Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(95 produits)
- CDK(501 produits)
- Arrêt du cycle cellulaire(4 produits)
- Chk(42 produits)
- DYRK(48 produits)
- Dynamine(23 produits)
- Ferroptose(215 produits)
- HSP(169 produits)
- Intégrine(224 produits)
- Kinésine(66 produits)
- LIM Kinase(19 produits)
- Microtubules associés(262 produits)
- PKC(102 produits)
- PLK(28 produits)
- ROCK(69 produits)
- Rho(2 produits)
- Wee1(15 produits)
- c-Myc(69 produits)
Affichez 10 plus de sous-catégories
3485 produits trouvés pour "Cycle cellulaire/point de contrôle"
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PfDHODH-IN-1
CAS :<p>PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.</p>Formule :C14H11F3N2O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :296.24Cyclo(RGDyK) trifluoroacetate
CAS :<p>Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.</p>Formule :C31H43F6N9O12Degré de pureté :95.28% - ≥95%Couleur et forme :SolidMasse moléculaire :847.72BAY-1816032
CAS :<p>BAY-1816032 is a benzimidazole budding inhibition relieved homolog protein 1 kinase (BUB1) inhibitor.Cost-effective and quality-assured.</p>Formule :C27H24F2N6O4Degré de pureté :98.02% - 99.81%Couleur et forme :SolidMasse moléculaire :534.51Isoindigotin
CAS :<p>Isoindigotin is used in the therapy of Y.</p>Formule :C16H10N2O2Degré de pureté :98.14% - ≥95%Couleur et forme :SolidMasse moléculaire :262.26SRI-29329
CAS :<p>SRI-29329 is a potent, specific inhibitor of CDC-like kinase (with IC50 of 78 nM, 16 nM and 86 nM for CLK1, CLK2 and CLK4, respectively).</p>Formule :C20H26ClN7Degré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :399.92NSC23005
CAS :<p>NSC23005 sodium is a p18INK inhibitor with potently promoted hematopoietic stem cell (HSC) expansion (ED50: 5.21 nM).</p>Formule :C13H17NO4SDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :283.34Dasabuvir
CAS :<p>Dasabuvir (ABT-333) blocks HCV replication by inhibiting the essential NS5B RNA polymerase.</p>Formule :C26H27N3O5SDegré de pureté :99.54% - 99.62%Couleur et forme :SolidMasse moléculaire :493.57Lifitegrast
CAS :<p>Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.</p>Formule :C29H24Cl2N2O7SDegré de pureté :99.39% - 99.66%Couleur et forme :SolidMasse moléculaire :615.48TH287 hydrochloride
CAS :<p>TH287 inhibits MTH1 (IC50: 0.8 nM), causing DNA damage in cancer cells through oxidized dNTP incorporation, leading to cytotoxicity in mouse xenografts.</p>Formule :C11H11Cl3N4Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :305.59ILK-IN-3
CAS :ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.Formule :C10H12N6ODegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :232.24CDK9-IN-30
CAS :<p>CDK9-IN-30 is one of the Tat peptide derivatives and inhibits HIV-1 long terminal repeat-activated transcription.</p>Formule :C16H20FNO3Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :293.33Talotrexin
CAS :<p>Talotrexin (PT523), a nonpolyglutamatable antifolate analog of Aminopterin, inhibits DHFR and RFC, targeting tumor growth.</p>Formule :C27H27N9O6Couleur et forme :SolidMasse moléculaire :573.56Temozolomide Acid
CAS :<p>TMZA, a TMZ metabolite, shows in vitro anticancer effects. TMZ, an oral alkylator, treats GBM and astrocytomas.</p>Formule :C6H5N5O3Degré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :195.14ZM-447439
CAS :<p>ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.</p>Formule :C29H31N5O4Degré de pureté :99.11% - 99.59%Couleur et forme :Pale Yellow SolidMasse moléculaire :513.59Peldesine dihydrochloride
CAS :<p>Peldesine (BCX 34) dihydrochloride is an inhibitor of PNP in humans, rats, and mice, also hindering T-cell proliferation, used in lymphoma and HIV research.</p>Formule :C12H13Cl2N5OCouleur et forme :SolidMasse moléculaire :314.17Chroman 1 dihydrochloride
<p>Chroman 1 dihydrochloride: potent ROCK2 inhibitor (IC50: 1 pM), also affects ROCK1 (52 pM) and MRCK (150 nM).</p>Formule :C24H30Cl2N4O4Couleur et forme :SolidMasse moléculaire :509.43Cyclo(RADfK)
