
Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(115 produits)
- CDK(547 produits)
- Arrêt du cycle cellulaire(5 produits)
- Chk(48 produits)
- DYRK(46 produits)
- Dynamine(27 produits)
- Ferroptose(227 produits)
- HSP(180 produits)
- Intégrine(270 produits)
- Kinésine(87 produits)
- LIM Kinase(21 produits)
- Microtubules associés(273 produits)
- PKC(127 produits)
- PLK(25 produits)
- ROCK(61 produits)
- Rho(6 produits)
- Wee1(14 produits)
- c-Myc(76 produits)
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3914 produits trouvés pour "Cycle cellulaire/point de contrôle"
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Syntelin
CAS :Syntelin: a selective CENP-E inhibitor with an IC50 of 160 nM; distinct from GSK923295, effective on resistant mutants.Formule :C21H20N6O2S3Couleur et forme :SolidMasse moléculaire :484.62Pyrazofurin
CAS :Pyrazofurin, a pyrimidine analogue, blocks cell growth and DNA synthesis by targeting UMP synthase & orotate-phosphoribosyltransferase (IC50: 0.06-0.37 μM).Formule :C9H13N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :259.22Zalunfiban
CAS :RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.Formule :C16H18N8O2SCouleur et forme :SolidMasse moléculaire :386.43IPR-803
CAS :IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity.Formule :C27H23N3O4Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :453.49MDK6204
CAS :MDK6204 is a selective inhibitor of CLK1 and CLK2.Formule :C20H20N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :360.41Cylindrospermopsin
CAS :Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.Formule :C15H21N5O7SCouleur et forme :SolidMasse moléculaire :415.42DNA Gyrase-IN-2
CAS :DNA Gyrase-IN-2 inhibits E. coli (IC50: 3.29-10.49 μM) and M. tuberculosis (IC50: 4.41-5.61 μM) COX, has antibacterial properties.Formule :C24H24N8OS2Couleur et forme :SolidMasse moléculaire :504.63CP681301
CAS :CP681301 is a potent CDK5 inhibitor with anti-tumor effects in Drosophila and reduces Glioma stem cells' growth and renewal.Formule :C17H22N4OCouleur et forme :SolidMasse moléculaire :298.38GR 144053 trihydrochloride
CAS :platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonistFormule :C18H30Cl3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :454.82Cdc7-IN-15
CAS :Cdc7-IN-15 (Example 108) is an inhibitor of cdc7 kinase that has potential to be used for cancer research [1].Formule :C12H14N4OSCouleur et forme :SolidMasse moléculaire :262.33UR-2922
CAS :UR-2922: Oral GPIIb/IIIa blocker with <1 nM affinity, slow 90 min k(off), no LIBS or prothrombotic effects.Formule :C25H25N7O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :519.51SAR156497
CAS :SAR156497: selective Aurora A/B/C inhibitor; IC50: 0.5 nM (A), 1 nM (B), 3 nM (C); good metabolic stability; anti-tumoral without genetic specificity.Formule :C27H24N4O4Couleur et forme :SolidMasse moléculaire :468.5CFI-400437
CAS :CFI-400437 is an ATP-competitive PLK4 inhibitor (IC50: 0.6 nM) and is an indolequinone derivative.Formule :C29H28N6O2Couleur et forme :SolidMasse moléculaire :492.57MLAF50
CAS :MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.Formule :C15H12I2O4Couleur et forme :SolidMasse moléculaire :510.06GSK3182571
CAS :GSK3182571 is a non-speci c kinase inhibitor[1].Formule :C25H31ClN8OCouleur et forme :SolidMasse moléculaire :495.02Cdc7-IN-9
CAS :Cdc7-IN-9 can be used for the research of cancer which is a potent inhibitor of Cdc7 [1].Formule :C15H17N5OSCouleur et forme :SolidMasse moléculaire :315.39Binucleine 2
CAS :Binucleine 2: Drosophila Aurora B kinase inhibitor (Ki=0.36μM), dose-dependent, minimal effect on human/X. laevis kinases, disrupts mitosis in fly cells.Formule :C13H11ClFN5Couleur et forme :SolidMasse moléculaire :291.71HBV-IN-4
