Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(134 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(93 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6222 produits trouvés pour "Apoptose"
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GW 5074
CAS :GW 5074 (Raf1 Kinase Inhibitor I)(IC50=9 nM) is an effective and specific c-Raf inhibitor.Formule :C15H8Br2INO2Degré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :520.94Lubiprostone
CAS :Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.Formule :C20H32F2O5Degré de pureté :97.31% - 98.54%Couleur et forme :White Odorless Crystals Or Crystalline PowderMasse moléculaire :390.46Alisertib Sodium
CAS :Alisertib Sodium (MLN 8237 Sodium)is a selective Aurora A inhibitor that causes G2/M phase arrest and chromosomal misalignment, leading to tumour cell apoptosis.Formule :C27H19ClFN4NaO4Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :540.91(Z)-Guggulsterone
CAS :(Z)-Guggulsterone triggers apoptosis in prostate cancer cells and blocks angiogenesis by inhibiting VEGF pathways.Formule :C21H28O2Degré de pureté :98.93% - 99.72%Couleur et forme :SolidMasse moléculaire :312.45Staurosporine
CAS :Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-FgrFormule :C28H26N4O3Degré de pureté :99.24% - 99.82%Couleur et forme :Off-White PowderMasse moléculaire :466.53Ref: TM-T6680
1mg58,00€2mg82,00€5mg92,00€1mL*10mM (DMSO)103,00€10mg138,00€25mg234,00€50mg380,00€100mg565,00€500mg1.215,00€Xevinapant
CAS :Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.Formule :C32H43N5O4Degré de pureté :98% - 99.94%Couleur et forme :SolidMasse moléculaire :561.71Ref: TM-T6763
1mg40,00€2mg54,00€5mg88,00€10mg124,00€1mL*10mM (DMSO)138,00€25mg260,00€50mg416,00€100mg647,00€200mg954,00€SKF-86002
CAS :SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).Formule :C16H12FN3SDegré de pureté :98% - 99.85%Couleur et forme :SolidMasse moléculaire :297.35Alogliptin Benzoate
CAS :Alogliptin Benzoate, a potent DPP-4 inhibitor with >10,000-fold selectivity over DPP-8/9, may also curb TLR-4-induced inflammation.Formule :C25H27N5O4Degré de pureté :99.94% - >99.99%Couleur et forme :White PowderMasse moléculaire :461.51R406 free base
CAS :R406 free base (R406 (free base)) is a potent Syk inhibitor.Formule :C22H23FN6O5Degré de pureté :97.64% - 99.11%Couleur et forme :SolidMasse moléculaire :470.45Ref: TM-T2467
1mg44,00€5mg66,00€1mL*10mM (DMSO)69,00€10mg92,00€25mg177,00€50mg319,00€100mg507,00€500mg1.063,00€Olanzapine HCl
CAS :Olanzapine HCl, an FDA-approved atypical antipsychotic for schizophrenia and bipolar disorder, resembles clozapine and quetiapine.Formule :C17H21ClN4SCouleur et forme :SolidMasse moléculaire :348.89Angelicin
CAS :Angelicin (Isopsoralen), is a furanocoumarin with anti-Y, antiviral, anti-inflammatory activity.Formule :C11H6O3Degré de pureté :99.86% - 99.89%Couleur et forme :White SolidMasse moléculaire :186.164-IBP
CAS :4-IBP is a selective σ1 agonist with a high level of affinity for the σ1 receptor (Ki = 1.7 nM) and a moderate affinity for the σ2 receptor (Ki = 25.2 nM) .Formule :C19H21IN2ODegré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :420.29PS 48
CAS :PS 48 has been shown to be a PKB Kinase (PDK1) activator (Kd: 10.3 μM). This compound selectively binds to the PIF-binding pocket of PKB Kinase (PDK1).Formule :C17H15ClO2Degré de pureté :99.96% - ≥95%Couleur et forme :SolidMasse moléculaire :286.75DC661
CAS :DC661 is a palmitoyl-protein thioesterase 1 (PPT1) inhibitor that acts as an anti-lysosomal agent by inhibiting autophagy, demonstrating anti-cancer activity.Formule :C31H39Cl2N5Degré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :552.58Ref: TM-T5538
1mg80,00€2mg105,00€5mg188,00€1mL*10mM (DMSO)230,00€10mg319,00€25mg545,00€50mg780,00€100mg1.074,00€CDPPB
CAS :CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5).
