GPCR/G-Protéine
Les inhibiteurs des GPCR/protéines G sont des composés qui ciblent les récepteurs couplés aux protéines G (GPCR) et les protéines G associées, qui jouent un rôle crucial dans la transmission des signaux de l'extérieur vers l'intérieur des cellules. Ces inhibiteurs sont essentiels pour étudier les voies de signalisation médiées par les GPCR, impliquées dans de nombreux processus physiologiques, y compris la perception sensorielle, la réponse immunitaire et la neurotransmission. Les inhibiteurs des GPCR sont également importants dans le développement de médicaments, car de nombreux agents thérapeutiques ciblent ces récepteurs. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de GPCR/protéines G de haute qualité pour soutenir vos recherches en pharmacologie, biologie cellulaire et domaines connexes.
Sous-catégories appartenant à la catégorie "GPCR/G-Protéine"
- récepteur 5-HT(1.025 produits)
- Récepteur d'adénosine(251 produits)
- Récepteur adrénergique(3.027 produits)
- Récepteur de la bombésine(35 produits)
- Récepteur de la bradykinine(61 produits)
- CXCR(158 produits)
- CaSR(34 produits)
- Récepteur cannabinoïde(218 produits)
- Cholécystokinine(1 produits)
- Récepteur de la dopamine(445 produits)
- Récepteur de l'endothéline(86 produits)
- Récepteur GNRH(84 produits)
- GPCR19(36 produits)
- GRK(33 produits)
- GTPase(23 produits)
- Récepteur du glucagon(195 produits)
- Hérisson/Smoothened(49 produits)
- Récepteur de l'histamine(385 produits)
- Récepteur LPA(21 produits)
- Récepteur de la mélatonine(26 produits)
- Récepteur OX(41 produits)
- Récepteur opioïde(327 produits)
- PAFR(14 produits)
- PKA(60 produits)
- Récepteur S1P(18 produits)
- SGLT(31 produits)
- Récepteur Sigma(46 produits)
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6011 produits trouvés pour "GPCR/G-Protéine"
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O-2172
CAS :O-2172 is a carbocyclic analogue serving as an inhibitor of dopamine transporter (DAT), exhibiting IC50 values of 47 nM for DAT and 7000 nM for the serotonin transporter (SERT).Formule :C14H16Cl2O2Couleur et forme :SolidMasse moléculaire :287.18Desmethyl Mirtazapine (hydrochloride)
CAS :Desmethyl mirtazapine is a metabolite of the antidepressant mirtazapine.1It is formed from mirtazapine by the cytochrome P450 (CYP) isoform CYP3A4.Formule :C16H18ClN3Couleur et forme :SolidMasse moléculaire :287.79Apigenin 6,8-di-C-α-L-arabinopyranoside
CAS :Apigenin 6,8-di-C-alpha-L-arabinopyranoside is a useful organic compound for research related to life sciences.Formule :C25H26O13Couleur et forme :SolidMasse moléculaire :534.47ent-Prostaglandin E2
CAS :Enzymatic PGE2 is optically pure; radical peroxidation makes it racemic. In oxidative stress, rac-PGE2 forms via 15-E2t-isoprostane.Formule :C20H32O5Couleur et forme :SolidMasse moléculaire :352.47117-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide
CAS :Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.