CAS :HBV-IN-4, a phthalazinone, inhibits HBV DNA replication orally (IC50: 14 nM), encouraging genome-free capsids with strong anti-HBV effects.Formule :C24H19ClFN5O3Couleur et forme :SolidMasse moléculaire :479.89IRE1α kinase-IN-7
CAS :IRE1α kinase-IN-7 is a chemical compound functioning as an inhibitor of IRE1α kinase, primarily utilized in the research of diseases related to endoplasmicFormule :C28H25F3N6OCouleur et forme :SolidMasse moléculaire :518.53SR7826
CAS :SR7826 is a selective LIMK inhibitor.Formule :C22H21N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.43WF-536 Hydrochloride
CAS :WF-536 Hydrochloride, a novel inhibitor of ROCK, inhibits tumour metastasis in some animal models.Formule :C14H16ClN3OCouleur et forme :SolidMasse moléculaire :277.75BA-1049
CAS :BA-1049 is a selective ROCK2 inhibitor.Formule :C16H21N3O2SCouleur et forme :SolidMasse moléculaire :319.42XIE18-6
CAS :XIE18-6 is a novel INK4C inhibitor that blocks p18 activity and promotes ex vivo expansion of human and murine hematopoietic stem cells.Formule :C18H15NO6SDegré de pureté :99.712%Couleur et forme :SolidMasse moléculaire :373.38HOI-07
CAS :HOI-07 is a specific Aurora B inhibitor.Formule :C19H13NO4Couleur et forme :SolidMasse moléculaire :319.31CI-898 HCl
CAS :CI-898 HCl: lipophilic antifolate, DHFR inhibitor, effective on methotrexate-resistant cancers, synergizes with other drugs in advanced P338 leukemia.Formule :C19H26Cl3N5O3Couleur et forme :SolidMasse moléculaire :478.8XVA143
CAS :XVA143 is an integrin α/β I-like allosteric antagonist, inhibits LFA-1 (αLβ2 integrin)-dependent firm adhesion, induces extended conformations of integrins.Formule :C25H21Cl2N3O8Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :562.36CDK4/6-IN-14
CAS :CDK4/6-IN-14: potent CDK4/6 inhibitor, IC50s 10/16 nM, >60-fold selectivity over CDKs 1/2/7/9, selective across 205 kinases.Formule :C24H27ClFN7OCouleur et forme :SolidMasse moléculaire :483.97CDK8-IN-7
CAS :CDK8-IN-7 is a potent CDK8 inhibitor with a Kd of 3.5 nM, showing promise for AML research.Formule :C30H40N2Couleur et forme :SolidMasse moléculaire :428.653'-Deoxyuridine-5'-triphosphate
CAS :3'-dUTP, a nucleotide analogue, competitively inhibits RNA polymerases I & II, with a Ki of 2.0 µM.Formule :C9H15N2O14P3Couleur et forme :SolidMasse moléculaire :468.14Trimetrexate glucuronate
CAS :Trimetrexate glucuronate, a folic acid foe, blocks DNA/RNA synthesis by inhibiting purine and thymidylic acid production, may fight tumors.Formule :C25H33N5O10Couleur et forme :SolidMasse moléculaire :563.564Chlorozotocin
CAS :Chlorozotocin is a nitrosourea. It is used for cancer therapy.Formule :C9H16ClN3O7Couleur et forme :SolidMasse moléculaire :313.69IS-741 calcium
CAS :IS-741 calcium is a phospholipase A2 inhibitor.Formule :C30H38CaF6N6O6S2Couleur et forme :SolidMasse moléculaire :796.86CFI-400936
CAS :CFI-400936: potent TTK inhibitor (IC50=3.6nM), potential anticancer, active in cell assays, selective vs. human kinases.Formule :C25H27N5O3SCouleur et forme :SolidMasse moléculaire :477.58OM-137
CAS :OM137 inhibits Aurora kinases, impedes cell growth at high doses, and enhances low-dose paclitaxel effects.Formule :C13H14N4O3SCouleur et forme :SolidMasse moléculaire :306.34IS-741 potassium
CAS :IS-741 potassium is a phospholipase A2 inhibitor.Formule :C15H19F3KN3O3SCouleur et forme :SolidMasse moléculaire :417.49Teloxantrone
CAS :Teloxantrone: an anthrapyrazole antibiotic inhibiting DNA replication, RNA/protein synthesis by interacting with DNA and topoisomerase II.Formule :C21H25N5O4Couleur et forme :SolidMasse moléculaire :411.45Tripolin A