CAS :<p>Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.</p>Formule :C28H43N9O7Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :617.76-Chloropurine riboside
CAS :<p>6-Chloropurine riboside (6-CPR): purine analog with antitumor, anti-inflammatory, antiviral, antifungal effects, and neuroprotective properties.</p>Formule :C10H11ClN4O4Degré de pureté :96.84%Couleur et forme :SoildMasse moléculaire :286.6700SR18662
<p>SR18662, improved ML264 derivative, inhibits KLF5 at 4.4 nM IC50; curbs colorectal cancer cell growth and triggers apoptosis.</p>Formule :C16H19Cl2N3O4SDegré de pureté :98.97% - 99.2%Couleur et forme :SolidMasse moléculaire :420.31Trilaciclib
CAS :<p>Trilaciclib is a short-acting, orally effective CDK4/6 inhibitor with IC₅₀ values of 1 nM and 4 nM respectively. enhances antitumour immunity.</p>Formule :C24H30N8ODegré de pureté :99.624%Couleur et forme :SolidMasse moléculaire :446.55Pyridostatin Trihydrochloride
CAS :<p>Pyridostatin Trihydrochloride (RR-82 Trihydrochloride) is a G-quadruplexe stabilizer, with a Kd of 490 nM.</p>Formule :C31H35Cl3N8O5Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :706.02EG1
CAS :<p>EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.</p>Formule :C22H18N2O5Degré de pureté :97.48%Couleur et forme :SolidMasse moléculaire :390.392'-Deoxy-N4-methylcytidine
CAS :<p>2’-Deoxy-N4-methylcytidine (N(3)-Methyl-2'-deoxycytidine) is a purine nucleoside analog with potential antitumor activity for the study of apoptosis.</p>Formule :C10H15N3O4Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :241.24ARB-272572
CAS :<p>ARB-272572 is a PD-L1 signaling inhibitor that produces immunostimulatory activity in human primary cells.</p>Formule :C32H36N6O4Degré de pureté :97.36% - 98.07%Couleur et forme :SolidMasse moléculaire :568.67O6-Methyldeoxy guanosine
CAS :<p>O6-Methyldeoxy guanosine, a deoxypurine nucleoside, is a weak inhibitor of the removal of O6-methylguanine from methylated DNA by rat liver enzymes in vitro.</p>Formule :C11H15N5O4Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :281.272'-Deoxy-N2-methylguanosine
CAS :<p>2'-Deoxy-N2-methylguanosine is a purine nucleoside analog that can be used as a chemical probe to study DNA-protein interactions.</p>Formule :C11H15N5O4Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :281.27CDK12-IN-5
CAS :<p>CDK12-IN-5 is a potent CDK12 inhibitor with potential anticancer and antitumor activity, and can be used orally in the study of breast and ovarian cancer.</p>Formule :C18H15F5N8ODegré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :454.362'-O-Methyl-2-thiouridine
CAS :<p>2'-O-Methyl-2-thiouridine, a purine nucleoside analog present in synthetic thermophilic bacterial tRNAs, is more selective for A than unmodified U.</p>Formule :C10H14N2O5SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :274.29DS44960156
CAS :<p>DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.</p>Formule :C20H15NO5Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :349.342'-C-β-Methylguanosine
CAS :<p>2'-C-beta-Methylguanosine (2'-C-Methylguanosine), with antiviral activity, inhibits dengue virus 2.</p>Formule :C11H15N5O5Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :297.275'-O-DMT-N4-Bz-5-Me-dC
CAS :<p>5'-O-DMT-N4-Bz-5-Me-dC (DMT-NBZ-5-METHYL DC) is a modified nucleoside used in the synthesis of nucleoside phosphoramidites.</p>Formule :C38H37N3O7Degré de pureté :98.88%Couleur et forme :SolidMasse moléculaire :647.72P-2'-deoxyribose
CAS :<p>P-2'-deoxyribose (P-Nucleoside) is a deoxyribose that is widely found in organisms.</p>Formule :C11H15N3O5Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :269.252'-O-(2-Methoxyethyl)adenosine
CAS :<p>2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.</p>Formule :C13H19N5O5Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :325.32Braco-19
