Protéases/Protéasome
Les inhibiteurs de protéases et de protéasomes sont des composés qui bloquent l'activité des protéases et du protéasome, impliqués dans la dégradation et le renouvellement des protéines. Ces inhibiteurs sont essentiels pour étudier la régulation de l'homéostasie des protéines, le contrôle du cycle cellulaire et l'apoptose. Les inhibiteurs de protéases et de protéasomes sont également utilisés dans le traitement de maladies telles que le cancer, où une dégradation anormale des protéines joue un rôle dans la progression de la maladie. En inhibant les protéases ou le protéasome, ces composés peuvent induire la mort cellulaire dans les cellules cancéreuses et sont des outils essentiels tant pour la recherche fondamentale que pour le développement thérapeutique. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de protéases et de protéasomes de haute qualité pour soutenir vos recherches en biochimie, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Protéases/Protéasome"
- Acétyl-CoA Carboxylase(38 produits)
- Cystéine protéase(111 produits)
- DPP-4(27 produits)
- Glutaminase(46 produits)
- Protéase du VIH(506 produits)
- PAI-1(26 produits)
- Inhibiteurs de protéase(50 produits)
- Récepteur activé par une protéase(55 produits)
- Protéasome(86 produits)
- Sérine protéase(54 produits)
- p97(15 produits)
Affichez 3 plus de sous-catégories
984 produits trouvés pour "Protéases/Protéasome"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
TR-107
CAS :TR-107 (Anticancer agent 230) is a mitochondrial protease ClpP activator that inhibits tumor growth in the MDA-MB-231 xenograft model.Formule :C22H19ClN4OCouleur et forme :SoildMasse moléculaire :390.87Platelet aggregation-IN-1
Platelet aggregation-IN-1 (Compound 10e) acts as an inhibitor of platelet aggregation and can achieve complete (100%) inhibition of thrombin-induced platelet aggregation at a concentration of 50 μM.Formule :C18H13N3O4Masse moléculaire :335.09061Fotagliptin benzoate
CAS :Fotagliptin benzoate, a DPP-4 inhibitor (IC50=2.27 nM), is safe in rats/dogs, useful for Type 2 diabetes research.Formule :C24H25FN6O3Couleur et forme :SolidMasse moléculaire :464.49TWH106
TWH106 is an inhibitor of the cyclophilin (Cyp) enzyme, exhibiting strong affinity for CypA and CypB with dissociation constants (KD) of 53 nM and 139 nM, respectively. It effectively inhibits the replication of HIV and HCV, demonstrating antiviral activity.Couleur et forme :Odour SolidMeOSuc-AAPA-CMK
MeOSuc-AAPA-CMK is a potent inhibitor of human neutrophil elastase (HNE) [1].Formule :C20H31ClN4O8Couleur et forme :SolidMasse moléculaire :490.94Bortezomib analog
Bortezomibanalog (Compound 13) is an analog of Bortezomib, functioning as an active control ligand for the 20S proteasome subunit β5.Couleur et forme :Odour SolidSitagliptin fenilalanil hydrochloride
CAS :Sitagliptin phenylalanine hydrochloride, a dipeptidyl peptidase-4 (DPP-4) inhibitor [1], is a chemical compound utilized in medical applications.Formule :C25H25ClF6N6O2Couleur et forme :SolidMasse moléculaire :590.95Hepcidin-1 (mouse)
CAS :Hepcidin-1 (mouse) is a peptide hormone that regulates iron balance, elevates mRNA for TRAP, cathepsin K, and MMP-9, and promotes TRAP-5b protein secretion.Formule :C111H169N31O35S8Couleur et forme :SolidMasse moléculaire :2754.24Tyrosinase-IN-36
Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.Couleur et forme :Odour SolidTiprelestat
CAS :Tiprelestat: strong inhibitor of human neutrophil elastase, anti-inflammatory, antimicrobial, used in inflammation/immune research.Formule :C254H416N72O75S10Couleur et forme :SolidMasse moléculaire :5999.09EP 171
CAS :EP 171 is a potent agonist of TP-receptors.Formule :C23H29FO5Couleur et forme :SolidMasse moléculaire :404.47Iso-VQA-ACC acetate
Iso-VQA-ACC acetate serves as a substrate for the constitutive proteasome.Couleur et forme :Odour SolidSTK33-IN-1
CAS :STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC 50 of 7 nM.Formule :C24H27N7O2Couleur et forme :SolidMasse moléculaire :445.527HCV-IN-7 hydrochloride
CAS :HCV-IN-7 hydrochloride: Oral, potent HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.Formule :C40H50Cl2N8O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :841.85Ichorcumab
CAS :Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.
