GPCR/G-Protéine
Les inhibiteurs des GPCR/protéines G sont des composés qui ciblent les récepteurs couplés aux protéines G (GPCR) et les protéines G associées, qui jouent un rôle crucial dans la transmission des signaux de l'extérieur vers l'intérieur des cellules. Ces inhibiteurs sont essentiels pour étudier les voies de signalisation médiées par les GPCR, impliquées dans de nombreux processus physiologiques, y compris la perception sensorielle, la réponse immunitaire et la neurotransmission. Les inhibiteurs des GPCR sont également importants dans le développement de médicaments, car de nombreux agents thérapeutiques ciblent ces récepteurs. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de GPCR/protéines G de haute qualité pour soutenir vos recherches en pharmacologie, biologie cellulaire et domaines connexes.
Sous-catégories appartenant à la catégorie "GPCR/G-Protéine"
- récepteur 5-HT(1.025 produits)
- Récepteur d'adénosine(249 produits)
- Récepteur adrénergique(3.023 produits)
- Récepteur de la bombésine(35 produits)
- Récepteur de la bradykinine(61 produits)
- CXCR(158 produits)
- CaSR(34 produits)
- Récepteur cannabinoïde(217 produits)
- Cholécystokinine(1 produits)
- Récepteur de la dopamine(445 produits)
- Récepteur de l'endothéline(86 produits)
- Récepteur GNRH(84 produits)
- GPCR19(33 produits)
- GRK(33 produits)
- GTPase(23 produits)
- Récepteur du glucagon(194 produits)
- Hérisson/Smoothened(49 produits)
- Récepteur de l'histamine(385 produits)
- Récepteur LPA(21 produits)
- Récepteur de la mélatonine(26 produits)
- Récepteur OX(41 produits)
- Récepteur opioïde(327 produits)
- PAFR(14 produits)
- PKA(60 produits)
- Récepteur S1P(18 produits)
- SGLT(31 produits)
- Récepteur Sigma(46 produits)
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5986 produits trouvés pour "GPCR/G-Protéine"
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CCG258208
CAS :GRKs-IN-1 has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50: 130 nM) and GRK5 (IC50: 7.1 μM).Formule :C24H25FN4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :452.48A3AR antagonist 5
CAS :A3AR antagonist 5 (Compound 16) acts as a selective antagonist for the human adenosine A3 receptor (human adenosine A3 receptor), with an affinity expressed as a pC value of 4.542 μM.Formule :C18H16N2O2SCouleur et forme :SolidMasse moléculaire :324.40AA 497 (Free Base)
CAS :AA 497, a beta-2 agonist, causes relaxation and suppresses Ca spike frequency.Formule :C14H21NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :251.32CBR Agonist-1
CBR Agonist-1 targets CB1R and CB2R with Ki of 0.18 μM and 1.22 μM, useful for studying cannabinoid-related diseases.Formule :C27H27FN4OCouleur et forme :SolidMasse moléculaire :442.53AAZ-A 154 hydrobromide
CAS :AAZ-A 154 hydrobromide is a selective, competitive, non-hallucinogenic 5-HT2AR antagonist. It promotes neuronal growth in rodents and yields enduring beneficial behavioral effects.Formule :C14H21BrN2OCouleur et forme :SolidMasse moléculaire :313.23Dersimelagon phosphate
CAS :Dersimelagon phosphate: MC1R agonist, boosts melanin, enhances light tolerance in EPP/XLP without sun.Formule :C36H48F4N3O9PCouleur et forme :SolidMasse moléculaire :773.75SEP-363856 mesylate
CAS :SEP-363856 (SEP-856) mesylate is an orally active compound that acts as an agonist for both TAAR1 and 5-HT1A receptors. This compound exhibits antipsychotic activity in the central nervous system and has potential for the study of schizophrenia.Formule :C10H17NO4S2Couleur et forme :SolidMasse moléculaire :279.38UK-432097
CAS :UK 432097 is an adenosine A2A agonist.Formule :C40H47N11O6Couleur et forme :SolidMasse moléculaire :777.87AAZ-A 154 hydrochloride
