Transporteur membranaire/Canal ionique

Les inhibiteurs des transporteurs membranaires et des canaux ioniques sont des composés qui bloquent la fonction des protéines responsables du transport des ions, des nutriments et d'autres molécules à travers les membranes cellulaires. Ces inhibiteurs sont essentiels pour étudier la régulation de l'homéostasie cellulaire, la transduction des signaux et la neurotransmission. Les inhibiteurs des transporteurs membranaires et des canaux ioniques sont également importants pour développer des traitements contre des troubles tels que l'épilepsie, les maladies cardiovasculaires et les syndromes métaboliques. Chez CymitQuimica, nous offrons une sélection diversifiée d'inhibiteurs de haute qualité des transporteurs membranaires et des canaux ioniques pour soutenir vos recherches en physiologie, neurosciences et pharmacologie.

Sous-catégories appartenant à la catégorie "Transporteur membranaire/Canal ionique"

Affichez 13 plus de sous-catégories

2270 produits trouvés pour "Transporteur membranaire/Canal ionique"

Trier par

Tri par prix ascendantTri par prix descendantPuretés inférieures en premierPuretés supérieures en premierLivraison estimée la plus rapide en premier

Degré de pureté (%)

100

produits par page.

+ Info
Emamectin B1a
CAS :
- 121124-29-6
Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.
Formule :C₄₉H₇₅NO₁₃
Couleur et forme :Solid
Masse moléculaire :886.133
Ref: TM-T37663
+ Info
GDC-0334
CAS :
- 1984824-54-5
GDC-0334 is a TRPA1 antagonist useful in treatment TRPA1-mediated diseases, such as pain or asthma.
Formule :C₂₄H₁₉F₈N₅O₃S
Couleur et forme :Solid
Masse moléculaire :609.5
Ref: TM-T39408
+ Info
Bendroflumethiazide
CAS :
- 73-48-3
Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
Formule :C₁₅H₁₄F₃N₃O₄S₂
Degré de pureté :98% - >99.99%
Couleur et forme :Crystals From Dioxane Solid
Masse moléculaire :421.41
Ref: TM-T1204
+ Info
3-Aminopropylphosphonic Acid
CAS :
- 13138-33-5
3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding
Formule :C₃H₁₀NO₃P
Degré de pureté :99.84%
Couleur et forme :Light Yellow Liquid
Masse moléculaire :139.09
Ref: TM-T38205
+ Info
Way 125971
CAS :
- 139047-48-6
Way 125971 is a bioactive chemcial.
Formule :C₂₂H₂₈N₄O₅S₂
Couleur et forme :Solid
Masse moléculaire :492.61
Ref: TM-T35111
+ Info
(R)-Funapide
CAS :
- 1259933-15-7
(R)-Funapide ((R)-TV 45070), the less active R-enantiomer of Funapide, acts as a potent Nav1.7 sodium channel blocker, primarily utilized in pain research [1].
Formule :C₂₂H₁₄F₃NO₅
Couleur et forme :Solid
Masse moléculaire :429.35
Ref: TM-T75250
+ Info
SLC6A8 corrector 1
SLC6A8 Corrector 1 is an orally active corrector for mutant SLC6A8 variants, capable of crossing the blood-brain barrier. It is utilized in the study of creatine transporter deficiency (CTD).
Formule :C₂₁H₂₅N₃O₂
Couleur et forme :Solid
Masse moléculaire :351.44
Ref: TM-T201220
+ Info
Iberiotoxin
CAS :
- 129203-60-7
Selective blocker of the big conductance Ca2+-activated K+ channel.
Formule :C₁₇₉H₂₇₄N₅₀O₅₅S₇
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :4230
Ref: TM-TP2014
+ Info
GaTx2
CAS :
- 194665-85-5
High-affinity ClC-2 blocker (KD ~50 pM), selective over other ClCs/CFTR/GABAC/CaCC/KV1.2; slows activation, no effect on open channels.
Formule :C₁₂₅H₁₉₉N₃₉O₄₇S₆
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :3192.54
Ref: TM-TP2027
+ Info
Huwentoxin-IV
CAS :
- 526224-73-7
Selective NaV1.7 blocker; also inhibits NaV1.2, 1.3; less effect on NaV1.4, 1.5. Binds to neurotoxin site, traps voltage sensor. IC50: 26-338 nM.
Formule :C₁₇₄H₂₇₈N₅₂O₅₁S₆
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :4106.79
Ref: TM-TP2016
+ Info
OD1
Activates rat Nav1.7, human Nav1.4, rat Nav1.6 (EC50: 7, 10, 47 nM); minimal on Nav1.2, 1.3, 1.5 (EC50 >3 μM); blocks fast inactivation; triggers pain.
Formule :C₃₀₈H₄₆₆N₉₀O₉₅S₈
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :7206.1
Ref: TM-TP1972
+ Info
GluN2B-NMDAR antagonist-1
Orally active GluN2B-NMDAR antagonist with neuroprotective properties for ischemic injury research.
Formule :C₂₆H₂₃BrN₂O₂
Couleur et forme :Solid
Masse moléculaire :475.38
Ref: TM-T74854
+ Info
Idactamab
CAS :
- 2245205-37-0
Idactamab (INT-001) is a monoclonal antibody to the human amino acid transport protein ASCT2.
Degré de pureté :> 95%
Couleur et forme :Liquid
Masse moléculaire :146.2 kDa
Ref: TM-T77385
+ Info
AZD-3161
CAS :
- 1369501-46-1
AZD-3161 is a sodium channel regulator for pain.
Formule :C₂₃H₂₁F₃N₄O₄
Couleur et forme :Solid
Masse moléculaire :474.43
Ref: TM-T30256
+ Info
TRPV1 activator-1
CAS :
- 1803181-80-7
TRPV1 Activator-1 (Compound 8), a capsaicin analog featuring a modified neck structure, specifically interacts with the T551 residue [1].
Formule :C₁₈H₂₇NO₂S
Couleur et forme :Solid
Masse moléculaire :321.48
Ref: TM-T74741
+ Info
MRS4596
MRS4596: selective P2X4 blocker, IC50 1.38 μM, neuroprotective in stroke research.
Formule :C₂₁H₁₄N₅NaO₃S
Couleur et forme :Solid
Masse moléculaire :439.42
Ref: TM-T73452
+ Info
PDZ1 Domain inhibitor peptide
CAS :
- 1315378-73-4
Novel cyclic peptide that disrupts interaction between GluR6 and PSD-95
Formule :C₃₈H₆₁N₉O₁₁
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :819.94
Ref: TM-TP2208
+ Info
(R)-Lanicemine
CAS :
- 190581-71-6
(R)-Lanicemine ((R)-AZD6765), an R-enantiomer with less activity, is a low-trapping NMDA blocker with antidepressant effects.
Formule :C₁₃H₁₄N₂
Couleur et forme :Solid
Masse moléculaire :198.26
Ref: TM-T73682
+ Info
AChE/Aβ-IN-2
AChE/Aβ-IN-2 (compound 33) is a powerful, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 135 nM.
Formule :C₂₀H₂₅ClN₄
Couleur et forme :Solid
Masse moléculaire :356.89
Ref: TM-T79571
+ Info
Digoxigenin Monodigitoxoside
CAS :
- 5352-63-6
Digoxigenin monodigitoxoside is a cardiac glycoside metabolite of digoxin and a Na+/K+ ATPase inhibitor.
Formule :C₂₉H₄₄O₈
Couleur et forme :Solid
Masse moléculaire :520.663
Ref: TM-T36060
+ Info
NT 13
CAS :
- 117928-93-5
NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and other related diseases.
Formule :C₁₈H₃₀N₄O₇
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :414.45
Ref: TM-TP1023
+ Info
sFTX-3.3
CAS :
- 141997-14-0
sFTX-3.3 is a calcium ion channel antagonist, exhibiting IC50 values of approximately 0.24 mM and 0.70 mM against P-type and N-type channels respectively.
Formule :C₁₂H₂₉N₇O
Couleur et forme :Solid
Masse moléculaire :287.412
Ref: TM-T38854
+ Info
8-Bromo-ATP
CAS :
- 23567-97-7
8-Bromo-ATP (8-Bromoadenosine 5'-triphosphate) is a purinergic P2X receptor agonist and an ATP analogue.
Formule :C₁₀H₁₅BrN₅O₁₃P₃
Couleur et forme :Solid
Masse moléculaire :586.077
Ref: TM-T39891
+ Info
JYL-79
CAS :
- 289902-64-3
JYL-79 is an agonist of the vanilloid receptor.
