Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(116 produits)
- CDK(547 produits)
- Arrêt du cycle cellulaire(5 produits)
- Chk(48 produits)
- DYRK(46 produits)
- Dynamine(27 produits)
- Ferroptose(233 produits)
- HSP(180 produits)
- Intégrine(276 produits)
- Kinésine(87 produits)
- LIM Kinase(21 produits)
- Microtubules associés(273 produits)
- PKC(128 produits)
- PLK(25 produits)
- ROCK(61 produits)
- Rho(6 produits)
- Wee1(14 produits)
- c-Myc(77 produits)
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3934 produits trouvés pour "Cycle cellulaire/point de contrôle"
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5'-O-DMT-N4-Bz-5-Me-dC
CAS :5'-O-DMT-N4-Bz-5-Me-dC (DMT-NBZ-5-METHYL DC) is a modified nucleoside used in the synthesis of nucleoside phosphoramidites.Formule :C38H37N3O7Degré de pureté :98.88%Couleur et forme :SolidMasse moléculaire :647.72PolQi2
CAS :PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.Formule :C21H16ClN5O3SDegré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :453.9Ref: TM-T84770
1mg84,00€5mg170,00€1mL*10mM (DMSO)195,00€10mg281,00€25mg542,00€50mg757,00€100mg1.044,00€USP1-IN-2
CAS :USP1-IN-2 is a potent USP1 inhibitor with potential anti-tumor activity for the study of cancer.Formule :C26H22F4N6ODegré de pureté :99.69% - 99.88%Couleur et forme :SolidMasse moléculaire :510.486Tenidap
CAS :Tenidap (CP-66248) is a selective COX-1 and SLC26A3 inhibitor with anti-inflammatory, analgesic, and anti-rheumatic activities.Formule :C14H9ClN2O3SDegré de pureté :98.56% - 99.42%Couleur et forme :SolidMasse moléculaire :320.75Arg-Gly-Asp-Ser
CAS :Arg-Gly-Asp-Ser (RGDS peptide) is a conserved tetrapeptide sequence found in fibronectin, and the von Willebrand factor.Formule :C15H27N7O8Degré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :433.422'-O-(2-Methoxyethyl)adenosine
CAS :2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.Formule :C13H19N5O5Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :325.32LSN2839567
CAS :LSN2839567 (Abemaciclib metabolite M2) is a CDK4 and CDK6 inhibitor with anticancer activity, inhibits CDK9, and can be used in breast cancer research.Formule :C25H28F2N8Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :478.54DS44960156
CAS :DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.Formule :C20H15NO5Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :349.34Ref: TM-T37655
1mg73,00€5mg160,00€1mL*10mM (DMSO)170,00€10mg236,00€25mg409,00€50mg595,00€100mg858,00€Braco-19
CAS :Braco-19 is a telomerase/telomere inhibitor and an inhibitor of HAdV viral replication with antiviral activity that reduces lipid vacuolization in adipocytes, inhibits proliferation and decreases telomerase activity in human glioblastoma cells.Formule :C35H43N7O2Degré de pureté :97.01%Couleur et forme :SolidMasse moléculaire :593.765-Bromo-2',3',5'-tri-O-acetyluridine
CAS :5-Bromo-2',3',5'-tri-O-acetyluridine is a purine nucleoside analog that can be used to explore explore improve Parkinson's disease.Formule :C15H17BrN2O9Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :449.212'-O-Methyl-2-thiouridine
CAS :2'-O-Methyl-2-thiouridine, a purine nucleoside analog present in synthetic thermophilic bacterial tRNAs, is more selective for A than unmodified U.Formule :C10H14N2O5SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :274.295-Hydroxyuridine
CAS :5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue with potential antitumour activity, showing cytotoxicity against human colon adenocarcinoma cell lines.Formule :C9H12N2O7Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :260.2N6-Methyl-2'-O-methyladenosine
CAS :N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound foundFormule :C12H17N5O4Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :295.299-(β-D-Xylofuranosyl)adenine
