Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(95 produits)
- CDK(501 produits)
- Arrêt du cycle cellulaire(4 produits)
- Chk(42 produits)
- DYRK(48 produits)
- Dynamine(23 produits)
- Ferroptose(215 produits)
- HSP(169 produits)
- Intégrine(224 produits)
- Kinésine(66 produits)
- LIM Kinase(19 produits)
- Microtubules associés(262 produits)
- PKC(102 produits)
- PLK(28 produits)
- ROCK(69 produits)
- Rho(2 produits)
- Wee1(15 produits)
- c-Myc(69 produits)
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3485 produits trouvés pour "Cycle cellulaire/point de contrôle"
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Rabacfosadine
CAS :<p>Rabacfosadine (GS-9219) is a novel prodrug of PMEG, an acyclic nucleotide phosphonate, with antitumor activity for the study of lymphoma.</p>Formule :C21H35N8O6PDegré de pureté :99.06% - 99.37%Couleur et forme :SolidMasse moléculaire :526.53PDD00017273
CAS :<p>PDD00017273 is a radiosensitizing PARG) inhibitor with antitumor or activity for the study of epithelial ovaries.</p>Formule :C23H26N6O4S2Degré de pureté :99.14% - 99.21%Couleur et forme :SolidMasse moléculaire :514.622'-Deoxy-2-iodoadenosine
CAS :2'-Deoxy-2-iodoadenosine is a purine nucleoside analog with potential antimicrobial, antioxidant and anti-leukemic activities.Formule :C10H12IN5O3Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :377.14Etaracizumab
CAS :<p>Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.</p>Degré de pureté :96.77% (SEC-HPLC) - 99.32% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :144.3 (kDa)LSN2839567
CAS :<p>LSN2839567 (Abemaciclib metabolite M2) is a CDK4 and CDK6 inhibitor with anticancer activity, inhibits CDK9, and can be used in breast cancer research.</p>Formule :C25H28F2N8Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :478.54MK-5108
CAS :<p>MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.</p>Formule :C22H21ClFN3O3SDegré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :461.94Mps1-IN-2
CAS :<p>Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.</p>Formule :C26H36N6O3Degré de pureté :96.24% - 99.75%Couleur et forme :SolidMasse moléculaire :480.6SCH-1473759 hydrochloride
CAS :<p>SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).</p>Formule :C20H27ClN8OSDegré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :463DHX9-IN-8
CAS :<p>DHX9-IN-8 (Compound 6) functions as an inhibitor of the RNA helicase DHX9, exhibiting an EC50 of 3.4 μM for cellular target engagement within DHX9. It is primarily utilized in cancer research [1].</p>Formule :C18H16N2O3S2Couleur et forme :SolidMasse moléculaire :372.46Gresonitamab
CAS :<p>Gresonitamab (AMG 910) is an HLE BiTE antibody targeting CD3+ T cells and CLDN18.2+ tumors, for adenocarcinoma research.</p>Couleur et forme :LiquidCevostamab
CAS :<p>Cevostamab (BFCR4350A, RG6160, RO7187797) is a humanized BsAb IgG1 targeting FcRH5 on MM cells and CD3 on T cells to enhance T-cell-mediated MM cell killing.</p>Couleur et forme :LiquidRovelizumab
CAS :<p>Rovelizumab: humanized anti-CD11/CD18 antibody for MS, hemorrhagic shock, MI, and stroke research.</p>Couleur et forme :LiquidVibecotamab
CAS :<p>Vibecotamab, a bispecific antibody, targets CD123/CD3 for T-cell killing of tumors, promising for acute myeloid leukemia.</p>Couleur et forme :LiquidEnlimomab
CAS :<p>Enlimomab (BI-RR 0001), a mouse IgG2a antibody, blocks leukocyte binding to ICAM-1, reducing inflammation and used in stroke research.</p>Couleur et forme :LiquidVonsetamig
CAS :<p>Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.</p>Couleur et forme :LiquidAnti-Mouse CD3ε Antibody (145-2C11)
