Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(114 produits)
- CDK(546 produits)
- Arrêt du cycle cellulaire(5 produits)
- Chk(48 produits)
- DYRK(47 produits)
- Dynamine(27 produits)
- Ferroptose(227 produits)
- HSP(179 produits)
- Intégrine(268 produits)
- Kinésine(87 produits)
- LIM Kinase(20 produits)
- Microtubules associés(274 produits)
- PKC(126 produits)
- PLK(25 produits)
- ROCK(62 produits)
- Rho(6 produits)
- Wee1(14 produits)
- c-Myc(76 produits)
Affichez 10 plus de sous-catégories
3897 produits trouvés pour "Cycle cellulaire/point de contrôle"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
3-deoxy-3-fluoro-β-D-Ribofuranose 25
CAS :Compound 25, β-D-Ribofuranose, 3-deoxy-3-fluoro-, 1,2-diacetate 5-(4-methylbenzoate), exhibits strong activity in inhibiting the growth of tumor cells [1].Formule :C17H19FO7Couleur et forme :SolidMasse moléculaire :354.33Glycyl H-1152 hydrochloride
CAS :Glycyl-H-1152 is a potent ROCK-II inhibitor (IC50=11.8 nM) with high selectivity over CaMKII, PKG, Aurora A, PKA, and PKC. Better than Y-27632 and HA-1077.Formule :C18H26Cl2N4O3SCouleur et forme :SolidMasse moléculaire :449.39FT3967385
FT3967385: New USP30 inhibitor boosts mitochondrial ubiquitylation via PINK1-PARKIN.Formule :C21H19N5O2Couleur et forme :SolidMasse moléculaire :373.41Dyrk1A/B-IN-1
Dyrk1A/B-IN-1 (3n) is a potent DYRK1A/B inhibitor, cell-permeable, with Ki values of 67.8 nM (1A) and 237.9 nM (1B), IC50s of 1.1 and 0.8 μM.Formule :C21H17N3O2S2Couleur et forme :SolidMasse moléculaire :407.51BRD-7880
CAS :BRD-7880 is a potent and highly specific inhibitor of aurora kinases B and C.Formule :C32H38N4O7Couleur et forme :SolidMasse moléculaire :590.67LNA-GDP
CAS :LNA-GDP is a nucleotide analog utilized in the synthesis of oligonucleotides.Formule :C11H15N5O11P2Couleur et forme :SolidMasse moléculaire :455.21Y-99
CAS :Y-99 is a PORCN inhibitor with an IC50 value of 155.4 nM for suppressing the Wnt/β-catenin signaling pathway. Additionally, Y-99 inhibits the expression of p-LRP6, β-catenin, and c-Myc.Formule :C18H17F2N5O3Couleur et forme :SolidMasse moléculaire :389.36Adafosbuvir
CAS :Adafosbuvir has antiviral activity.Formule :C22H29FN3O10PCouleur et forme :SolidMasse moléculaire :545.457AM-9022
CAS :AM-9022 is a potent and selective KIF18A inhibitor, orally active and suitable for cancer research [1].Formule :C27H36F2N6O4SCouleur et forme :SolidMasse moléculaire :578.67EX05
CAS :EX05, an effective KIF18A inhibitor, exhibits an IC50 of 8.2 nM and holds potential for cancer research applications.Formule :C26H30F2N4O5SCouleur et forme :SolidMasse moléculaire :548.60MtTMPK-IN-7
MtTMPK-IN-7 inhibits MtbTMPK (IC50: 47 μM), active against M. brevis (MIC: 2.3-4.7 μM), useful for tuberculosis research.Formule :C27H29ClN6O3Couleur et forme :SolidMasse moléculaire :521.01Zalunfiban dihydrochloride
Zalunfiban (RUC-4) is a potent αIIbβ3 platelet antagonist, IC50 45 nM, used in myocardial infarction research.Formule :C16H20Cl2N8O2SCouleur et forme :SolidMasse moléculaire :459.35α5β1 integrin agonist-1
CAS :α5β1 integrin agonist-1 is an α5β1 integrin agonist that selectively delivers 5-FU to tumour cells and induces tumour cell death.Formule :C24H26FN5O9Couleur et forme :SolidMasse moléculaire :547.49Antitumor agent-75
Antitumor agent-75 is a novel and potent antitumor agent.Formule :C26H23FN6Couleur et forme :SolidMasse moléculaire :438.55-Iminodaunorubicin hydrochloride
CAS :5-Iminodaunorubicin HCl: quinone-modified anthracycline with antitumor properties, induces DNA breaks in cancer cells.Formule :C27H31ClN2O9Couleur et forme :SolidMasse moléculaire :563.00CDK1-IN-7
CAS :CDK1-IN-7 (compound M7) is a potent CDK1 inhibitor. It effectively suppresses the proliferation and migration of HCT116 and Lovo cells, making it a valuable tool for colorectal cancer research.Formule :C23H19ClN4O3Couleur et forme :SolidMasse moléculaire :434.88Metesind Glucuronate
