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Cycle cellulaire/point de contrôle

Cycle cellulaire/point de contrôle

Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.

Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"

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3909 produits trouvés pour "Cycle cellulaire/point de contrôle"

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  • CDK4-IN-2

    CAS :
    CDK4-IN-2 (A17) is a potent inhibitor of CDK4, exhibiting K i and IC 50 values of less than 10 nM and is utilized in cancer research [1].
    Formule :C22H26F2N6O4S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :508.54

    Ref: TM-T79046

    5mg
    À demander
    50mg
    À demander
  • CDK9-IN-9

    CAS :
    CDK9-IN-9 is a potent and selective CDK9 inhibitor (IC50: 1.8 nM) with anti-cancer activity. It inhibits CDK2 (IC50: 155 nM).
    Formule :C22H23F2N5O2S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :459.51

    Ref: TM-T10747

    25mg
    1.780,00€
  • LDC3140

    CAS :
    LDC3140 is a potent inhibitor of Cyclin-dependent kinase 7 (CDK7).
    Formule :C23H33N7O
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :423.55

    Ref: TM-T27805

    25mg
    1.872,00€
    50mg
    2.452,00€
    100mg
    3.230,00€
  • MC-Val-Cit-PAB-Ispinesib

    CAS :
    MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent Eg5 inhibitor and a click chemistry reagent [1].
    Formule :C59H71ClN10O10
    Couleur et forme :Solid
    Masse moléculaire :1115.71

    Ref: TM-T84703

    10mg
    À demander
    50mg
    À demander
  • Homouridine

    CAS :
    Homouridine, an analogue of uridine, functions as an intermediate in the synthesis of MMP-2 inhibitor (compound I, IC50 = 150 μM).
    Formule :C10H14N2O6
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :258.23

    Ref: TM-T79190

    5mg
    À demander
    50mg
    À demander
  • SB-267268

    CAS :
    SB-267268: αvβ3 inhibitor (IC50: 0.68 nM human, 0.29 nM mouse), blocks αvβ3/αvβ5 integrins (Ki: 0.9 nM human, 0.5 nM monkey αvβ3, 0.7 nM human αvβ5).
    Formule :C22H24F3N3O4
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :451.44

    Ref: TM-T16851

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • KSP-IA

    CAS :
    KSP-IA is a potent, specific, allosteric, and cell-active KSP inhibitor.
    Formule :C21H22F2N2O
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :356.41

    Ref: TM-T24271

    25mg
    1.908,00€
    50mg
    2.502,00€
    100mg
    3.330,00€
  • Integrin Antagonists 27

    CAS :
    Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist. It has a binding affinity of 18 nM and as a novel anticancer agent.
    Formule :C24H20N4O5
    Couleur et forme :Solid
    Masse moléculaire :444.44

    Ref: TM-T15584

    2mg
    178,00€
    5mg
    313,00€
    1mL*10mM (DMSO)
    344,00€
    25mg
    1.026,00€
    50mg
    1.341,00€
    100mg
    1.791,00€
  • G4/HDAC-IN-1


    G4/HDAC-IN-1, a G4/HDAC dual inhibitor, IC50 1.1 µM, blocks TNBC growth, useful in cancer research.
    Formule :C36H49ClFN7O4
    Couleur et forme :Solid
    Masse moléculaire :698.27

    Ref: TM-T72946

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • OXA-06 hydrochloride

    CAS :
    OXA-06 hydrochloride, an ATP-competitive ROCK inhibitor, impedes anchorage-dependent growth and invasion in non-small cell lung cancer cell lines. It effectively inhibits cofilin phosphorylation without inducing apoptosis [1].
    Formule :C21H20Cl2FN3
    Couleur et forme :Solid
    Masse moléculaire :404.31

    Ref: TM-T84882

    10mg
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    50mg
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  • NITD008

    CAS :
    NITD008 (7-Deaza-2'-C-acetylene-adenosine) is an adenosine nucleoside inhibitor with antiviral activity that inhibits dengue and Zika viruses.
    Formule :C13H14N4O4
    Degré de pureté :98.04%
    Couleur et forme :Solid
    Masse moléculaire :290.27

    Ref: TM-T16325

    1mg
    139,00€
  • Cdk4 Inhibitor

    CAS :
    PD 0332991, an unsymmetrical indolocarbazole compound, is cell-permeable and exhibits antiproliferative effects by functioning as a potent, selective, reversible, and ATP-competitive inhibitor of Cdk4/D1 (IC 50 = 76 nM). Although it can inhibit other Cdks, such as Cdk2/E and Cdk1/B, effectiveness requires higher concentrations (IC 50 = 520 nM and 2.1 µM, respectively) and demonstrates minimal activity against CaMKII, PKA, or GSK-3β (IC 50 ≥ 12.4 µM). PD 0332991 efficiently inhibits tumor cell growth in HCT-116 and NCI-H460 cell lines with an IC 50 < 3.0 µM, primarily through blocking Rb phosphorylation and inducing G1 cell cycle arrest.
    Formule :C20H10BrN3O2
    Couleur et forme :Solid
    Masse moléculaire :404.2

