GPCR/G-Protéine
Les inhibiteurs des GPCR/protéines G sont des composés qui ciblent les récepteurs couplés aux protéines G (GPCR) et les protéines G associées, qui jouent un rôle crucial dans la transmission des signaux de l'extérieur vers l'intérieur des cellules. Ces inhibiteurs sont essentiels pour étudier les voies de signalisation médiées par les GPCR, impliquées dans de nombreux processus physiologiques, y compris la perception sensorielle, la réponse immunitaire et la neurotransmission. Les inhibiteurs des GPCR sont également importants dans le développement de médicaments, car de nombreux agents thérapeutiques ciblent ces récepteurs. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de GPCR/protéines G de haute qualité pour soutenir vos recherches en pharmacologie, biologie cellulaire et domaines connexes.
Sous-catégories appartenant à la catégorie "GPCR/G-Protéine"
- récepteur 5-HT(1.025 produits)
- Récepteur d'adénosine(249 produits)
- Récepteur adrénergique(3.023 produits)
- Récepteur de la bombésine(35 produits)
- Récepteur de la bradykinine(61 produits)
- CXCR(158 produits)
- CaSR(34 produits)
- Récepteur cannabinoïde(217 produits)
- Cholécystokinine(1 produits)
- Récepteur de la dopamine(445 produits)
- Récepteur de l'endothéline(86 produits)
- Récepteur GNRH(84 produits)
- GPCR19(33 produits)
- GRK(33 produits)
- GTPase(23 produits)
- Récepteur du glucagon(194 produits)
- Hérisson/Smoothened(49 produits)
- Récepteur de l'histamine(385 produits)
- Récepteur LPA(21 produits)
- Récepteur de la mélatonine(26 produits)
- Récepteur OX(41 produits)
- Récepteur opioïde(327 produits)
- PAFR(14 produits)
- PKA(60 produits)
- Récepteur S1P(18 produits)
- SGLT(31 produits)
- Récepteur Sigma(46 produits)
Affichez 19 plus de sous-catégories
5988 produits trouvés pour "GPCR/G-Protéine"
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Diosuxentan
CAS :Diosuxentan is an inhibitor of ETA and is utilized in research pertaining to cardiovascular, renal, and neuronal inflammatory diseases.Formule :C20H21BrN6O7SCouleur et forme :SolidMasse moléculaire :569.39BAY-3153
CAS :BAY-3153 is a selective CCR1 ( C-C motif chemokine receptor 1 ) antagonist (human IC 50 =3 nM ; rat IC 50 =11 nM ; mice IC 50 =81 nM) .Formule :C25H29Cl2N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.42D1R antagonist 1
CAS :Compound 12a (D1R antagonist 1) is a D1R antagonist that participates in both G-protein-coupled and β-arrestin-mediated signaling pathways [1].Formule :C22H26BrNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :448.35(2R,3S)-Azelaprag
CAS :(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide is an Apelin receptor agonistFormule :C25H29N7O4SDegré de pureté :97.47% - >99.99%Couleur et forme :SoildMasse moléculaire :523.61Pentacosafluorotridecanoic Acid
CAS :Pentacosafluorotridecanoic Acid (PFTrDA) is a perfluoroalkyl substance (PFAS) that exhibits various biological impacts across different species. In zebrafish embryos, exposure to PFTrDA induces yolk sac edema and increases mRNA expression of thyroid hormone synthesis genes, including tshβ, at concentrations of 0.1 and 0.3 mg/L. At a dosage of 10 mg/kg, PFTrDA reduces serum testosterone and luteinizing hormone levels, as well as palmitic acid, linoleic acid, and oleic acid levels in the testicular interstitial cells of late adolescent rats. In humans, maternal plasma levels of PFTrDA during pregnancy are positively correlated with the development of eczema in female infants (but not male infants), and PFTrDA levels are higher in the livers of cancerous humans compared to non-cancerous ones. Additionally, PFTrDA is found in marine mammals.Formule :C13HF25O2Couleur et forme :SolidMasse moléculaire :664.11L 156903
CAS :L 156903 is a bioactive chemical. It also inhibits the binding of neurotensin to brain tissue.Formule :C35H41N7O5SCouleur et forme :SolidMasse moléculaire :671.81(+)-15-epi Cloprostenol
