Protéases/Protéasome
Les inhibiteurs de protéases et de protéasomes sont des composés qui bloquent l'activité des protéases et du protéasome, impliqués dans la dégradation et le renouvellement des protéines. Ces inhibiteurs sont essentiels pour étudier la régulation de l'homéostasie des protéines, le contrôle du cycle cellulaire et l'apoptose. Les inhibiteurs de protéases et de protéasomes sont également utilisés dans le traitement de maladies telles que le cancer, où une dégradation anormale des protéines joue un rôle dans la progression de la maladie. En inhibant les protéases ou le protéasome, ces composés peuvent induire la mort cellulaire dans les cellules cancéreuses et sont des outils essentiels tant pour la recherche fondamentale que pour le développement thérapeutique. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de protéases et de protéasomes de haute qualité pour soutenir vos recherches en biochimie, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Protéases/Protéasome"
- Acétyl-CoA Carboxylase(34 produits)
- Cystéine protéase(96 produits)
- DPP-4(20 produits)
- Glutaminase(40 produits)
- Protéase du VIH(447 produits)
- PAI-1(25 produits)
- Inhibiteurs de protéase(50 produits)
- Récepteur activé par une protéase(54 produits)
- Protéasome(94 produits)
- Sérine protéase(50 produits)
- p97(14 produits)
Affichez 3 plus de sous-catégories
1045 produits trouvés pour "Protéases/Protéasome"
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Lenacapavir
CAS :<p>Lenacapavir (GS-6207) is the first HIV-1 capsid inhibitor approved by the U.S. Food and Drug Administration, the European Medicines Agency, and Health Canada for the treatment of MDR HIV-1 infection.Cost-effective and quality-assured.</p>Formule :C39H32ClF10N7O5S2Degré de pureté :99.61% - 99.87%Couleur et forme :SolidMasse moléculaire :968.28Etarotene
CAS :<p>Etarotene (Arotinoid ethyl sulphone) is an ethylsulfonyl derivative of aloe acid with differentiation-inducing and potentially antitumor activity.Etarotene is a</p>Formule :C25H32O2SDegré de pureté :99.58% - 99.93%Couleur et forme :SolidMasse moléculaire :396.59BDCRB
<p>BDCRB disrupts HCMV DNA maturation by altering terminase cleavage, extending packaging 30 kb until second site.</p>Formule :C12H11BrCl2N2O4Degré de pureté :99.41% - 99.43%Couleur et forme :SoildMasse moléculaire :398.04BILB-1941
CAS :<p>BILB-1941 (BILB-1941ZW) is an inhibitor of HCV NS5B polymerase and can be used in studies about HCV infection.</p>Formule :C34H34N4O4Degré de pureté :99.51% - 99.65%Couleur et forme :SolidMasse moléculaire :562.662'-C-Methyladenosine
CAS :<p>2'-C-Methyladenosine from C. renalis inhibits HCV, NS5B RNA synthesis (IC50: 0.3, 1.9µM), and LRV1 in L. guyanensis, L. braziliensis.</p>Formule :C11H15N5O4Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :281.27CPA inhibitor
CAS :<p>CPA inhibitor (Carboxypeptidase inhibitor) is a potent carboxypeptidase A (CPA) inhibitor with a Ki of 0.32 μM.</p>Formule :C18H19NO4Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :313.35Cathepsin X-IN-1
CAS :<p>Cathepsin X-IN-1 (compound 25) reduces the migration of PC-3 cell with low cytotoxic that is a potent inhibitor of Cathepsin X (IC 50 = 7.13 μM) [1].</p>Formule :C15H13N3O3SDegré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :315.35P32/98 hemifumarate
CAS :<p>P32/98 hemifumarate is a DPP4 inhibitor with hypoglycemic properties and is used in the study of type 2 diabetes.</p>Formule :C22H40N4O6S2Degré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :520.71Atevirdine
CAS :<p>Atevirdine is an HIV-1 reverse transcriptase inhibitor with antiviral activity for the study of the AIDS dementia complex (ADC).</p>Formule :C21H25N5O2Degré de pureté :98.20%Couleur et forme :SolidMasse moléculaire :379.46DB04760
CAS :<p>DB04760: selective MMP-13 inhibitor, non-zinc-chelating, IC50=8nM, reduces paclitaxel neurotoxicity, anticancer.</p>Formule :C22H20F2N4O2Degré de pureté :99.93% - 99.99%Couleur et forme :SolidMasse moléculaire :410.42JNJ-10311795
CAS :<p>JNJ-10311795 (RWJ-355871) is an inhibitor of neutrophil elastase G and mast cell chymase, demonstrating significant anti-inflammatory effects.</p>Formule :C40H35N2O6PDegré de pureté :97.43%Couleur et forme :SolidMasse moléculaire :670.69TG-2-IN-1
CAS :<p>TG-2-IN-1 (Compound D003) is a transglutaminase-2 ( TGM-2 ) inhibitor. TG-2-IN-1 can be used in myopia research[1].</p>Formule :C8H13ClN2OSDegré de pureté :98.43%Couleur et forme :SolidMasse moléculaire :220.72CP-544439
CAS :<p>CP-544439 is an inhibitor of matrix metalloproteinase-13, which has an effect on adipose tissue development.</p>Formule :C18H19FN2O6SDegré de pureté :95.02% - 98.66%Couleur et forme :SolidMasse moléculaire :410.42Setrobuvir
CAS :<p>Setrobuvir (ANA-598) is an orally active non-nucleoside HCV NS5B polymerase inhibitor with inhibitory effects on de novo RNA synthesis and primer extension with</p>Formule :C25H25FN4O6S2Degré de pureté :98.92% - >99.99%Couleur et forme :SolidMasse moléculaire :560.62Granotapide
CAS :<p>Granotapide is a microsomal triglyceride transfer protein (MTP) inhibitor that treats and rather prevents atherosclerosis, coronary artery disease, metabolic</p>Formule :C39H37F3N2O8Degré de pureté :99.70% - 99.79%Couleur et forme :SolidMasse moléculaire :718.71PG-116800
CAS :<p>PG-116800 (PG-530742) is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.</p>Formule :C24H27N3O7SDegré de pureté :98.03% - 99.66%Couleur et forme :SolidMasse moléculaire :501.55Sovaprevir
CAS :<p>Sovaprevir is a non-structural 3 (NS3) protease inhibitor with antiviral activity for the treatment of HCV infection.</p>Formule :C43H53N5O8SDegré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :799.97Melagatran
CAS :<p>Melagatran is an orally available, direct synthetic thrombin inhibitor that does not require endogenous cofactors other than thrombin.Cost-effective and quality-assured.</p>Formule :C22H31N5O4Degré de pureté :98.29% - >99.99%Couleur et forme :SolidMasse moléculaire :429.51Opaviraline