CAS :AAZ-A 154 hydrochloride is a selective, competitive, non-hallucinogenic antagonist of 5-HT2AR. It promotes neuronal growth in rodents and results in enduring beneficial behavioral effects.Formule :C14H21ClN2OCouleur et forme :SolidMasse moléculaire :268.78Mesulergine hydrochloride
CAS :5-HT2A and 2C receptor antagonistFormule :C18H27ClN4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :398.95Atumelnant
CAS :Atumelnant (CRN04894) is an MC2R antagonist used in the study of congenital adrenocortical hyperplasia (CAH) and Cushing's disease (CD).Formule :C33H42F3N5O3Degré de pureté :98.41%Couleur et forme :SolidMasse moléculaire :613.71PD 135158
CAS :PD 135158 is a CCK2 receptor antagonist.Formule :C42H61N5O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :811.96L 156903
CAS :L 156903 is a bioactive chemical. It also inhibits the binding of neurotensin to brain tissue.Formule :C35H41N7O5SCouleur et forme :SolidMasse moléculaire :671.81PDE4B/7A-IN-1
CAS :5-HT1A antagonist; Ki=8nM, Kb=0.04nM. PDE4B IC50=80.4μM; PDE7A IC50=151.3μM. Good biofilm penetration, stable, anticognitive, antidepressant.Formule :C25H35N3O3Couleur et forme :SolidMasse moléculaire :425.56U91356
CAS :U91356 is an agonist of the dopamine receptors.Formule :C13H17N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :231.29BI-685509
CAS :BI-685509: potent, oral sGC activator, boosts cGMP, enhances NO pathways, for CKD/DKD research.Formule :C34H38N4O5Couleur et forme :SolidMasse moléculaire :582.69VGD071
CAS :VGD071, a compound that targets sortilin, presents a promising avenue for forthcoming research utilizing mouse models of breast cancer.Formule :C32H41N3O4S2Couleur et forme :SolidMasse moléculaire :595.82AFP-07
CAS :AFP-07 is a highly selective and potent agonist. It was used for the prostacyclin receptor.Formule :C22H29F2NaO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.45Aplaviroc hydrochloride
CAS :Aplaviroc, a potent CCR5 inhibitor, binds selectively, blocking HIV entry and specific monoclonal antibody attachment in vitro.Formule :C33H44ClN3O6Couleur et forme :SolidMasse moléculaire :614.17Metrazoline
CAS :Metrazoline (o-Methyl-tracizoline) acts as a ligand for adrenergic receptors (low affinity) and imidazoline I2 receptors.
Formule :C14H16N2O4Couleur et forme :SolidMasse moléculaire :276.288U75302
CAS :U75302 is an antagonist of thymosin beta-4 (TB4) receptor with a Ki value of 159 nM on guinea pig lung membranes.Formule :C22H35NO3Degré de pureté :98%Couleur et forme :Light Yellow OilMasse moléculaire :361.52COX-2-IN-6
CAS :COX-2-IN-6: Potent, selective COX-2 inhibitor; oral; IC50 0.84μM, Ki 69nM; blocks PGE2 synthesis; prevents colorectal cancer.Formule :C20H27NO6SDegré de pureté :99.29% - 99.32%Couleur et forme :SoildMasse moléculaire :409.55-HT1A modulator 4
CAS :5-HT1A modulator 4 (Compound 1) is a ligand for the 5-HT receptor, with Ki values of 2.18 μM for 5-HT1A and 19.7 μM for 5-HT2A.Formule :C9H14N4Couleur et forme :SolidMasse moléculaire :178.234PAR4 antagonist 3
CAS :PAR4 antagonist3 (Compound 36) is a selective antagonist of protease-activated receptor 4 (PAR4). It exhibits antiplatelet activity with an IC50 of 26.1 nM and enhances metabolic stability in human liver microsomes, with a half-life (T1/2) of 97.6 minutes.Formule :C22H16FN3O5SMasse moléculaire :453.44KAG-308
CAS :KAG-308: selective EP4 agonist; Ki: 2.57 nM, EC50: 17 nM; suppresses colitis, promotes mucosal healing, inhibits TNF-α.Formule :C24H30F2N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :460.52SB 224289
CAS :SB 224289: selective 5-HT1B antagonist, pKi 8.2, 60x selectivity, effective orally.Formule :C32H32N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :520.62N-methyl Leukotriene C4