CAS :(+)-15-epi Cloprostenol is a synthetic analogue of prostaglandin F2α (PGF2α) and functions as a potent FP receptor agonist. The compound (+)-15-epi Cloprostenol is the 15(S) or 15β-hydroxy enantiomer of (+)-(+)-15-epi Cloprostenol. Compared to the 15(R)-(+)-15-epi Cloprostenol, this epimer exhibits significantly lower activity as an FP receptor ligand. However, the specific activity of this isomer remains inadequately studied.Formule :C22H29ClO6Masse moléculaire :424.92RWJ-68022
CAS :RWJ-68022 (Example 9) is a cyclopentene derivative that serves as a motilin receptor antagonist. It competes with motilin and erythromycin at motilin receptor sites and is applicable in research on gastrointestinal disorders.Formule :C34H37Cl3N4O4Couleur et forme :SolidMasse moléculaire :672.04UMB24
CAS :UMB24 is an effective antagonist of the σ2 receptor, exhibiting dissociation constants (Ki values) of 170 nM for the σ2 receptor and 322 nM for the σ1 receptor. This compound mitigates cocaine-induced convulsions and hyperactivity without causing mortality.Formule :C17H21N3Couleur et forme :SolidMasse moléculaire :267.37MK-8318
CAS :MK-8318 is an effective and selective antagonist of the CRTh2 receptor (Ki: 5.0 nM).Formule :C27H26F4N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :534.5GLP-1 receptor agonist 16
CAS :GLP-1 receptoragonist 16 (Example 53) is a GLP-1 agonist applicable for research in diabetes, obesity, or diseases related to non-alcoholic steatohepatitis.Formule :C33H31ClFN3O4Couleur et forme :SolidMasse moléculaire :588.068(R)-MrgprX2 antagonist-3
CAS :(R)-MrgprX2 antagonist-3 is an antagonist of MrgprX2. It is applicable in the study of inflammatory skin diseases. For more detailed information, please refer to compound E118 in patent document WO2021092240A1.Formule :C16H20FN3O2SMasse moléculaire :337.41Mrgx2 antagonist-3
CAS :Mrgx2 antagonist-3 (Compound B-40) is a highly selective antagonist of the MrgX2 receptor, with an IC50 range of 0.042-2.5 nM. It blocks downstream G protein signaling and β-arrestin recruitment, inhibiting Mrgx2 receptor-mediated calcium influx and cell degranulation. Mrgx2 antagonist-3 shows potential for research in inflammation-associated diseases and pruritus, such as chronic urticaria and allergic asthma.Formule :C15H15F2N3OCouleur et forme :SolidMasse moléculaire :291.30GRK6-IN-5
CAS :GRK6-IN-5 is an inhibitor of the GRK6 polypeptide, with an IC50 of 4.48 μM. GRK6-IN-5 is utilized in research focused on hematological malignancies, inflammatory diseases, and autoimmune disorders.Formule :C23H21N3O2Couleur et forme :SolidMasse moléculaire :371.432Alixorexton
CAS :Alixorexton is an agonist of the orexin-2 receptor (orexin-2 receptor) and is utilized in obesity research.Formule :C21H30N2O5SCouleur et forme :SolidMasse moléculaire :422.538Edonentan hydrate
CAS :Edonentan (BMS 207940) hydrate effectively blocks the endothelin A (ETA) receptor as a potent and selective antagonist, featuring a K i of 10 pM. It exhibits complete (100%) oral bioavailability in rats [1].Formule :C28H34N4O6SCouleur et forme :SolidMasse moléculaire :554.66GLP-1R modulator-1
CAS :GLP-1R modulator-1 (Compound 384) is a potent and orally active selective agonist of the glucagon-like peptide-1 receptor (GLP-1R). It activates G protein-coupled signaling, leading to increased intracellular cAMP levels, enhanced insulin secretion, delayed gastric emptying, and reduced appetite. GLP-1R modulator-1 holds potential for research in type 2 diabetes, obesity, and non-alcoholic steatohepatitis (NASH).Formule :C41H38ClFN6O4Couleur et forme :SolidMasse moléculaire :733.23MRGPRX2 modulator-1
CAS :MRGPRX2 modulator-1 (example 17), a modulator of the mas-related G-protein receptor X2 (MRGPRX2), is employed in studies focused on inflammation, pain, and autoimmune disorders [1].Formule :C20H19F6N5OCouleur et forme :SolidMasse moléculaire :459.39Rivenprost
CAS :Rivenprost, selective EP4 agonist (Ki: 0.7 nM), promotes bone growth, osteoblast differentiation, and aids wound healing.Formule :C24H34O6SCouleur et forme :SolidMasse moléculaire :450.59Metrazoline
CAS :Metrazoline (o-Methyl-tracizoline) acts as a ligand for adrenergic receptors (low affinity) and imidazoline I2 receptors.
