
Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(94 produits)
- CDK(500 produits)
- Arrêt du cycle cellulaire(4 produits)
- Chk(42 produits)
- DYRK(48 produits)
- Dynamine(23 produits)
- Ferroptose(215 produits)
- HSP(169 produits)
- Intégrine(224 produits)
- Kinésine(66 produits)
- LIM Kinase(19 produits)
- Microtubules associés(261 produits)
- PKC(102 produits)
- PLK(28 produits)
- ROCK(70 produits)
- Rho(2 produits)
- Wee1(15 produits)
- c-Myc(69 produits)
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3477 produits trouvés pour "Cycle cellulaire/point de contrôle"
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D-Xylofuranose, 1,2,3,5-tetraacetate
CAS :<p>1,2,3,5-Tetra-O-acetyl-D-xylofuranose is a starting material for the synthesis of nucleosides.</p>Formule :C13H18O9Couleur et forme :SolidMasse moléculaire :318.28Myt1-IN-1
CAS :<p>Myt1-IN-1 has anticancer effects that is a potent inhibitor of Myt1 with an IC 50 of <10 nM [1].</p>Formule :C16H15ClN4O2Couleur et forme :SolidMasse moléculaire :330.77AM-TS23
CAS :<p>AM-TS23 is used as a DNA polymerase lambda and beta inhibitor.</p>Formule :C17H12N2O3S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :388.48ML366
CAS :<p>ML366 is a Vibrio cholerae Quorum Sensing inhibitor Acting via the LuxO response regulator.</p>Formule :C17H19N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.35HBX28258
CAS :<p>HBX28258, a human USP7 inhibitor, binds covalently and selectively deactivates USP7 in colon cancer and kidney cells.</p>Formule :C26H30ClN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :435.99JNJ-9676
CAS :<p>JNJ-9676 is an orally active inhibitor of the coronavirus membrane protein, thereby blocking viral assembly and release.coronavirus and SARS-CoV.</p>Formule :C28H21F2N5O2Degré de pureté :99.83%Couleur et forme :SoildMasse moléculaire :497.5DHODH-IN-3
CAS :<p>DHODH-IN-3: Human DHODH inhibitor with IC50 of 261 nM, Kiapp 32 nM, potential anti-malaria drug.</p>Formule :C17H13ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :312.75OXA-06 Dihydrochloride
CAS :<p>OXA-06 Dihydrochloride is a PANC-1 cell migration and MYPT1 phosphorylation inhibitor.</p>Formule :C21H18FN3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :331.39Lysine-methotrexate
CAS :<p>Lysine-methotrexate is an anticancer drug. It is an inhibitor of dihydrofolate reductase.</p>Formule :C21H27N9O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :453.5Type II topoisomerase inhibitor 1
CAS :<p>Potent E. coli DNA gyrase inhibitor (IC50: 1.7 nM), targets Asp73; weak topoisomerase IV inhibitor (IC50: 0.98 μM).</p>Formule :C18H15N3O4Couleur et forme :SolidMasse moléculaire :337.33Ulecaciclib
CAS :<p>Ulecaciclib: oral, BBB-permeable CDK inhibitor; favorable pharmacokinetics; ki: 0.62 μM (CDK2/A), 3 nM (CDK6/D3), 0.2 nM (CDK4/D1), 0.63 μM (CDK7/H).</p>Formule :C25H33FN8SCouleur et forme :SolidMasse moléculaire :496.65LY 207702
CAS :<p>LY 207702, a difluorinated purine nucleoside, exhibits antitumor activity in preclinical models.</p>Formule :C10H12F2N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.24Codon readthrough inducer 1
CAS :<p>Codon readthrough inducer 1 contains pyrimidine bases and shows good readthrough activity.</p>Formule :C15H11N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :313.26MS0017509
CAS :<p>MS0017509 is a DNA damage repair inhibitor.</p>Formule :C11H10N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :198.22Cdc7-IN-13
CAS :<p>Cdc7-IN-13 (compound 84) is a highly potent CDC7 inhibitor, exhibiting an IC50 value of <1 nM. This compound holds promise for cancer research [1].</p>Formule :C18H20N4O2SCouleur et forme :SolidMasse moléculaire :356.44AZD7762 HCl
CAS :<p>AZD7762 HCl is a checkpoint kinase inhibitor, driving checkpoint abrogation and enhancing DNA-targeted treatment.</p>Formule :C17H20ClFN4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :398.882'-Fluorothymidine
CAS :<p>2'-Fluorothymidine is a selective substrate for TK2, related to thymidine and methyluridine.</p>Formule :C10H13FN2O5Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :260.22GR 144053 trihydrochloride
CAS :<p>platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist</p>Formule :C18H30Cl3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :454.82VPC-70619
CAS :<p>VPC-70619: Oral, selective N-Myc inhibitor; blocks cancer growth by hindering N-Myc-Max/DNA binding; well-absorbed.</p>Formule :C16H8ClF3N4OCouleur et forme :SolidMasse moléculaire :364.71Tetrahydrouridine
CAS :<p>Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator.</p>Formule :C9H16N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :248.23Cdc7-IN-9
CAS :<p>Cdc7-IN-9 can be used for the research of cancer which is a potent inhibitor of Cdc7 [1].</p>Formule :C15H17N5OSCouleur et forme :SolidMasse moléculaire :315.39CID 5951923
CAS :<p>CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.</p>Formule :C16H18N2O7SDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :382.39DAP-81
CAS :<p>DAP-81, a diaminopyrimidine, inhibits Plk1 (IC50: 0.9 nM), disrupts microtubules, causes monopolar spindles; in preclinical studies.</p>Formule :C25H20N6O4Couleur et forme :SolidMasse moléculaire :468.46CDK4/6-IN-9
CAS :<p>CDK4/6-IN-9 selectively inhibits CDK4/6 (IC50: 905 nM); potential for MM research.</p>Formule :C22H23FN8Couleur et forme :SolidMasse moléculaire :418.47HBV-IN-16