CAS :N-methyl LTC4 is a stable synthetic analog of LTC4 and a selective CysLT2 agonist, useful in studying leukotriene pharmacology.Formule :C31H49N3O9SCouleur et forme :SolidMasse moléculaire :639.8EP4 receptor antagonist 2
CAS :EP4 receptor antagonist 2 (compound 2-13) is a potent agonist of the EP4 receptor (IC50: 7.8 nM) and has antitumour effects.Formule :C27H29N3O5Couleur et forme :SolidMasse moléculaire :475.54LK-732
CAS :LK-732 is a thrombin inhibitor with antithrombotic activity. It exhibits dose-dependent inhibition in models of hypercoagulability, with an IC50 value of 1.3 mg/kg. LK-732 is used in cardiovascular and cerebrovascular research.Formule :C25H29N5O3SCouleur et forme :SolidMasse moléculaire :479.59Lp(a)-IN-8
CAS :LPA2 antagonist 3 (compound 15) serves as an Lp(a) antagonist. Lp(a) is a pathogenic risk factor for atherosclerotic cardiovascular disease (ASCVD).Formule :C21H40Cl2N4O5Couleur et forme :SolidMasse moléculaire :499.472S1PR1 agonist 2
CAS :S1PR1 agonist 2 is potent for autoimmune research (from WO2021175225A1).Formule :C25H25N5O4Couleur et forme :SolidMasse moléculaire :459.50GRPR antagonist-2
GRPR antagonist-2 blocks GRPR, kills some cancer cells, effective on HGC-27 (IC50: 0.77 μM) & Pan02 (IC50: 2.5 μM).Formule :C28H32F3N5O4Couleur et forme :SolidMasse moléculaire :559.58LPA2 antagonist 5
CAS :LPA2 antagonist 5 (EX1) functions as an antagonist of LPA2, with an IC50 value of 4.05 nM.Formule :C17H17F3N2O5Couleur et forme :SolidMasse moléculaire :386.323Histamine H3 antagonist-1
CAS :Compound 10o, a histamine H3 antagonist-1, functions as both a histamine H3 antagonist and a serotonin reuptake inhibitor, making it useful for research in depression [1].
Formule :C24H28F3N3O2Couleur et forme :SolidMasse moléculaire :447.49MED 27
CAS :MED 27 is an inhibitor of thromboxane synthase and thromboxane A2 receptors. It effectively inhibits rat platelet aggregation at doses significantly lower than those required for acetylsalicylic acid.Formule :C24H25N5O5Couleur et forme :SolidMasse moléculaire :463.49hA3AR agonist 1
hA3AR agonist 1 is a potent human A 3 adenosine receptor (hA 3 AR) agonist (Ki = 2.40 nM) .Formule :C10H14N6OSCouleur et forme :SolidMasse moléculaire :266.32Dopamine D3 receptor antagonist-1
Dopamine D3 receptor antagonist-1 is a dopamine D3 receptor selective or multi-targeting ligand with a Ki value of 1.58 nM that has demonstrated therapeuticFormule :C31H35Cl2N3O3Couleur et forme :SolidMasse moléculaire :568.53Sitamaquine hydrochloride
CAS :Sitamaquine hydrochloride (WR 6026) is an orally active 8-aminoquinoline analog with antileishmanial activity. This compound inhibits mitochondrial complex II (succinate dehydrogenase) and is characterized by its lipophilic weak base properties. It rapidly accumulates in the acidic compartments of Leishmania parasites, predominantly localizing within the acidocalcisomes.Formule :C21H35Cl2N3OCouleur et forme :SolidMasse moléculaire :416.43Edonentan hydrate
CAS :Edonentan (BMS 207940) hydrate effectively blocks the endothelin A (ETA) receptor as a potent and selective antagonist, featuring a K i of 10 pM. It exhibits complete (100%) oral bioavailability in rats [1].Formule :C28H34N4O6SCouleur et forme :SolidMasse moléculaire :554.66HU-308
CAS :HU-308, a synthetic cannabinoid analogue, is a highly selective agonist of the CB2 receptor. It demonstrates an affinity for the CB2 receptor that is over 440 times greater than its affinity for the CB1 receptor, which are predominantly found in immune cells. This compound plays a crucial role in modulating the immunosuppressive effects of the endocannabinoid system (ECS). Additionally, HU-308 possesses anti-inflammatory and neuroprotective properties, and it regulates the function of microglia. Its potential applications include research into neuroinflammation and retinal diseases.