CAS :<p>Opaviraline (GW-420867X) is a potent reverse transcriptase inhibitor that inhibits Human immunodeficiency virus 1 and has the potential to treat HIV infection.</p>Formule :C14H17FN2O3Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :280.29MMP2-IN-3
CAS :<p>MMP2-IN-3 is a potent inhibitor of matrix metalloproteinases (MMP-2) (IC50: 31 μM).</p>Formule :C23H21N3ODegré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :355.43Uprifosbuvir
CAS :<p>Uprifosbuvir is an inhibitor of uridine nucleotide analog HCV NS5B polymerase.</p>Formule :C22H29ClN3O9PDegré de pureté :99.73% - >99.99%Couleur et forme :SolidMasse moléculaire :545.91Sirpiglenastat
CAS :<p>Sirpiglenastat (DRP-104) is a glutamine antagonist, a prodrug of DON, with antitumor activity that acts by suppressing the adaptive immune system.</p>Formule :C22H27N5O5Degré de pureté :98.01% - 98.37%Couleur et forme :SolidMasse moléculaire :441.48Emivirine
CAS :<p>Emivirine (MKC-442) is a potent and selective nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1.</p>Formule :C17H22N2O3Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :302.37Tyrosinase-IN-2
CAS :<p>Tyrosinase-IN-2, a potent tyrosinase inhibitor, may help in skin lightening and food preservation research.</p>Formule :C8H8N4O2SDegré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :224.24Isatoribine
CAS :<p>Isatoribine(ANA245) free base is a potent TLR7 receptor agonist with anti-hepatitis C virus infection activity for the study of HCV infection.</p>Formule :C10H12N4O6SDegré de pureté :98.99% - 99.75%Couleur et forme :SolidMasse moléculaire :316.29AGPS-IN-2i
CAS :<p>AGPS-IN-2i inhibits alkylglycerol phosphate synthase, affecting ether lipid metabolism and reducing cancer cell migration and proliferation.</p>Formule :C18H17F2N3O2Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :345.34HIV-1 integrase inhibitor 8
CAS :<p>HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1].</p>Formule :C21H24O2Degré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :308.41TS-021
CAS :<p>TS-021 is a selective dipeptidyl peptidase 4 (DPP-4) inhibitor with antidiabetic activity for the study of type 2 diabetes.</p>Formule :C17H24FN3O5SDegré de pureté :>99.99% - >99.99%Couleur et forme :SolidMasse moléculaire :401.45MMP-2/MMP-9 Inhibitor I
CAS :<p>MMP-2/MMP-9-IN-1: oral IV collagenase inhibitor; IC50: 0.24 μM (MMP-9), 0.31 μM (MMP-2); targets cancer.</p>Formule :C21H19NO4SDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :381.44KM-023
CAS :<p>KM-023 is a new second-generation non-nucleoside reverse transcriptase inhibitor for the study of human immunodeficiency virus (HIV) type 1 infection.</p>Formule :C18H19N3O3Degré de pureté :99.47% - >99.99%Couleur et forme :SolidMasse moléculaire :325.36L 756423
CAS :<p>L756423 is a potent, selective HIV protease inhibitor (Ki=0.049 nM), effective against HIV spread in MT25 lymphocytes at 0.1-0.5 nM, useful for AIDS research.</p>Formule :C39H48N4O5Degré de pureté :99.34% - 99.88%Couleur et forme :SolidMasse moléculaire :652.8220S Proteasome activator 1
CAS :<p>20S Proteasome activator 1: IC50—0.3 μM (trypsin), 0.7 μM (chymotrypsin), 1.8 μM (caspase); reduces alpha-synuclein A53T, aids neurodegenerative studies.</p>Formule :C27H19ClF2N2OSDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :492.97Gemigliptin
CAS :<p>Gemigliptin (LC15-0444) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.)</p>Formule :C18H19F8N5O2Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :489.36MK-8325
CAS :<p>MK-8325 is a potent and orally available HCV NS5A inhibitor with replicative activity against a wide range of genotypes.MK-8325 has demonstrated bioavailability</p>Formule :C43H54Cl2F2N8O6SiDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :915.93Thrombin inhibitor 1
CAS :<p>Thrombin inhibitor 1 is a potent inhibitor of thrombin (Ki: 0.66 nM, 2xaPTT=0.43 μM).</p>Formule :C22H20Cl2F2N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :497.32GS-6620
CAS :<p>GS-6620 is a HCV nonstructural protein 5B (NS5B) inhibitor.</p>Formule :C29H37N6O9PCouleur et forme :SolidMasse moléculaire :644.61SSR 69071
CAS :<p>SSR69071: selective neutrophil elastase inhibitor, stronger for humans (Ki=0.0168 nM), may treat COPD, asthma, and reduce heart injury.</p>Formule :C27H32N4O7SCouleur et forme :SolidMasse moléculaire :556.63NS5A-IN-2
CAS :<p>NS5A-IN-2, a potent inhibitor, is highly effective against HCV 1b and shows increased activity for GT 3a with good metabolic stability.</p>Formule :C46H45N7O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :807.89XL-784
CAS :<p>XL-784 is a selective MMP inhibitor with low IC50s for MMP-1,2,3,8,9,13, modulating extracellular matrix remodeling, tumor invasion, and metastasis in cancer.</p>Formule :C42H42Cl2F4MgN6O16S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1122.15Ravidasvir HCl
CAS :<p>Ravidasvir, also known as PPI-668 and ASC16, is a second-generation, orally active, potent and selective HCV NS5A protein inhibitor.</p>Formule :C42H52Cl2N8O6Couleur et forme :SolidMasse moléculaire :835.828Inogatran
CAS :<p>Inogatran is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of venous and arterial thrombotic diseases.</p>Formule :C21H38N6O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.56Paltimatrectinib
CAS :<p>Paltimatrectinib (PBI-200) is a tyrosine kinase inhibitor with anticancer activity, and is used in the study of bladder, breast, and colorectal cancers.</p>Formule :C20H15F5N6Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :434.37ABP 25
CAS :<p>ABP 25 is a highly potent and selective activity-based probe (ABP) for cathepsin K imaging.</p>Formule :C55H66ClN5O3Couleur et forme :SolidMasse moléculaire :880.6Beclabuvir HCl
CAS :<p>Beclabuvir (BMS-791325) is an HCV inhibitor targeting NS5B polymerase with sub-28 nM potency for genotypes 1, 3, 4, 5.</p>Formule :C36H46ClN5O5SCouleur et forme :SolidMasse moléculaire :696.3BAY-678