CAS :<p>HBV-IN-16, a quinoline derivative, inhibits HBV cccDNA, key for viral replication (from patent WO2019121357A1).</p>Formule :C22H20ClNO4Couleur et forme :SolidMasse moléculaire :397.85CDK7-IN-12
CAS :<p>CDK7-IN-12 inhibits CDK7 to control transcription and cell cycle, halting tumor growth in vitro/vivo with cancer research potential.</p>Formule :C20H19F3N6Couleur et forme :SolidMasse moléculaire :400.4Phelorphan
CAS :<p>Phelorphan is an inhibitor of enkephalinase.</p>Formule :C20H22N2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :386.46Crisnatol mesylate
CAS :<p>Crisnatol, a potent and selective DNA intercalator, has potential anticancer activity.</p>Formule :C24H27NO5SCouleur et forme :SolidMasse moléculaire :441.54BAY-958
CAS :<p>BAY-958 is a potent and selective inhibitor of PTEFb/CDK9.</p>Formule :C17H16FN5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :389.4Werner syndrome RecQ helicase-IN-3
CAS :<p>Potent WRN inhibitor, Werner syndrome RecQ helicase-IN-3, is orally active with 0.06 µM IC50; exhibits antiproliferative and anticancer effects.</p>Formule :C31H30ClF3N8O5Couleur et forme :SolidMasse moléculaire :687.07CFM-1
CAS :<p>CFM-1 is an antagonist of the anaphase-promoting complex (APC)-2. It also is a cell cycle and apoptosis regulatory protein (CARP)-1 interaction antagonist.</p>Formule :C12H7BrN2O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :355.23Mps-BAY2b
CAS :<p>Mps-BAY2b is a novel MPS1 inhibitor.</p>Formule :C20H23N5OCouleur et forme :SolidMasse moléculaire :349.43Indirubin-5-sulfonate
CAS :<p>Indirubin-5-sulfonate inhibits GSK-3β & CDKs with IC50: 55/35/150/300/65 nM for CDK1/B, 2/A&E, 4/D1, 5/p35.</p>Formule :C16H10N2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :342.33RUC-1
CAS :<p>RUC-1 is an αIIbβ3-selective ADP-induced platelet aggregation inhibitor.</p>Formule :C11H15N5OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :265.33Homocarbonyltopsentin
CAS :<p>Homocarbonyltopsentin: Small molecule, binds TSL2 pentaloops, enhances SMN2 E7 splicing, EC50 16 μM.</p>Formule :C21H14N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :370.36Guanoctine hydrochloride
CAS :<p>Guanoctine hydrochloride has antihypertensive activity.</p>Formule :C9H22ClN3Couleur et forme :SolidMasse moléculaire :207.74NSC 109555 ditosylate
CAS :<p>Chk2 inhibitor,ATP-competitive</p>Formule :C26H32N10O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :580.6614α-Demethylase/DNA Gyrase-IN-2
CAS :<p>14α-Demethylase/DNA Gyrase-IN-2 (Compound 6a) is a potent inhibitor of 14α-Demethylase/DNA Gyrase with antibacterial activity.</p>Formule :C24H22N4O4Couleur et forme :SolidMasse moléculaire :430.46BDM44768
CAS :<p>BDM44768 is an insulin-degrading enzyme (IDE) inhibitor that acts by inducing glucose intolerance.</p>Formule :C24H22FN5O3Couleur et forme :SolidMasse moléculaire :447.46IRE1α kinase-IN-3
CAS :<p>IRE1α kinase-IN-3 is a potent, ATP-competitive inhibitor of IRE1α (Ki: 480 nM).</p>Formule :C29H32N6O3SCouleur et forme :SolidMasse moléculaire :544.67Mps1-IN-4
CAS :<p>Mps1-IN-4 is a compound that selectively inhibits Monopolar spindle 1 (Mps1), exhibiting antiproliferative properties useful in cancer research.</p>Formule :C26H31F3N6O2Couleur et forme :SolidMasse moléculaire :516.56CDK7-IN-8
CAS :<p>CDK7-IN-8 is a potent inhibitor of CDK7 (IC50: 54.29 nM) and exhibits inhibitory activity against several cancer cells and in vivo tumor models.</p>Formule :C25H38N8O3Couleur et forme :SolidMasse moléculaire :498.62Nucleoside-Analog-2
CAS :<p>Nucleoside-Analog-2 is a 4'-Azidocytidine analogue, used to against Hepatitis C virus (HCV) replication.</p>Formule :C9H11N5O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :285.212'-Deoxy-L-guanosine
CAS :<p>2'-Deoxy-L-guanosine is a nucleoside that shows antibiotic properties by inhibiting protein synthesis, leading to cell death.</p>Formule :C10H13N5O4Couleur et forme :SolidMasse moléculaire :267.24VE-465
CAS :<p>VE-465 is an inhibitor of Aurora kinase, which involves in multiple mitotic events.</p>Formule :C22H28N8OSCouleur et forme :SolidMasse moléculaire :452.58Antitumor agent-85
<p>Antitumor agent-85 stabilizes G4-DNA with potent anti-tumor effects.</p>Formule :C24H33N7Couleur et forme :SolidMasse moléculaire :419.57XU1
CAS :<p>XU1(Benzo[c][1,8]naphthyridin-6(5h)-One) is an Aurora protein kinase inhibitor used for the treatment of diseases suitable for inhibition, regulation or</p>Formule :C12H8N2ODegré de pureté :98.58% - 99.59%Couleur et forme :SolidMasse moléculaire :196.2HBV-IN-15
CAS :<p>HBV-IN-15, a flavone derivative, is a potent cccDNA inhibitor, potentially aiding HBV research.</p>Formule :C24H23ClO6Couleur et forme :SolidMasse moléculaire :442.89PD-1-IN-22
CAS :<p>PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).</p>Formule :C25H25N5O4Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :459.5TC-Mps1-12
CAS :<p>TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .</p>Formule :C17H20N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.38CB 3717
CAS :<p>CB 3717 is an enzyme inhibitor, antineoplastic agent, folic acid antagonist.</p>Formule :C24H23N5O6Couleur et forme :SolidMasse moléculaire :477.47Pyrazofurin
CAS :<p>Pyrazofurin, a pyrimidine analogue, blocks cell growth and DNA synthesis by targeting UMP synthase & orotate-phosphoribosyltransferase (IC50: 0.06-0.37 μM).</p>Formule :C9H13N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :259.22IPR-803
