Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(126 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(91 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6170 produits trouvés pour "Apoptose"
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CCF642
CAS :CCF642 (AC1LYELL) is a novel PDI-inhibiting compound with antimyeloma activity.Formule :C15H10N2O4S3Degré de pureté :97.12% - 98.82%Couleur et forme :SolidMasse moléculaire :378.45Ref: TM-T6800
1mg34,00€2mg46,00€5mg63,00€10mg93,00€25mg170,00€50mg281,00€100mg432,00€200mg618,00€1mL*10mM (DMSO)66,00€Darapladib
CAS :Darapladib (SB-480848) is a lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with an IC50 value of 0.25 nM.Cost-effective and quality-assured.Formule :C36H38F4N4O2SDegré de pureté :99.82% - >99.99%Couleur et forme :SolidMasse moléculaire :666.77Ref: TM-T6109
1mg42,00€2mg52,00€5mg87,00€10mg125,00€25mg180,00€50mg309,00€100mg499,00€200mgÀ demander1mL*10mM (DMSO)116,00€C-DIM12
CAS :C-DIM12 boosts Nurr1 gene expression, heightens Nurr1 protein in neurons, and improves survival against 6-OHDA.Formule :C23H17ClN2Degré de pureté :97.72% - ≥95%Couleur et forme :SolidMasse moléculaire :356.85L-685458
CAS :L-685458 (L-685,458) is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.Formule :C39H52N4O6Degré de pureté :99.62% - 99.80%Couleur et forme :SolidMasse moléculaire :672.85Ref: TM-T6870
1mg113,00€5mg334,00€10mg520,00€25mg840,00€50mg1.144,00€100mg1.521,00€1mL*10mM (DMSO)497,00€BTR-1
CAS :5-Benzylidene-3-ethyl rhodanine(BTR-1 (5-Benzylidene-3-ethyl rhodanine)) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.Formule :C12H11NOS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :249.35Ref: TM-T5822
2mg34,00€5mg50,00€10mg84,00€25mg137,00€50mg200,00€100mg304,00€200mg442,00€1mL*10mM (DMSO)56,00€Momelotinib
CAS :Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.Formule :C23H22N6O2Degré de pureté :97.07% - 99.56%Couleur et forme :SolidMasse moléculaire :414.46Ref: TM-T1849
1mg35,00€2mg50,00€5mg77,00€10mg89,00€25mg158,00€50mg245,00€100mg385,00€200mg592,00€1mL*10mM (DMSO)84,00€SC99
CAS :SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.Formule :C15H8Cl2FN3ODegré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :336.15Ref: TM-T8719
1mg43,00€5mg87,00€10mg133,00€25mg227,00€50mg344,00€100mg429,00€200mg597,00€1mL*10mM (DMSO)94,00€GSK4112
CAS :GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.Formule :C18H21ClN2O4SDegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :396.89Oleic acid
CAS :Oleic acid, a common unsaturated fat, is used in oleates, lotions, and as a pharma solvent.Formule :C18H34O2Degré de pureté :97.14% - 99.91%Couleur et forme :Colorless Or Nearly Colorless Liq (Above 5-7 Deg C) Oleic Acid Is A Colorless To Pale Yellow Liquid With A Mild Odor Floats On Water (Uscg 1999)Masse moléculaire :282.46Necroptosis-IN-1
CAS :Necroptosis-IN-1 is a potent necroptosis inhibitor of RIPK1. It is an analog of Necrostatin-1.Formule :C12H10ClN3O2Degré de pureté :99.73% - 99.8%Couleur et forme :SolidMasse moléculaire :263.68Ref: TM-T9305
1mg60,00€5mg111,00€10mg177,00€25mg301,00€50mg425,00€100mg605,00€200mg797,00€1mL*10mM (DMSO)141,00€Triglycidyl isocyanurate
