GPCR/G-Protéine
Les inhibiteurs des GPCR/protéines G sont des composés qui ciblent les récepteurs couplés aux protéines G (GPCR) et les protéines G associées, qui jouent un rôle crucial dans la transmission des signaux de l'extérieur vers l'intérieur des cellules. Ces inhibiteurs sont essentiels pour étudier les voies de signalisation médiées par les GPCR, impliquées dans de nombreux processus physiologiques, y compris la perception sensorielle, la réponse immunitaire et la neurotransmission. Les inhibiteurs des GPCR sont également importants dans le développement de médicaments, car de nombreux agents thérapeutiques ciblent ces récepteurs. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de GPCR/protéines G de haute qualité pour soutenir vos recherches en pharmacologie, biologie cellulaire et domaines connexes.
Sous-catégories appartenant à la catégorie "GPCR/G-Protéine"
- récepteur 5-HT(1.025 produits)
- Récepteur d'adénosine(251 produits)
- Récepteur adrénergique(3.028 produits)
- Récepteur de la bombésine(35 produits)
- Récepteur de la bradykinine(61 produits)
- CXCR(158 produits)
- CaSR(34 produits)
- Récepteur cannabinoïde(218 produits)
- Cholécystokinine(1 produits)
- Récepteur de la dopamine(445 produits)
- Récepteur de l'endothéline(86 produits)
- Récepteur GNRH(84 produits)
- GPCR19(36 produits)
- GRK(33 produits)
- GTPase(23 produits)
- Récepteur du glucagon(195 produits)
- Hérisson/Smoothened(49 produits)
- Récepteur de l'histamine(385 produits)
- Récepteur LPA(21 produits)
- Récepteur de la mélatonine(26 produits)
- Récepteur OX(41 produits)
- Récepteur opioïde(327 produits)
- PAFR(14 produits)
- PKA(61 produits)
- Récepteur S1P(18 produits)
- SGLT(31 produits)
- Récepteur Sigma(46 produits)
Affichez 19 plus de sous-catégories
6011 produits trouvés pour "GPCR/G-Protéine"
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BMS-604992
CAS :EX-1314 (BMS-604992) is a growth hormone secretagogue receptor (GHSR) agonist.Formule :C24H32ClN7O5Couleur et forme :SolidMasse moléculaire :534.01NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal)
CAS :Compound 39, an APJ receptor agonist, has a K i of 0.6 nM, activates Gαi1 (EC50 0.8 nM), recruits β-arrestin2 (EC50 31 nM), and affects heart function.Formule :C49H73N13O11Couleur et forme :SolidMasse moléculaire :1020.18GLP-1R agonist 10
CAS :GLP-1R agonist 10 is a GLP-1 agonist (EC50: 0.051 nM).Formule :C29H29ClFN5O4Couleur et forme :SolidMasse moléculaire :566.02N-5984 Hydrochloride
CAS :N-5984 Hydrochloride is a beta3-AR agonist.Formule :C20H23Cl2NO5Couleur et forme :SolidMasse moléculaire :428.31Amauromine
CAS :Amauromine is a peripherally selective and potent cannabinoid receptor type 1 (CB1) receptor antagonist, a novel alkaloid with vasodilatory activity.Formule :C32H36N4O2Couleur et forme :SolidMasse moléculaire :508.655-HT2C agonist-3
CAS :5-HT2C agonist-3 ((+)-19), a selective 5-HT2C agonist (EC 50: 24 nM, Ki: 78 nM), exhibits antipsychotic-like activity by blocking amphetamine-inducedFormule :C19H23ClFNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :351.84TA-1887
CAS :TA-1887: Selective SGLT2 inhibitor, treats type 2 diabetes, lowers glucose in high-fat diet mice, boosts UGE, has good pharmacokinetics.Formule :C24H26FNO5Couleur et forme :SolidMasse moléculaire :427.47(S)-Bexicaserin
CAS :(S)-Bexcaserin (compound 2) serves as a 5-HT2C receptor agonist, presenting research possibilities in obesity and psychiatric disorders [1].Formule :C15H19F2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :295.33Saredutant
CAS :Saredutant (SR 48968) is a selective neurokinin-2 (NK2) receptor antagonist that inhibits neurokinin A by blocking NK2 receptor, antidepressant and anxiolytic.Formule :C31H35Cl2N3O2Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :552.54Ref: TM-T16842
