
Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(94 produits)
- CDK(500 produits)
- Arrêt du cycle cellulaire(4 produits)
- Chk(42 produits)
- DYRK(48 produits)
- Dynamine(23 produits)
- Ferroptose(215 produits)
- HSP(169 produits)
- Intégrine(224 produits)
- Kinésine(66 produits)
- LIM Kinase(19 produits)
- Microtubules associés(261 produits)
- PKC(102 produits)
- PLK(28 produits)
- ROCK(70 produits)
- Rho(2 produits)
- Wee1(15 produits)
- c-Myc(69 produits)
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3477 produits trouvés pour "Cycle cellulaire/point de contrôle"
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PF-2771
CAS :<p>PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.</p>Formule :C29H36ClN5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :554.08DNA Gyrase-IN-5
CAS :<p>DNA Gyrase-IN-5 is a potent inhibitor of DNA gyrase (IC50: 0.10 μM) and has an antibacterial effect on both wild-type and drug-resistant strains.</p>Formule :C25H15BrClN5Couleur et forme :SolidMasse moléculaire :500.78Syntelin
CAS :<p>Syntelin: a selective CENP-E inhibitor with an IC50 of 160 nM; distinct from GSK923295, effective on resistant mutants.</p>Formule :C21H20N6O2S3Couleur et forme :SolidMasse moléculaire :484.62Zalunfiban
CAS :<p>RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.</p>Formule :C16H18N8O2SCouleur et forme :SolidMasse moléculaire :386.43MDK6204
CAS :<p>MDK6204 is a selective inhibitor of CLK1 and CLK2.</p>Formule :C20H20N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :360.41Cylindrospermopsin
CAS :<p>Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.</p>Formule :C15H21N5O7SCouleur et forme :SolidMasse moléculaire :415.42Cdc7-IN-4
CAS :<p>Cdc7-IN-4 is a potent inhibitor of Cdc7 kinase.</p>Formule :C22H24F3N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :479.45Valategrast
CAS :<p>Valategrast: potent, oral dual α4β1/α4β7 integrin antagonist, may treat COPD and asthma.</p>Formule :C30H32Cl3N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :604.95Cyclapolin 9
CAS :<p>Cyclapolin 9: Selective PLK1 inhibitor, IC50 500 nM, ATP-competitive, inactive against other kinases.</p>Formule :C9H4F3N3O4SDegré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :307.21Binucleine 2
CAS :<p>Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.</p>Formule :C13H11ClFN5Couleur et forme :SolidMasse moléculaire :291.71IRE1α kinase-IN-7
CAS :<p>IRE1α kinase-IN-7 is a chemical compound functioning as an inhibitor of IRE1α kinase, primarily utilized in the research of diseases related to endoplasmic</p>Formule :C28H25F3N6OCouleur et forme :SolidMasse moléculaire :518.531-Methylcytosine
CAS :<p>1-Methylcytosine (4-amino-1-methylpyrimidin-2(1H)-one) is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired with</p>Formule :C5H7N3ODegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :125.13ANI-7
CAS :<p>ANI-7, an AhR pathway activator, selectively impedes MCF-7 breast cancer cell growth (GI50: 0.56 μM).</p>Formule :C13H8Cl2N2Degré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :263.12WF-536 Hydrochloride
CAS :<p>WF-536 Hydrochloride, a novel inhibitor of ROCK, inhibits tumour metastasis in some animal models.</p>Formule :C14H16ClN3OCouleur et forme :SolidMasse moléculaire :277.75BA-1049
CAS :<p>BA-1049 is a selective ROCK2 inhibitor.</p>Formule :C16H21N3O2SCouleur et forme :SolidMasse moléculaire :319.42M443
