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Cycle cellulaire/point de contrôle

Cycle cellulaire/point de contrôle

Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.

Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"

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3912 produits trouvés pour "Cycle cellulaire/point de contrôle"

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  • H3B-968

    CAS :
    H3B-968 is a potent inhibitor of Werner syndrome protein (WRN) with an IC50 of approximately 10 nM, effectively targeting its helicase, ATPase, and exonuclease
    Formule :C22H18F6N4O4S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :548.46

    Ref: TM-T78938

    5mg
    À demander
    50mg
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  • USP7-IN-1

    CAS :
    USP7-IN-1 is a selective and reversible ubiquitin-specific protease 7 (USP7) inhibitor (IC50 = 77 μM).
    Formule :C23H24ClN3O3
    Degré de pureté :99.82%
    Couleur et forme :Solid
    Masse moléculaire :425.91

    Ref: TM-T13268

    1mg
    92,00€
    5mg
    178,00€
    1mL*10mM (DMSO)
    207,00€
    10mg
    269,00€
    25mg
    429,00€
    50mg
    610,00€
    100mg
    820,00€
    200mg
    1.071,00€
  • CT1113

    CAS :
    CT1113, a potent inhibitor of both USP28 and USP25, effectively reduces MYC levels in vivo and demonstrates anti-tumor efficacy in a mouse pancreatic cancer CDX
    Formule :C25H29N5O2S
    Couleur et forme :Solid
    Masse moléculaire :463.6

    Ref: TM-T79187

    5mg
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    50mg
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  • DNA Gyrase-IN-8

    CAS :
    DNA Gyrase-IN-8 is a potent inhibitor of DNA gyrase, demonstrating antimicrobial activity with an IC50 of 8.45 µM [1].
    Formule :C19H14BrN5O
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :408.25

    Ref: TM-T78712

    5mg
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    50mg
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  • PLK1-IN-7

    CAS :
    PLK1-IN-7 (compound 30e) is a potent inhibitor exhibiting an IC50 value of 0.66 nM and demonstrates significant antiproliferative and antitumor activities [1].
    Formule :C24H24F4N8O2
    Couleur et forme :Solid
    Masse moléculaire :532.49

    Ref: TM-T81440

    5mg
    À demander
    50mg
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  • 5-Iodo-indirubin-3'-monoxime

    CAS :
    5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase (IC50s
    Formule :C16H10IN3O2
    Couleur et forme :Solid
    Masse moléculaire :403.17

    Ref: TM-T10172

    5mg
    268,00€
    25mg
    888,00€
    50mg
    1.224,00€
    100mg
    1.674,00€
  • USP1-IN-5

    CAS :
    USP1-IN-5 (compound 10) is a potent inhibitor of both USP1, with an IC50 of less than 50 nM, and MDA-MB-436 cells, where it also exhibits an IC50 of less than
    Formule :C27H23F3N8O
    Couleur et forme :Solid
    Masse moléculaire :532.52

    Ref: TM-T79795

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    50mg
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  • CDK7-IN-22

    CAS :
    CDK7-IN-22 (compound 101) is a selective CDK7 inhibitor that exhibits antitumor activity, demonstrating specificity for CDK7 [1].
    Formule :C22H25F3N6
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :430.47

    Ref: TM-T79169

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • Cytidine 3'-monophosphate

    CAS :
    Cytidine 3'-monophosphate, a ribonucleotide, results from the hydrolysis of cytidine 2',3'-cyclic monophosphate via RNase—a process that cytidine 3'-monophosphate itself inhibits. Additionally, it can be dephosphorylated to cytidine by 3'-nucleotidase.
    Formule :C9H14N3O8P
    Couleur et forme :Solid
    Masse moléculaire :323.2

    Ref: TM-T85002

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  • DNA gyrase B-IN-3

    CAS :
    DNA gyrase B-IN-3 (Compound A), with an IC50 of less than 10 nM, acts as an inhibitor of bacterial DNA gyrase B and exhibits antibacterial activity against Gram
    Formule :C14H9Cl2N3O4S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :386.21

    Ref: TM-T78776

    25mg
    1.504,00€
    50mg
    1.963,00€
    100mg
    2.520,00€
  • RNA polymerase II-IN-1

    CAS :
    RNA polymerase II-IN-1 (19iv), an amatoxin, inhibits Pol II at 36.66 nM IC50, is more toxic to cancer cells, less to normal cells than α-Amanitin.
    Formule :C38H53N11O12S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :887.96

    Ref: TM-T74630

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  • BMT-090605

    CAS :
    BMT-090605: AAK1 inhibitor (IC50=0.6 nM), also affects BIKE (45 nM) and GAK (60 nM), has antinociceptive properties.
    Formule :C21H24N4O2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :364.44

    Ref: TM-T14691

    25mg
    1.908,00€
    50mg
    2.502,00€
    100mg
    3.330,00€
  • Aurora Kinases-IN-4

    CAS :
    Aurora Kinases-IN-4 (Compound 11c) is a covalent, ATP-competitive inhibitor of aurora kinase A with an IC50 value of 1.7 nM.
    Formule :C26H28N8O
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :468.55

    Ref: TM-T78753

    25mg
    1.504,00€
    50mg
    1.963,00€
    100mg
    2.520,00€
  • Tirofiban HCl

    CAS :

    Tirofiban HCl is an antagonist of platelet glycoprotein-IIb/IIIa receptor.

