,00€1mL*10mM (DMSO)89,00€Penicillic acid
CAS :Penicillic acid, a mycotoxin from Aspergillus/Penicillium, blocks Fas ligand apoptosis and is cytotoxic to rat lung macrophages.Formule :C8H10O4Degré de pureté :98%Couleur et forme :Needles From Petroleum Ether Slight Yellow PowderMasse moléculaire :170.16Amifostine sodium
CAS :Amifostine sodium is a phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.Formule :C5H15N2NaO3PSCouleur et forme :SolidMasse moléculaire :237.21MK-4101
CAS :MK-4101 inhibits Hedgehog pathway, causing apoptosis and reduced proliferation in cancer cells.Formule :C24H24F5N5ODegré de pureté :98.2% - 99.13%Couleur et forme :SolidMasse moléculaire :493.47UTL-5g
CAS :UTL-5g is a chemoprotective TNF-α inhibitor reducing cisplatin side effects and toxicity in liver, kidneys, and blood.
Formule :C11H8Cl2N2O2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :271.1Glutathione sodium
CAS :Glutathione sodium, a water-soluble form of PAO, blocks blood vessel formation and cancer growth.Formule :C10H16N3NaO6SCouleur et forme :SolidMasse moléculaire :329.3Vatalanib dihydrochloride
CAS :Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR.Formule :C20H15ClN4·2HClDegré de pureté :99.16%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :419.732-Chloroadenosine
CAS :2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectivelyFormule :C10H12ClN5O4Degré de pureté :99.23%Couleur et forme :White PowderMasse moléculaire :301.69L-BUTHIONINE-(S,R)-SULFOXIMINE
CAS :L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase that induces oxidative stress by depleting GSH.Formule :C8H18N2O3SDegré de pureté :97.07% - ≥98%Couleur et forme :White Fine PowderMasse moléculaire :222.31XL019
CAS :XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.Formule :C25H28N6O2Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :444.53Ref: TM-T3072
2mg43,00€5mg63,00€10mg92,00€25mg150,00€50mg215,00€100mg321,00€200mg477,00€1mL*10mM (DMSO)78,00€Vandetanib
CAS :Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.Formule :C22H24BrFN4O2Degré de pureté :99.7% - >99.99%Couleur et forme :White SolidMasse moléculaire :475.35Ref: TM-T1656
10mg50,00€25mg65,00€50mg92,00€100mg166,00€200mg224,00€500mg359,00€1mL*10mM (DMSO)52,00€DB1976 dihydrochloride
CAS :DB1976 dihydrochloride (DB1976 2HCl), a transcription factor PU.1 inhibitor, has potential anti-inflammatory activity for the study of metabolic dysfunction.Formule :C20H18Cl2N8SeDegré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :520.28EPZ004777 hydrochloride
CAS :EPZ004777 hydrochloride (EPZ004777 HCl) is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.Formule :C28H42ClN7O4Couleur et forme :SolidMasse moléculaire :576.13Suberoyl bis-hydroxamic acid
CAS :SBHA is an HDAC inhibitor, an enzyme key to transcription, cell cycle, and development.Formule :C8H16N2O4Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :204.22PF-4989216
CAS :PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110α, p110β, p110γ, p110δ, and VPS34, respectively.Formule :C18H13FN6OSDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :380.4Ref: TM-T6938
2mg39,00€5mg65,00€10mg101,00€25mg187,00€50mg329,00€100mg398,00€200mg565,00€1mL*10mM (DMSO)67,00€WT-161
CAS :WT161 is a potent and selective inhibitor of HDAC6 (IC50:0.40 nM).Formule :C27H30N4O3Degré de pureté :95.98% - 98.34%Couleur et forme :SolidMasse moléculaire :458.55Tubastatin A
CAS :Tubastatin A: Selective HDAC6 inhibitor, IC50 of 15 nM, 1000x less effective on other isozymes except HDAC8.Formule :C20H21N3O2Degré de pureté :97.22% - 99.51%Couleur et forme :SolidMasse moléculaire :335.4Ref: TM-T1966
10mg46,00€25mg60,00€50mg74,00€100mg105,00€200mg160,00€500mg259,00€1mL*10mM (DMSO)44,00€Pifithrin-μ
CAS :Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.Formule :C8H7NO2SDegré de pureté :99.33% - 99.79%Couleur et forme :SolidMasse moléculaire :181.21Pexidartinib
CAS :Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potentialFormule :C20H15ClF3N5Degré de pureté :98.34% - 99.45%Couleur et forme :SolidMasse moléculaire :417.81Ref: TM-T2115
5mg46,00€10mg58,00€25mg90,00€50mg114,00€100mg145,00€200mg192,00€500mg333,00€1mL*10mM (DMSO)49,00€SR-318
CAS :SR-318 inhibits TNF-α (IC50=283 nM), selectively targets p38 MAPK: IC50 of 5nM (p38α), 32nM (p38β), 6.11μM (p38α/β).Formule :C27H33N5O2Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :459.58Ref: TM-T12997
2mg35,00€5mg55,00€10mg92,00€25mg166,00€50mg259,00€100mg371,00€200mg533,00€1mL*10mM (DMSO)55,00€Rasagiline Mesylate
CAS :Rasagiline Mesylate (AGN1135) is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.Formule :C13H17NO3SDegré de pureté :99.33%Couleur et forme :White PowderMasse moléculaire :267.34Lanperisone