CAS :<p>Braco-19 is a telomerase/telomere inhibitor and an inhibitor of HAdV viral replication with antiviral activity that reduces lipid vacuolization in adipocytes, inhibits proliferation and decreases telomerase activity in human glioblastoma cells.</p>Formule :C35H43N7O2Degré de pureté :97.01%Couleur et forme :SolidMasse moléculaire :593.765-Bromouridine
CAS :<p>5-Bromouridine is a antitumor uracil derivative that induces apoptosis in cancer cells by inhibiting DNA synthesis and is also a marker for DNA and RNA.</p>Formule :C9H11BrN2O6Degré de pureté :99.89%Couleur et forme :White PowderMasse moléculaire :323.1N6-(2-Hydroxyethyl)adenosine
CAS :<p>N6-(2-Hydroxyethyl)adenosine is a sedative, Ca2+ antagonist, and anti-inflammatory, affecting brain and heart blood flow.</p>Formule :C12H17N5O5Degré de pureté :99.4%Couleur et forme :SolidMasse moléculaire :311.295-Bromo-2',3',5'-tri-O-acetyluridine
CAS :<p>5-Bromo-2',3',5'-tri-O-acetyluridine is a purine nucleoside analog that can be used to explore explore improve Parkinson's disease.</p>Formule :C15H17BrN2O9Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :449.21RO0270608
CAS :<p>RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.</p>Formule :C24H19Cl3N2O4Degré de pureté :98.26%Couleur et forme :SolidMasse moléculaire :505.782',3'-Bis-(O-t-butyldimethylsilyl)uridine
CAS :<p>2',3'-Bis-(O-t-butyldimethylsilyl)uridine is a nucleoside derivative protect the NH2/OH groups of nucleosides.inhibitory on viral replication，AIDS and herpes.</p>Formule :C21H40N2O6Si2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :472.72Bexotegrast
CAS :<p>Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).</p>Formule :C27H36N6O3Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :492.613'-Deoxy-3'-fluoroadenosine
CAS :<p>3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue with a wide range of anti-tumor and anti-viral activity, and has inhibitory effects on tick-borne</p>Formule :C10H12FN5O3Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :269.23N6-Methyl-2'-O-methyladenosine
CAS :<p>N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound found</p>Formule :C12H17N5O4Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :295.299-(β-D-Xylofuranosyl)adenine
CAS :<p>9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine has</p>Formule :C10H13N5O4Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :267.24Muromonab
CAS :<p>Muromonab (OKT3) is a mouse-derived antibody targeting the CD3 receptor, blocking all cytotoxic T cell functions.</p>Degré de pureté :95% - 97.51% (SEC-HPLC)Couleur et forme :Liquid5-Hydroxyuridine
CAS :<p>5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue with potential antitumour activity, showing cytotoxicity against human colon adenocarcinoma cell lines.</p>Formule :C9H12N2O7Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :260.2PolQi2
CAS :<p>PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.</p>Formule :C21H16ClN5O3SDegré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :453.9N6-(p-Methoxybenzyl)adenosine
CAS :<p>Nucleoside Derivatives - 6-Modified purine nucleosides; Drugs and Inhibitors; plant growth regulator, plant hormone</p>Formule :C18H21N5O5Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :387.39Z62954982
CAS :<p>Z62954982 (ZINC08010136) is a Rac1 inhibitor that inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arteries</p>Formule :C20H21N3O5SDegré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :415.46BC-1471
CAS :<p>BC-1471 is a STAMBP deubiquitinase inhibitor that blocks NALP7 inflammasome activity.</p>Formule :C27H32N4O4SDegré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :508.63AZ5576
CAS :<p>AZ5576 is a potent and highly selective CDK9 inhibitor. AZ5576 can be used for the research of Hematological Malignancy [1].</p>Formule :C21H24FN3O3Degré de pureté :99.88%Couleur et forme :SoildMasse moléculaire :385.43
