GPCR/G-Protéine
Les inhibiteurs des GPCR/protéines G sont des composés qui ciblent les récepteurs couplés aux protéines G (GPCR) et les protéines G associées, qui jouent un rôle crucial dans la transmission des signaux de l'extérieur vers l'intérieur des cellules. Ces inhibiteurs sont essentiels pour étudier les voies de signalisation médiées par les GPCR, impliquées dans de nombreux processus physiologiques, y compris la perception sensorielle, la réponse immunitaire et la neurotransmission. Les inhibiteurs des GPCR sont également importants dans le développement de médicaments, car de nombreux agents thérapeutiques ciblent ces récepteurs. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de GPCR/protéines G de haute qualité pour soutenir vos recherches en pharmacologie, biologie cellulaire et domaines connexes.
Sous-catégories appartenant à la catégorie "GPCR/G-Protéine"
- récepteur 5-HT(1.025 produits)
- Récepteur d'adénosine(248 produits)
- Récepteur adrénergique(2.998 produits)
- Récepteur de la bombésine(35 produits)
- Récepteur de la bradykinine(61 produits)
- CXCR(154 produits)
- CaSR(34 produits)
- Récepteur cannabinoïde(216 produits)
- Cholécystokinine(1 produits)
- Récepteur de la dopamine(445 produits)
- Récepteur de l'endothéline(86 produits)
- Récepteur GNRH(84 produits)
- GPCR19(33 produits)
- GRK(33 produits)
- GTPase(23 produits)
- Récepteur du glucagon(191 produits)
- Hérisson/Smoothened(49 produits)
- Récepteur de l'histamine(385 produits)
- Récepteur LPA(21 produits)
- Récepteur de la mélatonine(26 produits)
- Récepteur OX(40 produits)
- Récepteur opioïde(325 produits)
- PAFR(14 produits)
- PKA(60 produits)
- Récepteur S1P(17 produits)
- SGLT(31 produits)
- Récepteur Sigma(46 produits)
Affichez 19 plus de sous-catégories
5960 produits trouvés pour "GPCR/G-Protéine"
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GEP44
GEP44 is a peptide-biased triple agonist targeting the glucagon-like peptide-1 receptor (GLP-1R), neuropeptide Y1 receptor (Y1-R), and neuropeptide Y2 receptor (Y2-R). It induces GLP-1R-dependent insulin secretion in rat and human islets by offsetting the actions of Y1-R and GLP-1R agonism, controlled by Y1-R antagonists. Additionally, GEP44 enhances glucose uptake in muscle tissue through Y1-R mediation independent of insulin and significantly reduces food intake and body weight in diet-induced obese rat models. GEP44 is utilized in studies related to obesity and type 2 diabetes.Couleur et forme :Odour SolidJmv 176
CAS :Jmv 176 is a CCK agonist when first given and becomes a cholecystokinin antagonist after 3-4 hours.Formule :C53H70N8O15SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1091.24[Nle11]-Substance P
CAS :'[Nle11]-Substance P is a gut and brain peptide, resisting methionine oxidation and causing excitatory neural effects.'
Formule :C64H100N18O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1329.59MDL 19301
CAS :MDL 19301 is a nonsteroidal, anti-inflammatory agent.Formule :C15H21NS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :279.46JNJ-39933673
CAS :JNJ-39933673 is a bio-active chemical.Formule :C48H54F2N2O11Couleur et forme :SolidMasse moléculaire :872.96JMV-1645
CAS :JMV-1645 is an effective and selective B(1) bradykinin receptor antagonist.Formule :C49H69N13O12SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1064.23(S)-Azelastine hydrochloride
CAS :(S)-Azelastine HCl, an antihistamine, reduces H1R, M1R, M3R levels and inhibits HNEpC growth.Formule :C22H25Cl2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :418.36Nolomirole
CAS :Nolomirole is a dopamine receptor agonist that reduces symptoms of congestive heart failure caused by monoclinine.Formule :C19H27NO4Couleur et forme :SolidMasse moléculaire :333.42N-desmethyl Zolmitriptan
CAS :DZT, an active metabolite of zolmitriptan, agonizes 5-HT1B/D receptors; contracts human cerebral arteries (EC50=100nM).Formule :C15H19N3O2Couleur et forme :SolidMasse moléculaire :273.33EP4-IN-1
CAS :EP4-IN-1: Potent EP4 receptor inhibitor with anti-tumor, anti-inflammatory, and analgesic properties.Formule :C27H24N2O4Degré de pureté :99.94%Couleur et forme :SoildMasse moléculaire :440.498-iso Prostaglandin E1
CAS :8-iso Prostaglandin E1 causes spasm in the pulmonary veins of dogs and also acts as a vasodilator.