Couleur et forme :LiquidRelacatib
CAS :Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.Formule :C27H32N4O6SCouleur et forme :SolidMasse moléculaire :540.64Stevia Powder
Stevia Powder, a natural sweetener, possesses antioxidant properties. It regulates antifibrotic pathways in cirrhotic rats, demonstrated by a reduction in hepatic stellate cells and decreased expression of matrix metalloproteinases MMP2 and MMP13. Furthermore, it increases the antifibrotic molecule Smad7, which helps prevent the elevation of serum necrosis and bile retention markers, thereby inhibiting the progression of liver fibrosis.Couleur et forme :Odour SolidHistatin 5 (TFA)(115966-68-2,free)
Histatin 5 (TFA)(115966-68-2,free) (Histatin 5 (TFA)) inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μMFormule :C135H196F3N51O35Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3150.32Sulodexide
CAS :Sulodexide is an orally administered combination of glycosaminoglycans, consisting of low molecular weight heparin (80%) and dermatan sulfate (20%). It demonstrates antithrombotic properties by interacting with antithrombin III (AT III) and heparin cofactor II (HC II), and by inhibiting thrombin formation. Additionally, sulodexide enhances profibrinolytic activity by releasing tissue plasminogen activator (tPA). It also offers endothelial protection, possesses anti-inflammatory effects, and alleviates chronic venous disease.Couleur et forme :SolidRadalbuvir
CAS :Radalbuvir (GS-9669) is an investigational antiviral agent for the treatment of hepatitis C virus (HCV) infection as an NS5B inhibitor.Formule :C30H41NO6SCouleur et forme :SolidMasse moléculaire :543.71Pseudostellarin G
CAS :Pseudostellarin G, a naturally occurring cyclo-octapeptide, exhibits inhibitory activity against tyrosinase and suppresses melanin production.Formule :C42H56N8O9Couleur et forme :SolidMasse moléculaire :816.94HCV-IN-4
CAS :HCV-IN-4: Potent, oral HCV NS5A inhibitor; effective vs GT1a/b, GT2b, GT3a, Y93H, L31V; EC90s: 3 pM-0.02 nM.Formule :C52H58FN9O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :956.07FiVe1
CAS :FiVe1 is a vimentin-binding compound that disrupts mitosis in cancer cells, causing cell death, with an IC50 of 234 nM in FOXC2-HMLER.Formule :C18H16Cl2N4Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :359.25Ref: TM-T9657
1mg86,00€5mg182,00€10mg274,00€25mg495,00€50mg745,00€100mg1.108,00€1mL*10mM (DMSO)À demanderEcallantide TFA
Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention ofCouleur et forme :Odour SolidRecombinant Proteinase K
Recombinant Proteinase K: serine protease, cleaves carboxy-terminus peptides, digests proteins, purifies nucleic acids.Couleur et forme :SolidCL 82198 hydrochloride
CAS :CL 82198 hydrochloride selectively inhibits MMP-13, not MMP-1/9/TACE, and blocks HP75 invasion and neurotoxicity in zebrafish.Formule :C17H23ClN2O3Couleur et forme :SolidMasse moléculaire :338.83CTTHWGFTLC, CYCLIC
CAS :CTT Gelatinase Inhibitor peptide blocks MMP-2/9, hindering cancer by stopping tumor growth.Formule :C52H71N13O14S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1166.33Lonodelestat TFA
Lonodelestat TFA, an oral peptide, selectively inhibits hNE, potentially aiding in CF research.Formule :C73H112F3N15O21Couleur et forme :SolidMasse moléculaire :1592.75MMP-9/MMP-13 Inhibitor I
CAS :MMP-9/MMP-13 Inhibitor I is a dual inhibitor of MMP-9 and MMP-13 with IC50 of both 0.9 nM.Formule :C25H25N3O6SCouleur et forme :SolidMasse moléculaire :495.55Rivulariapeptolides 1185