Formule :C₂₆H₃₆N₂O₄S
Couleur et forme :Solid
Masse moléculaire :472.64
Ref: TM-T24237
+ Info
Nipecotic acid
CAS :
- 498-95-3
Compound PDK0243, with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0243 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.
Formule :C₆H₁₁NO₂
Couleur et forme :Off-White To Pale Yellow-Beige Powder
Masse moléculaire :129.16
Ref: TM-PDK0243
+ Info
P-gp inhibitor 13
P-gp Inhibitor 13, a P-glycoprotein antagonist, can counteract paclitaxel resistance in A2780/T cells, proving valuable for advanced acute myeloid leukemia
Formule :C₃₂H₃₄O₈
Couleur et forme :Solid
Masse moléculaire :546.61
Ref: TM-T78974
+ Info
ADWX 1
Potent KV1.3 blocker, IC50: 0.0019 nM; less effective on KV1.1. Curbs CD4+ T cell activation; eases rat multiple sclerosis model.
Formule :C₁₆₉H₂₈₁N₅₇O₄₆S₇
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :4071.86
Ref: TM-TP2080
+ Info
CHET3
CAS :
- 2489231-47-0
CHET3 is a highly selective allosteric activator for TASK-3-containing K2P channels. CHET3 has shown potent in vivo analgesic effects. Cost-effective and quality-assured.
Formule :C₂₁H₂₁N₅O₃S
Degré de pureté :99.64% - >99.99%
Couleur et forme :Soild
Masse moléculaire :423.49
Ref: TM-T72066
+ Info
Lyso-Globotriaosylceramide (d18:1)
CAS :
- 126550-86-5
Lyso-Gb3, lacking fatty acyl, binds Stx1 with cholesterol and phosphatidylcholine, not Stx2; lowers neutrophil viability; accumulates in Fabry disease.
Formule :C₃₆H₆₇NO₁₇
Couleur et forme :Solid
Masse moléculaire :785.922
Ref: TM-T37291
+ Info
Anticancer agent 108
Anticancer Agent 108 (Compound 3.10) serves as a potent P-gp inhibitor exhibiting considerable antitumor properties while maintaining reduced toxicity to both
Formule :C₁₈H₉NO₅S₂
Couleur et forme :Solid
Masse moléculaire :383.4
Ref: TM-T78693
+ Info
Mutabilol
Mutabilol boosts P-gp in NCI-H460/R cells; natural from Plectranthus mutabilis.
Formule :C₁₉H₂₄O₅
Couleur et forme :Solid
Masse moléculaire :332.39
Ref: TM-T75524
+ Info
Mesoridazine free base
CAS :
- 5588-33-0
Mesoridazine (thioridazine EP impurity B) is a phenothiazine antipsychotic with effects similar to chlorpromazine.
Formule :C₂₁H₂₆N₂OS₂
Couleur et forme :Solid
Masse moléculaire :386.57
Ref: TM-T3086L
+ Info
Neurotransmitter Receptor Compound Library
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；
Couleur et forme :Odour Solid
Ref: TM-L2610
+ Info
GpTx-1 TFA
GpTx-1 TFA is a polypeptide NaV1.7 sodium channel antagonist isolated from the venom of the Chilean spider Grammostola porter. It exhibits potent inhibitory activity on the NaV1.7 channel with an IC50 value of 10 nM, demonstrating excellent selectivity over NaV1.4 (IC50 = 0.301 μM) and NaV1.5 (IC50 = 4.20 μM) with >20-fold and >950-fold selectivity, respectively.
Couleur et forme :Odour Solid
Ref: TM-TP3232
+ Info
D-GsMTx4
TRPC1/6 & Piezo2 inhibitor; mimics GsMTx4; blocks ~70% mechanosensitive currents; aids in mouse heart attack models; protease-resistant.
Couleur et forme :Soild
Ref: TM-T37697
+ Info
AQP3-IN-1
CAS :
- 198711-19-2
AQP3-IN-1 (compounds 3), an AQP3 inhibitor, exhibits an IC 50 of 8.91 μM and effectively inhibits melanoma cell proliferation [1].
Formule :C₁₁H₉AuCl₂N₂
Couleur et forme :Solid
Masse moléculaire :437.08
Ref: TM-T85716
+ Info
CPI1
CPI1 is an effective and highly specific inhibitor of multidrug resistance protein 1 (MRP1). It exhibits inhibitory activity against MRP1 at the nanomolar level (Ki: 100 nM) and has minimal effect on P-glycoprotein (Pgp). CPI1 competes with LTC4 for binding to the same site on MRP1, inhibiting ATP hydrolysis and substrate transport. It is useful in research related to drug delivery and addressing cancer chemotherapy resistance.
Formule :C₁₁₁H₁₃₁N₂₃O₃₀S
Couleur et forme :Solid
Masse moléculaire :2299.43
Ref: TM-TP3085
+ Info
Dendrotoxin K
CAS :
- 119128-61-9
Dendrotoxin K blocks Kv1.1 channels, modulating glutamate release in CA3 neurons by controlling presynaptic spike timing.
Formule :C₂₉₄H₄₆₂N₈₄O₇₅S₆
Couleur et forme :Solid
Masse moléculaire :6559.66
Ref: TM-T76187
+ Info
Ethacrynic acid D5
CAS :
- 1330052-59-9
Ethacrynic acid: a diuretic, anti-inflammatory, inhibits calcium channels, GSTs, NF-kB pathway, and modulates leukotriene; has deuterium-labeled form.
Formule :C₁₃H₁₂Cl₂O₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :308.17
Ref: TM-T11240
+ Info
Atelopidtoxin
CAS :
- 9061-57-8
Atelopidtoxin is a biochemical.
Formule :C₁₆H₂₄N₈O₁₂S
Couleur et forme :Solid
Masse moléculaire :552.47
Ref: TM-T30193
+ Info
(1S,3R)-3-Aminocyclopentane carboxylic acid
CAS :
- 71830-07-4
(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.
Formule :C₆H₁₁NO₂
Couleur et forme :Solid
Masse moléculaire :129.16
Ref: TM-T203289
+ Info
CP-628006
CAS :
- 305822-08-6
CP-628006 is a small molecule CFTR potentiator that effectively restores ATP-dependent channel gating to G551D-CFTR, the mutant form found in cystic fibrosis.
Formule :C₃₂H₃₅F₃N₂O₂
Couleur et forme :Solid
Masse moléculaire :536.639
Ref: TM-T40386
+ Info
Crocetin meglumine
Crocetin (Transcrocetin) meglumine, sourced from Crocus sativus L. (saffron), functions as a high-affinity antagonist of the NMDA receptor.
Formule :C₃₄H₅₈N₂O₁₄
Couleur et forme :Solid
Masse moléculaire :718.83
Ref: TM-T75267
+ Info
(±)8(9)-EpETE
CAS :
- 851378-93-3
(±)8(9)-EpETE ((±)8,9-EEQ) is an epoxide of arachidonic acid biosynthesized by CYP450 epoxygenase.1.2 In rat and rabbit liver microsomes.
Formule :C₂₀H₃₀O₃
Couleur et forme :Solid
Masse moléculaire :318.45
Ref: TM-T37228
+ Info
Brevetoxin-3
CAS :
- 85079-48-7
Brevetoxin-3 activates Na+ channels, binding strongly to site 5, preventing their inactivation.
Formule :C₅₀H₇₂O₁₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :897.112
Ref: TM-T10609
+ Info
Jingzhaotoxin-XII TFA
Jingzhaotoxin-XII (JzTx-XII) TFA is a specific inhibitor of the Kv4.1 channel, exhibiting an IC50 of 0.363 μM. It interacts with the channel by altering gating behavior.
Couleur et forme :Odour Solid
Ref: TM-TP2888
+ Info
Phrixotoxin 3
CAS :
- 880886-00-0
Potent NaV blocker: IC50 - 0.6 nM (NaV1.2), 42 nM (NaV1.3), 72 nM (NaV1.5); voltage-dependent inhibition.
Formule :C₁₇₆H₂₆₉N₅₁O₄₈S₆
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :4059.74
Ref: TM-TP1967
+ Info
Nitrazolam
CAS :
- 28910-99-8
Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.
Formule :C₁₇H₁₃N₅O₂
Couleur et forme :Solid
Masse moléculaire :319.32
Ref: TM-T203627
+ Info
Transdermal Peptide Disulfide
CAS :
- 888486-23-5
TD 1 peptide, an 11-amino acid, binds ATP1B1's C-terminus, enhancing transdermal drug delivery.