CAS :9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine hasFormule :C10H13N5O4Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :267.24Z62954982
CAS :Z62954982 (ZINC08010136) is a Rac1 inhibitor that inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arteriesFormule :C20H21N3O5SDegré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :415.46Ref: TM-T37113
1mg35,00€5mg75,00€1mL*10mM (DMSO)87,00€10mg105,00€25mg173,00€50mg255,00€100mg371,00€200mg530,00€2'-Deoxy-N4-methylcytidine
CAS :2’-Deoxy-N4-methylcytidine (N(3)-Methyl-2'-deoxycytidine) is a purine nucleoside analog with potential antitumor activity for the study of apoptosis.Formule :C10H15N3O4Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :241.24Rabacfosadine
CAS :Rabacfosadine (GS-9219) is a novel prodrug of PMEG, an acyclic nucleotide phosphonate, with antitumor activity for the study of lymphoma.Formule :C21H35N8O6PDegré de pureté :99.06% - 99.37%Couleur et forme :SolidMasse moléculaire :526.53CDK12-IN-5
CAS :CDK12-IN-5 is a potent CDK12 inhibitor with potential anticancer and antitumor activity, and can be used orally in the study of breast and ovarian cancer.Formule :C18H15F5N8ODegré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :454.36Ref: TM-T40290
1mg157,00€5mg378,00€1mL*10mM (DMSO)416,00€10mg612,00€25mg1.251,00€50mg1.972,00€100mg2.673,00€RO0270608
CAS :RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.Formule :C24H19Cl3N2O4Degré de pureté :98.26%Couleur et forme :SolidMasse moléculaire :505.782'-Deoxy-2-iodoadenosine
CAS :2'-Deoxy-2-iodoadenosine is a purine nucleoside analog with potential antimicrobial, antioxidant and anti-leukemic activities.Formule :C10H12IN5O3Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :377.142'-Deoxy-N2-methylguanosine
CAS :2'-Deoxy-N2-methylguanosine is a purine nucleoside analog that can be used as a chemical probe to study DNA-protein interactions.Formule :C11H15N5O4Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :281.27O6-Methyldeoxy guanosine
CAS :O6-Methyldeoxy guanosine, a deoxypurine nucleoside, is a weak inhibitor of the removal of O6-methylguanine from methylated DNA by rat liver enzymes in vitro.Formule :C11H15N5O4Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :281.27N6-(p-Methoxybenzyl)adenosine
CAS :Nucleoside Derivatives - 6-Modified purine nucleosides; Drugs and Inhibitors; plant growth regulator, plant hormoneFormule :C18H21N5O5Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :387.39Ref: TM-TNU0430
1mg141,00€2mg203,00€5mg344,00€10mg505,00€25mg797,00€50mg1.044,00€100mg1.431,00€200mg1.953,00€Levomefolate sodium
CAS :Levomefolate sodium (L-5-MTHF sodium) is a dietary supplement that can be used to study megaloblastic anemia and neurological disorders.Formule :C20H23N7Na2O6Degré de pureté :98.7%Couleur et forme :SolidMasse moléculaire :503.42PF-03814735
CAS :PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.Formule :C23H25F3N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :474.48SCH-1473759 hydrochloride
CAS :SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).Formule :C20H27ClN8OSDegré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :463Mps1-IN-2
CAS :Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.Formule :C26H36N6O3Degré de pureté :96.24% - 99.75%Couleur et forme :SolidMasse moléculaire :480.6MK-5108
CAS :MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.Formule :C22H21ClFN3O3SDegré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :461.945-Methyl-5,6-dihydrouridine
CAS :5-Methyl-5,6-dihydrouridine is a minor constituent in the chromosomal RNA of the rat ascites tumor. It can be used for nucleic acid modification.Formule :C10H16N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :260.24Pavurutamab