CAS :<p>BAY-678: Oral selective human neutrophil elastase inhibitor; IC50: 20 nM; SGC-approved chemical probe.</p>Formule :C20H15F3N4O2Degré de pureté :97.89%Couleur et forme :SolidMasse moléculaire :400.35Proteasome-IN-5
CAS :<p>Proteasome-IN-5, also known as compound 5, acts as a proteasome inhibitor [1].</p>Formule :C20H30BN5O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :463.29Collagen proline hydroxylase inhibitor
CAS :<p>Collagen proline hydroxylase inhibitor is an inhibitor collagen proline hydroxylase and useful for antifibrotic proliferative agents.</p>Formule :C18H18N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :354.36Ro 31-9790
CAS :<p>Ro 31-9790 is a synthetic inhibitor of metalloproteinase (MMP).</p>Formule :C15H29N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :315.41ONO 4817
CAS :<p>ONO-4817 suppresses MMPs, limiting plaque progression and aortic hyperplasia in hyperlipidemic rabbits.</p>Formule :C22H28N2O6Couleur et forme :SolidMasse moléculaire :416.47MMP-7-IN-3
CAS :<p>MMP-7-IN-3 (compound 15) is a potent and selective MMP-7 inhibitor, inhibiting renal fibrosis in a unilateral ureteral obstruction mouse model.</p>Formule :C34H43ClF3N7O9SDegré de pureté :99.915%Couleur et forme :SolidMasse moléculaire :818.26KB-R7785
CAS :<p>KB-R7785 is a novel ADAM12/MMP inhibitor improving heart function and insulin sensitivity by blocking HB-EGF and TNF-alpha.</p>Formule :C18H27N3O4Couleur et forme :SolidMasse moléculaire :349.42Cipemastat
CAS :<p>Cipemastat is a competitive inhibitor of human collagenases 1, 2, and 3 (Kis: 3.0, 4.4, and 3.4 nM).</p>Formule :C22H36N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.55Azt-pmap
CAS :<p>AZT-PMPA, an aryl phosphate derivative of AZT and a nucleoside analogue, demonstrates anti-HIV activity[1].</p>Formule :C20H25N6O8PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :508.42XL-784 free base
CAS :<p>XL-784 free base selectively inhibits MMPs with IC50: MMP-1 (1.9µM), MMP-2 (0.81nM), MMP-3 (120nM), MMP-8 (10.8nM), MMP-9 (18nM), MMP-13 (0.56nM).</p>Formule :C21H22ClF2N3O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :549.93MDL 27324
CAS :<p>MDL 27324 is an inhibitor of human neutrophil elastase.</p>Formule :C29H38F3N5O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :641.7AA74-1
CAS :<p>AA74-1 is a potent, selective APEH inhibitor that significantly enhances T-cell proliferation by inhibiting APEH activity [1].</p>Formule :C16H28N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :308.42Ro 32-7315
CAS :<p>Ro 32-7315 is a selective inhibitor of ADAM17.</p>Formule :C22H35N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :453.6MK-3281
CAS :<p>MK-3281: Oral, potent HCV NS5B inhibitor with promising properties and efficacy in replication trials, suitable for clinical use.</p>Formule :C29H37N3O3Couleur et forme :SolidMasse moléculaire :475.62MDL 101146
CAS :<p>MDL 101146 is an orally active neutrophil elastase inhibitor.</p>Formule :C29H37F5N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :632.62JW 480
CAS :<p>JW480 is a potent and selective inhibitor of KIAA1363, a serine hydrolase enzyme.</p>Formule :C22H23NO2Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :333.42MMP-7-IN-2
CAS :<p>MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.</p>Formule :C28H40ClF3N6O9SDegré de pureté :97.82%Couleur et forme :SolidMasse moléculaire :729.17Proteasome β2c/i-IN-1
CAS :<p>Proteasome β2c/i-IN-1 (compound 37) serves as a selective inhibitor targeting the β2c and β2i subunits of the human proteasome [1].</p>Formule :C32H48N4O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :600.75ND-378
CAS :<p>ND-378 is a potent and selective inhibitor of MMP-2 with no inhibition on MMP-9 and MMP-14.</p>Formule :C18H19NO4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.48AZD-7295
CAS :<p>AZD-7295 (A-689) is an NS5A inhibitor that may be used to treat HCV infection.</p>Formule :C32H35F3N4O5SCouleur et forme :SolidMasse moléculaire :644.7PTC725
CAS :<p>PTC725 is a selective HCV 1b replicons inhibitor. It has been shown to target the nonstructural protein 4B.</p>Formule :C23H18F4N6O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :518.49EP1013
CAS :<p>EP1013 is a broad-spectrum selective inhibitor of Caspase used in the study of type 1 diabetes.</p>Formule :C18H23FN2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :382.38HIV-1 protease-IN-12
CAS :<p>HIV-1 protease-IN-12 (compound 35b) serves as a potent inhibitor of HIV-1 protease, exhibiting an IC50 value of 0.51 nM, and demonstrates efficacy against drug-</p>Formule :C25H35N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :489.63GSK-2485852
CAS :<p>GSK-2485852, a NS5B inhibitor, is used potentially for treatment of HCV infection.</p>Formule :C27H25BF2N2O6SCouleur et forme :SolidMasse moléculaire :554.37MMP13-IN-3
CAS :<p>MMP13-IN-3 is an oral, selective MMP-13 inhibitor with IC50 of 1 nM, >1000x selective, for osteoarthritis treatment.</p>Formule :C24H22N4O5Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :446.46TP0556351
CAS :<p>TP0556351: potent MMP2 inhibitor with 0.2 nM IC50, reduces collagen in pulmonary fibrosis mice.</p>Formule :C50H70N10O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1067.15Apratastat
CAS :<p>Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs)</p>Formule :C17H22N2O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :414.5MDL-101146, (R)-
CAS :<p>MDL-101146, (R)- is an effective orally active inhibitor of human neutrophil elastase.</p>Formule :C29H37F5N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :632.62LU-002i
CAS :<p>LU-002i is a selective inhibitor targeting the human proteasome subunits β2c and β2i, demonstrating an inhibitory concentration (IC50) of 220 nM for β2i [1].</p>Formule :C35H52N4O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :640.81Phe-Pro-Ala-pNA
CAS :<p>Phe-Pro-Ala-pNA is a chromogenic substrate utilized for assessing tripeptidyl peptidase activity.</p>Formule :C23H27N5O5Couleur et forme :SolidMasse moléculaire :453.49Flovagatran sodium
