Enzyme
Les inhibiteurs d'enzymes sont des molécules qui se lient aux enzymes et diminuent leur activité. Ces inhibiteurs sont largement utilisés en recherche pour étudier la cinétique enzymatique, la régulation et le rôle spécifique des enzymes dans les voies métaboliques. Les inhibiteurs d'enzymes sont également cruciaux dans le développement de médicaments, car de nombreux agents thérapeutiques agissent en inhibant les enzymes impliquées dans les processus pathologiques. En ciblant les enzymes, ces inhibiteurs peuvent moduler les voies biochimiques et offrir des traitements potentiels pour diverses maladies. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs d'enzymes de haute qualité pour soutenir vos recherches en biochimie, pharmacologie et découverte de médicaments.
Sous-catégories appartenant à la catégorie "Enzyme"
- Anhydrase carbonique(196 produits)
- Hydroxylase(36 produits)
- MPO(2 produits)
- Réductase(51 produits)
- Tyrosinase(71 produits)
3619 produits trouvés pour "Enzyme"
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Tioxolone
CAS :Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.Formule :C7H4O3SDegré de pureté :97.79%Couleur et forme :Light Yellow To Beige PowderMasse moléculaire :168.17Arbutin
CAS :Arbutin, a bearberry extract, blocks melanin by inhibiting tyrosinase.Formule :C12H16O7Degré de pureté :99.58% - 99.93%Couleur et forme :Colorless Elongated Prisms From Moist Ethyl Acetate White PowderMasse moléculaire :272.25Actarit
CAS :Actarit (4-acetylaminophenylacetic acid) is an anti-inflammatory drug.Formule :C10H11NO3Degré de pureté :99.64% - 99.74%Couleur et forme :White Or Off-White Crystal Or Crystalline SolidMasse moléculaire :193.2Benzthiazide
CAS :Benzthiazide treats edema and hypertension by promoting diuresis and inhibiting kidney Na+/Cl- reuptake, but may reduce potassium and raise uric acid.
Formule :C15H14ClN3O4S3Degré de pureté :99.34% - 99.79%Couleur et forme :Crystals From Acetone SolidMasse moléculaire :431.94Topiramate
CAS :Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.Formule :C12H21NO8SDegré de pureté :99.79% - 99.92%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :339.36pNNP
CAS :pNNP is a substrate for PP2C assays and inhibits β-carbonic anhydrase, α-carbonate dehydrogenase, and H. pylori.Formule :C6H6NO6PDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :219.09Brinzolamide
CAS :Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.Formule :C12H21N3O5S3Degré de pureté :99.84% - >99.99%Couleur et forme :Crystalline SolidMasse moléculaire :383.51Fenclonine
CAS :Fenclonine (CP-10188) is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin.Formule :C9H10ClNO2Degré de pureté :98.81% - >99.99%Couleur et forme :Crystals From Methanol White SolidMasse moléculaire :199.63Acipimox
CAS :Acipimox (K-9321), a niacin derivative, treats hyperlipidemia in type 2 diabetics.Formule :C6H6N2O3Degré de pureté :98.98%Couleur et forme :Low Yellow Liquid Or CrystallineMasse moléculaire :154.12Telotristat ethyl
CAS :Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.Formule :C27H26ClF3N6O3Degré de pureté :98% - 99.89%Couleur et forme :White SolidMasse moléculaire :574.98Flanvotumab
CAS :Flanvotumab (IMC-20D7S) is a humanized antibody targeting TYRP1 with strong antitumor effects via NK cells and ADCC.Degré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :145.42 kDaACT-678689
CAS :ACT-678689 (Compound Example 1.53.4) (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1].Formule :C23H22ClFN6O4S2Degré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :565.04Ref: TM-T14119
1mg107,00€5mg245,00€10mg371,00€25mg620,00€50mg858,00€100mg1.153,00€200mg1.549,00€1mL*10mM (DMSO)308,00€Zonisamide
CAS :Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures.Formule :C8H8N2O3SDegré de pureté :99.05% - 99.9%Couleur et forme :Off-White PowderMasse moléculaire :212.23p-Ethynylphenylalanine hydrochloride
CAS :p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent and specific inhibitor of TPH[1].Formule :C11H12ClNO2Degré de pureté :99.03%Couleur et forme :SolidMasse moléculaire :225.675-Feruloylquinic acid
CAS :5-Feruloylquinic acid, a potent Sirt1 activator, may aid in developing anti-aging drugs.Formule :C17H20O9Degré de pureté :99.03%Couleur et forme :SolidMasse moléculaire :368.34Methazolamide
