GPCR/G-Protéine
Les inhibiteurs des GPCR/protéines G sont des composés qui ciblent les récepteurs couplés aux protéines G (GPCR) et les protéines G associées, qui jouent un rôle crucial dans la transmission des signaux de l'extérieur vers l'intérieur des cellules. Ces inhibiteurs sont essentiels pour étudier les voies de signalisation médiées par les GPCR, impliquées dans de nombreux processus physiologiques, y compris la perception sensorielle, la réponse immunitaire et la neurotransmission. Les inhibiteurs des GPCR sont également importants dans le développement de médicaments, car de nombreux agents thérapeutiques ciblent ces récepteurs. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de GPCR/protéines G de haute qualité pour soutenir vos recherches en pharmacologie, biologie cellulaire et domaines connexes.
Sous-catégories appartenant à la catégorie "GPCR/G-Protéine"
- récepteur 5-HT(1.024 produits)
- Récepteur d'adénosine(249 produits)
- Récepteur adrénergique(3.029 produits)
- Récepteur de la bombésine(35 produits)
- Récepteur de la bradykinine(61 produits)
- CXCR(159 produits)
- CaSR(34 produits)
- Récepteur cannabinoïde(217 produits)
- Cholécystokinine(1 produits)
- Récepteur de la dopamine(443 produits)
- Récepteur de l'endothéline(86 produits)
- Récepteur GNRH(84 produits)
- GPCR19(33 produits)
- GRK(33 produits)
- GTPase(22 produits)
- Récepteur du glucagon(196 produits)
- Hérisson/Smoothened(49 produits)
- Récepteur de l'histamine(385 produits)
- Récepteur LPA(21 produits)
- Récepteur de la mélatonine(26 produits)
- Récepteur OX(42 produits)
- Récepteur opioïde(326 produits)
- PAFR(14 produits)
- PKA(53 produits)
- Récepteur S1P(17 produits)
- SGLT(31 produits)
- Récepteur Sigma(46 produits)
Affichez 19 plus de sous-catégories
5980 produits trouvés pour "GPCR/G-Protéine"
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dCNP
<p>dCNP binds to NPR-B/C receptors (NPR-B/C receptor), initiating the cGMP signaling pathway and regulating vascular function. It exhibits anti-hypoxic effects by downregulating hypoxia-related genes such as HIF1α and HIF2α. Additionally, dCNP inhibits tumor stroma induction, demonstrating antifibrotic properties. It also enhances immune response by upregulating CTL, NK cells, and conventional type 1 dendritic cells in tumors.</p>Formule :C141H248N38O36S3Couleur et forme :SolidMasse moléculaire :3147.91HAEGTFTSD acetate(926018-45-3 free base)
HAEGTFTSD acetate is the first N-terminal 1-9 residues of GLP-1 peptide.The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted fromFormule :C42H61N11O19Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1024.01ADTN
CAS :ADTN is an agonist of the dopamine receptor.Formule :C10H13NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :179.22IRAK inhibitor 4 trans
IRAK inhibitor 4 targets and blocks IRAK4 activity; refers to its trans molecular configuration.Formule :C33H35F3N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :620.66Cortistatin-29 (rat) (trifluoroacetate salt)
CAS :Cortistatin-29, similar to somatostatin-28, derives from preprocortistatin and binds to SST receptors 1-5 with varying IC50 values.Formule :C161H240N46O41S2Couleur et forme :SolidMasse moléculaire :3540.0913,14-dihydro Prostaglandin F2α
CAS :13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain.Formule :C20H36O5Couleur et forme :SolidMasse moléculaire :356.503JNJ-39933673
