Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(126 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(91 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6170 produits trouvés pour "Apoptose"
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Prucalopride Succinate
CAS :Prucalopride Succinate is a 5-HT4 receptor agonist with Ki 2.5 nM (5-HT4a) and 8 nM (5-HT4b).Formule :C18H26ClN3O3·C4H6O4Degré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :485.96Dihydrocapsaicin
CAS :Dihydrocapsaicin, similar to capsaicin, is an irritant found in Capsicum, used in "pure" capsaicin products at about 10%, activates VR1, and is an antioxidant.Formule :C18H29NO3Degré de pureté :99.8% - ≥95%Couleur et forme :White CrystalMasse moléculaire :307.43Abacavir sulfate
CAS :Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activityFormule :C14H18N6OH2O4SDegré de pureté :99.79% - 99.85%Couleur et forme :White To Off-White SolidMasse moléculaire :335.38Fipronil
CAS :Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family.Formule :C12H4Cl2F6N4OSDegré de pureté :97.21%Couleur et forme :Solid PowderMasse moléculaire :437.15Isobavachalcone
CAS :Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury inFormule :C20H20O4Degré de pureté :98% - 99.76%Couleur et forme :SolidMasse moléculaire :324.37Thalidomide-O-C4-NH2 hydrochloride
CAS :Thalidomide-linker 9: a cereblon ligand, E3 ligase conjugate for PROTAC tech.Formule :C17H20ClN3O5Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :381.81KX2-361
CAS :KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastomaFormule :C24H24FN3O2Degré de pureté :99.64% - 99.68%Couleur et forme :SolidMasse moléculaire :405.46Ref: TM-T9411
1mg77,00€5mg161,00€10mg224,00€25mg366,00€50mg515,00€100mg692,00€200mg888,00€1mL*10mM (DMSO)172,00€GSK-J4
CAS :GSK-J4 (GSK J4 HCl) is a cell permeable prodrug of GSK-J1, a dual inhibitor of the H3K27me3/me2 demethylases JMJD3/KDM6B and UTX/KDM6A. Cost effective and quality assured.Formule :C24H27N5O2Degré de pureté :98.24% - 99.98%Couleur et forme :SolidMasse moléculaire :417.5Ref: TM-T3100
2mg52,00€5mg86,00€10mg122,00€25mg215,00€50mg345,00€100mg523,00€200mg663,00€1mL*10mM (DMSO)134,00€MS7972
CAS :MS7972 is CREBBP inhibitor that blocks human p53 and CREB binding protein association. MS7972 can almost completely block this BRD interaction at 50 μMFormule :C14H13NO2Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :227.26Ref: TM-T8774
1mg54,00€5mg105,00€10mg173,00€25mg295,00€50mg425,00€100mg583,00€200mg785,00€1mL*10mM (DMSO)116,00€Bardoxolone
CAS :Bardoxolone (CDDO) inhibits iNOS, COX-2 in cells; IC50=0.4nM. Reduces ROS/RNS, DNA damage, & cancer growth; triggers apoptosis & boosts antioxidant genes.Formule :C31H41NO4Degré de pureté :97.9% - 98.97%Couleur et forme :SolidMasse moléculaire :491.66Nelarabine
CAS :Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.Formule :C11H15N5O5Degré de pureté :98.10% - 99.6%Couleur et forme :White SolidMasse moléculaire :297.27Ref: TM-T6603
1mg40,00€2mg54,00€5mg84,00€10mg133,00€25mg234,00€50mg414,00€100mg520,00€500mg1.099,00€1mL*10mM (DMSO)84,00€Coniferaldehyde
CAS :Coniferaldehyde (Ferulaldehyde) is a member of the class of cinnamaldehydes. Coniferaldehyde has a role as an antifungal agent and a plant metabolite.Formule :C10H10O3Degré de pureté :97.71% - 99.96%Couleur et forme :SolidMasse moléculaire :178.18Medicarpin
CAS :Medicarpin, an ER agonist, stimulates osteoblasts, enhances peak bone mass, has no uterine effects, and is orally bioavailable.Formule :C16H14O4Degré de pureté :99.32% - 99.86%Couleur et forme :SolidMasse moléculaire :270.28Ref: TM-TN1918
1mg109,00€5mg260,00€10mg385,00€25mg628,00€50mg872,00€100mg1.153,00€200mg1.584,00€1mL*10mM (DMSO)235,00€QNZ
CAS :QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.Formule :C22H20N4ODegré de pureté :99.17% - 99.18%Couleur et forme :White SolidMasse moléculaire :356.42Ref: TM-T6204
1mg40,00€2mg54,00€5mg88,00€10mg133,00€25mg178,00€50mg313,00€100mg465,00€200mg673,00€1mL*10mM (DMSO)87,00€Cystamine dihydrochloride
CAS :Cystamine dihydrochloride is a radiation-protective agent. It also protects against carbon tetrachloride liver damage.Formule :C4H14Cl2N2S2Degré de pureté :98.91% - 99.81%Couleur et forme :White PowderMasse moléculaire :225.19JKE-1674
