Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(127 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(126 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(91 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5618 produits trouvés pour "Apoptose"
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HLI 373
CAS :<p>HLI373: potent Hdm2 (ubiquitin ligase) inhibitor, induces apoptosis in tumor cells, has antimalarial properties.</p>Formule :C18H23N5O2Couleur et forme :SolidMasse moléculaire :341.41n-Octyl caffeate
CAS :<p>n-Octyl caffeate demonstrates anti-cancer and apoptosis-inducing properties in highly liver-metastatic murine colon 26-L5 carcinoma cell lines.</p>Formule :C17H24O4Couleur et forme :SolidMasse moléculaire :292.37CAY10682
CAS :<p>(±)-Nutlin-3 & CAY10682 inhibit p53-Mdm2; CAY also blocks NF-κB, IKKs phosphorylation, and cancer cell growth (IC50s = 2-6 μM).</p>Formule :C30H25BrFN5OCouleur et forme :SolidMasse moléculaire :570.45PARP1-IN-31
CAS :<p>PARP1-IN-31 (compound 11f) is a PARP1 inhibitor with an IC₅₀ of 97 nM. It induces apoptosis and inhibits proliferation in lung cancer cell lines (e.g., A549).</p>Formule :C22H15ClFN3O2Degré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :407.83Tubulin inhibitor 23
CAS :<p>Potent Tubulin inhibitor 23 (IC50: 4.8 μM) induces apoptosis and has dose-dependent antiangiogenic properties, promising for leukemia research.</p>Formule :C26H23NO6SCouleur et forme :SolidMasse moléculaire :477.53PC-046
CAS :<p>PC-046, a tubulin binder, targets DPC4/SMAD4-deficient tumors, inhibits growth in vitro, and is effective in SCID mice with high oral bioavailability (71%).</p>Formule :C22H18N2O3Couleur et forme :SolidMasse moléculaire :358.39Caspase-9 Inhibitor III
CAS :<p>Caspase-9 Inhibitor III (Ac-LEHD-cmk) blocks caspase-9, protects against ischemic heart damage.</p>Formule :C24H35ClN6O9Couleur et forme :SolidMasse moléculaire :587.02PI3Kδ-IN-10
CAS :<p>PI3Kδ-IN-10 is a highly potent and orally active PI3Kδ inhibitor (IC50= 2 nM).</p>Formule :C19H16ClN9Couleur et forme :SolidMasse moléculaire :405.84IDH1 Inhibitor 9
CAS :<p>IDH1 Inhibitor 9 (compound 11S) (2, 4, 8, 10 µM) induces apoptosis and causes cell cycle arrest in the S phase in a dose-dependent manner.</p>Formule :C26H30N4O3Couleur et forme :SolidMasse moléculaire :446.54VU 0364739 hydrochloride
CAS :VU 0364739 hydrochloride (VU 0364739 HCl) is a phospholipase D2 (PLD2) inhibitor that induces apoptosis and can be used in cancer research.Formule :C26H28ClFN4O2Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :482.98GL-V9
CAS :<p>GL-V9 is an AMPK activator, protecting against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy.</p>Formule :C24H27NO5Couleur et forme :SolidMasse moléculaire :409.47pan-HER-IN-2
CAS :<p>pan-HER-IN-2 (Compound C6) is an orally active, reversible, broad-spectrum HER inhibitor that acts on EGFR (IC50: 0.72 nM), HER4 (IC50: 2.0 nM), EGFRT790M (IC50</p>Formule :C19H15BrClN5OCouleur et forme :SolidMasse moléculaire :444.71TRAF-STOP inhibitor 6877002
CAS :<p>TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.</p>Formule :C17H17NODegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :251.32BP-1-108
CAS :<p>BP-1-108 is a potent and selective STAT5 inhibitor.</p>Formule :C32H38N2O6SCouleur et forme :SolidMasse moléculaire :578.72Anticancer agent 55
CAS :<p>Potent anticancer agent inhibits cell growth, migration, induces apoptosis; promising for prostate, breast cancer studies.</p>Formule :C28H21Br2FN2O2Couleur et forme :SolidMasse moléculaire :596.294Antitumor agent-53
CAS :<p>Antitumor agent-53 hinders tumor growth, induces G2/M cell cycle arrest, and triggers apoptosis via PI3K/AKT in HGC-27 cells.</p>Formule :C24H18FN3OCouleur et forme :SolidMasse moléculaire :383.42c-Met-IN-9
