GPCR/G-Protéine
Les inhibiteurs des GPCR/protéines G sont des composés qui ciblent les récepteurs couplés aux protéines G (GPCR) et les protéines G associées, qui jouent un rôle crucial dans la transmission des signaux de l'extérieur vers l'intérieur des cellules. Ces inhibiteurs sont essentiels pour étudier les voies de signalisation médiées par les GPCR, impliquées dans de nombreux processus physiologiques, y compris la perception sensorielle, la réponse immunitaire et la neurotransmission. Les inhibiteurs des GPCR sont également importants dans le développement de médicaments, car de nombreux agents thérapeutiques ciblent ces récepteurs. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de GPCR/protéines G de haute qualité pour soutenir vos recherches en pharmacologie, biologie cellulaire et domaines connexes.
Sous-catégories appartenant à la catégorie "GPCR/G-Protéine"
- récepteur 5-HT(1.025 produits)
- Récepteur d'adénosine(249 produits)
- Récepteur adrénergique(3.022 produits)
- Récepteur de la bombésine(35 produits)
- Récepteur de la bradykinine(61 produits)
- CXCR(158 produits)
- CaSR(34 produits)
- Récepteur cannabinoïde(217 produits)
- Cholécystokinine(1 produits)
- Récepteur de la dopamine(445 produits)
- Récepteur de l'endothéline(86 produits)
- Récepteur GNRH(84 produits)
- GPCR19(33 produits)
- GRK(33 produits)
- GTPase(23 produits)
- Récepteur du glucagon(194 produits)
- Hérisson/Smoothened(49 produits)
- Récepteur de l'histamine(385 produits)
- Récepteur LPA(21 produits)
- Récepteur de la mélatonine(26 produits)
- Récepteur OX(41 produits)
- Récepteur opioïde(327 produits)
- PAFR(14 produits)
- PKA(60 produits)
- Récepteur S1P(18 produits)
- SGLT(31 produits)
- Récepteur Sigma(46 produits)
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5985 produits trouvés pour "GPCR/G-Protéine"
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17-TFM-PGF1α
CAS :17-TFM-PGF1α (Compound 8) is a saturated prostaglandin analog. It exhibits a high affinity and receptor selectivity for the human prostaglandin F receptor (hFP receptor), with an EC50 of 85 nM.Formule :C24H35F3O5Couleur et forme :SolidMasse moléculaire :460.53B7-33
CAS :B7-33 is a single-chain relaxin analog and a selective agonist for relaxin receptor 1 (RXFP1). It binds to RXFP1 and preferentially activates the pERK pathway in cells expressing RXFP1, rather than cAMP. B7-33 serves as an antifibrotic agent and provides cardioprotective effects.Formule :C131H229N41O36SCouleur et forme :SolidMasse moléculaire :2986.54Protease-Activated Receptor-1, PAR-1 Agonist
CAS :Selective peptide agonist that mimics thrombin to activate PAR-1 receptor, enabling targeted receptor activation.Formule :C35H58N10O9Couleur et forme :SolidMasse moléculaire :762.91Bay 55-9837 TFA
Bay 55-9837 TFA is a VPAC2 agonist with a 0.65 nM Kd, potential for type 2 diabetes research.Formule :C150H240F3ClN44O44Couleur et forme :SolidMasse moléculaire :3456.22Antidepressant agent 4
Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.Formule :C19H38ClN5O2SCouleur et forme :SolidMasse moléculaire :436.06ALD1613
ALD1613 is a potent neutralizing monoclonal antibody targeting adrenocorticotropic hormone (ACTH). It neutralizes ACTH-induced signaling and inhibits cyclic adenosine monophosphate accumulation in ACTH-stimulated Y1 (mouse adrenal cell line) via all five melanocortin receptors. ALD1613 significantly reduces plasma corticosterone levels in wild-type rats and is applicable in studies involving elevated ACTH-related conditions.Couleur et forme :Odour LiquidWB4-24
CAS :WB4-24 is a GLP-1 receptor agonist that enhances the release of β-endorphin in microglia. It exhibits antiallodynic, anti-inflammatory, and analgesic effects in mouse models of inflammation induced by formalin, carrageenan, and CFA.Formule :C52H48N4O14S2Couleur et forme :SolidMasse moléculaire :1017.09[Nle11]-Substance P
CAS :'[Nle11]-Substance P is a gut and brain peptide, resisting methionine oxidation and causing excitatory neural effects.'
