Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
1427 produits trouvés pour "Autophagie"
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TOMATIDINE HYDROCHLORIDE
CAS :<p>Tomatidine hydrochloride (Tomatidine HCl) is a steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway.</p>Formule :C27H46ClNO2Degré de pureté :99.75% - ≥95%Couleur et forme :SolidMasse moléculaire :452.11Triptonide
CAS :<p>Triptonide treats autoimmune diseases, has antileukemic/tumor effects, is anti-inflammatory, and boosts IL-37.</p>Formule :C20H22O6Degré de pureté :99.11% - 99.64%Couleur et forme :White Crystalline PowderMasse moléculaire :358.39Leonurine hydrochloride
CAS :<p>Leonurine hydrochloride (SCM-198 hydrochloride) , a major alkaloid compound extracted from Leonurus japonicas Houtt.</p>Formule :C14H22ClN3O5Degré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :347.79Rhoifolin
CAS :<p>Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.</p>Formule :C27H30O14Degré de pureté :98.11% - 98.58%Couleur et forme :SolidMasse moléculaire :578.52palovarotene
CAS :<p>Palovarotene (Ro 3300074) is an agonist of nuclear retinoic acid receptor γ (RAR-γ).</p>Formule :C27H30N2O2Degré de pureté :97.88% - 98.05%Couleur et forme :SolidMasse moléculaire :414.54C646
CAS :<p>C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).</p>Formule :C24H19N3O6Degré de pureté :98% - 99.21%Couleur et forme :SolidMasse moléculaire :445.42SB 239063
CAS :<p>SB 239063 (SB239063) is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 nM, showing no activity against the γ- and δ-kinase isoforms.</p>Formule :C20H21FN4O2Degré de pureté :99.42% - 99.81%Couleur et forme :SolidMasse moléculaire :368.4Azithromycin
CAS :<p>Azithromycin (CP 62993) is a macrolide antibiotic that primarily targets the 50S subunit of bacterial ribosomes. High-Quality, Low-Cost!</p>Formule :C38H72N2O12Degré de pureté :99.9% - 99.97%Couleur et forme :White To Off-White Solid CrystallineMasse moléculaire :748.98Silmitasertib
CAS :<p>Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM).</p>Formule :C19H12ClN3O2Degré de pureté :98% - 99.90%Couleur et forme :SolidMasse moléculaire :349.77Scriptaid
CAS :<p>Scriptaid (GCK1026) is an inhibitor of HDAC, and has a greater effect on acetylated H4 than H3.</p>Formule :C18H18N2O4Degré de pureté :96.74% - 99.45%Couleur et forme :SolidMasse moléculaire :326.354E1rcat
CAS :<p>4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.</p>Formule :C28H18N2O6Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :478.45Hemin
CAS :<p>Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.</p>Formule :C34H32ClFeN4O4Degré de pureté :97.169% - 99.59%Couleur et forme :Dark Purple Crystalline PowderMasse moléculaire :651.94β-Lapachone
CAS :<p>β-Lapachone (ARQ-501) is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase.</p>Formule :C15H14O3Degré de pureté :99.76% - 99.88%Couleur et forme :SolidMasse moléculaire :242.27DAPT
CAS :<p>DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active.</p>Formule :C23H26F2N2O4Degré de pureté :98.06% - 99.81%Couleur et forme :White SolidMasse moléculaire :432.46Ginsenoside Rb1
CAS :<p>Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.</p>Formule :C54H92O23Degré de pureté :99.12% - 99.76%Couleur et forme :SolidMasse moléculaire :1109.29SB225002
CAS :<p>SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.</p>Formule :C13H10BrN3O4Degré de pureté :98.16% - 99.85%Couleur et forme :SolidMasse moléculaire :352.14FC131 TFA (606968-52-9 free base)
CAS :<p>FC131 TFA (606968-52-9 free base) (FC131 TFA) is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hiv</p>Formule :C38H48F3N11O8Degré de pureté :99.39% - 99.67%Couleur et forme :SolidMasse moléculaire :843.85ATI-2341 acetate(1337878-62-2 free base)
<p>ATI-2341 acetate is an effective allosteric agonist of CXCR4, it activates Gα1 instead of Gα13.</p>Formule :C106H182N26O27S2Degré de pureté :97.14%Couleur et forme :SolidMasse moléculaire :2316.87Idelalisib
CAS :<p>Idelalisib (GS-1101) is a small molecule inhibitor of the PI3K catalytic subunit p110δ (IC50: 2.5 nM).</p>Formule :C22H18FN7ODegré de pureté :98% - 99.39%Couleur et forme :SolidMasse moléculaire :415.42MSX-122
CAS :<p>MSX-122 is a novel small molecule and partial CXCR4 antagonist, with potent inhibition of CXCR4/CXCL12 actions(IC50 = 10 nM).</p>Formule :C16H16N6Degré de pureté :98.31% - 98.94%Couleur et forme :SolidMasse moléculaire :292.34Acacetin
CAS :<p>Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidant</p>Formule :C16H12O5Degré de pureté :96.26% - ≥95%Couleur et forme :Pale-Yellow NeedlesMasse moléculaire :284.26Danirixin
CAS :<p>Danirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).</p>Formule :C19H21ClFN3O4SDegré de pureté :99.78% - >99.99%Couleur et forme :SolidMasse moléculaire :441.9Navarixin
CAS :<p>Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophil</p>Formule :C21H23N3O5Degré de pureté :98% - 99.51%Couleur et forme :SolidMasse moléculaire :397.42PD 169316
CAS :<p>PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.</p>Formule :C20H13FN4O2Degré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :360.34Cyclovirobuxine D
CAS :<p>Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.</p>Formule :C26H46N2ODegré de pureté :97.78% - 98%Couleur et forme :SolidMasse moléculaire :402.66AMD 3465 hexahydrobromide