CAS :<p>c-Met-IN-9 is a 4-phenoxypyridine derivative and a c-Met kinase inhibitor (IC50: 12 nM). c-Met-IN-9 induces apoptosis and shows antitumour effects.</p>Formule :C25H19F2N5O3Couleur et forme :SolidMasse moléculaire :475.45PD-1/PD-L1-IN-25
CAS :<p>"PD-1/PD-L1-IN-25 blocks PD-1/PD-L1 (IC50: 16.17 nM), boosting T-cell anti-tumor immunity, useful for cancer research."</p>Formule :C26H24ClN3O5Couleur et forme :SolidMasse moléculaire :493.94PTG-0861
CAS :<p>PTG-0861 is a selective HDAC6 inhibitor with an IC50 of 5.92 nm, promising for hematological cancer research.</p>Formule :C15H9F5N2O3Couleur et forme :SolidMasse moléculaire :360.24Benitrobenrazide
CAS :Benitrobenrazide (Hexokinase 2 inhibitor 1) is a novel orally available hexokinase 2 (HK2) inhibitor with anticancer and antitumor activity for cancer research.Formule :C14H11N3O6Degré de pureté :96.87%Couleur et forme :SolidMasse moléculaire :317.25CP 461
CAS :<p>CP 461 is a PDE2A inhibitor that promotes apoptosis in cancer cells without affecting normal cells or COX-1/2.</p>Formule :C25H22ClFN2ODegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :420.91iCRT-5
CAS :<p>iCRT-5 is a potent inhibitor of the Wnt pathway. iCRT-5 has antiproliferative activity and can be used in the study of multiple myeloma.</p>Formule :C16H17NO5S2Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :367.44TAI-1
CAS :<p>TAI-1 is a potent and specific Hec1 inhibitor, which disrupts Hec1-Nek2 protein interaction.</p>Formule :C24H21N3O3SDegré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :431.51UC-112
CAS :<p>UC-112 is a novel potent IAP inhibitor and potently inhibits cell growth in two human melanoma and two human prostate cancer cell lines (IC50=0.7-3.4 uM).</p>Formule :C22H24N2O2Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :348.44BC 11 hydrobromide
CAS :<p>The compound is a selective urokinase inhibitor (IC50 = 8.2 μM). It also inhibits clot lysis with no effect on clot formation.</p>Formule :C8H12BBrN2O2SDegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :290.97Alethine
CAS :<p>Alethine is a small antitumor compound used to treat cancers and infections, boosting T-cell cytotoxicity by raising TNFα.</p>Formule :C10H22N4O2S2Degré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :294.44(S)-Enitociclib
CAS :(S)-Enitociclib (VIP152) is a selective CDK9 inhibitor that inhibits the transcription of anti-apoptotic and pro-survival proteins.Formule :C19H18F2N4O2SDegré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :404.43Ro 90-7501
CAS :<p>Ro 90-7501, an amyloid β42 (Aβ42) protofibril and TPR-dependent PP5 inhibitor, is a novel cervical cancer cell radiosensitizer that inhibits HCMV.</p>Formule :C20H16N6Degré de pureté :97.21% - 99.72%Couleur et forme :SolidMasse moléculaire :340.38STAT3-IN-13
CAS :<p>STAT3-IN-13 is a STAT3 inhibitor with antiproliferative activity that induces apoptosis and can be used to study breast and liver cancer.</p>Formule :C21H20N6O3SDegré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :436.49CCT018159
CAS :<p>CCT018159: ATP-competitive HSP90 inhibitor, IC50 3.2 μM (human), 6.6 μM (yeast), blocks invasion, angiogenesis, induces G1 arrest and apoptosis.</p>Formule :C20H20N2O4Degré de pureté :98.78% - 99.79%Couleur et forme :SolidMasse moléculaire :352.38H2L5186303
CAS :<p>H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.</p>Formule :C26H20N2O8Degré de pureté :98.19%Couleur et forme :SolidMasse moléculaire :488.45Ro24-7429
CAS :<p>Ro24-7429: oral HIV-1 Tat antagonist, RUNX1 inhibitor with anti-HIV, antifibrotic, and anti-inflammatory properties.</p>Formule :C14H13ClN4Degré de pureté :99.29% - 99.85%Couleur et forme :SolidMasse moléculaire :272.73Vamotinib
