
Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(115 produits)
- CDK(546 produits)
- Arrêt du cycle cellulaire(5 produits)
- Chk(48 produits)
- DYRK(47 produits)
- Dynamine(27 produits)
- Ferroptose(227 produits)
- HSP(180 produits)
- Intégrine(269 produits)
- Kinésine(87 produits)
- LIM Kinase(20 produits)
- Microtubules associés(274 produits)
- PKC(126 produits)
- PLK(25 produits)
- ROCK(62 produits)
- Rho(6 produits)
- Wee1(14 produits)
- c-Myc(76 produits)
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3906 produits trouvés pour "Cycle cellulaire/point de contrôle"
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10-Formylfolic acid
CAS :10-Formylfolic acid is a novel and potent inhibitor of dihydrofolate reductase, which can be used in leukemia research.Formule :C20H19N7O7Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :469.41AGX51
CAS :AGX51 is an antagonist of inhibitor of DNA binding (ID) proteins. AGX51 treatment lead to pan-Id degradation, cell cycle arrest, and cell death.Formule :C27H29NO4Degré de pureté :97.65%Couleur et forme :OilMasse moléculaire :431.52Ref: TM-T10268
1mg96,00€5mg205,00€10mg334,00€25mg652,00€50mg858,00€100mg1.108,00€200mg1.504,00€1mL*10mM (DMSO)227,00€NSC16168
CAS :NSC16168 is a selective ERCC1-XPF inhibitor that inhibits DNA repair and potentiates the antitumor activity of cisplatin.Formule :C17H15NO9S3Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :473.5Ref: TM-T16351
1mg60,00€5mg130,00€10mg200,00€25mg338,00€50mg497,00€100mg708,00€200mg964,00€1mL*10mM (DMSO)135,00€L82
CAS :L82: A selective, non-competitive DNA Lig1 inhibitor with anti-proliferative effects on breast cancer cells. IC50=12 μM.Formule :C11H8ClN5O4Degré de pureté :98.06% - 98.91%Couleur et forme :SolidMasse moléculaire :309.67Ref: TM-T60753
5mg70,00€10mg103,00€25mg187,00€50mg298,00€100mg472,00€500mg1.026,00€1mL*10mM (DMSO)77,00€Cdc7-IN-7c
CAS :Cdc7-IN-7c (Cdc7 inhibitor-7c) has antitumor activity and has inhibitory effect on liver cancer, lung cancer, kidney cancer, brain cancer and cervical cancer.Formule :C15H17N5OSDegré de pureté :98.19% - 99.22%Couleur et forme :SolidMasse moléculaire :315.39Ref: TM-T23867
1mg315,00€5mg745,00€10mg1.018,00€25mg1.431,00€50mg1.783,00€100mg2.250,00€500mg4.410,00€1mL*10mM (DMSO)600,00€Galocitabine
CAS :Galocitabine (Neofrutulon), a thymidylate synthase inhibitor, is used potentially for the treatment of cancer.Formule :C19H22FN3O8Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :439.39CF-1743
CAS :CF-1743 is an anti-varicella zoster virus nucleoside and inhibits VZV replication.