CAS :<p>M443 is a potent small molecule inhibitor of MRK that inhibits radiation-induced activation of p38 and Chk2 and can be used in cancer research.</p>Formule :C31H30F3N7O2Degré de pureté :98.95%Couleur et forme :SolidMasse moléculaire :589.61XIE18-6
CAS :<p>XIE18-6 is a novel INK4C inhibitor that blocks p18 activity and promotes ex vivo expansion of human and murine hematopoietic stem cells.</p>Formule :C18H15NO6SDegré de pureté :99.712%Couleur et forme :SolidMasse moléculaire :373.38CI-898 HCl
CAS :<p>CI-898 HCl: lipophilic antifolate, DHFR inhibitor, effective on methotrexate-resistant cancers, synergizes with other drugs in advanced P338 leukemia.</p>Formule :C19H26Cl3N5O3Couleur et forme :SolidMasse moléculaire :478.8CDK4/6-IN-14
CAS :<p>CDK4/6-IN-14: potent CDK4/6 inhibitor, IC50s 10/16 nM, >60-fold selectivity over CDKs 1/2/7/9, selective across 205 kinases.</p>Formule :C24H27ClFN7OCouleur et forme :SolidMasse moléculaire :483.97IRE1α kinase-IN-9
CAS :<p>IRE1α kinase-IN-9 (compound 2) is a potent inhibitor of IRE-1α, demonstrating an average IC50 value of less than 0.1 μM.</p>Formule :C24H24N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.46Trimetrexate glucuronate
CAS :<p>Trimetrexate glucuronate, a folic acid foe, blocks DNA/RNA synthesis by inhibiting purine and thymidylic acid production, may fight tumors.</p>Formule :C25H33N5O10Couleur et forme :SolidMasse moléculaire :563.564TCS 2314
CAS :<p>TCS 2314 is an orally active and selective very late antigen-4 antagonist (IC50: 4.4 nM).</p>Formule :C28H34N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :522.59Thiarabine
CAS :<p>Thiarabine displays effective anti-tumor activity. It also inhibition of DNA synthesis.</p>Formule :C9H13N3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :259.28ROCK-IN-4
CAS :<p>ROCK-IN-4: Inhibits ROCK, sustains NO release, disrupts F-actin, hinders HTM cell respiration, aids glaucoma research.</p>Formule :C20H26ClFN4O7SCouleur et forme :SolidMasse moléculaire :520.96USP28-IN-2
CAS :<p>USP28-IN-2 selectively inhibits USP28 (IC50=0.3 μM), degrades c-Myc, kills cancer cells, lowers ankyrin-1/2, and enhances Regorafenib effects.</p>Formule :C23H20Cl2N2O3SCouleur et forme :SolidMasse moléculaire :475.39IRE1α kinase-IN-8
CAS :<p>IRE1α kinase-IN-8, a benzoheterocyclecarboxaldehyde derivative, serves as a potent inhibitor of IRE-1α.</p>Formule :C23H22N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :406.43Dihydro-5-azacytidine acetate
CAS :<p>Dihydro-5-azacytidine acetate (DHAC), a nucleoside analog, becomes integrated into DNA, thereby inhibiting DNA methylation, and exhibits antitumor activity [1</p>Formule :C10H18N4O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :306.27Cdc7-IN-5
CAS :<p>Cdc7-IN-5: potent Cdc7 serine-threonine kinase inhibitor, critical for starting DNA replication.</p>Formule :C25H23N3O5Degré de pureté :97.15%Couleur et forme :SolidMasse moléculaire :445.47JH-XIV-68-3
CAS :<p>JH-XIV-68-3: Selective DYRK1A/B inhibitor; effective in HNSCC cell lines.</p>Formule :C21H17F3N8OCouleur et forme :SolidMasse moléculaire :454.41CM03
CAS :<p>CM03 is a cell-selective G-quadruplex ligand with anti-cancer activity, stabilizing G4 genes, useful in pancreatic cancer research.</p>Formule :C34H44N6O6Degré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :632.75Akt1&PKA-IN-2