CAS :<p>AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity.</p>Formule :C24H44Br6N6Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :896.07SB-265610
CAS :<p>SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist.</p>Formule :C14H9BrN6ODegré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :357.16ML339
CAS :<p>ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.</p>Formule :C26H32ClN3O5Degré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :502AMD-070 hydrochloride
CAS :<p>AMD-070 hydrochloride is a CXCR4 antagonist, is useful for Anti HIV.</p>Formule :C21H28ClN5Degré de pureté :98.38% - 98.57%Couleur et forme :SolidMasse moléculaire :385.93CTCE 9908 acetate
<p>CTCE 9908 acetate is an antagonist of CXCR4 and inhibits migration in CXCR4-expressing ovarian cancer cells.</p>Formule :C88H151N27O25Degré de pureté :98.47%Couleur et forme :SolidMasse moléculaire :1987.31MSX-127
CAS :<p>MSX-127 elicites positive response in peptide CXCR4.</p>Formule :C16H24N2O4Degré de pureté :98.43%Couleur et forme :SolidMasse moléculaire :308.37WZ811
CAS :<p>WZ811 is a novel and effective small molecular CXCR4 antagonist (EC50: 0.3 nM).</p>Formule :C18H18N4Degré de pureté :99.42% - ≥95%Couleur et forme :SolidMasse moléculaire :290.36Tenovin-1
CAS :<p>Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination.</p>Formule :C20H23N3O2SDegré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :369.48USL311
CAS :<p>USL311 blocks CXCR4/SDF-1 interaction, inhibits tumor cell growth and migration.</p>Formule :C24H34N6ODegré de pureté :98.46% - 99.56%Couleur et forme :SolidMasse moléculaire :422.57TAK-779
CAS :<p>TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).</p>Formule :C33H39ClN2O2Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :531.13Polyphyllin I
CAS :<p>Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,</p>Formule :C44H70O16Degré de pureté :98% - 99.5%Couleur et forme :SolidMasse moléculaire :855.02JMS-17-2
CAS :<p>JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).</p>Formule :C25H26ClN3ODegré de pureté :98.7% - 99.44%Couleur et forme :SolidMasse moléculaire :419.95TC14012 acetate
<p>TC14012 acetate is a serum-stable derivative of T140 which is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM.</p>Formule :C92H144N34O21S2Degré de pureté :98.33% - 99.71%Couleur et forme :SolidMasse moléculaire :2126.47MSX-130
CAS :<p>MSX-130 is CXCR4 Antagonist.</p>Formule :C36H26N4Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :514.62GSK621
CAS :<p>GSK621 is a specific and potent AMPK activator.</p>Formule :C26H20ClN3O5Degré de pureté :97.02% - 97.05%Couleur et forme :SolidMasse moléculaire :489.91Mirdametinib
CAS :<p>Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity.</p>Formule :C16H14F3IN2O4Degré de pureté :99.11% - 99.63%Couleur et forme :White PowderMasse moléculaire :482.19GW 4064
CAS :<p>GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).</p>Formule :C28H22Cl3NO4Degré de pureté :98% - 99.94%Couleur et forme :SolidMasse moléculaire :542.84SRT3109
CAS :<p>SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.</p>Formule :C18H23F2N5O4S2Degré de pureté :99.65% - 99.92%Couleur et forme :SolidMasse moléculaire :475.53Pyriproxyfen
CAS :<p>Pyriproxyfen (S-31183) is an insecticide that acts as a biomimetic of juvenile hormone.</p>Formule :C20H19NO3Degré de pureté :99.83%Couleur et forme :Solid CompactMasse moléculaire :321.37Plerixafor
CAS :<p>Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.</p>Formule :C28H54N8Degré de pureté :99.17% - >99.99%Couleur et forme :SolidMasse moléculaire :502.78AZD-5069
CAS :<p>AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).</p>Formule :C18H22F2N4O5S2Degré de pureté :98.38% - 98.63%Couleur et forme :SolidMasse moléculaire :476.52Plerixafor octahydrochloride
CAS :<p>Plerixafor octahydrochloride mobilizes HSCs by blocking SDF-1alpha/CXCR4 interaction, facilitating their release into circulation.</p>Formule :C28H62Cl8N8Degré de pureté :98.01% - 99.79%Couleur et forme :SolidMasse moléculaire :794.46SX-682
CAS :<p>SX-682 is an orally available allosteric inhibitor of CXCR1 and CXCR2.Cost-effective and quality-assured.</p>Formule :C19H14BF4N3O4SDegré de pureté :98.19% - 99.57%Couleur et forme :SolidMasse moléculaire :467.2ZSTK474
CAS :<p>PI3K Inhibitor ZSTK474 is an orally available, s-triazine derivative, ATP-competitive phosphatidylinositol 3-kinase (PI3K) inhibitor with potential</p>Formule :C19H21F2N7O2Degré de pureté :98.29% - 99.95%Couleur et forme :White PowderMasse moléculaire :417.41BX795
CAS :<p>BX795 selectively inhibits PDK1 (IC50: 6 nM), 140x over PKA, 1600x over PKC, 100x over GSK3β in cell-free assays.</p>Formule :C23H26IN7O2SDegré de pureté :98% - 99.57%Couleur et forme :SolidMasse moléculaire :591.47Isobavachalcone
CAS :<p>Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury in</p>Formule :C20H20O4Degré de pureté :98% - 99.76%Couleur et forme :SolidMasse moléculaire :324.37Oxyresveratrol
CAS :<p>1.</p>Formule :C14H12O4Degré de pureté :98.09% - 99.69%Couleur et forme :Yellow SolidMasse moléculaire :244.24HG-10-102-01