CAS :JNJ-39933673 is a bio-active chemical.Formule :C48H54F2N2O11Couleur et forme :SolidMasse moléculaire :872.965-hydroxy Propranolol
CAS :5-hydroxy Propranolol, a propranolol metabolite, is formed in the liver via P450 2D6.Formule :C16H21NO3Couleur et forme :SolidMasse moléculaire :275.348Norisoboldine hydrochloride
CAS :<p>Norisoboldine hydrochloride: an oral AhR agonist from Radix Linderae, for Rheumatoid arthritis and Ulcerative colitis research.</p>Formule :C18H20ClNO4Couleur et forme :SolidMasse moléculaire :349.81Vanicoside E
CAS :Vanicoside E is an antioxidant and antitumor agent. Vanicoside E inhibits L-Tyrosine and L-DOPA with IC 50 s of 45.23 μM and 189.96 μM, respectively [1] [2] .Formule :C53H52O22Couleur et forme :SolidMasse moléculaire :1040.97Apigenin 6,8-di-C-α-L-arabinopyranoside
CAS :Apigenin 6,8-di-C-alpha-L-arabinopyranoside is a useful organic compound for research related to life sciences.Formule :C25H26O13Couleur et forme :SolidMasse moléculaire :534.47TGR5 agonist 6
CAS :Compound 22b, also known as TGR5 agonist 6, is a non-systemic, intestine-targeted TGR5 agonist that demonstrates significant and sustained blood glucose-lowering effects with an acceptable safety profile.Formule :C42H48Cl2N6O6Couleur et forme :SolidMasse moléculaire :803.77Urocortin II, mouse
CAS :Mouse Urocortin II: Selective CRF2 agonist, Ki 0.66 nM for CRFR2, >100 nM for CRFR1, affects central neural circuits.Formule :C187H320N56O50Couleur et forme :SolidMasse moléculaire :4152.96Benzomalvin A
CAS :Benzomalvin A is a filamentous fungal secondary metabolite.Formule :C24H19N3O2Couleur et forme :SolidMasse moléculaire :381.43SR 142948 TFA
SR 142948 TFA is an orally active, selective non-peptide neurotensin receptor (NT) antagonist, displaying IC50 values of 1.19 nM in h-NTR1-CHO cells, 0.32 nM in HT-29 cells, and 3.96 nM in adult rat brain. In HT-29 cells, it counteracts NT-induced inositol monophosphate formation with an IC50 of 3.9 nM. It blocks NT-induced hypothermia, analgesia, and turning behavior in vivo and can cross the blood-brain barrier, making it useful for research in psychiatric disorders.Couleur et forme :Odour SolidCIA-1 (Free base)
CAS :CIA-1, a COUP-TFII inhibitor, has IC50 of 1.2-7.6 μM in prostate cancer cells; inhibits tumor growth in mouse prostate cancer.Formule :C17H19N3O2SDegré de pureté :99%Couleur et forme :SolidMasse moléculaire :329.42Org 13011
CAS :Org 13011 has CNS activity and induces conditioned taste aversion by mediating 5-HT 1A receptors.Formule :C18H25F3N4ODegré de pureté :98.02%Couleur et forme :SoildMasse moléculaire :370.41Ref: TM-T28258L
1mg115,00€5mg275,00€10mg394,00€25mg615,00€50mg848,00€100mg1.121,00€200mg1.510,00€1mL*10mM (DMSO)281,00€Adatanserin hydrochloride
CAS :Adatanserin hydrochloride (WY50324 hydrochloride) is a 5-HT(1A)/5-HT(2) receptor ligand that is neuroprotective and may be used in the study of depression.Formule :C21H32ClN5ODegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :405.96Dehydro Aripiprazole (hydrochloride)
CAS :Dehydro aripiprazole, an active atypical antipsychotic metabolite of aripiprazole, is formed by CYP3A4 and CYP2D6.Formule :C23H26Cl3N3O2Couleur et forme :SolidMasse moléculaire :482.83Dabelotine, (R)-
CAS :Dabelotine, (R)- is the R-isomer of Dabelotine. Dabelotine is an adrenergic agonist used in the study of dementia.Formule :C15H22N2O2Couleur et forme :SolidMasse moléculaire :262.35BM213 acetate
