Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(134 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(93 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6222 produits trouvés pour "Apoptose"
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Z-YVAD-FMK
CAS :AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.Formule :C31H39FN4O9Degré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :630.66Ixazomib
CAS :Ixazomib (MLN2238) is a boron-based peptide proteasome inhibitor targeting β5 site (IC50: 3.4 nM), also affecting β1 and β2 sites.Formule :C14H19BCl2N2O4Degré de pureté :98% - 99.77%Couleur et forme :SolidMasse moléculaire :361.03SPP-86
CAS :SPP-86 is an effective and selective cell-permeable inhibitor of RET tyrosine kinase with an IC50 of 8 nM.Formule :C16H15N5Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :277.32Ref: TM-T16923
1mg46,00€5mg90,00€1mL*10mM (DMSO)90,00€10mg144,00€25mg281,00€50mg447,00€100mg650,00€500mg1.369,00€RET V804M-IN-1
CAS :RET V804M-IN-1 (RETV804M kinase inhibitor) is a wt-RET -selective RETV804M kinase inhibitors(IC50 = 20 nM).Formule :C19H16N6ODegré de pureté :97.94% - 99.62%Couleur et forme :SolidMasse moléculaire :344.37Ref: TM-T8467
1mg35,00€2mg50,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg90,00€25mg157,00€50mg236,00€100mg334,00€200mg495,00€Ethyl 3,4-dihydroxybenzoate
CAS :Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.Formule :C9H10O4Degré de pureté :99.88%Couleur et forme :White Crystal Or PowderMasse moléculaire :182.17LY-364947
CAS :LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGFβR-I.Formule :C17H12N4Degré de pureté :99.65% - 99.96%Couleur et forme :SolidMasse moléculaire :272.3Ref: TM-T2048
5mg62,00€1mL*10mM (DMSO)69,00€10mg78,00€25mg136,00€50mg241,00€100mg354,00€200mg530,00€500mg830,00€Ac-DEVD-AMC
CAS :Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .Formule :C30H37N5O13Degré de pureté :98.20%Couleur et forme :White PowderMasse moléculaire :675.64Liproxstatin-1
CAS :Liproxstatin-1 is a potent and selective inhibitor of iron death (IC50=22 nM).Formule :C19H21ClN4Degré de pureté :97.11% - 99.44%Couleur et forme :SolidMasse moléculaire :340.85Ref: TM-T2376
1mg39,00€5mg85,00€1mL*10mM (DMSO)85,00€10mg130,00€25mg244,00€50mg390,00€100mg495,00€200mg712,00€Garcinol
CAS :Garcinol: inhibits HATs/PCAF (IC50=7/5 μM), anti-inflammatory, anti-cancer, anti-cholinesterase (AChE IC50=0.66 μM, BChE IC50=7.39 μM).Formule :C38H50O6Degré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :602.8AS1842856
CAS :AS1842856 is a Foxo1 inhibitor that blocks the transcriptional activity of Foxo1. AS1842856 has autophagy inhibitory activity. Cost-effective and quality-assured.Formule :C18H22FN3O3Degré de pureté :99.36% - >99.99%Couleur et forme :SolidMasse moléculaire :347.38Necrostatin 2 racemate
CAS :Necrostatin 2 racemate (Necrostatin-2 racemate) is an potent and specific inhibitor of RIPK1.Formule :C13H12ClN3O2Degré de pureté :98% - 99.5%Couleur et forme :SolidMasse moléculaire :277.71Ref: TM-T7504
1mg62,00€5mg102,00€1mL*10mM (DMSO)133,00€10mg160,00€25mg289,00€50mg500,00€100mg705,00€500mg1.431,00€Pralsetinib
CAS :Pralsetinib (Blu667) (BLU-667) is a highly potent, selective RET inhibitor (IC50s: 0.4, 0.3, 0.4, 0.4, and 0.4 nM for WT RET, RET mutants V804L, V804M, M918TFormule :C27H32FN9O2Degré de pureté :97.88% - 99.8%Couleur et forme :SolidMasse moléculaire :533.6Selpercatinib