CAS :<p>Flovagatran sodium, a thrombin inhibitor, is used potentially for the treatment of thrombosis.</p>Formule :C27H36BN3NaO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :548.4Z-FG-NHO-BzOME
CAS :<p>Z-FG-NHO-BzOME is a chemical compound functioning as a cysteine protease inhibitor, selectively targeting and inhibiting cathepsin B, cathepsin L, cathepsin S,</p>Formule :C27H27N3O7Couleur et forme :SolidMasse moléculaire :505.52HIV-1 protease-IN-7
CAS :<p>HIV-1 protease-IN-7 (compound 16) is an orally active inhibitor of HIV-1 protease, exhibiting an IC50 of 3.52 nM and an EC50 of 37 nM [1].</p>Formule :C68H104N10O12SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1285.68BAY-320
CAS :<p>BAY-320 is a Bub1 inhibitor. With an IC50 of 680 nM for human Bub1 in the presence of 2 mM ATP.</p>Formule :C26H26F2N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :492.52Cyclotheonellazole A
CAS :<p>Cyclotheonellazole A inhibits elastase (IC50=0.034nM) & chymotrypsin (IC50=0.62nM), a natural macrocyclic peptide.</p>Formule :C44H54N9NaO14S2Couleur et forme :SolidMasse moléculaire :1020.07JTK-853
CAS :<p>JTK-853: novel non-nucleoside HCV polymerase inhibitor with strong antiviral activity (EC50: 0.38 μM genotype 1a, 0.035 μM 1b).</p>Formule :C28H23F7N6O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :704.64Z-PDLDA-NHOH
CAS :<p>Z-PDLDA-NHOH is a potent, specific vertebrate collagenase inhibitor [1].</p>Formule :C22H32N4O6Couleur et forme :SolidMasse moléculaire :448.51HIV-1 protease-IN-9
CAS :<p>HIV-1 protease-IN-9 (compound 5b), a potent HIV-1 protease inhibitor, exhibits strong antiviral efficacy with a dissociation constant (K_i) of 0.028 nM and a</p>Formule :C37H41N7O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :679.83DCLK1-IN-2
CAS :<p>DCLK1-IN-2 (Compound I-5) is a potent inhibitor of DCLK1, exhibiting an IC50 of 171.3 nM, and demonstrates significant antiproliferative effects on SW1990 cell</p>Formule :C26H32N8O3SCouleur et forme :SolidMasse moléculaire :536.65Berotralstat HCl
CAS :<p>Berotralstat HCl is a selective plasma kallikrein inhibitor, reducing pain and swelling in HAE by blocking bradykinin release.</p>Formule :C30H28Cl2F4N6OCouleur et forme :SolidMasse moléculaire :635.4886Z-DEVD-CMK
CAS :<p>Z-DEVD-CMK irreversibly inhibits various cathepsins in vitro [1].</p>Formule :C27H35ClN4O12Couleur et forme :SolidMasse moléculaire :643.04I-XW-053
CAS :<p>I-XW-053 is an inhibitor of capsid targeted HIV-1 replication using the hybrid structure based method to block the interface between CA N-terminal domains (NTD-</p>Formule :C22H16N2O2Degré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :340.37O-Benzoylhydroxylamine
CAS :<p>O-Benzoyl hydroxylamine exhibits properties as a dipeptidyl peptidase-IV (DPP-IV) inhibitor and demonstrates antidiabetic effects[1].</p>Formule :C7H7NO2Couleur et forme :SolidMasse moléculaire :137.14Kallikrein-IN-2
CAS :<p>Kallikrein-IN-2 (compound 1) is an inhibitor of the kinin-releasing enzyme Kallikrein.</p>Formule :C28H25F3N4O4Couleur et forme :SolidMasse moléculaire :538.52Neurodegenerative Disorder-Targeting Compound 1
CAS :<p>Neurodegenerative Disorder-Targeting Compound 1 is an inhibitor of calpain [1].</p>Formule :C28H28N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.55NCI-B16
CAS :<p>NCI-B16 is a small-molecule RNA binder that inhibits HCV (hepatitis C virus) replication [1].</p>Formule :C27H26N8O4Couleur et forme :SolidMasse moléculaire :526.55KCC009
CAS :<p>KCC009 is a potent and selective Transglutaminase 2 Inhibitor.</p>Formule :C21H22BrN3O5Couleur et forme :SolidMasse moléculaire :476.32SQ 32056
CAS :<p>SQ 32056 is a cathepsin E inhibitor.</p>Formule :C37H56N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :636.86BMS-189664 HCl
CAS :<p>BMS-189664 HCl is a selective and orally active thrombin active site inhibitor.</p>Formule :C22H35ClN6O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :515.07Ecallantide
CAS :<p>Ecallantide (DX-88) is a recombinant inhibitor specifically targeting plasma kallikrein, which serves to impede the synthesis of bradykinin.</p>Formule :C305H448N88O91S8Couleur et forme :SolidMasse moléculaire :7059.88Proteasome-IN-4
<p>Proteasome-IN-4, a potent non-covalent inhibitor (IC50=8.39nM), halts cancer cell growth, useful for oncology studies.</p>Formule :C44H58N6O5Couleur et forme :SolidMasse moléculaire :750.97MMP-145
CAS :<p>MMP-145 is used as a protease inhibitor.</p>Formule :C20H20N2O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :432.45HIV-1 protease-IN-8
CAS :<p>HIV-1 protease-IN-8 (compound 34b) is a potent inhibitor of the HIV-1 protease enzyme, exhibiting an IC50 of 0.32 nM.</p>Formule :C25H35N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :489.63Human enteropeptidase-IN-1
CAS :<p>Enteropeptidase-IN-1: orally active, potent inhibitor, low systemic exposure, for anti-obesity research.</p>Formule :C20H18N4O7Couleur et forme :SolidMasse moléculaire :426.38MeOSuc-AAPV-CMK
CAS :<p>MeOSuc-AAPV-CMK (Elastase Inhibitor III) serves as an inhibitor of elastase, as well as cathepsin G and proteinase 3, and impedes leukocyte elastase-mediated</p>Formule :C22H35ClN4O7Couleur et forme :SolidMasse moléculaire :502.99NK3201
CAS :<p>NK3201, a specific chymase inhibitor, suppresses bleomycin-induced pulmonary fibrosis in hamsters.</p>Formule :C31H29N5O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :567.59(1R,4S)-Yimitasvir diphosphate
CAS :<p>Yimitasvir diphosphate, also known as Emitasvir, is an orally-administered inhibitor of the hepatitis C virus (HCV) nonstructural protein 5A (NS5A).</p>Formule :C49H64N8O14P2Couleur et forme :SolidMasse moléculaire :1051.03Tyropeptin A-4
CAS :<p>Tyropeptin A-4 is used as a proteasome inhibitor.</p>Formule :C31H41N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :551.67BMS-189664
CAS :<p>BMS-189664 is an inhibitor of thrombin.</p>Formule :C22H34N6O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :478.61HCV-IN-44