CAS :Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.Formule :C5H8N4O3S2Degré de pureté :99.31% - 99.77%Couleur et forme :Crystals From Water SolidMasse moléculaire :236.27KW-2450 Formate
KW-2450 Formate is an IGF-1R/IR tyrosine kinase inhibitor with antitumor effects that acts through inhibition of Aurora A and B kinases.KW-2450 Formate inhibits the growth of TNBC xenografts and induces tetraploid accumulation.Formule :C29H31N5O5SDegré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :561.65Methocarbamol
CAS :Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.Formule :C11H15NO5Degré de pureté :99.96%Couleur et forme :Crystals From Benzene SolidMasse moléculaire :241.24Carbonic anhydrase inhibitor 31
Carbonic anhydrase inhibitor31 is an mtCA2 inhibitor (Ki: 5.2 nM) that can be used in antituberculosis research.Formule :C24H20N6O5SCouleur et forme :SolidMasse moléculaire :504.12159hCAIX/XII-IN-14
hCAIX/XII-IN-14 (Compound 1i) is an inhibitor of hCAIX and hCAXII, with Ki values of 9.4 nM for hCAII, 5.6 nM for hCAIX, and 6.3 nM for hCAXII.Formule :C16H14F3N3O4SCouleur et forme :SolidMasse moléculaire :401.36hCAIX-IN-17
hCA IX-IN-1 inhibits hCA I/II/IX/XII with Ki of 331.4/28.4/9.4/17.8 nM, has anticancer properties.Formule :C19H18N2O3SCouleur et forme :SolidMasse moléculaire :354.42α-Amylase, liquid
CAS :Degré de pureté :≥ 20,000U/gCouleur et forme :Brown liquidMasse moléculaire :-Carbonic anhydrase inhibitor 30
Carbonic anhydrase inhibitor30 (compound 17) is an inhibitor of carbonic anhydrase with Ki values of 2.13 μM for hCA I and 0.161 μM for hCA II[1].Formule :C23H22FN3O5SCouleur et forme :SolidMasse moléculaire :471.12642Trypsin
CAS :Degré de pureté :≥ 250IU/mgCouleur et forme :White to off-white powderMasse moléculaire :-hCA/VEGFR-2-IN-2
Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII andFormule :C23H26N6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :498.55CAIX Inhibitor S4
CAS :CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.
Formule :C15H17N3O4SDegré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :335.38Lysozyme, from chicken egg white
CAS :Degré de pureté :≥ 20,000U/mgCouleur et forme :White to off-white powderMasse moléculaire :-Glucose Oxidase
CAS :Degré de pureté :≥ 100U/mgCouleur et forme :Pale yellow to dark yellow powderMasse moléculaire :-P-Hydroxybenzoate Hydroxylase
CAS :Couleur et forme :Yellowish lyophilised powderMasse moléculaire :55 ~ 60 kDaHyaluronidase
CAS :Degré de pureté :≥ 300U/mgCouleur et forme :White to yellow powderMasse moléculaire :-Acesulfame
CAS :Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.Formule :C4H5NO4SCouleur et forme :SolidMasse moléculaire :163.15β-Glucosidase, from almonds
CAS :Degré de pureté :approx. 90% (biuret)Couleur et forme :White to pale yellow or beige powderMasse moléculaire :-Tyrosinase-IN-36
Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.Couleur et forme :Odour SolidDorzolamide
CAS :Dorzolamide is an anti-glaucoma agent and is a carbonic anhydrase inhibitor.
Formule :C10H16N2O4S3Degré de pureté :98%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :324.44Pyrocatechol
CAS :Pyrocatechol, often known as catechol or benzene-1,2-diol, is a benzenediol, Pyrocatechol was produced at a large scale industrially, mainly as precursors to pesticides, flavors, and fragrances. Its sulfonic acid is often present in the urine of many mammals.Formule :C6H6O2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :110.11CAIX/CAXII-IN-3
CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.Couleur et forme :Odour SolidCAIX/CAXII-IN-4
CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.Formule :C23H21N5O3SCouleur et forme :SolidMasse moléculaire :447.51hCA/VEGFR-2-IN-4
hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/Formule :C22H23FN6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.52TPH1-IN-1
TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.Formule :C21H18N6O4SCouleur et forme :SolidMasse moléculaire :450.47hCAIX-IN-19
hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/Couleur et forme :Odour SolidCarbonic anhydrase inhibitor 32
Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.Formule :C17H16N6O3SCouleur et forme :SolidMasse moléculaire :384.412-Methoxy-4-propylphenol
CAS :2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.
