Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(134 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(93 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6222 produits trouvés pour "Apoptose"
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Cyasterone
CAS :Cyasterone (Cyasteron), a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promisingFormule :C29H44O8Degré de pureté :99.32% - 99.70%Couleur et forme :SolidMasse moléculaire :520.65Stattic
CAS :Stattic (STAT3 Inhibitor V) is a STAT3 inhibitor (IC50=5.1 μM) that selectively inhibits STAT3 activation, dimerization, and nuclear translocation.Formule :C8H5NO4SDegré de pureté :98.32% - 99.76%Couleur et forme :SolidMasse moléculaire :211.19Ref: TM-T6308
5mg35,00€10mg51,00€1mL*10mM (DMSO)55,00€25mg85,00€50mg124,00€100mg187,00€200mg279,00€500mg465,00€Pifithrin-α hydrobromide
CAS :Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.Formule :C16H18N2OS·HBrDegré de pureté :97.71% - >99.99%Couleur et forme :SolidMasse moléculaire :367.3Genistein
CAS :Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.Formule :C15H10O5Degré de pureté :98.22% - 99.64%Couleur et forme :Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidMasse moléculaire :270.24(1E,6E)-Bis(demethoxy)curcumin
CAS :(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.Formule :C19H16O4Degré de pureté :97.45% - 98.39%Couleur et forme :SolidMasse moléculaire :308.33Ref: TM-T6S1688
5mg42,00€1mL*10mM (DMSO)49,00€10mg52,00€25mg81,00€50mg105,00€100mg152,00€500mg353,00€AZ 628
CAS :AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc.Formule :C27H25N5O2Degré de pureté :99.50%Couleur et forme :SolidMasse moléculaire :451.52SGI-1027
CAS :SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT).Formule :C27H23N7ODegré de pureté :99.45% - 99.78%Couleur et forme :SolidMasse moléculaire :461.52Ref: TM-T1904
5mg58,00€1mL*10mM (DMSO)74,00€10mg94,00€25mg163,00€50mg296,00€100mg467,00€500mg1.035,00€Chelidonine
CAS :Chelidonine from Chelidonium majus triggers HeLa cell apoptosis, may reverse MDR, boost chemotherapeutics against leukemia, and inhibit cancer cell metastasis.Formule :C20H19NO5Degré de pureté :98% - 99.61%Couleur et forme :SolidMasse moléculaire :353.37Rotenone
CAS :Rotenone, a plant-derived insecticide, inhibits mitochondrial electron transport, found in Leguminosae.Formule :C23H22O6Degré de pureté :89.58% - 99.88%Couleur et forme :Less To Brownish Crystals Or A White To Brownish-White Crystalline Powder Has Neither Odor Nor Taste (Ntp 1992)Masse moléculaire :394.42Epibrassinolide
CAS :Epibrassinolide (BP55) (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator withFormule :C28H48O6Degré de pureté :97.57% - 98.11%Couleur et forme :SolidMasse moléculaire :480.68Goserelin acetate
CAS :Goserelin acetate (Fertilan) is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer.
Formule :C61H88N18O16Degré de pureté :99.77% - >99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :1329.46PIK-75
CAS :PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).
Formule :C16H14BrN5O4SDegré de pureté :98.52% - >99.99%Couleur et forme :SolidMasse moléculaire :452.28Levomenol
CAS :Levomenol, or (-)-α-Bisabolol, is a sesquiterpene in aromatic plant oils with antioxidant, anti-inflammatory, and anti-apoptotic properties.Formule :C15H26ODegré de pureté :96.01%Couleur et forme :Clear To Yellowish LiquidMasse moléculaire :222.37PKR-IN-C16
CAS :PKR-IN-C16: inhibits PKR autophosphorylation and translation blockade; binds ATP site; IC50 of 186-210 nM; protects cells from ER stress damage.Formule :C13H8N4OSDegré de pureté :97.8%Couleur et forme :SolidMasse moléculaire :268.29Ref: TM-T16550
1mg40,00€2mg52,00€5mg84,00€1mL*10mM (DMSO)105,00€10mg130,00€25mg260,00€50mg409,00€100mg605,00€Neferine
CAS :Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.Formule :C38H44N2O6Degré de pureté :98.81% - 99.65%Couleur et forme :SolidMasse moléculaire :624.77Momordin Ic
CAS :Momordin Ic (Momordin 1c) might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunctionFormule :C41H64O13Degré de pureté :98% - 99.69%Couleur et forme :SolidMasse moléculaire :764.94Sal003