CAS :<p>Vamotinib (PF-114) is a tyrosine kinase inhibitor with antiproliferative and antitumor activity.Vamotinib is used in the study of Alzheimer's disease.</p>Formule :C29H27F3N6ODegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :532.56AOH1160
CAS :AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA).Formule :C25H20N2O3Degré de pureté :98.46% - 99.52%Couleur et forme :SolidMasse moléculaire :396.44CMLD-2
CAS :CMLD-2 is a HuR-ARE inhibitor (Ki: 350 nM) that promotes apoptosis, has antitumor properties, and reduces thyroid cancer cell viability.Formule :C31H31NO6Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :513.58A09-003
CAS :<p>A09-003 Inhibits the proliferation of leukemia cell lines and inhibits the increase of leukemia sequence-1 protein in HI bone marrow cells.</p>Formule :C23H26N4ODegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :374.48Bomedemstat ditosylate
CAS :<p>Bomedemstat (IMG-7289) is an LSD1 inhibitor for acute myeloid leukemia, MDS, and Myelofibrosis; induces apoptosis by regulating p53, PUMA, and BCLXL.</p>Formule :C42H50FN7O8S2Degré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :864.02Tubulin inhibitor 11
CAS :<p>Potent, oral Tubulin inhibitor 11 hinders polymerization, targets Colchicine site, induces mitotic block, and apoptosis.</p>Formule :C22H23N3O3SDegré de pureté :98.32%Couleur et forme :SoildMasse moléculaire :409.5HBED
CAS :<p>HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.</p>Formule :C20H24N2O6Degré de pureté :97.35% - 98.58%Couleur et forme :SolidMasse moléculaire :388.41AZA1
CAS :<p>AZA1 (Rac1/Cdc42-IN-1) is a potent dual inhibitor of Rac1 and Cdc42.</p>Formule :C22H20N6Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :368.43BCL6-IN-7
CAS :<p>BCL6-IN-7 (BCL6 inhibitor-7) is a BCL6 corepressor-interaction inhibitor with potential antitumor activity, used in lymphoma research.</p>Formule :C18H15ClN6ODegré de pureté :99.03%Couleur et forme :SolidMasse moléculaire :366.8OR-1896
CAS :OR-1896 is a PDE III inhibitor, a vasodilator with partial anti-inflammatory properties, and can be used to study heart failure and vascular dysfunction.Formule :C13H15N3O2Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :245.28Ciglitazone
CAS :<p>Ciglitazone: potent PPARγ agonist, EC50 3 μM, oral hypoglycemic; reduces insulin, blood pressure, Th17 cells, VEGF; halts gastric cancer growth.</p>Formule :C18H23NO3SDegré de pureté :98.23% - 99.59%Couleur et forme :White Cyrstalline SolidMasse moléculaire :333.45TNIK-IN-3
CAS :<p>TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK).</p>Formule :C23H18FN3O2Degré de pureté :98.39%Couleur et forme :SolidMasse moléculaire :387.41MJN68390
CAS :<p>MJN68390 has an apparent IC50 value of 15 μM against CASP8 and shows no activity against CASP10.</p>Formule :C24H28ClN3O3Degré de pureté :98.86%Couleur et forme :SolidMasse moléculaire :441.95HBDDE
CAS :<p>HBDDE inhibits PKCα/γ (IC50: 43/50 μM), favors them over PKCδ/βI/βII, and induces neuronal apoptosis. Derived from ellagic acid.</p>Formule :C16H18O8Degré de pureté :97.94%Couleur et forme :SolidMasse moléculaire :338.31UCB-5307
CAS :<p>UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.</p>Formule :C22H21N3ODegré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :343.42Apostatin-1
CAS :<p>Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.</p>Formule :C19H27N3OSDegré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :345.5CBS9106
CAS :<p>CBS9106 (SL-801) is a CRM1 inhibitor with CRM1-degrading and anti-tumor activity that inhibits CRM1-dependent nuclear export.</p>Formule :C18H21ClF3N3O3Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :419.83SB 699551 dihydrochloride
CAS :<p>SB 699551 dihydrochloride is a 5-ht5a receptor antagonist.</p>Formule :C34H47Cl2N3ODegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :584.66