Formule :C26H36F3NO4Couleur et forme :SolidMasse moléculaire :483.572Nolomirole
CAS :Nolomirole is a dopamine receptor agonist that reduces symptoms of congestive heart failure caused by monoclinine.Formule :C19H27NO4Couleur et forme :SolidMasse moléculaire :333.42GW-328267
CAS :GW-328267 is an agonist of the adenosine A2 receptor.Formule :C21H26N10O4Couleur et forme :SolidMasse moléculaire :482.5Carazolol-d7
CAS :Carazolol-d7 is the deuterium-labeled isotope of Carazolol, commonly used in pharmacokinetic studies to investigate the metabolic pathways of Carazolol.Formule :C18H22N2O2Couleur et forme :SolidMasse moléculaire :305.42CH-0076989
CAS :CH-0076989 is a chemokine receptor CCR3 agonist.Formule :C24H22Br2N2O2Couleur et forme :SolidMasse moléculaire :530.25Formoterol O-β-D-Glucuronide
CAS :Formoterol O-β-D-glucuronide is a metabolite of formoterol .Formule :C25H32N2O10Couleur et forme :SolidMasse moléculaire :520.535(+)-ORM-10921
CAS :(+)-ORM-10921 is a conformation of ORM-10921 and can be used in chemical synthesis studies.Formule :C18H23NO2Degré de pureté :99.23%Couleur et forme :SoildMasse moléculaire :285.38Ularitide
CAS :Ularitide is a 32-amino acid peptide from ANP prohormone, resistant to dog kidney cortex peptidase.Formule :C145H234N52O44S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3505.97GR 82334
CAS :Tachykinin NK1 receptor antagonist.Formule :C69H91N15O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1386.57Physalaemin
CAS :Physalaemin is a non-mammalian tachykinin.Formule :C58H84N14O16SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1265.45SRI-37330
CAS :SRI-37330 inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis.
Formule :C16H19F3N4O2SDegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :388.41Mirtazapine N-oxide
CAS :Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.Formule :C17H19N3OCouleur et forme :SolidMasse moléculaire :281.359Mitemcinal fumarate
CAS :Mitemcinal fumarate is a erythromycin derivative that is used to treat gastroesophageal reflux disease.Formule :C84H142N2O28Couleur et forme :SolidMasse moléculaire :1628.02Neuronostatin-13 (human)
CAS :Neuronostatin-13: human-conserved, 13-amino-acid peptide with amidated C-terminus.Formule :C64H110N20O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1415.681-Octadecyl Lysophosphatidic Acid
CAS :1-Octadecyl LPA, an LPA analog with stearic acid at sn-1, has strong platelet aggregation (EC50=9 nM) via G protein receptors.Formule :C21H45O6PCouleur et forme :SolidMasse moléculaire :424.559Suntinorexton
CAS :Suntinorexton (TAK 861) is an orexin type 2 receptor (OX2R) agonist used in the study of neurologic disorders.Formule :C23H28F2N2O4SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :466.54Ref: TM-T39807
1mg171,00€5mg418,00€1mL*10mM (DMSO)428,00€10mg666,00€25mg1.017,00€50mg1.372,00€100mg1.793,00€200mg2.405,00€Semaglutide, FITC labeled
Semaglutide (FITC-labeled Semaglutide) is a long-acting analog of human glucagon-like peptide-1, functioning as an agonist of the GLP-1 receptor. It shows potential for research related to type 2 diabetes.Formule :C209H304N46O63SMasse moléculaire :4498.17191(Des-Bromo)-Neuropeptide B (1-23) (human)
CAS :'(Des-Bromo)-Neuropeptide B (1-23) (human)' is an agonist for orphan G-protein-coupled receptors, exhibiting a K i of 1.2 nM for GPR7 (NPBW1) and 341 nM forFormule :C107H162N30O30Couleur et forme :SolidMasse moléculaire :2348.61[D-Leu6, Val7]-LH-RH (1-9) Ethyl Amide
[D-Leu6, Val7]-LH-RH (1-9) Ethyl Amide is a LHRH peptide analogue.Formule :C58H82N16O12Couleur et forme :SolidMasse moléculaire :1195.37Acetyl neurotensin (8-13)