CAS :<p>Akt1&PKA-IN-2 ((R)-29) inhibits AKT1, PKAα, CDK2 with IC50s: 0.007, 0.01, 0.69 µM respectively.</p>Formule :C20H17Cl2N3OCouleur et forme :SolidMasse moléculaire :386.27CDK1-IN-1
CAS :<p>CDK1-IN-7 inhibits CDK1 at 161.2 nM, triggers p53-dependent apoptosis, and selectively targets tumor growth.</p>Formule :C27H23N5O3Couleur et forme :SolidMasse moléculaire :465.5Werner syndrome RecQ helicase-IN-4
CAS :<p>Werner syndrome RecQ helicase-IN-4 is a WRN inhibitor with anticancer and anti-proliferative activity, used in colorectal and gastric cancer research.</p>Formule :C32H33F3N8O5Degré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :666.65FLDP-5
CAS :<p>FLDP-5: BBB-penetrant curcuminoid, induces ROS, DNA damage, S phase arrest, suppresses tumors in LN-18 cells.</p>Formule :C21H21NO5Couleur et forme :SolidMasse moléculaire :367.45-Aminouridine
CAS :<p>5-Aminouridine (4-Chloro-2-isopropyl-5-methylphenol(chlorothymol)) modifies nucleobases and is incorporated into the target DNA.</p>Formule :C9H13N3O6Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :259.22CDK7-IN-2
CAS :<p>CDK7-IN-2 inhibits CDK7, essential for RNA polymerase II activation and cell cycle control, with cancer research potential.</p>Formule :C26H39N7O3Couleur et forme :SolidMasse moléculaire :497.63CB10-277
CAS :<p>CB10-277 is a synthetic anti-cancer drug related to dacarbazine that alkylates DNA, inhibits DNA replication and repair, and may block DNA synthesis.</p>Formule :C9H11N3O2Couleur et forme :SolidMasse moléculaire :193.2Edatrexate
CAS :<p>Edatrexate (CGP 30694), a Methotrexate analog, combats MTX-resistant tumors and researches various cancers.</p>Formule :C22H25N7O5Couleur et forme :SolidMasse moléculaire :467.48Balamapimod
CAS :<p>Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.</p>Formule :C30H32ClN7OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :574.14HBV-IN-21
CAS :<p>HBV-IN-21 inhibits HBV DNA replication (IC50: 2.2 μM) and binds HBV capsid protein well (KD: 60.0 μM).</p>Formule :C17H17FN4OS2Couleur et forme :SolidMasse moléculaire :376.47CDK4/6-IN-7
CAS :<p>CDK4/6-IN-7 is an oral, potent CDK4/6 inhibitor with IC50s of 1.58/4.09 nM, crucial for breast cancer studies.</p>Formule :C18H18ClN5O3Couleur et forme :SolidMasse moléculaire :387.82BI8622
CAS :<p>BI8622 is a HUWE1 antagonist that restores levels of RP2 mutants in retinal cell lines and inhibits cellular activation of NLRP3 and AIM2 inflammatory vesicles.</p>Formule :C25H26N6ODegré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :426.51DHODH-IN-4
CAS :<p>DHODH-IN-4 inhibits human & Plasmodium DHODH; IC50: 4 μM (Pf), 0.18 μM (Hs). It has antimalarial properties.</p>Formule :C17H12Cl2N2O2Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :347.2Enocitabine
CAS :<p>Enocitabine is a nucleoside analog.</p>Formule :C31H55N3O6Degré de pureté :97.22%Couleur et forme :SolidMasse moléculaire :565.78CAY10760
CAS :<p>CAY10760 inhibits RAD51-BRCA2 interaction (EC50=19 μM), reduces homologous recombination by 54%, and hinders BxPC-3/Capan-1 cancer cell proliferation.</p>Formule :C28H24ClN3O3Couleur et forme :SolidMasse moléculaire :485.96SPC-839
CAS :<p>SPC-839 is an IKK-2 Inhibitor with oral activity.</p>Formule :C18H14N4O3SCouleur et forme :SolidMasse moléculaire :366.39DHODH-IN-19
CAS :<p>DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)</p>Formule :C22H18ClF6N3O3Couleur et forme :SolidMasse moléculaire :521.84ARN22089