Formule :C27H42O3Couleur et forme :SolidMasse moléculaire :414.62Cendifensine
CAS :Cendifensine functions as a monoamine reuptake inhibitor, targeting the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).Formule :C14H17Cl2NOCouleur et forme :SolidMasse moléculaire :286.197AAZ-A 154 mesylate
CAS :AAZ-A 154 mesylate mesylate is a selective, competitive, and non-hallucinogenic antagonist of 5-HT2AR. It enhances neuronal growth in rodents and produces enduring beneficial behavioral effects.Formule :C15H24N2O4SCouleur et forme :SolidMasse moléculaire :328.43LPA5 antagonist 2
LPA5 antagonist 2, compound 65, water-soluble, reduces nociception, for inflammatory/neuropathic pain study.Formule :C26H25FN2O4SCouleur et forme :SolidMasse moléculaire :480.55CP-199330
CAS :CP-199330: non-toxic alternative to Zafirlukast & Pranlukast, blocks cysteyl LT1 receptors.Formule :C28H24ClF3N2O6SCouleur et forme :SolidMasse moléculaire :609.01BRD50837
CAS :BRD50837 is a potent and selective inhibitor of Sonic Hedgehog (Shh).Formule :C26H32ClN3O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :550.07CI-624
CAS :CI-624 reduces the secretion and output of hydrogen ions, sodium ions, potassium ions, and pepsin. This compound may be utilized in research focusing on cancer and autoimmune diseases.Formule :C8H8N2SCouleur et forme :SolidMasse moléculaire :164.228AFP-07 free acid
CAS :AFP 07 free acid is a 7,7-difluoroprostacyclin derivative. It also acts as a selective and highly potent agonist for the IP receptor.Formule :C22H30F2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :412.47(R)-BAY-899
(R)-BAY-899: R-isomer, selective LH-R antagonist, effective on hLH (IC50: 185 nM) and rLH (IC50: 46 nM), orally active.Formule :C25H19F2N5O2Couleur et forme :SolidMasse moléculaire :459.45CP-865569
CAS :CP-865569 is a CCR1 antagonist useful in the research of inflammatory and autoimmune diseases, including conditions such as rheumatoid arthritis and multiple sclerosis.Formule :C22H26ClFN2O5SCouleur et forme :SolidMasse moléculaire :484.969Substituted piperidines-1
CAS :Substituted piperidines-1 can promote the release of growth hormone in humans and animals.Formule :C29H39N7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :517.67Kendomycin
CAS :Kendomycin is a proteasome inhibitor and endothelin receptor antagonist. It induces apoptosis in lymphoma.Formule :C29H42O6Couleur et forme :SolidMasse moléculaire :486.64Abarelix acetate
CAS :Abarelix acetate: synthetic GnRHR antagonist, spikes histamine, lowers LH and testosterone temporarily, used in advanced prostate cancer.Formule :C72H95ClN14O14·xC2H4O2Couleur et forme :SolidMasse moléculaire :1476.14Diosuxentan
CAS :Diosuxentan is an inhibitor of ETA and is utilized in research pertaining to cardiovascular, renal, and neuronal inflammatory diseases.Formule :C20H21BrN6O7SCouleur et forme :SolidMasse moléculaire :569.39MK-3207 Hydrochloride
CAS :MK-3207 Hydrochloride (MK-3207 HCl) is a potent CGRP receptor antagonist with IC50 and Kiof 0.12 nM and 0.022 nM, highly selective versus human AM1, AM2, CTR, and AMY3. Phase 2.Formule :C31H30ClF2N5O3Degré de pureté :98.19%Couleur et forme :SolidMasse moléculaire :594.05SB 243213 dihydrochloride
CAS :SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 forFormule :C22H21Cl2F3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :501.33(E/Z)-Ozagrel sodium
CAS :(E/Z)-Ozagrel (sodium) [(E/Z)-OKY-046 (sodium)] is a mixture of the EZ isomers of Ozagrel (sodium). It acts as a thromboxane A2 (TXA2) synthase inhibitor. As an antiplatelet agent, Ozagrel (sodium) selectively inhibits human platelet aggregation, with an IC50 of 53.12 μM.Formule :C13H11N2NaO2Couleur et forme :SolidMasse moléculaire :250.228L-796778 acetate