<p>BM213 acetate is a selective C5aR1 agonist with antitumor activity that induces C5aR1-mediated calcium mobilization and pERK1/2 signaling.</p>Formule :C45H74N12O12Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :975.14Nolomirole
CAS :Nolomirole is a dopamine receptor agonist that reduces symptoms of congestive heart failure caused by monoclinine.Formule :C19H27NO4Couleur et forme :SolidMasse moléculaire :333.42ZM 253270
CAS :ZM 253270 is an nonpeptide neurokinin A antagonist.Formule :C22H26ClN7O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :471.95Lanepitant 2HCl
CAS :Lanepitant 2HCl is a non-peptide neurokinin-1 receptor antagonist that can be used to study painful neuropathy-like disorders such as migraine.Formule :C33H47Cl2N5O3Degré de pureté :98.67%Couleur et forme :SolidMasse moléculaire :632.66Secretin (28-54), human
CAS :Secretin (28-54), human, is a 27-amino acid residue peptide with a C-terminal amidation, acting on human secretin receptors.Formule :C130H220N44O40Degré de pureté :98%Couleur et forme :PowderMasse moléculaire :3039.46Adenosine receptor antagonist 1
CAS :A2aR-selective antagonist with IC50 of 0.29 nM; 14x more selective over A2bR.Formule :C22H15ClFN7OCouleur et forme :SolidMasse moléculaire :447.86Secretin, canine TFA
Secretin, canine TFA, is an endocrine hormone that stimulates the secretion of pancreatic fluid rich in bicarbonate. Additionally, Secretin, canine TFA, can regulate the primary cell functions and paracellular permeability of gastric monolayer cells through an Src kinase-dependent pathway.Couleur et forme :Odour SolidBim 21009
CAS :Bim 21009 is an inhibitor of gonadorelin.Formule :C74H92ClN17O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1463.08GM-60186
GM-60186, a potent inhibitor of the 5-HT receptor 2B (HTR2B) with an IC50 of 257 nM, effectively suppresses the proliferation and migration of colorectal cancer cells.Formule :C30H33FN2O4Couleur et forme :SolidMasse moléculaire :504.59JNJ-5207787
CAS :JNJ-5207787, a blood-brain barrier-crossing Y2 receptor antagonist, is >100x selective against Y1/Y4/Y5 and inhibits human/rat Y2 with pIC50s of 7.0/7.1.Formule :C32H38N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :510.67GIP/GLP-1 dual receptor agonist-1
CAS :Compound 4: GIP/GLP-1 agonist for metabolic/fatty liver disease research.Couleur et forme :SolidAlprostadil ethyl ester
CAS :<p>Alprostadil ethyl ester is a biochemical used in the treatment of scleroderma.</p>Formule :C22H38O5Couleur et forme :SolidMasse moléculaire :382.53Tetrahydro-β-carboline
CAS :Compound Fr12161, with CAS No. 16502-01-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12161 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C11H12N2Degré de pureté :96.31%Couleur et forme :Tan SolidMasse moléculaire :172.2264Conessine hydrobromide
CAS :Conessine hydrobromide is a naturally occurring steroid alkaloid and has been used in traditional herbal medicine as a treatment for amoebic dysentery.Formule :C24H41BrN2Couleur et forme :SolidMasse moléculaire :437.51PHM-27 (human)
CAS :<p>Human-derived peptide, VIP/PHM 27 analog, boosts insulin by targeting calcitonin receptor with an EC50 of 11 nM.</p>Formule :C135H214N34O40SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2985.44GRL093-22
GRL093-22 is an effective and selective inhibitor of G protein-coupled receptor kinases (GRK), with IC50 values of 60 nM for GRK5 and 40 nM for GRK6. It shows potential for research in heart failure and multiple myeloma.Formule :C33H29FN6O3Couleur et forme :SolidMasse moléculaire :576.62LHRH, Ala(6)-