CAS :<p>IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity.</p>Formule :C27H23N3O4Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :453.49Datelliptium chloride
CAS :<p>Datelliptium chloride is a DNA-intercalating agent derived from ellipticine. Datelliptium chloride shows anti-tumor activities.</p>Formule :C23H28ClN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :397.94Sibrafiban
CAS :<p>Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.</p>Formule :C20H28N4O6Couleur et forme :SolidMasse moléculaire :420.46CFI-400437
CAS :<p>CFI-400437 is an ATP-competitive PLK4 inhibitor (IC50: 0.6 nM) and is an indolequinone derivative.</p>Formule :C29H28N6O2Couleur et forme :SolidMasse moléculaire :492.57IACS-4759
CAS :<p>IACS-4759 is a novel potent and selective MTH1 inhibitor with excellent cell permeability and good metabolic stability in microsomes.</p>Formule :C10H17N3O2Couleur et forme :SolidMasse moléculaire :211.26FINDY
CAS :<p>FINDY selectively inhibits DYRK1A at 35 μM IC50, blocking Ser97 autophosphorylation, useful for neurological disorder research.</p>Formule :C16H17NO2S2SiCouleur et forme :SolidMasse moléculaire :347.53CDK-IN-10
CAS :<p>CDK-IN-10 is a cell cycle protein-dependent kinase (CDK) inhibitor with potential anticancer activity for cancer research.</p>Formule :C18H18N4O2Degré de pureté :97.07%Couleur et forme :SolidMasse moléculaire :322.36SR7826
CAS :<p>SR7826 is a selective LIMK inhibitor.</p>Formule :C22H21N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.43MtTMPK-IN-6
CAS :<p>MtTMPK-IN-6 inhibits M. tuberculosis thymidylate kinase with IC50 of 29 μM, promising for TB research.</p>Formule :C23H25N3O3Couleur et forme :SolidMasse moléculaire :391.46ERCC1-XPF-IN-1
CAS :<p>ERCC1-XPF-IN-1: potent ERCC1-XPF inhibitor (IC50: 0.49 μM), hampers CPD removal, boosts UV toxicity, hinders DNA repair.</p>Formule :C28H32ClN5O2Couleur et forme :SolidMasse moléculaire :506.04CLT-28643
CAS :<p>CLT-28643 is a specific α5β1-Integrin inhibitor that prevents fibrosis in GFS, inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation.</p>Formule :C19H17N3O4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :351.36ML372
CAS :<p>ML372 is a potent and selective SMN Modulator (EC50 = 12 nM, 325% increase inSMN2) with good potency, pharmacokinetics, tolerance, and CNS penetration.</p>Formule :C18H20N2O4SCouleur et forme :SolidMasse moléculaire :360.43BMS-587101
CAS :<p>BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.</p>Formule :C26H20Cl2N4O4SCouleur et forme :SolidMasse moléculaire :555.43PFM03
CAS :<p>PFM03 is a endonuclease inhibitor that specifically blocks Mre11,reduce MRN endonuclease activity, blocking hMRN-mediated endonucleotomy and nuclear exocytosis.</p>Formule :C14H15NO2S2Degré de pureté :99.81% - 99.98%Couleur et forme :SolidMasse moléculaire :293.4c-Myc inhibitor 9
CAS :<p>c-Myc inhibitor 9 (compound 332) with logEC50 ≥6, suppresses tumors in mice, useful for cancer research.</p>Formule :C27H31N5OSCouleur et forme :SolidMasse moléculaire :473.63CDK7-IN-20
<p>CDK7-IN-20: potent, irreversible CDK7 inhibitor, IC50 of 4nM, 206x selectivity vs. other CDKs, potential for ADPKD study.</p>Formule :C30H26N6O3Couleur et forme :SolidMasse moléculaire :518.57Integrin modulator 1
CAS :<p>Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.</p>Formule :C13H14N2O4Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :262.26EMD534085
CAS :<p>EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).</p>Formule :C25H31F3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :476.53Chrysotobibenzyl
CAS :<p>Chrysotobibenzyl from Dendrobium pulchellum stems may trigger cell death in detached cells and hinder lung cancer growth.</p>Formule :C19H24O5Couleur et forme :SolidMasse moléculaire :332.39XMD-17-51
CAS :<p>XMD-17-51 has DCLK1 kinase inhibitory activity, inhibits DCLK1 and cell proliferation, and can be used in lung cancer research.</p>Formule :C21H24N8ODegré de pureté :99.04%Couleur et forme :SoildMasse moléculaire :404.478RK64
CAS :<p>8RK64 is a covalent UCHL1 inhibitor ( IC 50 : 0.32 μM) .</p>Formule :C14H16N8O2SCouleur et forme :SolidMasse moléculaire :360.45,10-Dideazafolic acid
CAS :<p>5,10-Dideazafolic acid is an antileukemic drug.</p>Formule :C21H21N5O6Couleur et forme :SolidMasse moléculaire :439.42CDK7-IN-13
CAS :<p>CDK7-IN-13: A potent pyrimidine-based CDK7 inhibitor, potential for various cancers. See CN114249712A.</p>Formule :C20H23F3N6OSDegré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :452.5Indirubin-3'-monoxime-5-sulphonic acid
CAS :<p>Indirubin-3'-monoxime-5-sulphonic acid is a potent and selective inhibitor of GSK-3β, CDK5, and CDK1 with IC50s of 80nM,5 nM, and 7 nM, respectively.</p>Formule :C16H11N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :357.3410-Deazaaminopterin
CAS :<p>10-Deazaaminopterin is a poly-gamma-glutamyl metabolite of the experimental anticancer drug, a folic acid antagonist, antineoplastic agent enzyme inhibitor.</p>Formule :C20H21N7O5Couleur et forme :SolidMasse moléculaire :439.42Antibacterial agent 89
CAS :<p>Antibacterial agent 89 blocks bacterial transcription and clostridial cytotoxins, inhibiting β'CH-σ interactions.</p>Formule :C21H10Cl2F3NO5SCouleur et forme :SolidMasse moléculaire :516.27P1788