Rivulariapeptolides 1185 inhibits serine proteases; IC50: chymotrypsin 13.17 nM, elastase 23.59 nM, proteinase K 55.26 nM.Formule :C61H87N9O15Couleur et forme :SolidMasse moléculaire :1186.39Rivulariapeptolides 1155
Rivulariapeptolides 1155 inhibits chymotrypsin (41.84 nM), elastase (4.94 nM), and proteinase K (56.54 nM).Formule :C59H81N9O15Couleur et forme :SolidMasse moléculaire :1156.33LMP7/LMP2-IN-1
CAS :LMP7/LMP2-IN-1 (Compound 19) is an orally effective inhibitor targeting the immunoproteasome subunits LMP7 and LMP2, with respective IC50 values of 257 and 10 nM. This compound reduces the production of antibodies and downregulates the B cells in the germinal centers of the spleen and plasma cells in NP-OVA immunized mice. It has potential applications in the study of autoimmune diseases.Formule :C16H27BN4O3Couleur et forme :SoildMasse moléculaire :334.22Cathepsin L-IN-3
CAS :Cathepsin L-IN-3, a tripeptide-sized inhibitor of cathepsin L, effectively targets this specific enzyme.Formule :C41H49N7O4SCouleur et forme :SolidMasse moléculaire :735.94Recombinant Trypsin
Recombinant Trypsin is a serine protease that hydrolyzes proteins at the carboxyl side of lysine or arginine.(R)-BAY-85-8501
(R)-BAY-85-8501 is the less active enantiomer of BAY-85-8501. BAY-85-8501 is a selective and potent Human Neutrophil Elastase (HNE)inhibitor(IC50 of 65 pM).Formule :C22H17F3N4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :474.46Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS :Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effectFormule :C47H64N14O10Couleur et forme :SolidMasse moléculaire :985.1FFAGLDD
"FFAGLDD: MMP9 peptide for controlled DOX delivery inside cells."Formule :C37H49N7O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :783.82Z-Arg-Arg-βNA acetate
CAS :Z-Arg-Arg-βNA acetate serves as a sensitive dipeptide substrate for Cathepsin B protease, while demonstrating resistance to proteases H and L. This compound is crucial for differentiating non-Cathepsin B type proteins.Formule :C32H43N9O6Couleur et forme :SolidMasse moléculaire :649.74Acetyl-Calpastatin(184-210)(human) TFA
Acetyl-Calpastatin(184-210)(human) TFA inhibits μ-calpain (Ki 0.2 nM) and cathepsin L (Ki 6 μM) selectively and reversibly.Formule :C144H231F3N36O46SCouleur et forme :SolidMasse moléculaire :3291.65GSK2818713
CAS :GSK2818713 is a novel Hepatitis C NS5A replication complex inhibitor.Formule :C46H56N8O8Couleur et forme :SolidMasse moléculaire :849.002VPLSLYSG
CAS :VPLSLYSG, an octapeptide, degraded by MMP-9, MMP-1, MMP-2; potential MMP substrate uses.Formule :C39H62N8O12Couleur et forme :SolidMasse moléculaire :834.96VAMP
VAMP is a tetrapeptide that acts as a competitive dipeptidyl peptidase IV (DPP-IV) inhibitor, exhibiting an IC50 of 1.00 μM and a Kd of 6.89 μM. It effectively targets the DPP-IV-GLP-1 axis and is utilized in the research of type 2 diabetes.Formule :C18H32N4O5SCouleur et forme :SolidMasse moléculaire :416.535HCVP-IN-1
CAS :HCVP-IN-1 (compound 1) is a hepatitis C viral polymerase (HCVP) inhibitor.Formule :C30H34FN5O3Couleur et forme :SolidMasse moléculaire :531.632ZG36
ZG36, a human Caseinolytic protease P (ClpP) agonist, non-selectively degrades respiratory chain complexes and reduces mitochondrial DNA, causing mitochondrialCouleur et forme :Odour SolidCarboxypeptidase C