CAS :"Selpercatinib (LOXO-292) is a RET tyrosine kinase inhibitor with IC50s of 14.0, 24.1, 530.7 nM for different RET mutations."Formule :C29H31N7O3Degré de pureté :99.89% - >99.99%Couleur et forme :SolidMasse moléculaire :525.6Ref: TM-T8222
2mg34,00€5mg49,00€1mL*10mM (DMSO)56,00€10mg84,00€25mg166,00€50mg259,00€100mg477,00€200mg692,00€500mg1.035,00€BMS-1166
CAS :BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.Formule :C36H33ClN2O7Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :641.11Ref: TM-T5697
1mg71,00€5mg146,00€1mL*10mM (DMSO)197,00€10mg213,00€25mg406,00€50mg602,00€100mg893,00€200mg1.198,00€RIPA-56
CAS :RIPA-56 is an inhibitor of RIP1Formule :C13H19NO2Degré de pureté :99.53% - 99.93%Couleur et forme :SolidMasse moléculaire :221.3Ref: TM-T7795
5mg35,00€10mg50,00€1mL*10mM (DMSO)52,00€25mg89,00€50mg129,00€100mg202,00€200mg299,00€500mg504,00€Pembrolizumab
CAS :Pembrolizumab (MK-3475) is a humanized monoclonal antibody.Cost-effective and quality-assured.Degré de pureté :95% - 99.70%Couleur et forme :LiquidMasse moléculaire :149 kDaRPI-1
CAS :RPI-1 is a competitive, potent ATP-dependent Ret kinase inhibitor.Formule :C17H15NO4Degré de pureté :98.91% - ≥95%Couleur et forme :SolidMasse moléculaire :297.31Eclitasertib
CAS :Eclitasertib is a potent inhibitor of receptor-interacting protein kinase 1 (RIPK1, IC50 of <1 µΜ).Formule :C19H18N6O3Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :378.38Ref: TM-T9702
1mg101,00€2mg142,00€5mg215,00€1mL*10mM (DMSO)236,00€10mg340,00€25mg618,00€50mg858,00€100mg1.224,00€ZM-447439
CAS :ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.Formule :C29H31N5O4Degré de pureté :99.11% - 99.59%Couleur et forme :Pale Yellow SolidMasse moléculaire :513.59Rottlerin
CAS :Rottlerin (NSC-56346), a Mallotus Philippinensis extract, inhibits PKC (3-100 μM IC50); triggers apoptosis by activating caspase 3.Formule :C30H28O8Degré de pureté :97.41% - 99.44%Couleur et forme :Orange To Brown PowderMasse moléculaire :516.54HS-1371
CAS :HS-1371 is a novel kinase inhibitor of receptor-interacting protein kinase 3 (RIP3) with an IC50 of 20.8 nM.Formule :C24H24N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :384.47Metformin
CAS :Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability.Formule :C4H11N5Degré de pureté :99.77% - >99.99%Couleur et forme :SolidMasse moléculaire :129.16Ref: TM-T8526
10mg44,00€1mL*10mM (DMSO)44,00€25mg66,00€50mg93,00€100mg102,00€500mg250,00€2500mg414,00€Neotame
CAS :Neotame (HSDB 7965), a white dipeptide methyl ester, is a potent non-nutritive sweetener used in many foods.Formule :C20H30N2O5Degré de pureté :99.44%Couleur et forme :White Or Off White Crystalline PowderMasse moléculaire :378.46BBT594
CAS :BBT594 (NVP-BBT594)(NVP-BBT594) is a potent inhibitor of receptor tyrosine kinase RET,Treatment of cancer.Formule :C28H30F3N7O3Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :569.58Belnacasan
CAS :Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.Formule :C24H33ClN4O6Degré de pureté :96.53% - 99.5%Couleur et forme :SolidMasse moléculaire :508.99Ref: TM-T6090
2mg34,00€5mg52,00€1mL*10mM (DMSO)52,00€10mg81,00€25mg161,00€50mg222,00€100mg396,00€200mg585,00€Denosumab