Formule :C14H16N2O4Couleur et forme :SolidMasse moléculaire :276.288Udifitimod
CAS :Udifitimod (BMS-986166) is a potent, selective, and orally active modulator of the S1P1R receptor, showing potential for research in autoimmune diseases.Formule :C25H33NO2Couleur et forme :SolidMasse moléculaire :379.54SPL-IN-1
CAS :SPL-IN-1 (compound C17) acts as a dual species inhibitor of sphingosine-1-phosphate lyase [1].Formule :C31H42N2O6S2Couleur et forme :SolidMasse moléculaire :602.8AZD5462
CAS :AZD5462 is a potent orally available relaxin receptor RXFP1 agonist for the study of heart failure and cancer.Formule :C30H41FN2O6Degré de pureté :98.32% - 99.63%Couleur et forme :SolidMasse moléculaire :544.65BMS-986141
CAS :BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614Formule :C27H23N5O5S2Degré de pureté :98.43% - 99.26%Couleur et forme :SolidMasse moléculaire :561.63PF-07258669
CAS :PF-07258669 is a selective melanocortin 4 receptor (MC4) antagonist used in the study of cachexia and loss of appetite.Formule :C25H27FN6O2Degré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :462.52BQ-788
CAS :BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation of coronary perfusion pressure.Formule :C34H51N5O7Degré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :641.8Ref: TM-T10595
1mg130,00€2mg178,00€5mg313,00€1mL*10mM (DMSO)341,00€10mg447,00€25mg713,00€50mg964,00€100mg1.305,00€500mg2.592,00€Treprostinil diethanolamine
CAS :Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1 and IP, with values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1,Formule :C27H45NO7Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :495.65LSN3318839
CAS :LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and canFormule :C26H23Cl2N3O2Degré de pureté :99.70%Couleur et forme :SolidMasse moléculaire :480.39Vofopitant dihydrochloride
CAS :Vofopitant dihydrochloride (GR 205171A) is a tachykinin NK1 receptor antagonist and a potential compound for the treatment of pathologic vomiting.Formule :C21H25Cl2F3N6ODegré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :505.36Ref: TM-T13329L
1mg94,00€5mg222,00€1mL*10mM (DMSO)248,00€10mg356,00€25mg675,00€50mg1.009,00€100mg1.378,00€500mg2.673,00€AZD-5672
CAS :AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM.Formule :C32H38F2N2O5S2Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :632.78Ref: TM-T30260
1mg192,00€5mg434,00€1mL*10mM (DMSO)530,00€10mg610,00€25mg888,00€50mg1.243,00€100mg1.693,00€Dersimelagon
CAS :Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist.Cost-effective and quality-assured.Formule :C36H45F4N3O5Degré de pureté :97.35% - 98.23%Couleur et forme :SolidMasse moléculaire :675.75Vofopitant
CAS :Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for the study of post-traumatic stress disorder (PTSD).Formule :C21H23F3N6ODegré de pureté :97.86%Couleur et forme :SolidMasse moléculaire :432.44SB-423562
CAS :SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis.Formule :C26H32N2O4Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :436.54Ref: TM-T12846
1mg37,00€5mg80,00€1mL*10mM (DMSO)89,00€10mg119,00€25mg210,00€50mg319,00€100mg442,00€200mg605,00€SB-224289 hydrochloride
CAS :SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.Formule :C32H33ClN4O3Degré de pureté :98.99% - 99.96%Couleur et forme :SolidMasse moléculaire :557.08Rolapitant hydrochloride
CAS :Rolapitant HCl is a potent NK1 antagonist, non-CYP3A4 interactive, with anti-emetic effects and a Ki of 0.66 nM.Formule :C25H27ClF6N2O2Degré de pureté :98.35% - 99.79%Couleur et forme :SolidMasse moléculaire :536.94Ref: TM-T3724
1mg153,00€5mg365,00€1mL*10mM (DMSO)439,00€10mg520,00€25mg780,00€50mg1.054,00€100mg1.425,00€200mg1.882,00€CYM 9484
CAS :CYM 9484 is a selective and potent neuropeptide Y (NPY) Y2 receptor antagonist with an IC50 value of 19 nM.Formule :C27H31N3O3S2Couleur et forme :SolidMasse moléculaire :509.68JMV 2959
CAS :JMV 2959 is an antagonist of growth hormone secretagogue receptor type 1a (GHS-R1a) (IC50: 32 nM).Formule :C30H32N6O2Couleur et forme :SolidMasse moléculaire :508.61HOKU-81
CAS :HOKU-81is a new bronchodilator and is one of the metabolites of tulobuterol.Formule :C12H18ClNO2Couleur et forme :SolidMasse moléculaire :243.73SR 146131