1mg118,00€5mg282,00€1mL*10mM (DMSO)341,00€10mg444,00€25mg785,00€50mg1.305,00€100mg1.728,00€TC-SP 14
CAS :TC-SP 14 (compound 14) is a potent, orally available S1P1 agonist with EC50 of 0.042 μM; minimal S1P3 binding (EC50 3.47 μM); reduces blood lymphocytes.Formule :C25H20F2N2O2SCouleur et forme :SolidMasse moléculaire :450.5Bexicaserin
CAS :Bexicaserin (Compound 3), a 5-HT2C receptor agonist, has potential applications in research pertaining to obesity and psychiatric disorders [1].Formule :C15H19F2N3OCouleur et forme :SolidMasse moléculaire :295.33Amesergide
CAS :Amesergide is an orally active and selective serotonin (5-HT1/2) antagonist that inhibits weight gain in offspring of female CD rats, for depression research.Formule :C25H35N3ODegré de pureté :100% - 99.54%Couleur et forme :SolidMasse moléculaire :393.56Aganepag isopropyl
CAS :Aganepag isopropyl can be used to treat Glaucoma.Formule :C27H37NO4SCouleur et forme :SolidMasse moléculaire :471.6513,14-dihydro-15-keto Prostaglandin E2
CAS :13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) serves as the predominant metabolite of PGE2 in plasma, created through a 15-keto PGE2 intermediate by the action of 15-oxo-PG Δ13 reductase. Unlike its precursor PGE2, this compound exhibits poor binding affinity towards EP2 and EP4 PGE2 receptors (Ki values of 12 and 57 µM, respectively) in CHO cells and fails to stimulate adenylate cyclase activity therein (EC50s >18 and >38 µM, respectively). Concentrations of 13,14-dihydro-15-keto PGE2 are notably higher in the plasma of pregnant women during their third trimester and at labor and delivery stages, whereas its levels are found to be reduced in the tumor tissues of patients with non-small cell lung cancer (NSCLC) compared to adjacent healthy tissue.Formule :C20H32O5Couleur et forme :SolidMasse moléculaire :352.5Cipralisant maleate
CAS :Cipralisant maleate is a potent, selective Histamine H3 receptor antagonist.Formule :C18H24N2O4Couleur et forme :SolidMasse moléculaire :332.39Abaperidone
CAS :Abaperidone is an atypical antipsychotic, antagonizes 5-HT2A (IC50=6.2 nM) and D2 receptors (IC50=17 nM), reduces hsp70 mRNA in rat brains.Formule :C25H25FN2O5Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :452.47Velusetrag
CAS :Velusetrag(TD-5108), a potent 5-HT4 agonist, is in development for gastroparesis, constipation, and IBS.Formule :C25H36N4O5SCouleur et forme :SolidMasse moléculaire :504.64APJ receptor agonist 6
CAS :APJ receptor agonist 6 is a potent agonist of the APJ (apelin receptor) (Ki: 0.059 μM). (EC50: 6.22 μM).Formule :C29H34FN3O5Couleur et forme :SolidMasse moléculaire :523.6FR-181157
CAS :FR-181157, a novel prostaglandin (PG) mimetic, shows high potency and agonist efficacy at the IP receptor and has good bioavailability.Formule :C30H27NNaO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :488.539NTNCB hydrochloride
CAS :NTNCB hydrochloride is an antagonist of neuropeptide Y (NPY) Y5 receptor.Formule :C25H34ClN3O4SDegré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :508.07GLP-1R agonist 3
CAS :GLP-1R agonist 3 is a GLP-1R agonist, an imidazole derivative.GLP-1R agonist 3 can be used to study diabetes and obesity.Formule :C31H28FN5O4Degré de pureté :97.19%Couleur et forme :SolidMasse moléculaire :553.5811-keto Fluprostenol
CAS :11-Keto Fluprostenol, a potent analog of prostaglandin F2α (PGF2α), primarily interacts with the FP receptor. It is a structurally modified derivative of prostaglandin D2 (PGD2) designed to enhance its potency and extend its half-life. The compound is produced by oxidizing fluprostenol at the C-11 position, which results in 11-keto fluprostenol. This modification allows 11-keto Fluprostenol to exhibit moderate affinity for the CRTH2/DP2 receptor, though it shows negligible activity at the DP1 receptor, distinguishing its action from that of PGD2.Formule :C23H27F3O6Couleur et forme :SolidMasse moléculaire :456.458E-6123
