
Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(116 produits)
- CDK(547 produits)
- Arrêt du cycle cellulaire(5 produits)
- Chk(48 produits)
- DYRK(46 produits)
- Dynamine(27 produits)
- Ferroptose(227 produits)
- HSP(180 produits)
- Intégrine(276 produits)
- Kinésine(87 produits)
- LIM Kinase(21 produits)
- Microtubules associés(273 produits)
- PKC(127 produits)
- PLK(25 produits)
- ROCK(61 produits)
- Rho(6 produits)
- Wee1(14 produits)
- c-Myc(77 produits)
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3923 produits trouvés pour "Cycle cellulaire/point de contrôle"
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DNA Gyrase-IN-4
CAS :DNA Gyrase-IN-4 inhibits DNA cyclooxygenase (IC50: 0.13 μM) and is effective against Salmonella and E. coli.Formule :C22H15Cl2NO4SCouleur et forme :SolidMasse moléculaire :460.33FUBP1-IN-2
CAS :FUBP1-IN-2 hinders FUBP1, affects c-Myc and p21 expression, and depletes polyamines.Formule :C26H26ClN3O4Couleur et forme :SolidMasse moléculaire :479.96SR31527
CAS :SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.Formule :C15H14ClN3OSDegré de pureté :98.52%Couleur et forme :SolidMasse moléculaire :319.81Ref: TM-T28848
1mg63,00€5mg137,00€1mL*10mM (DMSO)145,00€10mg215,00€25mg439,00€50mg708,00€100mg1.144,00€5,10-Dideazaaminopterin
CAS :5,10-Dideazaaminopterin is an antileukemic drug.Formule :C21H22N6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.44HBV-IN-14
CAS :HBV-IN-14: a pyridinopyrimidinone, potent cccDNA inhibitor for HBV study (patent WO2021190502A1, comp 5).Formule :C22H21ClN2O5Couleur et forme :SolidMasse moléculaire :428.87MMV688845
CAS :MMV688845: NTM RNA polymerase inhibitor, kills Mycobacterium abscessus, and fights TB.Formule :C24H25N3O3SCouleur et forme :SolidMasse moléculaire :435.54Tenofovir exalidex
CAS :Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistantFormule :C28H52N5O5PDegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :569.72BPIC
CAS :BPIC is an agent of anti-tumor that acts by inhibiting inflammation and scavenging free radicals.Formule :C27H20N2O5Couleur et forme :SolidMasse moléculaire :452.465-Ethynyluridine
CAS :5-Ethynyluridine marks new RNA for RICK, capturing proteins on various RNAs, even nonpolyadenylated types.Formule :C11H12N2O6Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :268.22Ref: TM-T36971
5mg49,00€1mL*10mM (DMSO)54,00€10mg84,00€25mg138,00€50mg236,00€100mg344,00€200mg515,00€Antibacterial agent 124
CAS :Antibacterial agent 124 inhibits Sa ProRS with an IC50 of 0.18 μM.Formule :C16H17ClFN3O2Couleur et forme :SolidMasse moléculaire :337.78CDK9-IN-15
CAS :CDK9-IN-15: potent CDK9 inhibitor, blocks P-TEFb phosphorylation, inhibits transcription, reduces mRNA, induces tumor cell apoptosis.Formule :C16H11N3OSDegré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :293.34Ref: TM-T60619
1mL*10mM (DMSO)44,00€5mg46,00€10mg71,00€25mg126,00€50mg180,00€100mg260,00€200mg364,00€JA2131
CAS :JA2131: Small PARG inhibitor, IC50 0.4μM, induces DNA damage, stalls replication, kills cancer cells.Formule :C13H19N5O2S2Couleur et forme :SolidMasse moléculaire :341.45Poloxipan
CAS :Poloxipan inhibits PLK1 (IC50: 3.2µM), PLK2 (1.7µM), PLK3 (3µM); minimal effect on Chk2, STAT1, STAT5b, Lck.Formule :C14H10BrN3O3SCouleur et forme :SolidMasse moléculaire :380.22CTP Synthetase-IN-1
CAS :CTP Synthetase-IN-1 is a cytidine 5'-triphosphate synthetase (CTPS) inhibitor with antitumor activity for the study of arthritis and rheumatoid arthritis.Formule :C20H19F3N6O3S2Degré de pureté :98.11% - 99.18%Couleur et forme :SolidMasse moléculaire :512.53Ref: TM-T72505
