Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(94 produits)
- CDK(500 produits)
- Arrêt du cycle cellulaire(4 produits)
- Chk(42 produits)
- DYRK(48 produits)
- Dynamine(23 produits)
- Ferroptose(215 produits)
- HSP(169 produits)
- Intégrine(224 produits)
- Kinésine(66 produits)
- LIM Kinase(19 produits)
- Microtubules associés(261 produits)
- PKC(102 produits)
- PLK(28 produits)
- ROCK(70 produits)
- Rho(2 produits)
- Wee1(15 produits)
- c-Myc(69 produits)
Affichez 10 plus de sous-catégories
3477 produits trouvés pour "Cycle cellulaire/point de contrôle"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
PD 407824
CAS :<p>PD 407824 is a chemical BMP sensitiser that promotes increased cellular sensitivity to subthreshold amounts of BMP4.PD 407824 is a potent inhibitor of the checkpoint kinases Chk1 and WEE1 (IC50s: 47 and 97 nM, respectively).</p>Formule :C20H12N2O3Degré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :328.322'-O-Methyl-5-iodouridine
CAS :<p>2'-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a</p>Formule :C10H13IN2O6Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :384.12TG003
CAS :<p>TG003 is a Clk1/Sty inhibitor that inhibits Clk1 and Clk4, suppresses cancer cell growth, and induces apoptosis.</p>Formule :C13H15NO2SDegré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :249.33Talotrexin
CAS :<p>Talotrexin (PT523), a nonpolyglutamatable antifolate analog of Aminopterin, inhibits DHFR and RFC, targeting tumor growth.</p>Formule :C27H27N9O6Couleur et forme :SolidMasse moléculaire :573.56kb-NB77-78
CAS :<p>kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).</p>Formule :C18H25NO3SiDegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :331.48Rabusertib
CAS :<p>Rabusertib (IC-83) is a chk1 inhibitor in trials for various cancers, including pancreatic and non-small cell lung cancer.</p>Formule :C18H22BrN5O3Degré de pureté :98.86% - 99.87%Couleur et forme :SolidMasse moléculaire :436.3Trilaciclib
CAS :<p>Trilaciclib is a short-acting, orally effective CDK4/6 inhibitor with IC₅₀ values of 1 nM and 4 nM respectively. enhances antitumour immunity.</p>Formule :C24H30N8ODegré de pureté :99.624%Couleur et forme :SolidMasse moléculaire :446.55Hesperadin
CAS :<p>Hesperadin(IC50=250 nM) effectively inhibits Aurora B.</p>Formule :C29H32N4O3SDegré de pureté :98.04% - 99.44%Couleur et forme :SolidMasse moléculaire :516.65Mps1-IN-3 hydrochloride
<p>Mps1-IN-3 HCl: potent Mps1 inhibitor (IC50: 50 nM), hampers glioblastoma growth, enhances vincristine efficacy in vivo.</p>Formule :C26H32ClN7O4SCouleur et forme :SolidMasse moléculaire :574.09NSC 617145
CAS :<p>NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent</p>Formule :C13H10Cl4N2O4Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :400.04GDC0575 monohydrochloride
CAS :<p>GDC0575 (ARRY575), a potent Chk1 inhibitor, IC50 1.2nM, disrupts cell cycle arrest, allowing DNA repair before mitosis.</p>Formule :C16H21BrClN5ODegré de pureté :97.85%Couleur et forme :SolidMasse moléculaire :414.73AT-9283 HCl
CAS :<p>AT-9283, a multi-targeted kinase inhibitor, is used potentially for the treatment of multiple myeloma.</p>Formule :C19H24ClN7O2Couleur et forme :SolidMasse moléculaire :417.89Dasabuvir sodium
CAS :<p>Dasabuvir sodium (ABT-333) inhibits HCV NS5B polymerase, targeting genotypes 1a (EC50: 7.7 nM) and 1b (EC50: 1.8 nM).</p>Formule :C26H26N3NaO5SCouleur et forme :SolidMasse moléculaire :515.56Phosphonoformic acid trisodium salt hexa
CAS :<p>Phosphonoformic acid trisodium salt hexa (Sodium phosphonatoformate hexahydrate) is an antiviral drug for the treatment of CMV retinitis.</p>Formule :CH12Na3O11PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :300.03E7820
CAS :<p>E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).</p>Formule :C17H12N4O2SDegré de pureté :98.31% - 99.11%Couleur et forme :SolidMasse moléculaire :336.37EN4
CAS :<p>EN4 (EN4 MYC inhibitor) MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC.</p>Formule :C25H24N2O4Degré de pureté :98.51%Couleur et forme :SolidMasse moléculaire :416.47CKI-7 free base
