Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(94 produits)
- CDK(500 produits)
- Arrêt du cycle cellulaire(4 produits)
- Chk(42 produits)
- DYRK(48 produits)
- Dynamine(23 produits)
- Ferroptose(215 produits)
- HSP(169 produits)
- Intégrine(224 produits)
- Kinésine(66 produits)
- LIM Kinase(19 produits)
- Microtubules associés(261 produits)
- PKC(102 produits)
- PLK(28 produits)
- ROCK(70 produits)
- Rho(2 produits)
- Wee1(15 produits)
- c-Myc(69 produits)
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3477 produits trouvés pour "Cycle cellulaire/point de contrôle"
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MSC2530818
CAS :<p>MSC2530818 is an effective, selective and orally available CDK8 inhibitor (IC50: 2.6 nM).</p>Formule :C18H17ClN4ODegré de pureté :98.93%Couleur et forme :SolidMasse moléculaire :340.81GDC-0575
CAS :<p>GDC-0575 (ARRY-575) is a highly-selective oral small-molecule Chk1 inhibitor(IC50 of 1.2 nM).</p>Formule :C16H20BrN5ODegré de pureté :≥95%Couleur et forme :SolidMasse moléculaire :378.27TCS7010
CAS :<p>TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.</p>Formule :C31H31ClFN7O2Degré de pureté :98.49% - 99.62%Couleur et forme :SolidMasse moléculaire :588.07HA-100
CAS :<p>HA-100 is an inhibitor of protein kinase</p>Formule :C13H15N3O2SDegré de pureté :99.44%Couleur et forme :Pale Yellow Crystalline SolidMasse moléculaire :277.34Zoliflodacin
CAS :<p>Zoliflodacin (ETX0914) (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor.</p>Formule :C22H22FN5O7Degré de pureté :99.82% - 99.93%Couleur et forme :SolidMasse moléculaire :487.44BS-181 dihydrochloride
CAS :<p>BS-181 dihydrochloride: Potent CDK7 inhibitor (IC50: 21 nM), less effective on CDK2/5/9, no impact on CDK1/4/6, halts cancer cell growth, triggers apoptosis.</p>Formule :C22H34Cl2N6Couleur et forme :SolidMasse moléculaire :453.46GNF2133 hydrochloride
CAS :<p>GNF2133 hydrochloride: selective oral DYRK1A inhibitor (IC50: 0.0062 μM), boosts β-cell growth and insulin, potential for type 1 diabetes research.</p>Formule :C24H31ClN6O2Couleur et forme :SolidMasse moléculaire :471.06-Thio-2'-Deoxyguanosine
CAS :<p>6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.</p>Formule :C10H13N5O3SDegré de pureté :97.52%Couleur et forme :SolidMasse moléculaire :283.31POL1-IN-1
CAS :<p>POL1-IN-1 (Compound 3A) 是一种RNA 聚合酶 1 POL1抑制剂，IC50值低于 0.5 uM。 它能有效抑制A375恶性黑色素瘤细胞系中RNA 聚合酶I 的转录。</p>Formule :C21H20N6Degré de pureté :98% - 98.01%Couleur et forme :SolidMasse moléculaire :356.42Ocifisertib(CFI-400945 free base)
CAS :<p>Ocifisertib (CFI-400945 free base) is a potent, selective and orally active inhibitor of polo-like kinase 4.Cost-effective and quality-assured.</p>Formule :C33H34N4O3Degré de pureté :98.53% - 99.04%Couleur et forme :SolidMasse moléculaire :534.65N1-Methylpseudouridine
CAS :<p>N1-Methylpseudouridine (1-Methylpseudouridine) is a methylpseudouridine and enhances translation through eIF2α-dependent and independent mechanisms by</p>Formule :C10H14N2O6Degré de pureté :98.95% - 99.88%Couleur et forme :SolidMasse moléculaire :258.23LJI308
CAS :<p>LJI308 is a potent, and pan-RSK (p90 ribosomal S6 kinase) inhibitor with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.</p>Formule :C21H18F2N2O2Degré de pureté :99.73% - 99.87%Couleur et forme :SolidMasse moléculaire :368.38Acelarin
CAS :<p>Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.</p>Formule :C25H27F2N4O8PDegré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :580.47CYC-116