Formule :C64H100N18O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1329.59WAY-620645
CAS :WAY-620645 is a CCK antagonist with antitumor and analgesic activities.Formule :C22H22N4O2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :374.44Ref: TM-T9991
1mg38,00€5mg85,00€1mL*10mM (DMSO)104,00€10mg111,00€25mg224,00€50mg318,00€100mg462,00€200mg627,00€8-Chloro caffeine
CAS :8-Chloro caffeine binds to adenosine receptors with a Ki of 30 µM. It enhances UV-induced chromosomal aberrations in the Cl-I type Chinese hamster embryo lung cells. 8-Chloro caffeine is a derivative of the methylxanthine alkaloid caffeine.Formule :C8H9ClN4O2Couleur et forme :SolidMasse moléculaire :228.64Prostaglandin F2α Alcohol
CAS :Prostaglandin F2α Alcohol is a PGF2α (T15133) analogue. Prostaglandin F2α Alcohol is an orally active prostaglandin F receptor (FP receptor) agonist.Formule :C20H36O4Couleur et forme :SolidMasse moléculaire :340.5(Iso)-WAY-260022
CAS :(Iso)-WAY-260022 ((Iso)-NRI-022) is a stereoisomer of WAY-260022, a norepinephrine reuptake inhibitor and selective inhibitor of 5-hydroxytryptamine and dopamine transport proteins.Formule :C21H31F3N2O2Degré de pureté :97.68% - 99.36%Couleur et forme :SoildMasse moléculaire :400.48GEP44
GEP44 is a peptide-biased triple agonist targeting the glucagon-like peptide-1 receptor (GLP-1R), neuropeptide Y1 receptor (Y1-R), and neuropeptide Y2 receptor (Y2-R). It induces GLP-1R-dependent insulin secretion in rat and human islets by offsetting the actions of Y1-R and GLP-1R agonism, controlled by Y1-R antagonists. Additionally, GEP44 enhances glucose uptake in muscle tissue through Y1-R mediation independent of insulin and significantly reduces food intake and body weight in diet-induced obese rat models. GEP44 is utilized in studies related to obesity and type 2 diabetes.Couleur et forme :Odour SolidPG 106 acetate
PG 106 acetate: Selective hMC3 receptor antagonist, IC50=210 nM; inactive on hMC5 and hMC4, EC50=9900 nM.Formule :C53H73N13O11Degré de pureté :98.24%Couleur et forme :SolidMasse moléculaire :1068.23Alkyne-βAG-TOCA
Alkyne-βAG-TOCA is an octreotide derivative that targets somatostatin receptor subtype 2 (SST2). It is utilized in the synthesis and research of radioconjugates (RDC).Formule :C48H65N11O15S2Couleur et forme :SolidMasse moléculaire :1100.22Serazapine
CAS :Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders.