CAS :<p>P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor that can induce DNA damage [1].</p>Formule :C15H17NO3Couleur et forme :SolidMasse moléculaire :259.3Cdc7-IN-7c
CAS :<p>Cdc7-IN-7c (Cdc7 inhibitor-7c) has antitumor activity and has inhibitory effect on liver cancer, lung cancer, kidney cancer, brain cancer and cervical cancer.</p>Formule :C15H17N5OSDegré de pureté :98.19% - 99.22%Couleur et forme :SolidMasse moléculaire :315.39AS-0141
CAS :<p>AS-0141 (Cdc7-IN-6) 是一种有效的 Cdc7 激酶抑制剂 (IC50=4 nM),具有抗肿瘤活性。Cdc7 是一种丝氨酸苏氨酸蛋白激酶酶,在细胞周期中对 DNA 复制的启动至关重要。</p>Formule :C21H22F3N5O4Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :465.43Anticancer agent 73
CAS :<p>Anticancer agent 73 inhibits TRBP, disrupting TRBP-Dicer, and hinders HCC growth and spread by altering HCC miRNA and protein expression.</p>Formule :C14H15NO4Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :261.27AzddMeC
CAS :<p>AzddMeC (Az-Dcme) is an HIV-1 reverse transcriptase and HIV-1 replication inhibitor with antiretroviral activity.AzddMeC is used in the study of HIV-1 infection</p>Formule :C10H14N6O3Degré de pureté :97.14% - 99.62%Couleur et forme :SolidMasse moléculaire :266.26ITX3
CAS :<p>ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM.</p>Formule :C22H17N3OSDegré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :371.45Firategrast
CAS :<p>Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous</p>Formule :C27H27F2NO6Degré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :499.5116-9e
CAS :<p>116-9e (MAL2-11B) is an Hsp70 chaperone DNAJA1 inhibitor with antiviral properties, inhibits SV40 replication, and can be used to study cancer drug resistance.</p>Formule :C31H32N2O5Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :512.6D-I03
CAS :<p>D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM.</p>Formule :C23H36N6SDegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :428.64CF-1743
CAS :<p>CF-1743 is an anti-varicella zoster virus nucleoside and inhibits VZV replication.</p>Formule :C22H26N2O5Degré de pureté :99.6% - 99.79%Couleur et forme :SolidMasse moléculaire :398.45Abemaciclib metabolite M20
CAS :<p>Abemaciclib metabolite M20 (CDK4/6-IN-4) 是 Abemaciclib 的活性代谢物。 Abemaciclib metabolite M20 是一种特异性 CDK4/6 抑制剂,可用于癌症治疗的相关研究。</p>Formule :C27H32F2N8ODegré de pureté :98.1% - 99.08%Couleur et forme :SolidMasse moléculaire :522.59hDHODH-IN-7
CAS :<p>hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor.</p>Formule :C21H23FN4ODegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :366.43DS18561882
CAS :<p>DS18561882: Potent MTHFD2 inhibitor (IC50=0.0063), inhibits MTHFD1 (IC50=0.57), good oral kinetics.</p>Formule :C28H31F3N4O6SDegré de pureté :98.19% - >99.99%Couleur et forme :SolidMasse moléculaire :608.63CD532
CAS :<p>CD532: Potent Aurora A inhibitor, IC50=45 nM, blocks kinase activity, degrades MYCN, interacts with AURKA, studies cancer.</p>Formule :C26H25F3N8ODegré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :522.52GKI-1
CAS :<p>GKI-1, a GWL kinase inhibitor: IC50 - 4.9 µM for hGWLFL, 2.5 µM for hGWL-KinDom, 11 µM for ROCK1; weak on PKA.</p>Formule :C15H12ClN3Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :269.73Elarofiban
CAS :<p>Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.</p>Formule :C22H32N4O4Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :416.51CDK9-IN-10
CAS :<p>CDK9-IN-10 is a potent CDK9 inhibitor and the ligand for the PROTAC CDK9 degrader-2.</p>Formule :C22H16O5Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :360.36Galocitabine
CAS :<p>Galocitabine (Neofrutulon), a thymidylate synthase inhibitor, is used potentially for the treatment of cancer.</p>Formule :C19H22FN3O8Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :439.39Caracemide
CAS :<p>Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.</p>Formule :C6H11N3O4Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :189.176RK73
CAS :<p>6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 µM). 6RK73 shows almost no inhibition of UCHL3 (IC50: 236 µM).</p>Formule :C13H17N5O2SDegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :307.37GS-6620 PM
CAS :<p>GS-6620 PM, oral Hep C polymerase inhibitor prodrug, is a potent GS-6620 derivative with limited activity against other viruses.</p>Formule :C13H15N5O4Degré de pureté :98.52% - 98.7%Couleur et forme :SolidMasse moléculaire :305.29CHK1-IN-3
CAS :<p>CHK1-IN-3 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 0.4 nM).</p>Formule :C20H23N9ODegré de pureté :98.78%Couleur et forme :SolidMasse moléculaire :405.4610-Formylfolic acid
CAS :<p>10-Formylfolic acid is a novel and potent inhibitor of dihydrofolate reductase, which can be used in leukemia research.</p>Formule :C20H19N7O7Degré de pureté :98.42%Couleur et forme :SolidMasse moléculaire :469.419-Isopropylolomoucine
CAS :<p>9-Isopropylolomoucine (N9-Isopropylolomoucine), a cell cycle protein-dependent kinase inhibitor, is a thiopurine.</p>Formule :C17H22N6ODegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :326.4TC-S 7005
CAS :<p>TC-S 7005 is an effective inhibitor of Polo-like kinases (IC50s: 214 nM, 4 nM and 24 nM for Plk1, Plk2, and Plk3).</p>Formule :C21H17N3O3Degré de pureté :99.516%Couleur et forme :SolidMasse moléculaire :359.38CRT-0105950
CAS :<p>CRT-0105950 is an effective LIMK inhibitor that acts by suppressing cofilin phosphorylation and increasing αTubulin acetylation in cells.</p>Formule :C21H16ClN3OSDegré de pureté :99.78% - 99.86%Couleur et forme :SolidMasse moléculaire :393.89CDK8-IN-1