CAS :Metesind Glucuronate is an antineoplastic. It also is a specific thymidylate synthase inhibitor.Formule :C29H34N4O10SCouleur et forme :SolidMasse moléculaire :630.67And1 degrader 1
CAS :And1 degrader 1 (Compound A15) is a degrader of acidic nucleoplasmic DNA-binding protein 1 (And1) that notably induces degradation of And1 in NSCLC cells. When combined with Olaparib (1 μM), And1 degrader 1 at a concentration of 5 μM effectively inhibits proliferation in A549 and H460 cells. This compound is applicable in cancer research studies.Formule :C26H27Cl2N3OCouleur et forme :SolidMasse moléculaire :468.42VCPIP1-IN-1
CAS :VCPIP1-IN-1 is a VCPIP1 inhibitor used in cancer research.Formule :C13H15ClN2O2Degré de pureté :99.3%Couleur et forme :SolidMasse moléculaire :266.72Ref: TM-T88664
1mg47,00€5mg92,00€10mg145,00€25mg281,00€50mg447,00€100mg715,00€200mg964,00€1mL*10mM (DMSO)101,00€Elacytarabine
CAS :Elacytarabine (M7594 0037), a lipid-conjugated derivative of the nucleoside analog cytarabine, is an antineoplastic drug. It has cytotoxicity in solid tumors.Formule :C27H45N3O6Degré de pureté :97.69%Couleur et forme :SolidMasse moléculaire :507.66Zelasudil
CAS :Zelasudil (RXC007) is a Rho-related (ROCK) kinase inhibitor for the study of idiopathic pulmonary fibrosis and inflammation.Formule :C22H21F2N7ODegré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :437.445Ref: TM-T69665
1mg92,00€5mg168,00€10mg248,00€25mg421,00€50mg587,00€100mg820,00€1mL*10mM (DMSO)170,00€GFB-12811
CAS :GFB-12811 is an orally active, selective, and potent CDK5 inhibitor, used in the study of autosomal dominant polycystic kidney disease.Formule :C22H23F4N5ODegré de pureté :98.88%Couleur et forme :SolidMasse moléculaire :449.44USP15-IN-1
CAS :USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM).Formule :C22H23N3O3Degré de pureté :99.509% - 99.81%Couleur et forme :SolidMasse moléculaire :377.44CTPS1-IN-1
CAS :CTPS1-IN-1 is a cytidine-5′ triphosphate synthase 1 (CTPS1) inhibitor with potential antitumor activity and can be used to study autoimmune diseases.Formule :C21H22N6O4S2Degré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :486.57HRO761
CAS :HRO761 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomach cancer.Formule :C31H31ClF3N9O5Degré de pureté :98.74% - 99.62%Couleur et forme :SolidMasse moléculaire :702.08Ref: TM-T72107
1mg57,00€5mg118,00€10mg167,00€25mg280,00€50mg475,00€100mg708,00€1mL*10mM (DMSO)778,00€LY3143921 hydrate
CAS :LY3143921 ((S)-Example 2) hydrate is an orally active CDC7 kinase inhibitor with broad in vitro anticancer activity [1].Formule :C16H14FN5O2Degré de pureté :98.43%Couleur et forme :SolidMasse moléculaire :327.31SR 11302
CAS :SR 11302 is an inhibitor of activator protein-1 (AP-1).Formule :C26H32O2Degré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :376.53Ref: TM-T23384
1mg93,00€5mg137,00€10mg205,00€25mg356,00€50mg587,00€100mg888,00€1mL*10mM (DMSO)150,00€INCB086550
CAS :INCB086550 (PD-1/PD-L1-IN-8) (example 24) is a PD-1/PD-L1 inhibitor, with an IC50 <= 10 nM.Formule :C41H39N7O4Degré de pureté :98.49%Couleur et forme :SolidMasse moléculaire :693.79Bicyclomycin benzoate
CAS :Bicyclomycin benzoate (BCM benzoate, FR2054) is a broad-spectrum antibiotic and selective Rho protein inhibitor active against Gram-negative bacteria.Formule :C19H22N2O8Couleur et forme :SolidMasse moléculaire :406.39Troxacitabine
CAS :Troxacitabine, a DNA polymerase inhibitor, is potentially used for the treatment of acute myeloid leukemia (AML). In comparison with gemcitabine, troxacitabine was equally active against MiaPaCa and was more efficacious against Panc-01.Formule :C8H11N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :213.19Formycin A
CAS :Formycin A shows antitumor and antiviral activities. Formycin A , a purine nucleoside antibiotic, is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an EC50 of 10 μM.Formule :C10H13N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :267.24PLK1-IN-6
PLK1-IN-6: potent, selective PLK1 inhibitor, IC50 = 0.45 nM, hinders cancer cell growth.