CAS :<p>HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).</p>Formule :C17H20ClN5O3Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :377.83NVP-AEW541
CAS :<p>NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-based</p>Formule :C27H29N5ODegré de pureté :98.7% - 99.86%Couleur et forme :SolidMasse moléculaire :439.55Lucanthone
CAS :<p>Lucanthone (Lucanthonum) is an inhibitor of Apurinic endonuclease-1 (APE-1).</p>Formule :C20H24N2OSDegré de pureté :99.92%Couleur et forme :Yellow Crystals From Alcohol SolidMasse moléculaire :340.48Enzastaurin
CAS :<p>Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.</p>Formule :C32H29N5O2Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :515.6MRT68921 HCl
CAS :<p>MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM, respectively).</p>Formule :C25H34N6O·HClDegré de pureté :99.86% - 99.98%Couleur et forme :SolidMasse moléculaire :471.04Schisandrin
CAS :<p>Schisandrin (Wuweizi alcohol-A) is a compound with anti-asthmatic, anti-cancer, and anti-inflammatory effects.</p>Formule :C24H32O7Degré de pureté :98.97% - 99.32%Couleur et forme :White PowderMasse moléculaire :432.51Pennogenin 3-O-β-chacotrioside
CAS :<p>Pennogenin 3-O-beta-chacotrioside from Paris polyphylla fights colorectal cancer, boosting autophagy proteins LC3 and Beclin-1.</p>Formule :C45H72O17Degré de pureté :99.69% - 99.77%Couleur et forme :SolidMasse moléculaire :885.04RITA
CAS :<p>RITA (NSC-652287) forms DNA-DNA/protein cross-links without DNA breaks; disrupts p53/Mdm2 like nutlin-3.</p>Formule :C14H12O3S2Degré de pureté :98.49% - 99.55%Couleur et forme :SolidMasse moléculaire :292.374EGI-1
CAS :<p>4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 μM).</p>Formule :C18H12Cl2N4O4SDegré de pureté :96.8% - 99.12%Couleur et forme :SolidMasse moléculaire :451.28Bortezomib
CAS :<p>Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.</p>Formule :C19H25BN4O4Degré de pureté :97.79% - >99.99%Couleur et forme :Yellow SolidMasse moléculaire :384.24CZC-25146 hydrochloride
CAS :<p>CZC-25146 is a selective LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2, respectively.</p>Formule :C22H26ClFN6O4SDegré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :525Danshensu
CAS :<p>Danshensu (Dan shen suan A) is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.</p>Formule :C9H10O5Degré de pureté :98.4% - 99.74%Couleur et forme :SolidMasse moléculaire :198.17SKF-96365 hydrochloride
CAS :<p>SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y</p>Formule :C22H27ClN2O3Degré de pureté :99.47% - 99.92%Couleur et forme :SolidMasse moléculaire :402.91Vitexin
CAS :<p>Vitexin: antinociceptive, antispasmodic, antioxidant, affects CYP enzymes, may inhibit cancer metastasis, protects brain.</p>Formule :C21H20O10Degré de pureté :98.13% - 99.64%Couleur et forme :Yellow PowderMasse moléculaire :432.3810074-G5
CAS :<p>10074-G5 is an inhibitor of c-Myc-Max dimerization.</p>Formule :C18H12N4O3Degré de pureté :99.51% - 99.67%Couleur et forme :SolidMasse moléculaire :332.31KN-93
CAS :<p>KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase.</p>Formule :C26H29ClN2O4SDegré de pureté :99.56% - 99.86%Couleur et forme :White SolidMasse moléculaire :501.04Taxifolin
CAS :<p>Taxifolin (Dihydroquercetin) is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.</p>Formule :C15H12O7Degré de pureté :94.91% - 98.9%Couleur et forme :Yellowish PowderMasse moléculaire :304.25Vinorelbine ditartrate
CAS :<p>Vinorelbine ditartrate (KW-2307) is a natural alkaloid and an anti-mitotic agent. Vinorelbine ditartrate has anti-tumor activity. Cost-effective and quality-assured.</p>Formule :C45H54N4O8·2C4H6O6Degré de pureté :98% - 99.86%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :1079.11UNBS5162
CAS :<p>UNBS5162 (UNBS-5162) is a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers.</p>Formule :C17H18N4O3Degré de pureté :98.37% - 99.97%Couleur et forme :SolidMasse moléculaire :326.35RAF265
CAS :<p>RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.</p>Formule :C24H16F6N6ODegré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :518.41D-glutamine
CAS :<p>D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.</p>Formule :C5H10N2O3Degré de pureté :99.99%Couleur et forme :White Or Off-White PowderMasse moléculaire :146.14IU1
CAS :<p>IU1 是一种可逆的特异性人类 USP14 蛋白酶体抑制剂，可以穿透细胞，IC50为 4.7 μM。</p>Formule :C18H21FN2ODegré de pureté :98% - 99.3%Couleur et forme :SolidMasse moléculaire :300.37BGT226
CAS :<p>BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.</p>Formule :C28H25F3N6O2Degré de pureté :95.74% - 99.51%Couleur et forme :SolidMasse moléculaire :534.53PF-3845
CAS :<p>PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.</p>Formule :C24H23F3N4O2Degré de pureté :99.54% - 99.58%Couleur et forme :SolidMasse moléculaire :456.46Eprenetapopt
CAS :<p>Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.</p>Formule :C10H17NO3Degré de pureté :98.75% - 99.57%Couleur et forme :SolidMasse moléculaire :199.25ML-SA1
CAS :<p>ML-SA1 (Mucolipin synthetic agonist 1) is a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity.</p>Formule :C22H22N2O3Degré de pureté :99.34% - 99.71%Couleur et forme :SolidMasse moléculaire :362.42VO-Ohpic trihydrate
CAS :<p>VO-Ohpic trihydrate (VO-Ohpic) is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.</p>Formule :C12H9N2O8V·3H2O·HDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :415.2Zoledronic Acid
