
Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(116 produits)
- CDK(547 produits)
- Arrêt du cycle cellulaire(5 produits)
- Chk(48 produits)
- DYRK(46 produits)
- Dynamine(27 produits)
- Ferroptose(233 produits)
- HSP(180 produits)
- Intégrine(276 produits)
- Kinésine(87 produits)
- LIM Kinase(21 produits)
- Microtubules associés(273 produits)
- PKC(128 produits)
- PLK(25 produits)
- ROCK(61 produits)
- Rho(6 produits)
- Wee1(14 produits)
- c-Myc(77 produits)
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3935 produits trouvés pour "Cycle cellulaire/point de contrôle"
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Levomefolate calcium
CAS :Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.Formule :C20H23CaN7O6Degré de pureté :97.35%Couleur et forme :Off-White To Pale Yellow SolidMasse moléculaire :497.525'-Deoxy-5-fluorocytidine
CAS :5'-Deoxy-5-fluorocytidine is an intermediate metabolite of the DNA synthesis inhibitor capecitabine.Formule :C9H12FN3O4Degré de pureté :99.67%Couleur et forme :White SolidMasse moléculaire :245.21LY3177833
CAS :LY3177833 is an Cdc7 kinase inhibitor (IC50 : 3.3 nM)Formule :C16H12FN5ODegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :309.3Ref: TM-T7810
1mg38,00€5mg80,00€1mL*10mM (DMSO)87,00€10mg109,00€25mg212,00€50mg318,00€100mg477,00€200mg677,00€AZD-7762
CAS :AZD-7762, an effective and specific inhibitor of Chk1(IC50=5 nM), is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.Formule :C17H19FN4O2SDegré de pureté :98.96% - 99.19%Couleur et forme :SolidMasse moléculaire :362.42Ref: TM-T6093
1mg35,00€2mg50,00€5mg77,00€1mL*10mM (DMSO)84,00€10mg90,00€25mg167,00€50mg265,00€100mg424,00€Fosifloxuridine nafalbenamide
CAS :Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.
Formule :C29H29FN3O9PDegré de pureté :95.87%Couleur et forme :SolidMasse moléculaire :613.53Barasertib-HQPA
CAS :Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.
Formule :C26H30FN7O3Degré de pureté :98.43% - 99.29%Couleur et forme :SolidMasse moléculaire :507.56N6,N6-Dimethyladenosine
CAS :N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.Formule :C12H17N5O4Degré de pureté :98.79%Couleur et forme :White PowderMasse moléculaire :295.29CBFβ Inhibitor
CAS :CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.Formule :C12H14N2OSDegré de pureté :96.50%Couleur et forme :SolidMasse moléculaire :234.32CW-069
CAS :CW-069 (IC50=75 μM), an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.Formule :C23H21IN2O3Degré de pureté :97.52% - 99.52%Couleur et forme :SolidMasse moléculaire :500.33Ref: TM-T6209
1mg40,00€5mg86,00€1mL*10mM (DMSO)94,00€10mg118,00€25mg205,00€50mg290,00€100mg409,00€500mg888,00€NITD-2
CAS :NITD-2 is a DENV RdRp inhibitor with poor cell membrane penetration; no vaccine or antiviral for DENV exists.Formule :C23H19N3O4SDegré de pureté :98.03% - 99.46%Couleur et forme :SolidMasse moléculaire :433.48Ref: TM-T8886
1mg74,00€5mg170,00€1mL*10mM (DMSO)188,00€10mg274,00€25mg472,00€50mg655,00€100mg944,00€200mg1.264,00€Indirubin-3′-oxime
CAS :Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.Formule :C16H11N3O2Degré de pureté :98.34%Couleur et forme :SolidMasse moléculaire :277.28Ref: TM-T9138
1mg44,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg120,00€25mg236,00€50mg356,00€100mg532,00€200mg772,00€Proguanil
CAS :Proguanil (Chloroguanide) is a prophylactic antimalarial drug that acts primarily through its active metabolite, Cycloguanil, which inhibits the DHFR enzyme .Formule :C11H16ClN5Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :253.73Cyclo(-RGDfK)
CAS :Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.Formule :C27H41N9O7Degré de pureté :95.29% - >99.99%Couleur et forme :SolidMasse moléculaire :603.67GNF2133 hydrochloride