CAS :SR 146131 is a potent and selective agonist of the nonpeptide receptor.Formule :C32H36ClN3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :610.167-Desmethyl-agomelatine
CAS :7-Desmethyl-agomelatine, a metabolite of Agomelatine, exhibits lower activity than Agomelatine, which functions as a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist.Formule :C14H15NO2Couleur et forme :SolidMasse moléculaire :229.27Protease-Activated Receptor-4
CAS :Protease-Activated Receptor-4 (PAR4) is a proteinase-activated receptor-4 agonist used in antiplatelet therapy.Formule :C33H46N8O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :666.77ML-290
CAS :ML-290 is an effective relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes. It shows an EC50 of 94 nM.Formule :C24H21F3N2O5SCouleur et forme :SolidMasse moléculaire :506.49SB-399885 hydrochloride
CAS :SB-399885 hydrochloride is an antagonist of 5-HT6 receptor.Formule :C18H22Cl3N3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :482.81BIBP3226 TFA
CAS :BIBP3226 TFA is an effective and selective antagonist of neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor (Kis: 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF).Formule :C29H32F3N5O5Couleur et forme :SolidMasse moléculaire :587.59ML-00253764 hydrochloride
CAS :ML-00253764 hydrochloride is an antagonist of nonpeptidic melanocortin receptor 4 (MC4R) (Ki and IC50 of 0.16 µM and 0.103 µM, respectively).Formule :C18H19BrClFN2OCouleur et forme :SolidMasse moléculaire :413.71Beraprost sodium
CAS :Beraprost sodium is a stable and orally active prodrug of PGI2.Formule :C24H29NaO5Couleur et forme :SolidMasse moléculaire :420.481Arotinolol
CAS :Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand [125I-ICYP] to [5HT1B-serotonergic] receptor sites. It is an antihypertensive agent.Formule :C15H21N3O2S3Couleur et forme :White SolidMasse moléculaire :371.54Pumosetrag Hydrochloride
CAS :Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.Formule :C15H18ClN3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :339.84Patecibart
CAS :Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the endothelin receptor A (EDNRA).
Degré de pureté :98%Couleur et forme :Liquid3-Hydroxybenzylamine
CAS :3-Hydroxybenzylamine is a useful organic compound for research related to life sciences. The catalog number is T124305 and the CAS number is 73604-31-6.Formule :C7H9NOCouleur et forme :SolidMasse moléculaire :123.155GSK-3050002
GSK-3050002 (HGS-1035) is a humanized IgG1 antibody that targets and binds to CCL20. It holds potential for inflammation research. For isotype control, refer to Human IgG1 kappa, Isotype Control.
Couleur et forme :Odour LiquidN-methyl-2-AI (hydrochloride)
CAS :N-methyl-2-AI (hydrochloride) is a useful organic compound for research related to life sciences. The catalog number is T66396 and the CAS number is 10408-85-2.Formule :C10H14ClNCouleur et forme :SolidMasse moléculaire :183.68dapitant
CAS :Dapitant, a non-peptide, selective antagonist of human NKI receptors, is representative of the 7,7,4-triarylperhydroisoindol-4-ols.Formule :C37H39NO4Couleur et forme :SolidMasse moléculaire :561.71Vornorexant
CAS :Vornorexant (ORN-0829; TS-142) is a potent dual OX1R and OX2R antagonist with IC50 values of 1.05 nM and 1.27 nM, respectively. It exhibits potent sleep-promoting effects in vivo and can be used for insomnia treatment research.Formule :C23H22FN7O2Couleur et forme :SolidMasse moléculaire :447.4744-Hydroxyatomoxetine
CAS :4-Hydroxyatomoxetine, an active metabolite of Atomoxetine, is metabolized by CYP2D6. Atomoxetine is a noradrenaline reuptake inhibitor.Formule :C17H21NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :271.351-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol
CAS :1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol is a useful organic compound for research related to life sciences. The catalog number is T65156 and the CAS number is 24155-42-8.Formule :C11H10Cl2N2OCouleur et forme :SolidMasse moléculaire :257.11Goserelin acetate(65807-02-5 Free base)
Goserelin acetate （ICI-118630 acetate） is a naturally occurring decapeptide, a GnRH (gonadotropin releasing hormone) agonist that reduces the production of sex hormones (testosterone and estrogen) for the treatment of prostate cancer, breast cancer and endometriosis.