CAS :Acetyl neurotensin (8-13), the most concise analog of neurotensin, retains complete binding and pharmacological properties [1].Formule :C40H66N12O9Couleur et forme :SolidMasse moléculaire :859.03KISS1-305
CAS :KISS1-305: Metastin analog, prototype peptide, resists protease degradation, suboptimal KISS1R agonist.Formule :C56H76N16O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1165.3Lintitript
CAS :Lintitript (SR 27897) is a selective antagonist of CCK1 with EC50s of 6 nM and 200 nM for CCK1 and CCK2. The Ki value is 0.2 nM for CCK1.Formule :C20H14ClN3O3SDegré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :411.86Ref: TM-T15759
1mg50,00€2mg71,00€5mg105,00€1mL*10mM (DMSO)117,00€10mg160,00€25mg344,00€50mg645,00€100mg864,00€CTP-amiodarone
CTP-amiodarone, a cellular-penetrating conjugate of myocardial cell-targeting peptide and Amiodarone, exhibits anti-arrhythmic activity by blocking Na+, K+, and Ca2+ channels as well as β-adrenergic receptors.Formule :C97H131F3I2N20O25S2Couleur et forme :SolidMasse moléculaire :2352.13LY-426965 hydrochloride
CAS :LY-426965 hydrochloride is a bioactive chemical.Formule :C28H39ClN2O2Couleur et forme :SolidMasse moléculaire :471.07PAMP-12(human, porcine)
CAS :Potent endogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC50 = 57.2 nM). Corresponds to amino acids 9 to 20 of proadrenomedullin.Formule :C77H119N25O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1618.95Crustacean Cardioactive Peptide (CCAP)
CAS :Crustacean Cardioactive Peptide (CCAP) is a conserved modified cyclic nonapeptide primary structure of PFCNAFTGC-NH2, a disulfide bridge between Cys3 and Cys9.Formule :C42H58N10O12S2Degré de pureté :95.40%Couleur et forme :SolidMasse moléculaire :959.1Ornipressin
CAS :Ornipressin is a vasoconstrictor, haemostatic and renal agent.Formule :C45H63N13O12S2Degré de pureté :98%Couleur et forme :White PowderMasse moléculaire :1042.195-HT6R antagonist 6
5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.Formule :C24H26N4O2SCouleur et forme :SolidMasse moléculaire :434.55BE-24566B
CAS :BE-24566B, a polyketide from S. violaceusniger, inhibits various bacteria and blocks ET receptors (ETA IC50=11 μM, ETB=3.9 μM).Formule :C27H24O7Couleur et forme :SolidMasse moléculaire :460.4823-hydroxy Desloratidine
CAS :3-hydroxy Desloratidine is a major metabolite of desloratadine , a tricyclic antagonist of the histamine H1 receptor.Formule :C19H19ClN2OCouleur et forme :SolidMasse moléculaire :326.82Glucagon Receptor Antagonist Inactive Control
CAS :Glucagon Receptor Antagonist Inactive Control is a Glucagon receptor antagonist that can be used in related research in the field of life sciences.Formule :C21H23BrN2OSCouleur et forme :SolidMasse moléculaire :431.39Astressin
CAS :Astressin is a truncated CRF analog; binds strongly to receptor's extracellular domain, likely acting as a neutral competitive antagonist.Formule :C161H269N49O42Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3563.16Cannabigerorcinic Acid
CAS :Cannabigerorcinic acid, structurally akin to recognized phytocannabinoids, serves as an analytical reference standard designed for research and forensic purposes.Formule :C18H24O4Couleur et forme :SolidMasse moléculaire :304.386HTR2A antagonist 1
HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.Formule :C35H43Cl2F2N5O4Couleur et forme :SolidMasse moléculaire :706.65mPGES-1/sEH-IN-1
mPGES-1/sEH-IN-1 (compound 1f) is an sEH inhibitor with an IC50 value of 5 μM. It also exhibits antitumor activity by inhibiting mPGES-1, with an IC50 value of 25 µM.Formule :C20H16F3N3O2Couleur et forme :SolidMasse moléculaire :387.355Prostaglandin F2α 1,11-lactone