CAS :<p>Zoledronic Acid (ZOL 446) 是一种含氮二磷酸盐，能抑制破骨细胞的分化和凋亡，具有高效的抗骨质再吸收活性，也有抗癌作用。</p>Formule :C5H10N2O7P2Degré de pureté :98% - 99.93%Couleur et forme :White Crystalline PowderMasse moléculaire :272.09Dynasore
CAS :<p>Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.</p>Formule :C18H14N2O4Degré de pureté :95.85% - 99.22%Couleur et forme :SolidMasse moléculaire :322.31QX77
CAS :<p>QX77 is a chaperone-mediated autophagy (CMA) activator.</p>Formule :C16H13ClN2O2Degré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :300.74NH125
CAS :<p>NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.</p>Formule :C27H45IN2Degré de pureté :98.60%Couleur et forme :SolidMasse moléculaire :524.56Sertindole
CAS :<p>Sertindole, atypical antipsychotic, targets D2, 5-HT1D, 5-HT2A, 5-HT2C receptors (Kds: 2.7, 20, 0.14, 6 nM).</p>Formule :C24H26ClFN4ODegré de pureté :99.87% - 99.92%Couleur et forme :Off-White To Pale Yellow SolidMasse moléculaire :440.94Tanespimycin
CAS :<p>Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!</p>Formule :C31H43N3O8Degré de pureté :99.07% - 99.83%Couleur et forme :Dark Purple SolidMasse moléculaire :585.69STO-609
CAS :<p>STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.</p>Formule :C19H10N2O3Degré de pureté :97.14% - 98.8%Couleur et forme :SolidMasse moléculaire :314.29CX546
CAS :<p>CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also been proposed as a treatment for schizophrenia.</p>Formule :C14H17NO3Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :247.29Cediranib
CAS :<p>Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.</p>Formule :C25H27FN4O3Degré de pureté :97.21% - 99.94%Couleur et forme :SolidMasse moléculaire :450.51Quizartinib
CAS :<p>Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.</p>Formule :C29H32N6O4SDegré de pureté :98% - 99.42%Couleur et forme :SolidMasse moléculaire :560.675-Aminolevulinic acid hydrochloride
CAS :<p>5-Aminolevulinic acid hydrochloride (5-ALA) serves as an intermediate in the body's heme biosynthesis and is the universal precursor of tetrapyrroles.</p>Formule :C5H10ClNO3Degré de pureté :98% - 99.97%Couleur et forme :White To Pale Yellow Crystals OrMasse moléculaire :167.59Ulipristal acetate
CAS :Ulipristal acetate (CDB-2914) is an oral selective progesterone modulator used for emergency contraception and suppressing uterine growths.Formule :C30H37NO4Degré de pureté :98.83% - 99.94%Couleur et forme :SolidMasse moléculaire :475.62Carfilzomib
CAS :<p>Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.</p>Formule :C40H57N5O7Degré de pureté :99.6% - 99.84%Couleur et forme :SolidMasse moléculaire :719.91Nidufexor
CAS :<p>Nidufexor is an agonist for the farnesoid X receptor (FXR).</p>Formule :C27H22ClN3O4Degré de pureté :98.67%Couleur et forme :SolidMasse moléculaire :487.93Berberine
CAS :<p>1.</p>Formule :C20H18NO4Degré de pureté :95.71% - 99.67%Couleur et forme :SolidMasse moléculaire :336.36Isosorbide Mononitrate
CAS :<p>Isosorbide Mononitrate (Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.</p>Formule :C6H9NO6Degré de pureté :98.16%Couleur et forme :Isosorbide-5-Mononitrate Is A Crystalline Solid It Is Very Flammable And May Be Toxic By IngestionMasse moléculaire :191.14UNC0638
CAS :<p>UNC0638 inhibits G9a and GLP lysine methyltransferases with IC50 <15 nM and 19 nM, respectively, showing high selectivity.</p>Formule :C30H47N5O2Degré de pureté :98.88% - 99.53%Couleur et forme :SolidMasse moléculaire :509.73CA-5f
CAS :<p>CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion.</p>Formule :C24H24N2O3Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :388.46Ginkgetin
CAS :<p>Ginkgetin: antiviral, antifungal, anti-inflammatory; COX-2 reducer; STAT3 inhibitor; pro-apoptotic in cancer; neuroprotective in Parkinson's.</p>Formule :C32H22O10Degré de pureté :98.63% - 99.94%Couleur et forme :SolidMasse moléculaire :566.51Rilmenidine Phosphate
CAS :<p>Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.</p>Formule :C10H19N2O5PDegré de pureté :99.87% - ≥95%Couleur et forme :SolidMasse moléculaire :278.24PF-06447475
CAS :<p>PF-06447475 is a highly effective, specific, brain penetrant LRRK2 inhibitor with IC0 of 3/11 nM for wild type LRRK2 and G2019S LRRK2 respectively.</p>Formule :C17H15N5ODegré de pureté :98.61% - 99.62%Couleur et forme :SolidMasse moléculaire :305.33Hesperadin
CAS :<p>Hesperadin(IC50=250 nM) effectively inhibits Aurora B.</p>Formule :C29H32N4O3SDegré de pureté :98.04% - 99.44%Couleur et forme :SolidMasse moléculaire :516.65Metformin
CAS :<p>Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability.</p>Formule :C4H11N5Degré de pureté :99.77% - >99.99%Couleur et forme :SolidMasse moléculaire :129.16Indomethacin farnesil
CAS :<p>Indomethacin farnesil (Infree) is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug.</p>Formule :C34H40ClNO4Degré de pureté :97.29%Couleur et forme :SolidMasse moléculaire :562.14SB 202190
CAS :<p>SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably.</p>Formule :C20H14FN3ODegré de pureté :98% - 99.84%Couleur et forme :Pale YellowMasse moléculaire :331.34CaMKII-IN-1