    Ref: TM-T84413

    10mg
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    50mg
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  • Luvixasertib hydrochloride

    CAS :
    CFI-402257 hydrochloride, a highly selective and orally bioavailable inhibitor targeting TTK/Mps1, demonstrates an in vitro IC50 value of 1.7 nM against TTK. This compound exhibits anti-cancer activity [1].
    Formule :C28H31ClN6O3
    Couleur et forme :Solid
    Masse moléculaire :535.04

    Ref: TM-T84711

    10mg
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    50mg
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  • Pelitrexol

    CAS :
    Pelitrexol (AG2037) is a GARFT inhibitor, which can inhibit the activity of mTORC1, block the cell cycle in the s-phase, with antiproliferative activity,NSCLC .
    Formule :C20H25N5O6S
    Degré de pureté :98.03%
    Couleur et forme :Solid
    Masse moléculaire :463.51

    Ref: TM-T14147

    5mg
    469,00€
    1mL*10mM (DMSO)
    567,00€
    25mg
    1.378,00€
    50mg
    1.791,00€
    100mg
    2.980,00€
  • FAICAR

    CAS :
    FAICAR (5-Formamidoimidazole-4-carboxamide ribotide), a purine nucleotide, plays a crucial role in metabolic processes.
    Formule :C10H15N4O9P
    Couleur et forme :Solid
    Masse moléculaire :366.22

    Ref: TM-T84746

    10mg
    À demander
    50mg
    À demander
  • Galidesivir hydrochloride

    CAS :
    Galidesivir hydrochloride is an inhibitor of viral RNA-dependent RNA polymerase (RdRp). It inhibits SARS-CoV-2 by tightly binding to its RdRp.
    Formule :C11H16ClN5O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :301.73

    Ref: TM-T10491L

    25mg
    1.765,00€
    50mg
    2.295,00€
    100mg
    3.681,00€
  • 5-Iodo-indirubin-3'-monoxime

    CAS :
    5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase (IC50s
    Formule :C16H10IN3O2
    Couleur et forme :Solid
    Masse moléculaire :403.17

    Ref: TM-T10172

    5mg
    268,00€
    25mg
    888,00€
    50mg
    1.224,00€
    100mg
    1.674,00€
  • SZ-015268

    CAS :
    SZ-015268: CDK7 inhibitor, IC50=23.56 nM; hinders HCC70, OVCAR-3, HCT116, HCC1806 cell growth; strong anti-tumor effect.
    Formule :C25H38N8O3
    Couleur et forme :Solid
    Masse moléculaire :498.62

    Ref: TM-T63383

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • Anti-hepatic fibrosis agent 2

    CAS :
    Compound 6k, also known as Anti-hepatic fibrosis agent 2, is an orally active inhibitor of the COL1A1 enzyme and exerts anti-fibrogenic effects by targeting the
    Formule :C26H41N3O
    Couleur et forme :Solid
    Masse moléculaire :411.62

    Ref: TM-T83064

    5mg
    À demander
    50mg
    À demander
  • DUB-IN-7

    CAS :
    DUB-IN-7 (compound 43), a deubiquitinating enzyme (DUB) inhibitor, has utility in researching diseases driven by aberrant JAK2 activity, including leukemia [1].
    Formule :C17H19N5O
    Couleur et forme :Solid
    Masse moléculaire :309.37

    Ref: TM-T79672

    5mg
    À demander
    50mg
    À demander
  • CCT-251921

    CAS :
    CCT-251921 is a potent, selective, and orally bioavailable CDK8 inhibitor (IC50: 2.3 nM).
    Formule :C21H23ClN6O
    Degré de pureté :99.07%
    Couleur et forme :Solid
    Masse moléculaire :410.9

    Ref: TM-T14901

    1mg
    90,00€
    1mL*10mM (DMSO)
    192,00€
    5mg
    210,00€
    10mg
    308,00€
    25mg
    520,00€
    50mg
    745,00€
    100mg
    1.018,00€
  • USP7-IN-13

    CAS :
    USP7-IN-13 (Compound 101), a USP7 inhibitor, exhibits an IC50 range of 0.2-1 μM and is applicable in researching multiple myeloma [1].
    Formule :C24H28N4O3
    Couleur et forme :Solid
    Masse moléculaire :420.5

    Ref: TM-T84710

    10mg
    À demander
    50mg
    À demander
  • GSK2646264

    CAS :
    GSK2646264 (Compound 44) inhibits SYK (pIC50=7.1) and kinases like LCK, LRRK2; penetrates skin.
    Formule :C24H26N2O2
    Couleur et forme :Solid
    Masse moléculaire :374.48