Formule :C22H23N3O2Degré de pureté :98.71% - 99.57%Couleur et forme :SolidMasse moléculaire :361.44Myristoylated ARF6 (2-13)
Myristoylated ARF6 (2-13) inhibits the MyD88–ARNO–ARF6 signaling axis by inactivating ARF6.Formule :C74H128N16O18Masse moléculaire :1528.95925[Ala1,3,11,15]-Endothelin
CAS :Selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ETB and ETA receptors respectively).Formule :C109H163N25O32SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2368GLP-1R/GIPR agonist-1
GLP-1R/GIPR agonist-1 is a dual receptor agonist for GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). It mimics the action of endogenous hormones GLP-1 and GIP, enhancing insulin secretion while suppressing glucagon release, thus lowering blood sugar. This compound is used in research related to metabolic disorders such as diabetes, obesity, and non-alcoholic steatohepatitis (NASH).Formule :C220H342N55O69Masse moléculaire :4858.49434Neocarzinostatin
CAS :Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :N/AFR252384
CAS :FR252384 is an antagonist of the neuropeptide Y-Y5 receptor (IC50: 2.3 nM).Formule :C18H17N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :275.35MR33317
MR33317 is an inhibitor of acetylcholinesterase with an IC50 value of 41 nM. Additionally, it acts as an agonist for brain 5-HT4 receptors.Formule :C22H28ClN3O2Masse moléculaire :401.187Triazolomethylindole-3-acetic acid
CAS :Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.Formule :C13H12N4O2Couleur et forme :SolidMasse moléculaire :256.26Urocortin II, human TFA
hUcn II, a CRF family member, targets CRF2 receptor, has time-linked stress regulation effects, showing mild motor suppression and delayed anxiolytic action.Formule :C196H340F3N63O56SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4564.3KB-5492 FA
KB-5492 FA is a selective sigma receptor inhibitor with antiulcerogenic effects.CAS 번호128-52-56-8Formule :C24H32N2O8Degré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :476.5217-phenyl trinor Prostaglandin F2α methyl amide
CAS :17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor, binding withFormule :C24H35NO4Couleur et forme :SolidMasse moléculaire :401.547Kadsurenin C
CAS :Kadsurenin C (compound 1), a neolignan isolated from the aerial parts of Piper kadsura, exhibits anti-inflammatory properties and significant PAF (Platelet Activating Factor) antagonistic activity, with an IC50 value of 5.1 μM [1].Formule :C21H26O5Masse moléculaire :358.43Upidosin
CAS :Upidosin (SB-216469), a uroselective α1 blocker: Ki α1a=0.34 nM, α1b=3.9 nM, α1d=1.5 nM, α2=33.3 nM.
Formule :C31H33N3O4Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :511.61Binospirone
CAS :Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of movement disorders associated with neurologic dysfunction.Formule :C20H26N2O4Degré de pureté :97.57% - 98.96%Couleur et forme :SoildMasse moléculaire :358.43Ref: TM-T71138L
1mL*10mM (DMSO)33,00€1mg109,00€5mg261,00€10mg374,00€25mg583,00€50mg803,00€100mg1.063,00€200mg1.459,00€Tiaspirone hydrochloride
CAS :Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity and influences the electrophysiological activity of dopaminergic neurons.Formule :C24H33ClN4O2SDegré de pureté :99.87%Couleur et forme :SoildMasse moléculaire :477.06CI-988 hemihydrate
CI-988 hemihydrate (PD134308) is a potent and selective orally active CCK2R (cholecystokinin 2 receptor) antagonist, with an IC50 of 1.7 nM for mouse cortical CCK2. It is over 1600 times more selective for CCK2 than for CCK1 receptors. CI-988 hemihydrate exhibits anxiolytic and antitumor properties.Formule :C35H42N4O6H2OMasse moléculaire :632.321Cholecystokinin (26-33) free acid
CAS :Cholecystokinin (26-33) free acid is part of CCK and induces mild taste aversion conditioning in rats.Formule :C49H61N9O14S2Degré de pureté :99.14%Couleur et forme :SoildMasse moléculaire :1064.19Tetrahydro-β-carboline
CAS :Compound Fr12161, with CAS No. 16502-01-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12161 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C11H12N2Degré de pureté :96.31%Couleur et forme :Tan SolidMasse moléculaire :172.2264Saterinone