CAS :Lanperisone is a muscle relaxant.Formule :C15H18F3NOCouleur et forme :SolidMasse moléculaire :285.3Mitoxantrone
CAS :Mitoxantrone: anthracenedione antibiotic, disrupts DNA/RNA replication, binds to topoisomerase II, less cardiotoxic than doxorubicin.Formule :C22H28N4O6Degré de pureté :96.29% - 98.74%Couleur et forme :Blue PowderMasse moléculaire :444.48AT7519 Hydrochloride
CAS :AT7519 Hydrochloride (AT7519 HCl) is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9.Formule :C16H18Cl3N5O2Degré de pureté :99.66% - 99.9%Couleur et forme :SolidMasse moléculaire :418.71Obacunone
CAS :Obacunone: cytotoxic to prostate cells, anti-S. Typhimurium, may inhibit breast cancer and aromatase, trigger apoptosis.Formule :C26H30O7Degré de pureté :98% - ≥95%Couleur et forme :White PowderMasse moléculaire :454.51Ref: TM-T3390
2mg35,00€5mg48,00€10mg70,00€25mg104,00€50mg153,00€100mg216,00€200mg320,00€1mL*10mM (DMSO)52,00€Oxibendazole
CAS :Oxibendazole: a benzimidazole antiparasitic for horses and pets against various worms.Formule :C12H15N3O3Degré de pureté :99.3% - 99.88%Couleur et forme :Crystalline SolidMasse moléculaire :249.27Loganin
CAS :Loganin inhibits Cox-1, suppresses TNF-α, and has antioxidant and anti-melanogenic properties.Formule :C17H26O10Degré de pureté :99.01% - 99.9%Couleur et forme :White PowderMasse moléculaire :390.38SHR0302
CAS :SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3,Formule :C18H22N8O2SDegré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :414.48Ref: TM-T9195
1mg80,00€5mg183,00€10mg298,00€25mg512,00€50mg817,00€100mg1.311,00€1mL*10mM (DMSO)167,00€L-Threonic acid magnesium salt
CAS :L-Threonic acid magnesium salt (L-TAMS) increases synapse density and memory ability in both aged rats and late stage Alzheimer’s disease (AD) model mice.Formule :C8H14MgO10Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :294.5SPP-86
CAS :SPP-86 is an effective and selective cell-permeable inhibitor of RET tyrosine kinase with an IC50 of 8 nM.Formule :C16H15N5Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :277.32Ref: TM-T16923
1mg46,00€5mg90,00€10mg144,00€25mg281,00€50mg447,00€100mg650,00€500mg1.369,00€1mL*10mM (DMSO)90,00€GSK963
CAS :GSK963 (Racemate), a structurally distinct, potent and selective inhibitor of RIP1 kinase(IC50=29 nM).Formule :C14H18N2ODegré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :230.31Ref: TM-T5054
1mg34,00€2mg48,00€5mg74,00€10mg113,00€25mg222,00€50mg358,00€100mg523,00€1mL*10mM (DMSO)82,00€RET V804M-IN-1
CAS :RET V804M-IN-1 (RETV804M kinase inhibitor) is a wt-RET -selective RETV804M kinase inhibitors(IC50 = 20 nM).Formule :C19H16N6ODegré de pureté :97.94% - 99.62%Couleur et forme :SolidMasse moléculaire :344.37Ref: TM-T8467
1mg35,00€2mg50,00€5mg74,00€10mg90,00€25mg157,00€50mg236,00€100mg334,00€200mg495,00€1mL*10mM (DMSO)82,00€Ethyl 3,4-dihydroxybenzoate
CAS :Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.Formule :C9H10O4Degré de pureté :99.88%Couleur et forme :White Crystal Or PowderMasse moléculaire :182.17Levistolide A
CAS :1. Levistolide A (Diligustilide) inhibits liver fibrosis and angiogenesis.Formule :C24H28O4Degré de pureté :98.93% - 99.22%Couleur et forme :SolidMasse moléculaire :380.48Ref: TM-T6S1292
1mg34,00€5mg65,00€10mg94,00€25mg137,00€50mg193,00€100mg286,00€200mg423,00€1mL*10mM (DMSO)73,00€Ac-DEVD-AMC
CAS :Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .Formule :C30H37N5O13Degré de pureté :98.20%Couleur et forme :White PowderMasse moléculaire :675.64Cabozantinib S-malate
CAS :Cabozantinib S-malate (XL184) is the salt form of cabozantinib, an orally bioavailable, small molecule RTK inhibitor with potential antineoplastic activity.Formule :C32H30FN3O10Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :635.59Thalidomide-NH-PEG1-NH2 hydrochloride
CAS :Thalidomide-NH-PEG1-NH2 hydrochloride (4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl) is a synthetic E3 ligase ligand-Formule :C17H21ClN4O5Degré de pureté :97.13%Couleur et forme :SolidMasse moléculaire :396.83SZL P1-41
CAS :SZL P1-41 inhibits Skp2, blocks complex formation, and halts ubiquitination, promoting cell senescence, reducing glycolysis, and exhibiting antitumor effects.Formule :C24H24N2O3SDegré de pureté :99.60% - 99.87%Couleur et forme :SolidMasse moléculaire :420.52Garcinol
CAS :Garcinol: inhibits HATs/PCAF (IC50=7/5 μM), anti-inflammatory, anti-cancer, anti-cholinesterase (AChE IC50=0.66 μM, BChE IC50=7.39 μM).Formule :C38H50O6Degré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :602.8Panobinostat
CAS :Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity.
Formule :C21H23N3O2Degré de pureté :97.2% - 99.81%Couleur et forme :Yellow SolidMasse moléculaire :349.43