CAS :<p>CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active</p>Formule :C18H20N6OSDegré de pureté :97.36% - 97.59%Couleur et forme :SolidMasse moléculaire :368.46THZ1
CAS :<p>THZ1 (CDK7 inhibitor) is a selective inhibitor of CDK7, binding to the Cys residue located at the outer end of the classical kinase domain. Cost-effective and quality-assured.</p>Formule :C31H28ClN7O2Degré de pureté :95.09% - 99.27%Couleur et forme :SolidMasse moléculaire :566.05PFM01
CAS :<p>PFM01 inhibits MRE11 enzyme, steering DSBR towards NHEJ over HR.</p>Formule :C14H15NO2S2Degré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :293.4Simeprevir
CAS :<p>Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.</p>Formule :C38H47N5O7S2Degré de pureté :99.45% - 99.92%Couleur et forme :SolidMasse moléculaire :749.94Aurora kinase inhibitor-3
CAS :<p>Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK,</p>Formule :C21H18F3N5ODegré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :413.4GW406108X(Z/E)
CAS :<p>GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .</p>Formule :C20H11Cl2NO4Degré de pureté :98.23%Couleur et forme :SolidMasse moléculaire :400.21Dalpiciclib
CAS :<p>Dalpiciclib (SHR-6390) selectively inhibits CDK4/6 (IC50: 12.4/9.9 nM), is orally available, and impedes esophageal cancer growth.</p>Formule :C25H30N6O2Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :446.54MLN8054
CAS :<p>MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.</p>Formule :C25H15ClF2N4O2Degré de pureté :98.07% - 98.26%Couleur et forme :SolidMasse moléculaire :476.86A-205804
CAS :<p>A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.</p>Formule :C15H12N2OS2Degré de pureté :98.07% - 98.52%Couleur et forme :SolidMasse moléculaire :300.4TH588 hydrochloride
CAS :<p>TH588 hydrochloride is first-in-class inhibitor of nudix hydrolase family that selectively and effectively bind and inhibit the MTH1 with IC50 value of 5 nM.</p>Formule :C13H13Cl3N4Couleur et forme :SolidMasse moléculaire :331.63Methotrexate metabolite
CAS :<p>DAMPA, active metabolite of Methotrexate, is a chemotherapeutic and immunosuppressive folic acid antagonist.</p>Formule :C15H15N7O2Degré de pureté :95.60% - 97.59%Couleur et forme :SolidMasse moléculaire :325.33SBC-115337
CAS :<p>SBC-115337 is a PCSK9 inhibitor.</p>Formule :C29H19N3O4Degré de pureté :99.41%Couleur et forme :SolidMasse moléculaire :473.48BTYNB
CAS :<p>BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1. MDK6620 downregulates β-TrCP1 mRNA and reduces activation of NF-κB.</p>Formule :C12H9BrN2OSDegré de pureté :≥95%Couleur et forme :SolidMasse moléculaire :309.18Y16 acetate(429653-73-6 free base)
<p>Y16 acetate(429653-73-6 free base) is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoA</p>Formule :C51H74N14O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1091.24Briciclib
CAS :<p>Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.</p>Formule :C19H23O10PSDegré de pureté :98% - 99.84%Couleur et forme :SolidMasse moléculaire :474.42Nemorubicin
CAS :<p>Nemorubicin (PNU 152243) is a unique doxorubicin variant with varied antitumor action, metabolism, and toxicity, effective against resistant tumors.</p>Formule :C32H37NO13Degré de pureté :97.4%Couleur et forme :SolidMasse moléculaire :643.64Amenamevir
CAS :<p>Amenamevir (ASP2151) is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (EC50: 14 ng/mL</p>Formule :C24H26N4O5SDegré de pureté :99.00% - 99.86%Couleur et forme :SolidMasse moléculaire :482.55Garenoxacin mesylate hydrate
CAS :<p>Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strains</p>Formule :C23H20F2N2O4·CH4O3S·H2ODegré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :540.53CCT245737