Degré de pureté :99.77%Couleur et forme :Odour Solid(Rac)-Zevaquenabant
CAS :(Rac)-Zevaquenabant ((Rac)-MRI-1867, compound 6b) is a potent and selective antagonist of cannabinoid receptor type 1 (CB1R) and inducible nitric oxide synthase (iNOS), with a binding affinity (Ki) of 5.7 nM for CB1R. It holds promise as an investigative tool in liver fibrosis research due to these characteristics.Formule :C25H21ClF3N5O2SCouleur et forme :SolidMasse moléculaire :547.98TAK-683
CAS :TAK-683: a full KISS1R agonist, IC50=170 pM; a nonapeptide metastin analog with human EC50=0.96 nM, rat EC50=1.6 nM.Formule :C64H83N17O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1298.45Sarizotan
CAS :Sarizotan (EMD 128130) is an orally active compound that acts as an agonist for serotonin 5-HT 1A receptors and dopamine receptors, with IC50 values of 6.5 nM for rat 5-HT 1A, 0.1 nM for human 5-HT 1A, 15.1 nM for rat D 2, 17 nM for human D 2, 6.8 nM for human D 3, and 2.4 nM for human D 4.2.Formule :C22H21FN2OCouleur et forme :SolidMasse moléculaire :348.4216-Chloro-5-(2-chloroethyl)indolin-2-one
CAS :6-Chloro-5-(2-chloroethyl)indolin-2-one is a useful organic compound for research related to life sciences. The catalog number is T64862 and the CAS number is 118289-55-7.Formule :C10H9Cl2NOCouleur et forme :SolidMasse moléculaire :230.09BRL 15572
CAS :BRL 15572 is a useful organic compound for research related to life sciences. The catalog number is T64501 and the CAS number is 734517-40-9.Formule :C25H27ClN2OCouleur et forme :SolidMasse moléculaire :406.95Propiram fumarate HCl
CAS :Propiram fumarate HClis an orally available Opioid receptors agonist with analgesic activity for the study of musculoskeletal pain.
Formule :C16H25N3O·xClHDegré de pureté :99.25%Couleur et forme :SoildCRTh2 antagonist 3
CAS :CRTh2 antagonist 3, a potent molecule, activates PDK1 (EC50=2μM, Kd=8.4μM) and may cause cardiovascular inflammation.Formule :C19H20N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.44Anti-GLP1R Antibody
Anti-GLP1R Antibody is a human antibody expressed in CHO cells, targeting GLP1R. For isotype controls, refer to Human IgG1 kappa, Isotype Control.
Couleur et forme :Odour LiquidBX471 hydrochloride
CAS :BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist with a Ki of 1 nM for human CCR1, exhibiting 250-fold selectivity over CCR2, CCR5, and CXCR4.Formule :C21H25Cl2FN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :471.351-Oleoyl Lysophosphatidic Acid
CAS :1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can be used to study cancer and atherosclerosis.