CAS :<p>HCV-IN-44 (compound 28) is an inhibitor of the HCV NS5B protein, efficacious in suppressing HCV virus replication and useful for researching HCV infection [1].</p>Formule :C24H26FN3O5SCouleur et forme :SolidMasse moléculaire :487.54HCV-IN-43
CAS :<p>HCV-IN-43 (compound 2), an HCV NS5B protein inhibitor, efficiently inhibits HCV virus replication and is utilized in the study of HCV infection [1].</p>Formule :C26H26FN3O5SCouleur et forme :SolidMasse moléculaire :511.57Reverse transcriptase-IN-1
CAS :<p>Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent inhibitor of HIV-1 nonnucleoside reverse transcriptase with an IC50of 13.7</p>Formule :C25H17N7O2Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :447.45Cathepsin K inhibitor 3
CAS :<p>Cathepsin K inhibitor 3: Selective, IC50 of 0.5 nM, good pharmacokinetics, potential for OA research.</p>Formule :C30H31FN4O4SCouleur et forme :SolidMasse moléculaire :562.65Mergetpa
CAS :<p>Mergetpa, a carboxypeptidase inhibitor, impedes the conversion of kinins and B2 receptor antagonists into metabolites devoid of the C-terminal arginine [1].</p>Formule :C7H15N3O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :237.34Cathepsin Inhibitor 2
CAS :<p>Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: <20 nM).</p>Formule :C19H21F6N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.38LY52
CAS :<p>LY52 is a matrix metalloproteinase-2 inhibitor. It acts by suppressing tumor invasion and metastasis.</p>Formule :C22H24N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.45Atecegatran metoxil
CAS :<p>Atecegatran Metoxil (AZD0837), an oral thrombin inhibitor in development for stroke prevention in atrial fibrillation, is well-tolerated with favorable PK.</p>Formule :C22H23ClF2N4O5Couleur et forme :SolidMasse moléculaire :496.89HIV-1 protease-IN-11
CAS :<p>HIV-1 protease-IN-11 (compound 34a), an HIV-1 protease inhibitor, demonstrates potent inhibition with an IC50 of 0.41 nM and maintains substantial efficacy</p>Formule :C26H37N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :503.65MMP-3 Inhibitor VIII
CAS :<p>Matrix metalloproteinase-3 (MMP-3), also known as stromelysin-1, is a critical enzyme involved in tissue remodeling and repair through its role in degrading extracellular matrix proteins, facilitating cell migration. This enzyme has been implicated in various physiological processes including vascular remodeling associated with aneurysm formation, wound healing, the progression of atherosclerosis, and tumor initiation. MMP-3 inhibitor VIII, a cell-permeable sulfonamide-based hydroxamic acid, effectively inhibits MMP-3 by binding to its active site (Ki = 23 nM), thus blocking its enzymatic activity. Additionally, this inhibitor has been demonstrated to suppress the activity of mouse macrophage metalloelastase MME/MMP-12, with an IC50 value of 13 nM, highlighting its potential utility in research on tissue remodeling and disease processes involving MMPs.</p>Formule :C20H26N2O5SCouleur et forme :SolidMasse moléculaire :406.5Dim16
CAS :<p>Dim16, a dual inhibitor of PCSK9/HMG-CoAR, demonstrates potent activity with an IC50 of 19 nM against PCSK9 and significantly impedes PCSK9-LDLR interaction</p>Formule :C29H38IN5Couleur et forme :SolidMasse moléculaire :583.55DS-1040 Tosylate
CAS :<p>DS-1040 Tosylate is a thrombin-activated fibrinolysis inhibitor (TAFI) inhibitor and a fibrinolysis enhancer, used for researching thromboembolic diseases.</p>Formule :C23H35N3O5SCouleur et forme :SolidMasse moléculaire :465.61M867
CAS :<p>M867 is a selective, reversible caspase-3 inhibitor, possessing an IC50 of 1.4 nM and a Ki value of 0.7 nM, demonstrating anti-apoptotic activity [1].</p>Formule :C27H43N7O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :561.67LM-030
CAS :<p>LM-030, also known as BPR277, is a novel inhibitor of kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2).</p>Formule :C46H72N8O12Couleur et forme :SolidMasse moléculaire :929.11MMP-9 Inhibitor I
CAS :<p>MMP-9 inhibitor I is an inhibitor of matrix metalloproteinase-9 (MMP-9) that is selective over MMP-1 and MMP-13 (IC50s = 5, 1,050, and 113 nM, respectively).</p>Formule :C27H33N3O5SCouleur et forme :SolidMasse moléculaire :511.63M190S
CAS :<p>M109S is a novel small molecule that shields cells from mitochondria-dependent apoptosis, demonstrating effectiveness both in vitro and in vivo.</p>Formule :C21H21N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :375.42NS5A-IN-3
CAS :<p>NS5A-IN-3 is a potent NS5A inhibitor with high efficacy against HCV 1b, good activity on 3a, and strong metabolic stability; superior to daclatasvir.</p>Formule :C44H44N6O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :784.86PNU-103017
CAS :<p>PNU-103017 is an inhibitor of HIV protease.</p>Formule :C28H28N2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :504.6L-689502
CAS :<p>L-689502 is a potent HIV-l protease inhibitor (IC50: 1 nM).</p>Formule :C39H51N3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :673.84GSK-625433
CAS :<p>GSK-625433: Homochiral inhibitor blocks HCV genotypes 1a/1b polymerase.</p>Formule :C26H32N4O5SCouleur et forme :SolidMasse moléculaire :512.62Petesicatib
CAS :<p>Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases.</p>Formule :C25H23F6N5O4SDegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :603.54SID 26681509
CAS :<p>SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM).</p>Formule :C27H33N5O5SDegré de pureté :98.16%Couleur et forme :SolidMasse moléculaire :539.65MMP3 inhibitor 1
CAS :<p>MMP3 inhibitor 1 is a potent and highly selective inhibitor of MMP-3 (IC50 of 1 nM).</p>Formule :C23H31N3O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.57FK706
CAS :<p>FK706, a human neutrophil elastase inhibitor (IC50: 83 nM, Ki: 4.2 nM), also blocks mouse and porcine elastases. Anti-inflammatory.</p>Formule :C26H33F3N4NaO7Couleur et forme :SolidMasse moléculaire :593.556PDDC inhibitor