CAS :<p>ARN22089 is an oral active CDC42 GTPase interaction inhibitor that blocks tumour growth in BRAF mutant mouse melanoma models and PDXs in vivo.</p>Formule :C23H27N5Degré de pureté :98.37%Couleur et forme :SolidMasse moléculaire :373.49αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
<p>αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).</p>Formule :C28H35F3N6O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :672.67MTH1-IN-2
CAS :<p>MTH1-IN-2 is an inhibitor of MutT homolog 1 (MTH1), with anti-tumor activity.</p>Formule :C24H27N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :469.55TH470
CAS :<p>TH470, a potent and highly selective inhibitor of LIM kinase 1/2 (LIMK1/2), demonstrates specificity with IC50 values of 9.8 nM for LIMK1 and 13 nM for LIMK2,</p>Formule :C30H31N5O5S2Couleur et forme :SolidMasse moléculaire :605.73Mequindox
CAS :<p>Mequindox is an antimicrobial agent [1]. Mequindox, as an inhibitor of DNA synthesis, induces genotoxicity and carcinogenicity in mice [2].</p>Formule :C11H10N2O3Couleur et forme :SolidMasse moléculaire :218.21Phen-DC3
CAS :<p>Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases (IC50s of 65±6 and 50±10 nM, respectively).</p>Formule :C34H26N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :550.61cp028
CAS :<p>cp028 inhibits pre-mRNA splicing in vitro.</p>Formule :C23H17FN2O4Couleur et forme :SolidMasse moléculaire :404.39Aurora kinase inhibitor-10
CAS :<p>Aurora kinase inhibitor-10 is an orally active Aurora B inhibitor (IC50: 8 nM) that exhibits antitumour effects.</p>Formule :C21H19F5N6O4SCouleur et forme :SolidMasse moléculaire :546.47Dyrk1A-IN-5
CAS :<p>Potent DYRK1A inhibitor with IC50s: 6 nM overall, 0.5 μM SF3B1, 2.1 μM tau phosphorylation. Useful for Down syndrome studies.</p>Formule :C16H9IN2O2Couleur et forme :SolidMasse moléculaire :388.16Crozbaciclib fumarate
CAS :<p>Crozbaciclib fumarate is a CDK4/6 inhibitor with IC 50 s of 3 and 1 nM, respectively.</p>Formule :C32H34F2N6O4Couleur et forme :SolidMasse moléculaire :604.65SR31527
CAS :<p>SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.</p>Formule :C15H14ClN3OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.81Antitumor agent-84
<p>Antitumor agent-84 stabilizes G-quadruplex DNA, exhibits potent anti-tumor effects.</p>Formule :C24H31N7Couleur et forme :SolidMasse moléculaire :417.55CRT-0105446
CAS :<p>CRT-0105446 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.</p>Formule :C20H18F3N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.44TCS 2312
CAS :<p>checkpoint kinase 1 (chk1) inhibitor</p>Formule :C25H24N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :412.48Trimetrexate
CAS :<p>Trimetrexate is an effective competitive inhibitor of bacterial, protozoan, and mammalian dihydrofolate reductase.</p>Formule :C19H23N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :369.42Akt1&PKA-IN-1
CAS :<p>Akt1&PKA-IN-1 inhibits Akt/PKA: IC50 = 0.03μM (PKAa), 0.11μM (Akt), 9.8μM (CDK2); selective for CDK2.</p>Formule :C20H17Cl2N3OCouleur et forme :SolidMasse moléculaire :386.27Laflunimus
CAS :<p>Laflunimus (HR325) is a DHODH inhibitor that inhibits immunoglobulin secretion in vitro and in vivo,by interfering with pyrimidine metabolism,neuralgia.</p>Formule :C15H13F3N2O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :310.275-Ethynyluridine