    Formule :C22H37ClN2O5S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :477.06

    Ref: TM-T20552

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • NSC15520

    CAS :
    NSC15520 is an RPA inhibitor that inhibits helical destabilization of double-stranded DNA oligonucleotides and can be used to study DNA damage repair.
    Formule :C24H34O6
    Couleur et forme :Solid
    Masse moléculaire :418.52

    Ref: TM-T81640

    1mg
    105,00€
    5mg
    304,00€
    10mg
    355,00€
    25mg
    750,00€
  • ROCK2-IN-2

    CAS :
    ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of <1 μM).
    Formule :C18H12N6OS
    Degré de pureté :99.65%
    Couleur et forme :Solid
    Masse moléculaire :360.39

    Ref: TM-T12747

    1mg
    50,00€
    5mg
    111,00€
    1mL*10mM (DMSO)
    136,00€
    10mg
    177,00€
    25mg
    304,00€
    50mg
    447,00€
    100mg
    692,00€
    200mg
    888,00€
  • 8-NH2-ATP tetrasodium

    CAS :
    8-NH2-ATP tetrasodium, an inactive ATP variant, originates from 8-NH2-Ado tetrasodium, which triggers the apoptosis-associated cleavage of poly (ADP-ribose) polymerase [1] [2].
    Formule :C10H13N6Na4O13P3
    Couleur et forme :Solid
    Masse moléculaire :610.12

    Ref: TM-T84731

    10mg
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  • KY386

    CAS :
    KY386 is a potent and selective DHX33 helicase inhibitor with an IC50 value of 19 nM.
    Formule :C21H19N5O2S
    Couleur et forme :Solid
    Masse moléculaire :405.47

    Ref: TM-T81967

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  • AVG-233

    CAS :
    AVG-233 is an RNA-dependent RNA polymerase (RdRp) inhibitor with antiviral activity for the study of respiratory syncytial virus infections.
    Formule :C26H22ClN5O3
    Degré de pureté :99%
    Couleur et forme :Solid
    Masse moléculaire :487.94

    Ref: TM-T63253

    1mg
    190,00€
  • Palmitoyl 3-carbacyclic phosphatidic acid

    CAS :
    Palmitoyl 3-carbacyclic phosphatidic acid, a palmitoylated Carba-like cyclophosphatidic acid and LPA (lysophosphatidic acid) analog, possesses distinct biological activities compared to LPA, including the inhibition of RhoA activation and melanoma cell migration. This compound has demonstrated efficacy in inhibiting experimental lung metastasis and reducing tumor nodule counts in a B16-F0 xenograft mouse model [1].
    Formule :C20H39O5P
    Couleur et forme :Solid
    Masse moléculaire :390.49

    Ref: TM-T84483

    10mg
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  • Spirofylline

    CAS :
    Spirofylline is an agent of bronchodilator, has the potential for asthma and bronchitis and emphysema treatment.
    Formule :C24H28N6O5
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :480.52

    Ref: TM-T13899

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • MOMA-341

    CAS :
    MOMA-341, ATP-competitive WRN allosteric inhibitor (Cys727 site), induces DNA damage and tumor regression in dMMR/MSI-H models, for solid tumors.
    Formule :C28H26F4N6O3
    Couleur et forme :Solid
    Masse moléculaire :570.54

    Ref: TM-T210496

    1mg
    405,00€
    5mg
    973,00€
    10mg
    1.314,00€
    25mg
    1.953,00€
    50mg
    3.213,00€
  • USP7-IN-13

    CAS :
    USP7-IN-13 (Compound 101), a USP7 inhibitor, exhibits an IC50 range of 0.2-1 μM and is applicable in researching multiple myeloma [1].
    Formule :C24H28N4O3
    Couleur et forme :Solid
    Masse moléculaire :420.5

    Ref: TM-T84710

    10mg
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  • Pencitabine

    CAS :
    Pen is an oral cancer drug that blocks DNA synthesis by inhibiting key enzymes and integrating into DNA.
    Formule :C15H20F3N3O6
    Couleur et forme :Solid
    Masse moléculaire :395.33