CAS :<p>PDDC inhibitor (Phenyl (R)-(1-(3-(3,4-dimethoxyphenyl)-2,6-dimethylimidazo[1,2-b]pyridazin-8-yl)pyrrolidin-3-yl)carbamate) is an nSMase2 inhibitor.</p>Formule :C27H29N5O4Degré de pureté :96.09% - 99.39%Couleur et forme :SolidMasse moléculaire :487.55Filibuvir
CAS :<p>Filibuvir (PF-00868554) inhibits HCV polymerase genotypes 1a/1b, EC50s 59 nM.</p>Formule :C29H37N5O3Degré de pureté :99.28% - >99.99%Couleur et forme :SolidMasse moléculaire :503.64Ac-YVAD-AOM
CAS :<p>Ac-YVAD-AOM is a selective and potent caspase-1 inhibitor showing antitumor activity and potential analgesic activity.</p>Formule :C33H42N4O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :654.71Collagen proline hydroxylase inhibitor-1
CAS :<p>Collagen proline hydroxylase inhibitor-1 具有抗纤维增生活性。</p>Formule :C24H21N5O4Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :443.45ZED-1227
CAS :<p>ZED-1227 (TAK-227) is a TG2 inhibitor with anticancer activity that blocks inflammation-induced TG2 expression and activation for the treatment of Celiac Diseas</p>Formule :C26H36N6O6Degré de pureté :99.04%Couleur et forme :SolidMasse moléculaire :528.6γ-Glu-Tyr
CAS :<p>gamma-Glu-Tyr (gamma-Glutamyltyrosine) is a kokumi peptide against dipeptidyl peptidase-IV (DPP-IV) and is used in the study of diabetes mellitus.</p>Formule :C14H18N2O6Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :310.3HIV-1 inhibitor-54
CAS :<p>HIV-1 inhibitor-54: potent anti-HIV (EC50: 32 nM), targets WT HIV-1 IIIB in MT-4 cells for infection research.</p>Formule :C27H30N6O4SDegré de pureté :98.05% - 99.44%Couleur et forme :SoildMasse moléculaire :534.63Aderamastat
CAS :<p>Aderamastat (FP-025) is an orally active matrix metalloproteinase 12 (MMP-12) inhibitor indicated for the study of allergic asthma, COPD and pulmonary fibrosis.</p>Formule :C21H18N2O4SDegré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :394.44Nesbuvir
CAS :<p>Nesbuvir: HCV NS5B polymerase inhibitor, IC50 9 nM against HCV 1b replicon in liver cancer cells.</p>Formule :C22H23FN2O5SDegré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :446.49BMS-212122
CAS :<p>BMS-212122 inhibits MTP, reduces lipids and plaque in animal tests.</p>Formule :C43H36F6N4O2Degré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :754.76MK-0674
CAS :<p>MK-0674 is a cathepsin K inhibitor (IC50: 0.4 nM) that inhibits Cat B, Cat F, Cat L, and Cat S for metabolism-related diseases.</p>Formule :C26H27F6N3O2Degré de pureté :97.3% - 99.91%Couleur et forme :SolidMasse moléculaire :527.5VBY-825
CAS :<p>VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.</p>Formule :C23H29F4N3O5SDegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :535.55HCV NS5B polymerase-IN-2
CAS :<p>HCVNS5B polymerase-IN-2 (Compound 298) is an inhibitor of the Ns5b polymerase. It holds potential for research into the treatment of hepatitis C virus (HCV) infections.</p>Formule :C26H24N2O4Couleur et forme :SolidMasse moléculaire :428.48(2R,3S)-Emricasan
CAS :<p>(2R,3S)-Emricasan ((2R,3S)-PF 03491390) is an isomer of Emricasan. This compound acts as an orally effective irreversible pan-caspase inhibitor. (2R,3S)-Emricasan inhibits the increase in caspase-3 activity induced by Zika virus (ZIKV) and protects human cortical neural progenitor cells.</p>Formule :C26H27F4N3O7Couleur et forme :SolidMasse moléculaire :569.5Beclabuvir
CAS :<p>Beclabuvir blocks HCV NS5B polymerase at thumb site 1, effective on genotypes 1, 3, 4, 5 with IC50 <28 nM.</p>Formule :C36H45N5O5SDegré de pureté :99.87% - 99.93%Couleur et forme :SolidMasse moléculaire :659.84Immunoproteasome activator 1
CAS :<p>Immunoproteasome Activator 1 (compound A) is a selective immunoproteasome activator that enhances the presentation of individual MHC-I binding peptides by over 100 times. It binds to the proteasomal structural subunit PSMA1 and facilitates the association of the proteasome activators PA28α/β (PSME1/PSME2) with the immunoproteasome.</p>Formule :C24H23N3O3Couleur et forme :SolidMasse moléculaire :401.46UK-370106
CAS :<p>UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-</p>Formule :C35H44N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :572.73Isobutylamido thiazolyl resorcinol
CAS :<p>Isobutylamido thiazolyl resorcinol is a tyrosinase (Tyrosinase) inhibitor that prevents pigment deposition induced by ultraviolet radiation.</p>Formule :C13H14N2O3SCouleur et forme :SolidMasse moléculaire :278.33LK-732
CAS :<p>LK-732 is a thrombin inhibitor with antithrombotic activity. It exhibits dose-dependent inhibition in models of hypercoagulability, with an IC50 value of 1.3 mg/kg. LK-732 is used in cardiovascular and cerebrovascular research.</p>Formule :C25H29N5O3SCouleur et forme :SolidMasse moléculaire :479.59Boc3Arg
<p>Boc 3 Arg is a tert-butyl carbamate-protected arginine compound. It serves as an efficient tag that induces degradation by directly targeting proteins to the 20S proteasome.</p>Formule :C21H39N5O7Couleur et forme :SolidMasse moléculaire :473.563-Aminobenzene-1,2-diol
CAS :<p>3-Aminobenzene-1,2-diol (compound C8) is an inhibitor of matrix metalloproteinases (MMP), with IC50 values of 20, 26, 16, and 16.3 μM against MMP-2, MMP-8, MMP-9, and MMP-14, respectively.</p>Formule :C6H7NO2Couleur et forme :SolidMasse moléculaire :125.13TGase2-IN-1
CAS :<p>TGase2-IN-1 (Compound 22) is an orally effective TGase2 inhibitor with an IC50 of 1.12 µM. It inhibits TGase2 in human retinal microvascular endothelial cells with a strikingly lower IC50 of 0.07 µM. The oral bioavailability of TGase2-IN-1 is 74.6%. Additionally, it can suppress retinal vascular leakage in a mouse model of diabetes induced by Streptozotocin.</p>Formule :C23H25N3O3Couleur et forme :SolidMasse moléculaire :391.46Tyrosinase-IN-39
<p>Tyrosinase-IN-39 (compound 5r) is a competitive inhibitor of tyrosinase, with an IC50 of 6.4 μM, and is used in the study of skin diseases.</p>Formule :C23H19N5O4S2Couleur et forme :SolidMasse moléculaire :493.56SCO-792
