GPCR/G-Protéine
Les inhibiteurs des GPCR/protéines G sont des composés qui ciblent les récepteurs couplés aux protéines G (GPCR) et les protéines G associées, qui jouent un rôle crucial dans la transmission des signaux de l'extérieur vers l'intérieur des cellules. Ces inhibiteurs sont essentiels pour étudier les voies de signalisation médiées par les GPCR, impliquées dans de nombreux processus physiologiques, y compris la perception sensorielle, la réponse immunitaire et la neurotransmission. Les inhibiteurs des GPCR sont également importants dans le développement de médicaments, car de nombreux agents thérapeutiques ciblent ces récepteurs. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de GPCR/protéines G de haute qualité pour soutenir vos recherches en pharmacologie, biologie cellulaire et domaines connexes.
Sous-catégories appartenant à la catégorie "GPCR/G-Protéine"
- récepteur 5-HT(1.025 produits)
- Récepteur d'adénosine(251 produits)
- Récepteur adrénergique(3.025 produits)
- Récepteur de la bombésine(35 produits)
- Récepteur de la bradykinine(61 produits)
- CXCR(158 produits)
- CaSR(34 produits)
- Récepteur cannabinoïde(218 produits)
- Cholécystokinine(1 produits)
- Récepteur de la dopamine(445 produits)
- Récepteur de l'endothéline(86 produits)
- Récepteur GNRH(84 produits)
- GPCR19(36 produits)
- GRK(33 produits)
- GTPase(23 produits)
- Récepteur du glucagon(195 produits)
- Hérisson/Smoothened(49 produits)
- Récepteur de l'histamine(385 produits)
- Récepteur LPA(21 produits)
- Récepteur de la mélatonine(26 produits)
- Récepteur OX(41 produits)
- Récepteur opioïde(327 produits)
- PAFR(14 produits)
- PKA(60 produits)
- Récepteur S1P(18 produits)
- SGLT(31 produits)
- Récepteur Sigma(46 produits)
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6011 produits trouvés pour "GPCR/G-Protéine"
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2-Arachidonoylglycerol-d5
CAS :2-Arachidonoylglycerol-d5 is the deuterated form of 2-Arachidonoylglycerol, which acts as an endogenous cannabinoid ligand within the central nervous system.Formule :C23H38O4Couleur et forme :SolidMasse moléculaire :383.58Deoxycholic acid-d5
CAS :Deoxycholic acid-d5 is the deuterated form of Deoxycholic acid. It activates the G protein-coupled bile acid receptor TGR5.Formule :C24H40O4Couleur et forme :SolidMasse moléculaire :397.60Harmane-d
Harmane-d is the deuterated form of Harmane. Harmane, a β-carboline alkaloid (BCA), acts as a potent neurotoxin, inducing marked tremors and psychiatric symptoms. It exhibits a high affinity for the I1 imidazoline receptor (IC50=30 nM), showing 1000 times more selectivity than for the α2-adrenergic receptor (IC50=18 μM). Additionally, Harmane is an efficient and selective monoamine oxidase inhibitor, with IC50 values of 0.5 μM and 5 μM for MAO A and B, respectively.Couleur et forme :Odour SolidUrsodeoxycholic acid-d5
CAS :Ursodeoxycholic acid-d5 is the deuterated form of Ursodeoxycholic acid. Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid produced through the transformation of (cheno)deoxycholic acid by intestinal bacteria. It plays a crucial role in maintaining intestinal barrier integrity and is essential for lipid metabolism. As a signaling molecule, Ursodeoxycholic acid functions by interacting with bile acid-activated receptors, including the G protein-coupled bile acid receptor 5 (TGR5, GPCR19) and the Farnesoid X receptor (FXR). It is used in research related to various liver and gastrointestinal disorders and is effective when administered orally.Formule :C24H40O4Couleur et forme :SolidMasse moléculaire :397.60Liraglutide-13C5,15N TFA