    Ref: TM-T61527

    25mg
    1.900,00€
    50mg
    3.025,00€
  • Carotegrast

    CAS :
    Carotegrast, an orally available α4 integrin receptor inhibitor, has anti-inflammatories activities.
    Formule :C27H24Cl2N4O5
    Couleur et forme :Solid
    Masse moléculaire :555.41

    Ref: TM-T14876

    25mg
    775,00€
    50mg
    1.009,00€
    100mg
    1.449,00€
  • CDK9-IN-8

    CAS :
    CDK9-IN-8 is a highly potent and selective CDK9 inhibitor (IC50: 12 nM).
    Formule :C31H32FN7O3
    Degré de pureté :99.54%
    Couleur et forme :Solid
    Masse moléculaire :569.63

    Ref: TM-T10746

    1mg
    35,00€
    5mg
    85,00€
    10mg
    110,00€
    25mg
    178,00€
    50mg
    244,00€
    100mg
    321,00€
  • αvβ1 integrin-IN-2

    CAS :
    αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively.
    Formule :C29H38N4O4
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :506.64

    Ref: TM-T79792

    5mg
    À demander
    50mg
    À demander
  • USP1-IN-6

    CAS :
    USP1-IN-6 (Compound 11) functions as a potent USP1 inhibitor, exhibiting an IC50 value of less than 50 nM.
    Formule :C29H27F3N8O
    Couleur et forme :Solid
    Masse moléculaire :560.57

    Ref: TM-T79796

    5mg
    À demander
    50mg
    À demander
  • CDK4/6-IN-17

    CAS :
    CDK4/6-IN-17 (compound 12) is an orally bioavailable inhibitor of CDK4/6, demonstrating potent activity with IC50 values between 10-100 nM in BE(2) cells.
    Formule :C27H28F4N8
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :540.56

    Ref: TM-T79112

    5mg
    À demander
    50mg
    À demander
  • CDK8-IN-3

    CAS :
    CDK8-IN-3 is an inhibitor of CDK8.
    Formule :C22H23N5O2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :389.45

    Ref: TM-T14917

    25mg
    999,00€
    50mg
    1.305,00€
    100mg
    1.972,00€
  • 3-Hydroxyxanthone

    CAS :
    3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical vein
    Formule :C13H8O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :212.2

    Ref: TM-T78548

    5mg
    À demander
    50mg
    À demander
  • H3B-968

    CAS :
    H3B-968 is a potent inhibitor of Werner syndrome protein (WRN) with an IC50 of approximately 10 nM, effectively targeting its helicase, ATPase, and exonuclease
    Formule :C22H18F6N4O4S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :548.46

    Ref: TM-T78938

    5mg
    À demander
    50mg
    À demander
  • SC-52012

    CAS :
    SC-52012 is a novel and potent fibrinogen receptor antagonist, an RGD mimetic, which inhibits platelet aggregation.
    Formule :C25H30N4O6
    Degré de pureté :97.20%
    Couleur et forme :Solid
    Masse moléculaire :482.53

    Ref: TM-T12857

    1mg
    630,00€
    5mg
    1.620,00€
  • hDHODH-IN-1

    CAS :
    hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.
    Formule :C17H14N2O2
    Degré de pureté :99.97%
    Couleur et forme :Solid
    Masse moléculaire :278.31

    Ref: TM-T11546

    1mg
    34,00€
    5mg
    71,00€
    1mL*10mM (DMSO)
    78,00€
    10mg
    103,00€
    25mg
    200,00€
    50mg
    290,00€
    100mg
    404,00€
    200mg
    545,00€
  • 12R-LOX-IN-1

    CAS :
    12R-LOX-IN-1 (Compound 4a), with an IC50 of 28.25 µM, is an inhibitor of 12R-LOX.
    Formule :C15H11NO2
    Couleur et forme :Solid
    Masse moléculaire :237.25

    Ref: TM-T83457

    5mg
    À demander
    50mg
    À demander
  • Alatrofloxacin

    CAS :
    Alatrofloxacin is a prodrug of trovafloxacin.
    Formule :C26H25F3N6O5
    Couleur et forme :Solid
    Masse moléculaire :558.51

    Ref: TM-T23703

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • MOMA-341

    CAS :
    MOMA-341, ATP-competitive WRN allosteric inhibitor (Cys727 site), induces DNA damage and tumor regression in dMMR/MSI-H models, for solid tumors.
    Formule :C28H26F4N6O3
    Couleur et forme :Solid
    Masse moléculaire :570.54

    Ref: TM-T210496

    1mg
    405,00€
    5mg
    973,00€
    10mg
    1.314,00€
    25mg
    1.953,00€
    50mg
    3.213,00€
  • PLK1/p38γ-IN-1