CAS :Prostaglandin F2α 1,11-lactone (PGF2α 1,11-lactone) is a lipid-soluble prodrug of Prostaglandin F2α and can be used in studies about treating glaucoma.Formule :C20H32O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :336.47U92016A
CAS :U92016A is a highly potent and selective agonist of 5-HT1A receptor.Formule :C19H25N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :295.428-iso Prostaglandin E2 isopropyl ester
CAS :8-iso PGE2 isopropyl ester: lipophilic, hydrolyzes to acid in vivo, used as prodrug, less active than parent acid.Formule :C23H38O5Couleur et forme :SolidMasse moléculaire :394.54NN1213
NN1213 (Peptide 21) is a long-acting human amylin peptide analogue that functions as a selective amylin receptor agonist. It has an EC50 of 0.177 nM for hAMY3R and 0.262 nM for rAMY3R. In both rat and dog models, NN1213 significantly reduces appetite and is utilized in anti-obesity research.Couleur et forme :Odour SolidYM 218
CAS :YM 218 is a novel, potent, selective antagonist of nonpeptide vasopressin V1A receptor.Formule :C35H38F2N4O4Couleur et forme :SolidMasse moléculaire :616.7Urocortin II, human acetate
Urocortin II, human acetate, is a selective endogenous peptide agonist of type 2 corticotropin-releasing factor (CRF2) receptors, used to study the role of CRF2 receptors in feeding behavior.Couleur et forme :Odour SolidCannabinol methyl ether
CAS :Cannabinol methyl ether, a phytocannabinoid, serves as an analytical reference standard. This compound can be obtained through isolation from Cannabis plants, derived from cannabinol, or synthesized. The physiological and toxicological properties of cannabinol methyl ether remain unknown. It is designed exclusively for research and forensic applications.Formule :C22H28O2Couleur et forme :SolidMasse moléculaire :324.5Prostaglandin F2α methyl ester
CAS :Prostaglandin F2α methyl ester is a highly lipid-soluble PGF2α analog used to maintain low intraocular pressure.Formule :C21H36O5Couleur et forme :SolidMasse moléculaire :368.51(−)-6α-hydroxy Cannabidiol
CAS :(−)-6α-Hydroxy Cannabidiol, an analytical reference standard and a phytocannabinoid metabolite, serves primarily as a metabolite of cannabidiol (CBD). This product is designed for use in research and forensic applications.Formule :C21H30O3Couleur et forme :SolidMasse moléculaire :330.46HGS101
HGS101 is a fully humanized CCR5 monoclonal antibody that exhibits high affinity for CCR5. It binds to the second extracellular loop (ECL-2) and functions as a signaling antagonist. HGS101 restores the inhibitory effect of Maraviroc in Maraviroc-resistant HIV-1 infected PBMCs. In an uninfected simian immunodeficiency virus model of rhesus monkeys, HGS101 shows anti-HIV activity by inhibiting CCR5 signaling.Couleur et forme :Odour LiquidCCK (26-31) (non-sulfated)
CAS :CCK (26-31) is a digestive, satiety-inducing, anxiety-related peptide fragment from CCK hormone in the brain and gut.Formule :C38H50N8O10S2Couleur et forme :SolidMasse moléculaire :842.98Endothelin-2 (49-69), human TFA
Endothelin-2 (49-69), human (TFA) is a 21-amino acid vasoactive peptide that binds to ET-RA and ET-RB.Formule :C117H161N26F3O34S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2660.94Lenbelintide
CAS :Lenbelintide is a dual amylin/calcitonin receptor agonist, useful in studies related to obesity.Couleur et forme :SolidBerobenatide
CAS :Berobenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist.Couleur et forme :SolidGEP44
