Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(116 produits)
- CDK(547 produits)
- Arrêt du cycle cellulaire(5 produits)
- Chk(48 produits)
- DYRK(46 produits)
- Dynamine(27 produits)
- Ferroptose(233 produits)
- HSP(180 produits)
- Intégrine(276 produits)
- Kinésine(87 produits)
- LIM Kinase(21 produits)
- Microtubules associés(273 produits)
- PKC(128 produits)
- PLK(25 produits)
- ROCK(61 produits)
- Rho(6 produits)
- Wee1(14 produits)
- c-Myc(77 produits)
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3934 produits trouvés pour "Cycle cellulaire/point de contrôle"
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Pseudouridimycin
CAS :Pseudouridimycin: a C-nucleoside antibiotic, inhibits bacterial RNAP, targets Gram-negative and Gram-positive bacteria.Formule :C17H26N8O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :486.44CDK9-IN-25
CDK9-IN-25 (compound 4a), an imidazopyrazine derivative, functions as a CDK9 inhibitor with an IC50 of 0.24 μM.Formule :C15H16FN5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :285.32Endo-1,4-β-xylanase
CAS :Endo-1,4-β-xylanase (CtXyn11A) is a type of xylan hydrolase that hydrolyzes the β-1,4-glycosidic bond of the xylan molecule.Couleur et forme :SolidDNA Gyrase-IN-17
DNA Gyrase-IN-17 (Compound 5C) is an inhibitor of DNA gyrase. It demonstrates significant antimicrobial activity against a range of Gram-positive and Gram-negative strains, including Enterococcus faecium, Escherichia coli, and Pseudomonas aeruginosa, with a MIC value of 62.5 μg/mL. By inhibiting bacterial DNA gyrase, DNA Gyrase-IN-17 disrupts DNA replication. This compound can be useful in the development of antibiotics, particularly for studying resistant strains.Formule :C18H15ClFN5OCouleur et forme :SolidMasse moléculaire :371.09492HSDVHK-NH2
CAS :Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.Formule :C30H48N12O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :720.78HSDVHK-NH2 TFA
HSDVHK-NH2 TFA acts as an antagonist to the αvβ3-vitronectin integrin interaction, displaying an inhibitory concentration (IC 50) of 1.74 pg/mL (2.414 pM) [1] [Formule :C32H49F3N12O11Couleur et forme :SolidMasse moléculaire :834.85'-O-DMT-PAC-dA
CAS :5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].Formule :C39H37N5O7Couleur et forme :SolidMasse moléculaire :687.743'-Deoxyuridine-5'-triphosphate trisodium
3'-dUTP trisodium, a nucleotide analogue, inhibits RNA polymerases I/II and UTP integration into RNA (Ki=2.0 μM).Formule :C9H12N2Na3O14P3Couleur et forme :SoildMasse moléculaire :534.08GSK270822A
CAS :GSK270822A is a selective ROCK1 inhibitor. GSK270822A exhibits IC50 of 9nM, 1100nM, 1550nM for ROCK1, RSK1, p70S6K, respectively.Formule :C24H20N4O2Degré de pureté :98.64% - 99.78%Couleur et forme :SolidMasse moléculaire :396.44Ref: TM-T27467
1mg133,00€5mg314,00€1mL*10mM (DMSO)323,00€10mg416,00€25mg632,00€50mg847,00€100mg1.134,00€200mg1.513,00€Integrin Binding Peptide
CAS :Integrin Binding Peptide, derived from fibronectin, holds the potential as an essential component for preparing PEG hydrogels.Formule :C42H63N15O16SCouleur et forme :SolidMasse moléculaire :1066.12GSK299423
CAS :GSK299423: Antibiotic possibly effective against bacteria with New Delhi metal-β-lactamase, targeting topoisomerases.Formule :C25H27N5O2SDegré de pureté :97.34%Couleur et forme :SolidMasse moléculaire :461.583'-Deoxy-GTP trisodium
3'-Deoxy-GTP (3′-Deoxyguanosine 5′-triphosphate) trisodium, an analog of GTP, functions as an RNA chain terminator, thereby inhibiting RNA synthesis. It is capable of suppressing dengue virus DENV NS5 RdRp with an IC50 value of 0.02 μM.
Couleur et forme :Odour SolidGuanosine triphosphate
CAS :Guanosine triphosphate (GTP), a native nucleotide, and its derivatives may serve as specific inhibitors against COVID-19 [1].Formule :C10H16N5O14P3Couleur et forme :SolidMasse moléculaire :523.18CDK4/6-IN-23
CDK4/6-IN-23 (Compound 42) is a potent and selective inhibitor of CDK4/6, displaying an IC50 of 11 nM for CDK6. This compound significantly activates immune cells and enhances IL-3 production. In mice undergoing 5-FU chemotherapy, CDK4/6-IN-23 demonstrates dual bone marrow protection and immunomodulatory effects.Formule :C32H34FN7O4Couleur et forme :SolidMasse moléculaire :599.655Stigmatellin
CAS :Stigmatellin is an antibiotic derived from the cell mass of the myxobacterium, effective against yeasts (yeasts), filamentous fungi (filamentous fungi), and several Gram-positive bacteria (Gram-positive bacteria). Additionally, it serves as a potent inhibitor of photosynthetic electron (photosynthetic electron) transfer. Stigmatellin utilizes various sugars, polysaccharides, and acids from the citric acid cycle as substrates, inhibiting RNA and protein synthesis. It has two different inhibitory sites: one located on the reducing side of photosystem II and the other at the cytochrome b6/f complex. Stigmatellin holds potential for use in antimicrobial and photosynthesis research.Formule :C30H42O7Couleur et forme :SolidMasse moléculaire :514.655-Methylcytidine 5′-triphosphate trisodium
5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while
Formule :C10H15N3Na3O14P3Couleur et forme :SolidMasse moléculaire :563.13BSJ-03-204
CAS :BSJ-03-204 is a selective Cdk4/6 degrader.Formule :C43H48N10O8Couleur et forme :SolidMasse moléculaire :832.9Biotin-PEG7-C2-S-Vidarabine
Biotin-PEG7-C2-S-Vidarabine: PEG linker with antiviral adenosine analog effective against herpes and zoster.Formule :C36H60N8O12S2Couleur et forme :SolidMasse moléculaire :861.04Methylcarbamyl PAF C-8
Methylcarbamyl PAF C-8 is resistant to degradation by PAF-AH and has a half-life of over 100 minutes in platelet-poor plasma, exhibiting platelet aggregation activity. In NRK-49 cells overexpressing PAF receptor, it induces the expression of c-myc, c-fos, and activates mitogen-activated protein kinase (MAPK). Furthermore, Methylcarbamyl PAF C-8 can induce G1 phase cell cycle arrest. This compound shows potential for research in cardiovascular and anti-cancer applications.Couleur et forme :Odour SolidN3,5-Dimethyl-2'-O-(2-methoxyethyl) uridine
N3,5-Dimethyl-2’-O-(2-methoxyethyl) uridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Formule :C14H22N2O7Couleur et forme :SolidMasse moléculaire :330.33