CAS :LHRH, Ala(6)- is a synthetic luteinizing hormone-releasing hormone agonist agent.Formule :C56H77N17O13Couleur et forme :SolidMasse moléculaire :1196.32Rubraxanthone
CAS :Rubraxanthone is a PAF inhibitor isolated from Garcinia parvifolia Miq.Formule :C24H26O6Couleur et forme :SolidMasse moléculaire :410.466CART(55-102)(rat) TFA
Rat CART(55-102) TFA suppresses appetite, links to leptin/neuropeptide Y, and may induce anxiety/stress.Formule :C228H368F3N65O67S7Couleur et forme :SolidMasse moléculaire :5373.2ARC 239 dihydrochloride
CAS :ARC 239 dihydrochloride is a selective α2B adrenoceptor antagonist (pKD values are 8.8, 6.7 and 6.4 at α2B, α2A, and α2D receptors respectively).Formule :C24H31Cl2N3O3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :480.43α-helical CRF 9-41 acetate
<p>α-helical CRF 9-41 acetate is a competitive antagonist of CRF2 (KB = 100 nM) and a partial agonist of CRF1 (EC50 = 140 nM).</p>Degré de pureté :96.60%Couleur et forme :SolidMasse moléculaire :#N/ARef: TM-TP2048L
1mg208,00€5mg500,00€10mg672,00€25mg1.017,00€50mg1.359,00€100mg1.853,00€200mg2.498,00€MDL 19301
CAS :MDL 19301 is a nonsteroidal, anti-inflammatory agent.Formule :C15H21NS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :279.46Bucindolol Formate
Bucindolol is a β1-adrenergic blocker with sympathomimetic activity, used in heart failure research.Formule :C23H27N3O4Degré de pureté :99.76% - 99.88%Couleur et forme :SolidMasse moléculaire :409.48Ref: TM-T10631L
1mg185,00€5mg415,00€10mg613,00€25mg938,00€50mg1.311,00€100mg1.768,00€500mg3.535,00€1mL*10mM (DMSO)465,00€5-trans Latanoprost
CAS :Latanoprost, an F-series prostaglandin analog for ocular hypertension, has a 5-trans isomer used as an analytical standard.Formule :C26H40O5Couleur et forme :SolidMasse moléculaire :432.601CB2R/FAAH modulator-3
CAS :CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH.Formule :C22H31NO2Degré de pureté :99.81%Couleur et forme :SoildMasse moléculaire :341.49Mosliciguat
CAS :Mosliciguat is a guanylate cyclase activator.Formule :C41H36ClF3N2O5Couleur et forme :SolidMasse moléculaire :729.1915(R)-Pinane Thromboxane A2
CAS :15(R)-PTA2 is an (R)-epimer of PTA2; doesn't inhibit platelet aggregation or gastric tone; less effective than PTA2 at blocking prostaglandin contraction.Formule :C24H40O3Couleur et forme :SolidMasse moléculaire :376.581[D-Trp11]-Neurotensin
CAS :[D-Trp11]-Neurotensin, selective NT antagonist in rat hearts, agonist in guinea pig atria/rat stomach, blocks NT-induced hypotension.Formule :C80H122N22O19Masse moléculaire :1695.991Vensemaglutide
CAS :Vensemaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist, utilized in research related to diabetes or other metabolic disorders.Formule :C214H337N49O67Masse moléculaire :4668.25Prostaglandin E3
CAS :Prostaglandin E3 (PGE3) is an eicosapentaenoic acid (EPA) derivative with anti-inflammatory and anti-tumor activity, and shows anti-proliferative effects.Formule :C20H30O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :350.45Rhazimine
CAS :Rhazimine is an indole alkaloid. It is a dual inhibitor of arachidonic acid metabolism and platelet activating factor-induced platelet aggregation.Formule :C21H22N2O3Couleur et forme :SolidMasse moléculaire :350.418NTRC-824
CAS :NTRC-824: NTS2 antagonist, 150x more selective than NTS1; IC50: 38 nM, Ki: 202 nM; nonpeptide, neurotensin-like.Formule :C25H26F3N3O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :553.55Prostaglandin J2