CAS :E-6123 is an antagonist of platelet-activating factor (PAF) receptor.Formule :C23H22ClN5OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :451.97Neladenoson dalanate
CAS :Neladenoson dalanate (BAY-1067197), an oral Adenosine A1 receptor partial agonist, is safe with good pharmacokinetics for chronic heart disease.Formule :C35H34ClN7O4S2Couleur et forme :SolidMasse moléculaire :716.27PSB-10 hydrochloride
CAS :PSB-10 hydrochloride is a human adenosine A3 receptor antagonist.Formule :C16H15Cl4N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :435.14BMS-764459
CAS :BMS-764459 is a potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1).Formule :C19H21F2N5O3Couleur et forme :SolidMasse moléculaire :405.4MRS3558
CAS :MRS3558 is an agonist of A3 adenosine receptors.Formule :C20H20Cl2N6O3Couleur et forme :SolidMasse moléculaire :463.32CYM50260
CAS :CYM50260 is a potent and exquisitely selective agonist of sphingosine-1-phosphate 4 receptor (S1P4-R, EC50= nM) with no activity against S1P1-R, S1P2-R, S1P3-RFormule :C14H11Cl3FNO2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :350.6Ref: TM-T15031
1mg50,00€5mg105,00€1mL*10mM (DMSO)116,00€10mg170,00€25mg356,00€50mg533,00€100mg758,00€Vemtoberant
CAS :Vemtoberant is a β3 adrenergic antagonist used in β3-related disorder research like heart failure.Formule :C29H37N3O8S2Couleur et forme :SolidMasse moléculaire :619.75AC-099 hydrochloride
CAS :AC-099 hydrochloride is a full agonist of neuropeptide FF2 receptor NPFF2R and a partial agonist of neuropeptide FF1 receptor NPFF1R.Formule :C9H9Cl2F3N4Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :301.1GP3269
CAS :GP3269 is a selective, potent, orally active human adenosine kinase (AK) inhibitor (IC50: 11 nM) with anticonvulsant effects in rats.Formule :C23H21FN4O3Couleur et forme :SolidMasse moléculaire :420.44Butanoyl PAF
CAS :Oxidized low-density lipoprotein (oxLDL) encompasses low molecular weight entities that facilitate monocyte differentiation and activate polymorphonuclear leukocytes. A substance, recently isolated and purified from oxLDL and identified as azelaoyl PC, exemplifies this. Similarly, Butanoyl PAF, a compound closely related to azelaoyl PC, maintains over 10% of the agonist potency of platelet-activating factor (PAF). Notably, Butanoyl PAF's concentration in oxLDL surpasses that of enzymatically generated PAF by more than 100-fold, making it a significant signalling molecule within oxLDL.Formule :C28H58NO7PCouleur et forme :SolidMasse moléculaire :551.7Meclizine N-oxide
CAS :Meclizine N-oxide, a metabolite of the histamine H1 receptor antagonist meclizine (1), also acts as a degradation product and potential impurity in commercial meclizine preparations (2).Formule :C25H27ClN2OCouleur et forme :SolidMasse moléculaire :407Mitemcinal
CAS :Mitemcinal is a motilin agonist.Formule :C40H69NO12Couleur et forme :SolidMasse moléculaire :755.98Piribedil N-oxide
CAS :Piribedil N-oxide, a metabolite of the dopamine receptor agonist piribedil, represents a chemical compound involved in the metabolic processing of its parent compound, piribedil.Formule :C16H18N4O3Couleur et forme :SolidMasse moléculaire :314.34Des-4-fluorobenzyl Mosapride
CAS :Des-4-fluorobenzyl Mosapride, the main metabolite of mosapride, acts as a gastroprokinetic agent improving upper gastrointestinal (GI) motility by stimulating the serotonin receptor 4 (5-HT4; EC50= 74.2 nM, in guinea pig ileal longitudinal muscle myenteric plexus). It has been shown to increase colonic motility in dogs, horses, and guinea pigs in vivo. Mosapride, including this metabolite, is utilized in human and veterinary medicine to mitigate post-surgical and Parkinson's-induced constipation.Formule :C14H20ClN3O3Couleur et forme :SolidMasse moléculaire :313.78Prostaglandin F1β