Formule :C28H37N9O3Couleur et forme :SolidMasse moléculaire :547.653BrB-PP1
CAS :3BrB-PP1 is an ATP-competitive analog that exhibits specific inhibitory activity towards protein kinase, particularly effective against protein kinases with mutations in the ATP-binding pocket, such as the Thr97 mutation within Sty1's ATP-binding pocket.Formule :C16H18BrN5Couleur et forme :SolidMasse moléculaire :360.259Ethynylcytidine
CAS :Ethynylcytidine is a nucleoside antimetabolite.Formule :C11H13N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :267.24Tanuxiciclib
CAS :Tanuxiciclib is a cyclin dependent kinase (CDK) inhibitor, specifically designed to interfere with cell cycle progression by inhibiting the activity of CDKs, which are crucial regulators of cell division.Formule :C15H13FN6OCouleur et forme :SolidMasse moléculaire :312.3082'-Deoxy-2'-fluoro-5-iodouridine
CAS :2'-Deoxy-2'-fluoro-5-iodouridine is a nucleoside, specifically a fluoro-modified and halo-nucleoside.Formule :C9H10FIN2O5Couleur et forme :SolidMasse moléculaire :372.09GSK-3/CDK5/CDK2-IN-1
CAS :GSK-3/CDK5/CDK2-IN-1 is an imidazole derivative compound that inhibits cdk5, cdk2, and GSK-3.it has demonstrated applications in cancer research and the study of neurodegenerative diseases [1].Formule :C21H22N4O2Couleur et forme :SolidMasse moléculaire :362.433NSC639828
CAS :NSC639828 is an efficient inhibitor of DNA polymerase α, exhibiting a remarkable IC50 value of 70 μM. Additionally, NSC639828 demonstrates substantial antitumor activity, making it a promising candidate for cancer research.Formule :C18H13BrClN5O3Couleur et forme :SolidMasse moléculaire :462.695'-DMT-3'-TBDMS-ibu-rG
CAS :5'-DMT-3'-TBDMS-ibu-rG is a modified nucleoside employed in deoxyribonucleic acid (DNA) synthesis.Formule :C41H51N5O8SiCouleur et forme :SolidMasse moléculaire :769.965'-O-DMT-N6-ibu-dA
CAS :5'-O-DMT-N6-ibu-dA can be utilized in the synthesis of oligodeoxyribonucleotides.Formule :C35H37N5O6Couleur et forme :SolidMasse moléculaire :623.71N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine
CAS :N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine, catalog number T66118 and CAS number 64325-78-6, is a valuable organic compound for life sciences research.Formule :C38H35N5O6Couleur et forme :SolidMasse moléculaire :657.727MitoE10
CAS :MitoE10 is an effective mitochondrial targeting antioxidant.Formule :C42H55O5PSCouleur et forme :SolidMasse moléculaire :702.926-Amino-5-nitropyridin-2-one
CAS :6-Amino-5-nitropyridin-2-one, a pyridine derivative, serves as a nucleobase within hachimoji DNA, where it is specifically paired with 5-aza-7-deazaguanine.Formule :C5H5N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :155.11Ribocil-C
CAS :Ribocil-C is a selective inhibitor of the bacterial riboflavin riboswitch, a synthetic analogue of flavin mononucleotide (FMN), inhibits bacterial cell growth.Formule :C21H21N7OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.5Tibremciclib
CAS :Tibremciclib is a cyclin-dependent kinase 4 (CDK4) inhibitor that exhibits antineoplastic properties [1].
Formule :C28H32F2N8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :518.6PHI-101
CAS :PHI-101 is a checkpoint kinase 2 (Chk2) inhibitor that can be used for the study of refractory acute myeloid leukemia (AML) and ovarian cancer.
Formule :C19H19FN4O2SDegré de pureté :99.4%Couleur et forme :SolidMasse moléculaire :386.44YK-2168
CAS :YK-2168 is a differentiated selective inhibitor of CDK9.
Formule :C16H18ClN5Couleur et forme :SolidMasse moléculaire :315.80