CAS :<p>CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.</p>Formule :C11H12ClN3O2SCouleur et forme :SolidMasse moléculaire :285.75MLS000532223
CAS :<p>MLS000532223 is a selectiveRho family GTPases inhibitor(EC50 : 16 μM to 120 μM).</p>Formule :C15H9NO3Degré de pureté :98.6%Couleur et forme :SolidMasse moléculaire :251.24TH-263
CAS :<p>TH-263 is inactive toward both LIMK1 and LIMK2 and thus can be used as negative control for TH-257, and is a diaryl sulfonamide derivative.</p>Formule :C21H20N2O3SDegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :380.46iRGD peptide
CAS :<p>iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.</p>Formule :C35H57N13O14S2Degré de pureté :98.77%Couleur et forme :SolidMasse moléculaire :948.04Orbofiban
CAS :<p>Orbofiban, an orally administered antagonist of the platelet GPIIb/IIIa receptor, effectively inhibits platelet aggregation.</p>Formule :C17H23N5O4Couleur et forme :SolidMasse moléculaire :361.4APTO-253 HCl
CAS :<p>APTO-253 (LOR-253/LT-253) is a small-molecule MTF-1 inhibitor with antitumor properties, reducing cyclin D1, hypoxia, and angiogenesis gene expression.</p>Formule :C22H15ClFN5Couleur et forme :SolidMasse moléculaire :403.84HA-100 hydrochloride
CAS :<p>HA-100 hydrochloride inhibits protein kinases PKG, PKA, PKC, MLC-kinase (IC50: 4-240 μM) and ROCK.</p>Formule :C13H16ClN3O2SCouleur et forme :SolidMasse moléculaire :313.8BMH-21
CAS :<p>BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.</p>Formule :C21H20N4O2Degré de pureté :99.47% - 99.84%Couleur et forme :SolidMasse moléculaire :360.41S-trityl-L-Cysteine
CAS :<p>S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5</p>Formule :C22H21NO2SDegré de pureté :97.02%Couleur et forme :Almost White To Light Yellow Granular PowderMasse moléculaire :363.47Apcin
CAS :<p>Apcin: potent APC/C(Cdc20) E3 ligase inhibitor, blocks substrate recognition & mitosis, synergizes with Ts-Arg-OMe.</p>Formule :C13H14Cl3N7O4Degré de pureté :96.74%Couleur et forme :SolidMasse moléculaire :438.65CHR-6494
CAS :<p>CHR-6494 is a haspin inhibitor that inhibits histone H3T3 phosphorylation (IC50: 2 nM).</p>Formule :C16H16N6Degré de pureté :98.78%Couleur et forme :SolidMasse moléculaire :292.34Palmatine chloride
CAS :<p>Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.</p>Formule :C21H22ClNO4Degré de pureté :97.9% - 99.47%Couleur et forme :SolidMasse moléculaire :387.857Datelliptium chloride hydrochloride
CAS :<p>Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities.</p>Formule :C23H29Cl2N3ODegré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :434.4CCT 137690
CAS :<p>CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).</p>Formule :C26H31BrN8ODegré de pureté :98.51% - 99.89%Couleur et forme :SolidMasse moléculaire :551.48AZD-7762
CAS :<p>AZD-7762, an effective and specific inhibitor of Chk1（IC50=5 nM）, is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.</p>Formule :C17H19FN4O2SDegré de pureté :98.96% - 99.19%Couleur et forme :SolidMasse moléculaire :362.42Netarsudil free base
CAS :<p>Netarsudil (AR-11324), a ROCK inhibitor, treats glaucoma by increasing eye outflow and lowering IOP, with mild hyperemia as a side effect.</p>Formule :C28H27N3O3Couleur et forme :SolidMasse moléculaire :453.53NG 52
CAS :<p>NG 52 (NG-52) is a cell-permeable, reversible, and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p and the related Pho85p kinase.</p>Formule :C16H19ClN6ODegré de pureté :98% - 99.34%Couleur et forme :SolidMasse moléculaire :346.81LY3143921
CAS :<p>LY3143921 ((S)-Example 2) is an orally active inhibitor of CDC7 kinase with broad in vitro anticancer activity [1].</p>Formule :C16H12FN5OCouleur et forme :SolidMasse moléculaire :309.3RCM-1
CAS :<p>RCM-1 is an inhibitor of FOXM1.</p>Formule :C20H12N2OS4Degré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :424.58IRE1α kinase-IN-1
CAS :<p>IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM.</p>Formule :C26H26ClFN8Degré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :504.99Levomefolate calcium