CAS :<p>CDK8-IN-1 is a selective CDK8 inhibitor (IC50: 3 nM).</p>Formule :C11H8F3N3ODegré de pureté :98.48%Couleur et forme :SolidMasse moléculaire :255.2AGX51
CAS :<p>AGX51 is an antagonist of inhibitor of DNA binding (ID) proteins. AGX51 treatment lead to pan-Id degradation, cell cycle arrest, and cell death.</p>Formule :C27H29NO4Degré de pureté :97.65%Couleur et forme :OilMasse moléculaire :431.52Peldesine
CAS :<p>Peldesine (BCX 34), an oral purine nucleoside phosphorylase blocker, halts T-cell growth; used in CTCL, psoriasis, HIV research. IC50: 800 nM.</p>Formule :C12H11N5ODegré de pureté :99.27% - 99.9%Couleur et forme :SolidMasse moléculaire :241.256-Hydroxy-DOPA
CAS :<p>6-Hydroxy-DOPA is an allosteric inhibitor of RAD52, it inhibits proliferation of BRCA-deficient cancer cells in vitro and also inhibits APE1.</p>Formule :C9H11NO5Degré de pureté :97.78% - 97.95%Couleur et forme :SolidMasse moléculaire :213.19NR2F6 modulator-1
CAS :<p>NR2F6 modulator-1, a potent agent for NR2F6, affects immune response and tumor stem cell activity.</p>Formule :C23H17NO5SDegré de pureté :98.31%Couleur et forme :SolidMasse moléculaire :419.45Chiauranib
CAS :<p>Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.</p>Formule :C27H21N3O3Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :435.47Cytembena
CAS :<p>Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.</p>Formule :C11H8BrNaO4Degré de pureté :99.35%Couleur et forme :White PowderMasse moléculaire :307.07Talviraline
CAS :<p>Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in a</p>Formule :C15H20N2O3S2Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :340.46HA-1004
CAS :<p>HA-1004 is a inhibitor of PKG, PKA, PKC and MLC.</p>Formule :C12H15N5O2SDegré de pureté :99.56% - 99.63%Couleur et forme :SolidMasse moléculaire :293.34dCeMM2
CAS :<p>dCeMM2 degrades glue by promoting CDK12-cyclin K ubiquitination and degradation via CRL4B ligase interaction.</p>Formule :C16H11ClN6OSDegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :370.82TTP-8307
CAS :<p>TTP-8307 is an antiviral compound that inhibits the replication of rhinoviruses and enteroviruses and is used in the study of viral infections.</p>Formule :C27H21FN4ODegré de pureté :98.95%Couleur et forme :SolidMasse moléculaire :436.48BioE-1115
CAS :<p>BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM).</p>Formule :C19H18FN3O2Degré de pureté :97.54%Couleur et forme :SolidMasse moléculaire :339.36CHD1Li 6.11
CAS :<p>CHD1Li 6.11 inhibits CHD1L protein (IC50: 3.3 µM), shrinks CRC tumors in vivo, and is orally active.</p>Formule :C21H22BrN5OSDegré de pureté :99.04%Couleur et forme :SolidMasse moléculaire :472.4(S)-PF-06873600
CAS :<p>(S)-PF-06873600 is the S enantiomer of PF-06873600 which is an inhibitor of CDK.</p>Formule :C20H27F2N5O4SDegré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :471.52Haspin-IN-3
CAS :<p>Haspin-IN-3 is a potent haspin inhibitor with an IC50 of 14 nM.Haspin-IN-3 has anticancer activity.</p>Formule :C16H10N2O3Degré de pureté :98.78%Couleur et forme :SolidMasse moléculaire :278.26Ryuvidine
CAS :<p>Ryuvidine is a dual inhibitor of KDM5A and SETD8, an inducer of the DNA damage response, and can be used to study breast cancer and erythroderma.</p>Formule :C15H12N2O2SDegré de pureté :98.6%Couleur et forme :SolidMasse moléculaire :284.33GRK6-IN-1
CAS :<p>GRK6-IN-1 (compound 18) is a potent GRK6 blocker, with an IC50 of 120 nM, showing promise for multiple myeloma research.</p>Formule :C22H23ClN6O2Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :438.91UMK57
CAS :<p>UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds,</p>Formule :C17H17N3SDegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :295.4Eprociclovir
CAS :<p>Eprociclovir (A-5021) is a novel acyclovir analog that is a potent inhibitor of EHV1 replication and may be used for the treatment and/or prevention of</p>Formule :C11H15N5O3Degré de pureté :98.50% - 99.86%Couleur et forme :SolidMasse moléculaire :265.27CDK4/6/1 Inhibitor
CAS :<p>CDK4/6/1 Inhibitor (Crozbaciclib) is a type of CDK4/6 inhibitor (IC50s: 3 and 1 nM).</p>Formule :C28H30F2N6Degré de pureté :99.26% - 99.72%Couleur et forme :SolidMasse moléculaire :488.57hSMG-1 inhibitor 11e
CAS :<p>hSMG-1 inhibitor 11e is an effective and selective inhibitor of hSMG-1 (IC50 <0.05 nM) and can be used in studies about cancer treatment.</p>Formule :C26H27N7O3SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :517.6BML-259
CAS :<p>BML-259 inhibits CDK5/CDK2 (IC50: 64/98 nM) for cancer and neurodegeneration research.</p>Formule :C14H16N2OSDegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :260.35SB-747651A Dihydrochloride
CAS :<p>SB-747651A dihydrochloride, an MSK1 inhibitor (IC50=11 nM), also targets PRK2, RSK1, p70S6K, ROCK-II; potential in inflammation study.</p>Formule :C16H24Cl2N8ODegré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :415.32RP-6306
CAS :<p>Lunresertib (RP-6306) is a potent, selective, and orally active PKMYT1 inhibitor with an IC50 of 14 nM.Cost-effective and quality-assured.</p>Formule :C18H20N4O2Degré de pureté :98.41% - 99.28%Couleur et forme :SolidMasse moléculaire :324.38SEL120-34A
CAS :<p>SEL120-34A inhibits CDK8 (IC50: 4.4 nM) & CDK19 (10.4 nM), less on CDK9 (1070 nM), has antitumor properties.</p>Formule :C15H18Br2N4Degré de pureté :99.764% - 99.84%Couleur et forme :SolidMasse moléculaire :414.14CDK-IN-2