CAS :Triglycidyl isocyanurate (Teroxirone) is a cancer-research chemical with DNA-altering properties, also used in metal finishing.Formule :C12H15N3O6Degré de pureté :99.01%Couleur et forme :White Solid ParticulatesMasse moléculaire :297.26Anagrelide
CAS :Anagrelide (Xagrid) is a Platelet-reducing Agent.Formule :C10H7Cl2N3ODegré de pureté :99.53% - >99.99%Couleur et forme :SolidMasse moléculaire :256.09BC-1258
CAS :BC-1258 is a unique small molecule F-box/LRR-repeat protein 2 (FBXL2) activator.Formule :C22H22N4S2Degré de pureté :97.48% - 99.64%Couleur et forme :SolidMasse moléculaire :406.57Sodium Oxamate
CAS :Sodium Oxamate (Oxamic acid sodium salt) is an LDH inhibitor that specifically inhibits LDHA.Formule :C2H2NNaO3Degré de pureté :99.23% - ≥98%Couleur et forme :White Crystalline PowderMasse moléculaire :111.03LY2857785
CAS :LY2857785 is a type I competitive and reversible ATP kinase inhibitor against CDK7/CDK8/CDK9 (IC50s: 246 nM/16 nM/11 nM).Formule :C26H36N6ODegré de pureté :99.68%Couleur et forme :Solid PowderMasse moléculaire :448.6Ref: TM-TQ0060
1mg50,00€2mg71,00€5mg105,00€10mg170,00€25mg334,00€50mg537,00€100mg863,00€1mL*10mM (DMSO)117,00€AVN-944
CAS :AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.
Formule :C25H27N5O5Degré de pureté :99.07% - ≥95%Couleur et forme :SolidMasse moléculaire :477.51Levobupivacaine hydrochloride
CAS :Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.Formule :C18H28N2O·HClDegré de pureté :99.74%Couleur et forme :White Crystalline PowderMasse moléculaire :324.89Mdivi-1
CAS :Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM).Formule :C15H10Cl2N2O2SDegré de pureté :96.57% - 99.23%Couleur et forme :SolidMasse moléculaire :353.22Ref: TM-T1907
5mg44,00€10mg52,00€25mg95,00€50mg144,00€100mg215,00€200mg319,00€500mg530,00€1mL*10mM (DMSO)48,00€Niraparib
CAS :Niraparib (MK-4827) inhibits PARP1/PARP2 (IC50: 3.8/2.1 nM), effective on BRCA mutant cancers, 330x less effective on PARP3, V-PARP, Tank1.Formule :C19H20N4ODegré de pureté :98% - 99.91%Couleur et forme :SolidMasse moléculaire :320.39Ref: TM-T3231
5mg57,00€10mg84,00€25mg105,00€50mg137,00€100mg205,00€200mg304,00€500mg515,00€1mL*10mM (DMSO)63,00€GSK621
CAS :GSK621 is a specific and potent AMPK activator.Formule :C26H20ClN3O5Degré de pureté :97.02% - 97.05%Couleur et forme :SolidMasse moléculaire :489.91R406
CAS :R406 (R-406 besylate) is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.Formule :C22H23FN6O5·C6H6O3SDegré de pureté :97.67% - 98.82%Couleur et forme :SolidMasse moléculaire :628.63Ref: TM-T6174
1mg46,00€2mg57,00€5mg89,00€10mg142,00€25mg299,00€50mg445,00€100mg647,00€1mL*10mM (DMSO)120,00€VLX600
CAS :VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent.Formule :C17H15N7Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :317.35Mito-LND
CAS :Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.Formule :C43H45BrCl2N3OPDegré de pureté :97.25% - 98.34%Couleur et forme :SolidMasse moléculaire :801.62Taurodeoxycholic acid sodium hydrate
CAS :Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.Formule :C26H46NNaO7SDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :539.70Alemtuzumab
CAS :Alemtuzumab is a humanized monoclonal antibody against CD52 an antigen found on the surface of normal and malignant lymphocytes.