Liraglutide-13C5,15N (tetraTFA) is a version of Liraglutide labeled with 13C and 15N isotopes. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist, which is clinically used for the treatment of type 2 diabetes.Couleur et forme :Odour SolidAdrenocorticotropic Hormone (ACTH) (4-10), human
CAS :Adrenocorticotropic Hormone (ACTH) (4-10) is an agonist of potent melanocortin(MC4R) receptor .Formule :C44H59N13O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :962.093F6-9G5
3F6-9G5 is a humanized monoclonal antibody targeting AA2AR/Adenosine A2aR, used in neurodegenerative disease research.Degré de pureté :>95%Couleur et forme :Odour LiquidMasse moléculaire :146.66 kDaIRL-1038 TFA
IRL-1038 TFA is an ETB receptor antagonist used in the study of cardiovascular disease.Formule :C70H93F3N14O17S2Degré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :1523.7N-Desmethyl Pimavanserin
CAS :N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.Formule :C24H32FN3O2Degré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :413.53W140 HBr
CAS :[(3S)-3-amino-4-(3-hexylanilino)-4-oxobutyl]phosphonic acid;hydrobromide is a S1P1 antagonist with Ki of 2.84 μM.Formule :C16H28BrN2O4PDegré de pureté :99.85%Couleur et forme :SoildMasse moléculaire :423.28Ref: TM-T60204
1mg115,00€2mg172,00€5mg255,00€1mL*10mM (DMSO)284,00€10mg375,00€25mg562,00€50mg787,00€100mg1.074,00€L 152804
CAS :L 152804: Y5 receptor antagonist, reduces food intake/boosts energy, leads to weight loss in obese mice.Formule :C23H26O4Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :366.45Ref: TM-T15679
5mg48,00€1mL*10mM (DMSO)49,00€10mg75,00€25mg111,00€50mg170,00€100mg245,00€200mg349,00€Noladin ether
CAS :Noladin ether (2-AG ether) is a cannabinoid CB1 receptor agonist.Formule :C23H40O3Couleur et forme :SolidMasse moléculaire :364.56BMY-14802
CAS :BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.Formule :C18H22F2N4ODegré de pureté :99.84%Couleur et forme :SoildMasse moléculaire :348.39Ref: TM-T67739
2mg35,00€5mg52,00€1mL*10mM (DMSO)58,00€10mg90,00€25mg164,00€50mg259,00€100mg383,00€200mg545,00€MD01-67
CAS :MD01-67 is a macrocyclic compound selectively targeting the neurotensin 2 receptor (NTS2), with a Ki of 2.9 nM. It exhibits analgesic activity and reduces tactile hypersensitivity in rat models of acute, sustained, and chronic inflammatory pain.Formule :C37H58N8O8Couleur et forme :SolidMasse moléculaire :742.91EB1002
CAS :EB1002 is a selective NK2R agonist that has demonstrated significant enhancements in the expression levels of genes associated with mitochondrial biogenesis (such as PGC-1α) in obese mice. This suggests that EB1002 promotes energy expenditure by enhancing mitochondrial activity. Additionally, EB1002 has improved insulin sensitivity and glucose-lipid metabolism in mice. Therefore, EB1002 holds potential for research into obesity and type 2 diabetes.Formule :C73H124N12O23Couleur et forme :SolidMasse moléculaire :1537.83γ-Glu-Abu TFA
Gamma-Glu-AbuTFA is the TFA salt form of Gamma-Glu-Abu. This compound acts as an agonist for the calcium sensing receptor (CaSR), activating CaSR in HEK-293 cells with an EC50 of 0.21 μM.Formule :C11H17F3N2O7Couleur et forme :SolidMasse moléculaire :346.26Calcitonin-13C6,15N4 TFA
Calcitonin-13CIC6,15NIC4(salmon) (Salmon calcitonin-13CIC6,15NIC4) TFA is a version of calcitonin(salmon) labeled with carbon-13 and nitrogen-15. This hormone regulates calcium and acts dualistically as an agonist to both amylin and calcitonin receptors, promoting bone formation while inhibiting bone resorption.Formule :C1401C5H240N4315NO48S2·5C2HF3O2Couleur et forme :SolidMasse moléculaire :4007.93Boc-Phe-Leu-Phe-Leu-Phe