Formule :C₄₀H₆₄N₁₄O₁₆S₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :1061.15
Ref: TM-TP1033
+ Info
Tiludronate disodium hemihydrate
CAS :
- 155453-10-4
Tiludronate: an oral bisphosphonate for bone disorder research; inhibits osteoclasts and reduces inflammation.
Formule :C₁₄H₁₆Cl₂Na₄O₁₃P₄S₂
Couleur et forme :Solid
Masse moléculaire :743.16
Ref: TM-T39037
+ Info
ω-Agatoxin TK
CAS :
- 158484-42-5
Selective blocker of CaV2.1 P/Q-type calcium channels.
Formule :C₂₁₅H₃₃₇N₆₅O₇₀S₁₀
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :5273.02
Ref: TM-TP2088
+ Info
4'-hydroxy Trazodone
CAS :
- 53818-10-3
4’-hydroxy Trazodone is a metabolite of the antidepressant and sedative trazodone.1It is an inhibitor of organic anion transporter 3 (OAT3; Ki= 16.9 μM) and is
Formule :C₁₉H₂₂ClN₅O₂
Couleur et forme :Solid
Masse moléculaire :387.87
Ref: TM-T35721
+ Info
TRPV4 antagonist 3
CAS :
- 2681273-35-6
TRPV4 antagonist 3 is a TRPV4 antagonist (p IC 50 = 8.4).
Formule :C₂₀H₁₈F₄N₄O₃S
Couleur et forme :Solid
Masse moléculaire :470.44
Ref: TM-T40306
+ Info
AVLX-125
CAS :
- 1786434-31-8
AVLX-125 (UCCB01-125), a potent inhibitor of PSD-95 and PDZ domains, exhibits a dissociation constant (Kd) of 10 nM. It is utilized in researching inflammatory pain [1] [2].
Formule :C₆₂H₁₀₄N₁₀O₂₉
Couleur et forme :Solid
Masse moléculaire :1453.54
Ref: TM-TP2548
+ Info
Phe-Met-Arg-Phe, amide
CAS :
- 64190-70-1
Phe-Met-Arg-Phe amide activates K+ current in neurons (ED50=23 nM), co-localizes with neuropeptide Y in brain regions.
Formule :C₂₉H₄₂N₈O₄S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :598.76
Ref: TM-TP1858
+ Info
LTGO-33
CAS :
- 2834106-06-6
LTGO-33 is a voltage-gated sodium channel NaV1.8 inhibitor that inhibits NaV1.8, NaV1.1-NaV1.7, and NaV1.9.
Formule :C₂₁H₁₇F₄N₃O₃S
Degré de pureté :97.6%
Couleur et forme :Soild
Masse moléculaire :467.44
Ref: TM-T84298
+ Info
Tariquidar dimesylate
CAS :
- 625375-84-0
Tariquidar, a non-competitive P-glycoprotein inhibitor, may help combat cancer drug resistance.
Formule :C₈₀H₉₄N₈O₂₅S₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :1695.9
Ref: TM-T6287L
+ Info
epi-Aszonalenin A
CAS :
- 908853-14-5
epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.
Formule :C₂₅H₂₅N₃O₃
Couleur et forme :Solid
Masse moléculaire :415.48
Ref: TM-T74056
+ Info
LY-368975 hydrochloride
CAS :
- 222961-65-1
LY-368975 hydrochloride is a bioactive chemical.
Formule :C₁₇H₂₂ClNOS
Couleur et forme :Solid
Masse moléculaire :323.88
Ref: TM-T33015
+ Info
NAADP tetrasodium salt
CAS :
- 5502-96-5
Ca2+ mobilizing agent
Formule :C₂₁H₂₇N₆O₁₈P₃
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :744.39
Ref: TM-T23049
+ Info
Imagabalin
CAS :
- 610300-07-7
Imagabalin is an active compound used in the study of neurological diseases.
Formule :C₉H₁₉NO₂
Couleur et forme :Solid
Masse moléculaire :173.25
Ref: TM-T32143
+ Info
Chlorotoxin(linear)
Chlorotoxin(linear): 36-amino-acid peptide from Egyptian scorpion venom, used in research as chloride channel blocker.
Formule :C₁₅₈H₂₅₆N₅₂O₄₈S₁₁
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :4004.76
Ref: TM-TP1285
+ Info
TRPV1 activator-2
CAS :
- 17514-11-3
TRPV1 activator-2 (Compound 9), a capsaicin head analog, engages in targeted interactions with channel residues at the lipid-water interface [1].
Formule :C₁₉H₂₉NO₃
Couleur et forme :Solid
Masse moléculaire :319.44
Ref: TM-T74742
+ Info
PtdIns-(1,2-dioctanoyl) (sodium salt)
CAS :
- 899827-36-2
PtdIns phosphates, a minor membrane lipid fraction, are vital for cell signaling. Synthetic PtdIns-(1,2-dioctanoyl) has C8:0 fatty acids and high solubility.
Formule :C₂₅H₄₇NaO₁₃P
Couleur et forme :Solid
Masse moléculaire :609.602
Ref: TM-T36937
+ Info
P-gp inhibitor 27
P-gp inhibitor 27 (Compound D2) is an inhibitor of P-glycoprotein (P-gp) that reduces the expression of P-gp and MRP1. It increases the accumulation of Rh123 in A2780/T cells and reverses multidrug resistance to Paclitaxel (EC50 of 88 nM) and Cisplatin.
Formule :C₂₅H₂₅N₃O₄
Couleur et forme :Solid
Masse moléculaire :431.48
Ref: TM-T203146
+ Info
Withasomniferolide B
CAS :
- 2365386-75-8
Withasomniferolide B, a withanolide from Withania somnifera root, activates GABAA receptors.
Formule :C₂₈H₃₆O₄
Couleur et forme :Solid
Masse moléculaire :436.58
Ref: TM-T75557
+ Info
17R(18S)-EpETE
CAS :
- 725246-18-4
17R(18S)-EpETE: Oxylipin, eicosapentaenoic acid metabolite, activates BKCa channels, has negative chronotropic effects.
Formule :C₂₀H₃₀O₃
Couleur et forme :Solid
Masse moléculaire :318.457
Ref: TM-T36215
+ Info
Conantokin G TFA
Conantokin G TFA, a 17-aa peptide, blocks NMDA receptors with 480 nM IC50 and is neuroprotective.
Formule :C₉₀H₁₃₉F₃N₂₆O₄₆
Couleur et forme :Solid
Masse moléculaire :2378.21
Ref: TM-T75890
+ Info
Vanzacaftor
CAS :
- 2374124-49-7
Vanzacaftor is a CFTR modulator improving protein processing and surface trafficking, restoring chloride transport and aiding cystic fibrosis therapy research.
Formule :C₃₂H₃₉N₇O₄S
Degré de pureté :99.14%
Couleur et forme :Solid
Masse moléculaire :617.76
Ref: TM-T74417
+ Info
Idrevloride
CAS :
- 1416973-63-1
Idrevloride (WO2016133967) inhibits ENaC, used in skin disorder research.
Formule :C₃₀H₄₉ClN₈O₇
Couleur et forme :Solid
Masse moléculaire :669.22
Ref: TM-T38849
+ Info
ML353
ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.
Formule :C₁₉H₁₅FN₂O
Degré de pureté :99.98% - 99.98%
Couleur et forme :Soild
Masse moléculaire :306.33
Ref: TM-T67917
+ Info
(S)-JNJ-54166060
CAS :
- 1627900-42-8
(S)-JNJ-54166060, an enantiomer of JNJ-54166060, functions as a potent antagonist of P2X7 [1].
Formule :C₂₀H₁₅ClF₄N₄O
Couleur et forme :Solid
Masse moléculaire :438.81
Ref: TM-T73880
+ Info
Tenapanor HCl
CAS :
- 1234365-97-9
Tenapanor (AZD-1722, RDX 5791) inhibits NHE3 for sodium control in the gut and kidneys.
Formule :C₅₀H₆₈Cl₆N₈O₁₀S₂
Couleur et forme :Solid
Masse moléculaire :1217.97
Ref: TM-T7587L
+ Info
BDBM50597431
CAS :
- 1629853-49-1
BDBM50597431 is an NMDA receptor modulator that may have can be used to study Alzheimer's disease and Parkinson's syndrome.
