
Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(114 produits)
- CDK(546 produits)
- Arrêt du cycle cellulaire(5 produits)
- Chk(48 produits)
- DYRK(47 produits)
- Dynamine(27 produits)
- Ferroptose(227 produits)
- HSP(180 produits)
- Intégrine(269 produits)
- Kinésine(87 produits)
- LIM Kinase(20 produits)
- Microtubules associés(274 produits)
- PKC(126 produits)
- PLK(25 produits)
- ROCK(62 produits)
- Rho(6 produits)
- Wee1(14 produits)
- c-Myc(76 produits)
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3904 produits trouvés pour "Cycle cellulaire/point de contrôle"
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AS2863619
CAS :AS2863619 is an oral inhibitor of cyclin-dependent kinase(CDK8) and CDK19. Inhibition of CDK8/19 enhances STAT5 activation.Cost-effective and quality-assured.Formule :C16H14Cl2N8ODegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :405.24Ref: TM-T8378
1mg124,00€2mg170,00€5mg260,00€10mg409,00€25mg677,00€50mg954,00€100mg1.288,00€1mL*10mM (DMSO)286,00€BRD9876
CAS :BRD9876 is a selective inhibitor of MM1S growth.Formule :C16H14N2Degré de pureté :97.81%Couleur et forme :SolidMasse moléculaire :234.3RK33
CAS :"RK33 is a DDX3 inhibitor causing G1 arrest, apoptosis, and radiation sensitization in DDX3-overexpressing cells."Formule :C23H20N6O3Degré de pureté :99.04% - 99.72%Couleur et forme :SolidMasse moléculaire :428.44T-5224
CAS :T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcriptionFormule :C29H27NO8Degré de pureté :97.88% - 99.29%Couleur et forme :SolidMasse moléculaire :517.53Ref: TM-T5416
1mg48,00€5mg96,00€10mg144,00€25mg254,00€50mg424,00€100mg627,00€200mg998,00€1mL*10mM (DMSO)107,00€Pyridostatin TFA
CAS :Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-Formule :C37H35F9N8O11Degré de pureté :97.09% - 99.84%Couleur et forme :SolidMasse moléculaire :938.71BUR1
CAS :BUR1 is a Saccharomyces cerevisiae cyclin-dependent kinase (CDK) and is homologous to mammalian Cdk9, which functions in transcriptional elongation.Formule :C16H17N5Degré de pureté :90%Couleur et forme :SolidMasse moléculaire :279.34LP-935509
CAS :LP-935509 is a selective, brain-permeable, small molecule competitive inhibitor of articulin-2-associated kinase 1 (AAK1).Cost-effective and quality-assured.Formule :C20H24N6O3Degré de pureté :98.34% - 99.64%Couleur et forme :SolidMasse moléculaire :396.44Ref: TM-T15781
1mg37,00€2mg49,00€5mg79,00€10mg124,00€25mg239,00€50mg444,00€100mg647,00€1mL*10mM (DMSO)87,00€H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS :RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.Formule :C23H38N10O10Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :614.61Alovudine
CAS :3'-Fluoro-3'-deoxythymidine (3'-Deoxy-3'-fluorothymidine) is a marker of DNA synthesis,which is less susceptible to inflammatory changes than FDG.Formule :C10H13FN2O4Degré de pureté :99.41%Couleur et forme :Less Solid Colourless SolidMasse moléculaire :244.22Dasabuvir
CAS :Dasabuvir (ABT-333) blocks HCV replication by inhibiting the essential NS5B RNA polymerase.Formule :C26H27N3O5SDegré de pureté :99.54% - 99.62%Couleur et forme :SolidMasse moléculaire :493.57Peldesine dihydrochloride
CAS :Peldesine (BCX 34) dihydrochloride is an inhibitor of PNP in humans, rats, and mice, also hindering T-cell proliferation, used in lymphoma and HIV research.Formule :C12H13Cl2N5OCouleur et forme :SolidMasse moléculaire :314.176-Chloropurine riboside
CAS :6-Chloropurine riboside (6-CPR): purine analog with antitumor, anti-inflammatory, antiviral, antifungal effects, and neuroprotective properties.Formule :C10H11ClN4O4Degré de pureté :96.84%Couleur et forme :SoildMasse moléculaire :286.6700CKI-7 free base
CAS :CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.Formule :C11H12ClN3O2SCouleur et forme :SolidMasse moléculaire :285.75Orbofiban
CAS :Orbofiban, an orally administered antagonist of the platelet GPIIb/IIIa receptor, effectively inhibits platelet aggregation.Formule :C17H23N5O4Couleur et forme :SolidMasse moléculaire :361.4Apcin