CAS :Sal003, an effective cell-permeable analog, inhibitis the eIF2α phosphatase.Formule :C18H15Cl4N3OSDegré de pureté :99.17% - 99.77%Couleur et forme :SolidMasse moléculaire :463.21Ref: TM-T2417
1mg35,00€2mg50,00€5mg70,00€1mL*10mM (DMSO)71,00€10mg98,00€25mg172,00€50mg256,00€100mg380,00€Infigratinib
CAS :Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 andFormule :C26H31Cl2N7O3Degré de pureté :98% - 98.97%Couleur et forme :SolidMasse moléculaire :560.48Ref: TM-T1975
5mg44,00€1mL*10mM (DMSO)48,00€10mg57,00€25mg84,00€50mg90,00€100mg144,00€200mg259,00€500mg437,00€Salvigenin
CAS :Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.Formule :C18H16O6Degré de pureté :99.17% - 99.78%Couleur et forme :SolidMasse moléculaire :328.32Gardenin B
CAS :Gardenin B exhibits superior antiproliferative activity against lung, breast, colon, hepatic and leukaemia cell lines as well as in keratinocytes .Formule :C19H18O7Degré de pureté :98.80% - 99.74%Couleur et forme :SolidMasse moléculaire :358.34Delanzomib
CAS :Delanzomib (CEP-18770) is an oral proteasome inhibitor with an IC50 of 3.8 nM, targeting chymotrypsin-like activity with minimal effect on other activities.Formule :C21H28BN3O5Degré de pureté :95.52% - 99.46%Couleur et forme :SolidMasse moléculaire :413.28Ref: TM-T6027
1mg43,00€1mL*10mM (DMSO)89,00€5mg92,00€10mg133,00€25mg260,00€50mg416,00€100mg625,00€200mg868,00€Telekin
CAS :Telekin, a sesquiterpene lactone from Carpesium divaricatum, strongly inhibits cancer cell growth.Formule :C15H20O3Degré de pureté :99.86% - 99.97%Couleur et forme :SolidMasse moléculaire :248.32AT7519
CAS :AT7519 is a CDK1/2/4/6/9 inhibitor (IC50: 10-210 nM). It is less effective to CDK3 and little active to CDK7.Formule :C16H17Cl2N5O2Degré de pureté :98.88% - 99.65%Couleur et forme :SolidMasse moléculaire :382.24Malabaricone B
CAS :Malabaricone B is a Spice-derived phenolic, it induces mitochondrial damage in lung cancer cells via a p53-independent pathway.Formule :C21H26O4Degré de pureté :99.84% - 99.91%Couleur et forme :SolidMasse moléculaire :342.43(E/Z)-TG003
CAS :(E/Z)-TG003 is a potent and ATP-competitive Cdc2-like kinase (Clk) inhibitor.Formule :C13H15NO2SDegré de pureté :98% - 99.04%Couleur et forme :SolidMasse moléculaire :249.33Ref: TM-T1901
2mg42,00€5mg52,00€1mL*10mM (DMSO)52,00€10mg92,00€25mg164,00€50mg271,00€100mg399,00€200mg567,00€ENMD-2076
CAS :ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Formule :C21H25N7Degré de pureté :97.63% - ≥95%Couleur et forme :SolidMasse moléculaire :375.47m-3M3FBS
CAS :m-3M3FBS is a phospholipase C (PLC) activator.Formule :C16H16F3NO2SDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :343.36Polygalacin D
CAS :Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-inducedFormule :C57H92O27Degré de pureté :98.95% - ≥98%Couleur et forme :SolidMasse moléculaire :1209.4Choline
CAS :Choline is a ubiquitous water soluble nutrient, often associated with the B vitaminsFormule :C5H15NO2Degré de pureté :85% - ≥98%Couleur et forme :LiquidMasse moléculaire :121.18MPTP hydrochloride
CAS :MPTP hydrochloride is a precursor of MPP+, a dopamine neurotoxin with blood-brain barrier permeability.Formule :C12H16ClNDegré de pureté :96.35% - >99.99%Couleur et forme :SolidMasse moléculaire :209.72Ref: TM-T4081
5mg34,00€1mL*10mM (DMSO)50,00€10mg52,00€25mg80,00€50mg131,00€100mg177,00€200mg281,00€500mg447,00€CHR-6494 TFA
CAS :CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.Formule :C18H17F3N6O2Degré de pureté :99.50%Couleur et forme :SolidMasse moléculaire :406.36Ref: TM-T9521
1mg60,00€5mg122,00€1mL*10mM (DMSO)142,00€10mg190,00€25mg318,00€50mg452,00€100mg627,00€200mg845,00€Obatoclax Mesylate
CAS :Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, andFormule :C20H19N3O·CH4O3SDegré de pureté :99.58% - 99.88%Couleur et forme :SolidMasse moléculaire :413.49Ibandronate sodium monohydrate
CAS :Ibandronate sodium monohydrate (BM-210955) is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.Formule :C9H24NNaO8P2Degré de pureté :99.62%Couleur et forme :White Crystalline PowderMasse moléculaire :359.23Neobavaisoflavone
CAS :Neobavaisoflavone: DNA polymerase inhibitor, potential for treating bone loss, anti-inflammatory, reduces ROS, RNS, cytokines in macrophages.Formule :C20H18O4Degré de pureté :99.31% - 99.92%Couleur et forme :SolidMasse moléculaire :322.35Ref: TM-T6S0139