Formule :C₂₇H₄₃F₃O₂
Degré de pureté :98.64% - 99.28%
Couleur et forme :Soild
Masse moléculaire :456.62
Ref: TM-T28367L1
+ Info
Homocarnosine TFA
Homocarnosine TFA: brain-exclusive GABA-histidine dipeptide, neuronal, anticonvulsant, antioxidant, anti-inflammatory.
Formule :C₁₂H₁₇F₃N₄O₅
Couleur et forme :Solid
Masse moléculaire :354.28
Ref: TM-T73818
+ Info
Tertiapin LQ
Kir1.1 channel blocker, 250x selective; Kd: Kir1.1 (1.1 nM), Kir3.1/3.2 (274 nM), Kir3.1/3.4 (361 nM). Tertiapin-Q derivative.
Formule :C₁₀₆H₁₇₉N₃₃O₂₄S₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :2428.03
Ref: TM-TP2113
+ Info
D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)
CAS :
- 210488-61-2
Ins(1,3,4,5)-P4, made via Ins(1,4,5)P3 phosphorylation, boosts calcium by opening ER and plasma membrane channels.
Formule :C₆H₈Na₈O₁₈P₄
Couleur et forme :Solid
Masse moléculaire :675.93
Ref: TM-T37058
+ Info
Antidepressant agent 4
Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.
Formule :C₁₉H₃₈ClN₅O₂S
Couleur et forme :Solid
Masse moléculaire :436.06
Ref: TM-T75003
+ Info
(±)5(6)-DiHETE
CAS :
- 845673-97-4
Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.
Formule :C₂₀H₃₂O₄
Couleur et forme :Solid
Masse moléculaire :336.472
Ref: TM-T37242
+ Info
18β-Glycyrrhetyl-3-O-sulfate
CAS :
- 10251-38-4
18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), serves as a potent inhibitor of type 2
Formule :C₃₀H₄₆O₇S
Couleur et forme :Solid
Masse moléculaire :550.75
Ref: TM-T74729
+ Info
MIDD0301
CAS :
- 2187489-08-1
MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.
Formule :C₁₉H₁₃BrFN₃O₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :414.23
Ref: TM-T9946
+ Info
Jingzhaotoxin III
CAS :
- 925463-91-8
NaV1.5 channels blocker
Formule :C₁₇₄H₂₄₁N₄₇O₄₆S₆
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :3919.47
Ref: TM-TP2263
+ Info
Withaphysalin D
CAS :
- 91599-21-2
Withaphysalin D, from water lilies, blocks GluN2B NMDARs and is neuroprotective, crossing the blood-brain barrier.
Formule :C₂₈H₃₄O₆
Couleur et forme :Solid
Masse moléculaire :466.57
Ref: TM-T75571
+ Info
Lifarizine FA
Lifarizine FA is a sodium channel blocker used in the treatment of neurological disorders and cardiovascular diseases, study of stroke.
Formule :C₃₀H₃₄N₄O₂
Degré de pureté :99.55%
Couleur et forme :Solid
Masse moléculaire :482.62
Ref: TM-T27830L
+ Info
24-Hydroxycholesterol
CAS :
- 30271-38-6
24-Hydroxycholesterol (Cholest-5-ene-3beta,24-diol) is an activator of the LXR and can be used to study cardiogenesis and pancreatic cancer.
Formule :C₂₇H₄₆O₂
Degré de pureté :99.8%
Couleur et forme :Solid
Masse moléculaire :402.65
Ref: TM-T10086
+ Info
6,7-dimethylisatin
CAS :
- 20205-43-0
6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.
Formule :C₁₀H₉NO₂
Degré de pureté :98.98%
Couleur et forme :Solid
Masse moléculaire :175.18
Ref: TM-T77568
+ Info
(R)-IDHP
CAS :
- 950665-05-1
(R)-IDHP, a salvia derivative, relaxes blood vessels by blocking calcium channels, aiding cardiovascular research.
Formule :C₁₂H₁₆O₅
Couleur et forme :Solid
Masse moléculaire :240.25
Ref: TM-T74193
+ Info
Sinapine hydroxide
CAS :
- 122-30-5
Sinapine hydroxide from crucifer seeds has anti-inflammatory, anti-oxidant, anti-tumor properties, and inhibits AChE, aiding neurodegenerative research.
Formule :C₁₆H₂₅NO₆
Couleur et forme :Solid
Masse moléculaire :327.377
Ref: TM-T38606
+ Info
Volixibat
CAS :
- 1025216-57-2
Volixibat, a selective inhibitor of the bile acid transporter, may treat non-alcoholic steatohepatitis.
Formule :C₃₈H₅₁N₃O₁₂S₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :805.95
Ref: TM-T17236
+ Info
(±)16-HETE
CAS :
- 128914-46-5
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.
Formule :C₂₀H₃₂O₃
Couleur et forme :Solid
Masse moléculaire :320.473
Ref: TM-T35465
+ Info
L-Ibotenic acid
CAS :
- 25690-45-3
L-Ibotenic acid: a psychoactive found in Amanita mushrooms, mimics glutamate, activates receptors.
Formule :C₅H₆N₂O₄
Couleur et forme :Solid
Masse moléculaire :158.11
Ref: TM-T25717
+ Info
AChE/Aβ-IN-1
AChE/Aβ-IN-1 (compound 32) is a potent, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 86 nM and an NMDA receptor antagonist targeting the
Formule :C₂₀H₂₅BrN₄
Couleur et forme :Solid
Masse moléculaire :401.34
Ref: TM-T79569
+ Info
LU-32-176B
CAS :
- 770688-66-9
LU32-176B is a bioactive chemical.
Formule :C₂₃H₂₄F₂N₂O₂
Couleur et forme :Solid
Masse moléculaire :398.45
Ref: TM-T32911
+ Info
Conantokin-R
CAS :
- 202925-60-8
Conantokin-R is an NMDA receptor peptide antagonist (IC50=93 nM); Conantokin-R exhibits anticonvulsant activity; Conantokin-R binds Zn2+ and Mg2+ (Kds 0.15 μM
Formule :C₁₂₇H₂₀₁N₃₅O₄₉S₃
Couleur et forme :Solid
Masse moléculaire :3098.38
Ref: TM-T38388
+ Info
Elgodipine
CAS :
- 119413-55-7
Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.
Formule :C₂₉H₃₃FN₂O₆
Degré de pureté :98.95% - 99.50%
Couleur et forme :Solid
Masse moléculaire :524.58
Ref: TM-T68060
+ Info
BMS 199264
CAS :
- 675833-20-2
BMS 199264 hydrochlorid a inhibitor of mitochondrial F1F0 ATP hydrolase, thus preventing ATP reduction to ameliorate cardiac necrosis during ischemia.
Formule :C₂₆H₃₁ClN₄O₄S
Degré de pureté :99.83%
Couleur et forme :Soild
Masse moléculaire :531.07
Ref: TM-T26843L
+ Info
S-WJM992
S-WJM992 (compound 10ahb) serves as an antiparasitic agent, effectively inhibiting ATPase activity in high [Na+] environments. It also significantly counteracts parasites resistant to PfATP4 inhibitors. Additionally, S-WJM992 acts as a potential transmission blocker by impeding gamete development and halting the transmission of parasites to mosquitoes during blood feeding.
Formule :C₂₂H₁₈ClFN₆O₃
Couleur et forme :Solid
Masse moléculaire :468.87
Ref: TM-T200205
+ Info
KCC2 potentiators-1
CAS :
- 3058906-46-7
Compound 2, known as KCC2 potentiators-1, acts as an enhancer of the potassium chloride cotransporter-2 (KCC2). It holds potential for applications in studies related to neurological disorders.
Formule :C₁₅H₁₇N₃OS
Couleur et forme :Solid
Masse moléculaire :287.38
Ref: TM-T203414
+ Info
Carbonic anhydrase inhibitor 32
Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.
Formule :C₁₇H₁₆N₆O₃S
Couleur et forme :Solid
Masse moléculaire :384.41
Ref: TM-T207684
+ Info
α-Casozepine
CAS :
- 117592-45-7
α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.
Formule :C₆₀H₉₄N₁₄O₁₆
Couleur et forme :Solid
Masse moléculaire :1267.47
Ref: TM-T29892
+ Info
Ruzinurad
CAS :
- 1638327-48-6
Ruzinurad (WO2020088641, compound I) is a potent URAT1 inhibitor, exhibiting high selectivity.