    Ref: TM-T61839

    25mg
    1.927,00€
    50mg
    2.507,00€
    100mg
    3.168,00€
  • WEE1-IN-4

    CAS :
    Wee1 Inhibitor I is an ATP-binding site-targeting Wee1 inhibitor.
    Formule :C20H11ClN2O3
    Couleur et forme :Solid
    Masse moléculaire :362.77

    Ref: TM-T23869

    1mg
    852,00€
  • CDK4/6-IN-17

    CAS :
    CDK4/6-IN-17 (compound 12) is an orally bioavailable inhibitor of CDK4/6, demonstrating potent activity with IC50 values between 10-100 nM in BE(2) cells.
    Formule :C27H28F4N8
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :540.56

    Ref: TM-T79112

    5mg
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    50mg
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  • pppApG

    CAS :
    pppApG serves as an initial substrate for the synthesis of vRNA (viral RNA) and cRNA (complementary RNA), with applications in influenza virus research [1].
    Formule :C20H28N10O20P4
    Couleur et forme :Solid
    Masse moléculaire :852.39

    Ref: TM-T81413

    5mg
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    50mg
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  • GSK2850163

    CAS :
    GSK2850163 is a novel inhibitor of inositol-requiring enzyme-1 alpha (IRE1α) which can inhibit RNase activity and IRE1α kinase activity (IC50s: 200 and 20 nM).
    Formule :C24H29Cl2N3O
    Degré de pureté :99.04%
    Couleur et forme :Solid
    Masse moléculaire :446.41

    Ref: TM-T11488

    5mg
    66,00€
    1mL*10mM (DMSO)
    73,00€
    10mg
    105,00€
    25mg
    215,00€
    50mg
    340,00€
    100mg
    512,00€
  • Mefenidil

    CAS :
    Mefenidil (McN-2378), a selective cerebral vasodilator, was shown to increase CBF in healthy brains without stimulating O2 uptake in a dog anesthesia model.
    Formule :C12H11N3
    Degré de pureté :98.27%
    Couleur et forme :Solid
    Masse moléculaire :197.24

    Ref: TM-T33272

    1mg
    137,00€
    5mg
    314,00€
    10mg
    427,00€
    25mg
    600,00€
    50mg
    798,00€
    100mg
    1.099,00€
    200mg
    1.468,00€
  • 3-Hydroxyxanthone

    CAS :
    3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical vein
    Formule :C13H8O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :212.2

    Ref: TM-T78548

    5mg
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    50mg
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  • Nε-(1-Carboxyethyl)-L-lysine

    CAS :
    Nε-(1-Carboxyethyl)-L-lysine (CEL) is an advanced glycation end-product (AGE). Exposure to CEL reduces glutamate uptake and S100B secretion in the hippocampus.
    Formule :C9H18N2O4
    Couleur et forme :Solid
    Masse moléculaire :218.25

    Ref: TM-T85157

    1mg
    99,00€
    5mg
    236,00€
    10mg
    379,00€
  • LX7101

    CAS :
    LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM).
    Formule :C23H29N7O3
    Degré de pureté :99.08%
    Couleur et forme :Solid
    Masse moléculaire :451.52

    Ref: TM-T15798

    1mg
    58,00€
  • m-Se3

    CAS :
    m-Se3 is a potent, selective inhibitor of c-MYC transcription with demonstrated capability to inhibit tumor growth and exhibit anti-cancer activity [1].
    Formule :C29H23IN2Se
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :605.37

    Ref: TM-T79872

    5mg
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    50mg
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  • Lotrafiban hydrochloride

    CAS :
    Lotrafiban hydrochloride is an platelet glycoprotein IIb/IIIa blocker with oral activity.
    Formule :C23H33ClN4O4
    Couleur et forme :Solid
    Masse moléculaire :464.99

    Ref: TM-T27846

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • Zaurategrast

    CAS :
    Zaurategrast (CDP323) is an oral α4-integrin antagonist that blocks VCAM-1 interactions and is used to study immune cell trafficking.
    Formule :C26H25BrN4O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :521.41

    Ref: TM-T17286

    1mg
    72,00€
    5mg
    166,00€
  • CCT241533

    CAS :
    CCT241533 is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).
    Formule :C23H27FN4O4
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :442.48