Degré de pureté :97.2% (SDS-PAGE); 96.7% (SEC-HPLC) - 98.00%Couleur et forme :LiquidMasse moléculaire :146.04 kDaChlorfenapyr
CAS :Chlorfenapyr (AC 303630) is a pyrrole insecticide and converts active substances (insecticidal activity) in insects by a multifunctional oxidaseFormule :C15H11BrClF3N2ODegré de pureté :99.33% - 99.49%Couleur et forme :Off-White To Light Brown Powder With An Halide OdorMasse moléculaire :407.61Amifostine trihydrate
CAS :Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.Formule :C5H15N2O3PS·3H2ODegré de pureté :99.71% - 99.80%Couleur et forme :SolidMasse moléculaire :268.27Oxaprozin potassium
CAS :Oxaprozin potassium is an oral COX inhibitor (IC50: 2.2 μM for COX-1, 36 μM for COX-2), induces apoptosis, and blocks NF-κB activation.Formule :C18H14KNO3Couleur et forme :SolidMasse moléculaire :331.412MG-132
CAS :MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor, cell-permeable and reversible,an autophagy activator, induces apoptosis. High-Quality, Low-Cost!Formule :C26H41N3O5Degré de pureté :95% - 99.99%Couleur et forme :White To Off-White PowderMasse moléculaire :475.62Ref: TM-T2154
10mg46,00€25mg84,00€50mg137,00€100mg205,00€200mg356,00€500mg447,00€1mL*10mM (DMSO)44,00€Rosiglitazone
CAS :Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.Formule :C18H19N3O3SDegré de pureté :98.61% - 99.87%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :357.43Autophagy-IN-A9
CAS :Autophagy-IN-A9 is a bioactive chemical.Formule :C15H11ClFN3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :287.72Ref: TM-T9181
2mg34,00€5mg50,00€10mg63,00€25mg110,00€50mg203,00€100mg281,00€200mg420,00€1mL*10mM (DMSO)55,00€Alisertib Sodium
CAS :Alisertib Sodium (MLN 8237 Sodium)is a selective Aurora A inhibitor that causes G2/M phase arrest and chromosomal misalignment, leading to tumour cell apoptosis.Formule :C27H19ClFN4NaO4Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :540.91(E/Z)-NiCur
CAS :Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI) is an inhibitor of p53 with an IC50 value of 0.35 μMFormule :C22H16N2ODegré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :324.38Ref: TM-T9129
1mg49,00€5mg102,00€10mg149,00€25mg245,00€50mg354,00€100mg495,00€200mg673,00€1mL*10mM (DMSO)105,00€Glyphosate
CAS :Glyphosate (Atila) is an herbicide. It also is a possible carcinogen to humans.Formule :C3H8NO5PDegré de pureté :99.12% - 99.91%Couleur et forme :White Crystals (Darkens) Ph (1% Solution In Water) 2 5 (Ntp 1992)Masse moléculaire :169.073-Dehydrotrametenolic acid
CAS :3-Dehydrotrametenolic acid is a potential anticancer agent against H-ras transformed tumor and a promising candidate for a new type of insulin-sensitizing drug.Formule :C30H46O3Degré de pureté :98.5% - 99.25%Couleur et forme :SolidMasse moléculaire :454.68Ref: TM-T5S0620
1mg46,00€5mg92,00€10mg147,00€25mg241,00€50mg349,00€100mg479,00€200mg657,00€1mL*10mM (DMSO)108,00€Tripterin
CAS :Tripterin (Celastrol) is an proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with antioxidant and anti-inflammatory effects.Formule :C29H38O4Degré de pureté :98.56% - 99.8%Couleur et forme :Red Crystalline PowderMasse moléculaire :450.61Dp44mT
CAS :Dp44mT, a effective iron chelator, has selective antitumor activity.Formule :C14H15N5SDegré de pureté :99% - 99.02%Couleur et forme :SolidMasse moléculaire :285.37Icaritin