Formule :C₁₄H₁₂BrNO₂S
Couleur et forme :Solid
Masse moléculaire :338.22
Ref: TM-T39116
+ Info
AR-C141990 hydrochloride
CAS :
- 2250019-94-2
AR-C141990 HCl inhibits MCT-1 (pKi 7.6) and MCT-2 (pKi 6.6), and has immunosuppressive effects.
Formule :C₂₆H₂₉ClN₄O₄S
Couleur et forme :Solid
Masse moléculaire :529.05
Ref: TM-T39767
+ Info
Venturicidin A
CAS :
- 33538-71-5
Venturicidin A is a macrolide antibiotic.
Formule :C₄₁H₆₇NO₁₁
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :749.97
Ref: TM-T23505
+ Info
P-gp/BCRP-IN-2
P-gp/BCRP-IN-2 (compound 15), an oxadiazole derivative, functions as a dual inhibitor targeting both the ABC transporter P-glycoprotein (IC50: 1.6 nM) and BCRP
Formule :C₃₂H₃₅N₃O₆
Couleur et forme :Solid
Masse moléculaire :557.64
Ref: TM-T79353
+ Info
Chlorpropylate
CAS :
- 5836-10-2
Chlorpropylate is an insecticide.
Formule :C₁₇H₁₆Cl₂O₃
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :339.21
Ref: TM-T27010
+ Info
URAT1 inhibitor 11
CAS :
- 2416416-13-0
URAT1 inhibitor11 (Compound 7) is a potent URAT1 inhibitor, exhibiting an IC50 of 0.18 μM. It effectively reduces uric acid levels in zebrafish with hyperuricemia induced by Potassium oxonate and Xanthinesodium salt.
Formule :C₂₀H₁₆F₄N₂O₂
Couleur et forme :Solid
Masse moléculaire :392.35
Ref: TM-T203142
+ Info
Camegliptin
CAS :
- 813452-18-5
Cameglipti, a dipeptidyl peptidase IV (DPP-4) inhibitor, is used potentially for the treatment of type 2 diabetes.
Formule :C₂₀H₂₈FN₃O₃
Couleur et forme :Solid
Masse moléculaire :377.45
Ref: TM-T26941
+ Info
FD 12-9
CAS :
- 1451741-22-2
FD 12-9, Anti-glioblastoma activity. is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively.
Formule :C₅₁H₄₇N₃O₁₁
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :877.93
Ref: TM-T11268
+ Info
Aglafoline
CAS :
- 143901-35-3
Aglafoline inhibits in a concentration-dependent manner the aggregation and ATP release reaction induced in washed rabbit platelets by PAF (platelet-activating
Formule :C₂₈H₂₈O₈
Couleur et forme :Solid
Masse moléculaire :492.52
Ref: TM-T10260
+ Info
TRPA1 Antagonist 3
CAS :
- 71291-80-0
TRPA1 Antagonist 3 is a compound with photoswitchable properties that acts as an agonist on the TRPA1 channel, providing the ability for optical control.
Formule :C₁₁H₈ClN₃
Couleur et forme :Solid
Masse moléculaire :217.66
Ref: TM-T40822
+ Info
Cyclocreatine
CAS :
- 35404-50-3
Cyclocreatine, a creatine analogue and substrate for creatine kinase, inhibits creatine metabolism and prostate cancer cell proliferation.
Formule :C₅H₉N₃O₂
Degré de pureté :99.864%
Couleur et forme :Solid
Masse moléculaire :143.14
Ref: TM-T40445
+ Info
4-Hydroxytolbutamide
CAS :
- 5719-85-7
4-Hydroxytolbutamide is a drug metabolite derived from the metabolism of Tolbutamide by CYP2C8 and CYP2C9 a sulfonylurea hypoglycemic agent.
Formule :C₁₂H₁₈N₂O₄S
Degré de pureté :98%
Couleur et forme :White To Off-White
Masse moléculaire :286.35
Ref: TM-T14040
+ Info
Bafilomycin B1
CAS :
- 88899-56-3
Bafilomycin B1, a Streptomyces-derived macrolide, inhibits E. coli ATPase and fights Gram-positive bacteria and fungi.
Formule :C₄₄H₆₅NO₁₃
Degré de pureté :98%
Couleur et forme :White Powder
Masse moléculaire :815.998
Ref: TM-T10455
+ Info
Antimalarial agent 41
Antimalarial agent 41 (Compound 17) exhibits antimalarial activity by inhibiting the malaria parasite Plasmodium falciparum, with IC50 values of 40 nM for NF54 strain and 76 nM for K1 strain. This compound acts as an inhibitor of P. falciparum phosphatidylinositol-4-kinase β (PfPI4K) and hERG channels, with IC50 values of 53 nM and 3 μM, respectively. Additionally, Antimalarial agent 41 shows cytotoxicity against CHO cells, with an IC50 of 34 μM. It can improve malaria infections and demonstrates favorable pharmacokinetic properties in mouse models.
Formule :C₁₉H₁₈F₃N₅
Masse moléculaire :373.15143
Ref: TM-T210205
+ Info
UK-59811 hydrochloride
CAS :
- 2250025-89-7
UK-59811 hydrochloride, Br-dihydropyridine derivative, blocks Ca V Ab channels in bacteria, IC50: 194 nM.
Formule :C₂₂H₃₀BrClN₂O₅
Couleur et forme :Solid
Masse moléculaire :517.85
Ref: TM-T39770
+ Info
Conantokin-T
CAS :
- 127476-26-0
Non-competitive NMDA receptor antagonist
Formule :C₁₁₀H₁₇₅N₃₁O₄₅S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :2683.81
Ref: TM-TP2235
+ Info
Homocarnosine
CAS :
- 3650-73-5
Homocarnosine is an endogenous dipeptide in cerebral regions and cerebrospinal fluid.
Formule :C₁₀H₁₆N₄O₃
Couleur et forme :Solid
Masse moléculaire :240.26
Ref: TM-T32098
+ Info
APETx2 TFA
APETx2 TFA from sea anemone is a selective ASIC3 inhibitor with a 63 nM IC50, reversing acid and inflammatory pain.
Formule :C₁₉₈H₂₈₁F₃N₅₄O₆₂S₆
Couleur et forme :Solid
Masse moléculaire :4675.02
Ref: TM-T75924
+ Info
CALP3
CAS :
- 261969-05-5
Cell-permeable CaM agonist, binds EF-hand, activates phosphodiesterase without Ca2+, inhibits Ca2+ toxicity, IC50=33μM.
Formule :C₄₄H₆₈N₁₀O₉
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :881.08
Ref: TM-TP1911
+ Info
(S)-PF-03716556
CAS :
- 928774-44-1
(S)-PF-03716556 can be used as an acid pump inhibitor for the treatment of disease conditions mediated by acid pump inhibitory activity.
Formule :C₂₂H₂₆N₄O₃
Degré de pureté :99.8% - 99.91%
Couleur et forme :Soild
Masse moléculaire :394.47
Ref: TM-T2093L
+ Info
ω-Conotoxin MVIIC
CAS :
- 147794-23-8
Peptide neurotoxin; wide spectrum blocker of N, P and Q type calcium channels.
Formule :C₁₀₆H₁₇₈N₄₀O₃₂S₇
Degré de pureté :98%
Couleur et forme :White Lyophilised Solid
Masse moléculaire :2749
Ref: TM-TP2064
+ Info
ω-Conotoxin MVIIC TFA
ω-Conotoxin MVIIC TFA is a peptide and neurotoxin blocks P-type and q-type voltage-sensitive neuronal Ca ++ channels (VGCCs) radiolabel immunoprecipitation.
Formule :C₁₀₆H₁₇₈N₄₀O₃₂S₇·C₂HF₃O₂
Couleur et forme :Solid
Masse moléculaire :2863.27
Ref: TM-T75726
+ Info
Detajmium bitartrate
CAS :
- 33774-52-6
Detajmium bitartrate is used as an antiarrhythmic drug.
Formule :C₃₁H₄₇N₃O₉
Couleur et forme :Solid
Masse moléculaire :605.72
Ref: TM-T25312L
+ Info
Isotachysterol 3
CAS :
- 22350-43-2
Isotachysterol 3 boosts calcium transport in gut and bone mobilization in kidneyless rats.
Formule :C₂₇H₄₄O
Couleur et forme :Solid
Masse moléculaire :384.64
Ref: TM-T37312
+ Info
Guangxitoxin 1E
CAS :
- 1233152-82-3
Guangxitoxin 1E acts as a gating modifier since it shifts the voltage-dependence of Kv2.1 K+ currents towards depolarized potentials.