Formule :C20H34O5Couleur et forme :Light Yellow Crystalline SolidMasse moléculaire :354.48SB-206606
CAS :SB-206606 is a novel, highly specific radioactive ligand for the β3-adrenergic receptor.
Formule :C19H22ClNO4Couleur et forme :SolidMasse moléculaire :363.83Denikitug
Denikitug is a chimeric antibody of the IgG1κ type that targets CCR8, with its corresponding isotype control being HumanIgG1kappa, Isotype Control.Couleur et forme :Odour LiquidPlozalizumab
CAS :Plozalizumab (MLN-1202) is a humanized selective and potent anti-CCR2 antibody.Plozalizumab has antitumor activity.Plozalizumab is used in the study of
Degré de pureté :96.4%Couleur et forme :LiquidMasse moléculaire :146.02 kDaCinanserin hydrochloride
CAS :Cinanserin hydrochloride (SQ 10643) is a 5-HT2 receptor blocker (Ki: 41 nM) and SARS-CoV 3C-like protease inhibitor.Formule :C20H25ClN2OSDegré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :376.94Nebokitug
Nebokitug is a humanized IgG1κ antibody targeting CCL24, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Couleur et forme :Odour LiquidΔ9-THCH
CAS :Δ9-THCH, a phytocannabinoid analytical reference standard, is present in a Cannabis variety cultivated for medicinal use. In the United States, it is classified as a Schedule I compound. This product is designated for research and forensic applications.Formule :C22H32O2Couleur et forme :SolidMasse moléculaire :328.49S1H
S1H is an analog of human growth hormone (hGH) and acts as an antagonist to the human growth hormone receptor (hGHR). It inhibits the interaction between hGH and hGHR and prevents the phosphorylation of STAT5 in cells treated with hGH.Formule :C94H141N23O27Masse moléculaire :2024.03673JMV 449
CAS :Potent neurotensin agonist; IC50=0.15 nM, EC50=1.9 nM. Causes hypothermia, neuroprotection, analgesia in mice.Formule :C38H66N8O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :746.96CI-988 hemihydrate
CI-988 hemihydrate (PD134308) is a potent and selective orally active CCK2R (cholecystokinin 2 receptor) antagonist, with an IC50 of 1.7 nM for mouse cortical CCK2. It is over 1600 times more selective for CCK2 than for CCK1 receptors. CI-988 hemihydrate exhibits anxiolytic and antitumor properties.Formule :C35H42N4O6H2OMasse moléculaire :632.321BPP-2
BPP-2 is a GHSR ligand containing the element F. By labeling BPP-2 with the isotope 18F, a PET probe targeting GHSR can be produced. The binding affinity (Ki) of 18F-BPP-2 for GHSR is 274 nM.Formule :C27H28FN5O2Masse moléculaire :473.2227Isobutyryl-L-carnitine
CAS :Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.Formule :C11H21NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :231.29NPFF2-R ligand 1
NPFF2-R ligand 1 (Compound 16a) is an NPFF2-R ligand with Ki values of 228 nM for NPFF1-R and 27 nM for NPFF2-R, and can be utilized in research on central nervous system-related disorders.