CAS :<p>CaMKII-IN-1 is a potent and highly selective inhibitor of CaMKII (IC50 = 63 nM).</p>Formule :C29H30ClN5O2SDegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :548.1Dihydromyricetin
CAS :<p>Dihydromyricetin, a flavonoid from Ampelopsis, is an antioxidant that blocks dihydropyrimidinase (IC50: 48 μM) and activates autophagy via mTOR inhibition.</p>Formule :C15H12O8Degré de pureté :96.68% - 98.229%Couleur et forme :SolidMasse moléculaire :320.25MHY1485
CAS :<p>MHY1485 is an mTOR activator that is cell-permeable. MHY1485 inhibits autophagosome and lysosome fusion, thereby inhibiting autophagy. Cost-effective and quality-assured.</p>Formule :C17H21N7O4Degré de pureté :97.74% - >99.99%Couleur et forme :SolidMasse moléculaire :387.39(-)-Epicatechin gallate
CAS :<p>(-)-Epicatechin gallate, a catechin isomer and strong antioxidant, affects membrane proteins and alters gA channel function in bilayers.</p>Formule :C22H18O10Degré de pureté :99.16% - 99.93%Couleur et forme :SolidMasse moléculaire :442.371-Monomyristin
CAS :<p>1-Monomyristin (2,3-Dihydroxypropyl tetradecanoate) , a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterial</p>Formule :C17H34O4Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :302.45Icariin
CAS :<p>Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.</p>Formule :C33H40O15Degré de pureté :97.82% - 98.3%Couleur et forme :SolidMasse moléculaire :676.66Nocodazole
CAS :<p>Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.</p>Formule :C14H11N3O3SDegré de pureté :98% - 99.91%Couleur et forme :Physical Description White Powder (Ntp 1992)Masse moléculaire :301.32CFTR(inh)-172
CAS :<p>CFTR(inh)-172 (CFTR Inhibitor-172) is a voltage-independent, selective CFTR inhibitor.</p>Formule :C18H10F3NO3S2Degré de pureté :98% - 99.72%Couleur et forme :SolidMasse moléculaire :409.4ULK-101
CAS :<p>ULK-101 is a potent and selective ULK1 inhibitor ( IC50s: 8.3/30 nM for ULK1/ULK2). It can suppress autophagy.</p>Formule :C22H16F4N4OSDegré de pureté :97.55% - 99.94%Couleur et forme :SolidMasse moléculaire :460.45Sertaconazole nitrate
CAS :<p>Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.</p>Formule :C20H15Cl3N2OS·HNO3Degré de pureté :98.66% - 99.65%Couleur et forme :SolidMasse moléculaire :500.78Syringin
CAS :<p>Syringin (eleutheroside-b) is a compound with antitumor, antiproliferative, immunomodulatory and platelet aggregation inhibiting effects.</p>Formule :C17H24O9Degré de pureté :98.89% - 99.56%Couleur et forme :SolidMasse moléculaire :372.37PATULIN
CAS :<p>Patulin (Claviform) is a mycotoxin produced by a variety of molds commonly found in rotting apples, including Aspergillus and Penicillium.</p>Formule :C7H6O4Degré de pureté :99.91% - 99.98%Couleur et forme :Compact Prisms Or Thick Plates From Ether Or Chloroform White CrystallineMasse moléculaire :154.12Purmorphamine
CAS :<p>Purmorphamine (Shh Signaling Antagonist VI), which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo.</p>Formule :C31H32N6O2Degré de pureté :97.19% - 99.48%Couleur et forme :Light Tan SolidMasse moléculaire :520.62Regorafenib monohydrate
CAS :<p>Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine</p>Formule :C21H17ClF4N4O4Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :500.83Genipin
CAS :<p>Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis.</p>Formule :C11H14O5Degré de pureté :99.09% - 99.21%Couleur et forme :SolidMasse moléculaire :226.23VER-155008
CAS :<p>VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively.</p>Formule :C25H23Cl2N7O4Degré de pureté :97.03% - 99.55%Couleur et forme :SolidMasse moléculaire :556.4Pitavastatin calcium
CAS :<p>Pitavastatin calcium (NK-104), a inhibitor of HMG-CoA reductase, lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans.</p>Formule :C50H46CaF2N2O8Degré de pureté :98.89% - >99.99%Couleur et forme :White To Off-White PowderMasse moléculaire :880.98Tarenflurbil
CAS :<p>Tarenflurbil, the R-enantiomer of flurbiprofen, lacks COX inhibition and was tested for Alzheimer's treatment.</p>Formule :C15H13FO2Degré de pureté :98% - 99.9%Couleur et forme :SolidMasse moléculaire :244.26Efavirenz
CAS :<p>Efavirenz (DMP 266) is an HIV-1 inhibitor, affecting reverse transcriptase and various cytochrome P450 enzymes.</p>Formule :C14H9ClF3NO2Degré de pureté :99.2% - 99.84%Couleur et forme :White To Slightly Pink Crystalline PowderMasse moléculaire :315.67D4476
CAS :<p>D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).</p>Formule :C23H18N4O3Degré de pureté :99.7% - 99.96%Couleur et forme :SolidMasse moléculaire :398.41Dactolisib
CAS :<p>Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).</p>Formule :C30H23N5ODegré de pureté :97.64% - 99.85%Couleur et forme :SolidMasse moléculaire :469.54Skatole
CAS :<p>Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.</p>Formule :C9H9NDegré de pureté :99.74%Couleur et forme :Leaves From Petroleum Ether; White-Brown Scales SolidMasse moléculaire :131.17MW-150
CAS :<p>MW-150 (MW01-18-150SRM) is a unique protein kinase inhibitor, is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.</p>Formule :C24H23N5Degré de pureté :97.35% - 99.27%Couleur et forme :SolidMasse moléculaire :381.47Lumefantrine
CAS :<p>Lumefantrine, an antimalarial, treats malaria with artemether, effective against Plasmodium spp. including in chloroquine-resistant areas.</p>Formule :C30H32Cl3NODegré de pureté :98.36%Couleur et forme :Yellow SolidMasse moléculaire :528.94Shogaol