CAS :Tripolin A is a specific non-ATP competitive inhibitor of Aurora A kinase(Aurora A and Aurora B with IC50 values of 1.5 μM and 7 μM, respectively)Formule :C15H11NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :253.25CDK5 inhibitor 20-223
CAS :CDK5 inhibitor 20-223 is a potent CDK2/CDK5 inhibitor,anti-Colorectal Cancer (CRC), inhibiting cell migration and inducing cell cycle arrest.Formule :C19H19N3OCouleur et forme :SolidMasse moléculaire :305.37TCS 2314
CAS :TCS 2314, Selective VLA-4 antagonist (IC50=4.4 nM), high clearance/low oral bioavailability, for asthma research.Formule :C28H34N4O6Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :522.5910-Deazaaminopterin
CAS :10-Deazaaminopterin is a poly-gamma-glutamyl metabolite of the experimental anticancer drug, a folic acid antagonist, antineoplastic agent enzyme inhibitor.Formule :C20H21N7O5Couleur et forme :SolidMasse moléculaire :439.42ROCK-IN-4
CAS :ROCK-IN-4: Inhibits ROCK, sustains NO release, disrupts F-actin, hinders HTM cell respiration, aids glaucoma research.Formule :C20H26ClFN4O7SCouleur et forme :SolidMasse moléculaire :520.96USP28-IN-2
CAS :USP28-IN-2 selectively inhibits USP28 (IC50=0.3 μM), degrades c-Myc, kills cancer cells, lowers ankyrin-1/2, and enhances Regorafenib effects.Formule :C23H20Cl2N2O3SCouleur et forme :SolidMasse moléculaire :475.39JH-XIV-68-3
CAS :JH-XIV-68-3: Selective DYRK1A/B inhibitor; effective in HNSCC cell lines.Formule :C21H17F3N8OCouleur et forme :SolidMasse moléculaire :454.415-OHdU
CAS :5-OHdU (5-OHdU) is a major oxidation product of 2'-Deoxycytidine and can be incorporated into DNA in vitro.Formule :C9H12N2O6Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :244.2Ref: TM-T19152
1mg35,00€5mg75,00€1mL*10mM (DMSO)84,00€10mg105,00€25mg192,00€50mg289,00€100mg409,00€200mg590,00€Cdc7-IN-14
CAS :Cdc7-IN-14 (compound 82) is a potent CDC7 inhibitor with an IC50 < 1 nM, promising for cancer research.Formule :C18H20N4O2SCouleur et forme :SolidMasse moléculaire :356.44Akt1&PKA-IN-2
CAS :Akt1&PKA-IN-2 ((R)-29) inhibits AKT1, PKAα, CDK2 with IC50s: 0.007, 0.01, 0.69 µM respectively.Formule :C20H17Cl2N3OCouleur et forme :SolidMasse moléculaire :386.27CDK1-IN-1
CAS :CDK1-IN-7 inhibits CDK1 at 161.2 nM, triggers p53-dependent apoptosis, and selectively targets tumor growth.Formule :C27H23N5O3Couleur et forme :SolidMasse moléculaire :465.5Cdc7-IN-4
CAS :Cdc7-IN-4 is a potent inhibitor of Cdc7 kinase.Formule :C22H24F3N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :479.45Valategrast
CAS :Valategrast: potent, oral dual α4β1/α4β7 integrin antagonist, may treat COPD and asthma.Formule :C30H32Cl3N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :604.95CB 3731
CAS :CB 3731 is used in fluorine-19 nuclear magnetic resonance studies of binary and ternary complexes of thymidylate synthase.Formule :C23H24FN5O6Couleur et forme :SolidMasse moléculaire :485.46AG-012986
CAS :AG-012986: a selective CDK inhibitor with in vitro and in vivo antitumor effects; low IC50 in 14/18 cancer cell types; CAS# 486414-35-1.Formule :C22H23F2N5O2SCouleur et forme :SolidMasse moléculaire :459.51FLDP-5
CAS :FLDP-5: BBB-penetrant curcuminoid, induces ROS, DNA damage, S phase arrest, suppresses tumors in LN-18 cells.Formule :C21H21NO5Couleur et forme :SolidMasse moléculaire :367.4CDK7-IN-2
CAS :CDK7-IN-2 inhibits CDK7, essential for RNA polymerase II activation and cell cycle control, with cancer research potential.Formule :C26H39N7O3Couleur et forme :SolidMasse moléculaire :497.63Cdc7-IN-17
CAS :Cdc7-IN-17 is a potent inhibitor of CDC7 with an IC 50 of <10 μM that can be used in cancer research [1].Formule :C13H15N5OSCouleur et forme :SolidMasse moléculaire :289.36AM-5308