CAS :L-796778 acetate is a selective sst3 receptor agonist. In CHO-K1 cells expressing hsst3 receptors, it acts as a partial agonist that inhibits Forskolin-induced cAMP production, with an IC50 value of 18 nM. Additionally, L-796778 acetate exhibits anticonvulsant properties.Formule :C31H44N6O9Couleur et forme :SolidMasse moléculaire :644.716Sigma-1 receptor antagonist 6
CAS :Sigma-1 receptor antagonist 6 (Compound 12), a σ1R antagonist, demonstrates significant antiallodynic effects by targeting the Sigma-1 receptor (σ1R). This compound is effective in animal models for neuropathic pain, particularly for reducing mechanical allodynia caused by paclitaxel.Formule :C32H34N6Couleur et forme :SolidMasse moléculaire :502.65AAZ-A 154
CAS :AAZ-A 154 is a selective, competitive, and non-hallucinogenic antagonist of the 5-HT2AR. It promotes neuronal growth in rodents and results in lasting beneficial behavioral effects.Formule :C14H20N2OCouleur et forme :SolidMasse moléculaire :232.32Serlopitant
CAS :Serlopitant is a selective antagonist of Neurokinin-1 (NK-1) receptor.Formule :C29H28F7NO2Couleur et forme :SolidMasse moléculaire :555.5325C-NBF hydrochloride
CAS :25C-NBF hydrochloride is an agonist of 5-HT receptors, specifically activating 5-HT2A and 5-HT2C receptors, with an EC50 of approximately 0.3 μM.Formule :C17H20Cl2FNO2Masse moléculaire :360.251Dopamine D3 receptor ligand-1
Dopamine D 3 receptor ligand is a potent, selective, high-affinity dopamine D3 receptor ligand that is 89 times more selective for D3 (Ki: 8 nM) than D2 (Ki:Formule :C27H29N5OCouleur et forme :SolidMasse moléculaire :439.55APJ receptor agonist 8
CAS :APJ receptor agonist 8 is a small molecule agonist of the APJ receptor, enhancing load-independent cardiac contractility in isolated perfused rat hearts.
Formule :C24H27N7O5SDegré de pureté :98.31% - 99.60%Couleur et forme :SolidMasse moléculaire :525.58SSTR5 antagonist 2 hydrochloride
SSTR5 antagonist 2 hydrochloride: potent, oral SSTR5 blocker with potential in type 2 diabetes research.Formule :C32H36ClFN2O5Couleur et forme :SolidMasse moléculaire :583.09Nocloprost
CAS :Nocloprost (SH 475) is a prostaglandin E2 (PGE2) analog, an EP1 and EP3 receptor agonist with local gastric protection and ulcer healing effects.Formule :C22H37ClO4Couleur et forme :SolidMasse moléculaire :400.98AAZ-A 154 benzoate
CAS :AAZ-A 154 benzoate is a selective, competitive, and non-hallucinogenic 5-HT2AR antagonist. This compound facilitates neuronal growth in rodents and produces lasting beneficial behavioral effects.Formule :C21H26N2O3Couleur et forme :SolidMasse moléculaire :354.44FDU-PB-22
CAS :FDU-PB-22, a novel synthetic cannabinoid, undergoes rapid metabolism in human liver microsomes (HLM) with a half-life of 12.4 minutes.Formule :C26H18FNO2Couleur et forme :SolidMasse moléculaire :395.43H3R antagonist 2
Compound 23: H3R antagonist with 170 nM Ki; inhibits AChE, BChE, hMAO B; IC50s: 180, 880, 775 nM; anti-pain, memory boost; crosses BBB. [1]Formule :C24H29NO3Couleur et forme :SolidMasse moléculaire :379.49Leukotriene F4
CAS :LTF4, made in vitro from LTE4 with enzymes, contracts vascular muscle weakly; potency is LTD4 > LTC4 > LTE4 >> LTF4.Formule :C28H44N2O8SCouleur et forme :SolidMasse moléculaire :568.72Protease-Activated Receptor-1 antagonist 3
PAR-1 antagonist 3: potent (IC50: 7 nM), binds hERG K+ channels (IC50: 9 μM).Formule :C30H34N4O3Couleur et forme :SolidMasse moléculaire :498.6214,15-dehydro Leukotriene B4
CAS :LTB4 is a leukocyte-activating fatty acid via 5-lipoxygenase. Two receptors, BLT1 and BLT2, bind it. 14,15-dehydro LTB4 is a stronger BLT1 antagonist.Formule :C20H30O4Couleur et forme :SolidMasse moléculaire :334.45CB2 receptor antagonist 1
CAS :Compound 29 is a potent, CB2-selective antagonist/reverse agonist. Derivatives 23 & 24 offer antinociception; 24 activates cannabinoid/TRPV1 receptors.Formule :C28H47NO3Couleur et forme :SolidMasse moléculaire :445.68RXFP1 receptor agonist-10