CAS :JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.Formule :C20H20Cl2N4O4Degré de pureté :98.02% - 98.4%Couleur et forme :SolidMasse moléculaire :451.3Ref: TM-T37314
1mg49,00€5mg105,00€10mg170,00€25mg281,00€50mg439,00€100mg708,00€200mg964,00€1mL*10mM (DMSO)117,00€3-Nitropropanoic acid
CAS :3-Nitropropanoic acid (Bovinocidin) is an irreversible inhibitor of succinate dehydrogenase.Formule :C3H5NO4Degré de pureté :98.35% - 99.94%Couleur et forme :Crystals From Chloroform Physical Description Golden Crystals (From Chloroform) (Ntp 1992)Masse moléculaire :119.08AX-024 hydrochloride
CAS :AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of IL-6, TNFα, IFN-γ, IL-10 and IL-17A.Formule :C21H23ClFNO2Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :375.87Ref: TM-T4403
2mg34,00€5mg50,00€10mg75,00€25mg145,00€50mg260,00€100mg485,00€200mg690,00€1mL*10mM (DMSO)55,00€IMT1
CAS :IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.Formule :C21H21NO4Degré de pureté :98.07% - 98.14%Couleur et forme :SolidMasse moléculaire :351.4Ref: TM-T8841
1mg77,00€5mg166,00€10mg285,00€25mg533,00€50mg763,00€100mg1.054,00€1mL*10mM (DMSO)178,00€LY294002
CAS :LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).Formule :C19H17NO3Degré de pureté :98% - 99.96%Couleur et forme :Pale Yellow SolidMasse moléculaire :307.34Triptonide
CAS :Triptonide treats autoimmune diseases, has antileukemic/tumor effects, is anti-inflammatory, and boosts IL-37.Formule :C20H22O6Degré de pureté :99.11% - 99.64%Couleur et forme :White Crystalline PowderMasse moléculaire :358.39Ref: TM-T5S1058
1mg52,00€2mg74,00€5mg108,00€10mg158,00€25mg268,00€50mg409,00€100mg595,00€200mg833,00€1mL*10mM (DMSO)133,00€Palmatine chloride
CAS :Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.Formule :C21H22ClNO4Degré de pureté :97.9% - 99.47%Couleur et forme :SolidMasse moléculaire :387.86PFI-90
CAS :PFI-90, a selective histone demethylase (KDM3B) inhibitor, targets PAX3-FOXO1 action and demonstrates potential antitumor activity.Formule :C11H10N4ODegré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :214.22BML-210
CAS :BML-210 (CAY10433) is a new-type HDAC inhibitor.Formule :C20H25N3O2Degré de pureté :96.37% - 98.12%Couleur et forme :SolidMasse moléculaire :339.43Vandetanib
CAS :Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.Formule :C22H24BrFN4O2Degré de pureté :99.7% - >99.99%Couleur et forme :White SolidMasse moléculaire :475.35Ref: TM-T1656
10mg50,00€25mg65,00€50mg92,00€100mg166,00€200mg224,00€500mg359,00€1mL*10mM (DMSO)52,00€Trifloxystrobin
CAS :Trifloxystrobin is a fungicide against R. solani in sugar beets with EC50s: 23.0 μg/L for Daphnia neonates, 1.7 μg/L for embryos.Formule :C20H19F3N2O4Degré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :408.37Taurochenodeoxycholic acid sodium
CAS :Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).Formule :C26H44NNaO6SDegré de pureté :98.23% - 99.56%Couleur et forme :White To Off-White PowderMasse moléculaire :521.68Cidofovir sodium
CAS :Cidofovir sodium, an injectable antiviral for AIDS-related CMV retinitis, is a DNA polymerase inhibitor.Formule :C8H12N3Na2O6PCouleur et forme :SolidMasse moléculaire :323.1523Thalidomide-O-amido-PEG2-C2-NH2 TFA
CAS :Thalidomide-based E3 ligase ligand-linker for PROTAC with PEG2 bridge; cereblon-targeted.Formule :C23H27F3N4O10Degré de pureté :95.74% - 99%Couleur et forme :SolidMasse moléculaire :576.48Piperazine Erastin
CAS :Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.Formule :C35H41ClN6O4Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :645.19Ref: TM-T16540
1mg92,00€5mg165,00€10mg268,00€25mg537,00€50mg879,00€100mg1.161,00€200mg1.594,00€500mg2.367,00€1mL*10mM (DMSO)227,00€Diclofenac Potassium
CAS :Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.Formule :C14H10Cl2KNO2Degré de pureté :99.51%Couleur et forme :White To Yellowish Crystalline PowderMasse moléculaire :334.24CCF642
CAS :CCF642 (AC1LYELL) is a novel PDI-inhibiting compound with antimyeloma activity.Formule :C15H10N2O4S3Degré de pureté :97.12% - 98.82%Couleur et forme :SolidMasse moléculaire :378.45Ref: TM-T6800