CAS :<p>CCT245737 is an orally active, selective Chk1 inhibitor, and is >1,000-fold selective over CHK2 and CDK1.Cost-effective and quality-assured.</p>Formule :C16H16F3N7ODegré de pureté :98.06% - 99.69%Couleur et forme :SolidMasse moléculaire :379.34IMP-1088
CAS :<p>IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.</p>Formule :C25H29F2N5ODegré de pureté :98.48% - 99.52%Couleur et forme :SolidMasse moléculaire :453.53TAK-960 monohydrochloride
CAS :<p>TAK-960 monohydrochloride, an oral compound, inhibits PLK1 (IC50=0.8 nM), PLK2, PLK3, stunts cancer cell growth, and is effective in tumor models.</p>Formule :C27H35ClF3N7O3Couleur et forme :SolidMasse moléculaire :598.07Pritelivir
CAS :<p>Pritelivir (BAY 57-1293) (BAY 57-1293) is a potent helicase-primase inhibitor with active against HSV-1 and HSV-2 (IC50: 20 nM).</p>Formule :C18H18N4O3S2Degré de pureté :97.96% - 99.42%Couleur et forme :SolidMasse moléculaire :402.49Senexin A
CAS :<p>Senexin A is an effective and selective CDK8 inhibitor that also inhibits CDK19 with Kd values of 0.83 microns and 0.31 microns, respectively.</p>Formule :C17H14N4Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :274.32SEL120-34A HCl
CAS :<p>SEL120-34A HCl is a selective, orally available and ATP-competitive inhibitor of CDK8(CDK8/CycC and CDK19/CycC with IC50s of 4.4 nM and 10.4 nM , respectively</p>Formule :C15H19Br2ClN4Degré de pureté :98.13% - 98.47%Couleur et forme :SolidMasse moléculaire :450.6FEN1-IN-SC13
CAS :<p>FEN1-IN-SC13 is a potent inhibitor of DNA fragmentation endonuclease 1 (FEN1)</p>Formule :C24H23N3O3SDegré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :433.52Palbociclib
CAS :<p>Palbociclib is an oral CDK4/6 inhibitor, halts Rb phosphorylation, arrests cell cycle, and curbs tumor growth.</p>Formule :C24H29N7O2Degré de pureté :98% - 99.9%Couleur et forme :SolidMasse moléculaire :447.53LY2334737
CAS :<p>LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.</p>Formule :C17H25F2N3O5Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :389.39MLS-573151
CAS :<p>MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).</p>Formule :C21H19N3O2SDegré de pureté :98.80%Couleur et forme :SolidMasse moléculaire :377.46Dalpiciclib hydrochloride
<p>Dalpiciclib (SHR-6390) HCl is an oral CDK4/6 inhibitor with IC50s of 12.4/9.9 nM, an antitumor for breast and esophageal cancers.</p>Formule :C25H31ClN6O2Couleur et forme :SolidMasse moléculaire :483.01SBC-110736
CAS :<p>SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor</p>Formule :C26H27N3O2Degré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :413.51DMTr-LNA-5MeU-3-CED-phosphoramidite
CAS :<p>DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.</p>Formule :C41H49N4O9PDegré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :772.82FOY 251
CAS :<p>FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.</p>Formule :C17H19N3O7SDegré de pureté :97.11% - 99.33%Couleur et forme :SolidMasse moléculaire :409.415-BrdU
CAS :<p>5-BrdU (Broxuridine) is a nucleoside analogue, detect proliferating cells and compete with thymidine for incorporation into DNA. High-Quality, Low-Cost!</p>Formule :C9H11BrN2O5Degré de pureté :99.54% - 99.87%Couleur et forme :Crystals From Absolute Ethanol Physical Description White Crystalline Powder (Ntp 1992)Masse moléculaire :307.1TAK-960 hydrochloride
CAS :<p>TAK-960 hydrochloride is an oral, potent PLK1 inhibitor with IC50 of 0.8 nM, effective against various tumor cells and xenografts.</p>Formule :C27H35ClF3N7O3Couleur et forme :SolidMasse moléculaire :598.06BMS-1166