    CAS :
    PLK1/p38γ-IN-1 (compound 14) serves as a dual inhibitor targeting both PLK1 and p38γ kinases, effectively suppressing the proliferation of human hepatocellular
    Formule :C21H26ClN3O2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :387.9

    Ref: TM-T81441

    5mg
    À demander
    50mg
    À demander
  • MS-444

    CAS :
    MS-444 (BE-34776) is an MLCK and HuR inhibitor with antitumor activity that can be used to study triple-negative breast cancer and colorectal cancer.
    Formule :C13H10O4
    Degré de pureté :99.45% - 99.45%
    Couleur et forme :Solid
    Masse moléculaire :230.22

    Ref: TM-T16145

    2mg
    720,00€
  • ROCK-IN-7

    CAS :
    ROCK-IN-7 (compound 9) serves as a ROCK kinase inhibitor and is utilized in the investigation of ocular conditions, including glaucoma and retinal diseases [1].
    Formule :C17H17N3O2S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :327.4

    Ref: TM-T79080

    5mg
    À demander
    50mg
    À demander
  • Gly-Arg-Gly-Asp-Ser TFA

    CAS :
    Gly-Arg-Gly-Asp-Ser (TFA), osteopontin domain, binds αvβ3 and αvβ5 integrins; IC50s: ~5 μM, ~6.5 μM.
    Formule :C19H31F3N8O11
    Couleur et forme :Solid
    Masse moléculaire :604.49

    Ref: TM-T75761

    5mg
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    50mg
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  • DNA polymerase-IN-1

    CAS :
    DNA polymerase-IN-1 exhibits antiproliferative activity against tumor cells and inhibits Taq DNA polymerase as a DNA polymerase inhibitor.
    Formule :C10H7ClO4
    Degré de pureté :99.16%
    Couleur et forme :Solid
    Masse moléculaire :226.61

    Ref: TM-T80644

    1mg
    175,00€
    5mg
    434,00€
    10mg
    622,00€
    25mg
    973,00€
    50mg
    1.341,00€
    100mg
    1.773,00€
  • BI-1950

    CAS :
    BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.
    Formule :C32H26Cl2FN7O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :646.5

    Ref: TM-T14558

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • Myt1-IN-2

    CAS :
    Myt1-IN-2, a highly potent Myt1 inhibitor, exhibits remarkable anticancer properties with an IC50 value below 10 nM (WO2021195782A1; compound 28) [1].
    Formule :C18H16N6O2S
    Couleur et forme :Solid
    Masse moléculaire :380.42

    Ref: TM-T61615

    25mg
    1.927,00€
    50mg
    2.507,00€
    100mg
    3.168,00€
  • ROCK2-IN-2

    CAS :
    ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of <1 μM).
    Formule :C18H12N6OS
    Degré de pureté :99.65%
    Couleur et forme :Solid
    Masse moléculaire :360.39

    Ref: TM-T12747

    1mg
    50,00€
    5mg
    111,00€
    1mL*10mM (DMSO)
    136,00€
    10mg
    177,00€
    25mg
    304,00€
    50mg
    447,00€
    100mg
    692,00€
    200mg
    888,00€
  • Chroman 1

    CAS :
    Chroman 1 is a potent inhibitor of ROCK1 (IC50 = 52 pM) and ROCK2 (IC50 = 1 pM).
    Formule :C24H28N4O4
    Degré de pureté :99.67% - 99.84%
    Couleur et forme :Solid
    Masse moléculaire :436.5

    Ref: TM-T14960

    1mg
    73,00€
    5mg
    160,00€
    1mL*10mM (DMSO)
    173,00€
    10mg
    250,00€
    25mg
    430,00€
    50mg
    645,00€
    100mg
    888,00€
  • FT671

    CAS :
    FT671 is a non-covalent, selective USP7 inhibitor, disrupts the stability of USP7 substrates including MDM2, elevates p53, induces p21, inhibits tumor growth.
    Formule :C24H23F4N7O3
    Degré de pureté :99.76%
    Couleur et forme :Solid
    Masse moléculaire :533.48

    Ref: TM-T12621L

    1mg
    À demander
    10mg
    À demander
    5mg
    131,00€
    25mg
    464,00€
    50mg
    803,00€
    100mg
    1.388,00€
  • Xylocydine

    CAS :
    Xylocydine is a novel Cdk inhibitor that induces apoptosis in HCC, suppresses tumor growth, and is non-toxic to other tissues.
    Formule :C12H14BrN5O5
    Couleur et forme :Solid
    Masse moléculaire :388.17

    Ref: TM-T68875

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • RAD51-IN-4

    CAS :
    RAD51-IN-4, a potent RAD51 inhibitor, may be useful in researching mitochondrial defect-related conditions.
    Formule :C31H34FN5O5S2
    Couleur et forme :Solid
    Masse moléculaire :639.76