    Ref: TM-T10718

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • (±)9(10)-DiHOME

    CAS :
    (±)9(10)-DiHOME, the diol derivative of (±)9(10)-EpOME—a cytochrome P450-derived epoxide of linoleic acid also known as leukotoxin—is formed through the action of soluble epoxide hydrolase (sEH) in neutrophils. It exhibits toxicity towards Sf21 cells expressing sEH as well as tolacZ-expressing control cells, differing from leukotoxin which only harms sEH-containing cells. Furthermore, combined exposure to 9(10)- and 12(13)-DiHOME leads to cell death in rabbit renal proximal tubule cells by disrupting mitochondrial respiration, and causes lung injury, respiratory distress, and mortality in mice, highlighting its role as a toxic lipid mediator. Specifically, 9(10)-DiHOME has been associated with acute respiratory distress syndrome (ARDS), a severe and often deadly complication in patients with major burns. Elevated levels of this compound have been detected in the bronchoalveolar lavage fluid (BALF) of women, but not men, with chronic obstructive pulmonary disease (COPD), and its levels are also increased in patients with allergic asthma, indicating its significance in respiratory conditions.
    Formule :C18H34O4
    Couleur et forme :Solid
    Masse moléculaire :314.5

    Ref: TM-T84633

    10mg
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  • WRN inhibitor 2

    CAS :
    WRN Inhibitor 2 (example 118), a potent inhibitor of the WRN (Werner Syndrome ATP-dependent helicase enzyme), exhibits a pIC50 value of 7.0 or greater [1].
    Formule :C15H11F3N2O5S2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :420.38

    Ref: TM-T79178

    5mg
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    50mg
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  • CDK/HDAC-IN-3

    CAS :
    CDK/HDAC-IN-3 is an orally active dual inhibitor of HDACs and CDKs, offering potent and selective inhibition of CDK9, CDK12, CDK13, HDAC1, HDAC2, and HDAC3,
    Formule :C24H18Cl2N6O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :509.34

    Ref: TM-T78906

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • GSPT1 degrader-2

    CAS :
    GSPT1 degrader-2 is a potent degrader of GSPT1 [1].
    Formule :C22H20ClN3O5
    Couleur et forme :Solid
    Masse moléculaire :441.86

    Ref: TM-T82253

    5mg
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    50mg
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  • Sovesudil

    CAS :
    Sovesudil (PHP-201) is a potent ROCK inhibitor with IC50 of 3.7 nM/2.3 nM for ROCK-I/II; lowers IOP without hyperemia.
    Formule :C23H22FN3O3
    Couleur et forme :Solid
    Masse moléculaire :407.44

    Ref: TM-T62036

    25mg
    1.710,00€
    50mg
    2.232,00€
    100mg
    3.501,00€
  • SB-743921 free base

    CAS :
    SB-743921, a kinesin spindle protein (KSP) inhibitor, is used potentially for the treatment of non-Hodgkin's lymphoma (NHL).
    Formule :C31H33ClN2O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :517.06

    Ref: TM-T28694

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • NVS-SM2

    CAS :
    NVS-SM2 boosts SMN2 splicing, enhances exon 7 inclusion, and raises SMN protein levels orally.
    Formule :C23H30N6O
    Couleur et forme :Solid
    Masse moléculaire :406.52

    Ref: TM-T33764

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • CDK9-IN-23

    CAS :
    CDK9-IN-23 (Example 4) is a potent inhibitor of CDK9, exhibiting an IC50 value of less than 20 nM [1].
    Formule :C22H25ClN4O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :428.91

    Ref: TM-T79037

    5mg
    À demander
    50mg
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  • MU-380

    CAS :
    MU-380 is an effective and selective inhibitor of CHK1.
    Formule :C15H15BrF3N7
    Couleur et forme :Solid
    Masse moléculaire :430.23

    Ref: TM-T24506

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • TC-A 2317 hydrochloride

    CAS :
    TC-A 2317 HCl inhibits Aurora A kinase (Ki 1.2 nM) over Aurora B (Ki 101 nM), displaying antitumor effects.
    Formule :C19H29ClN6O
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :392.93

    Ref: TM-T23426

    50mg
    4.123,00€
  • G4/HDAC-IN-1


    G4/HDAC-IN-1, a G4/HDAC dual inhibitor, IC50 1.1 µM, blocks TNBC growth, useful in cancer research.
    Formule :C36H49ClFN7O4
    Couleur et forme :Solid
    Masse moléculaire :698.27

    Ref: TM-T72946

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • PLK1/p38γ-IN-1

    CAS :
    PLK1/p38γ-IN-1 (compound 14) serves as a dual inhibitor targeting both PLK1 and p38γ kinases, effectively suppressing the proliferation of human hepatocellular
    Formule :C21H26ClN3O2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :387.9

    Ref: TM-T81441

    5mg
    À demander
    50mg
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  • QR-6401

    CAS :
    QR-6401, a selective macrocyclic CDK2 inhibitor, is orally active with IC50 values of 0.37 nM for CDK2/E1, 10 nM for CDK9/T1, 22 nM for CDK1/A2, 34 nM for CDK6/
    Formule :C19H23N5O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :369.42

    Ref: TM-T79014

    5mg
    À demander
    50mg
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  • Tacaciclib