Formule :C32H41N3OMasse moléculaire :483.32496Neuropeptide Y (human) free acid
CAS :Neuropeptide Y (human) free acid is the deamidated form of Neuropeptide Y (human, rat, mouse). The amidation of the C-terminal tyrosine in Neuropeptide Y is essential for its function, while the non-amidated form cannot initiate G-protein signaling.Formule :C189H284N54O58SMasse moléculaire :4270.06542CB1-IN-3
CB1-IN-3 (Compound 6i) is a potent inhibitor of the cannabinoid receptor type 1 (CB1). It holds potential for research in obesity, inflammation, and neurological disorders.Couleur et forme :Odour SolidGLP-1R/GIPR agonist-1
GLP-1R/GIPR agonist-1 is a dual receptor agonist for GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). It mimics the action of endogenous hormones GLP-1 and GIP, enhancing insulin secretion while suppressing glucagon release, thus lowering blood sugar. This compound is used in research related to metabolic disorders such as diabetes, obesity, and non-alcoholic steatohepatitis (NASH).Formule :C220H342N55O69Masse moléculaire :4858.49434SB 216641
CAS :SB 216641 is a 5-HT (1B/1D) antagonist with anxiolytic activity for the study of anxiety disorders and depression.Formule :C28H30N4O4Degré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :486.5620-SOLA
20-SOLA is the first water-soluble 20-HETE antagonist with oral bioavailability. It significantly improves blood pressure changes and kidney damage associated with the streptozotocin (STZ) diabetic mouse model. Additionally, 20-SOLA acts as a GPR75 receptor blocker. This compound is useful in research related to cardiovascular pathology.Formule :C33H62O9Masse moléculaire :602.43938Cyclosomatostatin Acetate
Cyclosomatostatin Acetate is an effective antagonist of the somatostatin receptor.Cyclosomatostatin Acetate inhibits SSTR1 signaling and decreases cell
Formule :C46H61N7O8Degré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :840.02Ref: TM-T21567L
1mg150,00€2mg251,00€5mg373,00€10mg568,00€25mg843,00€50mg1.130,00€100mg1.529,00€200mg2.062,00€TRAP-5 amide
CAS :TRAP-5 amide is a peptide agonist for protease-activated receptor 1 (PAR 1) [1].Formule :C30H51N9O6Couleur et forme :SolidMasse moléculaire :633.78Somatostatin 1-28 acetate
Somatostatin 1-28 acetate circulates in human plasma.Degré de pureté :99.22%Couleur et forme :SoildGPR183 antagonist-3
GPR183 antagonist-3 (compound 33) is an orally active GPR183 antagonist with an IC50 value of 8.7 μM. It demonstrates significant in vitro anti-migration and anti-inflammatory activity in monocytes and can alleviate pathological symptoms in experimental colitis induced by dextran sulfate sodium.Formule :C21H19BrN4O2SMasse moléculaire :470.04121MRS 4062 triethylammonium salt
CAS :MRS 4062 triethylammonium salt is a selective P2Y4 receptor agonist (EC50 values are 23, 640, and 740 nM for hP2Y4, hP2Y2 and hP2Y6 respectively).Formule :C42H86N7O15P3Couleur et forme :SolidMasse moléculaire :1022.105Palmitoyl tetrapeptide-20 TFA
Palmitoyl tetrapeptide-20 (PTP20) TFA is a biomimetic peptide and acts as an agonist of α-MSH. It protects follicular melanocytes by boosting catalase expression and activating melanogenesis.Formule :C38H70N6O8·xC2HF3O2GW-328267
CAS :GW-328267 is an agonist of the adenosine A2 receptor.Formule :C21H26N10O4Couleur et forme :SolidMasse moléculaire :482.5Albiglutide Fragment
CAS :Albiglutide fragment is a 30-amino-acid sequence of modified human GLP-1 (fragment 7-36).Formule :C148H224N40O45Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3283.6[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide
CAS :Potent, selective NPY Y5 receptor agonist; IC50: 0.24 nM (Y5), >500 nM (Y2), 530 nM (Y1), 51 nM (Y4); Ki: 0.1-0.15 nM (Y5); increases food intake in vivo.Formule :C183H281N57O54S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4207.67Alosetron-d3
CAS :Alosetron D3 (GR 68755 D3) is a deuterium-labeled Alosetron. Alosetron is an antagonist of 5HT3-receptor.Formule :C17H18N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :297.37γ-2-MSH (41-58), amide
CAS :Melanocortin (MC) 3-MSH (Melanocyte-Stimulating Hormone) is believed to signal through the MC 3 receptor.Formule :C74H100N22O15SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1569.79CCK (26-31) (non-sulfated)
CAS :CCK (26-31) is a digestive, satiety-inducing, anxiety-related peptide fragment from CCK hormone in the brain and gut.Formule :C38H50N8O10S2Couleur et forme :SolidMasse moléculaire :842.98Canine KP-10
Canine KP-10 is a potent kisspeptin that induces a significant gonadotropin and estradiol response in female dogs during estrus.Couleur et forme :Odour SolidCIA-1 (Free base)
CAS :CIA-1, a COUP-TFII inhibitor, has IC50 of 1.2-7.6 μM in prostate cancer cells; inhibits tumor growth in mouse prostate cancer.Formule :C17H19N3O2SDegré de pureté :99%Couleur et forme :SolidMasse moléculaire :329.4215-keto-17-phenyl trinor Prostaglandin F2α ethyl amide
CAS :Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which hasFormule :C25H35NO4Couleur et forme :SolidMasse moléculaire :413.558Dabelotine, (R)-
CAS :Dabelotine, (R)- is the R-isomer of Dabelotine. Dabelotine is an adrenergic agonist used in the study of dementia.Formule :C15H22N2O2Couleur et forme :SolidMasse moléculaire :262.35ACTH (1-17)
CAS :ACTH (1-17), a potent MC1 receptor agonist with a Ki of 0.21 nM, is a variant of corticotropin from the pituitary gland.Formule :C95H145N29O23SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2093.4116-phenoxy tetranor Prostaglandin F2α
CAS :16-phenoxy PGF2α is a metabolically stable analog of PGF2α. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α.Formule :C22H30O6Couleur et forme :SolidMasse moléculaire :390.47Cortagine
Potent CRF1 agonist, EC50 = 0.18 nM in rats. Exhibits in vivo anxiolytic and antidepressant effects; reduces mouse defensive behavior.Formule :C192H323N55O63SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4442.06Neuropeptide Y (22-36)
CAS :Neuropeptide Y (22-36) is a 15-amino acid fragment of NPY, which is abundant in the mammalian brain and involved in multiple physiological functions.Formule :C85H139N29O21Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1903.19Urocortin II, human acetate
Urocortin II, human acetate, is a selective endogenous peptide agonist of type 2 corticotropin-releasing factor (CRF2) receptors, used to study the role of CRF2 receptors in feeding behavior.Couleur et forme :Odour SolidProstaglandin F2α methyl ester
CAS :Prostaglandin F2α methyl ester is a highly lipid-soluble PGF2α analog used to maintain low intraocular pressure.Formule :C21H36O5Couleur et forme :SolidMasse moléculaire :368.51Urocortin II, human TFA
hUcn II, a CRF family member, targets CRF2 receptor, has time-linked stress regulation effects, showing mild motor suppression and delayed anxiolytic action.Formule :C196H340F3N63O56SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4564.3Cetirizine Impurity C dihydrochloride
CAS :Cetirizine Impurity C dihydrochloride is a Cetirizine metabolite and long-acting H1-antihistamine.Formule :C21H27Cl3N2O3Couleur et forme :SolidMasse moléculaire :461.81Ethylpropyltryptamine