<p>Anti-Mouse CD3ε Antibody (145-2C11) is an antibody inhibitor targeting CD3ε in Armenian hamsters, in TCR formation and in T lymphocyte activation</p>Degré de pureté :99%Couleur et forme :Odour LiquidPOSH-IN-1
CAS :<p>POSH-IN-1 (Compound 108) is an inhibitor of the POSH polypeptide （e3 ligase) and has antiviral, anticancer, and neurodegenerative disease potential.</p>Formule :C14H8FNO3SDegré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :289.28Pacanalotamab
CAS :<p>Pacanalotamab (AMG 420/BI-836909), a BiTE, directs T-cells to BCMA+ MM cells, causing lysis.</p>Couleur et forme :Liquid5-Methyl-5,6-dihydrouridine
CAS :<p>5-Methyl-5,6-dihydrouridine is a minor constituent in the chromosomal RNA of the rat ascites tumor. It can be used for nucleic acid modification.</p>Formule :C10H16N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :260.24Locked nucleic acid 1
CAS :<p>Locked nucleic acid 1 is an LNA-type nucleoside derivative.</p>Formule :C32H32N2O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :572.61Obrindatamab
CAS :<p>Obrindatamab: a humanized bispecific antibody targeting B7-H3/CD3, enhances CTL-mediated cancer cell killing.</p>Couleur et forme :LiquidOS-2966
<p>OS-2966 is a humanised de-immunised monoclonal antibody that target Integrin b1/ITGB1/CD29, malignant gliomas, glioblastomas, and astrocytomas.</p>Degré de pureté :95%Couleur et forme :Odour LiquidVatelizumab
CAS :<p>Vatelizumab is a humanised monoclonal antibody targeting Integrin α2β1 ( VLA-2, CD49b), which enhances the frequency of regulatory T cells multiple sclerosis.</p>Degré de pureté :95%Couleur et forme :LiquidPasotuxizumab
CAS :<p>Pasotuxizumab (BAY 2010112) is a BiTE that targets PSMA & CD3 with K D s 47.0 & 9.4 nM, for mCRPC research.</p>Couleur et forme :LiquidAnti-Mouse IL-1a Antibody (ALF-161)
<p>Anti-Mouse IL-1a Antibody is an IgG1 subtype inhibitor specific to mouse IL-1a, derived from the Armenian Hamster.</p>Degré de pureté :98%Couleur et forme :Odour LiquidVoxalatamab
CAS :<p>Voxalatamab (JNJ-63898081), an IgG4 bispecific antibody targeting PSMA and CD3, demonstrates anti-cancer efficacy in prostate cancer research [1].</p>Couleur et forme :LiquidVepsitamab
CAS :<p>Vepsitamab (AMG 199), an anti-MUC17/CD3 BiTE, targets T cells and tumors for cell lysis and T cell activation.</p>Couleur et forme :LiquidRinatabart
CAS :<p>Rinatabart is a humanised monoclonal antibody targeting FRα/FOLR1, suitable for investigating ovarian and endometrial cancers expressing FRα.</p>Degré de pureté :95% - 95%Couleur et forme :Odour LiquidN6-Etheno 2'-deoxyadenosine
CAS :<p>N6-Etheno 2'-deoxyadenosine is used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues.</p>Formule :C12H13N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :275.26Ubamatamab
CAS :<p>Ubamatamab (REGN4018), a human bispecific antibody targeting Mucin 16 (MUC16) and CD3, exhibits potent antitumor activity [1].</p>Couleur et forme :LiquidMetribuzin
CAS :<p>Metribuzin is a selective herbicide used on crops like soybeans and potatoes. It inhibits photosynthesis and is a persistent groundwater contaminant.</p>Formule :C8H14N4OSDegré de pureté :99.07%Couleur et forme :Colorless Crytals Metribuzin Is A Colorless Crystalline Solid Used As An Herbicide (Niosh 2016)Masse moléculaire :214.29Pavurutamab
CAS :<p>Pavurutamab (AMG-701) is a bispecific T cell engager targeting CD3 and BCMA with extended half-life, designed to treat MM.</p>Couleur et forme :LiquidGSK4418959
CAS :<p>GSK4418959 (IDE275) is a selective WRN helicase inhibitor that blocks ATPase and DNA unwinding, serving as a tool in MSI-H cancer research.</p>Formule :C31H30F4N4O5SDegré de pureté :99.141%Couleur et forme :SoildMasse moléculaire :646.65VVD-214
