Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(134 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(93 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6222 produits trouvés pour "Apoptose"
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Isoalantolactone
CAS :Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.Formule :C15H20O2Degré de pureté :99.75% - 99.94%Couleur et forme :SolidMasse moléculaire :232.32Zoledronic acid monohydrate
CAS :Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.Formule :C5H12N2O8P2Degré de pureté :99.91%Couleur et forme :White To Off-White PowderMasse moléculaire :290.1Toddaculin
CAS :Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of theFormule :C16H18O4Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :274.31Lubiprostone
CAS :Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.Formule :C20H32F2O5Degré de pureté :97.31% - 98.54%Couleur et forme :White Odorless Crystals Or Crystalline PowderMasse moléculaire :390.46Telekin
CAS :Telekin, a sesquiterpene lactone from Carpesium divaricatum, strongly inhibits cancer cell growth.Formule :C15H20O3Degré de pureté :99.86% - 99.97%Couleur et forme :SolidMasse moléculaire :248.32Eprenetapopt
CAS :Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.Formule :C10H17NO3Degré de pureté :98.75% - 99.57%Couleur et forme :SolidMasse moléculaire :199.25Ref: TM-T4414
5mg70,00€1mL*10mM (DMSO)77,00€10mg100,00€25mg195,00€50mg349,00€100mg618,00€500mg1.251,00€AT7519
CAS :AT7519 is a CDK1/2/4/6/9 inhibitor (IC50: 10-210 nM). It is less effective to CDK3 and little active to CDK7.Formule :C16H17Cl2N5O2Degré de pureté :98.88% - 99.65%Couleur et forme :SolidMasse moléculaire :382.24RH01687
CAS :RH01687 is a potent β-cell protector , exhibits β-cell-protective activities against endoplasmic reticulum (ER) stress.Formule :C12H9ClN6O2SDegré de pureté :97.93%Couleur et forme :SolidMasse moléculaire :336.76Clodronic acid disodium salt
CAS :Clodronic acid disodium salt (Lodronate), a bisphosphonate, is a potent antiosteolytic agent which inhibits bone resorption.Formule :CH4Cl2O6P0·2NaDegré de pureté :99.63% - ≥98%Couleur et forme :White SolidMasse moléculaire :288.86Sodium benzoate
CAS :Sodium benzoate (Benzoic acid sodium salt) is a D-Amino Acid Oxidase Inhibitor.Sodium Benzoate is a Food Preservative.Formule :C7H5NaO2Degré de pureté :99.72%Couleur et forme :White Solid CrystallineMasse moléculaire :144.10LASSBio-1135
CAS :LASSBio-1135 is an orally effective antagonist of TRPV1 and inhibitor of TNF-α production.Formule :C18H14N4Degré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :286.33SKF-86002
CAS :SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).Formule :C16H12FN3SDegré de pureté :98% - 99.85%Couleur et forme :SolidMasse moléculaire :297.351,4-Naphthoquinone
CAS :1,4-Naphthoquinone used as inhibitor for monoamine oxidase, DNA topoisomerase, and acetyltransferase.Formule :C10H6O2Degré de pureté :99.24% - 99.56%Couleur et forme :SolidMasse moléculaire :158.15Benzydamine
CAS :Benzydamine: analgesic, antipyretic, anti-inflammatory; reduces pain, swelling, aids healing post-surgery/trauma.Formule :C19H23N3ODegré de pureté :97.872% - 98.34%Couleur et forme :SolidMasse moléculaire :309.41HX 531
CAS :HX 531 is a RXR antagonist (IC50 of 18 nM).Cost-effective and quality-assured.Formule :C29H29N3O4Degré de pureté :98.59% - 99.86%Couleur et forme :SolidMasse moléculaire :483.56Malabaricone B
CAS :Malabaricone B is a Spice-derived phenolic, it induces mitochondrial damage in lung cancer cells via a p53-independent pathway.Formule :C21H26O4Degré de pureté :99.84% - 99.91%Couleur et forme :SolidMasse moléculaire :342.43(E/Z)-TG003
CAS :(E/Z)-TG003 is a potent and ATP-competitive Cdc2-like kinase (Clk) inhibitor.Formule :C13H15NO2SDegré de pureté :98% - 99.04%Couleur et forme :SolidMasse moléculaire :249.33Ref: TM-T1901
2mg42,00€5mg52,00€1mL*10mM (DMSO)52,00€10mg92,00€25mg164,00€50mg271,00€100mg399,00€200mg567,00€Tolcapone