CAS :Apcin: potent APC/C(Cdc20) E3 ligase inhibitor, blocks substrate recognition & mitosis, synergizes with Ts-Arg-OMe.Formule :C13H14Cl3N7O4Degré de pureté :96.74%Couleur et forme :SolidMasse moléculaire :438.65Ref: TM-T8561
1mg46,00€2mg59,00€5mg93,00€10mg133,00€25mg259,00€50mg447,00€100mg673,00€1mL*10mM (DMSO)92,00€CHR-6494
CAS :CHR-6494 is a haspin inhibitor that inhibits histone H3T3 phosphorylation (IC50: 2 nM).Formule :C16H16N6Degré de pureté :98.78%Couleur et forme :SolidMasse moléculaire :292.34Ref: TM-T14959
5mg54,00€10mg82,00€25mg145,00€50mg259,00€100mg442,00€200mg643,00€1mL*10mM (DMSO)60,00€Brr2-IN-3
CAS :Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa.Formule :C24H20N4O3SDegré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :444.51Ref: TM-T22282
1mg52,00€2mg65,00€5mg92,00€10mg161,00€25mg290,00€50mg420,00€100mg587,00€200mg792,00€1mL*10mM (DMSO)110,00€Brequinar
CAS :Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.Formule :C23H15F2NO2Degré de pureté :99.1% - 99.57%Couleur et forme :SolidMasse moléculaire :375.37Bonafton
CAS :Bonafton (Bonaphthone) is an antiviral agent.Formule :C10H5BrO2Degré de pureté :97.16%Couleur et forme :SolidMasse moléculaire :237.05Ref: TM-T8877
1mg56,00€5mg118,00€10mg167,00€25mg281,00€50mg421,00€100mg605,00€200mg845,00€1mL*10mM (DMSO)92,00€3-Deazauridine
CAS :3-Deazauridine (NSC-126849), a uridine analog, blocks CTP synthesis by competing with CTP synthetase.Formule :C10H13NO6Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :243.21kb-NB77-78
CAS :kb-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673(PKD1 inhibitor).Formule :C18H25NO3SiDegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :331.48EHT 1864 2HCl
CAS :EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3. Cost effective and quality assured.Formule :C25H29Cl2F3N2O4SDegré de pureté :98.39% - 99.42%Couleur et forme :SolidMasse moléculaire :581.47Fanotaprim
CAS :Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor.Formule :C19H22N8ODegré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :378.43Ref: TM-T36692
1mg50,00€2mg71,00€5mg110,00€10mg170,00€25mg318,00€50mg442,00€100mg627,00€200mg845,00€1mL*10mM (DMSO)122,00€HA-100
CAS :HA-100 is an inhibitor of protein kinaseFormule :C13H15N3O2SDegré de pureté :99.44%Couleur et forme :Pale Yellow Crystalline SolidMasse moléculaire :277.34PNU112455A hydrochloride
CAS :PNU112455A hydrochloride is an ATP site competetive inhibitor of CDK2 and CDK5,binds to the ATP site of CDK2 and CDK5 with Kms of 3.6 and 3.2 μM, respectively.Formule :C10H12ClN5O2SDegré de pureté :98.58% - 99.22%Couleur et forme :SolidMasse moléculaire :301.75Ref: TM-T8230
2mg44,00€5mg71,00€10mg100,00€25mg172,00€50mg266,00€100mg434,00€500mg964,00€1mL*10mM (DMSO)79,00€Ribociclib succinate hydrate
CAS :Ribociclib succinate hydrate is a highly specific CDK4/6 inhibitor (IC50s: 10 nM and 39 nM, respectively).Formule :C27H38N8O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :570.651CAN508
CAS :CAN508: potent CDK9/T1 inhibitor; IC50 0.35 μM, Cdk2/E; Ki 13.3 μM, IC50 20 μM; 38x selective; antitumor.Formule :C9H10N6ODegré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :218.22TAK-632
CAS :TAK-632 is a potent pan-Raf inhibitor.Formule :C27H18F4N4O3SDegré de pureté :98% - 99.5%Couleur et forme :SolidMasse moléculaire :554.52Palmatine
CAS :Palmatine, also known as Burasaine, inhibits dopamine production and may treat flavivirus, jaundice, dysentery, hypertension, and liver issues.Formule :C21H22NO4Degré de pureté :96.28% - 99.49%Couleur et forme :SolidMasse moléculaire :352.4SPHINX
CAS :SPHINX is a new generation inhibitor of SPRK1Formule :C17H17F3N2O3Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :354.32Hu7691
CAS :Hu7691 is an Akt inhibitor that inhibits Akt1, Akt2, and Akt3, suppresses neuroblastoma cell proliferation, and induces differentiation of neuroblastoma cells.Formule :C22H22ClF3N4ODegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :450.887BIO
CAS :7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.