CAS :<p>BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.</p>Formule :C36H33ClN2O7Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :641.11SCH900776
CAS :<p>SCH900776 (MK-8776) is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities.</p>Formule :C15H18BrN7Degré de pureté :96.69% - 99.6%Couleur et forme :SolidMasse moléculaire :376.25TH5427 hydrochloride
CAS :<p>TH5427 HCl inhibits NUDT5 with 29 nM IC50; 690x more selective over MTH1; blocks ATP in breast cancer cells, hindering growth.</p>Formule :C20H21Cl3N8O3Couleur et forme :SolidMasse moléculaire :527.79Cucurbitacin B
CAS :<p>Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.</p>Formule :C32H46O8Degré de pureté :97.1% - 99.33%Couleur et forme :SolidMasse moléculaire :558.7Ibezapolstat
CAS :<p>Ibezapolstat (ACX-362E) is an antibiotic with antibacterial activity that inhibits Clostridium difficile.</p>Formule :C18H20Cl2N6O2Degré de pureté :98% - 99.429%Couleur et forme :SolidMasse moléculaire :423.3RI-1
CAS :<p>RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).</p>Formule :C14H11Cl3N2O3Degré de pureté :99.3% - 99.62%Couleur et forme :SolidMasse moléculaire :361.61Y16
CAS :<p>Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG with a Kd of 76 nM.Cost-effective and quality-assured.</p>Formule :C24H20N2O3Degré de pureté :98.26% - 99.32%Couleur et forme :SolidMasse moléculaire :384.43TMPyP4 tosylate
CAS :<p>TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.</p>Formule :C72H66N8O12S4Degré de pureté :98.61% - 99.85%Couleur et forme :SolidMasse moléculaire :1363.6RNase L-IN-2
CAS :<p>RNase L-IN-2 activates RNase L at 22 uM, has antiviral effects on various RNA viruses, non-toxic at effective levels.</p>Formule :C16H14N2O2SDegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :298.365'-Deoxy-5-fluorocytidine
CAS :<p>5'-Deoxy-5-fluorocytidine is an intermediate metabolite of the DNA synthesis inhibitor capecitabine.</p>Formule :C9H12FN3O4Degré de pureté :99.67%Couleur et forme :White SolidMasse moléculaire :245.21PNU112455A hydrochloride
CAS :<p>PNU112455A hydrochloride is an ATP site competetive inhibitor of CDK2 and CDK5,binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.</p>Formule :C10H12ClN5O2SDegré de pureté :98.58% - 99.22%Couleur et forme :SolidMasse moléculaire :301.75Tirofiban hydrochloride monohydrate
CAS :<p>Tirofiban（MK383） hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.</p>Formule :C22H39ClN2O6SDegré de pureté :98.81% - >99.99%Couleur et forme :White SolidMasse moléculaire :495.07STAMBP-IN-1
CAS :<p>STAMBP-IN-1 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release after</p>Formule :C27H28N4O4SDegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :504.62-Aminofluorene
CAS :<p>2-Aminofluorene (2-Fluorenamine) is a biochemical.</p>Formule :C13H11NDegré de pureté :99.9%Couleur et forme :Light Yellow CrystallineMasse moléculaire :181.23ON-013100
CAS :<p>ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.</p>Formule :C19H22O7SDegré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :394.44Pyridostatin
CAS :<p>Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome or</p>Formule :C31H32N8O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :596.64Ribociclib succinate hydrate
CAS :<p>Ribociclib succinate hydrate is a highly specific CDK4/6 inhibitor (IC50s: 10 nM and 39 nM, respectively).</p>Formule :C27H38N8O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :570.65110074-G5