CAS :Tolcapone (Ro 40-7592) is a catechol-O-methyltransferase inhibitor used in the therapy of Parkinson disease as adjunctive therapy in combination with levodopaFormule :C14H11NO5Degré de pureté :98.93% - 99.68%Couleur et forme :SolidMasse moléculaire :273.24Ref: TM-T6708
5mg35,00€10mg50,00€1mL*10mM (DMSO)52,00€25mg82,00€50mg92,00€100mg124,00€200mg170,00€500mg284,00€CCT007093
CAS :CCT007093 is an effective PPM1D (WIP1) inhibitor (IC50: 8.4 μM).Formule :C15H12OS2Degré de pureté :98% - 99.88%Couleur et forme :SolidMasse moléculaire :272.39Z-FA-FMK
CAS :Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.Formule :C21H23FN2O4Degré de pureté :98.84% - 99.68%Couleur et forme :SolidMasse moléculaire :386.42Isocurcumenol
CAS :1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).Formule :C15H22O2Degré de pureté :99.29% - ≥95%Couleur et forme :SolidMasse moléculaire :234.33Ref: TM-T5S0543
1mg66,00€1mL*10mM (DMSO)147,00€5mg160,00€10mg250,00€25mg425,00€50mg610,00€100mg853,00€200mg1.144,00€NVP-ADW742
CAS :NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-AblFormule :C28H31N5ODegré de pureté :96.14% - 98.70%Couleur et forme :SolidMasse moléculaire :453.583,6-Dihydroxyflavone
CAS :3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.Formule :C15H10O4Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :254.24Eprinomectin
CAS :Eprinomectin (MK-397) is an avermectin with anthelmintic and insecticidal activities.Formule :C50H75NO14Degré de pureté :97.84% - ≥95%Couleur et forme :SolidMasse moléculaire :914.13Oroxin B
CAS :Oroxin B (Hypocretin-2) has antioxidant activity.Formule :C27H30O15Degré de pureté :98.22% - 99.87%Couleur et forme :SolidMasse moléculaire :594.52BMS-1
CAS :BMS-1 is a PD-1/PD-L1 inhibitor and immunomodulator; it targets the CD274 gene product, PD-L1, linked to tumor evasion and higher mortality.
Formule :C29H33NO5Degré de pureté :99.40% - 99.81%Couleur et forme :SolidMasse moléculaire :475.58Poziotinib
CAS :Poziotinib (NOV120101)(NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM).Formule :C23H21Cl2FN4O3Degré de pureté :98.69% - 99.78%Couleur et forme :SolidMasse moléculaire :491.34Bortezomib
CAS :Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.Formule :C19H25BN4O4Degré de pureté :97.79% - >99.99%Couleur et forme :Yellow SolidMasse moléculaire :384.24Ref: TM-T2399
5mg50,00€1mL*10mM (DMSO)50,00€10mg60,00€25mg75,00€50mg92,00€100mg137,00€200mg213,00€500mg353,00€Palmatine chloride
CAS :Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.Formule :C21H22ClNO4Degré de pureté :97.9% - 99.47%Couleur et forme :SolidMasse moléculaire :387.86Madecassoside
CAS :Madecassoside (Asiaticoside A) is a pentacyclic triterpene extracted from Centella asitica (L.) with anti-inflammatory, anti-oxidative and anti-aging activitiesFormule :C48H78O20Degré de pureté :99.46% - 99.85%Couleur et forme :White PowderMasse moléculaire :975.12Ref: TM-T2813
10mg49,00€1mL*10mM (DMSO)49,00€25mg84,00€50mg120,00€100mg178,00€200mg289,00€500mg485,00€Isobavachalcone
CAS :Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury inFormule :C20H20O4Degré de pureté :98% - 99.76%Couleur et forme :SolidMasse moléculaire :324.37Dantrolene sodium hemiheptahydrate
CAS :Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calciumFormule :C14H9N4NaO5·5H2ODegré de pureté :99.72%Couleur et forme :Orange PowderMasse moléculaire :399.29UNC1215
CAS :UNC1215, a potent MBT antagonist, targets L3MBTL3 with high selectivity (IC50: 40 nM, Kd: 120 nM, 50x versus MBT family).Formule :C32H43N5O2Degré de pureté :98% - 99.04%Couleur et forme :SolidMasse moléculaire :529.72DAPT
CAS :DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active.Formule :C23H26F2N2O4Degré de pureté :98.06% - 99.81%Couleur et forme :White SolidMasse moléculaire :432.46Ref: TM-T6202
2mg38,00€5mg55,00€1mL*10mM (DMSO)56,00€10mg94,00€25mg157,00€50mg264,00€100mg358,00€200mg490,00€GYY4137
CAS :GYY4137 (GYY 4137 morpholine salt) is a novel water-soluble and slow releasing H2S donor with antihypertensive, anti-inflammatory and anticancer activity.Formule :C11H16NO2PS2·C4H9NODegré de pureté :95.54% - 99.97%Couleur et forme :SolidMasse moléculaire :376.47DIM-C-pPhCO2Me