GEP44 is a peptide-biased triple agonist targeting the glucagon-like peptide-1 receptor (GLP-1R), neuropeptide Y1 receptor (Y1-R), and neuropeptide Y2 receptor (Y2-R). It induces GLP-1R-dependent insulin secretion in rat and human islets by offsetting the actions of Y1-R and GLP-1R agonism, controlled by Y1-R antagonists. Additionally, GEP44 enhances glucose uptake in muscle tissue through Y1-R mediation independent of insulin and significantly reduces food intake and body weight in diet-induced obese rat models. GEP44 is utilized in studies related to obesity and type 2 diabetes.Couleur et forme :Odour SolidJMV3008
CAS :JMV3008 is a bioactive chemical.Formule :C36H39N7O3Couleur et forme :SolidMasse moléculaire :617.74VIP(Guinea pig)
CAS :Neuropeptide with many biological actionsFormule :C147H239N43O42S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3344.86Add 4743
CAS :Add 4743 is an analog of sitoglitazone, which is also a fat-forming agent.Formule :C18H23NO4SCouleur et forme :SolidMasse moléculaire :349.44PAF C-16 Carboxylic Acid
CAS :PAF C-16, a natural phospholipid, triggers neutrophil migration, ROS, IL-6 production, and is linked to necrotizing enterocolitis.Formule :C26H52NO9PCouleur et forme :SolidMasse moléculaire :553.67Somatostatin-25
CAS :Somatostatin: a brain/pancreas hormone binding receptors, with anxiolytic, antiepileptic, and appetite-suppressing effects.Formule :C127H191N37O34S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2876.3LM11A-31
CAS :LM11A-31 is a useful organic compound for research related to life sciences. The catalog number is T35365 and the CAS number is 289475-77-0.Formule :C12H25N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :243.351PAMP-12(human, porcine) TFA
PAMP-12(human, porcine) TFA, a significant constituent of immunoreactive (ir)-PAMP, derives from the adrenomedullin precursor and functions as a potentCouleur et forme :Odour SolidNeuropeptide W-23 (human) (TFA)
Neuropeptide W-23 (human) (NPW-23) TFA, representing the active form of Neuropeptide W, functions as an endogenous agonist for both NPBW1 (GPR7) and NPBW2 (GPR8Couleur et forme :Odour SolidAP 811
CAS :AP 811: Selective NPR3 antagonist, Ki of 0.48 nM, >20,000x selective over NPR1, blocks ANP-induced pump stimulation.Formule :C46H66N12O8Couleur et forme :SolidMasse moléculaire :915.11Contulakin G
CAS :Contulakin G: O-glycosylated neurotensin, weak neurotensin receptor agonist, strong antinociceptive.Formule :C88H140N20O37Masse moléculaire :2070.1715(S)-Latanoprost
CAS :15(S)-Latanoprost, a latanoprost analog with inverted hydroxyl at C-15, has an IC50 of 24 nM and reduces IOP by 1 mmHg at 3 μg.Formule :C26H40O5Couleur et forme :SolidMasse moléculaire :432.59Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP (1-7)-GRF (8-27)
CAS :Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP(1-7)-GRF(8-27) is a selective antagonist [1] for the vasoactive intestinal peptide 1 (VIP 1) receptor.Formule :C150H246N44O38Couleur et forme :SolidMasse moléculaire :3273.83[D-Phe2,6, Pro3]-LH-RH
CAS :[D-Phe2,6, Pro3]-LH-RH is a potent antagonist of luteinizing hormone-releasing hormone (LHRH).Formule :C59H80N14O13Couleur et forme :SolidMasse moléculaire :1193.35(Leu31,Pro34)-Peptide YY (human)
CAS :(Leu31,Pro34)-Peptide YY (human) is a derivative of Peptide YY, acting as a potent and selective Y1 receptor agonist with a dissociation constant (KD) of 1.0 nMFormule :C195H296N54O56Couleur et forme :SolidMasse moléculaire :4292.75CCK (27-33) (non-sulfated)
CAS :CCK (27-33), a non-sulfated peptide, inhibits [3H]naloxone binding (IC50=4uM) and guinea pig ileum contractions (IC50=17uM), reversed by naloxone.Formule :C45H57N9O10S2Couleur et forme :SolidMasse moléculaire :948.12Oxopurpureine