1mg65,00€5mg141,00€1mL*10mM (DMSO)158,00€10mg230,00€25mg477,00€50mg803,00€100mg1.378,00€RSK-IN-1
CAS :RSK-IN-1 (compound 7d) shows anti-tumor activity. RSK-IN-1 is an inhibitor of RSK that inhibits the phosphorylation of YB-1 [1].Formule :C22H17NO2Couleur et forme :SolidMasse moléculaire :327.38CDK8-IN-4
CAS :CDK8-IN-4 is an inhibitor of CDK8 (IC50: 0.2 nM).Formule :C20H18N4OCouleur et forme :SolidMasse moléculaire :330.38CLK1-IN-2
CLK1-IN-2: Metabolically stable, Clk1-selective inhibitor; IC50=1.7nM; useful in tumor, Duchenne MD, HIV-1, influenza research.Formule :C16H12Cl2N2O2SCouleur et forme :SolidMasse moléculaire :367.25CDK12-IN-3
CAS :CDK12-IN-3 is a CDK12 inhibitor with anti-tumor activity and can be used for the study of malignant tumors.Formule :C23H28F2N8ODegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :470.52Ref: TM-T14990
1mg101,00€5mg245,00€1mL*10mM (DMSO)254,00€10mg401,00€25mg842,00€50mg1.701,00€100mg2.250,00€Cdc7-IN-1
CAS :Cdc7-IN-1: selective ATP-competitive Cdc7 kinase inhibitor; IC50 0.6 nM at 1mM ATP; induces cancer cell death.Formule :C21H16ClN3O4Couleur et forme :SolidMasse moléculaire :409.82TDRL-X80
CAS :TDRL-X80 inhibits XPA DNA binding; effective on single, double, and cisplatin-damaged DNA; IC50: 18-29 μM (FP), 21-39 μM (ELISA).Formule :C23H15ClN2O6Couleur et forme :SolidMasse moléculaire :450.83CCG-257081
CAS :CCG-257081 blocks Rho/MRTF/SRF pathway; prevents fibrosis in mice; useful in cancer and fibrosis research.Formule :C24H19ClF3N3O2Degré de pureté :99.60% - 99.94%Couleur et forme :SolidMasse moléculaire :473.87CLK1/2-IN-3
CAS :CLK1/2-IN-3 (Cpd-3) is a CLK1 and CLK2 inhibitor with antiproliferative activity that inhibits the activity of CLK and SRPK.Formule :C21H21N5O2Degré de pureté :99.04%Couleur et forme :SolidMasse moléculaire :375.42CDK12-IN-E9
CAS :CDK12-IN-E9 is a potent and selective covalent CDK12 inhibitor and non-covalent CDK9 inhibitor while avoiding ABC transporter-mediated efflux.Formule :C24H30N6O2Couleur et forme :SolidMasse moléculaire :434.53AS2863619 free base
CAS :AS2863619 free base enables the conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T (Treg) cells.Formule :C16H12N8OCouleur et forme :SolidMasse moléculaire :332.32Centrinone-B
CAS :Centrinone-B (LCR-323) is a Plk4 inhibitor with potential anticancer activity for the study of triple-negative breast cancer.Formule :C27H27F2N7O5S2Degré de pureté :98.71%Couleur et forme :SolidMasse moléculaire :631.67SP-471P
CAS :SP-471P inhibits DENV protease; EC50: DENV1-5.9 μM, DENV2-1.4 μM, DENV3-5.1 μM, DENV4-1.7 μM; CC50 >100 μM; lowers viral RNA synthesis.Formule :C33H26BrN5O2Couleur et forme :SolidMasse moléculaire :604.5Crisnatol
CAS :Crisnatol (BWA770U) is an oral anticancer DNA intercalator, toxic to breast cancer cells, not skin fibroblasts.Formule :C23H23NO2Couleur et forme :SolidMasse moléculaire :345.43L 888607 Racemate
CAS :L 888607 Racemate blocks DP1 and TP receptors with 132 nM and 17 nM affinity.Formule :C19H15ClFNO2SCouleur et forme :SolidMasse moléculaire :375.84Ilorasertib hydrochloride
CAS :Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s:Formule :C25H22ClFN6O2SDegré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :525CLK1-IN-1
CAS :CLK1-IN-1 is a potent and selective inhibitor of the Cdc2-like kinase 1 (CLK1; IC50: 2 nM).Formule :C24H16FN5OCouleur et forme :SolidMasse moléculaire :409.42Cdc7-IN-17
CAS :Cdc7-IN-17 is a potent inhibitor of CDC7 with an IC 50 of <10 μM that can be used in cancer research [1].Formule :C13H15N5OSCouleur et forme :SolidMasse moléculaire :289.36THZ1-R