CAS :Boc-Phe-Leu-Phe-Leu-Phe is a chemotactic peptide antagonist that inhibits the release of peptide leukotrienes induced by FMLP.Formule :C44H59N5O8Couleur et forme :SolidMasse moléculaire :785.975-HT1AR agonist 2
5-HT1AR Agonist 2 (Compound 4f) is a potent agonist of the 5-HT1A receptor with a Ki value of 10.0 nM. It also binds to SERT, D2, and 5-HT6 receptors with Ki values of 2.8 nM, 23 nM, and 192 nM, respectively. Furthermore, this compound demonstrates stability in microsomes and induces hypothermia in mice.Formule :C31H31N5O3Couleur et forme :SolidMasse moléculaire :521.61Neurokinin A(4-10)
CAS :Neurokinin A(4-10)(TFA) is an agonist of tachykinin NK2 receptor .Formule :C34H54N8O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :766.91BIMU 8
CAS :BIMU 8 is a selective agonist of 5-HT4 with EC50s of 18 nM, 77 nM, and 540 nM for wild-type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4.Formule :C19H27ClN4O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :378.9Ref: TM-T21946
1mg85,00€5mg168,00€1mL*10mM (DMSO)175,00€10mg235,00€25mg394,00€50mg582,00€100mg827,00€500mg1.674,00€Octodrine
CAS :Octodrine (2-Amino-6-methylheptane) is primarily used as a pharmaceutical intermediate for Octamylamine; it also functions as a local anesthetic and vasoconstrictor.Formule :C8H19NDegré de pureté :99.98%Couleur et forme :Clear Colorless To Light Yellow LiquidMasse moléculaire :129.24CB2 receptor agonist 2
CAS :CB2 receptor agonist 2 (ZINC72105556): potent, Ki=8.5 nM, high selectivity for CB2.
Formule :C30H36N2O4Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :488.62[D-Trp34]-Neuropeptide Y Acetate
[D-Trp34]-Neuropeptide Y Acetate is a potent Y5 receptor agonist that increases rat food intake; less potent at Y1, Y2, Y4, Y6.Formule :C198H293N55O58Degré de pureté :99.73%Couleur et forme :SoildMasse moléculaire :4371.78WAY-620645
CAS :WAY-620645 is a CCK antagonist with antitumor and analgesic activities.Formule :C22H22N4O2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :374.44Ref: TM-T9991
1mg38,00€5mg85,00€1mL*10mM (DMSO)104,00€10mg111,00€25mg224,00€50mg318,00€100mg462,00€200mg627,00€Des His1, Glu8 Exendin-4
Des His1, Glu8 Exendin-4 is a glucagon-like peptide-1 receptor (GLP1R) antagonist that regulates blood glucose and is used in the study of diabetes and obesity.Formule :C179H277N47O59SDegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :4063.46LCKLSL acetate
LCKLSL acetate is a potent AnxA2 inhibitor, blocking tPA binding and plasmin production, with anti-angiogenic effects.Formule :C32H61N7O10SDegré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :735.93R 396
CAS :R 396 (Acleu-asp-gln-trp-phe-glynh2) is a linear hexapeptide and is also an NK-2 tachykinin receptor antagonist.Formule :C39H51N9O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :805.88BMS 193885
CAS :BMS 193885 is a selective and competitive neuropeptide Y(1) receptor antagonist with affinity of 3.3 nM.Formule :C36H48N4O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :680.79Orexin A (human, rat, mouse) acetate
Orexin A (human, rat, mouse) acetate (Hypocretin-1 (human, rat, mouse) acetate) is an excitatory neuropeptide with analgesic properties.Formule :C154H247N47O46S4Couleur et forme :SolidMasse moléculaire :3621.15Survodutide TFA
Survodutide TFA (BI 456906 TFA) is a GCGR/GLP-1R dual agonist, a peptide compound used in obesity research.Formule :C192H289N47O61·xC2HF3OC2Degré de pureté :99.29% - 99.96%Couleur et forme :SolidMasse moléculaire :4231.62 (free base)QWF acetate
QWF acetate is a Substance P antagonist peptide that specifically inhibits the binding to its receptor, NK1, and inhibits the activation of MRGPRX2.