CAS :GNF2133 hydrochloride: selective oral DYRK1A inhibitor (IC50: 0.0062 μM), boosts β-cell growth and insulin, potential for type 1 diabetes research.Formule :C24H31ClN6O2Couleur et forme :SolidMasse moléculaire :471.0CID44216842
CAS :CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.Formule :C22H20BrN3O3SDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :486.38Ref: TM-T8930
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg85,00€25mg159,00€50mg244,00€100mg359,00€200mg512,00€N-Cyclohexyl-4-[1-(1-piperazinyl)-2,6-naphthyridin-3-yl]-2-pyridinamine
CAS :Novel 2,6-naphthyridine inhibits PKC/PKD, identified by HTS.Formule :C23H28N6Degré de pureté :98.35%Couleur et forme :SolidMasse moléculaire :388.51Thiazovivin
CAS :Thiazovivin, a ROCK inhibitor (IC50: 0.5 μM), increases the survival rate of hESC.Formule :C15H13N5OSDegré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :311.36Ref: TM-T2155
1mg34,00€2mg46,00€5mg64,00€1mL*10mM (DMSO)70,00€10mg98,00€25mg180,00€50mg304,00€100mg444,00€VLX1570
CAS :VLX1570 is a competitive inhibitor of proteasome DUB activity with IC50 ranging from 4.2 uM to 8.6 uM. It has potent inhibition for USP14.Formule :C23H17F2N3O6Degré de pureté :98.53% - 99.91%Couleur et forme :SolidMasse moléculaire :469.39Ref: TM-T4067
1mg90,00€2mg146,00€5mg245,00€1mL*10mM (DMSO)251,00€10mg385,00€25mg645,00€50mg888,00€100mg1.234,00€Ibezapolstat
CAS :Ibezapolstat (ACX-362E) is an antibiotic with antibacterial activity that inhibits Clostridium difficile.Formule :C18H20Cl2N6O2Degré de pureté :98% - 99.429%Couleur et forme :SolidMasse moléculaire :423.3Ref: TM-T10243
1mg54,00€5mg114,00€1mL*10mM (DMSO)127,00€10mg185,00€25mg369,00€50mg594,00€100mg952,00€CCG-100602
CAS :CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).Formule :C21H17ClF6N2O2Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :478.82Ref: TM-T22062
5mg35,00€1mL*10mM (DMSO)40,00€10mg54,00€25mg108,00€50mg178,00€100mg286,00€200mg425,00€Adavosertib
CAS :Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.Formule :C27H32N8O2Degré de pureté :98.65% - 99.86%Couleur et forme :SolidMasse moléculaire :500.6Ref: TM-T2077
5mg46,00€1mL*10mM (DMSO)49,00€10mg66,00€25mg81,00€50mg96,00€100mg110,00€200mg161,00€500mg260,00€Y16
CAS :Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG with a Kd of 76 nM.Cost-effective and quality-assured.Formule :C24H20N2O3Degré de pureté :98.26% - 99.85%Couleur et forme :SolidMasse moléculaire :384.43Ref: TM-T3553
1mg34,00€2mg48,00€5mg70,00€1mL*10mM (DMSO)77,00€10mg109,00€25mg177,00€50mg263,00€100mg389,00€Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base)
Gly-Arg-Gly-Asp-Ser (GRGDS) acetate is a cell binding protein domain derived from the cell-binding region of fibronectin.Formule :C19H34N8O11Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :550.52Cucurbitacin B
CAS :Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Formule :C32H46O8Degré de pureté :97.1% - 99.93%Couleur et forme :SolidMasse moléculaire :558.70GRGDSP acetate(91037-75-1 free base)
GRGDSP acetate(91037-75-1 free base) is a synthetic linear RGD peptide and is an integrin inhibitor.Formule :C24H41N9O12Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :647.64BMS-5
CAS :BMS-5 (LIMKi 3) is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively.Formule :C17H14Cl2F2N4OSDegré de pureté :98.01% - 99.88%Couleur et forme :SolidMasse moléculaire :431.29Ref: TM-T4598
1mg40,00€2mg52,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg116,00€25mg188,00€50mg281,00€100mg420,00€2′-Deoxy-2′-fluoroguanosine
CAS :2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM).Formule :C10H12FN5O4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :285.232-Aminofluorene
CAS :2-Aminofluorene (2-Fluorenamine) is a biochemical.Formule :C13H11NDegré de pureté :99.9%Couleur et forme :Light Yellow CrystallineMasse moléculaire :181.23CCT245737