    Ref: TM-T73107

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • Mevociclib

    CAS :
    Mevociclib (SY-1365) is a highly selective covalent inhibitor of CDK7. SY-1365 possesses therapeutic potential in both hematological and solid tumors.
    Formule :C31H35ClN8O2
    Degré de pureté :98.02% - 98.02%
    Couleur et forme :Solid
    Masse moléculaire :587.11

    Ref: TM-T13044

    1mg
    180,00€
  • DHX9-IN-6

    CAS :
    DHX9-IN-6 is a highly effective ATP-dependent RNA helicase A (DHX9) inhibitor, used in cancer research.
    Formule :C23H18ClFN4O4S2
    Degré de pureté :99.71%
    Couleur et forme :Solid
    Masse moléculaire :533

    Ref: TM-T86202

    1mg
    187,00€
    5mg
    465,00€
    10mg
    692,00€
    25mg
    1.074,00€
    50mg
    1.454,00€
  • ML 315 hydrochloride

    CAS :

    ML 315, a selective dual inhibitor targeting CDK (Cyclin-Dependent Kinase) and DYRK (Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase) with IC50 values of 68 nM and 282 nM, respectively, is utilized in research pertaining to cancer and neurological diseases [1].

    Formule :C18H14Cl3N3O2
    Couleur et forme :Solid
    Masse moléculaire :410.682

    Ref: TM-T84712

    10mg
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  • Cytarabine 5′-monophosphate

    CAS :
    Cytarabine 5′-monophosphate (ara-CMP), an active metabolite of the nucleoside analog cytarabine formed by deoxycytidine kinase, is incorporated into DNA by DNA polymerase α, significantly slowing DNA synthesis. It inhibits nuclear and mitochondrial DNA replication in S. cerevisiae at 15 mM and improves survival in an L1210 murine leukemia model at 3.5-75.1 mg/kg.
    Formule :C9H14N3O8P
    Couleur et forme :Solid
    Masse moléculaire :323.198

    Ref: TM-T84932

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  • DNA Gyrase-IN-8

    CAS :
    DNA Gyrase-IN-8 is a potent inhibitor of DNA gyrase, demonstrating antimicrobial activity with an IC50 of 8.45 µM [1].
    Formule :C19H14BrN5O
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :408.25

    Ref: TM-T78712

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  • NTRC 0066-0

    CAS :
    NTRC 0066-0 is a TTK inhibitor that can be used in cancer research.
    Formule :C33H39N7O2
    Degré de pureté :98.30%
    Couleur et forme :Solid
    Masse moléculaire :565.71

    Ref: TM-T28216

    2mg
    139,00€
  • ATN-161

    CAS :
    ATN-161 is an integrin α5β1 binding peptide and antagonist that inhibits VEGF-induced hCECs migration and angiogenesis.
    Formule :C23H35N9O8S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :597.64

    Ref: TM-T10398

    1mg
    48,00€
    5mg
    90,00€
  • 5′-Guanylyl methylenediphosphonate sodium

    CAS :
    5′-Guanylyl methylenediphosphonate (sodium) serves as a GTP analogue and acts as a specific, competitive inhibitor of the GTP reaction in protein synthesis [1].
    Formule :C11H15N5Na3O13P3
    Couleur et forme :Solid
    Masse moléculaire :587.15

    Ref: TM-T83299

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  • DAM-IN-1

    CAS :
    DMA-IN-1 is a DNA adenine methyltransferase (DAM) inhibitor with an IC50 value of 48 μM.
    Formule :C16H17NO4
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :287.31

    Ref: TM-T82614

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  • Cdc7-IN-12

    CAS :
    Cdc7-IN-12, a sub-1 nM CDC7 inhibitor, may aid cancer research; hinders COLO205 cell growth (IC50: 100-1000 nM).
    Formule :C16H14N2O2S
    Couleur et forme :Solid
    Masse moléculaire :298.36

    Ref: TM-T60659

    25mg
    1.927,00€
    50mg
    2.507,00€
    100mg
    3.168,00€
  • WRN inhibitor 5

    CAS :
    WRN Inhibitor 5 (Example 157), a cyclic vinyl sulfone-based compound, serves as an inhibitor of Werner Syndrome ATP-dependent helicase enzyme (WRN).
    Formule :C23H20N2O6S
    Couleur et forme :Solid
    Masse moléculaire :452.48

    Ref: TM-T80772

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  • CDK7-IN-14

    CAS :
    CDK7-IN-14 (compound 3) is a pyrimidine-derived CDK7 inhibitor applicable for studying cancers associated with transcriptional dysregulation.
    Formule :C22H24F3N6OP
    Degré de pureté :99.24% - 99.48%
    Couleur et forme :Solid
    Masse moléculaire :476.43