CAS :<p>5-Ethynyluridine marks new RNA for RICK, capturing proteins on various RNAs, even nonpolyadenylated types.</p>Formule :C11H12N2O6Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :268.22Aurora Kinases-IN-3
CAS :<p>Aurora Kinases-IN-3 is an oral AURKB inhibitor that disrupts its mitotic localization, not its H3 Ser10 phosphorylation.</p>Formule :C20H16F3N3O4Couleur et forme :SolidMasse moléculaire :419.35SRPIN-803
CAS :<p>SRPIN-803 is a selective dual SRPK1 and CK2 inhibitor.</p>Formule :C14H9F3N4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :370.31GSK317354A
CAS :<p>GSK317354A is a GRK2 inhibitor.</p>Formule :C25H18F4N6OCouleur et forme :SolidMasse moléculaire :494.44BOP sodium
CAS :<p>BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.</p>Formule :C25H29N3NaO7SCouleur et forme :SolidMasse moléculaire :538.57Integrin-IN-2
CAS :<p>Integrin-IN-2, an oral αv integrin blocker, enhances αvβ6/3/5/8 affinities with pIC50s: 7.8/8.4/8.4/7.4.</p>Formule :C27H30N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.55360A iodide
CAS :<p>360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).</p>Formule :C27H23I2N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :703.31NSC 625987
CAS :<p>Cyclin-dependent kinase (cdk) 4 inhibitor</p>Formule :C15H13NO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :271.33CDK8-IN-4
CAS :<p>CDK8-IN-4 is an inhibitor of CDK8 (IC50: 0.2 nM).</p>Formule :C20H18N4OCouleur et forme :SolidMasse moléculaire :330.38CDK12-IN-3
CAS :<p>CDK12-IN-3 is a CDK12 inhibitor with anti-tumor activity and can be used for the study of malignant tumors.</p>Formule :C23H28F2N8ODegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :470.52DNA Gyrase-IN-4
CAS :<p>DNA Gyrase-IN-4 inhibits DNA cyclooxygenase (IC50: 0.13 μM) and is effective against Salmonella and E. coli.</p>Formule :C22H15Cl2NO4SCouleur et forme :SolidMasse moléculaire :460.33FUBP1-IN-2
CAS :<p>FUBP1-IN-2 hinders FUBP1, affects c-Myc and p21 expression, and depletes polyamines.</p>Formule :C26H26ClN3O4Couleur et forme :SolidMasse moléculaire :479.96Cdc7-IN-1
CAS :<p>Cdc7-IN-1: selective ATP-competitive Cdc7 kinase inhibitor; IC50 0.6 nM at 1mM ATP; induces cancer cell death.</p>Formule :C21H16ClN3O4Couleur et forme :SolidMasse moléculaire :409.82IXA6
CAS :<p>IXA6 is an IRE1/XBP1s agonist with potential vasoprotective activity for the study of neurodegenerative diseases such as Parkinson's disease.</p>Formule :C22H20ClN3O3SDegré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :441.93KSI-3716
CAS :<p>KSI-3716 is a c-Myc inhibitor, a bladder chemotherapy agent that blocks the formation of complexes between c-MYC/MAX and target gene promoters.</p>Formule :C17H11BrCl2N2O2Degré de pureté :98.94%Couleur et forme :SolidMasse moléculaire :426.09CLK1/2-IN-3
CAS :<p>CLK1/2-IN-3 (Cpd-3) is a CLK1 and CLK2 inhibitor with antiproliferative activity that inhibits the activity of CLK and SRPK.</p>Formule :C21H21N5O2Degré de pureté :99.04%Couleur et forme :SolidMasse moléculaire :375.42CDK12-IN-E9
CAS :<p>CDK12-IN-E9 is a potent and selective covalent CDK12 inhibitor and non-covalent CDK9 inhibitor while avoiding ABC transporter-mediated efflux.</p>Formule :C24H30N6O2Couleur et forme :SolidMasse moléculaire :434.53PD-1/PD-L1-IN-NP19
CAS :<p>PD-1/PD-L1-IN-NP19: a PD-1/PD-L1 inhibitor with 12.5 nM IC50, may boost antitumor immunity.</p>Formule :C33H31ClN2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :555.06AS2863619 free base