CAS :CCT245737 is an orally active, selective Chk1 inhibitor, and is >1,000-fold selective over CHK2 and CDK1.Cost-effective and quality-assured.Formule :C16H16F3N7ODegré de pureté :98.28% - 99.93%Couleur et forme :SolidMasse moléculaire :379.34Ref: TM-T7080
1mg37,00€2mg49,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg113,00€25mg213,00€50mg350,00€100mg523,00€Monastrol
CAS :Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Formule :C14H16N2O3SDegré de pureté :98.02% - 98.59%Couleur et forme :SolidMasse moléculaire :292.35Ref: TM-T4048
1mg46,00€5mg73,00€10mg92,00€1mL*10mM (DMSO)93,00€25mg178,00€50mg295,00€100mg477,00€500mg1.018,00€CK7
CAS :CK7, a Cdk2/9 inhibitor, is instrumental in the synthesis of Nek1 inhibitors BSc5231 and BSc5367.Formule :C14H12N6O2SDegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :328.35Ref: TM-T9615
1mg50,00€5mg114,00€1mL*10mM (DMSO)126,00€10mg177,00€25mg356,00€50mg557,00€100mg858,00€200mg1.153,00€THAL-SNS-032
CAS :THAL-SNS-032 is a selective CDK9 degrader PROTAC.Formule :C40H52N8O10S2Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :869.02Ref: TM-T17069
1mg110,00€5mg259,00€10mg389,00€1mL*10mM (DMSO)389,00€25mg622,00€50mg884,00€100mg1.198,00€DUB-IN-3
CAS :DUB-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor and the IC50 for USP8 is 0.56 μM.Formule :C16H9N5ODegré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :287.28Ref: TM-T11112
1mg130,00€2mg178,00€5mg309,00€1mL*10mM (DMSO)324,00€10mg442,00€25mg705,00€50mg982,00€100mg1.333,00€500mg2.655,00€AUZ 454
CAS :AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50/18.6/15.4/9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.Formule :C24H26F3N7O2Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :501.5P 22077
CAS :P 22077 (P22077) is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM. It also inhibits the closely related USP47.Formule :C12H7F2NO3S2Degré de pureté :97.9% - 99.64%Couleur et forme :SolidMasse moléculaire :315.32LDC-4297 HCl (1453834-21-3(free base))
LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.
Formule :C23H29ClN8ODegré de pureté :100%Couleur et forme :SolidMasse moléculaire :469.026-AZATHYMINE
CAS :6-azathymine inhibits D-3-aminoisobutyrate-pyruvate aminotransferase; 6-azauracil competes with beta-alanine, uncompetitive with pyruvic acid, Ki ~8.9 mM.Formule :C4H5N3O2Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :127.1TR-14035
CAS :TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).Formule :C24H21Cl2NO5Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :474.33Ref: TM-T5310
1mg50,00€5mg99,00€1mL*10mM (DMSO)102,00€10mg152,00€25mg245,00€50mg353,00€100mg492,00€200mg700,00€CX-5461
CAS :CX5461 is an orally rRNA synthesis inhibitor that inhibits Pol I-driven rRNA transcription. CX5461 has antitumor activity. Cost-effective and quality-assured.Formule :C27H27N7O2SDegré de pureté :95.44% - 99.4%Couleur et forme :SolidMasse moléculaire :513.61Indisulam
CAS :Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.Formule :C14H12ClN3O4S2Degré de pureté :98.68% - 99.77%Couleur et forme :SolidMasse moléculaire :385.85Ref: TM-T4321
1mg34,00€2mg43,00€5mg63,00€1mL*10mM (DMSO)69,00€10mg88,00€25mg130,00€50mg198,00€100mg298,00€RKI-1447
CAS :RKI-1447 is a potent inhibitor of ROCK1 and ROCK2. It has anti-invasive and antitumor activities.Formule :C16H14N4O2SDegré de pureté :98% - 99.73%Couleur et forme :SolidMasse moléculaire :326.37Ref: TM-T1898
5mg49,00€1mL*10mM (DMSO)54,00€10mg93,00€25mg177,00€50mg295,00€100mg391,00€200mg494,00€500mg797,00€Risdiplam
CAS :Risdiplam (RG7916) is a centrally and peripherally distributed and orally administrable small molecule SMN2 pre-mRNA splicing modifier.Cost-effective and quality-assured.Formule :C22H23N7ODegré de pureté :98.68% - 99.64%Couleur et forme :SolidMasse moléculaire :401.46BVDV-IN-1