CAS :Ethylpropyltryptamine (EPT) is an orally active novel psychoactive substance. It is predicted to act as a partial agonist of the 5-HT2A receptor.Formule :C15H22N2Couleur et forme :SolidMasse moléculaire :230.35Galanin (1-29)(rat, mouse)
CAS :Non-selective galanin agonist; Ki: GAL1-0.98, GAL2-1.48, GAL3-1.47 nM. Anticonvulsant, stops full seizures in rats.Formule :C141H211N43O41Degré de pureté :98%Couleur et forme :White Lyophilized PowderMasse moléculaire :3164.499Prolactin Releasing Peptide (1-31), human acetate
Prolactin Releasing Peptide (1-31), human (acetate), is a potent GPR10 ligand with high affinity, eliciting prolactin secretion.Formule :C162H26N56O44SCouleur et forme :SolidMasse moléculaire :3724.17CAY10580
CAS :CAY10580 is a potent and selective prostaglandin EP 4 receptor agonist ( K i =35 nM).Formule :C19H35NO4Couleur et forme :SolidMasse moléculaire :341.49Preclamol hydrochloride
CAS :Preclamol hydrochloride: selective dopamine agonist with research potential in schizophrenia.Formule :C14H22ClNOCouleur et forme :SolidMasse moléculaire :255.78S 16474
CAS :S 16474 is an antagonist of Neurokinin-1 Receptor.Formule :C44H48N6NaO8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :811.892FR252384
CAS :FR252384 is an antagonist of the neuropeptide Y-Y5 receptor (IC50: 2.3 nM).Formule :C18H17N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :275.35Amisulpride hydrochloride
CAS :Amisulpride is an antagonist of 5-HT7 receptor and dopamine D2 and D3 receptors. It modulates beta 2- arresting signaling and increases neurite outgrowth.Formule :C17H28ClN3O4SCouleur et forme :SolidMasse moléculaire :405.94VU0453379 hydrochloride
VU0453379 hydrochloride: selective CNS-penetrant GLP-1R PAM, EC50 1.3 μM.Formule :C26H35ClN4O2Couleur et forme :SolidMasse moléculaire :471.03Leukotriene B4 Ethanolamide
CAS :LTB4 binds to BLT1 (high affinity) and BLT2. LTB4-EA, a metabolite, is a stronger BLT1 antagonist, suggesting anti-inflammatory properties.Formule :C22H37NO4Couleur et forme :SolidMasse moléculaire :379.541PSB 0777 ammonium salt
CAS :adenosine A2A receptor full agonistFormule :C18H24N6O7S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :500.5511-deoxy Prostaglandin E2
CAS :11-deoxy PGE2 is a synthetic PGE2 analog, a potent bronchoconstrictor, 5-30x stronger than PGF2α on human respiratory muscles.Formule :C20H32O4Couleur et forme :SolidMasse moléculaire :336.47L-threo Lysosphingomyelin (d18:1)
CAS :L-threo Lysosphingomyelin, a natural S1P receptor agonist, has EC50s: 19.3 nM (hS1P1), 131.8 nM (hS1P3), 313.3 nM (hS1P2).Formule :C23H49N2O5PCouleur et forme :SolidMasse moléculaire :464.62[Phe8Ψ(CH-NH)-Arg9]-Bradykinin
CAS :Selective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage.Formule :C50H75N15O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1046.23L-770644
CAS :L-770644 is an agonist of B3 adrenergic receptor.Formule :C30H37N7O4SCouleur et forme :SolidMasse moléculaire :591.72GLP-1 moiety from Dulaglutide
GLP-1 moiety from Dulaglutide is a 31-amino acid fragment of Dulaglutide which is a glucagon-like peptide 1 receptor (GLP-1) agonist.Formule :C149H221N37O49Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3314.62Sauvagine
CAS :CRF receptor agonist; Ki: 9.4 nM (hCRF-R1), 9.9 nM (rCRF-R2a), 3.8 nM (mCRF-R2b) for 125I-[D-Tyr1]astressin binding inhibition.Formule :C202H346N56O63SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4599.35ABT-702