CAS :PGF1β, a biochemical compound, functions as a pivotal mediator in inflammatory processes and plays an integral role in uterine contractions. It exhibits significant regulatory effects on platelet aggregation and vasodilation, demonstrating its critical importance in cardiovascular health. Additionally, PGF1β contributes to the regulation of kidney function and electrolyte balance, illustrating its widespread impact across various physiological systems.Formule :C20H36O5Couleur et forme :SolidMasse moléculaire :356.5BMS-763534
CAS :BMS-763534 is a potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1).Formule :C18H21ClF2N4O3Couleur et forme :SolidMasse moléculaire :414.83KUC-7322
CAS :Ritobegron is used as a selective β3-adrenoceptor agonist and the prodrug of the active compound, KUC-7322.Formule :C21H27NO5Couleur et forme :SolidMasse moléculaire :373.445-HT2A antagonist 1
CAS :5-HT2A antagonist 1, from US5728835A & JP 1007727, may treat gastrointestinal and circulatory issues.Formule :C26H28N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.53CB 65
CAS :CB 65 is a high affinity and selective CB2 receptor agonist with Ki values of 3.3 and > 1000 nM for CB2 and CB1 receptors respectively.Formule :C22H28ClN3O3Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :417.93AC-099
CAS :AC-099 (compound 3) serves as a selective full agonist at NPFF2R (EC50 = 1189 nM) and a partial agonist at NPFF1R (EC50 = 2370 nM).Formule :C9H8ClF3N4Couleur et forme :SolidMasse moléculaire :264.64FAUC-312
CAS :FAUC-312 is a potent and selective agonist of the dopamine D4 receptor.Formule :C21H26N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :334.46GR-127935
CAS :GR-127935 is a potent and selective 5-HT1B/1D receptor antagonist.Formule :C29H31N5O3Couleur et forme :SolidMasse moléculaire :497.59UNC9994
CAS :UNC9994 is a β-arrestin-biased dopamine D₂ receptor agonist (β-arrestin EC50 = 50 nM; Emax = 97%) with robust in vivo antipsychotic drug-like activities.Formule :C21H22Cl2N2OSCouleur et forme :SolidMasse moléculaire :421.38NAS-181
CAS :NAS-181 is a potent and selective rat 5-hydroxytryptamine 1B (r5-HT1B) antagonist (Ki: 47 nM).NAS-181 enhances the accumulation of 5-HTP in rat brain regions.Formule :C20H30N2O7SCouleur et forme :SolidMasse moléculaire :442.53IWP-051
CAS :IWP-051: potent oral sGC stimulator, >99% protein bound, stable, permeable, no Caco-2 efflux, potential for daily dose.Formule :C17H11F2N5O2Couleur et forme :SolidMasse moléculaire :355.3GLP-1R agonist 9
CAS :GLP-1R agonist 9 acts as a GLP-1R agonist, demonstrating efficacy with EC50 values of 1.1 nM and 11 nM against CHO GLP-1R Clone H6 and Clone C6, respectively.Formule :C32H30ClF2N3O5Couleur et forme :SolidMasse moléculaire :610.05NH2-c[X-R-L-S-X]-K-G-P-(D-2Nal)
CAS :Compound 40, a cyclic Ape13 analogue and potent APJ agonist (Ki 5.7 nM), shows Gα12-bias and longer half-life.Formule :C49H73N13O11Couleur et forme :SolidMasse moléculaire :1020.18UCB-35440
CAS :UCB-35440, a 5-lipoxygenase inhibitor and a histamine H1 receptor antagonist, is used potentially for the treatment of dermatitis.Formule :C31H34ClN5O4Couleur et forme :SolidMasse moléculaire :576.092-Furoyl-LIGRLO-amide TFA
CAS :2-Furoyl-LIGRLO-amide TFA is a potent and selective agonist of the proteinase-activated receptor 2 (PAR2), exhibiting a pD2 value of 7.0 [1] [2].Formule :C38H64F3N11O10Couleur et forme :SolidMasse moléculaire :891.98YM543 free base
CAS :"YM543 is an effective, oral SGLT2 inhibitor that lowers blood glucose, useful for diabetes research."Formule :C23H24O6Couleur et forme :SolidMasse moléculaire :396.43BAY 73-1449
CAS :BAY 73-1449 is a selective and potent antagonist of the prostacyclin receptor(IC50<0.1 nM).Formule :C26H23N3O3Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :425.48Ref: TM-T26745