CAS :BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM.Formule :C20H22N4ODegré de pureté :98.43%Couleur et forme :SolidMasse moléculaire :334.41Ref: TM-T9103
1mg38,00€5mg86,00€1mL*10mM (DMSO)95,00€10mg124,00€25mg241,00€50mg355,00€100mg507,00€200mg687,00€NVP-LCQ195
CAS :NVP-LCQ195 (LCQ-195) (AT9311) is a potent inhibitor of CDK1, CDK2, CDK3 and CDK5 (IC50: 1-42 nM).Formule :C17H19Cl2N5O4SDegré de pureté :99.56% - 99.85%Couleur et forme :SolidMasse moléculaire :460.33Ref: TM-TQ0068
1mg46,00€5mg92,00€1mL*10mM (DMSO)94,00€10mg138,00€25mg255,00€50mg374,00€100mg533,00€200mg705,00€Deoxythymidine triphosphate
CAS :Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.Formule :C10H17N2O14P3·XNaDegré de pureté :99.78%Couleur et forme :White Amorphous PowderMasse moléculaire :482.17(free base)Ro3280
CAS :Ro3280 (Ro5203280) is an effective, specific inhibitor of PLK1(IC50=3, Kd=0.09 nM).Formule :C27H35F2N7O3Degré de pureté :97.1% - >99.99%Couleur et forme :SolidMasse moléculaire :543.61Ilorasertib
CAS :Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Formule :C25H21FN6O2SDegré de pureté :96.17% - 97.49%Couleur et forme :SolidMasse moléculaire :488.54Dalpiciclib hydrochloride
Dalpiciclib (SHR-6390) HCl is an oral CDK4/6 inhibitor with IC50s of 12.4/9.9 nM, an antitumor for breast and esophageal cancers.Formule :C25H31ClN6O2Couleur et forme :SolidMasse moléculaire :483.01MLN8054
CAS :MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.Formule :C25H15ClF2N4O2Degré de pureté :98.07% - 98.26%Couleur et forme :SolidMasse moléculaire :476.86Ref: TM-T6315
1mg50,00€2mg67,00€5mg84,00€1mL*10mM (DMSO)88,00€10mg120,00€25mg220,00€50mg356,00€100mg537,00€TCID
CAS :TCID (UCH-L3 Inhibitor)(IC50=0.6 μM) is a DUB inhibitor of ubiquitin C-terminal hydrolase L3. It has the 125-fold selectivity to L1.Formule :C9H2Cl4O2Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :283.92PND-1186
CAS :PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).Formule :C25H26F3N5O3Degré de pureté :99.14% - 99.75%Couleur et forme :SolidMasse moléculaire :501.5SNS-314
CAS :SNS-314 inhibits Aurora kinases A and B, blocking cell division in AK-overexpressing tumors.Formule :C18H15ClN6OS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.93Aurora kinase inhibitor-3
CAS :Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK,Formule :C21H18F3N5ODegré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :413.4Ref: TM-T5524
1mg66,00€2mg89,00€5mg152,00€1mL*10mM (DMSO)167,00€10mg236,00€25mg401,00€50mg580,00€100mg797,00€200mg1.099,00€STAMBP-IN-1
CAS :STAMBP-IN-1 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release afterFormule :C27H28N4O4SDegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :504.6Ref: TM-T8706
1mg67,00€5mg152,00€1mL*10mM (DMSO)192,00€10mg236,00€25mg507,00€50mg730,00€100mg1.018,00€Abemaciclib
CAS :Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity.Formule :C27H32F2N8Degré de pureté :99.43% - 99.87%Couleur et forme :SolidMasse moléculaire :506.59GSK2850163 hydrochloride
CAS :GSK2850163 hydrochloride is a novel IRE1α inhibitor with IC50 of 20 nM for kinase and 200 nM for RNA enzyme.Formule :C24H30Cl3N3OCouleur et forme :SolidMasse moléculaire :482.87RNase L-IN-2
CAS :RNase L-IN-2 activates RNase L at 22 uM, has antiviral effects on various RNA viruses, non-toxic at effective levels.Formule :C16H14N2O2SDegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :298.36Ref: TM-T8591
1mg120,00€1mL*10mM (DMSO)243,00€5mg264,00€10mg395,00€25mg627,00€50mg890,00€100mg1.198,00€200mg1.603,00€THZ1
CAS :THZ1 (CDK7 inhibitor) is a selective inhibitor of CDK7, binding to the Cys residue located at the outer end of the classical kinase domain. Cost-effective and quality-assured.Formule :C31H28ClN7O2Degré de pureté :97.42% - 99.27%Couleur et forme :SolidMasse moléculaire :566.05NY2267
CAS :NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethylFormule :C38H43N3O6Degré de pureté :99.16% - 99.27%Couleur et forme :SolidMasse moléculaire :637.76A-205804