Formule :C₁₇₈H₂₄₈N₄₄O₄₅S₇
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :3948.61
Ref: TM-TP1531
+ Info
AP14145 hydrochloride
CAS :
- 2387505-59-9
AP14145 hydrochloride inhibits KCa2.2 and KCa2.3 channels with 1.1 μM IC50, affecting AERP and antiarrhythmic in AF models.
Formule :C₁₈H₁₈ClF₃N₄O
Couleur et forme :Solid
Masse moléculaire :398.81
Ref: TM-T39963
+ Info
6-FAM-AEEAC-SHK TFA
6-FAM-AEEAC-SHK TFA, a peptide neurotoxin derived from Stichodactyla helianthus and conjugated with a fluorescent marker, selectively blocks voltage-gated potassium channels (kv1.1 and kv1.2). By prolonging action potentials, it interferes with neural signal conduction, making it valuable in neuroscience research.
Formule :C₁₉₆H₂₉₅N₅₅O₅₇S₇·xCHF₃O₂
Couleur et forme :Solid
Masse moléculaire :4558.23 (free acid)
Ref: TM-TP2872
+ Info
17(S)-HETE
CAS :
- 183509-25-3
Arachidonic acid and its CYP450 metabolite, 17(S)-HETE, regulate kidney electrolytes; 17(S)-HETE reduces proximal tubule ATPase activity by 70% at 2 μM.
Formule :C₂₀H₃₂O₃
Couleur et forme :Solid
Masse moléculaire :320.473
Ref: TM-T35849
+ Info
NSC799462
NSC799462, a triazole inhibitor, specifically targets p97 ATPase, exerting its effect by binding to a designated site on the p97 enzyme. This interaction induces localized structural alterations in p97, effectively inhibiting its ATPase activity with an IC 50 value of 15 nM.
Formule :C₃₀H₃₂F₂N₆O₃S
Couleur et forme :Solid
Masse moléculaire :594.68
Ref: TM-T200146
+ Info
Huwentoxin I
CAS :
- 769973-37-7
Huwentoxin I (HWTX-I) is a peptide toxin that targets and inhibits both voltage-gated sodium channels and N-type calcium channels.
Formule :C₁₆₁H₂₄₆N₄₈O₄₄S₆
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :3750.36
Ref: TM-T80185
+ Info
Trans (2,3)-Dihydrotetrabenazine
CAS :
- 171598-74-6
Trans (2,3)-Dihydrotetrabenazine is a Tetrabenazine metabolite, shows inhibition activity on vesicular monoamine transporter (VMAT2).
Formule :C₁₉H₂₉NO₃
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :319.44
Ref: TM-T12190
+ Info
TP-050
CAS :
- 3085030-47-0
TP-050: potent, selective NMDAR agonist, EC50 0.51 µM (GluN2A), 9.6 µM (GluN2D), BBB permeable, boosts hippocampal LTP.
Formule :C₁₆H₁₅ClF₂N₆O
Couleur et forme :Solid
Masse moléculaire :380.78
Ref: TM-T73491
+ Info
(R)-AMPA
CAS :
- 83654-13-1
inactive enantiomer of AMPA
Formule :C₇H₁₀N₂O₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :186.17
Ref: TM-T23220
+ Info
BeKm-1
CAS :
- 524962-01-4
Potent, selective hERG (KV11.1) blocker; doesn't affect 14 other K+ channels; extends QTc in rabbit heart dose-dependently.
Formule :C₁₇₄H₂₆₁N₅₁O₅₂S₆
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :4091.65
Ref: TM-TP2072
+ Info
N-hydroxy Riluzole
CAS :
- 179070-90-7
N-hydroxy Riluzole, a metabolite of riluzole, is mainly produced by CYP1A2 in human liver.
Formule :C₈H₅F₃N₂O₂S
Couleur et forme :Solid
Masse moléculaire :250.20
Ref: TM-T35919
+ Info
NF110
CAS :
- 111150-22-2
P2X3 antagonist
Formule :C₄₁H₃₂N₆NaO₁₇S₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :1031.97
Ref: TM-TP2273
+ Info
Sulcardine 2HCl
CAS :
- 343935-48-8
Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.
Formule :C₂₄H₃₅Cl₂N₃O₄S
Degré de pureté :99.33% - 99.76%
Couleur et forme :Soild
Masse moléculaire :532.523
Ref: TM-T83979
+ Info
Cavα2δ-IN-1
CAS :
- 2416957-09-8
Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a Ki
Formule :C₁₈H₂₇N₅O
Couleur et forme :Solid
Masse moléculaire :329.448
Ref: TM-T40071
+ Info
Cevadine
Cevadine is a natural product that can be used as a reference standard.
Formule :C₃₂H₄₉NO₉
Couleur et forme :Solid
Masse moléculaire :591.742
Ref: TM-T124525
+ Info
EVT-401
EVT-401 (P2X7 receptor antagonist-1), a purinergic P2X7 receptor antagonist, demonstrates efficacy in combating neuroinflammation [1].
Formule :C₂₂H₂₀F₄N₂O₃
Couleur et forme :Solid
Masse moléculaire :436.4
Ref: TM-T74409
+ Info
ω-Conotoxin GVIA
CAS :
- 106375-28-4
Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces (RS)-3,5-DHPG -induced long term depression in vivo.
Formule :C₁₂₀H₁₈₂N₃₈O₄₃S₆
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :3037
Ref: TM-TP2062
+ Info
A-317567
CAS :
- 371217-32-2
A-317567 is a potent acid-sensing ion channel 3 (ASIC-3) inhibitor with an IC50 of 1.025 μM, and it has antidepressant and antinociception effects[1][2].
Formule :C₂₇H₃₁N₃
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :397.56
Ref: TM-T14070
+ Info
Caloxin 2A1 acetate
Caloxin 2A1 acetate is an inhibitor of extracellular plasma membrane Ca2+-ATPase (PMCA) peptide.
Formule :C₆₆H₉₅N₁₉O₂₄
Degré de pureté :98.2%
Couleur et forme :Solid
Masse moléculaire :1538.57
Ref: TM-T40437L
+ Info
GsMTx4
CAS :
- 1209500-46-8
GsMTx-4, mechanosensitive and stretch-activated ion channel inhibitor (CAS 1209500-46-8).
Formule :C₁₈₅H₂₇₃N₄₉O₄₅S₆
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :4095.84
Ref: TM-TP1670
+ Info
Resolvin D2
CAS :
- 810668-37-2
Resolvin D2 (RvD2) is a TRPV1 inhibitor and pro-ablative mediator with anti-inflammatory, anti-infective and pro-ablative effects.
Formule :C₂₂H₃₂O₅
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :376.49
Ref: TM-T12707
+ Info
12,14-Dichlorodehydroabietic acid
CAS :
- 65281-77-8
12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.
Formule :C₂₀H₂₆Cl₂O₂
Couleur et forme :Solid
Masse moléculaire :369.33
Ref: TM-T40750
+ Info
Halazone
CAS :
- 80-13-7
Halazone (Pantocid) is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.
Formule :C₇H₅Cl₂NO₄S
Degré de pureté :98.64%
Couleur et forme :Physical Description Fine White Powder With An Odor Of Chlorine (Ntp 1992)
Masse moléculaire :270.09
Ref: TM-T0037
+ Info
CW2158
CW2158 (Compound 13) is a modulator of exportin1 (XPO1). It disrupts chromatin binding and inhibits the activation of NFAT transcription factors and T cells.
Formule :C₁₄H₈F₄N₄O₂
Masse moléculaire :340.05834
Ref: TM-T209678
+ Info
AmmTX3
KV4 channel blocker that inhibits A-type K+ current in mouse neurons; requires DPP6 and DPP10 for effect.
Formule :C₁₅₈H₂₆₂N₅₀O₄₈S₆
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :3822.47
Ref: TM-TP2090
+ Info
Eltanexor
CAS :
- 1642300-52-4
Eltanexor, an oral XPO1 inhibitor, induces apoptosis in leukemia cells; EC50=60.9 nM.
Formule :C₁₇H₁₀F₆N₆O
Degré de pureté :99.6% - ≥98%
Couleur et forme :Solid
Masse moléculaire :428.29
Ref: TM-T11766L
+ Info
Verruculogen
CAS :
- 12771-72-1
Verruculogen, a toxin from Penicillium/Aspergillus, blocks Ca2+-K+ channels and halts mammalian M phase.