CAS :Oxopurpureine, classified as an oxoaporphine compound, functions to inhibit plant pathogens.Formule :C21H19NO6Couleur et forme :SolidMasse moléculaire :381.38ent-8-iso Prostaglandin F2α
CAS :ent-8-iso Prostaglandin F2α is a potent vasoconstrictor of porcine retinal and cerebral microvessels with EC50 values of 30.6 and 53.5 nM, respectively.Formule :C20H34O5Couleur et forme :SolidMasse moléculaire :354.487Gastrin I (1-14), human TFA
Gastrin I (1-14), human TFA is 1-14 fragment of human gastrin I peptide.Formule :C81H101N16F3O29Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1819.75Neurokinin A TFA
CAS :Neurokinin A TFA (NKA TFA) is a neuropeptide within the neurokinin family, serving as the endogenous ligand and agonist for the NK-2 (Neurokinin 2) receptor.Formule :C52H81F3N14O16SDegré de pureté :98.704%Couleur et forme :SolidMasse moléculaire :1247.34(D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide
CAS :Somatostatin analog (Compound 4) with Kd: SSTR5-0.61nM, SSTR3-11.05nM, SSTR2-23.5nM, SSTR1-1.2µM, SSTR4->1µM.Formule :C50H67N11O10S2Masse moléculaire :1046.26Methylsolfonyl 25(S)-Δ7-dafachronic acid
Methylsulfonyl 25(S)-Δ7-dafachronic acid (compound 3) is a selective ssDAF-12 agonist with an IC50 value of 0.41 μM. It exhibits low cytotoxicity in HepG2 cells, with an IC50 value greater than 200 μM. Methylsulfonyl 25(S)-Δ7-dafachronic acid is applicable in the study of parasitic diseases.Formule :C28H45NO4SMasse moléculaire :491.30693Olanzapine Lactam Impurity
CAS :Olanzapine lactam impurity, found in olanzapine, forms under heat or oxidative stress.Formule :C17H20N4O2Couleur et forme :SolidMasse moléculaire :312.373Prostaglandin E2 isopropyl ester
CAS :PGE2 isopropyl ester, a lipophilic prodrug of PGE2, gains solubility in lipids and activates upon in vivo hydrolysis.Formule :C23H38O5Couleur et forme :SolidMasse moléculaire :394.552Cyclo(L-Leu-L-Trp)
CAS :Cyclo(L-Leu-L-Trp) is a diketopiperazine metabolite initially derived from Penicillium, exhibiting antibacterial (MICs = 125-1000 µg/ml) and antifungal activities (MICs = 8-64 µg/ml). It also demonstrates antioxidant properties by reducing the production of hydroxy radicals, as evidenced in an electron spin resonance (ESR) spectroscopy assay (IC50 = 1.8 µM). Additionally, Cyclo(L-Leu-L-Trp) has been identified as a bitter compound capable of quickly crossing rat taste cell membranes ex vivo at a 1 mM concentration. Furthermore, it acts as a melatonin receptor agonist in X. laevis melanophores, suppressing cAMP accumulation at a 20 µM concentration, with this effect being negated by the melatonin receptor antagonist luzindole.Formule :C17H21N3O2Couleur et forme :SolidMasse moléculaire :299.374A 70874
CAS :A70874 has high selectivity and potency for cholecystokinin (CCK) a receptor.Formule :C45H55N7O10Couleur et forme :SolidMasse moléculaire :853.974PT-129
PT-129 is a PROTAC degrader targeting the NTF2 domain of G3BP1/2, degrading stress granules in stressed cells, suppressing proliferation.Formule :C46H48N8O12SCouleur et forme :SolidMasse moléculaire :936.98Idazoxan
CAS :Idazoxan is an alpha2 receptor antagonist that also exhibits activity at imidazoline [I1] and [I2] receptors, playing a role in modulating dopamine release.Formule :C11H12N2O2Masse moléculaire :204.23GLP-1R agonist 26
CAS :Compound 1, also known as GLP-1R agonist 26, is an agonist of the glucagon-like peptide-1 receptor (GLP-1R) with an EC50 of <10 nM.Formule :C32H29FN6O4SCouleur et forme :SolidMasse moléculaire :612.67pCPA methyl ester hydrochloride
CAS :pCPA methyl ester HCl inhibits tryptophan hydroxylase, 5-HT synthesis, crosses blood-brain barrier, lowers central 5-HT.