Formule :C40H47N5O10Degré de pureté :96.65%Couleur et forme :SolidMasse moléculaire :757.84N-Nitroso Atenolol
CAS :N-Nitroso Atenolol is a derivative of Atenolol. At concentrations ranging from 0.1 to 1 mM, it induces DNA fragmentation in rat hepatocytes.Formule :C14H21N3O4Couleur et forme :SolidMasse moléculaire :295.33(±)-9-Nor-9α-hydroxy Hexahydrocannabinol
CAS :(±)-9-Nor-9α-hydroxy Hexahydrocannabinol is a cannabinoid-structured compound that exhibits potent cannabinoid-like activity in both dogs and mice.Formule :C20H30O3Couleur et forme :SolidMasse moléculaire :318.45sGC activator 2
sGC activator 2 (Compound 16a) acts as an activator of soluble guanylate cyclase (sGC), enhancing the production of cGMP and exhibiting vasoprotective and anti-inflammatory properties.Formule :C21H21FN8O3Couleur et forme :SolidMasse moléculaire :452.44UKH-1114
CAS :UKH-1114 is a potent σ2 receptor/Tmem97 agonist with a Ki value of 46 nM, demonstrating antinociceptive effects against mechanical hypersensitivity. This compound alleviates mechanical hypersensitivity in mice caused by nerve injury without inducing motor impairment and is a promising candidate for neuropathic pain research.Formule :C22H24F3NOCouleur et forme :SolidMasse moléculaire :375.438-Chloro caffeine
CAS :8-Chloro caffeine binds to adenosine receptors with a Ki of 30 µM. It enhances UV-induced chromosomal aberrations in the Cl-I type Chinese hamster embryo lung cells. 8-Chloro caffeine is a derivative of the methylxanthine alkaloid caffeine.Formule :C8H9ClN4O2Couleur et forme :SolidMasse moléculaire :228.64Methylhexanamine hydrochloride
CAS :Methylhexanamine hydrochloride is a fatty amine and vasoconstrictor that functions as a nasal decongestant when inhaled through the nasal mucosa.Formule :C7H18ClNCouleur et forme :SolidMasse moléculaire :151.682,6-DMA hydrochloride
CAS :2,6-DMA hydrochloride is a phenethylamine and acts as an agonist of the serotonin 5-HT2 receptor, with a pA2 value of 5.09.Formule :C11H18ClNO2Couleur et forme :SolidMasse moléculaire :231.728β-Hydroxy-exo-THC
CAS :8β-Hydroxy-exo-THC, a cannabinoid ether analog, exhibits weak affinity for receptor sites with an IC50 of 1.2 μM.Formule :C21H30O3Couleur et forme :SolidMasse moléculaire :330.46δ8-THC acetate
CAS :Delta8-THC acetate (Delta8-tetrahydrocannabinol) is a psychoactive cannabinoid that binds to the cannabinoid receptor 1 (CB1 receptor) and exhibits anti-nausea, appetite-stimulating, and anti-inflammatory effects. It may also offer neuroprotective benefits and has potential applications in research on anxiety and depression.Formule :C23H32O3Couleur et forme :SolidMasse moléculaire :356.5Methamnetamine hydrochloride
CAS :Methamnetamine (PAL-1046) hydrochloride is a psychoactive substance derived from phenethylamine, known to cause excessive serotonin release.Formule :C14H18ClNCouleur et forme :SolidMasse moléculaire :235.75PAF C-18
CAS :PAF C-18 is a natural phospholipid molecule belonging to the platelet-activating factor (PAF) family,, involved in hemostasis and thrombosis by binding to PAFR.Formule :C28H58NO7PDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :551.74BAY-6672
CAS :BAY-6672 is, a selective,oral, highly potent human prostaglandin F (FP) receptor antagonist, exerts antifibrotic effects by inhibiting PGF₂α activity.Formule :C26H27BrClN3O3Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :544.87AD353
AD353 is a selective sigma-1 receptor ligand. It demonstrates high efficacy in models of capsaicin-induced allodynia and PGE2-induced mechanical hyperalgesia. Additionally, AD353 exhibits favorable pharmacokinetic properties.Formule :C23H30N2O2Couleur et forme :SolidMasse moléculaire :366.5PF-4363467
CAS :PF-4363467 is a dopamine D3/D2 receptor antagonist that reduces opioid-seeking behavior without the side effects associated with D2 receptors. It has a Ki value of 3.1 nM for D3R and 692 nM for D2R.Formule :C22H30N2O3SCouleur et forme :SolidMasse moléculaire :402.55Casopitant
CAS :Casopitant (GW679769) is an orally active neurokinin-1 (NK1) receptor antagonist, researched for its potential use in managing chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV).Formule :C30H35F7N4O2Couleur et forme :SolidMasse moléculaire :616.616-Fluoro-N,N-diethyltryptamine