Formule :C₂₇H₃₃N₃O₇
Degré de pureté :98%
Couleur et forme :White Powder
Masse moléculaire :511.57
Ref: TM-T13297
+ Info
SLC26A3-IN-2
CAS :
- 950348-60-4
Vilobelimab (CaCP-29) is a human-mouse chimeric IgG antibody targeting human complement component 5a, a C5a inhibitor that inhibits neutrophil activation.
Formule :C₁₉H₁₃ClN₂O₂S
Degré de pureté :99.86%
Couleur et forme :Solid
Masse moléculaire :368.84
Ref: TM-T74815
+ Info
Furosemide sodium
CAS :
- 41733-55-5
Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.
Formule :C₁₂H₁₀ClN₂NaO₅S
Degré de pureté :99.52% - >99.99%
Couleur et forme :Solid
Masse moléculaire :352.73
Ref: TM-T35336
+ Info
GS-9191 PM
GS-9191 PM: novel antitumorviral bis-amide prodrug, inhibits MDR1/BCRP, has antiproliferative activity.
Formule :C₁₁H₁₆N₆O
Degré de pureté :99.79%
Couleur et forme :Soild
Masse moléculaire :248.28
Ref: TM-T67821
+ Info
SNX-482
CAS :
- 203460-30-4
Potent CaV2.3 calcium channel blocker, selective, voltage-dependent, with 30 nM IC50. Offers antinociceptive effects on C and Aδ fibres.
Formule :C₁₉₂H₂₇₄N₅₂O₆₀S₇
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :4495.01
Ref: TM-TP2118
+ Info
Apamin
CAS :
- 24345-16-2
Apamin: 18-amino acid bee venom peptide, blocks SK channels, anti-inflammatory, anti-fibrotic, strongly basic.
Formule :C₇₉H₁₃₁N₃₁O₂₄S₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :2027.34
Ref: TM-TP1223
+ Info
TRPA1-IN-2
CAS :
- 2415206-22-1
TRPA1-IN-2 is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM.TRPA1-IN-2 has anti-inflammatory activity.
Formule :C₂₄H₂₅F₃N₄O
Degré de pureté :98.05%
Couleur et forme :Soild
Masse moléculaire :442.48
Ref: TM-T77511
+ Info
NSC156529
CAS :
- 41134-88-7
NSC156529 suppresses AKT1, reduces cancer cell growth in vitro, and inhibits prostate tumors in vivo.
Formule :C₂₈H₂₁ClS₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :457.05
Ref: TM-T28203
+ Info
(Rac)-Tezacaftor
CAS :
- 1226709-85-8
(Rac)-Tezacaftor, a racemate, corrects F508del CFTR for cystic fibrosis research.
Formule :C₂₆H₂₇F₃N₂O₆
Couleur et forme :Solid
Masse moléculaire :520.5
Ref: TM-T75230
+ Info
c-Met-IN-23
c-Met-IN-23 (Compound 12g) functions as a c-Met inhibitor with an IC50 of 0.052 μM against c-Met. It also inhibits the MDR1 and MRP1/2 pumps in cancerous HepG2 and BxPC3 cells. As such, c-Met-IN-23 serves as an anticancer agent.
Formule :C₁₆H₁₃N₇O
Masse moléculaire :319.11816
Ref: TM-T209390
+ Info
3-Aminopropylphosphinic acid
CAS :
- 103680-47-3
3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).
Formule :C₃H₁₀NO₂P
Couleur et forme :Solid
Masse moléculaire :123.092
Ref: TM-T38438
+ Info
Analgesic/antidepressant agent-1
Analgesic/antidepressant agent-1 (Compound k1) is an orally active N-acetylamino chloro ketone derivative capable of crossing the blood-brain barrier. It exhibits high affinity for NMDA receptors and demonstrates analgesic, anti-inflammatory, and antidepressant properties, with low psychotomimetic activity.
Formule :C₂₂H₂₅ClN₂O₂
Couleur et forme :Solid
Masse moléculaire :384.9
Ref: TM-T205604
+ Info
NF864
CAS :
- 69606-09-3
NF864, a suramin analog, is a P2X1 receptor inhibitor.
Formule :C₅₇H₂₈N₆Na₁₂O₄₁S₁₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :2113.5
Ref: TM-T25863
+ Info
ProTx II
CAS :
- 484598-36-9
Selective NaV1.7 inhibitor, alters activation, reduces current, 100x more selective for 1.7 over other Na+ channels.
Formule :C₁₆₈H₂₅₀N₄₆O₄₁S₈
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :3826.59
Ref: TM-TP1680
+ Info
Astressin 2B
CAS :
- 681260-70-8
CRF2 antagonist with IC50 of 1.3 nM; >500 nM for CRF1. Aids gastric emptying.
Formule :C₁₈₃H₃₀₇N₄₉O₅₃
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :4041.69
Ref: TM-TP2095
+ Info
Dihydroisopimaric acid
CAS :
- 5673-36-9
Dihydroisopimaric acid opens BKαβ1 channels - large Ca²⁺-activated K⁺ conductors, verified by whole-cell voltage clamp.
Formule :C₂₀H₃₂O₂
Couleur et forme :Solid
Masse moléculaire :304.47
Ref: TM-T40650
+ Info
Vedroprevir
CAS :
- 1098189-15-1
Vedroprevir (GS9451), a selective HCV NS3 protease inhibitor, targets genotype 1 HCV.
Formule :C₄₅H₆₀ClN₇O₉S
Couleur et forme :Solid
Masse moléculaire :910.53
Ref: TM-T35043
+ Info
AQP4 (201-220)
CAS :
- 2104700-59-4
AQP4 (201-220) is the encephalitogenic epitope of AQP-4. AQP4 (201-220) can induce experimental autoimmune encephalomyelitis (EAE), characterized by midline brain lesions, retinal lesions, and lesions at the gray matter/white matter boundary of the spinal cord. AQP-4 is the target antigen in neuromyelitis optica.
Formule :C₉₇H₁₄₃N₂₇O₂₇S
Couleur et forme :Solid
Masse moléculaire :2151.4
Ref: TM-TP3213
+ Info
rac-trans-4-hydroxy Glyburide
CAS :
- 23155-00-2
rac-trans-4-hydroxy Glyburide, a metabolite of glyburide, inhibits binding at SUR1/Kir6.2 sites with IC50 values of 0.95 and 100 nM.
Formule :C₂₃H₂₈ClN₃O₆S
Couleur et forme :Solid
Masse moléculaire :510.0
Ref: TM-T35635
+ Info
N-Arachidonoyl Taurine
CAS :
- 119959-65-8
N-Arachidonoyl taurine, an amino acid, activates TRPV1/TRPV4, is metabolized by lipoxygenase, and affects insulin secretion and calcium flux.
Formule :C₂₂H₃₇NO₄S
Couleur et forme :Solid
Masse moléculaire :411.6
Ref: TM-T35918
+ Info
JAMI1001A
CAS :
- 1001019-46-0
JAMI1001A enhances AMPA receptor signaling, slows deactivation/desensitization for flip/flop isoforms.
Formule :C₁₆H₁₇F₃N₄O₃S
Couleur et forme :Solid
Masse moléculaire :402.39
Ref: TM-T38392
+ Info
P2X4 antagonist-3
P2X4 antagonist-3 (Compound 14c) is a P2X4 inhibitor with an IC50 value of 1.2 μM. It holds potential for research into neuroinflammation, chronic pain, and cancer progression.
Formule :C₁₉H₂₀FN₃O₄
Couleur et forme :Solid
Masse moléculaire :373.38
Ref: TM-T205694
+ Info
AHN-683
CAS :
- 143934-15-0
AHN-683 is a fluorescent ligand. It was used for peripheral-type benzodiazepine receptors.
Formule :C₄₂H₃₂FN₃O₇
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :709.72
Ref: TM-T23675
+ Info
PDDHV
CAS :
- 179469-40-0
PDDHV: a capsaicin-like vanilloid selective for rat TRPV1; induces Ca2+ uptake in neurons, EC50 of 70 nM.
Formule :C₄₉H₇₂O₁₁
Couleur et forme :Solid
Masse moléculaire :837.09
Ref: TM-T37086
+ Info
Hyp9
CAS :
- 3118-34-1
Hyp9, a specific agonist for the transient receptor potential canonical 6 (TRPC6) channel, is utilized in spinal cord injury (SCI) research [1].