Formule :C16H10BrN3O2Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :356.17SBC-115337
CAS :SBC-115337 is a PCSK9 inhibitor.Formule :C29H19N3O4Degré de pureté :99.41%Couleur et forme :SolidMasse moléculaire :473.48Simeprevir
CAS :Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.Formule :C38H47N5O7S2Degré de pureté :99.45% - 99.92%Couleur et forme :SolidMasse moléculaire :749.94WR99210 hydrochloride(47326-86-3 free base)
CAS :WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target.Formule :C14H19Cl4N5O2Degré de pureté :97.77% - 99.8%Couleur et forme :SolidMasse moléculaire :431.14Ref: TM-T17257L
1mg62,00€5mg132,00€10mg200,00€25mg338,00€50mg497,00€100mg708,00€200mg954,00€1mL*10mM (DMSO)157,00€WNK-IN-11
CAS :WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)Formule :C21H21Cl2N5OSDegré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :462.4Ref: TM-T5456
1mg87,00€5mg172,00€10mg280,00€25mg474,00€50mg683,00€100mg964,00€500mg1.918,00€1mL*10mM (DMSO)188,00€3'-Deoxyguanosine
CAS :3'-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors.Formule :C10H13N5O4Degré de pureté :98.85% - 98.96%Couleur et forme :SolidMasse moléculaire :267.24Phosphonoformic acid trisodium salt hexa
CAS :Phosphonoformic acid trisodium salt hexa (Sodium phosphonatoformate hexahydrate) is an antiviral drug for the treatment of CMV retinitis.Formule :CH12Na3O11PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :300.03Cyclo(RGDyK) trifluoroacetate
CAS :Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.Formule :C31H43F6N9O12Degré de pureté :95.28% - ≥95%Couleur et forme :SolidMasse moléculaire :847.72PfDHODH-IN-1
CAS :PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.Formule :C14H11F3N2O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :296.24Ref: TM-T12438
1mg52,00€5mg101,00€10mg152,00€25mg295,00€50mg447,00€100mg658,00€200mg888,00€1mL*10mM (DMSO)92,00€GAK inhibitor 49 hydrochloride
Potent GAK inhibitor 49 hydrochloride: ATP-competitive, highly selective, Ki=0.54 nM, IC50=56 nM, binds to RIPK2.Formule :C20H23ClN2O5Couleur et forme :SolidMasse moléculaire :406.86Tirapazamine
CAS :Tirapazamine (Win59075) triggers apoptosis in hypoxic cells by damaging DNA and enhances effects of radiation and cisplatin.Formule :C7H6N4O2Degré de pureté :96.65% - 99.87%Couleur et forme :Orange-Red Crystalline PowderMasse moléculaire :178.15LDN-192960 hydrochloride
CAS :LDN-192960 hydrochloride is an inhibitor of Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) and Haspin with IC50s of 48 nM and 10 nM, respectively.Formule :C18H22Cl2N2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :401.35Levofloxacin hydrochloride
CAS :Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.Formule :C18H21ClFN3O4Degré de pureté :99.78% - 99.98%Couleur et forme :SolidMasse moléculaire :397.8Lurbinectedin
CAS :Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.Formule :C41H44N4O10SDegré de pureté :98.11%Couleur et forme :SolidMasse moléculaire :784.87M2N12
CAS :M2N12 selectively inhibits Cdc25C (IC50=0.09μM) and has anti-tumor properties, affecting Cdc25A and B as well.Formule :C20H16ClN5O2Degré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :393.83Ref: TM-T11929
1mg84,00€5mg152,00€10mg236,00€25mg447,00€50mg670,00€100mg982,00€1mL*10mM (DMSO)167,00€CRT0066854
CAS :CRT-0066854 is a PKCι and PKCζ inhibitor. CRT0066854 was able to restore polarized morphogenesis in the dysplastic H-Ras spheroids.Formule :C24H25N5SCouleur et forme :SolidMasse moléculaire :415.55Mps1-IN-3 hydrochloride
Mps1-IN-3 HCl: potent Mps1 inhibitor (IC50: 50 nM), hampers glioblastoma growth, enhances vincristine efficacy in vivo.Formule :C26H32ClN7O4SCouleur et forme :SolidMasse moléculaire :574.09Tipiracil
CAS :Tipiracil inhibits thymidine phosphorylase, enhancing trifluridine bioavailability, and is studied in colorectal and gastric cancer treatment.Formule :C9H11ClN4O2Degré de pureté :99.815%Couleur et forme :SolidMasse moléculaire :242.66Vidofludimus
CAS :Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).Formule :C20H18FNO4Degré de pureté :98.33% - 99.58%Couleur et forme :SolidMasse moléculaire :355.36