Formule :C10H14O2Couleur et forme :SolidMasse moléculaire :166.22Proteinase K
CAS :Degré de pureté :≥ 30units/mg (pH 7.5, 37°C, dried basis)Couleur et forme :White or almost white lyophilized powderMasse moléculaire :-Peroxidase, from horseradish, approx. 200 U/mg
CAS :Degré de pureté :≥ 150U/mgCouleur et forme :Beige to light-brown, reddish brown or dark brown lyophilised powderMasse moléculaire :-Tyrosinase-IN-32
Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.Formule :C15H19NO3Couleur et forme :SolidMasse moléculaire :261.32Tyrosinase-IN-34
Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.Formule :C19H14BrClN4OCouleur et forme :SolidMasse moléculaire :429.7β-Amylase, from soy
CAS :Degré de pureté :≥ 10.0units/mgCouleur et forme :White to off-white powderMasse moléculaire :-VM4-037
CAS :VM4-037 is a PET imaging agent used for carbonic anhydrase IX.Formule :C26H29FN6O7S2Couleur et forme :SolidMasse moléculaire :620.67Pseudostellarin G
CAS :Pseudostellarin G, a naturally occurring cyclo-octapeptide, exhibits inhibitory activity against tyrosinase and suppresses melanin production.Formule :C42H56N8O9Couleur et forme :SolidMasse moléculaire :816.94TPT-004
TPT-004, a TPH inhibitor, exhibits superior pharmacokinetic and pharmacodynamic properties, and demonstrates efficacy in preclinical models for attenuatingCouleur et forme :Odour SolidDPP IV/hCA II-IN-1
CAS :DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).
Formule :C17H20N2O5SCouleur et forme :SolidMasse moléculaire :364.42Xanthine Oxidase, ammonium sulfate suspension
CAS :Couleur et forme :Faint brown to dark brown suspensionIOX2-NH2-1
CAS :IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.Formule :C19H17N3O5Degré de pureté :98.77% - 99.91%Couleur et forme :SoildMasse moléculaire :367.36hCAII-IN-6
"hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."Formule :C20H25N3O4SCouleur et forme :SolidMasse moléculaire :403.5Calmodulin-dependent Protein Kinase II fragment 290-309
CAS :Formule :C103H185N31O24SMasse moléculaire :2273.83hCAII-IN-7
hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.Formule :C20H25N3O4SCouleur et forme :SolidMasse moléculaire :403.5Phenylsulfamide
CAS :Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and anFormule :C6H8N2O2SCouleur et forme :SolidMasse moléculaire :172.2Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS :Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effectFormule :C47H64N14O10Couleur et forme :SolidMasse moléculaire :985.1hCAII-IN-8
CAS :Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.Formule :C15H16N2O5SDegré de pureté :99.73%Couleur et forme :SoildMasse moléculaire :336.36Ref: TM-T67774
5mg42,00€10mg64,00€25mg116,00€50mg167,00€100mg241,00€200mg339,00€1mL*10mM (DMSO)52,00€Chlorothiazide
CAS :Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.Formule :C7H6ClN3O4S2Degré de pureté :98.46% - 98.91%Couleur et forme :Crystals Physical Description Crystals; White Powder (Ntp 1992)Masse moléculaire :295.72Carbonic anhydrase inhibitor 29
Carbonic anhydrase inhibitor29 (Compound 5d) is an inhibitor targeting carbonic anhydrase IX and XII, with an inhibition constant (Ki) of 26.6 nM for carbonic anhydrase IX and a Ki of 10.9 nM for carbonic anhydrase XII. Carbonic anhydrase inhibitor29 can be used in cancer research.Couleur et forme :Odour SolidPeroxidase
CAS :Degré de pureté :≥ 85units/mg (dry basis)Couleur et forme :Beige to light-brown, reddish brown or dark brown lyophilised powderMasse moléculaire :-TSPO/Carbonic Anhydrase Modulator 1
TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) acts as a dual modulator of mitochondrial translocator protein and carbonic anhydrase, with a TSPOKi of 1.340 μM and a CAVII KA of 10.7 μM. It enhances neurosteroid production, increases BDNF gene expression, and demonstrates neuroprotective activity.Formule :C35H51N3O3Couleur et forme :SolidMasse moléculaire :561.798Trypsin, bovine origin
CAS :Degré de pureté :≥ 2000units/mg (USP)Couleur et forme :White or almost white crystalline powderMasse moléculaire :-Tyrosinase-IN-38
Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.Couleur et forme :Odour Solid(E)-Dehydrodiconiferyl alcohol
CAS :(E)-Dehydrodiconiferyl alcohol inhibits hCA IX/XII enzymes and blocks NF-κB nuclear translocation in healing tissues.Formule :C20H22O6Couleur et forme :SolidMasse moléculaire :358.39DOTA-XYIMSR-01
CAS :DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.Formule :C61H88N16O22S2Couleur et forme :SolidMasse moléculaire :1461.575,6-Dihydro-2H-pyran-2-one
CAS :5,6-Dihydro-2H-pyran-2-one is a carbonic anhydrase 1/9 inhibitor that inhibits KB cell viability.Formule :C5H6O2Couleur et forme :SolidMasse moléculaire :98.1CAXII-IN-2
CAXII-IN-2 (compound 3j) is a highly effective inhibitor of CAXII. It demonstrates inhibitory activity against CA IX and CAXII, with Ki values of 27.4 nM and 4.0 nM, respectively.Formule :C16H13FNO4PCouleur et forme :SolidMasse moléculaire :333.05662
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