Formule :C21H41O7PCouleur et forme :SolidMasse moléculaire :436.52Amelubant
CAS :Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315 with anti-inflammatory activity[1]. It is a potent, oral, long-acting LTB4 receptor antagonist that negligibly binds to the LTB4 receptor, exhibiting Kis of 221 nM and 230 nM in vital cells and membranes.Formule :C33H34N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :538.63SKF 89748
CAS :SKF 89748 is an agonists of alpha 1-adrenoceptor.Formule :C12H17NOSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :223.33Desmethyl cariprazine
CAS :Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).Formule :C20H30Cl2N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :413.384-Hydroxypropranolol hydrochloride
CAS :4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, with a potency comparable to Propranolol. It inhibits β1- and β2-adrenergic receptors (pA2s: 8.24 and 8.26).Formule :C16H22ClNO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :311.80(R)-(-)-α-Methylhistamine dihydrochloride
CAS :R(-)-alpha-Methylhistamine 2HCl is an effective and selective agonist of the H3 histamine receptor.Formule :C6H13Cl2N3Couleur et forme :SolidMasse moléculaire :198.09TAK-448
CAS :TAK-448 (MVT-602), a potent KISS1R agonist, IC50: 460 pM, EC50: 632 pM, trialed for Prostate Cancer and Hypogonadism.Formule :C58H80N16O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1225.36Picumeterol
CAS :Picumeterol(GR 114297A) is a potent and selective β2 adrenergic receptor agonist. In vitro and in vivo trials, Picumeterol produced long-lasting airway smooth muscle relaxation. Picumeterol is a pure R enantiomer that can be used to improve lung function and reduce airway hyperreactivity in patients with asthma.Formule :C21H29Cl2N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :426.38Canagliflozin-d4
CAS :Canagliflozin D4 is a deuterium-labeled Canagliflozin. Canagliflozin is an SGLT2 inhibitor.
Formule :C24H25FO5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :448.54RU 24969 succinate
CAS :RU 24969 succinate, a 5-HT receptor agonist, exhibits K i values of 0.38 nM for 5-HT 1B and 2.5 nM for 5-HT 1A, indicating its affinity towards these receptors. It reduces fluid consumption and enhances forward locomotion. This compound is utilized in neurological disease research.
Formule :C18H22N2O5Couleur et forme :SolidMasse moléculaire :346.382-Methyl-5-HT hydrochloride
CAS :2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.Formule :C11H15ClN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :226.7Pamoic acid
CAS :Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.
Formule :C23H16O6Degré de pureté :99.99%Couleur et forme :Fine Yellow PowderMasse moléculaire :388.37GR 218,231
CAS :GR 218,231 is a selective antagonist of D3 dopamine receptor.Formule :C24H33NO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :415.59MEN11467
CAS :MEN11467 is a novel, orally available, potent and selective peptidomimetic tachykinin NK 1 receptor antagonist for the study of acute colon cancer.Formule :C38H40N4O3Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :600.75Neurokinin antagonist 1
CAS :Neurokinin antagonist 1 is a potent is a neuropeptide antagonist that can be used to study neurological disorders.Formule :C38H40N4O3Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :600.75Flumexadol
CAS :Flumexadol is a selective 5-HT2C receptor agonist with an affinity (Ki) of 25 nM for the (+)-enantiomer and exhibits 40-fold selectivity over the 5-HT2A receptor. It is an orally active, non-narcotic analgesic.Formule :C11H12F3NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :231.21Imetit dihydrobromide
CAS :Imetit dihydrobromide is a high affinity and effective agonist of histamine H3 and H4 receptors (Ki: 0.3 and 2.7 nM). Imetit mimics the histamine effect in triggering a shape change in eosinophils (EC50: 25 nM).Formule :C6H12Br2N4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :332.06SB251023
CAS :SB251023 is an agonist of β3-adrenoceptor.Formule :C28H34NO6PCouleur et forme :SolidMasse moléculaire :511.55AEF0117
CAS :AEF0117 is a signaling inhibitor of CB1-SSi that inhibits cannabinoid self-administration and can be used to study cannabis withdrawal.
Formule :C29H40O3Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :436.63Ref: TM-T79909
Produit arrêtéS1P1 agonist 6
CAS :Compound I (S1P1 agonist 6) is an S1P1 agonist that mitigates autoimmune activity by inhibiting lymphocyte trafficking and has potential as an immunosuppressive
Formule :C25H26F3NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :445.472-MNG
CAS :2-MNG (2-Mercaptonicotinoyl glycine) is a novel melanogenesis inhibitor. 2-MNG inhibits two mechanisms of UV-induced skin pigmentation in vivo.
Formule :C8H8N2O3SCouleur et forme :LiquidMasse moléculaire :212.23Ref: TM-T89029
Produit arrêtéDimethandrolone Undecanoate
CAS :Dimethandrolone Undecanoate (DMAU) is a novel orally available androgen with progestational activity and is a potential male contraceptive compound.Formule :C31H50O3Degré de pureté :99.65% - >99.99%Couleur et forme :SolidMasse moléculaire :470.73