1mg42,00€5mg86,00€1mL*10mM (DMSO)88,00€10mg129,00€25mg215,00€50mg309,00€100mg411,00€200mg553,00€MK 0893
CAS :MK 0893 is a potent and selective Glucagon Receptor (GR) antagonist competitive, reversible cAMP activity, which attenuates blood glucose elevation.Formule :C32H27Cl2N3O4Degré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :588.48DS-1558
CAS :DS-1558 is a potent and orally available GPR40 agonist.DS-1558 was found to have potent glucose lowering effects during an oral glucose tolerance test in ZDFFormule :C21H21F3O4Couleur et forme :SolidMasse moléculaire :394.38[D-Ala6]-LH-RH
CAS :[D-Ala6]-LH-RH, a Luteinizing-hormone-releasing hormone (LHRH) analogue, functions as a gonadotropin-releasing hormone (GnRH) receptor agonist [1].Formule :C56H77N17O13Couleur et forme :SolidMasse moléculaire :1196.32Gestonorone Capronate
CAS :Gestonorone Capronate is a progesterone used in benign prostatic hyperplasia and endometrial cancer studies.Formule :C26H38O4Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :414.58Ref: TM-T13703
1mg138,00€5mg303,00€1mL*10mM (DMSO)343,00€10mg447,00€25mg713,00€50mg1.018,00€100mg1.369,00€PD-140548
CAS :PD-140548 is a potent, CCKA receptor-selective antagonist.Formule :C33H39N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :557.68S1P5 receptor agonist-1
CAS :S1P5 Receptor Agonist-1 (example 6) is a highly potent and selective agonist for the S1P5 receptor, exhibiting an EC50 value of 20 nM.Formule :C20H24F3NO3Couleur et forme :SolidMasse moléculaire :383.4Ubrogepant
CAS :Ubrogepant (MK-1602) is an antagonist of calcitonin gene-related peptide receptor that can be used in the acute treatment of migraine studies.Formule :C29H26F3N5O3Degré de pureté :99.452% - 99.78%Couleur et forme :SolidMasse moléculaire :549.54Ref: TM-T17194
1mg144,00€5mg358,00€1mL*10mM (DMSO)432,00€10mg565,00€25mg880,00€50mg1.161,00€100mg1.594,00€AGN-191129
CAS :AGN-191129 (PGF2α-OMe) is a PGF2α analog with C-1 carboxyl replaced by O-methyl; it lowers eye pressure, but its receptors are unclear.Formule :C21H38O4Couleur et forme :SolidMasse moléculaire :354.52BIM-23056 TFA
CAS :BIM 23056 TFA, a potent linear octapeptide antagonist of sst3 and sst5 somatostatin receptors, exhibits inhibition constants (K_i) of 10.8 for sst3 and 5.7 forFormule :C73H82F3N11O11Couleur et forme :SolidMasse moléculaire :1346.49Dihydrexidine
CAS :Dihydrexidine is a full efficacy D1-like dopamine receptor (D1/D5) agonist (IC50: 10 nM for D1 receptor). It also shows potent antiparkinsonian activity.Formule :C17H17NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :267.32(+)-Dihydrexidine hydrochloride
CAS :(+)-Dihydrexidine hydrochloride is an agonist of dopamine D1 receptor(EC50 of 72± 21 nM).Formule :C17H18ClNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :303.78Isopropyl 5-(Diphenylphosphoryl)pentanoate
CAS :Latanoprost, the isopropyl ester of 17-phenyl-13,14-dihydro prostaglandin F2α, serves as a prodrug for the free acid form, a potent FP receptor agonist in the eye. Isopropyl 5-(diphenylphosphoryl)pentanoate may exist as a potential trace impurity in commercial latanoprost preparations.Formule :C20H25O3PCouleur et forme :SolidMasse moléculaire :344.4γ-Linolenoyl monoethanolamide
CAS :γ-Linolenoyl monoethanolamide, a fatty N-acyl ethanolamine, acts as an endocannabinoid [1] [2].Formule :C20H35NO2Couleur et forme :SolidMasse moléculaire :321.5052,3-dinor Prostaglandin E1