    CAS :
    Tacaciclib is a cyclin-dependent kinase (CDK) inhibitor with observed antineoplastic activity [1].
    Formule :C30H36N6O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :528.65

    Ref: TM-T79862

    5mg
    À demander
    50mg
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  • Trovafloxacin mesylate

    CAS :
    Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).
    Formule :C21H19F3N4O6S
    Degré de pureté :99.18%
    Couleur et forme :Solid
    Masse moléculaire :512.46

    Ref: TM-T13231L

    1mg
    34,00€
    5mg
    74,00€
    1mL*10mM (DMSO)
    85,00€
    10mg
    113,00€
    25mg
    177,00€
    50mg
    346,00€
  • Palbociclib orotate

    CAS :
    Palbociclib (PD 0332991) orotate, an orally active selective inhibitor of CDK4 and CDK6, exhibits IC50 values of 11 and 16 nM, respectively.
    Formule :C29H33N9O6
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :603.63

    Ref: TM-T72507

    5mg
    À demander
    50mg
    À demander
  • SB-267268

    CAS :
    SB-267268: αvβ3 inhibitor (IC50: 0.68 nM human, 0.29 nM mouse), blocks αvβ3/αvβ5 integrins (Ki: 0.9 nM human, 0.5 nM monkey αvβ3, 0.7 nM human αvβ5).
    Formule :C22H24F3N3O4
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :451.44

    Ref: TM-T16851

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • 5'-ODMT cEt m5U Phosphoramidite (Amidite)

    CAS :
    5'-ODMT cEt m5U Phosphoramidite Amidite, a locked nucleic acid (LNA) analog, demonstrates exceptional safety and antisense activity [1] [2].
    Formule :C42H51N4O9P
    Couleur et forme :Solid
    Masse moléculaire :786.85

    Ref: TM-T74705

    10mg
    36,00€
    25mg
    49,00€
    50mg
    68,00€
    100mg
    101,00€
  • NITD008

    CAS :
    NITD008 (7-Deaza-2'-C-acetylene-adenosine) is an adenosine nucleoside inhibitor with antiviral activity that inhibits dengue and Zika viruses.
    Formule :C13H14N4O4
    Degré de pureté :98.04%
    Couleur et forme :Solid
    Masse moléculaire :290.27

    Ref: TM-T16325

    1mg
    139,00€
  • Butylparaben sodium

    CAS :
    Butylparaben sodium significantly impacts the later phases of spermatogenesis in the testes by impairing hormonal regulation and/or RNA and protein synthesis [1
    Formule :C11H13NaO3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :216.21

    Ref: TM-T82803

    5mg
    À demander
    50mg
    À demander
  • ML-099

    CAS :
    ML-099 is a pan Ras-related GTPases activator that activates Rac1, Ras, GTP-binding protein (Rab7), Rab2A and cell division cycle 42.
    Formule :C14H13NO2S
    Degré de pureté :99.73%
    Couleur et forme :Solid
    Masse moléculaire :259.32

    Ref: TM-T22991

    1mg
    46,00€
    2mg
    60,00€
    1mL*10mM (DMSO)
    88,00€
    5mg
    90,00€
    10mg
    144,00€
    25mg
    289,00€
    50mg
    462,00€
    100mg
    672,00€
  • Alatrofloxacin

    CAS :
    Alatrofloxacin is a prodrug of trovafloxacin.
    Formule :C26H25F3N6O5
    Couleur et forme :Solid
    Masse moléculaire :558.51

    Ref: TM-T23703

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • 3-Cyanovinylcarbazole phosphoramidite

    CAS :
    3-Cyanovinylcarbazole phosphoramidite: an antiviral, hinders viral DNA synthesis, modifies ribonucleotides.
    Formule :C50H53N4O6P
    Couleur et forme :Solid
    Masse moléculaire :836.95

    Ref: TM-T74188

    5mg
    873,00€
    50mg
    1.665,00€
    100mg
    2.250,00€
  • ROCK-IN-8

    CAS :
    ROCK-IN-8 (Example 4), a ROCK inhibitor, exhibits anti-inflammatory properties and is suitable for respiratory and gastro-intestinal disease research,
    Formule :C30H25FN4O4S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :556.61

    Ref: TM-T79809

    5mg
    À demander
    50mg
    À demander
  • CDK4-IN-2

    CAS :
    CDK4-IN-2 (A17) is a potent inhibitor of CDK4, exhibiting K i and IC 50 values of less than 10 nM and is utilized in cancer research [1].
    Formule :C22H26F2N6O4S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :508.54

    Ref: TM-T79046

    5mg
    À demander
    50mg
    À demander
  • TNH

    CAS :
    TNH, a dimeric compound, possesses the ability to penetrate living cells and facilitate the recruitment of proteins into cellular structures [1].
    Formule :C39H57ClN6O13
    Couleur et forme :Solid
    Masse moléculaire :853.36