    Ref: TM-T63108

    1mg
    415,00€
    5mg
    964,00€
    10mg
    1.288,00€
    25mg
    1.918,00€
  • CCT241533

    CAS :
    CCT241533 is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).
    Formule :C23H27FN4O4
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :442.48

    Ref: TM-T10718

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • Senexin C

    CAS :
    Senexin C is a CDK8/19 inhibitor with anticancer activity.Senexin C inhibits the growth of MV4-11 leukemia cells.
    Formule :C28H27N5O
    Degré de pureté :98.06%
    Couleur et forme :Solid
    Masse moléculaire :449.55

    Ref: TM-T62702

    1mg
    170,00€
    5mg
    430,00€
    1mL*10mM (DMSO)
    475,00€
    10mg
    628,00€
  • MU-380

    CAS :
    MU-380 is an effective and selective inhibitor of CHK1.
    Formule :C15H15BrF3N7
    Couleur et forme :Solid
    Masse moléculaire :430.23

    Ref: TM-T24506

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • DNA gyrase B-IN-3

    CAS :
    DNA gyrase B-IN-3 (Compound A), with an IC50 of less than 10 nM, acts as an inhibitor of bacterial DNA gyrase B and exhibits antibacterial activity against Gram
    Formule :C14H9Cl2N3O4S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :386.21

    Ref: TM-T78776

    25mg
    1.504,00€
    50mg
    1.963,00€
    100mg
    2.520,00€
  • Votoplam

    CAS :
    Votoplam functions as a gene splicing modulator, employed in the inhibition of Huntington's disease [1].
    Formule :C21H25N9O
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :419.48

    Ref: TM-T79865

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  • SB-743921 free base

    CAS :
    SB-743921, a kinesin spindle protein (KSP) inhibitor, is used potentially for the treatment of non-Hodgkin's lymphoma (NHL).
    Formule :C31H33ClN2O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :517.06

    Ref: TM-T28694

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • Brodimoprim

    CAS :
    Brodimoprim is an inhibitor of dihydrofolate reductase(DHFR).
    Formule :C13H15BrN4O2
    Degré de pureté :98% - 99.71%
    Couleur et forme :Solid
    Masse moléculaire :339.19

    Ref: TM-T19858

    1mg
    39,00€
    5mg
    84,00€
    10mg
    120,00€
    25mg
    200,00€
    50mg
    299,00€
    100mg
    432,00€
  • DHX9-IN-4

    CAS :
    DHX9-IN-4 is an ATP-dependent RNA helicase DHX9 inhibitor used in cancer research.
    Formule :C21H22ClN5O4S2
    Degré de pureté :98.12%
    Couleur et forme :Solid
    Masse moléculaire :508.01

    Ref: TM-T86200

    1mg
    236,00€
    5mg
    587,00€
    10mg
    837,00€
    25mg
    1.251,00€
    50mg
    1.693,00€
  • Myt1-IN-3

    CAS :
    Myt1-IN-3 is a potent inhibitor of Myt1 (IC50 <10 nM) [1].
    Formule :C18H19N5O2
    Couleur et forme :Solid
    Masse moléculaire :337.38

    Ref: TM-T61056

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • Spirofylline

    CAS :
    Spirofylline is an agent of bronchodilator, has the potential for asthma and bronchitis and emphysema treatment.
    Formule :C24H28N6O5
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :480.52

    Ref: TM-T13899

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • Nε-(1-Carboxyethyl)-L-lysine

    CAS :
    Nε-(1-Carboxyethyl)-L-lysine (CEL) is an advanced glycation end-product (AGE). Exposure to CEL reduces glutamate uptake and S100B secretion in the hippocampus.
    Formule :C9H18N2O4
    Couleur et forme :Solid
    Masse moléculaire :218.25

    Ref: TM-T85157

    1mg
    99,00€
    5mg
    236,00€
    10mg
    379,00€
  • CDK9-IN-29

    CAS :
    CDK9-IN-29 (compound Z11) is a potent inhibitor of CDK9, exhibiting high kinase selectivity and an IC50 value of 3.20 nM.
    Formule :C29H33F2N5O4
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :553.6

    Ref: TM-T82757

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  • USP1-IN-5

    CAS :
    USP1-IN-5 (compound 10) is a potent inhibitor of both USP1, with an IC50 of less than 50 nM, and MDA-MB-436 cells, where it also exhibits an IC50 of less than
    Formule :C27H23F3N8O
    Couleur et forme :Solid
    Masse moléculaire :532.52