CAS :Prostaglandin E1 (PGE1), though not predominantly found in nature, plays a significant role in clinical treatments, addressing conditions such as peripheral occlusive vascular disease, erectile dysfunction, and neonatal cardiology issues. The metabolism of PGE1 primarily begins with the oxidation at C-15, producing 13,14-dihydro-15-keto PGE1 as its major metabolite. Alternatively, inhibiting this pathway or overwhelming it with too much PGE1 could potentially enhance the production of 2,3-dinor metabolites, like 2,3-dinor PGE1, though their biological activities remain unreported. Cayman Chemical stands out as a prominent provider of prostaglandins and their metabolites, uniquely manufacturing 2,3-dinor PGE1.Formule :C18H30O5Couleur et forme :SolidMasse moléculaire :326.4BAY 60-2770
CAS :BAY 60-2770: oral sGC activator, NO-independent, antifibrotic, boosts sGC activity.Formule :C35H33F4NO5Couleur et forme :SolidMasse moléculaire :623.63RXFP1 receptor agonist-6
CAS :RXFP1 receptor agonist-6 (Example 7) serves as an agonist for the RXFP1 receptor and effectively suppresses cAMP production in HEK293 cells that stably expressFormule :C38H32F5N3O7Couleur et forme :SolidMasse moléculaire :737.67LM-1484
CAS :LM-1484 displays a higher affinity for 3H-LTC4 sites and is an antagonist of CysLT1 receptor.Formule :C28H24N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.52H3 receptor antagonist 1
CAS :H3 receptor antagonist 1 is used in the study of neurological diseases, histamine H3 receptor antagonist.Formule :C20H28F2N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :350.45Prostaglandin E2-1-glyceryl ester
CAS :Prostaglandin E2-1-glyceryl ester, a member of the Prostaglandin Glycerol Ester family, serves as an endocannabinoid ligand targeting the CB1 receptor. This compound triggers a swift and transient surge in intracellular free calcium levels [1] [2].Formule :C23H38O7Couleur et forme :SolidMasse moléculaire :426.55SUCNR1-IN-2
CAS :SUCNR1-IN-2 (Statement 35) is an effective SUCNR1 inhibitor for studying neurodegenerative diseases.Formule :C17H13F3N2O6Couleur et forme :SolidMasse moléculaire :398.29RU-SKI 43
CAS :RU-SKI 43: Potent, selective Hhat inhibitor, IC50 850 nM. Anticancer; potential lung adenocarcinoma treatment. Inhibits Gli-1, Akt, mTOR pathways.Formule :C22H30N2O2SDegré de pureté :99.85% - 99.92%Couleur et forme :SolidMasse moléculaire :386.55Prostaglandin K2
CAS :Prostaglandin K2 (PGK2), a 9,11-diketone derivative, results from PGE2 or PGD2 oxidation. Its biological presence remains speculative; however, it demonstrates resistance to in vitro metabolism by 15-hydroxy PGDH.Formule :C20H30O5Couleur et forme :SolidMasse moléculaire :350.455L 691678
CAS :L 691678 is a potent leukotriene biosynthesis inhibitor.Formule :C36H30IN5O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :771.63Quinpirole dihydrochloride
CAS :Quinpirole dihydrochloride is an agonist of the D2-like dopamine receptor.Formule :C13H23Cl2N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :292.25PSB-SB1202
CAS :PSB-SB1202 (Compound 21a), a phenyl coumarin compound, acts as a CB1/CB2 agonist. It demonstrates EC50 values of 56 and 14 nM and K i values of 32 and 49 nM for CB1 and CB2 receptors, respectively [1].Formule :C23H26O4Couleur et forme :SolidMasse moléculaire :366.45L-772,405
CAS :L-772,405 is a highly selective agonists of h5-HT(1D) receptor.Formule :C26H31FN6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :462.56Celiprolol hydrochloride
CAS :Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity.Formule :C20H33N3O4·HClCouleur et forme :White Crystalline SolidMasse moléculaire :415.96TP0438836
CAS :TP0438836: potent SGLT1 inhibitor, low absorption, for type 2 diabetes; IC50: 28nM (hSGLT1), 7nM (hSGLT2).Formule :C27H38N2O10Couleur et forme :SolidMasse moléculaire :550.6RO5527239
CAS :RO5527239 is a potent, orally available GPBAR1 agonist agent.Formule :C28H31N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :457.56Tarazepide
CAS :Tarazepide is a potent and specific antagonist of CCK-A receptor.Formule :C28H24N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :448.52CGS 21680