CAS :Carboxypeptidase C removes COOH-terminal amino acids and others in peptides for biochemical studies.Couleur et forme :SolidHistargin
CAS :Histargin is an enzyme inhibitor separated from Streptomyces roseoviridis.Formule :C14H25N7O4Couleur et forme :SolidMasse moléculaire :355.39Phaeosphaone D
CAS :Phaeosphaone D, a thiodiketopiperazine from Phaeosphaeria fuckelii fungus, inhibits mushroom tyrosinase (IC50 = 33.2 μM).Formule :C20H27N3O3S2Couleur et forme :SolidMasse moléculaire :421.58Rivulariapeptolides 988
Rivulariapeptolides 988 inhibits serine proteases: chymotrypsin (IC50 = 95.46 nM), elastase (15.29 nM), proteinase K (85.50 nM).Formule :C50H68N8O13Couleur et forme :SolidMasse moléculaire :989.12Dansyl-Glu-Gly-Arg-Chloromethylketone
CAS :Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor that specifically impedes serine/threonine proteases and has been shown to inhibit activatedFormule :C26H36ClN7O7SCouleur et forme :SolidMasse moléculaire :626.12Ala-Phe-Pro-pNA TFA
Ala-Phe-Pro-pNA TFA serves as a chromogenic substrate for tripeptidyl peptidase and can be utilized to assess the enzyme's activity.Couleur et forme :Odour SolidBMS-767778
CAS :BMS-767778, a DPP-4 inhibitor, is used potentially for the treatment of type 2 diabetes.Formule :C19H20Cl2N4O2Couleur et forme :SolidMasse moléculaire :407.29CRA-2059 TFA
CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].Couleur et forme :SolidZetomipzomib maleate
CAS :Zetomipzomib maleate (KZR-616) selectively targets LMP7/2 in immunoproteasomes, potential for autoimmune research.Formule :C34H46N4O12Couleur et forme :SolidMasse moléculaire :702.758Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2
CAS :Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic probe for MMP-1 and MMP-9 detection, releasing fluorescent Nma upon cleavage (Ex/Em: 340/440 nm).Formule :C49H68N14O12SCouleur et forme :SolidMasse moléculaire :1077.22Elastatinal
CAS :Elastatinal is an elastase inhibitor. It is found in culture filtrates of various species of actinomyces.Formule :C21H36N8O7Couleur et forme :Yellowish SolidMasse moléculaire :512.56NIM811
CAS :NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.Formule :C62H111N11O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1202.635AR-H067637
CAS :AR-H067637 is a fast-acting, reversible thrombin inhibitor with K(i) 2-4 nM; it also reduces clot-bound thrombin and platelet activation/aggregation.Formule :C21H21ClF2N4O4Couleur et forme :SolidMasse moléculaire :466.87Sofosbuvir impurity J
CAS :Sofosbuvir impurity J is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.Formule :C22H30FN4O8PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :528.47MK-6169
CAS :MK-6169 is an effective Pan-Genotype Hepatitis C Virus NS5A inhibitor. It also has Optimized Activity against Common Resistance-Associated Substitutions.Formule :C54H62FN9O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1016.25-epi-Arvestonate A
CAS :5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.
Formule :C16H26O5Couleur et forme :SolidMasse moléculaire :298.37CRA-2059 hydrochloride
CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].Couleur et forme :SolidChymotrypsinogen
CAS :Chymotrypsinogen is an inactive precursor of Chymotrypsin . Chymotrypsin is a serine protease produced by the pancreas [1] [2] .Couleur et forme :SolidPSI-7409
CAS :PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977).