Formule :C22H26N2O5Degré de pureté :99.6% - 99.79%Couleur et forme :SolidMasse moléculaire :398.45GKI-1
CAS :GKI-1, a GWL kinase inhibitor: IC50 - 4.9 µM for hGWLFL, 2.5 µM for hGWL-KinDom, 11 µM for ROCK1; weak on PKA.Formule :C15H12ClN3Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :269.73Ref: TM-T11402
1mg93,00€5mg200,00€10mg299,00€25mg485,00€50mg658,00€100mg892,00€1mL*10mM (DMSO)215,00€PS423
CAS :PS423 is a substrate-selective protein kinase PDK1 inhibitor that acts by binding to the PIF-pocket allosteric docking site.Formule :C25H23F3O9Degré de pureté :98.81% - 99.26%Couleur et forme :SolidMasse moléculaire :524.44NR2F6 modulator-1
CAS :NR2F6 modulator-1, a potent agent for NR2F6, affects immune response and tumor stem cell activity.Formule :C23H17NO5SDegré de pureté :98.31%Couleur et forme :SolidMasse moléculaire :419.45Ref: TM-T62204
1mg87,00€5mg178,00€10mg268,00€25mg502,00€50mg703,00€100mg982,00€1mL*10mM (DMSO)203,00€CHD1Li 6.11
CAS :CHD1Li 6.11 inhibits CHD1L protein (IC50: 3.3 µM), shrinks CRC tumors in vivo, and is orally active.Formule :C21H22BrN5OSDegré de pureté :99.04%Couleur et forme :SolidMasse moléculaire :472.4Ref: TM-T63049
1mg92,00€5mg216,00€10mg354,00€25mg597,00€50mg852,00€100mg1.159,00€500mg2.327,00€1mL*10mM (DMSO)227,00€Chiauranib
CAS :Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.Formule :C27H21N3O3Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :435.47Ref: TM-T35570
1mg66,00€5mg144,00€10mg245,00€25mg492,00€50mg710,00€100mg973,00€1mL*10mM (DMSO)157,00€Peldesine
CAS :Peldesine (BCX 34), an oral purine nucleoside phosphorylase blocker, halts T-cell growth; used in CTCL, psoriasis, HIV research. IC50: 800 nM.Formule :C12H11N5ODegré de pureté :99.27% - 99.9%Couleur et forme :SolidMasse moléculaire :241.25Ref: TM-T12399
1mg108,00€5mg260,00€10mg416,00€25mg690,00€50mg964,00€100mg1.305,00€500mg2.592,00€1mL*10mM (DMSO)286,00€SB 328437
CAS :SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).Formule :C21H18N2O5Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :378.38Ref: TM-T23321
1mg39,00€5mg82,00€10mg123,00€25mg250,00€50mg394,00€100mg618,00€200mg874,00€1mL*10mM (DMSO)69,00€GS-6620 PM
CAS :GS-6620 PM, oral Hep C polymerase inhibitor prodrug, is a potent GS-6620 derivative with limited activity against other viruses.Formule :C13H15N5O4Degré de pureté :98.52% - 98.7%Couleur et forme :SolidMasse moléculaire :305.29Ryuvidine
CAS :Ryuvidine is a dual inhibitor of KDM5A and SETD8, an inducer of the DNA damage response, and can be used to study breast cancer and erythroderma.Formule :C15H12N2O2SDegré de pureté :98.6%Couleur et forme :SolidMasse moléculaire :284.336-Hydroxy-DOPA
CAS :6-Hydroxy-DOPA is an allosteric inhibitor of RAD52, it inhibits proliferation of BRCA-deficient cancer cells in vitro and also inhibits APE1.
Formule :C9H11NO5Degré de pureté :97.78% - 97.95%Couleur et forme :SolidMasse moléculaire :213.19EHT 1610
CAS :EHT 1610 (EHT 5372) is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively.Formule :C18H14FN5O2SDegré de pureté :98.43%Couleur et forme :SolidMasse moléculaire :383.4CMX-521
CAS :CMX521: an antiviral for norovirus, effective against rotavirus; inhibits viral RNA polymerase.Formule :C13H17N5O5Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :323.3Antiviral agent 17