CAS :Pavurutamab (AMG-701) is a bispecific T cell engager targeting CD3 and BCMA with extended half-life, designed to treat MM.Couleur et forme :LiquidN6-Etheno 2'-deoxyadenosine
CAS :N6-Etheno 2'-deoxyadenosine is used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues.Formule :C12H13N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :275.26Acapatamab
CAS :Acapatamab (AMG-160) is a Half-Life Extended (HLE) Bispecific T-cell Engager (BiTE) with domains that bind to PSMA and CD3. It exhibits Kd values of 14.8 nM for hPSMA and 22.4 nM for hCD3. This compound is utilized in cancer research.Couleur et forme :LiquidOS-2966
OS-2966 is a humanised de-immunised monoclonal antibody that target Integrin b1/ITGB1/CD29, malignant gliomas, glioblastomas, and astrocytomas.Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :~150 kDaIluzanebart
CAS :Iluzanebart, a hTREM2 agonist antibody, enhances microglial survival and function, modeling CSF1R-ALSP and microglial dysfunction in neurodegenerative studies.Degré de pureté :95% - 97.7% (SDS-PAGE); 98.3% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :144.90 kDaAnti-Mouse CD32/CD16 Antibody (2.4G2)
Anti-Mouse CD32/CD16 Antibody is a rat-derived IgG2b inhibitor targeting the mouse CD32/CD16 antigens.Couleur et forme :Odour LiquidMasse moléculaire :150 kDaGresonitamab
CAS :Gresonitamab (AMG 910) is an HLE BiTE antibody targeting CD3+ T cells and CLDN18.2+ tumors, for adenocarcinoma research.Couleur et forme :LiquidVibecotamab
CAS :Vibecotamab, a bispecific antibody, targets CD123/CD3 for T-cell killing of tumors, promising for acute myeloid leukemia.Couleur et forme :LiquidGSK4418959
CAS :GSK4418959 (IDE275) is a selective WRN helicase inhibitor that blocks ATPase and DNA unwinding, serving as a tool in MSI-H cancer research.Formule :C31H30F4N4O5SDegré de pureté :99.141%Couleur et forme :SoildMasse moléculaire :646.65Caplacizumab
CAS :Caplacizumab (ALX-0681), a humanized anti-von Willebrand factor (vWF) nanobody, serves to impede vWF-mediated platelet adhesion, thereby averting additionalCouleur et forme :LiquidAlnuctamab
CAS :Alnuctamab (EM901) is a humanized, asymmetric two-arm IgG T-cell engager (TCE) with potential applications in immunological research [1].Couleur et forme :LiquidPOSH-IN-1
CAS :POSH-IN-1 (Compound 108) is an inhibitor of the POSH polypeptide （e3 ligase) and has antiviral, anticancer, and neurodegenerative disease potential.Formule :C14H8FNO3SDegré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :289.28Locked nucleic acid 1
CAS :Locked nucleic acid 1 is an LNA-type nucleoside derivative.Formule :C32H32N2O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :572.61Viltolarsen
CAS :Viltolarsen targets exon 53 in the dystrophin gene for Duchenne muscular dystrophy research.Couleur et forme :SolidMetribuzin
CAS :Metribuzin is a selective herbicide used on crops like soybeans and potatoes. It inhibits photosynthesis and is a persistent groundwater contaminant.
Formule :C8H14N4OSDegré de pureté :99.07%Couleur et forme :Colorless Crytals Metribuzin Is A Colorless Crystalline Solid Used As An Herbicide (Niosh 2016)Masse moléculaire :214.29Enlimomab
CAS :Enlimomab (BI-RR 0001), a mouse IgG2a antibody, blocks leukocyte binding to ICAM-1, reducing inflammation and used in stroke research.Couleur et forme :LiquidDHX9-IN-8
CAS :DHX9-IN-8 (Compound 6) functions as an inhibitor of the RNA helicase DHX9, exhibiting an EC50 of 3.4 μM for cellular target engagement within DHX9. It is primarily utilized in cancer research [1].Formule :C18H16N2O3S2Couleur et forme :SolidMasse moléculaire :372.46Rovelizumab