Formule :C23H16N4ODegré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :364.4McMMAF
CAS :McMMAF is a protective group-conjugated MMAF.Formule :C49H76N6O11Degré de pureté :99.65% - >99.99%Couleur et forme :SolidMasse moléculaire :925.16ML311
CAS :ML311 is a selective inhibitor of the Mcl-1/Bim interaction.Formule :C23H24F3N3ODegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :415.45PI-103
CAS :PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).Formule :C19H16N4O3Degré de pureté :97.79% - 99.3%Couleur et forme :SolidMasse moléculaire :348.36Citronellyl acetate
CAS :Citronellyl acetate is a natural productFormule :C12H22O2Degré de pureté :98%Couleur et forme :LiquidMasse moléculaire :198.30NSC59984
CAS :NSC59984, a p53 pathway activator, induces mutant p53 protein degradation and p73 activation.Formule :C12H15N3O4Degré de pureté :99.33% - 99.59%Couleur et forme :SolidMasse moléculaire :265.27Ref: TM-T6910
5mg66,00€1mL*10mM (DMSO)73,00€10mg102,00€25mg205,00€50mg334,00€100mg537,00€500mg1.134,00€Torkinib
CAS :Torkinib (PP 242) (PP 242) is a selective and ATP-competitive mTOR inhibitor (IC50: 8 nM). It also inhibits mTORC1/2 (IC50s: 30/58 nM).Formule :C16H16N6ODegré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :308.34Ref: TM-T2414
5mg54,00€1mL*10mM (DMSO)59,00€10mg71,00€25mg90,00€50mg129,00€100mg215,00€200mg319,00€500mg530,00€GSK2656157
CAS :GSK2656157 is a highly specific and ATP-competitive PERK inhibitor (IC50: 0.9 nM) in a cell-free assay.Formule :C23H21FN6ODegré de pureté :98.59% - >99.99%Couleur et forme :SolidMasse moléculaire :416.45Ref: TM-T2654
2mg34,00€5mg52,00€1mL*10mM (DMSO)52,00€10mg77,00€25mg135,00€50mg245,00€100mg442,00€200mg598,00€Thalidomide-5-methyl
CAS :Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand. Thalidomide-5-methyl is used in the recruitment of CRBN protein.Formule :C14H12N2O4Degré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :272.26Ref: TM-T40503
1mg65,00€1mL*10mM (DMSO)130,00€5mg144,00€10mg210,00€25mg359,00€50mg504,00€100mg680,00€200mg919,00€Acenocoumarol
CAS :Acenocoumarol is a Vitamin K antagonist and used as an anticoagulant.Formule :C19H15NO6Degré de pureté :99.95%Couleur et forme :Crystals SolidMasse moléculaire :353.33PRIMA-1
CAS :PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.Formule :C9H15NO3Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :185.22Ref: TM-T6954
5mg49,00€1mL*10mM (DMSO)54,00€10mg70,00€25mg133,00€50mg195,00€100mg349,00€200mg518,00€500mg830,00€AZD3759 hydrochloride
CAS :AZD3759 hydrochloride is an oral, CNS-penetrant EGFR inhibitor with IC50s of 0.2/0.3/0.2 nM.Formule :C22H24Cl2FN5O3Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :496.36Ref: TM-T4249
2mg34,00€5mg46,00€1mL*10mM (DMSO)49,00€10mg62,00€25mg94,00€50mg167,00€100mg265,00€200mg385,00€20(R)-Ginsenoside Rh2
CAS :20(R)-Ginsenoside Rh2 (Ginsenoside Rh2) is a minor stereoisomer of ginsenoside Rh2, possesses matrix metalloproteinase inhibitory.Formule :C36H62O8Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :622.87Ref: TM-T3813
1mg46,00€5mg87,00€1mL*10mM (DMSO)119,00€10mg123,00€25mg192,00€50mg264,00€100mg378,00€200mg552,00€Domatinostat
CAS :Domatinostat (4SC202) is a selective class I HDAC inhibitor. Domatinostat also displays inhibitory activity against Lysine specific demethylase 1 (LSD1).Formule :C23H21N5O3SDegré de pureté :99.57% - 99.74%Couleur et forme :SolidMasse moléculaire :447.513,4-Dicaffeoylquinic acid
CAS :3,4-Dicaffeoylquinic acid (Isochlorogenic acid B) has antioxidant activity.Formule :C25H24O12Degré de pureté :96.33% - 98.82%Couleur et forme :SolidMasse moléculaire :516.45Ref: TM-T6S1525
1mg40,00€5mg80,00€10mg101,00€1mL*10mM (DMSO)103,00€25mg167,00€50mg240,00€100mg355,00€500mg845,00€Gemcitabine hydrochloride
CAS :Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.Formule :C9H11F2N3O4·HClDegré de pureté :99.28% - 99.98%Couleur et forme :White Crystalline Granular OdorlessMasse moléculaire :299.66Importazole
CAS :Importazole is an inhibitor of the nuclear transport receptor importin-β.Formule :C20H22N4Degré de pureté :99.6% - >99.99%Couleur et forme :SolidMasse moléculaire :318.42Ref: TM-T3445
5mg49,00€1mL*10mM (DMSO)54,00€10mg69,00€25mg144,00€50mg215,00€100mg356,00€200mg532,00€500mg852,00€Ciprofloxacin hydrochloride monohydrate
CAS :Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) is a fluoroquinolone antibiotic with potent antibacterial activity.