CAS :Antiviral agent 17, EC50 0.015 μM in human assay, effective against murine norovirus, may aid infectious/malignant disease research.Formule :C11H14N4O4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :266.25CQ211
CAS :CQ211 is a potent selective RIOK2 inhibitor, Kd 6.1 nM, effectively inhibits cancer cell line proliferation.Formule :C26H22F3N7O2Degré de pureté :97.01% - 98.31%Couleur et forme :SolidMasse moléculaire :521.49BML-259
CAS :BML-259 inhibits CDK5/CDK2 (IC50: 64/98 nM) for cancer and neurodegeneration research.Formule :C14H16N2OSDegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :260.35Ref: TM-T36964
5mg48,00€10mg80,00€25mg160,00€50mg264,00€100mg462,00€500mg982,00€1mL*10mM (DMSO)50,00€CHK1-IN-3
CAS :CHK1-IN-3 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 0.4 nM).Formule :C20H23N9ODegré de pureté :98.78%Couleur et forme :SolidMasse moléculaire :405.46Ref: TM-T10791
1mg168,00€2mg231,00€5mg371,00€10mg558,00€25mg868,00€50mg1.153,00€100mg1.575,00€200mg2.125,00€1mL*10mM (DMSO)423,00€CDK4/6/1 Inhibitor
CAS :CDK4/6/1 Inhibitor (Crozbaciclib) is a type of CDK4/6 inhibitor (IC50s: 3 and 1 nM).Formule :C28H30F2N6Degré de pureté :97.25% - 99.72%Couleur et forme :SolidMasse moléculaire :488.57AzddMeC
CAS :AzddMeC (Az-Dcme) is an HIV-1 reverse transcriptase and HIV-1 replication inhibitor with antiretroviral activity.AzddMeC is used in the study of HIV-1 infectionFormule :C10H14N6O3Degré de pureté :97.14% - 99.62%Couleur et forme :SolidMasse moléculaire :266.26CDK8-IN-1
CAS :CDK8-IN-1 is a selective CDK8 inhibitor (IC50: 3 nM).Formule :C11H8F3N3ODegré de pureté :98.48%Couleur et forme :SolidMasse moléculaire :255.2Ref: TM-T10740
1mg87,00€5mg216,00€10mg311,00€25mg525,00€50mg707,00€100mg944,00€1mL*10mM (DMSO)240,00€Firategrast
CAS :Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervousFormule :C27H27F2NO6Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :499.5Ref: TM-TQ0291
1mg44,00€5mg93,00€10mg133,00€25mg268,00€50mg439,00€100mg708,00€200mg964,00€1mL*10mM (DMSO)92,00€Talviraline
CAS :Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in aFormule :C15H20N2O3S2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :340.46BioE-1115
CAS :BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM).Formule :C19H18FN3O2Degré de pureté :97.54%Couleur et forme :SolidMasse moléculaire :339.36Cdk2 Inhibitor II
CAS :Cdk2 Inhibitor II is a selective and potent CDK2 inhibitor50 at 60 nM.Formule :C14H11BrN4O3SDegré de pureté :97.27%Couleur et forme :SolidMasse moléculaire :395.23Ref: TM-T36933
1mg98,00€2mg133,00€5mg192,00€10mg289,00€25mg485,00€50mg692,00€100mg945,00€500mg1.873,00€DIF-3
CAS :DIF-3 activates GSK-3β, degrades cyclin D1/c-Myc, and inhibits Wnt/β-catenin in DLD-1 cells, curbing HeLa cell proliferation.Formule :C13H17ClO4Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :272.72Ref: TM-T60485
1mg96,00€5mg222,00€10mg333,00€25mg557,00€50mg795,00€100mg1.071,00€500mg2.187,00€1mL*10mM (DMSO)205,00€D-I03
CAS :D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM.Formule :C23H36N6SDegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :428.64Ref: TM-T10936
1mg34,00€5mg73,00€10mg119,00€25mg236,00€50mg353,00€100mg517,00€200mg737,00€1mL*10mM (DMSO)80,00€RP-6306
CAS :Lunresertib (RP-6306) is a potent, selective, and orally active PKMYT1 inhibitor with an IC50 of 14 nM.Cost-effective and quality-assured.