CAS :AM-5308 is a kinesin KIF18A inhibitor that can be used to study cancer.Formule :C26H35N5O5SDegré de pureté :98.06% - 99.58%Couleur et forme :SolidMasse moléculaire :529.65CB10-277
CAS :CB10-277 is a synthetic anti-cancer drug related to dacarbazine that alkylates DNA, inhibits DNA replication and repair, and may block DNA synthesis.Formule :C9H11N3O2Couleur et forme :SolidMasse moléculaire :193.2Edatrexate
CAS :Edatrexate (CGP 30694), a Methotrexate analog, combats MTX-resistant tumors and researches various cancers.Formule :C22H25N7O5Couleur et forme :SolidMasse moléculaire :467.48Crisnatol
CAS :Crisnatol (BWA770U) is an oral anticancer DNA intercalator, toxic to breast cancer cells, not skin fibroblasts.Formule :C23H23NO2Couleur et forme :SolidMasse moléculaire :345.43EMD534085
CAS :EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).Formule :C25H31F3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :476.53AP-1/NF-κB activation inhibitor 1
CAS :AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation ( IC 50 =1 μM), does not blocking basalFormule :C13H11F3N4O4Degré de pureté :99.52% - 99.91%Couleur et forme :SolidMasse moléculaire :344.25Ref: TM-T9656
1mg70,00€2mg90,00€5mg152,00€1mL*10mM (DMSO)166,00€10mg205,00€25mg334,00€50mg497,00€100mg692,00€500mg1.404,00€HBV-IN-21
CAS :HBV-IN-21 inhibits HBV DNA replication (IC50: 2.2 μM) and binds HBV capsid protein well (KD: 60.0 μM).Formule :C17H17FN4OS2Couleur et forme :SolidMasse moléculaire :376.47SR31527
CAS :SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.Formule :C15H14ClN3OSDegré de pureté :98.52%Couleur et forme :SolidMasse moléculaire :319.81Ref: TM-T28848
1mg63,00€5mg137,00€1mL*10mM (DMSO)145,00€10mg215,00€25mg439,00€50mg708,00€100mg1.144,00€SP-471P
CAS :SP-471P inhibits DENV protease; EC50: DENV1-5.9 μM, DENV2-1.4 μM, DENV3-5.1 μM, DENV4-1.7 μM; CC50 >100 μM; lowers viral RNA synthesis.Formule :C33H26BrN5O2Couleur et forme :SolidMasse moléculaire :604.5XMD-17-51
CAS :XMD-17-51 has DCLK1 kinase inhibitory activity, inhibits DCLK1 and cell proliferation, and can be used in lung cancer research.Formule :C21H24N8ODegré de pureté :99.04%Couleur et forme :SoildMasse moléculaire :404.47CDK4/6-IN-7
CAS :CDK4/6-IN-7 is an oral, potent CDK4/6 inhibitor with IC50s of 1.58/4.09 nM, crucial for breast cancer studies.Formule :C18H18ClN5O3Couleur et forme :SolidMasse moléculaire :387.82Aloisine B
CAS :Aloisine B (AloisineB) inhibited cyclin-dependent kinase and glycogen synthase kinase with IC50 values of 0.85 µM and 0.75 µM, respectively.Formule :C15H14ClN3Degré de pureté :95.15%Couleur et forme :SolidMasse moléculaire :271.74CAY10760
CAS :CAY10760 inhibits RAD51-BRCA2 interaction (EC50=19 μM), reduces homologous recombination by 54%, and hinders BxPC-3/Capan-1 cancer cell proliferation.Formule :C28H24ClN3O3Couleur et forme :SolidMasse moléculaire :485.96DHODH-IN-19
CAS :DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)Formule :C22H18ClF6N3O3Couleur et forme :SolidMasse moléculaire :521.84BMS-986463
CAS :BMS-986463 is a WEE1 kinase molecule gel degrader and a CRBN E3 ligase regulator (CELMoD). BMS-986463 significantly inhibits tumor regression and reduces the level of phosphorylated CDK2. BMS-986463 can be used in the research of advanced malignant solid tumors such as non-small cell lung cancer (NSCLC).Formule :C32H33FN4O5Couleur et forme :SolidMasse moléculaire :572.63M443
CAS :M443 is a potent small molecule inhibitor of MRK that inhibits radiation-induced activation of p38 and Chk2 and can be used in cancer research.Formule :C31H30F3N7O2Degré de pureté :98.95%Couleur et forme :SolidMasse moléculaire :589.612-Fluoroadenine
CAS :2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.