Formule :C10H16FN2O14P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :500.16Leptosin D
CAS :Leptosin D, a thiodiketopiperazine alkaloid derived from mushrooms, effectively inhibits tyrosinase activity, demonstrating an inhibition concentration (IC50)Formule :C25H24N4O3S2Couleur et forme :SolidMasse moléculaire :492.61VD2173
CAS :VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.Formule :C31H45N9O6SCouleur et forme :SolidMasse moléculaire :671.81Enzyme-IN-1
CAS :Enzyme-IN-1（compound 1）为基于肽的N端亲核试剂（Ntn）水解酶抑制剂，特别针对20S蛋白酶体的糜胰蛋白酶样活性（CT-L）进行抑制，可能展现出抗炎特性。Formule :C36H50N4O7Couleur et forme :SolidMasse moléculaire :650.8DPP-4-IN-14
DPP-4-IN-14 (compound 30) is an inhibitor of DPP-4, with an IC50 value of 12.82 nM.Formule :C33H27N7O3Couleur et forme :SolidMasse moléculaire :569.613Tilpisertib fosmecarbil TFA
CAS :Tilpisertib fosmecarbil TFA, the TFA salt form of Tilpisertib, acts as an inhibitor of serine/threonine kinases. This compound also exhibits anti-inflammatory activity.Formule :C37H37ClF3N8O9PCouleur et forme :SolidMasse moléculaire :861.16DPP8/9-IN-1
DPP8/9-IN-1 (Compound 16) is a selective covalent inhibitor of dipeptidyl peptidase 8 and 9 (DPP8/9), with IC50 values of 14 nM and 298 nM, respectively. It irreversibly binds to the active site serine (such as S730 in DPP9) through a phosphate ester warhead, blocking substrate binding and inhibiting DPP8/9-mediated protein processing. DPP8/9-IN-1 holds potential for research in cancer and inflammatory diseases.Couleur et forme :Odour SolidN-CBZ-Phe-Arg-AMC
CAS :Z-FR-AMC substrate for serine proteases; cathepsins, kallikrein, plasmin. Substrate: 330/390 nm; Product: 342/441 nm.Formule :C33H36N6O6Degré de pureté :98%Couleur et forme :White To Off-White PowderMasse moléculaire :612.68SFTI-1
CAS :SFTI-1, a cyclic peptide trypsin inhibitor comprising 14 amino acid residues, is a potent Bowman-Birk inhibitor.Formule :C67H104N18O18S2Couleur et forme :SolidMasse moléculaire :1513.78L-Methionine-DL-sulfoximine
CAS :MSO blocks glutamine synthetase, impacts astroglia, and is used in convulsant research.Formule :C5H12N2O3SDegré de pureté :99.56% - ≥98%Couleur et forme :White Crystalline PowderMasse moléculaire :180.23Proteasome-IN-7
Proteasome-IN-7 (Compound 6f) is a macrolactam-based epoxyketone proteasome inhibitor with an IC50 value of 37.92 nM against the 20S proteasome ChT-L subunit. It exhibits potent antiproliferative effects on multiple myeloma, acute lymphoblastic leukemia, and non-small cell lung cancer.Formule :C48H56N6O10SCouleur et forme :SolidMasse moléculaire :909.06PF 00356231
CAS :PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).
Formule :C25H20N2O3SDegré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :428.5Neutrophil elastase inhibitor 4
Neutrophil elastase inhibitor 4 (compound 4f) is a competitive inhibitor of human neutrophil elastase (HNE) with IC50 of 42.30 nM and Ki of 8.04 nM.Formule :C20H21N3O5Couleur et forme :SolidMasse moléculaire :383.4Histatin 5
CAS :Histatin 5, a human saliva peptide, blocks MMP-2 and MMP-9 at IC50s of 0.57/0.25 μM and kills fungi.Formule :C133H195N51O33Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3036.29HIV-1 inhibitor-6
CAS :HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicingFormule :C14H10N4O4SDegré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :330.32Z-Leu-Tyr-Chloromethylketone
CAS :Z-Leu-Tyr-Chloromethylketone is a calpain inhibitor [1].Formule :C24H29ClN2O5Couleur et forme :SolidMasse moléculaire :460.95BPHA
CAS :BPHA is a selective oral inhibitor of MMP-2/9/14 (IC50: 12/16/17 nM), not affecting MMP-1/3/7, with anti-angiogenic and anti-tumor properties.Formule :C21H20N2O4SDegré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :396.46Ref: TM-T36712
1mg167,00€5mg442,00€10mg620,00€25mg954,00€50mg1.305,00€100mg1.738,00€200mg2.322,00€1mL*10mM (DMSO)442,00€Nitidanin
Nitidanin is a useful organic compound for research related to life sciences and the catalog number is T125599.Formule :C21H24O8Couleur et forme :SolidMasse moléculaire :404.415TMC647055 Choline salt
TMC647055 choline salt is a selective and cell-permeating inhibitor of HCV NS5B (IC50: 34 nM).Formule :C37H53N5O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :727.91Cathepsin C-IN-6
Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastaseFormule :C24H35N5O4·xC2HF3O2Couleur et forme :SolidLXE408 fumarate
LXE408 fumarate: orally available, selective kinetoplastid proteasome inhibitor with IC50/EC50 of 0.04 μM for L. donovani; potentially aids in VL research.