    Ref: TM-T79795

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  • G-5758

    CAS :
    G-5758 is an orally active IRE1α inhibitor with an IC50 of 38 nM for XBP1s. It is used in studies involving multiple myeloma models [KMS-11], demonstrating good tolerance in rats at oral doses up to 500 mg/kg. G-5758 exhibits pharmacodynamic effects comparable to those induced by IRE1 knockdown.
    Formule :C27H24F4N6O3S
    Couleur et forme :Solid
    Masse moléculaire :588.58

    Ref: TM-T87983

    25mg
    1.584,00€
    50mg
    2.115,00€
    100mg
    2.673,00€
  • GW814408X

    CAS :
    GW814408X, a kinase chemical genome group (KCGS) compound, inhibits the AURKC kinase, which is involved in cell cycle progression, checkpoint regulation, and cell division. It exhibits cell line-dependent toxicity, such as cytotoxic effects on HeLa cells, and acts as a protein kinase inhibitor across ATP-dependent and -independent luciferases, potentially impacting Fluc reporter assays [1].
    Formule :C19H16N6O
    Masse moléculaire :344.37

    Ref: TM-T86538

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • 5'-ODMT cEt m5U Phosphoramidite (Amidite)

    CAS :
    5'-ODMT cEt m5U Phosphoramidite Amidite, a locked nucleic acid (LNA) analog, demonstrates exceptional safety and antisense activity [1] [2].
    Formule :C42H51N4O9P
    Couleur et forme :Solid
    Masse moléculaire :786.85

    Ref: TM-T74705

    10mg
    36,00€
    25mg
    49,00€
    50mg
    68,00€
    100mg
    101,00€
  • RNA polymerase II-IN-1

    CAS :
    RNA polymerase II-IN-1 (19iv), an amatoxin, inhibits Pol II at 36.66 nM IC50, is more toxic to cancer cells, less to normal cells than α-Amanitin.
    Formule :C38H53N11O12S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :887.96

    Ref: TM-T74630

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  • 5'-ODMT cEt N-Bzm5 C Phosphoramidite (Amidite)

    CAS :
    5'-ODMT cEt N-Bzm5 C Phosphoramidite is a strong modified nucleic acid analog for antisense oligos.
    Formule :C49H56N5O9P
    Couleur et forme :Solid
    Masse moléculaire :889.97

    Ref: TM-T74704

    1mg
    251,00€
    5mg
    623,00€
    10mg
    889,00€
    25mg
    1.314,00€
    50mg
    1.783,00€
    100mg
    2.403,00€
  • αvβ6 integrin inhibitor 2

    CAS :
    αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.
    Formule :C21H30N4O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :386.49

    Ref: TM-T79140

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  • PVZB1194

    CAS :
    PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through
    Formule :C13H9F4NO2S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :319.28

    Ref: TM-T78125

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  • DCB-3503

    CAS :
    DCB-3503, a tylophorine analog, may fight cancer and aid immunosuppression by hindering protein synthesis and modulating HSC70 ATPase function.
    Formule :C24H27NO5
    Couleur et forme :Solid
    Masse moléculaire :409.47

    Ref: TM-T27128

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • Zaurategrast

    CAS :
    Zaurategrast (CDP323) is an oral α4-integrin antagonist that blocks VCAM-1 interactions and is used to study immune cell trafficking.
    Formule :C26H25BrN4O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :521.41

    Ref: TM-T17286

    1mg
    72,00€
    5mg
    166,00€
  • LX7101 hydrochloride

    CAS :
    LX7101 is a potent inhibitor of both LIM kinase (LIMK) 1 and 2, and Rho-associated kinase 1 (ROCK1) and ROCK2, with IC50 values of 32, 4.3, 69, and 32 nM, respectively. It is selective, demonstrated by its lack of cross-reactivity in a panel of binding assays involving 78 receptors, transporters, and an additional 430 kinases, at a concentration of 10 μM. The topical administration of LX7101 (3 μl of a 1 mg/ml solution) to the eye has been shown to reduce intraocular pressure in a dexamethasone-induced mouse model of glaucoma.
    Formule :C23H29N7O3HCl
    Couleur et forme :Solid
    Masse moléculaire :488

    Ref: TM-T85304

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  • Synstatin (92-119)

    CAS :
    Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 and
    Formule :C133H207N35O46
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :3032.27

    Ref: TM-T78064

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  • ROCK-IN-9

    CAS :
    ROCK-IN-9 (Compound T345), a ROCK inhibitor, exhibits cytotoxicity in HepG2 cells with an IC50 of 40.8 μM.
    Formule :C20H20FN5O2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :381.4

    Ref: TM-T79833

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  • L 738167

    CAS :
    L 738167 is a potent antagonist of the long-acting fibrinogen receptor.
    Formule :C25H34N6O6S
    Couleur et forme :Solid
    Masse moléculaire :546.64