CAS :6-Fluoro-N,N-diethyltryptamine (6-F-DET) exhibits affinity for the 5-HT2A receptor.Formule :C14H19FN2Couleur et forme :SolidMasse moléculaire :234.3117-TFM-PGF1α
CAS :17-TFM-PGF1α (Compound 8) is a saturated prostaglandin analog. It exhibits a high affinity and receptor selectivity for the human prostaglandin F receptor (hFP receptor), with an EC50 of 85 nM.Formule :C24H35F3O5Couleur et forme :SolidMasse moléculaire :460.53Eloralintide
CAS :Eloralintide (LY 3841136) is an AMYR agonist, anticipated for research in type 2 diabetes and obesity.Formule :C201H319N49O65S2Couleur et forme :SolidMasse moléculaire :4526.1LTD4 antagonist 2
CAS :LTD4 antagonist 2 (compound 6) functions as a leukotriene D4 (LTD4) antagonist with an IC50 of 2.8 μM for the cysteinyl leukotriene 1 receptor (CysLT1R). Additionally, it acts as an agonist for the G protein-coupled bile acid receptor 1 (GPBAR1), making it applicable for research into colitis, metabolic syndrome, and other GPBAR1- and CysLT1R-related diseases.Formule :C17H13NO3Couleur et forme :SolidMasse moléculaire :279.29S1R agonist 2
CAS :S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.Formule :C21H27NODegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :309.45Pafenolol
CAS :Pafenolol is a P-glycoprotein modulator with a Ki value of 5.5 µM. pafenolol is an orally available and selective beta-adrenergic receptor antagonist.Formule :C18H31N3O3Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :337.46Arotinolol hydrochloride
CAS :Arotinolol HCl is a non-selective α/β-blocker, anti-hypertensive, anti-obesity, and improves aortic stiffness.Formule :C15H22ClN3O2S3Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :408FFN246
CAS :FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation andFormule :C15H13FN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :256.27Emoghrelin
CAS :Emoghrelin, extracted from Heshouwu (Polygonum multiflorum), promotes the secretion of growth hormone by activating the ghrelin receptor [1].Formule :C24H22O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :518.42α-CGRP (mouse, rat) TFA
α-CGRP (mouse, rat) TFA, a neuropeptide belonging to the calcitonin gene-related peptide (CGRP) family, is predominantly located at neuromuscular junctions andFormule :C162H262N50O52S2·C2HF3O2Degré de pureté :98%Couleur et forme :SolidPSB-1114 triethylamine
PSB-1114 triethylamine is a potent, enzymatically stable, P2Y2 receptor agonist with a 134 nM EC50, exhibiting greater than 50-fold selectivity over P2Y4 (EC50Formule :C10H15F2N3O13P3S·xC6H15NDegré de pureté :98%Couleur et forme :Solid(Leu31,Pro34)-Peptide YY (human) (TFA)
"(Leu31,Pro34)-Peptide YY (human) (TFA) is the trifluoroacetic acid (TFA) form of (Leu31,Pro34)-Peptide YY (human), a derivative of Peptide YY that acts as aFormule :C195H296N54O56·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4292.75 (free base)Mibenratide TFA
Mibenratide TFA, a small cyclic peptide, functions as an adrenergic β1 receptor antagonist and has potential applications in heart failure research [1].Degré de pureté :98%Couleur et forme :Odour Solid(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin
CAS :(d(CH2)5[Tyr(Me)2, Dab5]AVP), a vasopressin V1a receptor-specific antagonist, demonstrates a pA2 value of 6.71 [1].Formule :C52H76N14O11S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1137.38Invopressin
CAS :Invopressin (Compound 42), a vasopressin V1A receptor partial agonist (EC50: 1.0 nM), is utilized in research related to cirrhosis conditions such as bacterialFormule :C110H161N31O27S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2413.78Galanin-Like Peptide (rat)
CAS :Galanin-Like Peptide (rat), a neuropeptide comprising 60 amino acids, plays a crucial role in regulating feeding, body weight, and energy metabolism [1].Formule :C288H461N87O83SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :6502.34TCMCB07
CAS :TCMCB07, a cyclic nonapeptide, serves as an orally active, brain-penetrant antagonist of the melanocortin receptor 4 (MC4R), with significant implications inFormule :C63H87N15O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1230.46Sigma-1 receptor antagonist 5