CAS :Rovelizumab, Humanized anti-CD11/CD18 mAb, inhibits overactive leukocytes during shock, for MS, hemorrhagic shock, myocardial infarction, and stroke.Degré de pureté :95% - 95%Couleur et forme :LiquidRinatabart
CAS :Rinatabart is a humanised monoclonal antibody targeting FRα/FOLR1, suitable for investigating ovarian and endometrial cancers expressing FRα.Degré de pureté :95% - 95.7% (SDS-PAGE); 96.0% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.18 kDaAnti-Mouse TCR γ/δ Antibody (UC7-13D5)
Anti-Mouse TCR gamma/delta Antibody is a host Armenian Hamster-derived IgG class inhibitor targeting the mouse TCR gamma/delta receptor.Couleur et forme :Odour LiquidObrindatamab
CAS :Obrindatamab: a humanized bispecific antibody targeting B7-H3/CD3, enhances CTL-mediated cancer cell killing.Couleur et forme :LiquidVonsetamig
CAS :Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.Couleur et forme :LiquidPacanalotamab
CAS :Pacanalotamab (AMG 420/BI-836909), a BiTE, directs T-cells to BCMA+ MM cells, causing lysis.Couleur et forme :LiquidVatelizumab
CAS :Vatelizumab is a humanised monoclonal antibody targeting Integrin α2β1 ( VLA-2, CD49b), which enhances the frequency of regulatory T cells multiple sclerosis.Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :~150 kDaLinvoseltamab
CAS :Linvoseltamab, a bispecific antibody, targets both BCMA (TNFRSF17) and CD3 epsilon, demonstrating a favorable safety profile and promising efficacy in relapsed/Couleur et forme :LiquidPasotuxizumab
CAS :Pasotuxizumab (BAY 2010112) is a BiTE that targets PSMA & CD3 with K D s 47.0 & 9.4 nM, for mCRPC research.Couleur et forme :LiquidVepsitamab
CAS :Vepsitamab (AMG 199), an anti-MUC17/CD3 BiTE, targets T cells and tumors for cell lysis and T cell activation.Couleur et forme :LiquidVVD-214
CAS :VVD-214 (RO7589831) is a WRN deconjugation enzyme lethal-mutagenic inhibitor that can be used to study proliferative diseases.Formule :C20H21F2N3O4SDegré de pureté :99.24% - 99.93%Couleur et forme :SoildMasse moléculaire :437.46Ref: TM-T85309
1mg69,00€5mg147,00€1mL*10mM (DMSO)164,00€10mg224,00€25mg358,00€50mg512,00€100mg707,00€Vixtimotamab
Vixtimotamab (AMV-564; TandAb T564), a bispecific tetravalent tandem diabody (TandAb), selectively engages human CD33 and CD3 antigens.Couleur et forme :Odour LiquidFlotetuzumab
CAS :Flotetuzumab (MGD006/S80880) is a CD123/CD3 bispecific DART antibody, reactivating T-cells for AML treatment.Couleur et forme :LiquidTepoditamab
CAS :Tepoditamab (MCLA-117) is a bispecific antibody targeting CLEC12A and CD3, inducing T cell lysis of AML cells.Couleur et forme :LiquidUbamatamab
CAS :Ubamatamab (REGN4018), a human bispecific antibody targeting Mucin 16 (MUC16) and CD3, exhibits potent antitumor activity [1].Degré de pureté :95%Couleur et forme :LiquidAnti-Mouse CD3ε Antibody (145-2C11)
Anti-Mouse CD3ε Antibody (145-2C11) is an antibody inhibitor targeting CD3ε in Armenian hamsters, in TCR formation and in T lymphocyte activationDegré de pureté :99%Couleur et forme :Odour LiquidMasse moléculaire :150 kDaVoxalatamab
CAS :Voxalatamab (JNJ-63898081), an IgG4 bispecific antibody targeting PSMA and CD3, demonstrates anti-cancer efficacy in prostate cancer research [1].Couleur et forme :LiquidTilatamig samrotecan
Tilatamig samrotecan (AZD9592) is an antibody-drug conjugate (ADC) designed to deliver a topoisomerase I inhibitor (TOP1i). It targets epidermal growth factor receptor (EGFR) and c-MET and demonstrates antitumor activity. The compound induces DNA double-strand breaks, elevates pRAD50 and γH2AX expression, and inhibits the growth of non-small cell lung cancer.Couleur et forme :Odour SolidhDHODH-IN-2
CAS :hDHODH-IN-2: Leflunomide metabolite analog, inhibits human dihydroorotate dehydrogenase, anti-inflammatory.Formule :C19H16N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :304.349L-Threonolactone