CAS :ABT-702 is an orally active, competitive, and reversible non-nucleoside adenosine kinase (AK) inhibitor analgesic and anti-inflammatory.Formule :C22H19BrN6ODegré de pureté :99.57%Couleur et forme :SoildMasse moléculaire :463.33IRL-1038
CAS :ETB endothelin receptor antagonistFormule :C68H92N14O15S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1409.67Bamosiran
CAS :Bamosiran, a small interfering RNA (siRNA), specifically targets the β-adrenergic receptor 2 to reduce intraocular pressure.Couleur et forme :SolidMK-0493 HCl
CAS :MK-0493 is a novel, potent, and selective agonist for melanocortin receptor 4 (MC4R).Formule :C30H39Cl2F2N3O2Couleur et forme :SolidMasse moléculaire :582.55PHM-27 (human)
CAS :Human-derived peptide, VIP/PHM 27 analog, boosts insulin by targeting calcitonin receptor with an EC50 of 11 nM.Formule :C135H214N34O40SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2985.44Urocortin II, human
Human urocortin (hUcn) II is a new member of the corticotropin-releasing-factor (CRF) family. It selectively binds to the CRF2 receptor.Formule :C194H339N63O54SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4450.28MGV354
MGV354 is a soluble activator of guanylate cyclase(sGC) with EC 50 s of <0.5 nM, and 5 nM in CHO and GTM-3 E cells, respectively [1] [2].Formule :C35H37N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :575.715(S)-HpEPE
CAS :15(S)-HpEPE, a monohydroperoxy fatty acid, forms when 15-lipoxygenase acts on EPA, with expected biological activities akin to 15(S)-HpETE.Formule :C20H30O4Couleur et forme :SolidMasse moléculaire :334.456Sarafotoxin S6a
CAS :Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo.Formule :C105H156N28O34S5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2514.85Levocarnitine propionate hydrochloride
CAS :Levocarnitine propionate hydrochloride (ST-261) is used for the treatment of the deterioration of renal function, congestive heart failure, and other diseases.Formule :C10H20ClNO4Degré de pureté :90% - 99.77%Couleur et forme :SolidMasse moléculaire :253.72ONO-0300302
CAS :ONO-0300302: LPA1 antagonist, treats Benign Prostatic Hyperplasia, IC50 = 0.16 nM, reduces IUP in rats and dogs for 12h.Formule :C29H35NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.59Clozapine N-oxide dihydrochloride
CAS :Clozapine N-oxide dihydrochloride is a derivative of Clozapine and an agonist of DREADDs.Formule :C18H21Cl3N4ODegré de pureté :98.11%Couleur et forme :SolidMasse moléculaire :415.74α1A-AR Degrader 9c
CAS :α1A-AR Degrader 9c is a potent, selective, and reversible PROTAC degrader targeting the α1A adrenergic receptor (α1A-AR) with a DC50 of 2.86 μM.Formule :C38H43N11O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :829.82Adrenocorticotropic Hormone (ACTH) (1-39), rat TFA
Adrenocorticotropic Hormone (ACTH) (1-39), rat (TFA) is a potent melanocortin 2 receptor (MC2) agonist.Formule :C212H316F3N57O59SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4696.181-39-Corticotropin (human)(TFA)
ACTH (1-39) human (TFA) is a melanocortin agonist that boosts adrenal CS production and affects the CNS and immune system.Formule :C207H308N56O58S·C2HF3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4655.16Naratriptan D3 Hydrochloride
CAS :Naratriptan D3 Hydrochloride is the deuterium labeled Naratriptan, is a selective agonist of 5-HT1 receptor subtype.Formule :C17H26ClN3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :374.94TT-OAD2 free base
CAS :TT-OAD2 free base, a non-peptide GLP-1 receptor agonist, can treat diabetes; has an EC50 of 5 nM.Formule :C50H47Cl2N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :856.83HCGRP-(8-37)