Formule :C5H4FN5Degré de pureté :98.84% - 99.62%Couleur et forme :White To Light Yellow Crystal PowderMasse moléculaire :153.12TH470
CAS :TH470, a potent and highly selective inhibitor of LIM kinase 1/2 (LIMK1/2), demonstrates specificity with IC50 values of 9.8 nM for LIMK1 and 13 nM for LIMK2,Formule :C30H31N5O5S2Couleur et forme :SolidMasse moléculaire :605.73cp028
CAS :cp028 inhibits pre-mRNA splicing in vitro.Formule :C23H17FN2O4Couleur et forme :SolidMasse moléculaire :404.39Aurora kinase inhibitor-10
CAS :Aurora kinase inhibitor-10 is an orally active Aurora B inhibitor (IC50: 8 nM) that exhibits antitumour effects.Formule :C21H19F5N6O4SCouleur et forme :SolidMasse moléculaire :546.47Dyrk1A-IN-5
CAS :Potent DYRK1A inhibitor with IC50s: 6 nM overall, 0.5 μM SF3B1, 2.1 μM tau phosphorylation. Useful for Down syndrome studies.Formule :C16H9IN2O2Couleur et forme :SolidMasse moléculaire :388.16Crozbaciclib fumarate
CAS :Crozbaciclib fumarate is a CDK4/6 inhibitor with IC 50 s of 3 and 1 nM, respectively.Formule :C32H34F2N6O4Couleur et forme :SolidMasse moléculaire :604.65CRT-0105446
CAS :CRT-0105446 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.Formule :C20H18F3N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.44Akt1&PKA-IN-1
CAS :Akt1&PKA-IN-1 inhibits Akt/PKA: IC50 = 0.03μM (PKAa), 0.11μM (Akt), 9.8μM (CDK2); selective for CDK2.Formule :C20H17Cl2N3OCouleur et forme :SolidMasse moléculaire :386.27Aurora Kinases-IN-3
CAS :Aurora Kinases-IN-3 is an oral AURKB inhibitor that disrupts its mitotic localization, not its H3 Ser10 phosphorylation.Formule :C20H16F3N3O4Couleur et forme :SolidMasse moléculaire :419.35SRPIN-803
CAS :SRPIN-803 is a selective dual SRPK1 and CK2 inhibitor.Formule :C14H9F3N4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :370.31GSK317354A
CAS :GSK317354A is a GRK2 inhibitor.Formule :C25H18F4N6OCouleur et forme :SolidMasse moléculaire :494.44BOP sodium
CAS :BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.Formule :C25H29N3NaO7SCouleur et forme :SolidMasse moléculaire :538.57RSK-IN-1
CAS :RSK-IN-1 (compound 7d) shows anti-tumor activity. RSK-IN-1 is an inhibitor of RSK that inhibits the phosphorylation of YB-1 [1].Formule :C22H17NO2Couleur et forme :SolidMasse moléculaire :327.38DNA Gyrase-IN-4
CAS :DNA Gyrase-IN-4 inhibits DNA cyclooxygenase (IC50: 0.13 μM) and is effective against Salmonella and E. coli.Formule :C22H15Cl2NO4SCouleur et forme :SolidMasse moléculaire :460.33FUBP1-IN-2
CAS :FUBP1-IN-2 hinders FUBP1, affects c-Myc and p21 expression, and depletes polyamines.Formule :C26H26ClN3O4Couleur et forme :SolidMasse moléculaire :479.965,10-Dideazaaminopterin
CAS :5,10-Dideazaaminopterin is an antileukemic drug.Formule :C21H22N6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.44HBV-IN-14
CAS :HBV-IN-14: a pyridinopyrimidinone, potent cccDNA inhibitor for HBV study (patent WO2021190502A1, comp 5).Formule :C22H21ClN2O5Couleur et forme :SolidMasse moléculaire :428.87Poloxipan