CAS :CGS 21680 is a chemical compound that acts as a selective agonist for both adenosine and its A2A receptor, demonstrating a binding affinity (K i) of 27 nM.Formule :C23H29N7O6Couleur et forme :SolidMasse moléculaire :499.52Pronetalol
CAS :Pronethalol ((±)-Pronethalol), a non-selective β-adrenergic antagonist, effectively inhibits Sox2 expression and offers protection against Digitalis-induced ventricular arrhythmias. Additionally, it can reverse such arrhythmias and limit the development of cerebral arteriovenous malformations (AVMs) [1] [2].Formule :C15H19NOCouleur et forme :SolidMasse moléculaire :229.32DU-125530
CAS :DU-125530 is a 5-HT1A receptor antagonist.Formule :C23H26ClN3O5SCouleur et forme :SolidMasse moléculaire :491.99PF-04634817 succinate
CAS :PF-0463481 succinate is a potent and orally active dual antagonist of CCR2/CCR5 with comparable human and rodent CCR2 potency with IC50 of 20.8 nM.Formule :C29H42F3N5O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :629.67CB2R-IN-1
CAS :CB2R-IN-1 is a potent inverse agonist of the cannabinoid CB2 receptor (Ki: 0.9 nM).Formule :C23H27F3N4O6S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :608.67(2S,3S)-E1R
CAS :(2R,3R)-E1R is a sigma-1 receptor modulator for cognitive/memory disorder treatment.Formule :C13H16N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :232.28TASP0412098
CAS :TASP0412098 is a potent, selective CRTH2 antagonist with oral activity.Formule :C27H23ClN2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.94RXFP1 receptor agonist-8
CAS :Example 2 (RXFP1 receptor agonist-8) is a potent RXFP1 receptor agonist that suppresses cAMP production in HEK293 cells expressing human RXFP1, exhibiting anFormule :C40H36F5N3O7Couleur et forme :SolidMasse moléculaire :765.72SKF 81297 hydrobromide
CAS :SKF 81297 hydrobromide, a selective agonist of the dopamine D1-like receptor，exhibits central activity and is widely used to study the neuromodulatory effects.Formule :C16H17BrClNO2Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :370.67Lidamidine
CAS :Lidamidine (Lidamidinum) is an effective antidiarrheal agent that inhibits intestinal secretion, reduces intestinal transit, and inhibits smooth muscleFormule :C11H16N4ODegré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :220.27Ref: TM-T25719
1mg115,00€2mg162,00€5mg249,00€10mg369,00€25mg562,00€50mg787,00€100mg1.054,00€200mg1.406,00€Bufuralol
CAS :Bufuralol (Ro 3-4787) is a 尾-adrenergic receptor blocker with a certain degree of sympathomimetic effects and can be used to study cardiovascular diseases.Formule :C16H23NO2Degré de pureté :98.26%Couleur et forme :SolidMasse moléculaire :261.36SLIGRL-NH2 TFA
CAS :SLIGRL-NH2 TFA, also known as Protease-Activated Receptor-2 Activating Peptide TFA, is a Protease-Activated Receptor-2 (PAR-2) agonist [1].Formule :C31H57F3N10O9Couleur et forme :SolidMasse moléculaire :770.84Thromboxane A2
CAS :Thromboxane A2: unstable, leads to thromboxane B2, induces platelet aggregation, causes vasoconstriction.Formule :C20H32O5Couleur et forme :SolidMasse moléculaire :352.47AZD2423
CAS :AZD2423 is a potent, selective, orally bioavailable, and non-competitive CCR2 chemokine receptor negative allosteric modulator and it has an IC50 of 1.2 nM forFormule :C20H29ClFN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :425.93CI-949
CAS :CI-949 inhibits LTC4/D4, histamine, TXB2 release (IC50: 0.5, 11.4, 0.1 μM).Formule :C20H20N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :392.41Ro-70-0004
CAS :Ro-70-0004 is a selective antagonist of alpha1A-adrenoceptor.Formule :C20H24F4N4O3Couleur et forme :SolidMasse moléculaire :444.42(2R,3S)-E1R
CAS :(2R,3S)-E1R, an enantiomer of E1R, is a sigma-1 receptor modulator for treating cognitive disorders.Formule :C13H16N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :232.28