CAS :<p>Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.</p>Formule :C20H23CaN7O6Degré de pureté :97.35%Couleur et forme :Off-White To Pale Yellow SolidMasse moléculaire :497.52Carotegrast methyl
CAS :<p>Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.</p>Formule :C28H26Cl2N4O5Degré de pureté :99.26% - 99.72%Couleur et forme :SolidMasse moléculaire :569.44Brr2-IN-3
CAS :<p>Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa.</p>Formule :C24H20N4O3SDegré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :444.51Avotaciclib trihydrochloride
CAS :<p>Avotaciclib trihydrochloride (BEY1107) is an oral CDK1 inhibitor targeting advanced pancreatic cancer.</p>Formule :C13H14Cl3N7ODegré de pureté :99%Couleur et forme :SolidMasse moléculaire :390.653'-Deoxyguanosine
CAS :<p>3'-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors.</p>Formule :C10H13N5O4Degré de pureté :98.85% - 98.96%Couleur et forme :SolidMasse moléculaire :267.24Tempo
CAS :<p>Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a</p>Formule :C9H18NODegré de pureté :98.35%Couleur et forme :Orange Crystals Or PowderMasse moléculaire :156.25AI-10-49
CAS :<p>AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.</p>Formule :C30H22F6N6O5Degré de pureté :97.14%Couleur et forme :SolidMasse moléculaire :660.526-Thioinosine
CAS :<p>6-Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent.</p>Formule :C10H12N4O4SDegré de pureté :97.74%Couleur et forme :SolidMasse moléculaire :284.29Deoxythymidine triphosphate
CAS :<p>Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.</p>Formule :C10H14N2Na3O14P3Degré de pureté :99.78%Couleur et forme :White Amorphous PowderMasse moléculaire :548.11PKD-IN-1 dihydrochloride (956121-30-5 free base)
CAS :<p>CRT0066101 dihydrochloride is an inhibitor of PKD.</p>Formule :C18H21Cl3N4ODegré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :415.75Brequinar
CAS :<p>Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.</p>Formule :C23H15F2NO2Degré de pureté :99.1% - 99.57%Couleur et forme :SolidMasse moléculaire :375.37Pyridostatin hydrochloride
CAS :<p>Pyridostatin hydrochloride stabilizes G-quadruplex DNA (Kd=490nM), inhibits cancer cell growth, and reduces SRC in breast cancer.</p>Formule :C31H37Cl5N8O5Couleur et forme :SolidMasse moléculaire :778.94BMS-8
CAS :<p>BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers.</p>Formule :C27H28BrNO3Degré de pureté :98.88%Couleur et forme :SolidMasse moléculaire :494.42Mps1-IN-1 dihydrochloride
CAS :<p>Mps1-IN-1 dihydrochloride, a potent ATP-competitive inhibitor of Mps1 kinase, exhibits an IC50 of 367 nM.</p>Formule :C28H35Cl2N5O4SCouleur et forme :SolidMasse moléculaire :608.58UNC10217938A
CAS :<p>UNC10217938A is a 3-deazapteridine analog, has strong oligonucleotide enhancing effects.</p>Formule :C26H28N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :456.54LY3405105
CAS :<p>LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-</p>Formule :C26H39N7O3Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :497.63Barasertib-HQPA
CAS :<p>Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.</p>Formule :C26H30FN7O3Degré de pureté :98.43% - 99.29%Couleur et forme :SolidMasse moléculaire :507.56N6,N6-Dimethyladenosine
CAS :<p>N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.</p>Formule :C12H17N5O4Degré de pureté :98.79%Couleur et forme :White PowderMasse moléculaire :295.29Proguanil
CAS :<p>Proguanil (Chloroguanide) is a prophylactic antimalarial drug that acts primarily through its active metabolite, Cycloguanil, which inhibits the DHFR enzyme .</p>Formule :C11H16ClN5Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :253.73FIT-039
CAS :<p>FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).</p>Formule :C17H18FN3SDegré de pureté :98.61%Couleur et forme :SolidMasse moléculaire :315.41NVP-LCQ195
CAS :<p>NVP-LCQ195 (LCQ-195) (AT9311) is a potent inhibitor of CDK1, CDK2, CDK3 and CDK5 (IC50: 1-42 nM).</p>Formule :C17H19Cl2N5O4SDegré de pureté :99.56% - 99.85%Couleur et forme :SolidMasse moléculaire :460.33JSH-150