CAS :A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.Formule :C15H12N2OS2Degré de pureté :98.07% - 98.52%Couleur et forme :SolidMasse moléculaire :300.4Ref: TM-T2254
2mg42,00€5mg50,00€1mL*10mM (DMSO)67,00€10mg77,00€25mg152,00€50mg258,00€100mg505,00€500mg1.108,00€TH5427 hydrochloride
CAS :TH5427 HCl inhibits NUDT5 with 29 nM IC50; 690x more selective over MTH1; blocks ATP in breast cancer cells, hindering growth.Formule :C20H21Cl3N8O3Couleur et forme :SolidMasse moléculaire :527.79OSU-T315
CAS :OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.Formule :C30H30F3N5ODegré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :533.59Ref: TM-T5485
1mg88,00€5mg187,00€1mL*10mM (DMSO)220,00€10mg298,00€25mg533,00€50mg755,00€100mg1.008,00€200mg1.359,00€HAMNO
CAS :HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).Formule :C17H13NO2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :263.29IMT1B
CAS :IMT1B (LDC203974) is an oral POLRMT inhibitor that curbs mtDNA expression and has anti-cancer properties.Formule :C24H21ClFNO6Degré de pureté :98.26% - 99.83%Couleur et forme :SolidMasse moléculaire :473.88Ref: TM-T8842
1mg138,00€5mg295,00€1mL*10mM (DMSO)309,00€10mg505,00€25mg733,00€50mg888,00€100mg1.251,00€AS2863619
CAS :AS2863619 is an oral inhibitor of cyclin-dependent kinase(CDK8) and CDK19. Inhibition of CDK8/19 enhances STAT5 activation.Cost-effective and quality-assured.Formule :C16H14Cl2N8ODegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :405.24Ref: TM-T8378
1mg124,00€2mg170,00€5mg260,00€1mL*10mM (DMSO)286,00€10mg409,00€25mg677,00€50mg954,00€100mg1.288,00€Y16 acetate(429653-73-6 free base)
Y16 acetate(429653-73-6 free base) is a G-protein–coupled Rho GEFs inhibitor; works synergistically with Rhosin/G04 in inhibiting LARG-RhoA interaction, RhoAFormule :C51H74N14O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1091.24BRD9876
CAS :BRD9876 is a selective inhibitor of MM1S growth.Formule :C16H14N2Degré de pureté :97.81%Couleur et forme :SolidMasse moléculaire :234.33-Methylcytidine
CAS :3-Methylcytidine as biomarkers of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.Formule :C10H15N3O5Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :257.24NSC23005 Sodium
CAS :NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.Formule :C13H16NNaO4SDegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :305.32HMN-176
CAS :HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1).Formule :C20H18N2O4SDegré de pureté :98.92% - 98.99%Couleur et forme :SolidMasse moléculaire :382.43Ref: TM-T3643
1mg40,00€2mg52,00€1mL*10mM (DMSO)74,00€5mg84,00€10mg113,00€25mg178,00€50mg333,00€100mg495,00€500mg1.071,00€Pritelivir
CAS :Pritelivir (BAY 57-1293) (BAY 57-1293) is a potent helicase-primase inhibitor with active against HSV-1 and HSV-2 (IC50: 20 nM).Formule :C18H18N4O3S2Degré de pureté :97.96% - 99.42%Couleur et forme :SolidMasse moléculaire :402.49AI-10-49
CAS :AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.Formule :C30H22F6N6O5Degré de pureté :97.14%Couleur et forme :SolidMasse moléculaire :660.52Ref: TM-T6753
2mg38,00€5mg57,00€1mL*10mM (DMSO)84,00€10mg92,00€25mg160,00€50mg231,00€100mg343,00€200mg485,00€Senexin A
CAS :Senexin A is an effective and selective CDK8 inhibitor that also inhibits CDK19 with Kd values of 0.83 microns and 0.31 microns, respectively.Formule :C17H14N4Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :274.32Ref: TM-T5673
1mg34,00€1mL*10mM (DMSO)71,00€5mg73,00€10mg94,00€25mg177,00€50mg323,00€100mg460,00€200mg622,00€RK33
CAS :"RK33 is a DDX3 inhibitor causing G1 arrest, apoptosis, and radiation sensitization in DDX3-overexpressing cells."Formule :C23H20N6O3Degré de pureté :99.04% - 99.72%Couleur et forme :SolidMasse moléculaire :428.44LY2334737