Formule :C17H21ClFN3O4Degré de pureté :99.23% - 99.85%Couleur et forme :White Or Yellowish Crystalline PowderMasse moléculaire :385.82Musk ketone
CAS :Musk ketone may suppress cancer cell growth, induce apoptosis, and boost glutathione S-transferase, potentially aiding cancer protection.Formule :C14H18N2O5Degré de pureté :99.85%Couleur et forme :Yellow Crystals Physical Description Light Yellow Crystalline Solid Insoluble In Water (Ntp 1992)Masse moléculaire :294.30Urolithin C
CAS :Urolithin C is a gut metabolite of ellagic acid. Urolithin C induces apoptosis in PC12 cells through a mitochondria-mediated pathway.Formule :C13H8O5Degré de pureté :98.01% - 99.53%Couleur et forme :SolidMasse moléculaire :244.2Ref: TM-TN7108
5mg50,00€1mL*10mM (DMSO)56,00€10mg84,00€25mg136,00€50mg222,00€100mg334,00€200mg495,00€500mg782,00€XL019
CAS :XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.Formule :C25H28N6O2Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :444.53Ref: TM-T3072
2mg43,00€5mg63,00€1mL*10mM (DMSO)78,00€10mg92,00€25mg150,00€50mg215,00€100mg321,00€200mg477,00€Cabozantinib
CAS :Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).
Formule :C28H24FN3O5Degré de pureté :99.68% - 99.88%Couleur et forme :SolidMasse moléculaire :501.51XI-006
CAS :NSC-207895 (XI-006) suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and regulates MDM2, an E3 ligase.Formule :C11H13N5O4Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :279.25Ref: TM-T6610
1mg52,00€2mg77,00€1mL*10mM (DMSO)108,00€5mg113,00€10mg177,00€25mg409,00€50mg605,00€100mg860,00€500mg1.728,00€Eribulin mesylate
CAS :Eribulin mesylate (E7389), a microtubule inhibitor, treats metastatic breast cancer by halting cell division.Formule :C41H63NO14SDegré de pureté :97.02% - >99.99%Couleur et forme :SolidMasse moléculaire :826Ruxolitinib
CAS :Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.Formule :C17H18N6Degré de pureté :99.4% - >99.99%Couleur et forme :SolidMasse moléculaire :306.36Ref: TM-T1829
5mg55,00€1mL*10mM (DMSO)62,00€10mg71,00€25mg96,00€50mg110,00€100mg146,00€200mg231,00€500mg393,00€L-BUTHIONINE-(S,R)-SULFOXIMINE
CAS :L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase that induces oxidative stress by depleting GSH.Formule :C8H18N2O3SDegré de pureté :97.07% - ≥98%Couleur et forme :White Fine PowderMasse moléculaire :222.31Laquinimod
CAS :Laquinimod (LAQ) is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral
Formule :C19H17ClN2O3Degré de pureté :98.42% - 98.84%Couleur et forme :SolidMasse moléculaire :356.8GSK2801
CAS :GSK2801 is an effective, specific and cell active acetyl-lysine competitive inhibitor of BAZ2A(Kd: 136 nM) and BAZ2B(Kd: 257 nM) bromodomains.Formule :C20H21NO4SDegré de pureté :97.78% - 99.45%Couleur et forme :SolidMasse moléculaire :371.452-Chloroadenosine
CAS :2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectivelyFormule :C10H12ClN5O4Degré de pureté :99.23%Couleur et forme :White PowderMasse moléculaire :301.69Tenovin-3
CAS :Tenovin-3 acts as a p53 activator.Formule :C18H21N3OSDegré de pureté :99.72% - ≥95%Couleur et forme :SolidMasse moléculaire :327.44R-7050
CAS :R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.Formule :C16H8ClF3N4SDegré de pureté :98.64% - 99.8%Couleur et forme :SolidMasse moléculaire :380.77Ref: TM-T4637
1mg34,00€2mg43,00€5mg63,00€1mL*10mM (DMSO)71,00€10mg90,00€25mg195,00€50mg268,00€100mg439,00€200mg623,00€Jaceosidin
CAS :Jaceosidin: anti-oxidant, anti-inflammatory, anti-cancer, immunosuppressive; affects CYP1A2/UGT1A1/UGT1A7 metabolism.Formule :C17H14O7Degré de pureté :98.23% - 99.28%Couleur et forme :SolidMasse moléculaire :330.29WP1066
CAS :WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.Formule :C17H14BrN3ODegré de pureté :98.92% - 99.73%Couleur et forme :SolidMasse moléculaire :356.22NADPH tetrasodium salt
CAS :NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety ofFormule :C21H26N7Na4O17P3Degré de pureté :97.15% - >99.99%Couleur et forme :SolidMasse moléculaire :833.35Millepachine
CAS :Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.Formule :C22H22O4Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :350.41Ref: TM-T38815
1mg52,00€5mg110,00€1mL*10mM (DMSO)127,00€10mg147,00€25mg245,00€50mg358,00€100mg537,00€200mg710,00€JNJ-7706621
CAS :JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.Formule :C15H12F2N6O3SDegré de pureté :99.1% - 99.85%Couleur et forme :SolidMasse moléculaire :394.36Ref: TM-T6126
1mg48,00€1mL*10mM (DMSO)94,00€5mg100,00€10mg155,00€25mg268,00€50mg432,00€100mg595,00€200mg833,00€