<p>SCO-792: potent, reversible oral enteropeptidase inhibitor, with slow in vitro dissociation and in vivo protein digestion blocking.</p>Formule :C22H22N4O8·xH2OCouleur et forme :SolidPNU-248686A
CAS :<p>PNU-248686A is an inhibitor of matrix metalloproteinase (MMP).</p>Formule :C22H18ClNaO5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.95CM-352
CAS :<p>CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage.</p>Formule :C24H29N3O6SDegré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :487.57DPP-4-IN-15
CAS :<p>DPP-4-IN-15 (Compound 22) is a non-competitive inhibitor of dipeptidyl peptidase-4 (DPP-4) with an IC50 value of 8.24 μM.</p>Formule :C17H14F3N3O2SCouleur et forme :SolidMasse moléculaire :381.372UK 356618
CAS :<p>UK 356618 is a potent and selective inhibitor of matrix metalloprotease-3 (IC50: 5.9 nM).</p>Formule :C34H43N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :557.72Verducatib
CAS :<p>Verducatib is an inhibitor of cathepsins (cathepsin).</p>Formule :C31H35FN4O3Couleur et forme :SolidMasse moléculaire :530.633Anti-infective agent 10
CAS :<p>Anti-infective agent 10 (Compound Example 30) is an ns5b polymerase inhibitor that functions as an anti-HCV agent.</p>Formule :C26H25N3O7SCouleur et forme :SolidMasse moléculaire :523.56HCV-IN-40
CAS :<p>HCV-IN-39 is a potent oral drug inhibiting HCV, effective on GT1a (EC50: 0.259μM), GT1b (EC50: 0.434μM), GT1b CES1 (EC50: 0.069μM) replicons.</p>Formule :C21H26BrFN3O9PCouleur et forme :SolidMasse moléculaire :594.32RBx-0597
CAS :<p>RBx-0597 is a selective DPP-IV inhibitor with IC50 values of 32 nM, 31 nM, and 39 nM for human, mouse, and rat plasma DPP-IV, respectively. It is utilized in research focused on type 2 diabetes.</p>Formule :C19H20F2N4O2Couleur et forme :SolidMasse moléculaire :374.384GB111-NH2
CAS :<p>GB111-NH2, a cysteine cathepsin inhibitor, is applicable in cancer research [1].</p>Formule :C33H39N3O6Couleur et forme :SolidMasse moléculaire :573.68Marizomib
CAS :<p>Marizomib is a novel irreversible brain-permeable proteasome inhibitor that inhibits CT-L, CT-T-laspase-like, and trypsin-like 20S proteasomes.Cost-effective and quality-assured.</p>Formule :C15H20ClNO4Degré de pureté :98.03% - 99.41%Couleur et forme :SolidMasse moléculaire :313.78GSK5852
<p>GSK5852, an HCV NS5B inhibitor, has IC50 of 50 nM; potently fights HCV with EC50 of 3.0 nM for GT1a and 1.7 nM for GT1b.</p>Formule :C27H27BF2N2O6SCouleur et forme :SolidMasse moléculaire :556.39Odiparcil
CAS :<p>Odiparcil is an orally active beta-d-thioxyloside analog.</p>Formule :C15H16O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.35BI-1942
CAS :<p>BI-1942 is a chymase inhibitor with an IC50 value of 0.4 nM against human chymase. It is applicable for research in ophthalmic diseases.</p>Formule :C24H26N4O4Couleur et forme :SolidMasse moléculaire :434.488Freselestat quarterhydrate
<p>ONO-6818 quarterhydrate: oral neutrophil elastase inhibitor, Ki 12.2 nM; >100x less effective on other proteases; strong anti-inflammatory.</p>Formule :C23H30N6O5Couleur et forme :SolidMasse moléculaire :457.03Plodicitinib
CAS :<p>Plodicitinib is an inhibitor of Janus tyrosine kinase 3/TEC family kinase, exhibiting anti-inflammatory properties.</p>Formule :C19H22FN7O2Couleur et forme :SolidMasse moléculaire :399.422CatD-IN-1
CAS :<p>CatD-IN-1 (Compound 5) is a Cathepsin D inhibitor with an IC50 of 0.44 μM, and it shows potential for research in the field of osteoarthritis.</p>Formule :C18H18Cl2N4O5Couleur et forme :SolidMasse moléculaire :441.265Matriptase-IN-2 free base
CAS :<p>Matriptase-IN-2 free base, a matriptase inhibitor with a K i of 5 nM, has potential applications in musculoskeletal system disorder research (WO2011023958A1; compound 432) [1].</p>Formule :C29H33Cl2N5O3SCouleur et forme :SolidMasse moléculaire :602.58GLS-1-IN-1
<p>GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor that inhibits Hep G2, MCF 7 and MCF 10A cells.</p>Formule :C26H25FN4OSCouleur et forme :SolidMasse moléculaire :460.57Valopicitabine
CAS :<p>Valopicitabine is an effective prodrug of the effective anti-HCV drug 2'-C-methylcytidine and can be used as a promising antiviral drug for the study of chronic</p>Formule :C15H24N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.37SSR-182289A (Free)
CAS :<p>SSR-182289A (Free) is a thrombin inhibitor.</p>Formule :C30H33F2N5O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :597.68BMT-052
CAS :<p>BMT-052 is a potent and selective Pan-genotypic HCV NS5B Polymerase Inhibitor (EC50 = 7 nM).</p>Formule :C30H17D9F4N6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :635.61Tilpisertib fosmecarbil
CAS :<p>Tilpisertib fosmecarbil is a potent inhibitor of serine/threonine kinases with anti-inflammatory properties.</p>Formule :C35H36ClN8O7PCouleur et forme :SolidMasse moléculaire :747.14Monosodium 2-sulfoterephthalate
CAS :<p>Monosodium 2-sulfoterephthalate (8) is an inhibitor of glutamate carboxypeptidase II.</p>Formule :C8H5NaO7SCouleur et forme :SolidMasse moléculaire :268.176Idraparinux Na
CAS :<p>Idraparinux Na is an Antithrombotic, Indirect, Selective, Synthetic Factor Xa Inhibitor</p>Formule :C38H55Na9O49S7Couleur et forme :SolidMasse moléculaire :1727.14HCV-IN-7
CAS :<p>HCV-IN-7: potent oral HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.</p>Formule :C40H48N8O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :768.92Tyrosinase-IN-37
CAS :<p>Tyrosinase-IN-37 (Compound 3c) is a potent inhibitor of tyrosinase, with an IC50 value of 1.02 μM, which is 14 times more effective than kojic acid (IC50 of 14.74 μM). This compound effectively prevents the browning of Rosa roxburghii and can also inhibit browning not caused by tyrosinase.</p>Formule :C12H12N6SCouleur et forme :SolidMasse moléculaire :272.33BI 224436
CAS :<p>BI 224436 is an inhibitor of HIV-1 noncatalytic site integrase. With EC50 values of less than 15 nM against different HIV-1 laboratory strains.</p>Formule :C27H26N2O4Couleur et forme :SolidMasse moléculaire :442.51ZINC09518833