CAS :Saterinone: PDE III inhibitor, α-1-adrenoceptor antagonist, vasodilator, used for acute chronic heart failure, IC50 2.3x10^-5 M.Formule :C27H30N4O4Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :474.55Ref: TM-T68138
1mg70,00€5mg152,00€1mL*10mM (DMSO)173,00€10mg222,00€25mg356,00€50mg485,00€100mg648,00€200mg875,00€Adatanserin hydrochloride
CAS :Adatanserin hydrochloride (WY50324 hydrochloride) is a 5-HT(1A)/5-HT(2) receptor ligand that is neuroprotective and may be used in the study of depression.Formule :C21H32ClN5ODegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :405.96Tamsolusin Hydrochloride
CAS :Tamsolusin Hydrochloride (YM 12617) is a highly selective alpha-1A adrenergic receptor antagonist used in the treatment of benign prostatic hypertrophy.Formule :C20H29ClN2O5SDegré de pureté :99.92%Couleur et forme :SoildMasse moléculaire :444.97MrgprX2 antagonist-3
CAS :MrgprX2 antagonist-3 (compound E117) is a MrgprX2 antagonist applicable for investigating cutaneous inflammation.Formule :C16H20FN3O2SDegré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :337.41Ref: TM-T40271
1mg54,00€5mg114,00€1mL*10mM (DMSO)127,00€10mg180,00€25mg362,00€50mg572,00€100mg914,00€Brain Natriuretic Peptide-45, mouse
CAS :Mouse BNP-45, a heart-derived peptide, lowers blood pressure and increases sodium excretion.[Asn18] Endothelin-1, human
CAS :[Asn18] Endothelin-1, human, a peptide, represents a predominant isoform of Endothelin, significantly contributing to the regulation of vascular function [1].Formule :C109H164N26O31S5Masse moléculaire :2494.963D-Monophosphoryl Lipid A-5 triethylamine
3D-Monophosphoryl Lipid A-5 (3D-MPLA-5) triethylamine is a TLR agonist that acts as an adjuvant for vaccines, enhancing their immunogenicity.Formule :C88H170N3O20PMasse moléculaire :1621.27Melanostatin, frog TFA
Melanostatin, frog TFA is an α-MSH release inhibitor, a 36 amino acid peptide isolated from the frog brain.Degré de pureté :99.23%Couleur et forme :Odour SolidBMS-753426
CAS :BMS-753426 is a potent and orally bioavailable antagonist of CCR2 .
Formule :C25H33F3N6O2Couleur et forme :SolidMasse moléculaire :506.574MDL 19301
CAS :MDL 19301 is a nonsteroidal, anti-inflammatory agent.Formule :C15H21NS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :279.46MCL0129
CAS :MCL0129, a selective and non-peptidergic melanocortin 4 (MC4) receptor antagonist, is a potential treatment for cachexia.Formule :C34H47FN4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :546.76Tirzepatide
CAS :Tirzepatide (LY-3298176) is a dual glucose-dependent polypeptide (GIP) (EC50=0.042 nM) and glucagon-like peptide-1 (GLP-1) (EC50=0.086 nM) receptor agonist.Formule :C225H348N48O68Degré de pureté :99.52% - 99.99%Couleur et forme :SolidMasse moléculaire :4813.45Benzquinamide
CAS :Benzquinamide (P2647), an antiemetic agent with anticancer activity, inhibits p-glycoprotein-mediated drug efflux and potentiates the cytotoxicity of anticancerFormule :C22H32N2O5Degré de pureté :94.86%Couleur et forme :SolidMasse moléculaire :404.5KSK94 FA
KSK94 FA is a potent histamine H3 receptor antagonist that inhibits H3 receptors and is used in the study of neuropathic pain and obesity.Formule :C26H28N4O3Degré de pureté :97.51%Couleur et forme :SoildMasse moléculaire :444.53Nα-Methylhistamine FA
Nα-Methylhistamine FA is a histamine H3 receptor agonistFormule :C7H13N3O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :171.2Neurokinin A(4-10) TFA
Neurokinin A (4-10) TFA is a tachykinin NK 2 receptor agonist [1] .Formule :C36H55F3N8O12SCouleur et forme :SolidMasse moléculaire :880.93des-Gln14-Ghrelin TFA
Des-Gln14-Ghrelin TFA, a ligand for GHSR, boosts [Ca2+]i with an EC50 of 2.4 nM in CHO-GHSR62 cells.Formule :C144H238F3N43O42Couleur et forme :SolidMasse moléculaire :3300.69δ8-THC acetate