Formule :C10H13Cl2NO2Degré de pureté :99.73% - 99.88%Couleur et forme :SolidMasse moléculaire :250.12Ribupatide
CAS :Ribupatide is a dual agonist of gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptors and can be utilized in antidiabetic research.Couleur et forme :Solid(Iso)-Samixogrel
CAS :(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.Formule :C25H25ClN2O4SDegré de pureté :98.85%Couleur et forme :SolidMasse moléculaire :484.99[Asn18] Endothelin-1, human
CAS :[Asn18] Endothelin-1, human, a peptide, represents a predominant isoform of Endothelin, significantly contributing to the regulation of vascular function [1].Formule :C109H164N26O31S5Masse moléculaire :2494.96TH023
TH023 is an inhibitor of the TLR4 signaling pathway, specifically targeting the formation of TLR4 homodimers. In HEK-Blue hTLR4 cells, TH023 suppresses the secretion of embryonic alkaline phosphatase with an IC50 of 0.354 μM and inhibits NO expression in RAW264.7 cells, with an IC50 of 1.61 μM. Additionally, TH023 inhibits the activation of NF-κB and reduces the nuclear translocation of NF-κB p65. The compound demonstrates anti-inflammatory effects in a mouse model of LPS-induced acute sepsis and improves lung injury in mice.Formule :C22H21ClF2N4OCouleur et forme :SolidMasse moléculaire :430.88Wy 41747
CAS :Wy 41747 is a long-acting somatostatin analogue utilized in research of diabetes mellitus [1].Formule :C73H92N18O16S2Masse moléculaire :1541.75Velmupressin
CAS :Peptidic V2R agonist, c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2, with EC50: 0.07 nM (hV2R), 0.02 nM (rV2R); selective, short-acting.Formule :C42H60ClN11O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :946.58Xenin-8
CAS :neurotensin-like peptide that modulate pancreatic insulin and glucagon secretion/effectsFormule :C51H79N15O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1046.27[Lys8] Vasopressin Desglycinamide
CAS :[Lys8] Vasopressin Desglycinamide, a vasopressin analog, supports the maintenance of active and passive avoidance behavior and aids in the facilitation ofFormule :C44H63N11O12S2Couleur et forme :SolidMasse moléculaire :1002.17P2Y1 antagonist 3
P2Y1 antagonist 3 (compound 36b) is a P2Y1 antagonist capable of penetrating the blood-brain barrier (BBB), with an IC50 value of 0.50 μM. In a rat middle cerebral artery occlusion (MCAO) model, it demonstrates protective properties and exhibits neuroprotective effects against oxidative stress by upregulating Nrf2 protein levels.Couleur et forme :Odour SolidFemoxetine
CAS :Femoxetine: antidepressant, enhances morphine, inhibits MAO-A/B, boosts mice's exercise capacity.Formule :C20H25NO2Degré de pureté :99.1% - 99.35%Couleur et forme :SolidMasse moléculaire :311.42Tagmokitug
CAS :Tagmokitug is a humanized IgG1κ monoclonal antibody inhibitor targeting CCR8. It exhibits anti-tumor activity and is applicable in cancer immunotherapy research, including studies on breast cancer, colon cancer, and lung cancer.Maridebart
CAS :Maridebart is a humanized IgG1-kappa monoclonal antibody that targets the GIPR (gastric inhibitory polypeptide receptor) [1].Couleur et forme :Liquid(±)14(15)-EpETE
CAS :(±)14(15)-EpETE is an intestinal microbial lipid metabolite that attenuates cisplatin chemotherapy-induced nausea in rats by inhibiting Substance P release.Formule :C20H30O3Couleur et forme :SolidMasse moléculaire :318.45SAG dihydrochloride
CAS :SAG dihydrochloride: potent Smo agonist, activates Hedgehog pathway, counters Cyclopamine. EC50=3 nM, Kd=59 nM.Formule :C28H30Cl3N3OSDegré de pureté :99.57%Couleur et forme :SoildMasse moléculaire :562.98Nizatidine
CAS :Nizatidine (Acinon) is a competitive and reversible histamine H2-receptor antagonist with antacid activity.Formule :C12H21N5O2S2Degré de pureté :98.39% - 99.43%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :331.46AG 045572
CAS :AG 045572 is a potent GnRH receptor antagonist that inhibits the GnRH receptor in humans and rats with Ki values of 6.0 nM and 3.8 nM, respectively.AG 045572 isFormule :C30H37NO5Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :491.62GLP-1(28-36)amide acetate
GLP-1(28-36)amide acetate inhibits mitochondrial permeability transition with antioxidant, anti-diabetic and cardioprotection activities.Formule :C56H89N15O11Degré de pureté :99.9500%Couleur et forme :SolidMasse moléculaire :1148.4Ref: TM-T37890L
1mL*10mM (DMSO)À demander1mg127,00€5mg249,00€10mg419,00€25mg692,00€50mg938,00€100mg1.320,00€500mg2.642,00€
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