CAS :<p>JSH-150 is a highly selective CDK9 inhibitor(IC50 : 1 nM).</p>Formule :C24H33ClN6O2SDegré de pureté :99.96% - 99.96%Couleur et forme :SolidMasse moléculaire :505.08Cilengitide
CAS :<p>Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.</p>Formule :C27H40N8O7Degré de pureté :98% - 99.8%Couleur et forme :SolidMasse moléculaire :588.66Atuveciclib
CAS :<p>Atuveciclib Racemate is an oral CDK9 inhibitor with a 13 nM IC50, targeting P-TEFb/CDK9 selectively.</p>Formule :C18H18FN5O2SDegré de pureté :98.8%Couleur et forme :SolidMasse moléculaire :387.432-Chloroadenosine
CAS :<p>2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectively</p>Formule :C10H12ClN5O4Degré de pureté :99.23%Couleur et forme :White PowderMasse moléculaire :301.69Fosifloxuridine nafalbenamide
CAS :<p>Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.</p>Formule :C29H29FN3O9PDegré de pureté :95.87%Couleur et forme :SolidMasse moléculaire :613.53GSK461364
CAS :<p>GSK461364 (GSK461364A)(Ki=2.2 nM) inhibits purified Plk1 .The specificity of GSK461364 for Plk1 is more than 1000-fold over Plk2/3.</p>Formule :C27H28F3N5O2SDegré de pureté :99% - 99.73%Couleur et forme :SolidMasse moléculaire :543.6ILK-IN-2
CAS :<p>ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.</p>Formule :C30H30F3N5ODegré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :533.593-AP
CAS :<p>3-AP (Triapine) is a novel inhibitor of the M2 subunit of ribonucleotide reductase (RR).</p>Formule :C7H9N5SDegré de pureté :97.33% - 99.87%Couleur et forme :SolidMasse moléculaire :195.24CW-069
CAS :<p>CW-069 (IC50=75 μM）, an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.</p>Formule :C23H21IN2O3Degré de pureté :97.52% - 99.52%Couleur et forme :SolidMasse moléculaire :500.33CCG-203971
CAS :<p>CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM.</p>Formule :C23H21ClN2O3Degré de pureté :98.82% - 99.50%Couleur et forme :SolidMasse moléculaire :408.88SP-146
<p>SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).</p>Formule :C25H20FN7ODegré de pureté :97.82%Couleur et forme :SolidMasse moléculaire :453.47LY2880070
CAS :<p>LY2880070 is a new checkpoint kinase 1 (CHK1) inhibitor for cancer therapy.</p>Formule :C19H23N7O2Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :381.43BMS-1001
CAS :<p>BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).</p>Formule :C35H34N2O7Degré de pureté :98.43%Couleur et forme :SolidMasse moléculaire :594.7WNK-IN-11
CAS :<p>WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)</p>Formule :C21H21Cl2N5OSDegré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :462.4Bractoppin
CAS :<p>Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits</p>Formule :C25H23FN4ODegré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :414.47DMT-2′Fluoro-dU Phosphoramidite
CAS :<p>DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.</p>Formule :C39H46FN4O8PDegré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :748.78BMS-5
CAS :<p>BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively.</p>Formule :C17H14Cl2F2N4OSDegré de pureté :98.01% - 99.88%Couleur et forme :SolidMasse moléculaire :431.292′-Deoxy-2′-fluoroguanosine
CAS :<p>2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM).</p>Formule :C10H12FN5O4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :285.23AZD-5597
CAS :<p>AZD-5597 ((S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(methylamino)pyrrolidin-1-yl)methanone) is a potent</p>Formule :C23H28FN7ODegré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :437.51WR99210 hydrochloride(47326-86-3 free base)
CAS :<p>WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target.</p>Formule :C14H19Cl4N5O2Degré de pureté :97.77% - 99.8%Couleur et forme :SolidMasse moléculaire :431.14Saccharin 1-methylimidazole
CAS :<p>Saccharin 1-methylimidazole (SMI) is a general-purpose activator used for DNA and RNA synthesis.</p>Formule :C7H5NO3S·C4H6N2Degré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :265.29LDC-4297 HCl (1453834-21-3(free base))