CAS :<p>AS2863619 free base enables the conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells.</p>Formule :C16H12N8OCouleur et forme :SolidMasse moléculaire :332.325,10-Dideazaaminopterin
CAS :<p>5,10-Dideazaaminopterin is an antileukemic drug.</p>Formule :C21H22N6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.44HBV-IN-14
CAS :<p>HBV-IN-14: a pyridinopyrimidinone, potent cccDNA inhibitor for HBV study (patent WO2021190502A1, comp 5).</p>Formule :C22H21ClN2O5Couleur et forme :SolidMasse moléculaire :428.87Chlorasquin
CAS :<p>Chlorasquin is a dihydrofolate reductase inhibitor.</p>Formule :C20H19ClN6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.86Centrinone-B
CAS :<p>Centrinone-B (LCR-323) is a Plk4 inhibitor with potential anticancer activity for the study of triple-negative breast cancer.</p>Formule :C27H27F2N7O5S2Degré de pureté :98.71%Couleur et forme :SolidMasse moléculaire :631.67MMV688845
CAS :<p>MMV688845: NTM RNA polymerase inhibitor, kills Mycobacterium abscessus, and fights TB.</p>Formule :C24H25N3O3SCouleur et forme :SolidMasse moléculaire :435.54L 888607 Racemate
CAS :<p>L 888607 Racemate blocks DP1 and TP receptors with 132 nM and 17 nM affinity.</p>Formule :C19H15ClFNO2SCouleur et forme :SolidMasse moléculaire :375.84Ilorasertib hydrochloride
CAS :<p>Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s:</p>Formule :C25H22ClFN6O2SDegré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :525CLK1-IN-1
CAS :<p>CLK1-IN-1 is a potent and selective inhibitor of the Cdc2-like kinase 1 (CLK1; IC50: 2 nM).</p>Formule :C24H16FN5OCouleur et forme :SolidMasse moléculaire :409.42THZ1-R
CAS :<p>THZ1-R is a non-covalent active analogue of THZ1, with the acrylamide group removed from THZ1, not covalently bind to the C312 cysteine residue of CDK7.</p>Formule :C31H30ClN7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :568.07Antibacterial agent 124
CAS :<p>Antibacterial agent 124 inhibits Sa ProRS with an IC50 of 0.18 μM.</p>Formule :C16H17ClFN3O2Couleur et forme :SolidMasse moléculaire :337.78JA2131
CAS :<p>JA2131: Small PARG inhibitor, IC50 0.4μM, induces DNA damage, stalls replication, kills cancer cells.</p>Formule :C13H19N5O2S2Couleur et forme :SolidMasse moléculaire :341.45Poloxipan
CAS :<p>Poloxipan inhibits PLK1 (IC50: 3.2µM), PLK2 (1.7µM), PLK3 (3µM); minimal effect on Chk2, STAT1, STAT5b, Lck.</p>Formule :C14H10BrN3O3SCouleur et forme :SolidMasse moléculaire :380.22Kif15-IN-1
CAS :<p>Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.</p>Formule :C20H22N4O5SDegré de pureté :99.39% - 99.39%Couleur et forme :SolidMasse moléculaire :430.48KIF18A-IN-3
CAS :<p>KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.</p>Formule :C28H38N4O5S2Degré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :574.76BMS-688521
CAS :<p>BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.</p>Formule :C26H19Cl2N5O4Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :536.37CDK8/19-IN-51
CAS :<p>CDK8/19-IN-51 is a CDK8 and CDK19 inhibitor with anticancer activity, used in research on colorectal and gastric cancers.</p>Formule :C23H22N6O2Degré de pureté :98.65% - 99.62%Couleur et forme :SoildMasse moléculaire :414.46UR-3216
CAS :<p>UR-3216 is a prodrug, selectively antagonizing GPIIb/IIIa receptors orally, with its active form, UR-2992, binding tightly to platelets.</p>Formule :C27H29N7O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :563.56