CAS :<p>ZINC09518833 is an α-ketoamide non-peptide proteasome inhibitor with an IC50 value of 12.4 μM. It can bind with both the active and inactive sites of the proteasome. ZINC09518833 shows promise for use in research related to multiple myeloma (MM).</p>Formule :C24H25N3O5Couleur et forme :SolidMasse moléculaire :435.47Napsagatran hydrate
CAS :<p>Napsagatran hydrate is a novel and specific inhibitor of thrombin.</p>Formule :C26H36N6O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :576.66Dup-714
CAS :<p>Dup-714 is a thrombin inhibitor.</p>Formule :C21H33BN6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :460.33Feniralstat
CAS :<p>Feniralstat (KVD-824) is a selective and potent kallikrein (kallikrein) inhibitor, useful in immune system diseases and cardiovascular disease research.</p>Formule :C26H25F2N5O4Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :509.51M826
<p>M826, a non-peptide, potent, selective, and reversible caspase-3 inhibitor, exhibits an IC50 of 0.005 μM and demonstrates strong anti-apoptotic activity in</p>Formule :C28H45N7O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :575.7Cathepsin K inhibitor 2
CAS :<p>Cathepsin K inhibitor 2 targets CTSK gene, may treat osteoporosis and osteoarthritis, detailed in patent WO2021147882A1.</p>Formule :C30H33F4N5O3Couleur et forme :SolidMasse moléculaire :587.61(2S,4R)-Teneligliptin
CAS :<p>(2S,4R)-Teneligliptin is a selective inhibitor of dipeptidyl peptidase IV (DPP-4). It increases the concentration of active glucagon-like peptide-1 (GLP-1) in plasma, which in turn stimulates insulin secretion when blood glucose levels are elevated, thereby exhibiting hypoglycemic effects. (2S,4R)-Teneligliptin is a promising candidate for research in type 2 diabetes.</p>Formule :C22H30N6OSCouleur et forme :SolidMasse moléculaire :426.578Kallikrein-IN-1
CAS :<p>Kallikrein-IN-1 (Formula A) is an inhibitor of the kinin-releasing enzyme Kallikrein.</p>Formule :C28H26FN5O4Couleur et forme :SolidMasse moléculaire :515.54TCL1
CAS :<p>TCL1 acts as a selective non-covalent inhibitor targeting the Pru domain of the Rpn-13 subunit within the 19S regulatory particle (19S RP) of the proteasome, with an IC50 value around 26 μM. It disrupts the recognition and transport of ubiquitinated proteins by Rpn-13, thus inhibiting proteasomal degradation and affecting intracellular protein metabolism balance. TCL1 holds potential for research in hematologic malignancies.</p>Formule :C19H14BrClN4O2SCouleur et forme :SolidMasse moléculaire :477.762Cathepsin C-IN-5
CAS :<p>Cathepsin C-IN-5 (SF38) is a potent, oral Cathepsin C blocker with an IC50 of 59.9 nM; less active against Cat L/S/B/K; has anti-inflammatory effects.</p>Formule :C21H17ClN6OSCouleur et forme :SolidMasse moléculaire :436.92GSK-2878175
CAS :<p>GSK-2878175, a NS5B inhibitor, is used potentially for the treatment of HCV infection.</p>Formule :C27H23BClFN2O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :568.81Piceid 6″-O-azelaic acid ester
<p>Piceid 6″-O-azelaic acid ester exhibited strong intracellular tyrosinase inhibition and decolorization activity.</p>Formule :C24H36O10Couleur et forme :SolidMasse moléculaire :484.54ABT-072
CAS :<p>ABT-072 is a nonnucleoside NS5B polymerase inhibitor and a candidate drug evaluated for treatment of hepatitis C virus.</p>Formule :C24H27N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :469.55Cyclophilin inhibitor 1
CAS :<p>Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.</p>Formule :C31H39N5O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :593.67Ciluprevir
CAS :<p>Ciluprevir is a selective HCV NS3 protease inhibitor, effective against non-genotype-1 HCV; less potent for genotypes 2/3.</p>Formule :C40H50N6O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :774.93MK-8876
CAS :<p>MK-8876 is an Inhibitor of HCV NS5B Site D.</p>Formule :C32H24F2N4O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :614.62GW311616
CAS :<p>GW-311616 is a long duration, orally bioavailable, and selective human neutrophil elastase (HNE) inhibitor (IC50: 22 nM; Ki: 0.31 nM).</p>Formule :C19H31N3O4SCouleur et forme :SolidMasse moléculaire :397.53MeO-Suc-Ala-Ala-Pro-Ala-CMK
CAS :<p>MeO-Suc-Ala-Ala-Pro-Ala-CMK (MSACK) is an inhibitor of human neutrophil elastase (HNE) with an IC50 of 20.3 μM. It effectively inhibits the hydrolysis of substrates like lung tissue elastin by HNE and is applicable in studies related to conditions such as chronic obstructive pulmonary disease (COPD).</p>Formule :C20H31ClN4O7Couleur et forme :SolidMasse moléculaire :474.936RIPK1-IN-26
CAS :<p>RIPK1-IN-26 is a potent inhibitor of Receptor-Interacting Serine/Threonine Kinase 1 (RIPK1), exhibiting anti-necrotic properties in cells. This compound demonstrates good metabolic stability and binding specificity in mice. RIPK1-IN-26 holds potential for development as a PET imaging probe and in the research of neurodegenerative diseases.</p>Formule :C15H20FNO2Couleur et forme :SolidMasse moléculaire :265.32Freselestat
CAS :<p>Freselestat (ONO-6818) inhibits neutrophil elastase, reduces interleukin 8, C5B-9, and inflammation in cardiopulmonary bypass.</p>Formule :C23H28N6O4Couleur et forme :SolidMasse moléculaire :452.51TMPRSS6-IN-1 TFA
<p>TMPRSS6-IN-1 (TFA) is a potent inhibitor of TMPRSS6 (Matriptase-2), a member of the TTSP family (a type of transmembrane serine protease). TMPRSS6 is a type II TTSP, and genetically reduced levels of TMPRSS6 have been shown to improve symptoms of hemochromatosis and β-thalassemia in mice.</p>Formule :C35H41F3N8O6S2Couleur et forme :SolidMasse moléculaire :790.875JBJ-08-178-01
CAS :<p>JBJ-08-178-01, a mutant-selective tyrosine kinase inhibitor, targets (HER2) human epidermal growth factor receptor 2 and exhibits antitumoral activity. This compound not only diminishes HER2's kinase activity and protein levels through the induction of proteasomal degradation of the receptor but also shows promise in non-small-cell lung cancer research.</p>Formule :C31H30N8O3Couleur et forme :SolidMasse moléculaire :562.62