    Ref: TM-T24353

    25mg
    1.908,00€
    50mg
    2.502,00€
    100mg
    3.330,00€
  • PTC258

    CAS :
    PTC258 is a specific, orally active modulator of the splicing of the Elongator complex protein 1 gene (ELP1), enhancing its expression both in vitro and in vivo
    Formule :C16H18ClN3S2
    Couleur et forme :Solid
    Masse moléculaire :351.92

    Ref: TM-T81355

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  • Mps1-IN-10

    CAS :
    Mps1-IN-6 (Compound 9) is a highly effective Mps1 inhibitor with an IC50 value of 6.4 nM and exhibits significant anti-proliferation and anti-tumor effects on
    Formule :C24H27N7O2
    Couleur et forme :Solid
    Masse moléculaire :445.52

    Ref: TM-T77779

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  • 2'-Deoxypseudoisocytidine

    CAS :
    2'-Deoxypseudoisocytidine is a nucleoside analogue.
    Formule :C9H13N3O4
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :227.22

    Ref: TM-T10099

    25mg
    1.504,00€
    50mg
    1.963,00€
    100mg
    2.520,00€
  • WRN inhibitor 1

    CAS :
    WRN Inhibitor 1 (example 7) is an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN), selectively targeting its helicase domain.
    Formule :C16H13FN2O4S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :348.35

    Ref: TM-T79107

    5mg
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    50mg
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  • TC-A 2317 hydrochloride

    CAS :
    TC-A 2317 HCl inhibits Aurora A kinase (Ki 1.2 nM) over Aurora B (Ki 101 nM), displaying antitumor effects.
    Formule :C19H29ClN6O
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :392.93

    Ref: TM-T23426

    50mg
    4.123,00€
  • ROCK2-IN-7

    CAS :
    ROCK2 inhibitor is a chemical compound associated with the therapeutic management of psoriasis.
    Formule :C26H28FN5O
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :445.53

    Ref: TM-T81261

    5mg
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  • BMT-090605 hydrochloride

    CAS :
    BMT-090605 HCl: AAK1 inhibitor (IC50=0.6 nM), also targets BIKE (IC50=45 nM) & GAK (IC50=60 nM), with potential in neuropathic pain research.
    Formule :C21H25ClN4O2
    Couleur et forme :Solid
    Masse moléculaire :400.91

    Ref: TM-T61941

    25mg
    1.629,00€
    50mg
    2.125,00€
    100mg
    3.250,00€
  • BMT-090605

    CAS :
    BMT-090605: AAK1 inhibitor (IC50=0.6 nM), also affects BIKE (45 nM) and GAK (60 nM), has antinociceptive properties.
    Formule :C21H24N4O2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :364.44

    Ref: TM-T14691

    25mg
    1.908,00€
    50mg
    2.502,00€
    100mg
    3.330,00€
  • Lerociclib

    CAS :
    Lerociclib (G1T38) is a CDK4/6 inhibitor with anticancer and antitumor activities, inhibiting CDK4/CyclinD1 and CDK6/CyclinD3.
    Formule :C26H34N8O
    Degré de pureté :99%
    Couleur et forme :Solid
    Masse moléculaire :474.6

    Ref: TM-T11345

    1mg
    35,00€
    5mg
    75,00€
    10mg
    114,00€
    25mg
    208,00€
    50mg
    334,00€
    100mg
    494,00€
  • COH1

    CAS :
    COH1 is a ribonucleotide reductase (RR) inhibitor utilized in research pertaining to cancer, mitochondrial diseases, and neurodegenerative disorders [1].
    Formule :C11H10N2O3S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :250.27

    Ref: TM-T78814

    5mg
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  • Leucettinib-92

    CAS :
    Leucettinib-92 is a multi-kinase inhibitor of DYRK and CLK families with differential nanomolar activity, supporting studies of kinase signaling regulation.
    Formule :C21H22N4OS
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :378.49

    Ref: TM-T79562

    1mg
    308,00€
    5mg
    745,00€
    10mg
    1.035,00€
    25mg
    1.513,00€
    50mg
    2.062,00€
    100mg
    2.790,00€
  • L-739758

    CAS :
    L-739758 is a glycoprotein IIb/IIIa inhibitor.
    Formule :C22H26N4O5S3
    Couleur et forme :Solid
    Masse moléculaire :522.66

    Ref: TM-T70281

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • CI 972 anhydrous

    CAS :
    CI 972 anhydrous is an inhibitor of purine nucleoside phosphorylase (PNP) (Ki: 0.83 μM) used as a T cell-selective immunosuppressive agent.
    Formule :C11H12ClN5OS
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :297.76

    Ref: TM-T14964

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • CDK7-IN-22

    CAS :
    CDK7-IN-22 (compound 101) is a selective CDK7 inhibitor that exhibits antitumor activity, demonstrating specificity for CDK7 [1].
    Formule :C22H25F3N6
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :430.47

    Ref: TM-T79169

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€