Sigma-1 receptor antagonist 5 (compound 12), a 4-pyridylpiperidine derivative, exhibits analgesic properties through its antagonistic action on sigma receptorsFormule :C26H27N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :397.51CB2R agonist 2
CB2R agonist 2 (cis-17-para) is a CB2R agonist [1].Degré de pureté :98%Couleur et forme :Odour SolidPhoenixin-14
CAS :Phoenixin-14 (PNX-14), an active endogenous isoform, induces an anxiolytic effect by activating the AHA GnRH system in mice and protects against ischemia/
Formule :C75H110N18O20Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1583.78Uroguanylin (human)
CAS :Uroguanylin (human) serves as a natural ligand for the Guanylyl Cyclase C (GCC) receptor in metastatic colorectal cancer tumors and exhibits anti-tumor effectsFormule :C64H102N18O26S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1667.86LHRH
CAS :Luteinizing hormone-releasing hormone (LHRH) is a neuropeptide produced in the hypothalamus that plays a pivotal role in regulating reproduction and hasFormule :C55H74N16O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1183.27CB2R agonist 3
CB2R agonist 3, a potent activator of cannabinoid receptor 2 (CB2R), exhibits an EC50 value of 0.37μM, indicative of its significant role in the immune system [Degré de pureté :98%Couleur et forme :Odour SolidFGH31
FGH31 (Compound 24), a dopamine D4 agonist, exhibits potent and selective GRK2-dependency with a K i of 1.6 nM and partially activates β-arrestin [1].Formule :C33H36N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :520.66MRS7925
MRS7925 (Compound 43) serves as a potent antagonist of the 5-HT2B receptor, with an inhibition constant (Ki) of 17 nM, and is utilized in the study of fibrosisFormule :C20H26IN5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :511.36[D-Pro2] Spantide I TFA
[D-Pro2] Spantide I TFA is an analog of Spantide I, a selective antagonist of the NK1 receptor [1].Formule :C75H108N20O13·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidTetrapeptide-1
CAS :Tetrapeptide-1 is a bioactive peptide renowned for its antioxidant properties and has been cited as an ingredient in cosmetics [1].Formule :C20H36N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.52PSB 0777 ammonium hydrate
PSB 0777 ammonium hydrate is a potent and selective adenosine A2A receptor full agonist, exhibiting K i values of 44.4 nM for rat A2A receptors and 360 nM forFormule :C18H20N5O7S2·NH4·75H2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :532.09D3R ligand 1
D3R Ligand 1 (compound 23b) is a potent, selective antagonist of the dopamine D3 receptor (Ki=66 nM), incorporating a THPB template.Formule :C27H37NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :455.59PZ-1922
PZ-1922 (Compound 16), able to cross the blood-brain barrier, is a dual antagonist for 5-HT6R and 5-HT3R with K i values of 17 nM and 0.45 nM, respectively.Degré de pureté :98%Couleur et forme :Odour SolidACTH (7-38) (human)
CAS :ACTH (7-38) (human) is a fragment (7-38) of the full human adrenocorticotropic hormone (ACTH (1-39)), also referred to as corticotropin inhibitory peptide (CIPFormule :C167H257N47O46Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3659.11Atrial natriuretic peptide (3-28) (human)
CAS :Atrial natriuretic peptide (3-28) (human) (ANP (3-28) (human)), a peptide hormone produced by the atrial myocardium, plays a critical role in the regulation ofFormule :C118H187N43O36S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2880.21Conopeptide rho-TIA
CAS :Conopeptide rho-TIA, a peptide from Conus tulipa venom, acts as a selective, noncompetitive inhibitor at the human α1B-Adrenergic Receptor and as a competitiveFormule :C105H160N36O21S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2390.884-Methylhistamine
CAS :4-Methylhistamine serves as a potent agonist for the histamine 4 receptor (H4R), holding promise for research into immune-related diseases, including cancer andFormule :C6H11N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :125.17NXT-10796
NXT-10796 is an orally active, intestinally restricted agonist of the EP4 receptor [1].Formule :C23H31N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :445.51Galanin (1-13)-Neuropeptide Y (25-36) amide