CAS :Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligandFormule :C6404H9912N1724O2004S50Degré de pureté :95.9% (SDS-PAGE); 98.4% (SEC-HPLC) - 99.90%Couleur et forme :LiquidMasse moléculaire :144.71 kDaGSK-923295
CAS :GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).Formule :C32H38ClN5O4Degré de pureté :96.22% - 98.02%Couleur et forme :SolidMasse moléculaire :592.13Ref: TM-T2039
1mg49,00€5mg97,00€1mL*10mM (DMSO)136,00€10mg168,00€25mg283,00€50mg432,00€100mg605,00€200mg852,00€Mimosine
CAS :L-Mimosine (Leucenol) is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca and acts as an iron chelator.Formule :C8H10N2O4Degré de pureté :99.2% - 99.84%Couleur et forme :Crystals From Water SolidMasse moléculaire :198.18U-73122
CAS :U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.Formule :C29H40N2O3Degré de pureté :97.50%Couleur et forme :Solid Off-WhiteMasse moléculaire :464.64PHA-767491 hydrochloride
CAS :PHA-767491 (CAY-10572) is a potent Cdc7/CDK9 inhibitor (IC50: 10/34 nM), selective against GSK3-β, CDK1/2, CDK5, MK2, CHK2, PLK1.Formule :C12H12ClN3ODegré de pureté :99.56% - 99.92%Couleur et forme :SolidMasse moléculaire :249.69KY-05009
CAS :KY-05009 blocks TGF-β1 EMT in lung cancer cells, inhibits TNIK, Wnt genes, induces apoptosis, and is an ATP-competitive TNIK inhibitor (Ki = 100 nM).Formule :C18H16N4O2SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :352.41Ref: TM-T11793
5mg48,00€1mL*10mM (DMSO)49,00€10mg67,00€25mg111,00€50mg161,00€100mg231,00€200mg335,00€Capmatinib 2HCl
CAS :Capmatinib 2HCl (INC-280 2HCl), a c-MET inhibitor, is potent (IC50 = 0.13 nM), highly specific, and induces apoptosis in tumor cells.Formule :C23H19Cl2FN6ODegré de pureté :98.80%Couleur et forme :SolidMasse moléculaire :485.34Ref: TM-T4260
2mg34,00€5mg49,00€1mL*10mM (DMSO)58,00€10mg64,00€25mg84,00€50mg92,00€100mg126,00€500mg303,00€Urolithin A
CAS :Urolithin A is a metabolite of ellagic acid, which inhibits DNA synthesis and induces apoptosis and autophagy. Cost-effective and quality-assured.Formule :C13H8O4Degré de pureté :99.14% - 99.67%Couleur et forme :SolidMasse moléculaire :228.2Ref: TM-T7174
5mg47,00€1mL*10mM (DMSO)52,00€10mg69,00€25mg123,00€50mg177,00€100mg304,00€200mg447,00€500mg713,00€TJ191
CAS :TJ191 is a selective anti-cancer agent, targeting low TβRIII-expressing malignant T-cell leukemia/lymphoma cells.Formule :C13H21NO2SDegré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :255.38α-Thujone
CAS :α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.Formule :C10H16ODegré de pureté :97.02% - 98.41%Couleur et forme :Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Masse moléculaire :152.23ASP3026
CAS :ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced Malignancies,and Positive for Anaplastic Lymphoma Kinase.Formule :C29H40N8O3SDegré de pureté :98.78% - 99.81%Couleur et forme :SolidMasse moléculaire :580.74CCT 137690
CAS :CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).Formule :C26H31BrN8ODegré de pureté :98.51% - 99.89%Couleur et forme :SolidMasse moléculaire :551.48BTZO-1
CAS :BTZO-1 is an antioxidant response element (ARE) activator with cardioprotective activity.Formule :C13H8N2OSDegré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :240.28Ref: TM-T7845