Formule :C₁₈H₂₆O₅
Couleur et forme :Solid
Masse moléculaire :322.40
Ref: TM-T75550
+ Info
Atagabalin
CAS :
- 223445-75-8
Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.
Formule :C₁₀H₁₉NO₂
Couleur et forme :Solid
Masse moléculaire :185.26
Ref: TM-T30188
+ Info
Mambalgin 1
CAS :
- 1609937-15-6
ASIC1a inhibitor; IC50: 192 nM (human), 72 nM (dimer); inactive channel binding; selective; pain response delay.
Formule :C₂₇₂H₄₂₉N₈₅O₈₄S₁₀
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :6554.51
Ref: TM-TP2003
+ Info
Cyclic ADP-ribose ammonium
cADPR ammonium is a second messenger that boosts cytosolic calcium via Ryanodine receptors and TRPM2 channels.
Couleur et forme :Liquid
Ref: TM-T37687
+ Info
Chlorotoxin
CAS :
- 163515-35-3
Chlorotoxin: 36-amino acid peptide from deathstalker scorpion venom; blocks small chloride channels.
Formule :C₁₅₈H₂₄₉N₅₃O₄₇S₁₁
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :3995.71
Ref: TM-TP1431
+ Info
NSC265473
CAS :
- 61786-74-1
NSC265473 is an ABCG2 substrate.
Formule :C₂₁H₃₅N₃O₄S
Couleur et forme :Solid
Masse moléculaire :425.58
Ref: TM-T33753
+ Info
Foslevcromakalim
CAS :
- 1802655-72-6
Foslevcromakalim (QLS-101), an ATP-sensitive potassium channel opener, serves as a proagent for ocular hypotensive effects [1] [2].
Formule :C₁₆H₁₉N₂O₆P
Couleur et forme :Solid
Masse moléculaire :366.31
Ref: TM-T75084
+ Info
Antidepressant agent 3
Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.
Formule :C₁₇H₃₀ClN₅O₂S
Couleur et forme :Solid
Masse moléculaire :403.97
Ref: TM-T75002
+ Info
(±)17-HETE
CAS :
- 128914-47-6
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.
Formule :C₂₀H₃₂O₃
Couleur et forme :Solid
Masse moléculaire :320.473
Ref: TM-T35523
+ Info
ProTx-I
CAS :
- 484598-35-8
Selective blocker for CaV3.1 (IC50 = 0.2 μM), CaV3.2 (31.8 μM), also inhibits NaV1.8 and blocks KV2.1 channels.
Formule :C₁₇₁H₂₄₅N₅₃O₄₇S₆
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :3987.51
Ref: TM-TP1968
+ Info
N-Oleoyl Glutamine
CAS :
- 247150-73-8
N-Oleoyl Glutamine (Oleoyl-L-glutamine) antagonizes TRPV1 of the transient receptor potential (TRP) calcium channel.
Formule :C₂₃H₄₂N₂O₄
Degré de pureté :99.61%
Couleur et forme :Solid
Masse moléculaire :410.59
Ref: TM-T36064
+ Info
5-Hydroxy-2′,3,4′,7-tetramethoxyflavone
CAS :
- 19056-75-8
5-Hydroxy-2′,3,4′,7-tetramethoxyflavone shows weak ABCG2 inhibitory potency with IC50s of 3.27 and 3.89 µM in the Hoechst 33342 and pheophorbide A assays.
Formule :C₁₉H₁₈O₇
Degré de pureté :98%
Couleur et forme :Soild
Masse moléculaire :358.34
Ref: TM-TN7124
+ Info
RuBi-GABA
CAS :
- 1028141-88-9
Ruthenium-bipyridine-triphenylphosphine caged GABA
Formule :C₄₂H₃₉F₆N₅O₂P₂Ru
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :922.8
Ref: TM-T23277
+ Info
Kurtoxin
Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor, exhibiting a dissociation constant (Kd) of 15 nM for the Cav3.1 (α1G T-type)
Formule :C₃₂₄H₄₇₈N₉₄O₉₀S₈
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :7386.36
Ref: TM-T80496
+ Info
HG1 Toxin
HG1 Toxin is a peptide found in the venom of the scorpion Heterometrus fulvipes, known for its ability to inhibit the potassium channel Kv1.3 (potassium channel Kv1.3). Additionally, HG1 Toxin exhibits trypsin inhibitory activity (Ki=107 nM), making it useful for research into autoimmune diseases.
Formule :C₃₃₇H₅₀₃N₁₀₃O₉₇S₆
Masse moléculaire :7736.59176
Ref: TM-TP3643
+ Info
GSK2332255B
CAS :
- 1366233-41-1
GSK2332255B: potent TRPC3/6 antagonist; IC50 5 nM (TRPC3), 4 nM (TRPC6); over 100-fold selectivity vs other Ca2+ channels.
Formule :C₁₈H₁₉ClFN₃O₃S
Couleur et forme :Solid
Masse moléculaire :411.88
Ref: TM-T38780
+ Info
L-Palmitoylcarnitine TFA
L-Palmitoylcarnitine TFA: long-chain fat metabolite that disrupts membranes in ischaemia & inhibits KATP channels via Kir6.2 interaction.
Formule :C₂₅H₄₆F₃NO₆
Couleur et forme :Solid
Masse moléculaire :513.63
Ref: TM-T73764
+ Info
Levamlodipine besylate Hemipentahydrate
CAS :
- 884648-62-8
Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.
Formule :C₂₀H₂₅ClN₂O₅·C₆H₆O₃SH₂O
Couleur et forme :Solid
Masse moléculaire :1224.18
Ref: TM-T204904
+ Info
Ziconotide
CAS :
- 107452-89-1
Ziconotide: analgesic from cone snail for severe, chronic pain; synthetic ω-conotoxin.
Formule :C₁₀₂H₁₇₂N₃₆O₃₂S₇
Degré de pureté :98%
Couleur et forme :White Powder
Masse moléculaire :2639.13
Ref: TM-TP1559
+ Info
SC 4453
CAS :
- 59712-21-9
SC 4453 is a digoxin analog and a cardiac glycoside derivative.
Formule :C₄₁H₆₄N₂O₁₂
Couleur et forme :Solid
Masse moléculaire :776.965
Ref: TM-T34554
+ Info
APETx2
CAS :
- 713544-47-9
ASIC3 inhibitor; IC50: 63 nM (rat), 175 nM (human). Blocks NaV1.8, NaV1.2; analgesic for acid/inflammatory pain.
Formule :C₁₉₆H₂₈₀N₅₄O₆₁S₆
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :4561.06
Ref: TM-TP2081
+ Info
Nav1.7-IN-8
CAS :
- 1432913-44-4
Nav1.7-IN-8 selectively inhibits NaV1.7 over hNaV1.1/1.5, affects CYP2C9/3A4 (IC50: 0.17/0.077 μM), and provides rodent pain relief.
Formule :C₂₁H₁₂ClF₂N₅O₄S₂
Couleur et forme :Solid
Masse moléculaire :535.93
Ref: TM-T38911
+ Info
Ebio3
Ebio3 is a selective potassium ion channel (KCNQ2) inhibitor with an IC50 of 1.2 nM. It binds to the KCNQ2 channel via its hydrophobic tail, causing the inward movement of the S6 helix, which results in the closure of the internal gate. The inhibitory effect of Ebio3 is equally effective on pathogenic KCNQ2 mutants, such as R75C and I238L, reducing their outward current by approximately 80%. Ebio3 holds potential for research in neurological disorders like epilepsy.
Formule :C₁₉H₂₃F₂N₃O₂
Couleur et forme :Solid
Masse moléculaire :363.4
Ref: TM-T205242
+ Info
ATP Synthesis-IN-2
ATP Synthesis-IN-2 (Compound 5) serves as a potent inhibitor of ATP synthesis activity, displaying significant antibacterial properties with an IC50 value of 0.
Couleur et forme :Odour Solid
Ref: TM-T82944
+ Info
Anticonvulsant agent 9
Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.
Formule :C₂₂H₂₄N₄O₂
Couleur et forme :Solid
Masse moléculaire :376.45
Ref: TM-T205256
+ Info
Crofelemer
CAS :
- 148465-45-6
Crofelemer (Provir) is an orally active antidiarrheal agent. It targets the cystic fibrosis transmembrane conductance regulator (CFTR) and calcium-activated chloride channels (CACC), which are responsible for chloride and fluid secretion in the gastrointestinal tract. Crofelemer is applicable for research in diarrhea-related conditions.
Couleur et forme :Solid
Ref: TM-T205474