CAS :Galanin (1-13)-Neuropeptide Y (25-36) amide exhibits high-affinity binding to galanin receptors, similar to that of galanin itself [1].Formule :C136H209N41O34Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2962.37Ac-(d-Arg)-CEH-(d-Phe)-RWC-NH2
CAS :Ac-DArg-c[Cys-Glu-His-DPhe-Arg-Trp-Cys]-NH2 is a synthetic cyclic octapeptide that exhibits melanocortin-4 receptor (MC4R) agonism and has been shown toFormule :C51H70N18O11S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1175.35GRP (14-27) (human, porcine, canine)
CAS :GRP (14-27) (human, porcine, canine) functions as a ligand for bombesin receptors, with its specific binding being inhibited by GTP and GDP, while GMP does notFormule :C75H110N24O16S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1667.96Sigma-1 receptor antagonist 4
Sigma-1 receptor antagonist 4 (Compound 32) is a potent σ1R antagonist that significantly enhances morphine's analgesic effects and reverses morphine-inducedFormule :C22H26N2OCouleur et forme :SolidMasse moléculaire :334.45PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)
PACAP (6-27) is an antagonist for PACAP receptors with varying IC50s; blocks cAMP in neuroblastoma and breast cancer cells.Couleur et forme :LiquidCorticotropin-releasing factor (human) acetate
Corticotropin-releasing factor (human) acetate stimulates to synthesize and secret adrenocorticotropin in the anterior pituitary.Degré de pureté :98.30%Couleur et forme :LiquidPACAP-38 (31-38), human, mouse, rat acetate
PACAP-38 (31-38) acetate stimulates PAC1 receptor and boosts NPY and catecholamine in sympathetic neurons.Formule :C49H87N17O13Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :1122.32Nα-Methylhistamine FA
Nα-Methylhistamine FA is a histamine H3 receptor agonistFormule :C7H13N3O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :171.2Tirzepatide
CAS :Tirzepatide (LY-3298176) is a dual glucose-dependent polypeptide (GIP) (EC50=0.042 nM) and glucagon-like peptide-1 (GLP-1) (EC50=0.086 nM) receptor agonist.Formule :C225H348N48O68Degré de pureté :99.52% - 99.99%Couleur et forme :SolidMasse moléculaire :4813.45Meclinertant
CAS :Meclinertant: selective NTS1 antagonist, blocks Ca2+ mobilization, with anxiolytic and anti-addictive properties.Formule :C32H31ClN4O5Degré de pureté :97.51% - 99.44%Couleur et forme :SolidMasse moléculaire :587.07Tiaspirone hydrochloride
CAS :Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity and influences the electrophysiological activity of dopaminergic neurons.Formule :C24H33ClN4O2SDegré de pureté :99.87%Couleur et forme :SoildMasse moléculaire :477.06Tamsolusin Hydrochloride
CAS :Tamsolusin Hydrochloride (YM 12617) is a highly selective alpha-1A adrenergic receptor antagonist used in the treatment of benign prostatic hypertrophy.Formule :C20H29ClN2O5SDegré de pureté :99.92%Couleur et forme :SoildMasse moléculaire :444.97BM213 acetate
BM213 acetate is a selective C5aR1 agonist with antitumor activity that induces C5aR1-mediated calcium mobilization and pERK1/2 signaling.
Formule :C45H74N12O12Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :975.14RS 56812
CAS :RS 56812 is a 5-HT3 receptor antagonist and agonist used in the study of cognitive disorders.Formule :C18H21N3O2Degré de pureté :99.38%Couleur et forme :SoildMasse moléculaire :311.38Tiapride-d3
Tiapride-d3 is a deuterated form of Tiapride, a selective dopamine D2 receptor antagonist and an antipsychotic compound.Formule :C15H21D3N2O4SCouleur et forme :SolidMasse moléculaire :331.45Argipressin
CAS :Argipressin is a vasoconstrictive and antidiuretic hormone, binding to V1 receptors with Kd ~1.4 nM in rat heart and aortic cells.Formule :C46H65N15O12S2Degré de pureté :98%Couleur et forme :White PowderMasse moléculaire :1084.23L-798106
CAS :L-798106 (CM9) is an EP3 receptor antagonist that inhibits EP4, EP1, and EP2 receptors and attenuates PGE2-induced cough.Formule :C27H22BrNO4SDegré de pureté :98.97%Couleur et forme :SolidMasse moléculaire :536.44Granisetron
CAS :Granisetron, a serotonin receptor (5HT-3 selective) antagonist, is used as an antinauseant and antiemetic for cancer chemotherapy.
Formule :C18H24N4OCouleur et forme :SolidMasse moléculaire :312.41
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