CAS :LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.Formule :C17H25F2N3O5Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :389.39Ref: TM-T4061
1mg35,00€5mg79,00€1mL*10mM (DMSO)94,00€10mg111,00€25mg215,00€50mg319,00€100mg442,00€200mg583,00€T-5224
CAS :T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcriptionFormule :C29H27NO8Degré de pureté :97.88% - 99.29%Couleur et forme :SolidMasse moléculaire :517.53Ref: TM-T5416
1mg48,00€5mg96,00€1mL*10mM (DMSO)107,00€10mg144,00€25mg254,00€50mg424,00€100mg627,00€200mg998,00€BS-181 hydrochloride
CAS :BS-181 hydrochloride (BS-181 HCl) is a highly selective CDK7 inhibitor with IC50 of 21 nM.Formule :C22H32N6·HClDegré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :416.99Ref: TM-T6162
200mgÀ demander1mg37,00€2mg52,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg116,00€25mg250,00€50mg416,00€100mg645,00€HMN-214
CAS :HMN-214 (IVX-214) is a potent PLK1 inhibitor with an average IC50 of 0.12 μM.Formule :C22H20N2O5SDegré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :424.47Ref: TM-T2438
1mg38,00€2mg50,00€5mg80,00€1mL*10mM (DMSO)87,00€10mg117,00€25mg207,00€50mg333,00€100mg477,00€500mg1.063,00€TAK-960
CAS :TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.Formule :C27H34F3N7O3Degré de pureté :97.06%Couleur et forme :SolidMasse moléculaire :561.6Ref: TM-T7200
1mg60,00€2mg85,00€5mg114,00€10mg161,00€1mL*10mM (DMSO)161,00€25mg279,00€50mg464,00€100mg672,00€ZCL278
CAS :ZCL278 is a selective Cdc42 GTPase inhibitor.Formule :C21H19BrClN5O4S2Degré de pureté :96.29% - 99.72%Couleur et forme :SolidMasse moléculaire :584.89Ref: TM-T1855
5mg52,00€10mg74,00€1mL*10mM (DMSO)74,00€25mg129,00€50mg210,00€100mg294,00€200mg470,00€500mg763,00€Cyclo(-RGDfK) TFA
CAS :Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).Formule :C29H42F3N9O9Degré de pureté :98.99% - 99.54%Couleur et forme :SolidMasse moléculaire :717.69Triazavirin
CAS :Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.Formule :C5H7N6NaO5SDegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :286.2Netarsudil free base
CAS :Netarsudil (AR-11324), a ROCK inhibitor, treats glaucoma by increasing eye outflow and lowering IOP, with mild hyperemia as a side effect.Formule :C28H27N3O3Couleur et forme :SolidMasse moléculaire :453.53Pyridostatin TFA
CAS :Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-Formule :C37H35F9N8O11Degré de pureté :97.09% - 99.84%Couleur et forme :SolidMasse moléculaire :938.71Hydroxyfasudil
CAS :Hydroxyfasudil (Hydroxy-Fasudil) is a ROCK inhibitor(IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively).Formule :C14H17N3O3SDegré de pureté :98.13%Couleur et forme :SolidMasse moléculaire :307.37HQ461
CAS :HQ461, a molecular glue, boosts CDK12-DDB1 binding, lowers cyclin K, impedes CDK12 phosphorylation, hinders DNA repair genes, and induces cell death.Formule :C15H15N5OS2Degré de pureté :98.11%Couleur et forme :SolidMasse moléculaire :345.44Ref: TM-T9849
1mg43,00€2mg56,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg144,00€25mg319,00€50mg537,00€100mg767,00€500mg1.558,00€AG-636
CAS :AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.Formule :C21H17N3O2Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :343.38TAK-960 hydrochloride
CAS :TAK-960 hydrochloride is an oral, potent PLK1 inhibitor with IC50 of 0.8 nM, effective against various tumor cells and xenografts.Formule :C27H35ClF3N7O3Couleur et forme :SolidMasse moléculaire :598.06BUR1
CAS :BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.Formule :C16H17N5Degré de pureté :90%Couleur et forme :SolidMasse moléculaire :279.34BMH-21
CAS :BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.Formule :C21H20N4O2Degré de pureté :99.47% - 99.84%Couleur et forme :SolidMasse moléculaire :360.41P18IN011
CAS :P18IN011 (P18IN011 - CAS 77408-67-4 - Calbiochem) is a novel inhibitor of p18(INK4C).