CAS :THZ1-R is a non-covalent active analogue of THZ1, with the acrylamide group removed from THZ1, not covalently bind to the C312 cysteine residue of CDK7.Formule :C31H30ClN7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :568.07IXA6
CAS :IXA6 is an IRE1/XBP1s agonist with potential vasoprotective activity for the study of neurodegenerative diseases such as Parkinson's disease.Formule :C22H20ClN3O3SDegré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :441.9310-Formyl-5,8-dideazafolic acid
CAS :10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor.Formule :C22H21N5O7Degré de pureté :96.04%Couleur et forme :SolidMasse moléculaire :467.43BPKDi
CAS :BPKDi is a potent and selective inhibitor of PKD (protein kinase D).Formule :C21H28N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :380.49Aloisine A
CAS :Aloisine A, a CDK/GSK-3 inhibitor with IC50: Cdk1/B-150nM, Cdk2/A-120nM, Cdk2/E-400nM, Cdk5/25-200nM, Cdk5/35-160nM, GSK-3α-500nM, GSK-3β-650nM, JNK-3-10μM.Formule :C16H17N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :267.33Kif15-IN-1
CAS :Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.Formule :C20H22N4O5SDegré de pureté :99.39% - 99.39%Couleur et forme :SolidMasse moléculaire :430.48KIF18A-IN-3
CAS :KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.Formule :C28H38N4O5S2Degré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :574.763'-Deoxyuridine-5'-triphosphate
CAS :3'-dUTP, a nucleotide analogue, competitively inhibits RNA polymerases I & II, with a Ki of 2.0 µM.Formule :C9H15N2O14P3Couleur et forme :SolidMasse moléculaire :468.14CDK8/19-IN-51
CAS :CDK8/19-IN-51 is a CDK8 and CDK19 inhibitor with anticancer activity, used in research on colorectal and gastric cancers.Formule :C23H22N6O2Degré de pureté :98.65% - 99.62%Couleur et forme :SoildMasse moléculaire :414.46CDK8-IN-7
CAS :CDK8-IN-7 is a potent CDK8 inhibitor with a Kd of 3.5 nM, showing promise for AML research.Formule :C30H40N2Couleur et forme :SolidMasse moléculaire :428.65XVA143
CAS :XVA143 is an integrin α/β I-like allosteric antagonist, inhibits LFA-1 (αLβ2 integrin)-dependent firm adhesion, induces extended conformations of integrins.Formule :C25H21Cl2N3O8Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :562.36HBV-IN-4
CAS :HBV-IN-4, a phthalazinone, inhibits HBV DNA replication orally (IC50: 14 nM), encouraging genome-free capsids with strong anti-HBV effects.Formule :C24H19ClFN5O3Couleur et forme :SolidMasse moléculaire :479.89MLAF50
CAS :MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.Formule :C15H12I2O4Couleur et forme :SolidMasse moléculaire :510.06Cdc7-IN-15
CAS :Cdc7-IN-15 (Example 108) is an inhibitor of cdc7 kinase that has potential to be used for cancer research [1].Formule :C12H14N4OSCouleur et forme :SolidMasse moléculaire :262.33CP681301
CAS :CP681301 is a potent CDK5 inhibitor with anti-tumor effects in Drosophila and reduces Glioma stem cells' growth and renewal.Formule :C17H22N4OCouleur et forme :SolidMasse moléculaire :298.38DNA Gyrase-IN-2
CAS :DNA Gyrase-IN-2 inhibits E. coli (IC50: 3.29-10.49 μM) and M. tuberculosis (IC50: 4.41-5.61 μM) COX, has antibacterial properties.Formule :C24H24N8OS2Couleur et forme :SolidMasse moléculaire :504.63TP1287
CAS :TP-1287 is an oral phosphate prodrug of the CDK9 inhibitor, alvocidib.Formule :C21H21ClNO8PCouleur et forme :SolidMasse moléculaire :481.82BMS-688521
CAS :BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.Formule :C26H19Cl2N5O4Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :536.37Ref: TM-T14676
1mg108,00€5mg264,00€1mL*10mM (DMSO)311,00€10mg371,00€25mg665,00€50mg874,00€100mg1.063,00€200mg1.423,00€CDK7-IN-15