CAS :Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity.Formule :C21H20O6Degré de pureté :97.69% - 99.76%Couleur et forme :SolidMasse moléculaire :368.38PAC-1
CAS :PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer and Thoracic Cancers.Formule :C23H28N4O2Degré de pureté :96.78% - 99.76%Couleur et forme :SolidMasse moléculaire :392.49Carnosic acid
CAS :Carnosic acid is a lipid absorption inhibitor, endowed with antioxidative, antimicrobial, photoprotective potential, and antiproliferative properties.Formule :C20H28O4Degré de pureté :98.31% - 99.5%Couleur et forme :Yellow PowderMasse moléculaire :332.43BAM7
CAS :BAM 7 is a direct and specific activator of proapoptotic Bax (EC50: 3.3 μM).Formule :C21H19N5O2SDegré de pureté :98.51% - 98.68%Couleur et forme :SolidMasse moléculaire :405.47Ref: TM-T2453
2mg34,00€5mg49,00€10mg64,00€25mg122,00€50mg197,00€100mg295,00€200mg442,00€1mL*10mM (DMSO)50,00€EPZ004777
CAS :EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.Formule :C28H41N7O4Degré de pureté :98.99% - 99.32%Couleur et forme :SolidMasse moléculaire :539.67OTS964
CAS :OTS964 is an oral TOPK inhibitor (IC50: 28nM), also targets CDK11, especially CDK11B (Kd: 40nM).Formule :C23H24N2O2SCouleur et forme :SolidMasse moléculaire :392.51Divalproex Sodium
CAS :Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted byFormule :C8H16O2·C8H15O2·NaDegré de pureté :99.87%Couleur et forme :A White Powder With A Characteristic OdorMasse moléculaire :310.41Ref: TM-T6474
10mg37,00€25mg52,00€50mg74,00€100mg110,00€200mg178,00€500mg318,00€1mL*10mM (DMSO)52,00€PCI-34051
CAS :PCI-34051 is an effective and selective HDAC8 inhibitor (IC50: 10 nM).Formule :C17H16N2O3Degré de pureté :97.219% - 98.29%Couleur et forme :SolidMasse moléculaire :296.32Ref: TM-T6325
5mg57,00€10mg90,00€25mg175,00€50mg334,00€100mg537,00€500mg1.134,00€1mL*10mM (DMSO)63,00€(Rac)-Benpyrine
CAS :(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.Formule :C16H16N6ODegré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :308.34Ref: TM-T8692
1mg46,00€2mg62,00€5mg92,00€10mg152,00€25mg295,00€50mg442,00€100mg620,00€200mg875,00€1mL*10mM (DMSO)105,00€Etonogestrel
CAS :Etonogestrel (Implanon) is a steroidal progestin used as hormonal contraceptives.Formule :C22H28O2Degré de pureté :99.59% - 99.59%Couleur et forme :SolidMasse moléculaire :324.46Ref: TM-T2567
2mg34,00€5mg50,00€10mg70,00€25mg109,00€50mg167,00€100mg310,00€200mg484,00€1mL*10mM (DMSO)50,00€S63845
CAS :S63845 is a selective myeloid leukemia 1（MCL1) inhibitor that binds to human MCL1 with a Kd of 0.19 nM.Cost-effective and quality-assured.Formule :C39H37ClF4N6O6SDegré de pureté :97.7% - ≥98%Couleur et forme :SolidMasse moléculaire :829.26Rapanone
CAS :Rapanone (2,5-Dihydroxy-3-tridecyl-[1,4]benzoquinone) is a natural benzoquinone that is a potent and selective inhibitor of human synovial PLA2.Formule :C19H30O4Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :322.44PRT062607 hydrochloride
CAS :PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk. PRT062607 displays at least 80-fold selectivity for Syk over other kinases.Formule :C19H23N9O·HClDegré de pureté :97.7% - 99.81%Couleur et forme :SolidMasse moléculaire :429.91Ref: TM-T2696
1mg57,00€2mg81,00€5mg120,00€10mg177,00€25mg309,00€50mg475,00€200mg898,00€1mL*10mM (DMSO)132,00€