Formule :C27H22FN7O6Degré de pureté :99.89%Couleur et forme :SoildMasse moléculaire :559.51L 659286
CAS :L 659286 is one kind of cephalosporin derivative.Formule :C17H21N5O7S2Couleur et forme :SolidMasse moléculaire :471.51Nostosin G
Nostosin G, a linear peptide with Hpla, Hty, and argininal, inhibits trypsin effectively (IC50 = 0.1 μM).Formule :C25H33N5O6Couleur et forme :SolidMasse moléculaire :499.56Sadopeptins B
Sadopeptins B, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].Formule :C48H69N9O13SCouleur et forme :SolidMasse moléculaire :1012.18Talabostat
CAS :Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM.Formule :C9H19BN2O3Couleur et forme :SolidMasse moléculaire :214.07Ac-Phe-Gly-pNA
CAS :Ac-Phe-Gly-pNA is the chymotrypsin specific substrate [1] .Formule :C19H20N4O5Couleur et forme :SolidMasse moléculaire :384.39Aristololactam IIIa
CAS :Aristololactam IIIa inhibits superoxide and elastase generation; IC50: 0.12 μg/mL and 0.20 μg/mL.Formule :C16H9NO4Couleur et forme :SolidMasse moléculaire :279.25Sadopeptins A
Sadopeptins A, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].Formule :C49H71N9O13SCouleur et forme :SolidMasse moléculaire :1026.21RJS308
RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)Formule :C63H75N13O11SCouleur et forme :SolidMasse moléculaire :1222.42BAY 1217224
CAS :BAY 1217224 is a neutral, non-prodrug Thrombin inhibitor with good oral pharmacokinetics.
Formule :C24H27ClFN3O5Couleur et forme :SolidMasse moléculaire :491.94Monodes(N-carboxymethyl)valine Daclatasvir
CAS :Monodes(N-carboxymethyl)valine Daclatasvir, or Daclatasvir Impurity A, degrades Daclatasvir, a strong HCV NS5A inhibitor.Formule :C33H39N7O3Couleur et forme :SolidMasse moléculaire :581.71Calpain Inhibitor-1
CAS :Calpain Inhibitor-1, a potent Calpain 1 blocker, has IC50 of 100 nM and Ki of 2.89 μM.Formule :C19H17FN6O5SCouleur et forme :SolidMasse moléculaire :460.44Tyrosinase-IN-38
Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.Couleur et forme :Odour Solidmidesteine
CAS :Midesteine (MR-889) is a small molecule neutrophil elastase inhibitor used in the treatment of bronchitis, asthma and chronic lung disease.Formule :C12H13NO3S3Degré de pureté :99.87% - 99.98%Couleur et forme :SolidMasse moléculaire :315.43Anticancer agent 114
Anticancer agent 114: oral dipeptide boronic acid, proteasome inhibitor, IC 50 = 2.2 nM, halts RPMI-8226 cell growth, for multiple myeloma research.Formule :C28H33BF6N2O7Couleur et forme :SolidMasse moléculaire :634.37Berotralstat
CAS :Berotralstat (BCX7353) is an oral, low-toxicity, specific kallikrein inhibitor for hereditary angioedema research, blocking bradykinin release.Formule :C30H26F4N6OCouleur et forme :SolidMasse moléculaire :562.56Sofigatran
CAS :Sofigatran (MCC-977) is an oral anticoagulant targeting thrombin for cardiovascular research.Formule :C24H44N4O4SCouleur et forme :SolidMasse moléculaire :484.7TAPI1 acetate
TAPI1 acetate (TNF-α processing inhibitor-1) is a TACE (ADAM17) inhibitor that inhibits shedding of TNF-α cytokine receptors; MMP inhibitor .Formule :C28H41N5O7Degré de pureté :98.82% - 99.94%Couleur et forme :SolidMasse moléculaire :559.65
![Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT76347.webp&w=3840&q=75)