Formule :C18H20N4O2Degré de pureté :98.41% - 99.28%Couleur et forme :SolidMasse moléculaire :324.38Eprociclovir
CAS :Eprociclovir (A-5021) is a novel acyclovir analog that is a potent inhibitor of EHV1 replication and may be used for the treatment and/or prevention ofFormule :C11H15N5O3Degré de pureté :98.50% - 99.86%Couleur et forme :SolidMasse moléculaire :265.27SEL120-34A
CAS :SEL120-34A inhibits CDK8 (IC50: 4.4 nM) & CDK19 (10.4 nM), less on CDK9 (1070 nM), has antitumor properties.Formule :C15H18Br2N4Degré de pureté :99.764% - 99.84%Couleur et forme :SolidMasse moléculaire :414.14Ref: TM-T10744
1mg612,00€5mg1.529,00€10mg1.880,00€25mg2.178,00€50mg2.862,00€100mg3.870,00€1mL*10mM (DMSO)1.835,00€ITX3
CAS :ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM.Formule :C22H17N3OSDegré de pureté :97.28%Couleur et forme :SolidMasse moléculaire :371.45hDHODH-IN-7
CAS :hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor.Formule :C21H23FN4ODegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :366.43Ref: TM-T11031
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€500mg2.147,00€1mL*10mM (DMSO)266,00€hSMG-1 inhibitor 11e
CAS :hSMG-1 inhibitor 11e is an effective and selective inhibitor of hSMG-1 (IC50 <0.05 nM) and can be used in studies about cancer treatment.Formule :C26H27N7O3SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :517.69-Isopropylolomoucine
CAS :9-Isopropylolomoucine (N9-Isopropylolomoucine), a cell cycle protein-dependent kinase inhibitor, is a thiopurine.Formule :C17H22N6ODegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :326.4Ref: TM-T23589
1mg315,00€5mg745,00€10mg1.018,00€25mg1.431,00€50mg1.783,00€100mg2.250,00€500mg4.410,00€1mL*10mM (DMSO)607,00€Caracemide
CAS :Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.Formule :C6H11N3O4Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :189.17SJ572403
CAS :SJ572403 inhibits p27 protein, Kd 2.2 mM at D2 subdomain of p27-KID; useful in disordered protein disease research.Formule :C13H17N5O2Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :275.31Ref: TM-T16889
1mg39,00€5mg86,00€10mg119,00€25mg231,00€50mg371,00€100mg537,00€200mg710,00€1mL*10mM (DMSO)95,00€Elarofiban
CAS :Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.Formule :C22H32N4O4Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :416.516RK73
CAS :6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 µM). 6RK73 shows almost no inhibition of UCHL3 (IC50: 236 µM).Formule :C13H17N5O2SDegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :307.37Ref: TM-T10188
1mg144,00€5mg298,00€10mg510,00€25mg825,00€50mg1.130,00€100mg1.510,00€500mg3.060,00€1mL*10mM (DMSO)328,00€OTUB1/USP8-IN-1
CAS :OTUB1/USP8-IN-1 is an OTUB1/USP8 inhibitor with anticancer activity for the study of non-small cell lung cancer.Formule :C22H16ClFN2O4Degré de pureté :98.59%Couleur et forme :SoildMasse moléculaire :426.83CDK-IN-2
CAS :CDK-IN-2 (CDK inhibitor II) is a potent and specific CDK9 inhibitor (IC50: <8 nM).Formule :C18H19ClFN3O2Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :363.81Ref: TM-TQ0078
1mg38,00€2mg51,00€5mg96,00€10mg138,00€25mg258,00€50mg376,00€100mg532,00€500mg1.063,00€1mL*10mM (DMSO)92,00€Rhodblock 6
CAS :Rhodblock 6 is a Rho kinase inhibitor, blocking phosphorylated MRLC localization by targeting ROCK activity.Formule :C12H13N3ODegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :215.25Anticancer agent 73
CAS :Anticancer agent 73 inhibits TRBP, disrupting TRBP-Dicer, and hinders HCC growth and spread by altering HCC miRNA and protein expression.Formule :C14H15NO4Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :261.27GSK2643943A
CAS :GSK2643943A is a deubiquitylating enzyme (DUB) inhibitor, with an IC 50 of 160 nM for USP20/Ub-Rho. GSK2643943A has anti-tumor efficacy.Formule :C17H12FN3Degré de pureté :97.09%Couleur et forme :SolidMasse moléculaire :277.3Ref: TM-T11485