CAS :RXFP1 receptor agonist-10 (Compound 188) is an RXFP1 receptor agonist with an EC50 of 0.5 nM. It is useful for research into heart failure.Formule :C39H44F6N4O5Couleur et forme :SolidMasse moléculaire :762.78Quinagolide Free Base
CAS :Quinagolide Free Base is a non-ergot dopamine D(2)-agonist.Formule :C20H33N3O3SCouleur et forme :SolidMasse moléculaire :395.56K-14585
CAS :K-14585 blocks PAR(2), reduces NFkappaB activity, and IL-8 response, but alone can boost IL-8.Formule :C51H56Cl2N8O4Couleur et forme :SolidMasse moléculaire :915.95ATX inhibitor 27
CAS :ATX inhibitor 27 (Compound 31) is an ATX inhibitor. It demonstrates IC50 values of 13 nM against human autotaxin (hATX) and 23 nM against lysophosphatidylcholine (LPC). By inhibiting the ATX enzyme, ATX inhibitor 27 reduces LPA levels in the body. This compound is applicable in research related to ATX-LPA-associated conditions such as inflammation, neurodegenerative disorders, and cancer.Formule :C26H26ClN5O3Couleur et forme :SolidMasse moléculaire :491.97L-657926
CAS :L-657926 is a stereoselective antagonist of the thromboxane A2 (TxA2) receptor, composed of (-)-9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-1-yl acetic acid and (+)-9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-1-yl acetic acid. The IC50 values for the (-) and (+) configurations against TxA2 are 0.27 nM and 124 nM, respectively.Formule :C21H19ClFNO2Couleur et forme :SolidMasse moléculaire :371.832NK1 receptor antagonist 2
CAS :NK1 Receptor Antagonist 2, a compound targeting the NK1 receptor, holds potential for tinnitus and hearing loss research.Formule :C31H35F7N4O2Couleur et forme :SolidMasse moléculaire :628.62Fasitibant
CAS :Fasitibant is a potent and selective nonpeptide kinin B2 receptor antagonist.Formule :C36H49Cl2N6O6SCouleur et forme :SolidMasse moléculaire :764.78Sulamserod hydrochloride
CAS :Sulamserod hydrochloride is a 5-HT4 receptor antagonist. It is utilized in research related to gastrointestinal disorders.Formule :C19H29Cl2N3O5SCouleur et forme :SolidMasse moléculaire :482.42RTIOXA-43
CAS :RTIOXA-43 is an OX2R/OX1R (orexin receptor) dual agonist that increases wakefulnesand is commonly used in studies related to narcolepsy and neural signaling.Formule :C37H37N5O5SDegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :663.79Ref: TM-T87345
1mg210,00€5mg516,00€1mL*10mM (DMSO)754,00€10mg833,00€25mg1.607,00€50mg2.582,00€100mg3.492,00€WIN 66306
CAS :WIN 66306: Cyclic heptapeptide, blocks NK1/NK2 receptors, inhibits substance P-triggered contractions in guinea pig ileum.Formule :C41H52N8O9Couleur et forme :SolidMasse moléculaire :800.9MRGPRX2 modulator-3
CAS :MRGPRX2 modulator-3 (Compound 4-400) is a quinoline derivative and an MRGPRX2 regulator. It is utilized in the investigation of MRGPRX2-related conditions, including allergies, itching, pain, inflammation, and autoimmune diseases.Formule :C21H21ClF3N5OCouleur et forme :SolidMasse moléculaire :451.87GLP-1 receptor agonist 10
CAS :GLP-1 Receptor Agonist 10 (Compound 42), an agonist of the GLP receptor, reduces glucose excursions and inhibits food intake in mice. It is useful for research into type 2 diabetes (T2DM) and obesity [1].Formule :C30H28F4N6O5Couleur et forme :SolidMasse moléculaire :628.57Lisuride
CAS :Lisuride: an oral D2 dopamine agonist, ergot derivative, used in Parkinson's, migraine, and high prolactin research.Formule :C20H26N4OCouleur et forme :SolidMasse moléculaire :338.4516(R)-Iloprost
CAS :Iloprost, a potent prostacyclin analog, binds IP & EP1 receptors (Ki 11 nM), contains 16(S/R) isomers, and inhibits platelets (IC50 65 nM).Formule :C22H32O4Couleur et forme :SolidMasse moléculaire :360.49Beloxepin
CAS :Beloxepin is an oral dual selective inhibitor of serotonin and norepinephrine uptake.Formule :C19H21NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :295.38Burapitant
CAS :Burapitant (SSR 240600) is a novel non-peptide tachykinin neurokinin 1 (NK) receptor antagonist with anti-coke oven and antidepressant activity.