CAS :<p>CDK-IN-2 (CDK inhibitor II) is a potent and specific CDK9 inhibitor (IC50: <8 nM).</p>Formule :C18H19ClFN3O2Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :363.81DDRI-18
CAS :<p>DDRI-18 is an inhibitor that regulates the DNA damage response, has anticancer activity, and inhibits non-homologous end-joining (NHEJ) DNA repair.</p>Formule :C26H20N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :416.48ZIM
CAS :<p>ZIM, from 4-Aminoantipyrine, induces DNA and chromosomal damage, cell death, and phagocytosis, with potential in cancer therapy.</p>Formule :C20H19N3O3Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :349.38Cdk2 Inhibitor II
CAS :<p>Cdk2 Inhibitor II is a selective and potent CDK2 inhibitor50 at 60 nM.</p>Formule :C14H11BrN4O3SDegré de pureté :97.07%Couleur et forme :SolidMasse moléculaire :395.23Talotrexin ammonium
CAS :<p>Talotrexin ammonium, a non-polyglutamic antifolate, inhibits cancer by targeting DHFR.</p>Formule :C27H30N10O6Degré de pureté :97.49%Couleur et forme :SolidMasse moléculaire :590.59NSC16168
CAS :<p>NSC16168 is a selective ERCC1-XPF inhibitor that inhibits DNA repair and potentiates the antitumor activity of cisplatin.</p>Formule :C17H15NO9S3Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :473.5PS423
CAS :<p>PS423 is a substrate-selective protein kinase PDK1 inhibitor that acts by binding to the PIF-pocket allosteric docking site.</p>Formule :C25H23F3O9Degré de pureté :98.81% - 99.26%Couleur et forme :SolidMasse moléculaire :524.44ERCC1-XPF-IN-2
CAS :<p>ERCC1-XPF-IN-2: Nucleotide repair active, boosts cisplatin, inhibits ERCC1-XPF (IC50: 0.6 μM).</p>Formule :C15H13Cl2NO3Degré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :326.17(S)-Enitociclib
CAS :<p>(S)-Enitociclib (VIP152) is a selective CDK9 inhibitor that inhibits the transcription of anti-apoptotic and pro-survival proteins.</p>Formule :C19H18F2N4O2SDegré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :404.43SMN-C2
CAS :<p>SMN-C2, a SMN2 gene splicing regulator, is an RNA-binding ligand that regulates pre-mRNA splicing and has potential for studying spinal muscular atrophy.</p>Formule :C24H27N5O2Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :417.5Netivudine
CAS :<p>Netivudine, a potent NRTI with anti-varicella activity, treats HIV by inhibiting reverse transcriptase, reducing viral load.</p>Formule :C12H14N2O6Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :282.25Poloxin-2
CAS :<p>Poloxin-2 is a potent and selective Plk1 PBD inhibitor with anti-tumour activity that reduces the protein level of Plk1 in HeLa cells.</p>Formule :C16H15NO3Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :269.3PCSK9-IN-10
CAS :<p>PCSK9-IN-10: potent oral PCSK9 inhibitor (IC50 = 6.4 µM), upregulates LDLR, curbs atherosclerosis, for hyperlipidemia research.</p>Formule :C18H23N5O4Degré de pureté :99.06%Couleur et forme :SoildMasse moléculaire :373.41COH34
CAS :<p>COH34 (1-[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol) is a selective inhibitor of PARG with an IC50 of 0.37 nM and a Kd of 0.547 μM.</p>Formule :C18H15NOSDegré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :293.38L82
CAS :<p>L82: A selective, non-competitive DNA Lig1 inhibitor with anti-proliferative effects on breast cancer cells. IC50=12 μM.</p>Formule :C11H8ClN5O4Degré de pureté :97.45% - 98.91%Couleur et forme :SolidMasse moléculaire :309.67RP-6685
CAS :<p>RP-6685 is a potent, selective DNA Polθ inhibitor with strong oral efficacy, an IC50 of 5.8 nM, and marked antitumor effects in mice.</p>Formule :C22H14F7N5ODegré de pureté :99.65%Couleur et forme :SoildMasse moléculaire :497.37SB 328437
CAS :<p>SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).</p>Formule :C21H18N2O5Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :378.38DENV-IN-5
CAS :<p>Denv-in-5 is an effective and selective dengue virus (DENV) inhibitor with EC50 values of 1.47, 9.23, 7.08, 8.91 μM for denV-I-IV and 0.1512 μM for HIV-1IIIB.</p>Formule :C23H25ClF2N4OSDegré de pureté :99.06%Couleur et forme :SolidMasse moléculaire :478.99CDK-IN-11
CAS :<p>CDK-IN-11, a heterocyclic compound, promotes cardiomyocyte maturation [1].</p>Formule :C25H21BrN4O2Couleur et forme :SolidMasse moléculaire :489.36WRN inhibitor 3
CAS :<p>WRN Inhibitor 3 (example 110), a cyclic vinyl sulfone-based compound, serves as an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN).</p>Formule :C20H20N2O5SCouleur et forme :SolidMasse moléculaire :400.45WRN inhibitor 4
CAS :<p>WRN Inhibitor 4 (Example 107), a cyclic vinyl sulfone-based compound, serves as an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN).</p>Formule :C16H14N2O5SCouleur et forme :SolidMasse moléculaire :346.36QR-6401
CAS :<p>QR-6401, a selective macrocyclic CDK2 inhibitor, is orally active with IC50 values of 0.37 nM for CDK2/E1, 10 nM for CDK9/T1, 22 nM for CDK1/A2, 34 nM for CDK6/</p>Formule :C19H23N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :369.42CDK9-IN-8
CAS :<p>CDK9-IN-8 is a highly potent and selective CDK9 inhibitor (IC50: 12 nM).</p>Formule :C31H32FN7O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :569.63G4/HDAC-IN-1
<p>G4/HDAC-IN-1, a G4/HDAC dual inhibitor, IC50 1.1 µM, blocks TNBC growth, useful in cancer research.</p>Formule :C36H49ClFN7O4Couleur et forme :SolidMasse moléculaire :698.27CDK9-IN-29