1mg39,00€2mg50,00€5mg82,00€10mg120,00€25mg236,00€50mg356,00€100mg537,00€200mg762,00€1mL*10mM (DMSO)90,00€RP-6685
CAS :RP-6685 is a potent, selective DNA Polθ inhibitor with strong oral efficacy, an IC50 of 5.8 nM, and marked antitumor effects in mice.Formule :C22H14F7N5ODegré de pureté :99.65%Couleur et forme :SoildMasse moléculaire :497.37Ref: TM-T60187
1mg84,00€5mg152,00€10mg219,00€25mg358,00€50mg510,00€100mg715,00€1mL*10mM (DMSO)167,00€Netivudine
CAS :Netivudine, a potent NRTI with anti-varicella activity, treats HIV by inhibiting reverse transcriptase, reducing viral load.Formule :C12H14N2O6Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :282.25DS18561882
CAS :DS18561882: Potent MTHFD2 inhibitor (IC50=0.0063), inhibits MTHFD1 (IC50=0.57), good oral kinetics.Formule :C28H31F3N4O6SDegré de pureté :98.19% - >99.99%Couleur et forme :SolidMasse moléculaire :608.63Ref: TM-T11103
1mg109,00€5mg260,00€10mg409,00€25mg737,00€50mg1.198,00€100mg1.611,00€1mL*10mM (DMSO)358,00€DSS30
CAS :DSS30 is a P25/CDK5 inhibitor that reduces β-amyloid secretion to help prevent Alzheimer's.Formule :C16H14ClNO3S2Degré de pureté :99.19% - 99.4%Couleur et forme :SolidMasse moléculaire :367.87INDY
CAS :INDY is an ATP-competitive inhibitor of Dyrk1A and Dyrk1B with IC50s of 0.24 μM and 0.23 μM and a Ki of 0.18 μM for Dyrk1A ATP pocket, respectively.Formule :C12H13NO2SDegré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :235.3AS 1892802
CAS :AS 1892802, a ROCK inhibitor: IC50 - 52nM (hROCK2), 57nM (rROCK2), 122nM (hROCK1). Fast antinociceptive effect similar to Tramadol, Diclofenac.Formule :C20H19N3O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :333.38Ref: TM-T22037
1mg49,00€5mg92,00€10mg166,00€25mg358,00€50mg530,00€100mg758,00€200mg1.044,00€1mL*10mM (DMSO)109,00€YK-2-69
CAS :YK-2-69 selectively blocks DYRK2 at Lys-231 and Lys-234, outperforming enzalutamide in prostate cancer treatment.Formule :C25H27FN8OSDegré de pureté :98.61% - 99.64%Couleur et forme :SolidMasse moléculaire :506.6116-9e
CAS :116-9e (MAL2-11B) is an Hsp70 chaperone DNAJA1 inhibitor with antiviral properties, inhibits SV40 replication, and can be used to study cancer drug resistance.Formule :C31H32N2O5Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :512.6Ref: TM-T25770
1mg50,00€5mg105,00€10mg170,00€25mg355,00€50mg595,00€100mg862,00€200mg1.153,00€1mL*10mM (DMSO)34,00€SJB3-019A
CAS :SJB3-019A is a potent, potent and novel ubiquitin-specific protease 1 (USP1) inhibitor, which promotes ID1 degradation and cytotoxicity in K562 cells 5 timesFormule :C16H8N2O3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :276.25Ref: TM-T12926
1mg77,00€2mg101,00€5mg168,00€10mg253,00€25mg416,00€50mg580,00€100mg783,00€200mg1.054,00€CRT0066854 hydrochloride
CAS :CRT0066854 HCl inhibits atypical PKCs; IC50: PKCι 132 nM, PKCζ 639 nM, ROCK-II 620 nM.Formule :C24H27Cl2N5SDegré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :488.48Ref: TM-T10888
1mg57,00€5mg122,00€10mg192,00€25mg324,00€50mg459,00€100mg642,00€200mg888,00€1mL*10mM (DMSO)146,00€Abemaciclib metabolite M20
CAS :Abemaciclib metabolite M20 (CDK4/6-IN-4) 是 Abemaciclib 的活性代谢物。 Abemaciclib metabolite M20 是一种特异性 CDK4/6 抑制剂,可用于癌症治疗的相关研究。Formule :C27H32F2N8ODegré de pureté :98.1% - 99.08%Couleur et forme :SolidMasse moléculaire :522.59Rho-Kinase-IN-1
CAS :Rho-Kinase-IN-1: ROCK inhibitor, Ki of 30.5 nM (ROCK1) & 3.9 nM (ROCK2), used in research for diseases linked to cell overgrowth and inflammation.Formule :C20H24N4SDegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :352.5Ref: TM-T12721
1mg71,00€5mg138,00€10mg205,00€25mg358,00€50mg502,00€100mg665,00€200mg893,00€1mL*10mM (DMSO)105,00€ERCC1-XPF-IN-2
CAS :ERCC1-XPF-IN-2: Nucleotide repair active, boosts cisplatin, inhibits ERCC1-XPF (IC50: 0.6 μM).