Formule :C31H35Cl2F6N3O3Degré de pureté :>99.99% - >99.99%Couleur et forme :SolidMasse moléculaire :682.52AM8936
AM8936: potent CB1 agonist, EC50 rCB1=8.6nM/hCB1=1.4nM, Ki rat CB1=0.55nM; potential for CNS, metabolic, pain, glaucoma research.Formule :C25H33NO3Couleur et forme :SolidMasse moléculaire :395.53BAY-899
CAS :BAY-899, oral LH-R antagonist, IC50: 185 nM (hLH), 46 nM (rLH), lowers sex hormones in vivo.Formule :C25H19F2N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.45A2A receptor antagonist 2
A2A receptor antagonist 2 is a highly selective and potent antagonist of the adenosine A2Areceptor (IC50: 8.3 nM).Formule :C25H28FN7O3Couleur et forme :SolidMasse moléculaire :493.53Aplaviroc
CAS :Aplaviroc (AK 602), a SDP derivative, is a CCR5 antagonist. With IC50s of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW.Formule :C33H43N3O6Degré de pureté :97.98% - 98.26%Couleur et forme :SolidMasse moléculaire :577.71Iralukast (CGP 45715A)
CAS :Iralukast is a cysteinyl-leukotriene antagonist (CysLT) with a pKi of 7.8 for CysLT1.Formule :C38H37F3O8SCouleur et forme :SolidMasse moléculaire :710.76LK 11
CAS :LK-11, an alkaloid derivative, inhibits the passive uptake of norepinephrine (NA) by synaptic vesicles in the thalamus, similarly to cocaine.Formule :C15H26N2O3Couleur et forme :SolidMasse moléculaire :282.38AL 6598
CAS :AL 6598, a prodrug of PGD2 agonist AL 6556, reduces IOP by 53% at 1μg twice daily in monkeys; binds DP receptors with Ki of 3.2μM.Formule :C23H39ClO5Couleur et forme :SolidMasse moléculaire :431.01NPR-C activator 1
CAS :NPR-C activator 1 is an activator of the natriuretic peptide receptor C (NPR-C), which can be used to study cardiovascular diseases.Formule :C18H24N6O3Degré de pureté :98.74%Couleur et forme :SolidMasse moléculaire :372.42CCR5 antagonist 1
CAS :CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2. It can inhibit HIV replication.Formule :C39H46ClF2N5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :738.33BI 639667
CAS :BI 639667, an azaindazole-class compound, potently inhibits CCR1 (IC50=1.8 nM in calcium flux assays).Formule :C22H18FN5O3SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :451.47CP-481715
CAS :CP 481715 is an effective selective CCR1 antagonist with potential therapeutic significance for inflammatory diseases.Formule :C26H31FN4O4Couleur et forme :SolidMasse moléculaire :482.55Cicaprost
CAS :Cicaprost (ZK 96480) is an IP agonist with artery relaxing effects; EC50 is 5.8 nM.Formule :C22H30O5Couleur et forme :SolidMasse moléculaire :374.47