CAS :<p>CDK9-IN-29 (compound Z11) is a potent inhibitor of CDK9, exhibiting high kinase selectivity and an IC50 value of 3.20 nM.</p>Formule :C29H33F2N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :553.6CDK/HDAC-IN-3
CAS :<p>CDK/HDAC-IN-3 is an orally active dual inhibitor of HDACs and CDKs, offering potent and selective inhibition of CDK9, CDK12, CDK13, HDAC1, HDAC2, and HDAC3,</p>Formule :C24H18Cl2N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :509.34c-Myc inhibitor 8
CAS :<p>c-Myc inhibitor 8 suppresses cell growth in various cancers and is used in research.</p>Formule :C19H12BrClF3NO3S2Couleur et forme :SolidMasse moléculaire :538.79Sapacitabine
CAS :<p>Sapacitabine (CS682) is a nucleoside analog precursor with anticancer activity used in the study of leukemia.</p>Formule :C26H42N4O5Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :490.64Nε-(1-Carboxyethyl)-L-lysine
CAS :<p>Nε-(1-Carboxyethyl)-L-lysine (CEL) is an advanced glycation end-product (AGE). Exposure to CEL reduces glutamate uptake and S100B secretion in the hippocampus.</p>Formule :C9H18N2O4Couleur et forme :SolidMasse moléculaire :218.25BVDU 5′-Triphosphate
CAS :<p>BVDU 5′-Triphosphate is an antiviral agent labeled with 5′-Triphosphate that specifically targets viral DNA polymerase.</p>Formule :C11H16BrN2O14P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :573.08GGTI 2147
CAS :<p>GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.</p>Formule :C28H30N4O3Degré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :470.565'-ODMT cEt m5U Phosphoramidite (Amidite)
CAS :<p>5'-ODMT cEt m5U Phosphoramidite Amidite, a locked nucleic acid (LNA) analog, demonstrates exceptional safety and antisense activity [1] [2].</p>Formule :C42H51N4O9PCouleur et forme :SolidMasse moléculaire :786.859-Deazaguanine
CAS :<p>9-Deazaguanine is a nucleoside analogue exhibiting inhibitory activity against bovine purine nucleoside phosphorylase (PNP).</p>Formule :C6H6N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :150.148-Azahypoxanthine
CAS :<p>8-Azahypoxanthine (NSC-22709) inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.</p>Formule :C4H3N5ODegré de pureté :99.66%Couleur et forme :Light Yellow To Light Beige Fine CrystallineMasse moléculaire :137.1ATN-161
CAS :<p>ATN-161 is an integrin α5β1 binding peptide and antagonist that inhibits VEGF-induced hCECs migration and angiogenesis.</p>Formule :C23H35N9O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :597.64Raluridine
CAS :<p>Raluridine is an HIV treatment inhibiting RNA-directed DNA polymerase with IC50 of 1.8 microM, compared to FLT, AZT, ddI, and ddC.</p>Formule :C9H10ClFN2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :264.64(2S,3R)-Voruciclib
CAS :<p>(2S,3R)-Voruciclib is the (2S,3R)-enantiomer of Voruciclib. It is an orally active CDK inhibitor.</p>Formule :C22H19ClF3NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :469.84TC-I 15
CAS :<p>α2β1 integrin inhibitor</p>Formule :C23H28N4O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :520.62αvβ1 integrin-IN-2
CAS :<p>αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively.</p>Formule :C29H38N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.64α7β1 integrin modulator-1
CAS :<p>α7β1 Integrin Modulator-1 is a potent modulator with research potential for muscular dystrophy [1].</p>Formule :C23H29N3O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :475.56DAM-IN-1
CAS :<p>DMA-IN-1 is a DNA adenine methyltransferase (DAM) inhibitor with an IC50 value of 48 μM.</p>Formule :C16H17NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :287.31CT1113
CAS :<p>CT1113, a potent inhibitor of both USP28 and USP25, effectively reduces MYC levels in vivo and demonstrates anti-tumor efficacy in a mouse pancreatic cancer CDX</p>Formule :C25H29N5O2SCouleur et forme :SolidMasse moléculaire :463.6Votoplam
CAS :<p>Votoplam functions as a gene splicing modulator, employed in the inhibition of Huntington's disease [1].</p>Formule :C21H25N9ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.48NITD008
CAS :<p>NITD008 (7-Deaza-2'-C-acetylene-adenosine) is an adenosine nucleoside inhibitor with antiviral activity that inhibits dengue and Zika viruses.</p>Formule :C13H14N4O4Degré de pureté :98.04%Couleur et forme :SolidMasse moléculaire :290.27Aurora Kinases-IN-4
CAS :<p>Aurora Kinases-IN-4 (Compound 11c) is a covalent, ATP-competitive inhibitor of aurora kinase A with an IC50 value of 1.7 nM.</p>Formule :C26H28N8ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.55G-5758
CAS :<p>G-5758 is an orally active IRE1α inhibitor with an IC50 of 38 nM for XBP1s. It is used in studies involving multiple myeloma models [KMS-11], demonstrating good tolerance in rats at oral doses up to 500 mg/kg. G-5758 exhibits pharmacodynamic effects comparable to those induced by IRE1 knockdown.</p>Formule :C27H24F4N6O3SCouleur et forme :SolidMasse moléculaire :588.58ON 108600
CAS :<p>ON 108600 is a chemical inhibitor targeting CK2 (Casein Kinase 2), TNIK, and DYRK1, demonstrating IC50 values of 0.016 μM and 0.007 μM for DYRK1A and DYRK1B, 0.</p>Formule :C22H14Cl2N2O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :537.392'-Deoxypseudoisocytidine
CAS :<p>2'-Deoxypseudoisocytidine is a nucleoside analogue.</p>Formule :C9H13N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :227.22ROCK2-IN-7