Formule :C15H13Cl2NO3Degré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :326.17Ref: TM-T60904
2mg40,00€5mg60,00€10mg96,00€25mg187,00€50mg311,00€100mg472,00€200mg658,00€500mg1.026,00€Cytembena
CAS :Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.Formule :C11H8BrNaO4Degré de pureté :99.7%Couleur et forme :White PowderMasse moléculaire :307.07CD532
CAS :CD532: Potent Aurora A inhibitor, IC50=45 nM, blocks kinase activity, degrades MYCN, interacts with AURKA, studies cancer.Formule :C26H25F3N8ODegré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :522.52USP30 inhibitor 11
CAS :USP30 inhibitor 11 (USP30-IN-11) is a USP30 inhibitor that inhibits SVA and can be used in studies of cancer, mitochondrial dysfunction and Parkinson's.Formule :C17H16N6O2SDegré de pureté :98.84% - 99.59%Couleur et forme :SolidMasse moléculaire :368.41HA-1004
CAS :HA-1004 is a inhibitor of PKG, PKA, PKC and MLC.Formule :C12H15N5O2SDegré de pureté :99.56% - 99.63%Couleur et forme :SolidMasse moléculaire :293.34ProINDY
CAS :ProINDY (Pro-indy) is a potent DYRK inhibitor that activates NFAT for the study of Down syndrome.Formule :C14H15NO3SDegré de pureté :97.19%Couleur et forme :SolidMasse moléculaire :277.34ML 315
CAS :ML 315 is a selective Clk and DYRK inhibitor with potential anticancer activity for the study of neurological disorders.Formule :C18H13Cl2N3O2Degré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :374.22CLK-IN-T3
CAS :CLK-IN-T3 is an inhibitor of CLK1, CLK2, and CLK3 with IC50s of 0.67, 15, and 110 nM. CLK-IN-T3 exhibits anti-cancer activity.Formule :C28H30N6O2Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :482.58Ref: TM-T14980
1mg47,00€2mg62,00€5mg92,00€10mg160,00€25mg289,00€50mg505,00€100mg787,00€200mg1.063,00€Poloxin-2
CAS :Poloxin-2 is a potent and selective Plk1 PBD inhibitor with anti-tumour activity that reduces the protein level of Plk1 in HeLa cells.Formule :C16H15NO3Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :269.3Haspin-IN-3
CAS :Haspin-IN-3 is a potent haspin inhibitor with an IC50 of 14 nM.Haspin-IN-3 has anticancer activity.
Formule :C16H10N2O3Degré de pureté :98.78%Couleur et forme :SolidMasse moléculaire :278.26TTP-8307
CAS :TTP-8307 is an antiviral compound that inhibits the replication of rhinoviruses and enteroviruses and is used in the study of viral infections.Formule :C27H21FN4ODegré de pureté :98.95%Couleur et forme :SolidMasse moléculaire :436.48Ref: TM-T13221
1mg100,00€5mg236,00€10mg380,00€25mg740,00€50mg1.108,00€100mg1.791,00€200mg2.412,00€1mL*10mM (DMSO)286,00€COH34
CAS :COH34 (1-[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol) is a selective inhibitor of PARG with an IC50 of 0.37 nM and a Kd of 0.547 μM.Formule :C18H15NOSDegré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :293.38ZIM
CAS :ZIM, from 4-Aminoantipyrine, induces DNA and chromosomal damage, cell death, and phagocytosis, with potential in cancer therapy.Formule :C20H19N3O3Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :349.38DDRI-18
CAS :DDRI-18 is an inhibitor that regulates the DNA damage response, has anticancer activity, and inhibits non-homologous end-joining (NHEJ) DNA repair.Formule :C26H20N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :416.48P22074
CAS :P22074 is a USP7 inhibitor. It is not an active antagonist like its halogenated related compounds. p22074 has antitumour activity.Formule :C12H9NO3S2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :279.33Ref: TM-T28284