CAS :Delta8-THC acetate (Delta8-tetrahydrocannabinol) is a psychoactive cannabinoid that binds to the cannabinoid receptor 1 (CB1 receptor) and exhibits anti-nausea, appetite-stimulating, and anti-inflammatory effects. It may also offer neuroprotective benefits and has potential applications in research on anxiety and depression.Formule :C23H32O3Couleur et forme :SolidMasse moléculaire :356.5Asenapine citrate
CAS :Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).Formule :C23H24ClNO8Couleur et forme :SolidMasse moléculaire :477.89Δ9-THCH
CAS :Δ9-THCH, a phytocannabinoid analytical reference standard, is present in a Cannabis variety cultivated for medicinal use. In the United States, it is classified as a Schedule I compound. This product is designated for research and forensic applications.Formule :C22H32O2Couleur et forme :SolidMasse moléculaire :328.49PA-8
CAS :PA-8: Selective PAC1 antagonist, orally active, blocks CREB phosphorylation & cAMP increase (IC50=2nM), reduces pain & aversive response in vivo.Formule :C17H18N4O4Degré de pureté :97.54%Couleur et forme :SolidMasse moléculaire :342.35PACAP (6-38), human, ovine, rat acetate
PACAP (6-38), human, ovine, rat acetate is a potent PACAP receptor antagonist with IC50s of 30, 600, and 40 nM for PACAP type I receptor, PACAP type II receptorFormule :C184H303N55O48SDegré de pureté :99.84%Couleur et forme :SoildMasse moléculaire :4085.84GLP-1 receptor agonist 8
CAS :GLP-1 receptor agonist 8, potent for diabetes and obesity research, may also study NAFLD.Formule :C34H36ClFN6O4Couleur et forme :SolidMasse moléculaire :647.14JNJ-39933673
CAS :JNJ-39933673 is a bio-active chemical.Formule :C48H54F2N2O11Couleur et forme :SolidMasse moléculaire :872.96Secretin (28-54), human TFA
Secretin (28-54), human TFA is a 27-amino acid peptide that works on the human Secretin receptor.Formule :C132H221N44F3O42Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3153.48Substance P(1-7) TFA
CAS :Substance P(1-7) TFA is a fragment of neuropeptide P (SP), with anti-harmful effects, used in neurological disease research.Formule :C43H66F3N13O12Degré de pureté :98.23%Couleur et forme :SolidMasse moléculaire :1014.06Velmupressin acetate
CAS :Potent, selective, short-acting peptidic V2R agonist; EC50: 0.07 nM (hV2R), 0.02 nM (rV2R).Formule :C44H64ClN11O10S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1006.63PG-931 TFA
PG-931 TFA, a potent MC4 receptor agonist (IC50 0.58 nM), excels in selectivity and helps reverse hemorrhagic shock in vivo.Formule :C61H86F3N15O13Couleur et forme :SolidMasse moléculaire :1294.42CH-0076989
CAS :CH-0076989 is a chemokine receptor CCR3 agonist.Formule :C24H22Br2N2O2Couleur et forme :SolidMasse moléculaire :530.25Ribupatide
CAS :Ribupatide is a dual agonist of gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptors and can be utilized in antidiabetic research.Couleur et forme :SolidTAK-448 acetate
CAS :TAK-448 acetate (MVT-602 acetate) is a KISS1R agonist, a synthetic peptide similar to kisspeptin.Formule :C60H84N16O16Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :1285.41Moxonidine hydrochloride
CAS :Moxonidine Hydrochloride: selective I1 imidazoline receptor agonist, stronger than α2-AR; lowers blood pressure; central action.Formule :C9H13Cl2N5OCouleur et forme :SolidMasse moléculaire :278.14Albiglutide Fragment
CAS :Albiglutide fragment is a 30-amino-acid sequence of modified human GLP-1 (fragment 7-36).Formule :C148H224N40O45Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3283.6Bombinakinin M
CAS :Potent, selective bradykinin receptor agonist 50x stronger than bradykinin, contracts guinea pig ileum muscle at EC50 4.0 nM.Formule :C100H159N31O24Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2179.55Fpl 14294
CAS :Fpl 14294 is a novel CCK-8 agonist with effective intranasal anorectic activity in the rat.Formule :C45H56N8O13S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1013.17Adrenotensin (human)
CAS :Adrenotensin: human 153-185 fragment of Adrenomedullin precursor, a 52-amino acid peptide in CGRP hormone family.Formule :C143H224N42O43Couleur et forme :SolidMasse moléculaire :3219.56[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide
CAS :Potent, selective NPY Y5 receptor agonist; IC50: 0.24 nM (Y5), >500 nM (Y2), 530 nM (Y1), 51 nM (Y4); Ki: 0.1-0.15 nM (Y5); increases food intake in vivo.Formule :C183H281N57O54S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4207.67ANXA3 degrader 1
ANXA3 degrader 1 (Compound 18a5) is a highly selective ANXA3 degrader with activity against cancer cells. It demonstrates significant inhibitory effects in a triple-negative breast cancer (TNBC) tumor xenograft model, with a tumor growth inhibition (TGI) rate of 96%.Formule :C30H32N6O2S2Couleur et forme :SolidMasse moléculaire :572.74a-Helical Corticotropin Releasing Factor (9-41)
CAS :α-Helical CRF (9-41) is a CRF antagonist that lowers in vivo plasma GH levels.Formule :C166H273N45O54S2Couleur et forme :SolidMasse moléculaire :3827.34Dapiglutide
CAS :Dapiglutide (ZP7570) is a long-acting GLP-1R & GLP-2R dual agonist for SBS research.Couleur et forme :SolidVU0453379
CAS :VU0453379 is a highly selective and central nervous system penetrant positive allosteric modulator of glucagon-like peptide-1R (EC50: 1.3 μM).Formule :C26H34N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.57ACTH (22-39)
CAS :ACTH (22-39) is an adrenocorticotropic hormone (ACTH) fragment and it is the 22-39 sequence of ACTH.Formule :C90H125N19O32Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1985.06Big endothelin-1 (rat 1-39)
CAS :Big endothelin-1 (rat 1-39), a 39-residue peptide, induces a diuretic and natriuretic response in conscious Sprague-Dawley rats and elevates blood pressure inCouleur et forme :SolidPACAP-38 (31-38), human, mouse, rat acetate
PACAP-38 (31-38) acetate stimulates PAC1 receptor and boosts NPY and catecholamine in sympathetic neurons.Formule :C49H87N17O13Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :1122.32TH023
TH023 is an inhibitor of the TLR4 signaling pathway, specifically targeting the formation of TLR4 homodimers. In HEK-Blue hTLR4 cells, TH023 suppresses the secretion of embryonic alkaline phosphatase with an IC50 of 0.354 μM and inhibits NO expression in RAW264.7 cells, with an IC50 of 1.61 μM. Additionally, TH023 inhibits the activation of NF-κB and reduces the nuclear translocation of NF-κB p65. The compound demonstrates anti-inflammatory effects in a mouse model of LPS-induced acute sepsis and improves lung injury in mice.Formule :C22H21ClF2N4OCouleur et forme :SolidMasse moléculaire :430.88Ceruletide Ammonium Salt
Ceruletide Ammonium Salt is a decapeptide, originating from the skin of tropical frogs, which is a potent cholecystokinin receptor agonist and a safe andFormule :C58H77N14O21S2Degré de pureté :98.47% - 98.54%Couleur et forme :SoildMasse moléculaire :1370.44Ref: TM-T14932L1
1mL*10mM (DMSO)34,00€1mg93,00€5mg313,00€10mg465,00€25mg742,00€50mg982,00€100mg1.333,00€500mg2.637,00€Meclinertant
CAS :Meclinertant: selective NTS1 antagonist, blocks Ca2+ mobilization, with anxiolytic and anti-addictive properties.Formule :C32H31ClN4O5Degré de pureté :97.51% - 99.44%Couleur et forme :SolidMasse moléculaire :587.07Prostaglandin E3
CAS :Prostaglandin E3 (PGE3) is an eicosapentaenoic acid (EPA) derivative with anti-inflammatory and anti-tumor activity, and shows anti-proliferative effects.Formule :C20H30O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :350.45ATMW-2
ATMW-2 is an antagonist engineered using NeuralGenThesis (NGT) technology, specifically targeting the melanocortin 2 receptor (MC2R).Formule :C27H29ClN2O4Couleur et forme :SolidMasse moléculaire :480.98U92016A
CAS :U92016A is a highly potent and selective agonist of 5-HT1A receptor.Formule :C19H25N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :295.42PSB-22269
PSB-22269 is identified as a GPR17 antagonist with a Ki value of 8.91 nM. It exhibits significant inhibitory effects in cAMP and G protein activation assays. Molecular docking studies indicate that the binding site of PSB-22269 includes positively charged arginine residues and a hydrophobic pocket. PSB-22269 promotes myelin regeneration strategies, offering potential for multiple sclerosis research.Formule :C26H21NO6Couleur et forme :SolidMasse moléculaire :443.45Xylamidine