CAS :<p>6-Shogaol: anti-inflammatory, analgesic, antipyretic, protects cartilage, arrests cancer cell growth, inhibits metastasis.</p>Formule :C17H24O3Degré de pureté :98.26% - 99.93%Couleur et forme :SolidMasse moléculaire :276.37Dapivirine
CAS :<p>Dapivirine (R147681) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.</p>Formule :C20H19N5Degré de pureté :98% - 99.77%Couleur et forme :SolidMasse moléculaire :329.4PI-103
CAS :<p>PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).</p>Formule :C19H16N4O3Degré de pureté :97.79% - 99.3%Couleur et forme :SolidMasse moléculaire :348.36Tezacaftor
CAS :<p>Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.</p>Formule :C26H27F3N2O6Degré de pureté :98.84% - >99.99%Couleur et forme :SolidMasse moléculaire :520.5NS1643
CAS :<p>NS1643 is a potent human ether-a-go-go related gene (hERG) KV11.1 channel activator with EC50 of 10.5 μM.</p>Formule :C15H10F6N2O3Degré de pureté :98.37% - 99.31%Couleur et forme :SolidMasse moléculaire :380.24Irinotecan
CAS :<p>Irinotecan (CPT-11), a camptothecin derivative, inhibits topoisomerase I, used for colorectal cancer treatment.</p>Formule :C33H38N4O6Degré de pureté :98% - 99.92%Couleur et forme :SolidMasse moléculaire :586.68LY2109761
CAS :<p>LY2109761: a TGF-β dual inhibitor, Ki=38 nM (TβRI) & 300 nM (TβRII), hinders Smad2 phosphorylation.</p>Formule :C26H27N5O2Degré de pureté :97% - 99.83%Couleur et forme :SolidMasse moléculaire :441.52trifarotene
CAS :<p>Trifarotene (CD5789) is a RARγ agonist, 65x more selective than RARα and 16x than RARβ, with EC50 of 7.7 nM.</p>Formule :C29H33NO4Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :459.58Melatonin
CAS :<p>Melatonin (Melatonine) is a natural hormone that activates melatonin receptors. Melatonin regulates the biological clock. Cost-effective and quality-assured.</p>Formule :C13H16N2O2Degré de pureté :98% - 99.89%Couleur et forme :Pale Yellow Leaflets From Benzene SolidMasse moléculaire :232.28Bicyclol
CAS :<p>Bicyclol is an oral anti-hepatitis drug, decreasing ALT/AST levels by 50% and inhibiting HBV/HCV, boosting efficacy with interferon/lamivudine/adefovir.</p>Formule :C19H18O9Degré de pureté :99.64% - 99.85%Couleur et forme :SolidMasse moléculaire :390.34Peiminine
CAS :<p>1. Peiminine (Raddeanine) is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.</p>Formule :C27H43NO3Degré de pureté :99.52% - ≥95%Couleur et forme :White PowderMasse moléculaire :429.64Oprozomib
CAS :<p>Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.</p>Formule :C25H32N4O7SDegré de pureté :98% - 99.87%Couleur et forme :SolidMasse moléculaire :532.61Ridaforolimus
CAS :<p>Ridaforolimus (AP23573) 是亲脂性大环内酯类抗生素雷帕霉素的小分子非前药类似物，具有潜在的抗肿瘤活性。它是一种有效和选择性的 mTOR 抑制剂，在 HT-1080 细胞中抑制 S6 磷酸化的 IC50值为 0.2 nM。</p>Formule :C53H84NO14PDegré de pureté :90.00% - 98.55%Couleur et forme :Off-White SolidMasse moléculaire :990.21Oroxylin A
CAS :<p>Oroxylin A fights tumors, aids RAS therapy, promotes CaCo-2 cell apoptosis, blocks MCF-7 cell invasion and enhances leukemia treatment.</p>Formule :C16H12O5Degré de pureté :98.72% - 99.55%Couleur et forme :SolidMasse moléculaire :284.26SBI-0640756
CAS :<p>SBI-0640756 (SBI-756) (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.</p>Formule :C23H14ClFN2O2Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :404.82Enzalutamide
CAS :<p>Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist (IC50=36 nM in LNCaP).</p>Formule :C21H16F4N4O2SDegré de pureté :99% - 99.93%Couleur et forme :SolidMasse moléculaire :464.44Arctigenin
CAS :<p>(-)-Arctigenin ((-)-Arctigenin) is found in burdock.</p>Formule :C21H24O6Degré de pureté :98% - 99.51%Couleur et forme :SolidMasse moléculaire :372.41PRIMA-1
CAS :<p>PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.</p>Formule :C9H15NO3Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :185.22Fexaramine
CAS :<p>Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity compared to natural compounds.</p>Formule :C32H36N2O3Degré de pureté :98.87% - 99.61%Couleur et forme :SolidMasse moléculaire :496.64GSK2656157
CAS :<p>GSK2656157 is a highly specific and ATP-competitive PERK inhibitor (IC50: 0.9 nM) in a cell-free assay.</p>Formule :C23H21FN6ODegré de pureté :98.59% - >99.99%Couleur et forme :SolidMasse moléculaire :416.45PD-166866
CAS :<p>PD-166866 is a selective FGFR tyrosine kinase inhibitor.</p>Formule :C20H24N6O3Degré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :396.44ICCB-19 hydrochloride
CAS :<p>ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the TRADD-N.</p>Formule :C12H22ClN3OSDegré de pureté :99.3%Couleur et forme :SolidMasse moléculaire :291.84Pictilisib
CAS :<p>Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ).</p>Formule :C23H27N7O3S2Degré de pureté :98.69% - 99.97%Couleur et forme :SolidMasse moléculaire :513.64Sedanolide
CAS :<p>Sedanolide is a natural phthalide first isolated from seed oil of the Umbelliferae family, including celery.</p>Formule :C12H18O2Degré de pureté :≥95% - ≥98%Couleur et forme :SolidMasse moléculaire :194.27(-)-Epigallocatechin