CAS :DIM-C-pPhCO2Me is a nuclear receptor 4A1 (NR4A1) antagonist.Formule :C25H20N2O2Degré de pureté :99.55% - 99.86%Couleur et forme :SolidMasse moléculaire :380.44BMS-833923
CAS :BMS-833923 (XL-139), an orally bioavailable Smoothened antagonist, inhibits BODIPY cyclopamine binding to SMO in a dose-dependent manner (IC50: 21 nM).Formule :C30H27N5ODegré de pureté :99.47% - 99.76%Couleur et forme :SolidMasse moléculaire :473.57Ref: TM-T2299
5mg52,00€1mL*10mM (DMSO)56,00€10mg77,00€25mg120,00€50mg187,00€100mg339,00€200mg497,00€500mg790,00€TAS6417
CAS :Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.Formule :C23H20N6ODegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :396.44Ref: TM-T16996
1mg93,00€2mg117,00€5mg178,00€1mL*10mM (DMSO)203,00€10mg295,00€25mg595,00€50mg795,00€100mg1.071,00€200mg1.468,00€XL888
CAS :XL888 is an orally bioavailable Hsp90 inhibitor, blocking cell proliferation and inducing tumor regression with an IC50 of 24 nM.Formule :C29H37N5O3Degré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :503.64L-Buthionine-(S,R)-sulfoximine hydrochloride
L-Buthionine-(S,R)-sulfoximine hydrochloride is a fast, irreversible γ-GCS inhibitor that depletes glutathione. IC50: 1.9-29 μM in various tumors.Formule :C8H19ClN2O3SCouleur et forme :SolidMasse moléculaire :258.77DB1976 dihydrochloride
CAS :DB1976 dihydrochloride (DB1976 2HCl), a transcription factor PU.1 inhibitor, has potential anti-inflammatory activity for the study of metabolic dysfunction.Formule :C20H18Cl2N8SeDegré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :520.28EPZ004777 hydrochloride
CAS :EPZ004777 hydrochloride (EPZ004777 HCl) is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.Formule :C28H42ClN7O4Couleur et forme :SolidMasse moléculaire :576.13Domatinostat
CAS :Domatinostat (4SC202) is a selective class I HDAC inhibitor. Domatinostat also displays inhibitory activity against Lysine specific demethylase 1 (LSD1).Formule :C23H21N5O3SDegré de pureté :99.57% - 99.74%Couleur et forme :SolidMasse moléculaire :447.51tubuloside B
CAS :Tubuloside B from Cistanche salsa stems guards SH-SY5Y cells against TNFalpha-induced apoptosis.Formule :C31H38O16Degré de pureté :98.46% - 99.72%Couleur et forme :SolidMasse moléculaire :666.62Etomoxir sodium salt
CAS :Etomoxir sodium salt ((R)-Etomoxir sodium salt) is a carnitine palmitoyltransferase 1a (CPT-1a) inhibitor that blocks fatty acid synthesis.Formule :C15H18ClO4·NaDegré de pureté :99.34% - 99.82%Couleur et forme :SolidMasse moléculaire :320.74Ref: TM-T4535
1mg34,00€2mg40,00€5mg57,00€1mL*10mM (DMSO)63,00€10mg93,00€25mg144,00€50mg250,00€100mg409,00€200mg602,00€Urolithin A
CAS :Urolithin A is a metabolite of ellagic acid, which inhibits DNA synthesis and induces apoptosis and autophagy. Cost-effective and quality-assured.Formule :C13H8O4Degré de pureté :99.14% - 99.67%Couleur et forme :SolidMasse moléculaire :228.2Ref: TM-T7174
5mg47,00€1mL*10mM (DMSO)52,00€10mg69,00€25mg123,00€50mg177,00€100mg304,00€200mg447,00€500mg713,00€TJ191
CAS :TJ191 is a selective anti-cancer agent, targeting low TβRIII-expressing malignant T-cell leukemia/lymphoma cells.Formule :C13H21NO2SDegré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :255.38GSK2801
CAS :GSK2801 is an effective, specific and cell active acetyl-lysine competitive inhibitor of BAZ2A(Kd: 136 nM) and BAZ2B(Kd: 257 nM) bromodomains.Formule :C20H21NO4SDegré de pureté :97.78% - 99.45%Couleur et forme :SolidMasse moléculaire :371.45ASP3026
CAS :ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced Malignancies,and Positive for Anaplastic Lymphoma Kinase.Formule :C29H40N8O3SDegré de pureté :98.78% - 99.81%Couleur et forme :SolidMasse moléculaire :580.74BML-277
CAS :BML-277 (C 3742) is a selective checkpoint kinase 2 (Chk2) inhibitor.Formule :C20H14ClN3O2Degré de pureté :98.03% - ≥95%Couleur et forme :Tan SolidMasse moléculaire :363.8Ref: TM-T2033
2mg34,00€5mg49,00€1mL*10mM (DMSO)54,00€10mg80,00€25mg148,00€50mg250,00€100mg356,00€200mg522,00€