CAS :<p>VVD-214 (RO7589831) is a WRN deconjugation enzyme lethal-mutagenic inhibitor that can be used to study proliferative diseases.</p>Formule :C20H21F2N3O4SDegré de pureté :99.24%Couleur et forme :SoildMasse moléculaire :437.46Linvoseltamab
CAS :<p>Linvoseltamab, a bispecific antibody, targets both BCMA (TNFRSF17) and CD3 epsilon, demonstrating a favorable safety profile and promising efficacy in relapsed/</p>Couleur et forme :LiquidFlotetuzumab
CAS :<p>Flotetuzumab (MGD006/S80880) is a CD123/CD3 bispecific DART antibody, reactivating T-cells for AML treatment.</p>Couleur et forme :LiquidTepoditamab
CAS :<p>Tepoditamab (MCLA-117) is a bispecific antibody targeting CLEC12A and CD3, inducing T cell lysis of AML cells.</p>Couleur et forme :LiquidD-F07
CAS :<p>D-F07 is a novel fluorescent IRE-1 RNase inhibitor and a tricyclic chromone with potential anticancer activity.</p>Formule :C18H21NO6Degré de pureté :98.31% - 99.31%Couleur et forme :SoildMasse moléculaire :347.36SB273005
CAS :<p>SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.</p>Formule :C22H24F3N3O4Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :451.442'-Azido-2'-deoxyuridine
CAS :<p>2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor with anti-cancer activity.</p>Formule :C9H11N5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :269.21hDHODH-IN-2
CAS :<p>hDHODH-IN-2: Leflunomide metabolite analog, inhibits human dihydroorotate dehydrogenase, anti-inflammatory.</p>Formule :C19H16N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :304.349E-982
CAS :<p>E-982 is derived from the reference compound.</p>Formule :C25H31NO6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.58Mirvetuximab soravtansine
CAS :<p>Mirvetuximab soravtansine (IMGN853) is an antibody-drug coupling that targets FRα, inhibits cell growth, and can be used to study drug-resistant ovarian cancer</p>Degré de pureté :6mg/ml - 6mg/mlCouleur et forme :LiquidMasse moléculaire :150000 (average)Adenosine 2'-PEG-Biotin
CAS :<p>Adenosine 2'-PEG-Biotin, a bioreagent derived from adenosine, modulates cellular signaling pathways by mimicking the action of endogenous adenosine and binding to its receptors. This compound is used in research related to bioprobes, biosensors, and diagnostic agents.</p>Formule :C26H40N8O8SCouleur et forme :SolidMasse moléculaire :624.71RI(dl)-2 TFA
CAS :RI(dl)-2 TFA inhibits RAD51 D-loop at 11.1 μM and HR in human cells at 3.0 μM.Formule :C19H17N3Couleur et forme :SolidMasse moléculaire :287.36L-Threonolactone
CAS :<p>L-Threonolactone is a Carbohydrate Derivative.</p>Formule :C4H6O4Couleur et forme :SolidMasse moléculaire :118.09(R)-(+)-O-Demethylbuchenavianine
CAS :<p>(R)-(+)-O-Demethylbuchenavianine is a cyclin-dependent kinase (CDK) inhibitor. It inhibits CDK1, CDK5, glycogen synthase kinase 3 (GSK3), cdc2-like kinase (CLK1), and dual-specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) with IC50 values of 1.1 μM, 0.95 μM, >10 μM, >10 μM, and >10 μM, respectively.</p>Formule :C21H21NO4Couleur et forme :SolidMasse moléculaire :351.40XL413
CAS :<p>XL-413 is an oral CDC7 kinase inhibitor, potentially blocking DNA replication, mitosis, and cancer cell growth.</p>Formule :C14H12ClN3O2Degré de pureté :98.40% - >99.99%Couleur et forme :SolidMasse moléculaire :289.72BAY1217389
CAS :<p>BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).</p>Formule :C27H24F5N5O3Degré de pureté :98.14% - 99.42%Couleur et forme :SolidMasse moléculaire :561.5Tirofiban
CAS :<p>Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.</p>Formule :C22H36N2O5SDegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :440.6