CAS :<p>10074-G5 is an inhibitor of c-Myc-Max dimerization.</p>Formule :C18H12N4O3Degré de pureté :99.51% - 99.67%Couleur et forme :SolidMasse moléculaire :332.31IMM-H007
CAS :<p>IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression</p>Formule :C22H23N5O8Degré de pureté :97.73%Couleur et forme :SolidMasse moléculaire :485.45Phthalazinone pyrazole
CAS :<p>Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.</p>Formule :C18H15N5ODegré de pureté :97.03%Couleur et forme :SolidMasse moléculaire :317.34A-286982
CAS :<p>A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.</p>Formule :C24H27N3O4SDegré de pureté :97.81%Couleur et forme :SolidMasse moléculaire :453.55Adavosertib
CAS :<p>Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.</p>Formule :C27H32N8O2Degré de pureté :98.65% - 99.86%Couleur et forme :SolidMasse moléculaire :500.6PF 477736
CAS :<p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>Formule :C22H25N7O2Degré de pureté :97.58% - 99.94%Couleur et forme :SolidMasse moléculaire :419.48ML216
CAS :<p>ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).</p>Formule :C15H9F4N5OSDegré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :383.32Fadraciclib
CAS :<p>Fadraciclib (CYC065) is an orally available, second-generation ATP-competitive inhibitor of CDK2/CDK9 kinases (IC50s: 5/26 nM).</p>Formule :C21H31N7ODegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :397.52Mitonafide
CAS :<p>Mitonafide (NSC-300288) suppresses the activity of M. tuberculosis NAD+ dependent DNA ligase A. Mitonafide is a DNA intercalating agent.</p>Formule :C16H15N3O4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :313.31CHR-6494 TFA
CAS :<p>CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.</p>Formule :C18H17F3N6O2Degré de pureté :99.50%Couleur et forme :SolidMasse moléculaire :406.36CAN508
CAS :<p>CAN508: potent CDK9/T1 inhibitor; IC50 0.35 μM, Cdk2/E; Ki 13.3 μM, IC50 20 μM; 38x selective; antitumor.</p>Formule :C9H10N6ODegré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :218.22CK7
CAS :<p>CK7, a Cdk2/9 inhibitor, is instrumental in the synthesis of Nek1 inhibitors BSc5231 and BSc5367.</p>Formule :C14H12N6O2SDegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :328.35HMN-214
CAS :<p>HMN-214 (IVX-214) is a potent PLK1 inhibitor with an average IC50 of 0.12 μM.</p>Formule :C22H20N2O5SDegré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :424.47TAK-960
CAS :<p>TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.</p>Formule :C27H34F3N7O3Degré de pureté :97.06%Couleur et forme :SolidMasse moléculaire :561.6Indisulam
CAS :<p>Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.</p>Formule :C14H12ClN3O4S2Degré de pureté :98.68% - 99.77%Couleur et forme :SolidMasse moléculaire :385.85Cyclo(-RGDfK) TFA
CAS :<p>Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).</p>Formule :C29H42F3N9O9Degré de pureté :98.99% - 99.54%Couleur et forme :SolidMasse moléculaire :717.69GSK2850163 hydrochloride
CAS :<p>GSK2850163 hydrochloride is a novel IRE1α inhibitor with IC50 of 20 nM for kinase and 200 nM for RNA enzyme.</p>Formule :C24H30Cl3N3OCouleur et forme :SolidMasse moléculaire :482.87TAK-632
CAS :<p>TAK-632 is a potent pan-Raf inhibitor.</p>Formule :C27H18F4N4O3SDegré de pureté :98% - 99.5%Couleur et forme :SolidMasse moléculaire :554.52SBC-115076
CAS :<p>SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.</p>Formule :C31H33N3O5Degré de pureté :97.07% - 99.89%Couleur et forme :SolidMasse moléculaire :527.617BIO
CAS :<p>7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.</p>Formule :C16H10BrN3O2Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :356.17Apcin-A