CAS :CDK7-IN-15 (Compound 8) is an effective CDK7 inhibitor for studying cancers associated with transcriptional dysregulation.Formule :C21H24F4N6OSDegré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :484.51Braco-19 trihydrochloride
CAS :BRACO19 3HCl inhibits telomerase, blocking its capping function, and prevents HAdV viral replication.Formule :C35H46Cl3N7O2Degré de pureté :98.74%Couleur et forme :SolidMasse moléculaire :703.14Laromustine
CAS :Laromustine (VNP40101M) is a sulfonyl hydrolysis alkylation prodrug for cancer treatment with significant anticancer activity, inhibiting thioredoxin reductase.Formule :C6H14ClN3O5S2Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :307.78Beaucage reagent
CAS :Beaucage reagent, which is found to be effective in causing DNA cleavage.Formule :C7H4O3S2Degré de pureté :98.50%Couleur et forme :White To Off-White PowderMasse moléculaire :200.23CBL 0100 free base
CAS :CBL0100 is an inhibitor of viral transcriptional elongation, blocking both HIV-1 replication and reactivation.Formule :C24H26N2O2Degré de pureté :98.18% - 98.86%Couleur et forme :SolidMasse moléculaire :374.48APC 366
CAS :APC 366: Mast cell tryptase inhibitor, Ki 7.1 μM. Reduces EAR, LAR, BHR in allergic asthma (sheep model).Formule :C22H28N6O4Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :440.5GW8510
CAS :GW8510 is a CDK2 and RRM2 inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 prolongs lifespan.Formule :C21H15N5O3S2Degré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :449.51CH-1504
CAS :CH-1504, dihydrofolate reductase (DHFR) inhibitor, is used potentially for the treatment of rheumatoid arthritis.Formule :C23H23N5O5Couleur et forme :SolidMasse moléculaire :449.46IDD388
CAS :IDD388 is a selective and potent aldose reductase (ALR2) inhibitor with antitumor activity that inhibits the ALR1 receptor.Formule :C16H12BrClFNO4Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :416.63MMV688844
CAS :MMV688844 inhibits M. abscessus DNA cyclooxygenase (IC50: 2μM) and has MIC50 of 12μM on strain bamboo; useful in antimicrobial studies.Formule :C23H25ClN4O2Couleur et forme :SolidMasse moléculaire :424.92CDK7-IN-10
CAS :CDK7-IN-10: CDK7 inhibitor, IC50<100 nM, may hinder cell growth, induce apoptosis. (Patent WO2021016388A1, I-1)Formule :C29H35N7O3Couleur et forme :SolidMasse moléculaire :529.63CDK7-IN-16
CAS :CDK7-IN-16, a potent CDK7 inhibitor (IC50: 1-10 nM), is used in cancer research with transcription defects.Formule :C19H21F3N6O2SCouleur et forme :SolidMasse moléculaire :454.47DHX9-IN-1
CAS :DHX9-IN-1 is a potent ATP-dependent RNA helicase A (DHX9) inhibitor, exhibiting an IC50 of 9.45 nM and demonstrating antitumor activity [1].Formule :C21H21F2N5O3SCouleur et forme :SolidMasse moléculaire :461.49Ref: TM-T82569
1mg205,00€5mg528,00€1mL*10mM (DMSO)537,00€10mg782,00€25mg1.161,00€50mg1.558,00€100mg2.322,00€WNK1-IN-1
CAS :WNK1-IN-1, a WNK1 inhibitor (IC50: 1.6 μM), also inhibits OSR1 phosphorylation (IC50: 4.3 μM), used in blood pressure and cancer research.Formule :C13H15BrCl2N2O4SDegré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :446.14Ref: TM-T73295
1mg71,00€5mg152,00€1mL*10mM (DMSO)167,00€10mg236,00€25mg485,00€50mg782,00€100mg1.305,00€DENV-IN-4
CAS :DENV-IN-4: Effective DENV inhibitor (EC50=4.79 μM), low toxicity (CC50>100 μM), and strong selectivity (SI>20.9); suppresses DENV2 and RdRp.Formule :C28H32N4O4SiCouleur et forme :SolidMasse moléculaire :516.66Valategrast hydrochloride
CAS :Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.Formule :C30H33Cl4N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :641.41CDK9-IN-14
CAS :CDK9-IN-14: Potent CDK9 inhibitor, IC50=6.92 nM, effective on MV-4-11 cells and in vivo tumors, low toxicity, minimal side effects.Formule :C21H23F2N3O4Couleur et forme :SolidMasse moléculaire :419.42Synucleozid