2mg34,00€5mg50,00€1mL*10mM (DMSO)56,00€10mg85,00€25mg154,00€50mg222,00€100mg331,00€200mg470,00€COTI-2
CAS :COTI-2, an orally available thiosemicarbazone, is an activator of mutant forms of the p53 protein with potential antineoplastic activity.Formule :C19H22N6SDegré de pureté :99% - 99.55%Couleur et forme :SolidMasse moléculaire :366.48Salidroside
CAS :Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola rosea and is a prolyl endopeptidase inhibitor.Cost-effective and quality-assured.Formule :C14H20O7Degré de pureté :97.81%Couleur et forme :Red-Brown Fine PowderMasse moléculaire :300.30Ref: TM-T2717
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg81,00€25mg130,00€50mg178,00€100mg268,00€200mg408,00€C-DIM12
CAS :C-DIM12 boosts Nurr1 gene expression, heightens Nurr1 protein in neurons, and improves survival against 6-OHDA.Formule :C23H17ClN2Degré de pureté :97.72% - ≥95%Couleur et forme :SolidMasse moléculaire :356.85L-685458
CAS :L-685458 (L-685,458) is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.Formule :C39H52N4O6Degré de pureté :99.62% - 99.80%Couleur et forme :SolidMasse moléculaire :672.85Ref: TM-T6870
1mg113,00€5mg334,00€1mL*10mM (DMSO)497,00€10mg520,00€25mg840,00€50mg1.144,00€100mg1.521,00€Serdemetan
CAS :Serdemetan (JNJ-26854165) is an orally bioavailable HDM2 antagonist with potential antineoplastic activity.
Formule :C21H20N4Degré de pureté :98% - 99.51%Couleur et forme :SolidMasse moléculaire :328.41BC-1258
CAS :BC-1258 is a unique small molecule F-box/LRR-repeat protein 2 (FBXL2) activator.Formule :C22H22N4S2Degré de pureté :97.48% - 99.64%Couleur et forme :SolidMasse moléculaire :406.57LY2857785
CAS :LY2857785 is a type I competitive and reversible ATP kinase inhibitor against CDK7/CDK8/CDK9 (IC50s: 246 nM/16 nM/11 nM).Formule :C26H36N6ODegré de pureté :99.68%Couleur et forme :Solid PowderMasse moléculaire :448.6Ref: TM-TQ0060
1mg50,00€2mg71,00€5mg105,00€1mL*10mM (DMSO)117,00€10mg170,00€25mg334,00€50mg537,00€100mg863,00€B-AP15
CAS :B-AP15 (NSC-687852) selectively inhibits 26S proteasome enzymes Usp14 and UCHL5, blocking their activity.Formule :C22H17N3O6Degré de pureté :91.43% - 98.77%Couleur et forme :SolidMasse moléculaire :419.39Niraparib
CAS :Niraparib (MK-4827) inhibits PARP1/PARP2 (IC50: 3.8/2.1 nM), effective on BRCA mutant cancers, 330x less effective on PARP3, V-PARP, Tank1.Formule :C19H20N4ODegré de pureté :98% - 99.91%Couleur et forme :SolidMasse moléculaire :320.39Ref: TM-T3231
5mg57,00€1mL*10mM (DMSO)63,00€10mg84,00€25mg105,00€50mg137,00€100mg205,00€200mg304,00€500mg515,00€GW 441756
CAS :GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM.Formule :C17H13N3ODegré de pureté :97.73% - 99.8%Couleur et forme :SolidMasse moléculaire :275.3R406
CAS :R406 (R-406 besylate) is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.Formule :C22H23FN6O5·C6H6O3SDegré de pureté :97.67% - 98.82%Couleur et forme :SolidMasse moléculaire :628.63Ref: TM-T6174
1mg46,00€2mg57,00€5mg89,00€1mL*10mM (DMSO)120,00€10mg142,00€25mg299,00€50mg445,00€100mg647,00€PS 48
CAS :PS 48 has been shown to be a PKB Kinase (PDK1) activator (Kd: 10.3 μM). This compound selectively binds to the PIF-binding pocket of PKB Kinase (PDK1).Formule :C17H15ClO2Degré de pureté :99.96% - ≥95%Couleur et forme :SolidMasse moléculaire :286.75