CAS :<p>Apcin-A is an anaphase-promoting complex (APC) inhibitor.</p>Formule :C10H14Cl3N5O2Couleur et forme :SolidMasse moléculaire :342.61Roniciclib
CAS :<p>Roniciclib (BAY 1000394) is a potent pan-CDK inhibitor and a novel oral cytotoxic agent. Roniciclib inhibits the activity of cell-cycle CDKs CDK1, CDK2, CDK3, CDK4, and of transcriptional CDKs CDK7 and CDK9 with IC(50) values in the range between 5 and 25 nmol/L.</p>Formule :C18H21F3N4O3SDegré de pureté :98% - 98.63%Couleur et forme :SolidMasse moléculaire :430.44GLPG0187
CAS :<p>GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).</p>Formule :C29H37N7O5SDegré de pureté :99.4% - 99.70%Couleur et forme :SolidMasse moléculaire :595.71Tiazofurin
CAS :<p>Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.</p>Formule :C9H12N2O5SDegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :260.272'-Deoxy-2'-fluorocytidine
CAS :<p>2'-Deoxy-2'-fluorocytidine is an nucleoside analog and inhibits of Crimean-Congo hemorrhagic fever virus (CCHFV) replication potently.</p>Formule :C9H12FN3O4Degré de pureté :99.90%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :245.21Cetraxate hydrochloride
CAS :<p>Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.</p>Formule :C17H24ClNO4Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :341.83PF-06873600
CAS :<p>PF-06873600: oral CDK inhibitor (CDK2/4/6), Ki 0.09-0.16 nM, potential anticancer drug.</p>Formule :C20H27F2N5O4SDegré de pureté :98.77% - 99.55%Couleur et forme :SolidMasse moléculaire :471.52Hu7691
CAS :<p>Hu7691 is an Akt inhibitor that inhibits Akt1, Akt2, and Akt3, suppresses neuroblastoma cell proliferation, and induces differentiation of neuroblastoma cells.</p>Formule :C22H22ClF3N4ODegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :450.88Risdiplam
CAS :<p>Risdiplam (RG7916) is a centrally and peripherally distributed and orally administrable small molecule SMN2 pre-mRNA splicing modifier.Cost-effective and quality-assured.</p>Formule :C22H23N7ODegré de pureté :98.68% - 99.64%Couleur et forme :SolidMasse moléculaire :401.46Palmatine
CAS :<p>Palmatine, also known as Burasaine, inhibits dopamine production and may treat flavivirus, jaundice, dysentery, hypertension, and liver issues.</p>Formule :C21H22NO4Degré de pureté :96.28% - 99.49%Couleur et forme :SolidMasse moléculaire :352.4AT7519 TFA
CAS :<p>AT7519 inhibits CDK1-6 kinases; IC50 ranges 0.018-0.66 μM.</p>Formule :C18H18Cl2F3N5O4Couleur et forme :SolidMasse moléculaire :496.27Poloxin
CAS :<p>Poloxin is a non-ATP competitive Polo-like Kinase 1 inhibitor. It targets the polo-box domain (IC50: appr 4.8 μM).</p>Formule :C18H19NO3Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :297.35Palbociclib dihydrochloride
<p>Palbociclib, oral CDK4/6 inhibitor (IC50: 11/16 nM), targets HR+/HER2- breast cancer and hepatocellular carcinoma.</p>Formule :C24H31Cl2N7O2Couleur et forme :SolidMasse moléculaire :520.45SPHINX
CAS :<p>SPHINX is a new generation inhibitor of SPRK1</p>Formule :C17H17F3N2O3Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :354.32Cdk5 Substrate acetate
<p>Cdk5, a serine/threonine kinase active in neurons, phosphorylates proteins like histone H1; its synthetic substrate has a Km of 5 µM.</p>Formule :C55H103N15O14Degré de pureté :96.21%Couleur et forme :SolidMasse moléculaire :1198.5AZD-5438
CAS :<p>AZD-5438 is an effective inhibitor of CDK, for CDK1(IC50=16 nM), CDK2(IC50=6 nM), CDK9(IC50=20 nM).</p>Formule :C18H21N5O2SDegré de pureté :99.73% - 99.87%Couleur et forme :SolidMasse moléculaire :371.46