1mg34,00€2mg46,00€5mg63,00€10mg93,00€25mg170,00€50mg281,00€100mg432,00€200mg618,00€1mL*10mM (DMSO)66,00€N-Formyl-Met-Leu-Phe
CAS :N-Formyl-Met-Leu-Phe (N-Formyl-MLF) (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).Formule :C21H31N3O5SDegré de pureté :98.69% - 98.69%Couleur et forme :SolidMasse moléculaire :437.55(ZE)-SU9516
CAS :(ZE)-SU9516 is a selectively potent ATP-competitive inhibitor of CDKs.Formule :C13H11N3O2Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :241.25Ref: TM-T8819
1mg90,00€5mg131,00€10mg170,00€25mg248,00€50mg321,00€100mg419,00€500mg938,00€1mL*10mM (DMSO)117,00€Mocetinostat
CAS :Mocetinostat (MG0103) is an orally available HDAC inhibitor with most potency for HDAC1 (IC50: 0.15 μM), 2- to 10- fold selectivity against HDAC2/3/11.Formule :C23H20N6ODegré de pureté :99% - 99.21%Couleur et forme :SolidMasse moléculaire :396.44ERK1/2 inhibitor 2
CAS :ERK1/2 inhibitor 2 (ASTX029) is a selective and orally bioavailable ERK 1/2 inhibitor, with potential antineoplastic activity.Formule :C29H31ClFN5O5Degré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :584.04Mitoxantrone
CAS :Mitoxantrone: anthracenedione antibiotic, disrupts DNA/RNA replication, binds to topoisomerase II, less cardiotoxic than doxorubicin.Formule :C22H28N4O6Degré de pureté :96.29% - 98.74%Couleur et forme :Blue PowderMasse moléculaire :444.48GSK4112
CAS :GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.Formule :C18H21ClN2O4SDegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :396.89Cichoric Acid
CAS :Cichoric Acid (Dicaffeoyltartaric acid) is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues.Formule :C22H18O12Degré de pureté :97.87% - 98.77%Couleur et forme :SolidMasse moléculaire :474.37Isolongifolene
CAS :Isolongifolene ((-)-Isolongifolene), a tricyclic sesquiterpene isolated from Murraya koenigii, exhibits antioxidant, anti-inflammatory, anticancer, andFormule :C15H24Degré de pureté :90.13% - 99.46%Couleur et forme :Colorless Or Light Yellow LiquidMasse moléculaire :204.35Benidipine hydrochloride
CAS :Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.Formule :C28H32ClN3O6Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :542.03Triglycidyl isocyanurate
CAS :Triglycidyl isocyanurate (Teroxirone) is a cancer-research chemical with DNA-altering properties, also used in metal finishing.Formule :C12H15N3O6Degré de pureté :99.01%Couleur et forme :White Solid ParticulatesMasse moléculaire :297.26HJC0152 hydrochloride
CAS :HJC0152 hydrochloride (HJC0152) is a signal transducer and activator of transcription 3 (STAT3) inhibitor.Formule :C15H14Cl3N3O4Degré de pureté :99.01% - 99.06%Couleur et forme :SolidMasse moléculaire :406.64Abacavir monosulfate
CAS :Abacavir monosulfate: oral HIV inhibitor, anticancer; crosses blood-brain barrier, suppresses telomerase.Formule :C14H20N6O5SCouleur et forme :SolidMasse moléculaire :384.41CM-272
CAS :CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.Formule :C28H38N4O3Degré de pureté :97.83%Couleur et forme :SolidMasse moléculaire :478.63PK11000
CAS :PK11000 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53.Formule :C6H5ClN2O4SDegré de pureté :99.70%Couleur et forme :SolidMasse moléculaire :236.63Taurodeoxycholic acid sodium hydrate
CAS :Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.Formule :C26H46NNaO7SDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :539.70Caudatin
CAS :Caudatin is one of the species of C-21 steroidal glycosides mainly isolated from the root of Cynanchum bungei Decne and exhibits potent anticancer activities.Formule :C28H42O7Degré de pureté :98.83% - 99.84%Couleur et forme :SolidMasse moléculaire :490.63Ref: TM-T3150
1mg52,00€5mg100,00€10mg166,00€25mg279,00€50mg398,00€100mg532,00€200mg705,00€1mL*10mM (DMSO)119,00€Tubastatin A
CAS :Tubastatin A: Selective HDAC6 inhibitor, IC50 of 15 nM, 1000x less effective on other isozymes except HDAC8.Formule :C20H21N3O2Degré de pureté :97.22% - 99.51%Couleur et forme :SolidMasse moléculaire :335.4Ref: TM-T1966
10mg46,00€25mg60,00€50mg74,00€100mg105,00€200mg160,00€500mg259,00€1mL*10mM (DMSO)44,00€Clodronate disodium tetrahydrate
CAS :Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.Formule :CH10Cl2Na2O10P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :360.92