Formule :C15H12N2O5SDegré de pureté :97.63%Couleur et forme :SolidMasse moléculaire :332.33DUB-IN-2
CAS :Dub-in-2, with an IC50 value of 0.28 for USP8, is an effective deubiquitinase inhibitor.Formule :C15H9N5ODegré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :275.26Ref: TM-T11111
1mg54,00€5mg155,00€1mL*10mM (DMSO)169,00€10mg233,00€25mg467,00€50mg682,00€100mg990,00€TH588 hydrochloride
CAS :TH588 hydrochloride is first-in-class inhibitor of nudix hydrolase family that selectively and effectively bind and inhibit the MTH1 with IC50 value of 5 nM.Formule :C13H13Cl3N4Couleur et forme :SolidMasse moléculaire :331.63Hydroxyfasudil Hydrochloride
CAS :Hydroxyfasudil Hydrochloride (HA 1100 hydrochloride) is a ROCK1/2 inhibitor (IC50s: 0.73/0.72 μM).Formule :C14H18ClN3O3SDegré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :343.83α2β1 Integrin Ligand Peptide acetate
α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) is a potential antagonist of α2β1 integrin receptor.Formule :C16H26N4O11Degré de pureté :98.46%Couleur et forme :SolidMasse moléculaire :450.4DUB-IN-1
CAS :DUB-IN-1, with an IC50 value of 0.24 for USP8, is an active inhibitor of ubiquitin-specific protease (USPs).Formule :C20H11N5ODegré de pureté :98.33% - 98.96%Couleur et forme :SolidMasse moléculaire :337.33Ref: TM-T11110
1mg62,00€5mg110,00€1mL*10mM (DMSO)122,00€10mg173,00€25mg334,00€50mg469,00€100mg618,00€200mg848,00€PHA-680632
CAS :PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.Formule :C28H35N7O2Degré de pureté :98.2%Couleur et forme :SolidMasse moléculaire :501.62Purvalanol B
CAS :Purvalanol B (NG 95) is a CDK inhibitor that inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively)Formule :C20H25ClN6O3Degré de pureté :98.95%Couleur et forme :SolidMasse moléculaire :432.9Ref: TM-T7167
1mg34,00€2mg46,00€5mg67,00€1mL*10mM (DMSO)75,00€10mg90,00€25mg130,00€50mg203,00€100mg305,00€200mg447,00€FOY 251
CAS :FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.Formule :C17H19N3O7SDegré de pureté :97.11% - 99.33%Couleur et forme :SolidMasse moléculaire :409.41Ref: TM-T8676
1mg51,00€5mg110,00€1mL*10mM (DMSO)126,00€10mg177,00€25mg300,00€50mg424,00€100mg605,00€500mg1.198,00€Trimethoprim sulfate
CAS :Trimethoprim sulfate, a dihydrofolate reductase inhibitor, treats bacterial infections and sometimes malaria; may depress hematopoiesis.Formule :C28H38N8O10SCouleur et forme :SolidMasse moléculaire :678.72