CAS :Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonistFormule :C139H230N44O38Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3125.59FSLLRY-NH2
CAS :PAR2 antagonist; counters taxol effects, PKC in mice; inhibits ERK, collagen in fibroblasts; lessens dermatophyte itch in mice.Formule :C39H60N10O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :796.97Myristoylated ARF6 (2-13)
Myristoylated ARF6 (2-13) inhibits the MyD88–ARNO–ARF6 signaling axis by inactivating ARF6.Formule :C74H128N16O18Masse moléculaire :1528.95925Donitriptan hydrochloride
CAS :Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectivelyFormule :C23H26ClN5O2Degré de pureté :99.8% - 99.86%Couleur et forme :SolidMasse moléculaire :439.94Ref: TM-T21666
2mg40,00€5mg49,00€10mg64,00€25mg135,00€50mg240,00€100mg339,00€200mg439,00€500mgÀ demanderSPN009
SPN009 (Sequence 3) is a GLP-1 receptor (GLP-1 Receptor) agonist, with an EC50 of 2.84 nM, and improves type 2 diabetes in DB/DB mouse models.Formule :C191H299N45O59Masse moléculaire :4167.17798palm-PrRP31
palm-PrRP31 is a potent dual agonist for GPR10 (EC50=72 pM) and NPFF-R2. It activates downstream signaling pathways by binding to GPR10 and NPFF-R2 receptors, leading to reduced appetite and increased energy expenditure. palm-PrRP31 can be utilized to investigate its mechanism of action in the nervous system, thereby elucidating the complex biological processes involved in the regulation of appetite and energy expenditure.Formule :C176H282N56O43SMasse moléculaire :3900.1322Galanin (1-15) (porcine, rat)
CAS :N-terminal galanin fragment used to mediate central cardiovascular effectsFormule :C72H105N19O20Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1556.72Neocarzinostatin
CAS :Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :N/AAtrial natriuretic factor (1-28) (rat) TFA
ANP (1-28), rat (TFA) inhibits Ang II-induced endothelin-1 secretion; main circulating ANP form in rats.Formule :C130H206N45F3O41S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3176.43Thromboxane B1
CAS :Thromboxane B1 (TXB1) is a lipid eicosanoid, part of the TXB family, involved in blood clotting.Formule :C20H36O6Couleur et forme :SolidMasse moléculaire :372.5ALD1613
ALD1613 is a potent neutralizing monoclonal antibody targeting adrenocorticotropic hormone (ACTH). It neutralizes ACTH-induced signaling and inhibits cyclic adenosine monophosphate accumulation in ACTH-stimulated Y1 (mouse adrenal cell line) via all five melanocortin receptors. ALD1613 significantly reduces plasma corticosterone levels in wild-type rats and is applicable in studies involving elevated ACTH-related conditions.Couleur et forme :Odour LiquidGuanylin TFA (mouse,rat)
Guanylin (mouse, rat) TFA is a peptide composed of 15 amino acids and acts as an activator of intestinal guanylate cyclase. This compound is utilized in research related to diarrhea.Formule :C60H90N16O22S4·xC2HF3O2Couleur et forme :SolidMasse moléculaire :1515.71 (free base)SB 699551
CAS :SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.Formule :C34H45N3ODegré de pureté :99.83%Couleur et forme :SoildMasse moléculaire :511.74Ref: TM-T23325L
1mg190,00€5mg471,00€10mg662,00€25mg1.036,00€50mg1.429,00€100mg1.821,00€200mg2.489,00€Cloprostenol isopropyl ester
CAS :(+)-Chloprostol is a PGF2α agonist, mimics prostaglandin F2α, induces luteal dissolution in mares without side effects or stress.Formule :C25H35ClO6Couleur et forme :SolidMasse moléculaire :466.99
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