CAS :<p>(-)-Epigallocatechin, the predominant flavonoid in green tea, possesses the unique ability to attach to unfolded native polypeptides, thereby inhibiting their</p>Formule :C15H14O7Degré de pureté :98.83% - >99.99%Couleur et forme :White PowderMasse moléculaire :306.27SF1670
CAS :<p>SF1670 (PTPase CD45 Inhibitor) is a specific PTEN inhibitor with IC50 of 2 μM.</p>Formule :C19H17NO3Degré de pureté :98.25% - 98.54%Couleur et forme :SolidMasse moléculaire :307.34Thiamet G
CAS :<p>Thiamet G is a selective O-GlcNAcase inhibitor (Ki=20 nM). The role of O-GlcNAcase is to remove O-GlcNAc from the modified protein. High-Quality, Low-Cost!</p>Formule :C9H16N2O4SDegré de pureté :99.06% - 99.98%Couleur et forme :SolidMasse moléculaire :248.3Forskolin
CAS :<p>Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).</p>Formule :C22H34O7Degré de pureté :98.83% - 99.96%Couleur et forme :Less Crystalline Solid Colorless Crystalline SolidMasse moléculaire :410.56-Thioguanine
CAS :<p>6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.</p>Formule :C5H5N5SDegré de pureté :98.34% - >99.99%Couleur et forme :Odorless Or Almost Odorless Pale Yellow Crystalline PowderMasse moléculaire :167.19Calcineurin substrate acetate
<p>Calcineurin substrate acetate is from the regulatory RII subunit of cAMP-dependent protein kinase.</p>Formule :C94H154N28O31Degré de pureté :97.59%Couleur et forme :SolidMasse moléculaire :2172.4BIX-01294
CAS :<p>BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).</p>Formule :C28H38N6O2Degré de pureté :98.58% - 99.64%Couleur et forme :SolidMasse moléculaire :490.64PR-619
CAS :<p>PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor. PR-619 induces endoplasmic reticulum stress and activates autophagy. Cost-effective and quality-assured.</p>Formule :C7H5N5S2Degré de pureté :97.25% - >99.99%Couleur et forme :SolidMasse moléculaire :223.28Rosiglitazone
CAS :<p>Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.</p>Formule :C18H19N3O3SDegré de pureté :98.61% - 99.87%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :357.43AZD-3463
CAS :<p>AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.</p>Formule :C24H25ClN6ODegré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :448.95Schisandrin B
CAS :<p>Schisandrin B (Schisandrin B (Sch B)) has an antioxidant effect on rodent liver and heart.</p>Formule :C23H28O6Degré de pureté :99.02% - >99.99%Couleur et forme :SolidMasse moléculaire :400.46(R)-(-)-Gossypol acetic acid
CAS :<p>(R)-(-)-Gossypol acetic acid binds Bcl-2, Bcl-xL, Mcl-1 (Ki: 0.32, 0.48, 0.18 μM); no BIR3/BID inhibition. Phase 2.</p>Formule :C30H30O8·C2H4O2Degré de pureté :98.88% - 99.5%Couleur et forme :SolidMasse moléculaire :578.61Dantrolene sodium hemiheptahydrate
CAS :<p>Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium</p>Formule :C14H9N4NaO5·5H2ODegré de pureté :99.72%Couleur et forme :Orange PowderMasse moléculaire :399.29Tripterin
CAS :<p>Tripterin (Celastrol) is an proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with antioxidant and anti-inflammatory effects.</p>Formule :C29H38O4Degré de pureté :98.56% - 99.8%Couleur et forme :Red Crystalline PowderMasse moléculaire :450.61Mito-LND
CAS :<p>Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.</p>Formule :C43H45BrCl2N3OPDegré de pureté :97.25% - 98.34%Couleur et forme :SolidMasse moléculaire :801.62mTOR inhibitor-1
CAS :<p>C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.</p>Formule :C16H15BrN2O3Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :363.21AT9283
CAS :<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Formule :C19H23N7O2Degré de pureté :99.83% - 99.98%Couleur et forme :SolidMasse moléculaire :381.43Osu03012
CAS :<p>Osu03012 (AR-12): oral celecoxib-derived PDK1 inhibitor with anticancer potential.</p>Formule :C26H19F3N4ODegré de pureté :97.95% - 99.22%Couleur et forme :SolidMasse moléculaire :460.45Afzelin
CAS :<p>Afzelin (Kaempferol-3-O-rhamnoside) has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well as UV-</p>Formule :C21H20O10Degré de pureté :98.92% - 99.38%Couleur et forme :SolidMasse moléculaire :432.38Icaritin
CAS :<p>Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity.</p>Formule :C21H20O6Degré de pureté :97.69% - 99.76%Couleur et forme :SolidMasse moléculaire :368.38Cysteamine hydrochloride
CAS :<p>Cysteamine hydrochloride (Thioethanolamine Hydrochloride) is an agent for the treatment of nephropathic cystinosis and an antioxidant.</p>Formule :C2H7NS·HClDegré de pureté :99.34% - 99.87%Couleur et forme :White Crystalline Powder With A Strong And Disagreeable SmellMasse moléculaire :113.61LY3009120
CAS :<p>LY3009120 (DP-4978) is a potent pan-Raf inhibitor with IC50 of 44 nM, 31-47 nM, and 42 nM for A-raf, B-Raf, and C-Raf in A375 cells, respectively. Phase 1.</p>Formule :C23H29FN6ODegré de pureté :96.96% - ≥95%Couleur et forme :SolidMasse moléculaire :424.51Divalproex Sodium
CAS :<p>Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by</p>Formule :C8H16O2·C8H15O2·NaDegré de pureté :99.87%Couleur et forme :A White Powder With A Characteristic OdorMasse moléculaire :310.41Cilengitide
CAS :<p>Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.</p>Formule :C27H40N8O7Degré de pureté :98% - 99.8%Couleur et forme :SolidMasse moléculaire :588.66Cinobufagin