    Ref: TM-T80972

    5mg
    À demander
    50mg
    À demander
  • 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)

    CAS :
    5'-ODMT cEt N-Bz A Phosphoramidite Amidite, a locked nucleic acid (LNA) analogue, exhibits hybridization and mismatch discrimination capabilities similar to LNA, and shows resistance to exonuclease digestion [1].
    Formule :C49H54N7O8P
    Couleur et forme :Solid
    Masse moléculaire :899.97

    Ref: TM-T74702

    1mg
    288,00€
    5mg
    702,00€
    10mg
    1.000,00€
    25mg
    1.478,00€
    50mg
    1.941,00€
    100mg
    2.617,00€
  • Leucettinib-92

    CAS :
    Leucettinib-92 is a multi-kinase inhibitor of DYRK and CLK families with differential nanomolar activity, supporting studies of kinase signaling regulation.
    Formule :C21H22N4OS
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :378.49

    Ref: TM-T79562

    1mg
    308,00€
    5mg
    745,00€
    10mg
    1.035,00€
    25mg
    1.513,00€
    50mg
    2.062,00€
    100mg
    2.790,00€
  • JNJ-26076713

    CAS :
    JNJ-26076713, an oral alpha V integrin blocker, may treat macular edema, AMD, and diabetic retinopathy.
    Formule :C29H38N4O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :490.64

    Ref: TM-T27670

    25mg
    4.374,00€
  • Myt1-IN-2

    CAS :
    Myt1-IN-2, a highly potent Myt1 inhibitor, exhibits remarkable anticancer properties with an IC50 value below 10 nM (WO2021195782A1; compound 28) [1].
    Formule :C18H16N6O2S
    Couleur et forme :Solid
    Masse moléculaire :380.42

    Ref: TM-T61615

    25mg
    1.927,00€
    50mg
    2.507,00€
    100mg
    3.168,00€
  • Xylocydine

    CAS :
    Xylocydine is a novel Cdk inhibitor that induces apoptosis in HCC, suppresses tumor growth, and is non-toxic to other tissues.
    Formule :C12H14BrN5O5
    Couleur et forme :Solid
    Masse moléculaire :388.17

    Ref: TM-T68875

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • Cdc7-IN-12

    CAS :
    Cdc7-IN-12, a sub-1 nM CDC7 inhibitor, may aid cancer research; hinders COLO205 cell growth (IC50: 100-1000 nM).
    Formule :C16H14N2O2S
    Couleur et forme :Solid
    Masse moléculaire :298.36

    Ref: TM-T60659

    25mg
    1.927,00€
    50mg
    2.507,00€
    100mg
    3.168,00€
  • Teclistamab

    CAS :
    Teclistamab(JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor on t-cells and the BCMA for relapsed and refractory multiple myeloma.
    Degré de pureté :95%
    Couleur et forme :Liquid
    Masse moléculaire :143.64 kDa

    Ref: TM-T76881

    1mg
    661,00€
    5mg
    1.525,00€
    10mg
    2.025,00€
    25mg
    3.000,00€
    50mg
    4.058,00€
    100mg
    5.470,00€
  • Bisindolylmaleimide X hydrochloride

    CAS :
    Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selective PKC inhibitor. It is also a potent CDK2 antagonist (IC50: 200 nM).
    Formule :C26H25ClN4O2
    Degré de pureté :99.23%
    Couleur et forme :Solid
    Masse moléculaire :460.96

    Ref: TM-T10550

    1mg
    56,00€
    5mg
    127,00€
    1mL*10mM (DMSO)
    140,00€
    10mg
    215,00€
    25mg
    411,00€
    50mg
    648,00€
  • TNP-351

    CAS :
    Tnp 351 is a novel antifolate drug being assessed for chemotherapy of lung cancer.
    Formule :C21H24N6O5
    Couleur et forme :Solid
    Masse moléculaire :440.45

    Ref: TM-T26283

    25mg
    1.730,00€
    50mg
    2.262,00€
    100mg
    2.945,00€
  • Myt1-IN-3

    CAS :
    Myt1-IN-3 is a potent inhibitor of Myt1 (IC50 <10 nM) [1].
    Formule :C18H19N5O2
    Couleur et forme :Solid
    Masse moléculaire :337.38

    Ref: TM-T61056

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • DNA polymerase-IN-3

    CAS :
    DNA polymerase-IN-3 (Compd 5b), a coumarin derivative, demonstrates inhibitory activity against Taq DNA polymerase and has potential applications in
    Formule :C13H12O4
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :232.23