<p>LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.</p>Formule :C23H29ClN8ODegré de pureté :100%Couleur et forme :SolidMasse moléculaire :469.02Ispinesib
CAS :<p>Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic</p>Formule :C30H33ClN4O2Degré de pureté :98% - 99.09%Couleur et forme :SolidMasse moléculaire :517.06Bonafton
CAS :<p>Bonafton (Bonaphthone) is an antiviral agent.</p>Formule :C10H5BrO2Degré de pureté :97.16%Couleur et forme :SolidMasse moléculaire :237.053-Deazauridine
CAS :<p>3-Deazauridine (NSC-126849), a uridine analog, blocks CTP synthesis by competing with CTP synthetase.</p>Formule :C10H13NO6Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :243.21Calcium N5-methyltetrahydrofolate
CAS :<p>Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and</p>Formule :C20H23CaN7O6Degré de pureté :99.41%Couleur et forme :SolidMasse moléculaire :497.51CC-671
CAS :<p>CC-671 is a dual TTK protein kinase (IC50: 0.005 μM) /CLK2 (IC50: 0.006 μM) inhibitor.</p>Formule :C28H28N6O4Degré de pureté :98.66% - 98.8%Couleur et forme :SolidMasse moléculaire :512.56Arg-Gly-Asp TFA (99896-85-2(free base))
<p>Arg-Gly-Asp TFA (RGD, 99896-85-2) is a tripeptide that promotes cell adhesion and integrin binding.</p>Formule :C14H23F3N6O8Degré de pureté :99.2% - ≥98%Couleur et forme :SolidMasse moléculaire :460.36Trifluridine/tipiracil hydrochloride mixture
CAS :<p>Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in a</p>Formule :C29H34Cl2F6N8O12Degré de pureté :98% - 99.79%Couleur et forme :SolidMasse moléculaire :871.53Vidofludimus
CAS :<p>Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).</p>Formule :C20H18FNO4Degré de pureté :98.33% - 99.58%Couleur et forme :SolidMasse moléculaire :355.36EHT 1864 2HCl
CAS :<p>EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3. Cost effective and quality assured.</p>Formule :C25H29Cl2F3N2O4SDegré de pureté :98.39% - 99.42%Couleur et forme :SolidMasse moléculaire :581.47Danofloxacin
CAS :<p>Danofloxacin (Danofloxacin free base) is a fluoroquinolone antibiotic used in veterinary medicine.</p>Formule :C19H20FN3O3Degré de pureté :99.77% - 99.8%Couleur et forme :SolidMasse moléculaire :357.38GPRP acetate (67869-62-9 free base)
CAS :<p>GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex.</p>Formule :C20H35N7O7Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :485.536-O-Methyl Guanosine
CAS :<p>6-O-Methyl Guanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line.</p>Formule :C11H15N5O5Degré de pureté :97.5%Couleur et forme :SolidMasse moléculaire :297.27MLN0905
CAS :<p>MLN0905 (PLK1 Inhibitor) is an effective PLK1 inhibitor(IC50=2 nM).</p>Formule :C24H25F3N6SDegré de pureté :97.17% - 98%Couleur et forme :SolidMasse moléculaire :486.56Levoleucovorin Calcium
CAS :<p>Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.</p>Formule :C20H21N7O7·CaDegré de pureté :99.07% - ≥98%Couleur et forme :White Crystalline PowderMasse moléculaire :511.5BMS-3
CAS :<p>BMS-3 is a potent LIMK inhibitor with IC50s of 5 nM and 6 nM for LIMK1 and LIMK2, respectively.</p>Formule :C17H12Cl2F2N4OSDegré de pureté :99.31% - 99.81%Couleur et forme :SolidMasse moléculaire :429.27Fanotaprim
CAS :<p>Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor.</p>Formule :C19H22N8ODegré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :378.43TR-14035
CAS :<p>TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).</p>Formule :C24H21Cl2NO5Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :474.33EOAI3402143
CAS :<p>EOAI3402143 inhibits Usp9x and Usp24 activity, increases tumor cell apoptosis.</p>Formule :C25H28Cl2N4O3Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :503.42LY3177833
CAS :<p>LY3177833 is an Cdc7 kinase inhibitor (IC50 : 3.3 nM)</p>Formule :C16H12FN5ODegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :309.3LXW7
CAS :<p>LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (</p>Formule :C29H48N12O12S2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :820.89AT9283
CAS :<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Formule :C19H23N7O2Degré de pureté :99.83% - 99.98%Couleur et forme :SolidMasse moléculaire :381.43