CAS :Synucleozid is a potent the SNCA mRNA inhibitor that encodes α-synuclein protein (IC50=1.5 μM), has the potential for the investigation of Parkinson’s disease.Formule :C22H20N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :368.43PF-4950834
CAS :PF-4950834, a ATP-competitive, selective Rho kinase inhibitor, provides therapeutic benefits in chronic inflammatory diseases.Formule :C21H19N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :345.39PV-1115
CAS :PV-1115 is an effective and highly selective inhibitor of the Chk2.Formule :C20H19N7O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :405.41HIV-1 inhibitor-43
CAS :HIV-1 Inhibitor-43 suppresses HIV-1, with EC50: 21.3 nM (Y188L), 6.2 nM (K103N-Y181C), <0.7 nM (K103N/Y181C), and lowers HIV RNA/p24 protein.Formule :C24H21ClN2O4SCouleur et forme :SolidMasse moléculaire :468.95(Rac)-Managlinat dialanetil
CAS :Managlinat dialanetil, an orally available and potent inhibitor of fructose 1,6-bisphosphatase (FBPase) used in research 2 type diabetes.Formule :C21H33N4O6PSDegré de pureté :98.52%Couleur et forme :SolidMasse moléculaire :500.55FAK/aurora kinase-IN-1
CAS :FAK/aurora kinase-IN-1, a dual inhibitor of FAK and aurora kinase, has IC50 values of 6.61 nM and 0.91 nM respectively, and demonstrates anticancer effects (WO2018019252A1; compound 11) [1].Formule :C23H24ClN7O3Couleur et forme :SolidMasse moléculaire :481.93DHODH-IN-12
CAS :DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.Formule :C10H9N3O2Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :203.2Ref: TM-T11021
1mg73,00€1mL*10mM (DMSO)122,00€5mg149,00€10mg213,00€25mg319,00€50mg447,00€100mg610,00€200mg823,00€CGP 53353
CAS :CGP 53353 (DAPH-7) is a PKC inhibitor with inhibitory effects on PKCβII and PKCβI and can be used to study atherosclerosis.Formule :C20H13F2N3O2Degré de pureté :98.11%Couleur et forme :SolidMasse moléculaire :365.33P18IN003
CAS :P18IN003 is a selective and effective p18(INK4C) inhibitor that inhibits the activity of p18 protein and can be used to study in vitro expansion ofFormule :C17H16N2O3Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :296.32JFN05510
CAS :Compound: 3'-O-tert-BDMS-5'-O-DMT-N2-IBG 2'-CE phosphoramidite; has anticancer properties and activates enzymes.Formule :C50H68N7O9PSiCouleur et forme :SolidMasse moléculaire :970.18Zelpolib
CAS :Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), inhibiting DNA replication. antiproliferative.Formule :C22H21N3O5S2Degré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :471.55Fosteabine
CAS :Fosteabine is an oral and prodrug analog of cytarabine. It is resistant to deoxycytidine deaminase.Formule :C27H50N3O8PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :575.67Aurora Kinases-IN-2
CAS :Aurora Kinases-IN-2 (12Aj) hinders Aurora A/B kinases (IC50: 90/152 nM), used in cancer studies.Formule :C22H18ClN5O3Couleur et forme :SolidMasse moléculaire :435.86LSN 3213128
CAS :LSN 3213128: a potent oral antifolate targeting AICARFT with IC50s of 16 nM (enzyme) and 19 nM (cells), offers anti-tumor effects.Formule :C17H16FN3O4S2Couleur et forme :SolidMasse moléculaire :409.45Myt1-IN-1
CAS :Myt1-IN-1 has anticancer effects that is a potent inhibitor of Myt1 with an IC 50 of <10 nM [1].Formule :C16H15ClN4O2Couleur et forme :SolidMasse moléculaire :330.77Atuveciclib S-Enantiomer
CAS :Atuveciclib S-Enantiomer is a (S)-form of BAY-1143572; a potent, selective CDK9 inhibitor with an IC50 of 16 nM.Formule :C18H18FN5O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.43DHODH-IN-24