CAS :<p>Cinobufagin (Cinobufagine) is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.</p>Formule :C26H34O6Degré de pureté :97.77% - 99.97%Couleur et forme :SolidMasse moléculaire :442.54Tamibarotene
CAS :<p>Tamibarotene (Amnolake) is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplastic</p>Formule :C22H25NO3Degré de pureté :98.55% - 99.73%Couleur et forme :Crystalline SolidMasse moléculaire :351.44Chelerythrine
CAS :<p>1.</p>Formule :C21H18NO4Degré de pureté :98.36%Couleur et forme :SolidMasse moléculaire :348.37Fludrocortisone acetate
CAS :<p>Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and</p>Formule :C23H31FO6Degré de pureté :96.92% - 98.03%Couleur et forme :Crystalline SolidMasse moléculaire :422.49Vinblastine sulfate
CAS :<p>Vinblastine sulfate (Vincaleukoblastine sulfate salt) can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM).</p>Formule :C46H58N4O9·H2SO4Degré de pureté :97.81% - 99.68%Couleur et forme :White PowderMasse moléculaire :909.06WYE-354
CAS :<p>WYE-354 is a selective mTOR inhibitor (IC50=5 nM), targeting mTORC1/C2 over PI3Kα (>100x) and PI3Kγ (>500x), sparing P-AKT(T308).</p>Formule :C24H29N7O5Degré de pureté :97.86% - 99.61%Couleur et forme :SolidMasse moléculaire :495.53Tacrolimus
CAS :<p>Tacrolimus (Fujimycin) can bind FKBP12 to form a high-affinity complex (Ki: 0.2 nM) which inhibits the activity of the calcium/calmodulin-dependent protein</p>Formule :C44H69NO12Degré de pureté :98% - 99.94%Couleur et forme :White Or Off-White Crystalline PowderMasse moléculaire :804.02(E)-Daporinad
CAS :<p>(E)-Daporinad (FK866) is a highly specific, non-competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT） .Cost-effective and quality-assured.</p>Formule :C24H29N3O2Degré de pureté :98.44% - >99.99%Couleur et forme :SolidMasse moléculaire :391.51Licochalcone A
CAS :<p>Licochalcone A is a flavonoid isolated from the famous Chinese medicinal herb Glycyrrhiza uralensis Fisch with obvious anti-cancer effects.</p>Formule :C21H22O4Degré de pureté :98.17% - 99.60%Couleur et forme :White Crystalline PowderMasse moléculaire :338.4Brazilin
CAS :<p>1.</p>Formule :C16H14O5Degré de pureté :98% - 99.83%Couleur et forme :SolidMasse moléculaire :286.28N-Benzylpalmitamide
CAS :<p>N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for the</p>Formule :C23H39NODegré de pureté :97.08% - 99.77%Couleur et forme :SolidMasse moléculaire :345.56Parthenolide
CAS :<p>Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB and HDAC1 inhibitor with anti-inflammatory effect. Cost-effective and quality-assured.</p>Formule :C15H20O3Degré de pureté :98.19% - 99.46%Couleur et forme :White To Pale Yellow Crystalline PowderMasse moléculaire :248.328-Chloroadenosine
CAS :<p>8-Chloroadenosine (NSC-354258) is a 5' AMP-activated protein kinase agonist potentially for the treatment of chronic lymphocytic leukemia.</p>Formule :C10H12ClN5O4Degré de pureté :98.75% - 99.84%Couleur et forme :SolidMasse moléculaire :301.69Capivasertib
CAS :<p>Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity.</p>Formule :C21H25ClN6O2Degré de pureté :97.59% - 99.6%Couleur et forme :SolidMasse moléculaire :428.92Dorsomorphin dihydrochloride
CAS :<p>Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on</p>Formule :C24H25N5O·2HClDegré de pureté :97.74% - 99.89%Couleur et forme :SolidMasse moléculaire :472.413PO
CAS :<p>3PO inhibits PFKFB3 (IC50: 22.9 µM) and cancer cell growth (IC50: 1.4-24 µM), reducing glucose uptake and key cellular metabolites.</p>Formule :C13H10N2ODegré de pureté :99.56% - 99.67%Couleur et forme :SolidMasse moléculaire :210.23Corosolic acid
CAS :<p>Corosolic acid inhibits angiogenesis, suppresses FAK, fights various cancers, induces apoptosis, and degrades β-catenin.</p>Formule :C30H48O4Degré de pureté :99.46% - 99.88%Couleur et forme :Fine-Brown Yellow PowderMasse moléculaire :472.7PD168393
CAS :<p>PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.</p>Formule :C17H13BrN4ODegré de pureté :99.13% - 99.83%Couleur et forme :SolidMasse moléculaire :369.22Vemurafenib
CAS :<p>Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and potently.</p>Formule :C23H18ClF2N3O3SDegré de pureté :98% - 99.65%Couleur et forme :SolidMasse moléculaire :489.92Everolimus
CAS :<p>Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.</p>Formule :C53H83NO14Degré de pureté :97.76% - 99.78%Couleur et forme :Off-White To Light Yellow PowdMasse moléculaire :958.22Luminespib
CAS :<p>Luminespib (VER-52296) is an HSP90 inhibitor that inhibits HSP90α and HSP90β. Luminespib has antitumor activity. Cost-effective and quality-assured.</p>Formule :C26H31N3O5Degré de pureté :98% - 99.25%Couleur et forme :SolidMasse moléculaire :465.54Sophocarpine
CAS :<p>Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.</p>Formule :C15H22N2ODegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :246.35Dinoprost tromethamine salt
CAS :<p>Dinoprost tromethamine salt (PGF2α THAM) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.</p>Formule :C24H45NO8Degré de pureté :99.73%Couleur et forme :Natural Form Crystals SolidMasse moléculaire :475.62Idarubicin
CAS :<p>Idarubicin, a potent oral anthracycline, halts DNA/RNA replication and synthesis, damages DNA, and inhibits microbial growth.</p>Formule :C26H27NO9Couleur et forme :SolidMasse moléculaire :497.49