    Ref: TM-T79308

    5mg
    À demander
    50mg
    À demander
  • TAS-114

    CAS :
    TAS-114 is a dUTPase and DPD inhibitor that modulates catabolic pathways to improve systemic availability of 5-FU.
    Formule :C21H29N3O6S
    Degré de pureté :99.76%
    Couleur et forme :Solid
    Masse moléculaire :451.54

    Ref: TM-T13089

    2mg
    269,00€
  • IIIM-290

    CAS :
    IIIM-290 is an oral CDK inhibitor (IC50s: 90 and 94 nM for CDK2/A and CDK9/T1).
    Formule :C23H21Cl2NO5
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :462.32

    Ref: TM-T11632

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • Diazoketone methotrexate

    CAS :
    Diazoketone methotrexate is an analog of methotrexate with potential antitumor activity.
    Formule :C21H22N10O4
    Couleur et forme :Solid
    Masse moléculaire :478.46

    Ref: TM-T25322

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • PD-321852

    CAS :
    PD-321852, a Chk1 inhibitor, boosts gemcitabine's effect in pancreatic cancer cells, varying from minimal in Panc1 to >30-fold in MiaPaCa2.
    Formule :C24H19Cl2N3O3
    Couleur et forme :Solid
    Masse moléculaire :468.33

    Ref: TM-T68981

    25mg
    1.908,00€
    50mg
    2.502,00€
    100mg
    3.330,00€
  • CDK4/6-IN-15

    CAS :
    CDK4/6-IN-15: Oral, selective CDK4/6 inhibitor, halts cancer cell growth, G1 arrest, suppresses Rb phosphorylation.
    Formule :C21H27FN8S
    Couleur et forme :Solid
    Masse moléculaire :442.56

    Ref: TM-T72928

    25mg
    3.889,00€
    50mg
    5.445,00€
    100mg
    7.624,00€
  • 5-DACTHF

    CAS :
    5,11-methenyltetrahydrohomofolate blocks GAR & AIR transformylase; used as an anti-purine drug.
    Formule :C19H24N6O6
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :432.43

    Ref: TM-T24980

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • BI-1950

    CAS :
    BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.
    Formule :C32H26Cl2FN7O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :646.5

    Ref: TM-T14558

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • SZ-015268

    CAS :
    SZ-015268: CDK7 inhibitor, IC50=23.56 nM; hinders HCC70, OVCAR-3, HCT116, HCC1806 cell growth; strong anti-tumor effect.
    Formule :C25H38N8O3
    Couleur et forme :Solid
    Masse moléculaire :498.62

    Ref: TM-T63383

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • PTC258

    CAS :
    PTC258 is a specific, orally active modulator of the splicing of the Elongator complex protein 1 gene (ELP1), enhancing its expression both in vitro and in vivo
    Formule :C16H18ClN3S2
    Couleur et forme :Solid
    Masse moléculaire :351.92

    Ref: TM-T81355

    5mg
    À demander
    50mg
    À demander
  • CI 972 anhydrous

    CAS :
    CI 972 anhydrous is an inhibitor of purine nucleoside phosphorylase (PNP) (Ki: 0.83 μM) used as a T cell-selective immunosuppressive agent.
    Formule :C11H12ClN5OS
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :297.76

    Ref: TM-T14964

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • Antifolate C1

    CAS :
    Antifolate C1 blocks purine creation, favors uptake via folate receptors/PCFT over RFC.
    Formule :C19H21N5O6S
    Couleur et forme :Solid
    Masse moléculaire :447.46

    Ref: TM-T26635

    25mg
    1.908,00€
    50mg
    2.502,00€
    100mg
    3.330,00€
  • VER-00158411

    CAS :
    VER-00158411 is a checkpoint kinase 1 and CHK2 inhibitor (IC50: 4.4 nM and 4.5 nM, respectively).
    Formule :C31H34N6O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :538.64

    Ref: TM-T17223

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • Anti-hepatic fibrosis agent 2

    CAS :
    Compound 6k, also known as Anti-hepatic fibrosis agent 2, is an orally active inhibitor of the COL1A1 enzyme and exerts anti-fibrogenic effects by targeting the
    Formule :C26H41N3O
    Couleur et forme :Solid
    Masse moléculaire :411.62

    Ref: TM-T83064

    5mg
    À demander
    50mg
    À demander
  • Methotrexate-γ-aspartate

    CAS :
    Methotrexate-gamma-aspartate has growth inhibitory effects. It is used in antibody-targeted liposomes.
    Formule :C24H27N9O8
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :569.53

    Ref: TM-T24457

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • CCT-251921

    CAS :
    CCT-251921 is a potent, selective, and orally bioavailable CDK8 inhibitor (IC50: 2.3 nM).
    Formule :C21H23ClN6O
    Degré de pureté :99.07%
    Couleur et forme :Solid
    Masse moléculaire :410.9