CAS :DHODH-IN-24 (compound 16) serves as a powerful inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 91 nM [1].Formule :C26H26N4Couleur et forme :SolidMasse moléculaire :394.51AZD7762 HCl
CAS :AZD7762 HCl is a checkpoint kinase inhibitor, driving checkpoint abrogation and enhancing DNA-targeted treatment.Formule :C17H20ClFN4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :398.88VPC-70619
CAS :VPC-70619: Oral, selective N-Myc inhibitor; blocks cancer growth by hindering N-Myc-Max/DNA binding; well-absorbed.Formule :C16H8ClF3N4OCouleur et forme :SolidMasse moléculaire :364.71CID 5951923
CAS :CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.Formule :C16H18N2O7SDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :382.39Eg5 Inhibitor V, trans-24
CAS :Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.Formule :C26H21N3O3Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :423.46Ref: TM-T11155
1mg96,00€5mg193,00€1mL*10mM (DMSO)215,00€10mg289,00€25mg469,00€50mg642,00€100mg858,00€200mg1.153,00€BAY-958
CAS :BAY-958 is a potent and selective inhibitor of PTEFb/CDK9.Formule :C17H16FN5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :389.4AS-136A
CAS :AS-136A is an orally active MV RdRp inhibitor with antiviral activity that inhibits measles virus and blocks viral RNA synthesis.Formule :C17H19F3N4O3SDegré de pureté :98.52%Couleur et forme :SolidMasse moléculaire :416.42Ref: TM-T62160
1mg215,00€5mg537,00€1mL*10mM (DMSO)590,00€10mg802,00€25mg1.369,00€50mg1.783,00€100mg2.395,00€CDK5 inhibitor 20-223
CAS :CDK5 inhibitor 20-223 is a potent CDK2/CDK5 inhibitor,anti-Colorectal Cancer (CRC), inhibiting cell migration and inducing cell cycle arrest.Formule :C19H19N3OCouleur et forme :SolidMasse moléculaire :305.37Pyrazofurin
CAS :Pyrazofurin, a pyrimidine analogue, blocks cell growth and DNA synthesis by targeting UMP synthase & orotate-phosphoribosyltransferase (IC50: 0.06-0.37 μM).Formule :C9H13N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :259.22IPR-803
CAS :IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity.Formule :C27H23N3O4Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :453.492-Keto-D-galactose
CAS :2-Keto-D-galactose inhibits DNA synthesis and inhibits the proliferation of in vitro grown Ehrlich ascites tumor cells.Formule :C6H10O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :178.14CAP-53194
CAS :CAP-53194 is a selective Plk1 inhibitor.Formule :C21H14N6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.37GSK-3008348
CAS :GSK-3008348 is an antagonist of integrin alpha(v)beta6.Formule :C29H37N5O2Degré de pureté :99.547%Couleur et forme :SolidMasse moléculaire :487.64Mivobulin Isethionate
CAS :Mivobulin, a tubulin inhibitor (CI-980), may treat glioma, melanoma, prostate, and ovarian cancer, targeting colchicine-binding site.Formule :C19H25N5O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :451.5CFI-400437
CAS :CFI-400437 is an ATP-competitive PLK4 inhibitor (IC50: 0.6 nM) and is an indolequinone derivative.Formule :C29H28N6O2Couleur et forme :SolidMasse moléculaire :492.57Picoplatin
CAS :Picoplatin, an anti-cancer agent overcoming platinum resistance, alkylates DNA to block replication, transcription, and induce apoptosis.Formule :C6H10Cl2N2PtDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :376.14HHL-6
CAS :HHL-6 is a c-Fos and BDNF protein expression modulator.Formule :C19H26N2O3Couleur et forme :SolidMasse moléculaire :330.42Metralindole HCl
CAS :Metralindole is a reversible monoamine oxidase A (RIMA) inhibitor, it was investigated as a potential antidepressant.Formule :C15H18ClN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :291.78