1mg137,00€5mg314,00€10mg427,00€25mg600,00€50mg798,00€100mg1.099,00€200mg1.468,00€1mL*10mM (DMSO)239,00€PCSK9-IN-10
CAS :PCSK9-IN-10: potent oral PCSK9 inhibitor (IC50 = 6.4 µM), upregulates LDLR, curbs atherosclerosis, for hyperlipidemia research.Formule :C18H23N5O4Degré de pureté :99.06%Couleur et forme :SoildMasse moléculaire :373.41Ref: TM-T72025
2mg39,00€5mg60,00€10mg96,00€25mg170,00€50mg266,00€100mg391,00€200mg555,00€1mL*10mM (DMSO)62,00€CDK9-IN-10
CAS :CDK9-IN-10 is a potent CDK9 inhibitor and the ligand for the PROTAC CDK9 degrader-2.Formule :C22H16O5Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :360.36CRT-0105950
CAS :CRT-0105950 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.Formule :C21H16ClN3OSDegré de pureté :99.78% - 99.86%Couleur et forme :SolidMasse moléculaire :393.89Ref: TM-T23917
1mg65,00€5mg140,00€10mg216,00€25mg439,00€50mg707,00€100mg1.130,00€1mL*10mM (DMSO)156,00€DENV-IN-5
CAS :Denv-in-5 is an effective and selective dengue virus (DENV) inhibitor with EC50 values of 1.47, 9.23, 7.08, 8.91 μM for denV-I-IV and 0.1512 μM for HIV-1IIIB.Formule :C23H25ClF2N4OSDegré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :478.99Ref: TM-T63143
1mg424,00€5mg964,00€10mg1.288,00€25mg1.890,00€50mg2.322,00€100mg3.060,00€1mL*10mM (DMSO)898,00€dCeMM2
CAS :dCeMM2 degrades glue by promoting CDK12-cyclin K ubiquitination and degradation via CRL4B ligase interaction.Formule :C16H11ClN6OSDegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :370.82Ref: TM-T61477
1mg34,00€5mg74,00€10mg113,00€25mg236,00€50mg404,00€100mg600,00€500mg1.279,00€1mL*10mM (DMSO)104,00€UMK57
CAS :UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds,Formule :C17H17N3SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :295.4GRK6-IN-1
CAS :GRK6-IN-1 (compound 18) is a potent GRK6 blocker, with an IC50 of 120 nM, showing promise for multiple myeloma research.Formule :C22H23ClN6O2Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :438.91Ref: TM-T62518
1mg54,00€5mg114,00€10mg178,00€25mg409,00€50mg708,00€100mg1.153,00€1mL*10mM (DMSO)126,00€SB-747651A Dihydrochloride
CAS :SB-747651A dihydrochloride, an MSK1 inhibitor (IC50=11 nM), also targets PRK2, RSK1, p70S6K, ROCK-II; potential in inflammation study.Formule :C16H24Cl2N8ODegré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :415.32Ref: TM-T9652
1mg70,00€5mg146,00€10mg207,00€25mg349,00€50mg497,00€100mg675,00€500mgÀ demander1mL*10mM (DMSO)160,00€TC-S 7005
CAS :TC-S 7005 is an effective inhibitor of Polo-like kinases (IC50s: 214 nM, 4 nM and 24 nM for Plk1, Plk2, and Plk3).Formule :C21H17N3O3Degré de pureté :99.516%Couleur et forme :SolidMasse moléculaire :359.38Ref: TM-T17008
1mg57,00€2mg84,00€5mg125,00€10mg188,00€25mg354,00€50mg532,00€100mg712,00€500mgÀ demander1mL*10mM (DMSO)138,00€SMN-C2
CAS :SMN-C2, a SMN2 gene splicing regulator, is an RNA-binding ligand that regulates pre-mRNA splicing and has potential for studying spinal muscular atrophy.Formule :C24H27N5O2Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :417.5Ref: TM-T73475
1mg105,00€5mg250,00€10mg401,00€25mg795,00€50mg982,00€100mg1.324,00€1mL*10mM (DMSO)268,00€AS-0141
CAS :AS-0141 (Cdc7-IN-6) 是一种有效的 Cdc7 激酶抑制剂 (IC50=4 nM),具有抗肿瘤活性。Cdc7 是一种丝氨酸苏氨酸蛋白激酶酶,在细胞周期中对 DNA 复制的启动至关重要。Formule :C21H22F3N5O4Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :465.435'-ODMT cEt m5U Phosphoramidite (Amidite)