CAS :L-Threonolactone is a Carbohydrate Derivative.Formule :C4H6O4Couleur et forme :SolidMasse moléculaire :118.09Adenosine 2'-PEG-Biotin
CAS :Adenosine 2'-PEG-Biotin, a bioreagent derived from adenosine, modulates cellular signaling pathways by mimicking the action of endogenous adenosine and binding to its receptors. This compound is used in research related to bioprobes, biosensors, and diagnostic agents.Formule :C26H40N8O8SCouleur et forme :SolidMasse moléculaire :624.71MC-1-F2
CAS :MC-1-F2 is a direct FOXC2 inhibitor with anticancer activity and inhibits cancer stem cell (CSC) properties and can be used to study prostate cancer.Formule :C37H46N16O2Degré de pureté :97.31% - 98.44%Couleur et forme :SolidMasse moléculaire :746.87(R)-(+)-O-Demethylbuchenavianine
CAS :(R)-(+)-O-Demethylbuchenavianine is a cyclin-dependent kinase (CDK) inhibitor. It inhibits CDK1, CDK5, glycogen synthase kinase 3 (GSK3), cdc2-like kinase (CLK1), and dual-specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) with IC50 values of 1.1 μM, 0.95 μM, >10 μM, >10 μM, and >10 μM, respectively.Formule :C21H21NO4Couleur et forme :SolidMasse moléculaire :351.402'-Azido-2'-deoxyuridine
CAS :2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor with anti-cancer activity.Formule :C9H11N5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :269.21Mirvetuximab soravtansine
CAS :Mirvetuximab soravtansine (IMGN853) is an antibody-drug coupling that targets FRα, inhibits cell growth, and can be used to study drug-resistant ovarian cancerDegré de pureté :6mg/ml - 95.52% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.76 kDaSB273005
CAS :SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.Formule :C22H24F3N3O4Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :451.44E-982
CAS :E-982 is derived from the reference compound.Formule :C25H31NO6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.58RI(dl)-2 TFA
CAS :RI(dl)-2 TFA inhibits RAD51 D-loop at 11.1 μM and HR in human cells at 3.0 μM.Formule :C19H17N3Couleur et forme :SolidMasse moléculaire :287.363,4-Dihydroxybenzylamine hydrobromide
CAS :3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.Formule :C7H10BrNO2Degré de pureté :98.49%Couleur et forme :Light Beige Crystalline PowderMasse moléculaire :220.06XL413
CAS :XL-413 is an oral CDC7 kinase inhibitor, potentially blocking DNA replication, mitosis, and cancer cell growth.Formule :C14H12ClN3O2Degré de pureté :98.40% - 99.94%Couleur et forme :SolidMasse moléculaire :289.72BAY1217389
CAS :BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).Formule :C27H24F5N5O3Degré de pureté :98.14% - 99.42%Couleur et forme :SolidMasse moléculaire :561.5Tirofiban
CAS :Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.Formule :C22H36N2O5SDegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :440.6Mps1-IN-1
CAS :Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )Formule :C28H33N5O4SDegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :535.66TAK-285
CAS :TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc.Formule :C26H25ClF3N5O3Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :547.96Ref: TM-T6039
1mg38,00€5mg80,00€1mL*10mM (DMSO)96,00€10mg120,00€25mg216,00€50mg354,00€100mg512,00€200mg727,00€GW843682X
CAS :GW843682X (GW843682) is a selective and ATP-competitive inhibitor of PLK1 and PLK3 (IC50s = 2.2 nM and 9.1 nM).Formule :C22H18F3N3O4SDegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :477.46Rabacfosadine succinate
CAS :Rabacfosadine succinate is the acyclic nucleoside phosphonate PMEG double prodrug.Formule :C25H41N8O10PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :644.623Aloisine B