    Ref: TM-T14901

    1mg
    90,00€
    1mL*10mM (DMSO)
    192,00€
    5mg
    210,00€
    10mg
    308,00€
    25mg
    520,00€
    50mg
    745,00€
    100mg
    1.018,00€
  • Inixaciclib

    CAS :
    Inixaciclib is a potent CDK inhibitor, can be used to research anticancer.
    Formule :C26H30F2N6O
    Couleur et forme :Solid
    Masse moléculaire :480.55

    Ref: TM-T69662

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • Fosfluridine tidoxil

    CAS :
    Fosfluridine tidoxil, a thymidylate synthase inhibitor, is used potentially for the treatment of colorectal cancer, and breast cancer.
    Formule :C34H62FN2O10PS
    Couleur et forme :Solid
    Masse moléculaire :740.9

    Ref: TM-T27349

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • AAPK-25

    CAS :
    AAPK-25, a dual Aurora/PLK inhibitor, disrupts mitosis, induces apoptosis, and has antitumor properties.
    Formule :C21H13Cl2N3O2S
    Degré de pureté :97.05%
    Couleur et forme :Solid
    Masse moléculaire :442.32

    Ref: TM-T10215

    1mg
    54,00€
    5mg
    118,00€
    1mL*10mM (DMSO)
    131,00€
    10mg
    172,00€
    25mg
    313,00€
    50mg
    469,00€
    100mg
    680,00€
  • KIF18A-IN-7

    CAS :
    KIF18A-IN-7 is an orally active inhibitor targeting KIF18A, demonstrating potent inhibition with an IC50 value of 9.4 nM against the microtubule-dependent
    Formule :C27H35N3O5S2
    Couleur et forme :Soild
    Masse moléculaire :545.71

    Ref: TM-T73050

    25mg
    1.144,00€
    50mg
    1.485,00€
    100mg
    2.385,00€
  • 2'-Deoxypseudoisocytidine

    CAS :
    2'-Deoxypseudoisocytidine is a nucleoside analogue.
    Formule :C9H13N3O4
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :227.22

    Ref: TM-T10099

    25mg
    1.504,00€
    50mg
    1.963,00€
    100mg
    2.520,00€
  • Balapiravir hydrochloride

    CAS :
    Balapiravir HCl, an NS5B inhibitor, is used potentially for the treatment of HCV infection.
    Formule :C21H31ClN6O8
    Couleur et forme :Solid
    Masse moléculaire :530.96

    Ref: TM-T26736

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • Pelitrexol

    CAS :
    Pelitrexol (AG2037) is a GARFT inhibitor, which can inhibit the activity of mTORC1, block the cell cycle in the s-phase, with antiproliferative activity,NSCLC .
    Formule :C20H25N5O6S
    Degré de pureté :98.03%
    Couleur et forme :Solid
    Masse moléculaire :463.51

    Ref: TM-T14147

    5mg
    469,00€
    1mL*10mM (DMSO)
    567,00€
    25mg
    1.378,00€
    50mg
    1.791,00€
    100mg
    2.980,00€
  • PVZB1194

    CAS :
    PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through
    Formule :C13H9F4NO2S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :319.28

    Ref: TM-T78125

    5mg
    À demander
    50mg
    À demander
  • Lotrafiban

    CAS :
    Lotrafiban: Oral GP IIb/IIIa inhibitor for treating coronary and cerebrovascular disease.
    Formule :C23H32N4O4
    Couleur et forme :Solid
    Masse moléculaire :428.52

    Ref: TM-T62351

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • L-Methioninamide hydrochloride

    CAS :
    L-Methioninamide hydrochloride is a potent inhibitor of methionyl-tRNA synthetase that reduces the toxicity of CDDP.
    Formule :C5H13ClN2OS
    Degré de pureté :99.93%
    Couleur et forme :Solid
    Masse moléculaire :184.69

    Ref: TM-T78227

    5g
    46,00€
    10g
    80,00€
  • Mevociclib

    CAS :
    Mevociclib (SY-1365) is a highly selective covalent inhibitor of CDK7. SY-1365 possesses therapeutic potential in both hematological and solid tumors.
    Formule :C31H35ClN8O2
    Degré de pureté :98.02% - 98.02%
    Couleur et forme :Solid
    Masse moléculaire :587.11

    Ref: TM-T13044

    1mg
    180,00€
  • NU6300

    CAS :
    NU6300 is a covalent CDK2 inhibitor exhibiting irreversible and ATP-competitive properties and also functions as a GSDMD (Gasdermin D) inhibitor.
    Formule :C20H23N5O3S
    Degré de pureté :96.08%
    Couleur et forme :Solid
    Masse moléculaire :413.49

    Ref: TM-T16360

    5mg
    899,00€