CAS :5'-ODMT cEt m5U Phosphoramidite Amidite, a locked nucleic acid (LNA) analog, demonstrates exceptional safety and antisense activity [1] [2].Formule :C42H51N4O9PCouleur et forme :SolidMasse moléculaire :786.85PD-321852
CAS :PD-321852, a Chk1 inhibitor, boosts gemcitabine's effect in pancreatic cancer cells, varying from minimal in Panc1 to >30-fold in MiaPaCa2.Formule :C24H19Cl2N3O3Couleur et forme :SolidMasse moléculaire :468.33SJ26
CAS :SJ26 is a Wnt1 inhibitor known for its anticancer activity. It inhibits the expression of WNT1 and the downstream signaling pathways mediated by WNT1 in a G-quadruplex structure-dependent manner, thereby suppressing the migratory activity of cancer cells.Formule :C29H32ClN3OCouleur et forme :SolidMasse moléculaire :474.04TNH
CAS :TNH, a dimeric compound, possesses the ability to penetrate living cells and facilitate the recruitment of proteins into cellular structures [1].Formule :C39H57ClN6O13Couleur et forme :SolidMasse moléculaire :853.36HQ005
CAS :HQ005, a potent CCNK degrader, exhibits an impressive DC50 value of 0.041 µM and functions as a molecular-glue degrader.Formule :C15H15N5O2S2Couleur et forme :SolidMasse moléculaire :361.44Mps1-IN-10
CAS :Mps1-IN-6 (Compound 9) is a highly effective Mps1 inhibitor with an IC50 value of 6.4 nM and exhibits significant anti-proliferation and anti-tumor effects onFormule :C24H27N7O2Couleur et forme :SolidMasse moléculaire :445.52DYRKs-IN-2
CAS :DYRKs-IN-2 has antitumor activity. DYRKs-IN-2 is a potent DYRKs inhibitor with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively.Formule :C32H38ClN9O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :632.16αvβ1 integrin-IN-2
CAS :αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively.Formule :C29H38N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.64Anti-hepatic fibrosis agent 2
CAS :Compound 6k, also known as Anti-hepatic fibrosis agent 2, is an orally active inhibitor of the COL1A1 enzyme and exerts anti-fibrogenic effects by targeting theFormule :C26H41N3OCouleur et forme :SolidMasse moléculaire :411.62SB-267268
CAS :SB-267268: αvβ3 inhibitor (IC50: 0.68 nM human, 0.29 nM mouse), blocks αvβ3/αvβ5 integrins (Ki: 0.9 nM human, 0.5 nM monkey αvβ3, 0.7 nM human αvβ5).Formule :C22H24F3N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :451.44MS-444
CAS :MS-444 (BE-34776) is an MLCK and HuR inhibitor with antitumor activity that can be used to study triple-negative breast cancer and colorectal cancer.Formule :C13H10O4Degré de pureté :99.45% - 99.45%Couleur et forme :SolidMasse moléculaire :230.22ROCK2-IN-2
CAS :ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of <1 μM).Formule :C18H12N6OSDegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :360.39Ref: TM-T12747
1mg50,00€5mg111,00€10mg177,00€25mg304,00€50mg447,00€100mg692,00€200mg888,00€1mL*10mM (DMSO)136,00€PLK1/p38γ-IN-1
CAS :PLK1/p38γ-IN-1 (compound 14) serves as a dual inhibitor targeting both PLK1 and p38γ kinases, effectively suppressing the proliferation of human hepatocellularFormule :C21H26ClN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.9PDD00031705
CAS :PDD00031705 is a benzimidazolone core cell-inactive Poly (ADP-ribose) glycohydrolase (PARG) inhibitor.Formule :C20H22N6O3S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :490.62