CAS :Poloxipan inhibits PLK1 (IC50: 3.2µM), PLK2 (1.7µM), PLK3 (3µM); minimal effect on Chk2, STAT1, STAT5b, Lck.Formule :C14H10BrN3O3SCouleur et forme :SolidMasse moléculaire :380.225-Ethynyluridine
CAS :5-Ethynyluridine marks new RNA for RICK, capturing proteins on various RNAs, even nonpolyadenylated types.Formule :C11H12N2O6Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :268.22Ref: TM-T36971
5mg49,00€1mL*10mM (DMSO)54,00€10mg84,00€25mg138,00€50mg236,00€100mg344,00€200mg515,00€DHODH-IN-4
CAS :DHODH-IN-4 inhibits human & Plasmodium DHODH; IC50: 4 μM (Pf), 0.18 μM (Hs). It has antimalarial properties.Formule :C17H12Cl2N2O2Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :347.2Ref: TM-T11027
1mg109,00€2mg163,00€5mg243,00€1mL*10mM (DMSO)248,00€10mg355,00€25mg532,00€50mg750,00€100mg1.009,00€500mg2.035,00€JA2131
CAS :JA2131: Small PARG inhibitor, IC50 0.4μM, induces DNA damage, stalls replication, kills cancer cells.Formule :C13H19N5O2S2Couleur et forme :SolidMasse moléculaire :341.45SPC-839
CAS :SPC-839 is an IKK-2 Inhibitor with oral activity.Formule :C18H14N4O3SCouleur et forme :SolidMasse moléculaire :366.39ARN22089
CAS :ARN22089 is an oral active CDC42 GTPase interaction inhibitor that blocks tumour growth in BRAF mutant mouse melanoma models and PDXs in vivo.Formule :C23H27N5Degré de pureté :98.37%Couleur et forme :SolidMasse moléculaire :373.49Ref: TM-T85727
1mg109,00€5mg260,00€1mL*10mM (DMSO)286,00€10mg385,00€25mg647,00€50mg964,00€100mg1.431,00€200mg1.963,00€SB-772077B dihydrochloride
CAS :SB-772077B dihydrochloride is an aminofurazan-based Rho kinase inhibitor (IC50s: 5.6 nM and 6 nM toward ROCK1 and ROCK2, respectively).Formule :C15H20Cl2N8O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :415.28MTH1-IN-2
CAS :MTH1-IN-2 is an inhibitor of MutT homolog 1 (MTH1), with anti-tumor activity.Formule :C24H27N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :469.55IXA6
CAS :IXA6 is an IRE1/XBP1s agonist with potential vasoprotective activity for the study of neurodegenerative diseases such as Parkinson's disease.Formule :C22H20ClN3O3SDegré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :441.93H-1152
CAS :H-1152 is a potent, specific, ATP-competitive, and cell permeable ROCK inhibitor (Ki = 1.6 nM).Formule :C16H21N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.42MMV688845
CAS :MMV688845: NTM RNA polymerase inhibitor, kills Mycobacterium abscessus, and fights TB.Formule :C24H25N3O3SCouleur et forme :SolidMasse moléculaire :435.54Antibacterial agent 124
CAS :Antibacterial agent 124 inhibits Sa ProRS with an IC50 of 0.18 μM.Formule :C16H17ClFN3O2Couleur et forme :SolidMasse moléculaire :337.78Rho-Kinase-IN-2
CAS :Rho-Kinase-IN-2, an oral ROCK inhibitor (IC50=3nM), penetrates the CNS; potential in Huntington's research.Formule :C20H25FN4O2Couleur et forme :SolidMasse moléculaire :372.44