CAS :<p>ROCK2 inhibitor is a chemical compound associated with the therapeutic management of psoriasis.</p>Formule :C26H28FN5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :445.53PD-1/PD-L1-IN-34
CAS :<p>PD-1/PD-L1-IN-34 (Compound (1S,2S)-A25) effectively inhibits the PD-1/PD-L1 interaction (IC 50 = 0.029 μM) and demonstrates selective binding affinity to PD-L1</p>Formule :C35H33ClN2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :565.1SZ-015268
CAS :<p>SZ-015268: CDK7 inhibitor, IC50=23.56 nM; hinders HCC70, OVCAR-3, HCT116, HCC1806 cell growth; strong anti-tumor effect.</p>Formule :C25H38N8O3Couleur et forme :SolidMasse moléculaire :498.62ASC-69
CAS :<p>ASC-69 (APY69) is a promising potent inhibitor of the PD-1/PD-L1 signaling pathway, classified as a small-molecule compound [1].</p>Formule :C19H19N7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :345.4ML-099
CAS :<p>ML-099 is a pan Ras-related GTPases activator that activates Rac1, Ras, GTP-binding protein (Rab7), Rab2A and cell division cycle 42.</p>Formule :C14H13NO2SDegré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :259.32Alatrofloxacin
CAS :<p>Alatrofloxacin is a prodrug of trovafloxacin.</p>Formule :C26H25F3N6O5Couleur et forme :SolidMasse moléculaire :558.51L-739758
CAS :<p>L-739758 is a glycoprotein IIb/IIIa inhibitor.</p>Formule :C22H26N4O5S3Couleur et forme :SolidMasse moléculaire :522.66CCT-271850
CAS :<p>CCT-271850 is an inhibitor of the spindle checkpoint function of Monospindle 1.</p>Formule :C24H29N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :431.53Palbociclib orotate
CAS :<p>Palbociclib (PD 0332991) orotate, an orally active selective inhibitor of CDK4 and CDK6, exhibits IC50 values of 11 and 16 nM, respectively.</p>Formule :C29H33N9O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :603.63Lerociclib
CAS :<p>Lerociclib (G1T38) is a CDK4/6 inhibitor with anticancer and antitumor activities, inhibiting CDK4/CyclinD1 and CDK6/CyclinD3.</p>Formule :C26H34N8ODegré de pureté :99%Couleur et forme :SolidMasse moléculaire :474.6UNC2170 maleate
CAS :<p>53BP1-binding protein 1 (53BP1) engages with dimethylated lysine 20 on histone 4 (H4K20me2) through its tandem tudor domains within a homodimer configuration, crucial for the DNA damage response. UNC2170, a micromolar 53BP1 ligand, selectively interacts with this site, demonstrating at least 17-fold preference for 53BP1 over similar proteins. This interaction occurs in a pocket formed by the 53BP1's tudor domains. Moreover, UNC2170 acts as an antagonist to 53BP1 in cellular lysates, effectively inhibiting class switch recombination, a process dependent on the functional 53BP1 tudor domain, thus confirming its cellular activity.</p>Formule :C14H21BrN2OC4H4O4Couleur et forme :SolidMasse moléculaire :429.31CDK9-IN-23
CAS :<p>CDK9-IN-23 (Example 4) is a potent inhibitor of CDK9, exhibiting an IC50 value of less than 20 nM [1].</p>Formule :C22H25ClN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.91Aurora kinase inhibitor-8
CAS :<p>Aurora kinase inhibitor-8 is a highly selective inhibitor of Aurora kinase.</p>Formule :C30H29N7O3Couleur et forme :SolidMasse moléculaire :535.6DUB-IN-7
CAS :<p>DUB-IN-7 (compound 43), a deubiquitinating enzyme (DUB) inhibitor, has utility in researching diseases driven by aberrant JAK2 activity, including leukemia [1].</p>Formule :C17H19N5OCouleur et forme :SolidMasse moléculaire :309.37m-Se3
CAS :<p>m-Se3 is a potent, selective inhibitor of c-MYC transcription with demonstrated capability to inhibit tumor growth and exhibit anti-cancer activity [1].</p>Formule :C29H23IN2SeDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :605.373-Hydroxyxanthone
CAS :<p>3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical vein</p>Formule :C13H8O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :212.2WRN inhibitor 2
CAS :<p>WRN Inhibitor 2 (example 118), a potent inhibitor of the WRN (Werner Syndrome ATP-dependent helicase enzyme), exhibits a pIC50 value of 7.0 or greater [1].</p>Formule :C15H11F3N2O5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.38Voruciclib hydrochloride
CAS :<p>Voruciclib hydrochloride is an orally active and selective inhibitor of CDK (Ki: 0.626 nM-9.1 nM).</p>Formule :C22H20Cl2F3NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.3ROCK-IN-9
CAS :<p>ROCK-IN-9 (Compound T345), a ROCK inhibitor, exhibits cytotoxicity in HepG2 cells with an IC50 of 40.8 μM.</p>Formule :C20H20FN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :381.4Gly-Arg-Gly-Asp-Ser TFA
CAS :<p>Gly-Arg-Gly-Asp-Ser (TFA), osteopontin domain, binds αvβ3 and αvβ5 integrins; IC50s: ~5 μM, ~6.5 μM.</p>Formule :C19H31F3N8O11Couleur et forme :SolidMasse moléculaire :604.49CDK4/6-IN-17
CAS :<p>CDK4/6-IN-17 (compound 12) is an orally bioavailable inhibitor of CDK4/6, demonstrating potent activity with IC50 values between 10-100 nM in BE(2) cells.</p>Formule :C27H28F4N8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :540.56CCG-232964
CAS :<p>CCG-232964 is an orally active Rho/MRTF/SRF inhibitor that suppresses LPA-induced CTGF gene expression [1].</p>Formule :C15H15ClN2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :338.81NU6300
CAS :<p>NU6300 is a covalent CDK2 inhibitor exhibiting irreversible and ATP-competitive properties and also functions as a GSDMD (Gasdermin D) inhibitor.</p>Formule :C20H23N5O3SDegré de pureté :96.08%Couleur et forme :SolidMasse moléculaire :413.49