CAS :Aloisine B (AloisineB) inhibited cyclin-dependent kinase and glycogen synthase kinase with IC50 values of 0.85 µM and 0.75 µM, respectively.Formule :C15H14ClN3Degré de pureté :95.15%Couleur et forme :SolidMasse moléculaire :271.74IACS-4759
CAS :IACS-4759 is a novel potent and selective MTH1 inhibitor with excellent cell permeability and good metabolic stability in microsomes.Formule :C10H17N3O2Couleur et forme :SolidMasse moléculaire :211.26BMH-22
CAS :BMH-22 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.Formule :C16H17N3Couleur et forme :SolidMasse moléculaire :251.33DHODH-IN-3
CAS :DHODH-IN-3: Human DHODH inhibitor with IC50 of 261 nM, Kiapp 32 nM, potential anti-malaria drug.Formule :C17H13ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :312.75HBV-IN-14
CAS :HBV-IN-14: a pyridinopyrimidinone, potent cccDNA inhibitor for HBV study (patent WO2021190502A1, comp 5).Formule :C22H21ClN2O5Couleur et forme :SolidMasse moléculaire :428.87CDK2-IN-12
CAS :CDK2-IN-12 (10b), potent CDK2 inhibitor, IC50: 11.6 μM; inhibits hCA I/II/IX/XII, KI: 3534/638.4/44.3/48.8 nM; anti-cancer properties.Formule :C20H17N9O2SCouleur et forme :SolidMasse moléculaire :447.47BMS-986463
CAS :BMS-986463 is a WEE1 kinase molecule gel degrader and a CRBN E3 ligase regulator (CELMoD). BMS-986463 significantly inhibits tumor regression and reduces the level of phosphorylated CDK2. BMS-986463 can be used in the research of advanced malignant solid tumors such as non-small cell lung cancer (NSCLC).Formule :C32H33FN4O5Couleur et forme :SolidMasse moléculaire :572.63IRE1α kinase-IN-9
CAS :IRE1α kinase-IN-9 (compound 2) is a potent inhibitor of IRE-1α, demonstrating an average IC50 value of less than 0.1 μM.Formule :C24H24N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.46DHODH-IN-13
CAS :DHODH-IN-13 is an inhibitor of DHODH with IC50 of 4.3 μM for rat liver. DHODH-IN-13 can be used in studies about rheumatoid arthritis.Formule :C10H6F3N3O3Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :273.17Type II topoisomerase inhibitor 1
CAS :Potent E. coli DNA gyrase inhibitor (IC50: 1.7 nM), targets Asp73; weak topoisomerase IV inhibitor (IC50: 0.98 μM).Formule :C18H15N3O4Couleur et forme :SolidMasse moléculaire :337.33(S)-CR8
CAS :(S)-CR8 is an effective second-generation cyclin-dependent kinase inhibitor.Formule :C24H29N7OCouleur et forme :SolidMasse moléculaire :431.53Ulecaciclib
CAS :Ulecaciclib: oral, BBB-permeable CDK inhibitor; favorable pharmacokinetics; ki: 0.62 μM (CDK2/A), 3 nM (CDK6/D3), 0.2 nM (CDK4/D1), 0.63 μM (CDK7/H).Formule :C25H33FN8SCouleur et forme :SolidMasse moléculaire :496.65hDHODH-IN-3
CAS :hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.Formule :C18H19BrN4O2Degré de pureté :99.871%Couleur et forme :SolidMasse moléculaire :403.27Ref: TM-T11025
500mgÀ demander1mg60,00€2mg88,00€5mg133,00€1mL*10mM (DMSO)142,00€10mg203,00€25mg335,00€50mg474,00€100mg623,00€Sibrafiban
CAS :Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.Formule :C20H28N4O6Couleur et forme :SolidMasse moléculaire :420.46VRX-0466617
CAS :VRX-0466617 is a novel selective Chk2 inhibitor.Formule :C19H20BrN5O2SCouleur et forme :SolidMasse moléculaire :462.36Cdc7-IN-13
CAS :Cdc7-IN-13 (compound 84) is a highly potent CDC7 inhibitor, exhibiting an IC50 value of <1 nM. This compound holds promise for cancer research [1].Formule :C18H20N4O2SCouleur et forme :SolidMasse moléculaire :356.44Carbonic anhydrase inhibitor 14
CAS :CA inhibitor 14 blocks hCA I/II/IX/XII (K i of 1203/99.7/9.4/27.7 nM) and CDK2 (IC50: 20.3 μM), showing antitumor effects.Formule :C18H17N7O2SCouleur et forme :SolidMasse moléculaire :395.44OM-137
CAS :OM137 inhibits Aurora kinases, impedes cell growth at high doses, and enhances low-dose paclitaxel effects.Formule :C13H14N4O3SCouleur et forme :SolidMasse moléculaire :306.34