5mg46,00€1mL*10mM (DMSO)49,00€10mg66,00€25mg99,00€50mg144,00€100mg205,00€500mg512,00€RGX-202
CAS :RGX-202 (β-GPA) is an orally active inhibitor of the SLC6A8 transport protein. RGX-202 is a creatine analog that alters skeletal muscle energy expenditure.Formule :C4H9N3O2Degré de pureté :99.67% - 99.8%Couleur et forme :SolidMasse moléculaire :131.13PD173955
CAS :PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR andFormule :C21H16Cl2N4OSDegré de pureté :98.52% - 98.99%Couleur et forme :SolidMasse moléculaire :443.35Ref: TM-T3063
2mg35,00€5mg50,00€10mg92,00€1mL*10mM (DMSO)94,00€25mg166,00€50mg248,00€100mg371,00€200mg530,00€Nobiletin
CAS :Nobiletin: a citrus-derived flavone with anti-inflammatory and anti-cancer properties; water-insoluble, very weak acid.Formule :C21H22O8Degré de pureté :98.65% - 99.76%Couleur et forme :SolidMasse moléculaire :402.39Ref: TM-T2834
5mg54,00€1mL*10mM (DMSO)56,00€10mg84,00€25mg117,00€50mg159,00€100mg251,00€200mg371,00€500mg620,00€OTS514
CAS :OTS514 (OTS514 Hydrochloride) is a potent TOPK inhibitor.Formule :C21H20N2O2SDegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :364.46Ref: TM-T4134L
1mg65,00€5mg144,00€1mL*10mM (DMSO)152,00€10mg222,00€25mg394,00€50mg532,00€100mg743,00€200mg982,00€UTL-5g
CAS :UTL-5g is a chemoprotective TNF-α inhibitor reducing cisplatin side effects and toxicity in liver, kidneys, and blood.
Formule :C11H8Cl2N2O2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :271.1TREM2-IN-1
CAS :TREM2-IN-1 (OPA) is a platinum-based TREM2 inhibitor with anti-cancer and anti-tumor activity, inhibiting the immune-regulatory activity of TREM2 on macrophagesFormule :C46H68N2O20PtDegré de pureté :98.56%Couleur et forme :SolidMasse moléculaire :1164.12Barasertib-HQPA
CAS :Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.
Formule :C26H30FN7O3Degré de pureté :98.43% - 99.29%Couleur et forme :SolidMasse moléculaire :507.56CA-5f
CAS :CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion.Formule :C24H24N2O3Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :388.46Erastin
CAS :Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner, anti-tumor. High-Quality, Low-Cost!Formule :C30H31ClN4O4Degré de pureté :98% - 99.82%Couleur et forme :SolidMasse moléculaire :547.04Ref: TM-T1765
1mg46,00€2x1mg59,00€5x1mg93,00€10x1mg120,00€25x1mg192,00€50x1mg284,00€100x1mg421,00€200x1mg618,00€Avitinib
CAS :Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,Formule :C26H26FN7O2Degré de pureté :99.81% - >99.99%Couleur et forme :SolidMasse moléculaire :487.53Darapladib
CAS :Darapladib (SB-480848) is a lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with an IC50 value of 0.25 nM.Cost-effective and quality-assured.Formule :C36H38F4N4O2SDegré de pureté :99.82% - >99.99%Couleur et forme :SolidMasse moléculaire :666.77Ref: TM-T6109
200mgÀ demander1mg42,00€2mg52,00€5mg87,00€1mL*10mM (DMSO)116,00€10mg125,00€25mg180,00€50mg309,00€100mg499,00€Amifostine trihydrate
CAS :Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.Formule :C5H15N2O3PS·3H2ODegré de pureté :99.71% - 99.80%Couleur et forme :SolidMasse moléculaire :268.27Oxaprozin potassium
CAS :Oxaprozin potassium is an oral COX inhibitor (IC50: 2.2 μM for COX-1, 36 μM for COX-2), induces apoptosis, and blocks NF-κB activation.Formule :C18H14KNO3Couleur et forme :SolidMasse moléculaire :331.4124-Nitroquinoline 1-oxide
CAS :4-Nitroquinoline 1-oxide (4-NQO) is a chemical carcinogen that induces mutations in bacteria, fungi, and animals through the formation of large amounts ofFormule :C9H6N2O3Degré de pureté :97.4% - 99.94%Couleur et forme :Yellow Needles Or Plates From Acetone Physical Description Yellowish-Brown Plates Or Needles Or Yellow Solid (Ntp 1992)Masse moléculaire :190.16Stavudine sodium
CAS :Stavudine sodium, an oral HIV-1/2 inhibitor, also hinders mtDNA replication, NLRP3 inflammasome, and Amyloid-β autophagy, prompting apoptosis.Formule :C10H11N2NaO4Couleur et forme :SolidMasse moléculaire :246.198OTS964
CAS :OTS964 is an oral TOPK inhibitor (IC50: 28nM), also targets CDK11, especially CDK11B (Kd: 40nM).Formule :C23H24N2O2SCouleur et forme :SolidMasse moléculaire :392.51