CAS :Xylamidine is a biochemical.Formule :C19H24N2O2Couleur et forme :SolidMasse moléculaire :312.41Xenin-8 TFA
Xenin-8 TFA, a C-terminal octapeptide derived from the 25-amino acid peptide Xenin belonging to the neurotensin/xenopsin family, is biologically active.Setmelanotide Acetate(920014-72-8 free base)
CAS :Setmelanotide Acetate(920014-72-8 free base) (RM-493 Acetate) is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nMFormule :C51H72N18O11S2Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :1177.35Ref: TM-T12882L
1mg124,00€5mg271,00€10mg408,00€1mL*10mM (DMSO)527,00€25mg673,00€50mg945,00€100mg1.279,00€Org 13011
CAS :Org 13011 has CNS activity and induces conditioned taste aversion by mediating 5-HT 1A receptors.Formule :C18H25F3N4ODegré de pureté :98.02%Couleur et forme :SoildMasse moléculaire :370.41Ref: TM-T28258L
1mg109,00€5mg261,00€1mL*10mM (DMSO)266,00€10mg374,00€25mg583,00€50mg803,00€100mg1.063,00€200mg1.431,00€Vensemaglutide
CAS :Vensemaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist, utilized in research related to diabetes or other metabolic disorders.Formule :C214H337N49O67Masse moléculaire :4668.253-Deoxyglucosone
CAS :3-Deoxyglucosone(3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with proteinFormule :C6H10O5Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :162.14Esmolol acid hydrochloride
CAS :Esmolol acid (ASL-8123) hydrochloride is a mild antagonist of β-adrenergic receptors. It inhibits the heart rate and diastolic pressure responses induced by Isoproterenol in a dose-dependent manner and is applicable for renal failure research.Formule :C15H24ClNO4Couleur et forme :SolidMasse moléculaire :317.81Hemokinin 1 (mouse)
CAS :Hemokinin 1 (mouse) is a selective excitogen 1 receptor agonist with a Ki value of 0.175 nM for the human NK1 receptor and 560 nM for the human NK2 receptor.Formule :C61H100N22O15SDegré de pureté :98%Couleur et forme :White PowderMasse moléculaire :1413.6526Rfa, Hypothalamic Peptide, human
CAS :26RFa, a human neuropeptide, stimulates appetite and possibly regulates feeding and the gonadotropic axis, with ≈80% identity across human, rat, and frog.Formule :C127H195N37O37Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2832.13Velmupressin
CAS :Peptidic V2R agonist, c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2, with EC50: 0.07 nM (hV2R), 0.02 nM (rV2R); selective, short-acting.Formule :C42H60ClN11O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :946.58Parstatin(human) TFA
Parstatin(human) TFA, a cell-penetrating PAR-1 thrombin receptor agonist peptide, effectively inhibits angiogenesis, as indicated by studies [1] [2].Formule :C193H331F3N64O55S3Couleur et forme :SolidMasse moléculaire :4581.28RS 56812
CAS :RS 56812 is a 5-HT3 receptor antagonist and agonist used in the study of cognitive disorders.Formule :C18H21N3O2Degré de pureté :99.38%Couleur et forme :SoildMasse moléculaire :311.38Apelin-36(rat, mouse)
CAS :Endogenous APJ agonist from adipocytes; binds APJ tightly, inhibits cAMP, regulates heart function and fluid balance, blocks some HIV strains.Formule :C185H304N68O43SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4200.93Xenin-8
CAS :neurotensin-like peptide that modulate pancreatic insulin and glucagon secretion/effectsFormule :C51H79N15O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1046.275-HT2C agonist-4
CAS :Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.Formule :C24H25N5OCouleur et forme :SolidMasse moléculaire :399.497-Methyl DMT
CAS :7-Methyl DMT (7-TMT) acts as a 5-HT2 receptor agonist. Structurally, it is a tryptamine derivative and serves as an analytical reference for the psychoactive substance DOM. It is also applicable in research related to neurological disorders.Formule :C13H18N2Couleur et forme :SolidMasse moléculaire :202.3
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