CAS :PGJ2, a PGD2 metabolite, is a DP agonist (Ki: 0.9 nM hDP, 6.6 nM hCRTH2), induces cAMP (EC50: 1.2 nM), oxidative stress, neuronal apoptosis, and neurotoxicity.Formule :C20H30O4Couleur et forme :SolidMasse moléculaire :334.45A2A/A3 AR antagonist-1
A2A/A3 AR antagonist-1 is a dual fluorescent AR ligand with K i of 90 nM (hA2A) & 31.8 nM (hA3).Formule :C56H71N15O12S2Couleur et forme :SolidMasse moléculaire :1210.39Benzquinamide
CAS :<p>Benzquinamide (P2647), an antiemetic agent with anticancer activity, inhibits p-glycoprotein-mediated drug efflux and potentiates the cytotoxicity of anticancer</p>Formule :C22H32N2O5Degré de pureté :94.86%Couleur et forme :SolidMasse moléculaire :404.5Linaclotide acetate
CAS :<p>Linaclotide acetate, an oral guanylate cyclase C agonist with 14 amino acids, treats constipation-predominant IBS and chronic constipation.</p>Formule :C61H83N15O23S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1586.79P4pal10 TFA
P4pal10 TFA, the TFA salt form of P4pal10, serves as an antagonist of the protease-activated receptor 4 (PAR4). This compound inhibits platelet aggregation and thrombin generation induced by tissue factor (TF), exhibiting anticoagulant and antithrombotic activities. Additionally, P4pal10 TFA alleviates carrageenan-induced edema and neutrophil infiltration, and ameliorates damage in rat myocardial ischemia/reperfusion (I/R) models.Couleur et forme :Odour SolidNXT-10796
NXT-10796 is an orally active, intestinally restricted agonist of the EP4 receptor [1].Formule :C23H31N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :445.51SU 4029 dihydrochloride
CAS :SU 4029 dihydrochloride is a bioactive chemical.Formule :C9H21Cl2N3OCouleur et forme :SolidMasse moléculaire :258.19Alkyne-βAG-TOCA
Alkyne-βAG-TOCA is an octreotide derivative that targets somatostatin receptor subtype 2 (SST2). It is utilized in the synthesis and research of radioconjugates (RDC).Formule :C48H65N11O15S2Couleur et forme :SolidMasse moléculaire :1100.22REGN-7544
<p>REGN-7544 is a humanised monoclonal antibody targeting NPR1, which blocks and inhibits NPR1 to increase blood pressure, hypotensione.</p>Degré de pureté :95%Couleur et forme :Odour LiquidAtrial natriuretic peptide (3-28) (human)
CAS :Atrial natriuretic peptide (3-28) (human) (ANP (3-28) (human)), a peptide hormone produced by the atrial myocardium, plays a critical role in the regulation ofFormule :C118H187N43O36S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2880.21NK3R-IN-2
NK3R-IN-2 is an orally active NK3R inhibitor with an IC50 of 330.50 nM against human NK3R. It can penetrate the blood-brain barrier and exhibits excellent NK3R binding affinity in CHO-K1 cells (IC50= 87.31 nM). NK3R-IN-2 effectively suppresses luteinizing hormone (LH) levels and is applicable for research on hormone-related diseases.Couleur et forme :Odour SolidConopeptide rho-TIA
CAS :Conopeptide rho-TIA, a peptide from Conus tulipa venom, acts as a selective, noncompetitive inhibitor at the human α1B-Adrenergic Receptor and as a competitiveFormule :C105H160N36O21S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2390.88Angiopeptin
CAS :<p>Angiopeptin is a synthetic octapeptide analog of somatostatin; suppresses accelerated transplant atherosclerosis in rabbit heart arteries.</p>Formule :C54H71N11O10S2Couleur et forme :SolidMasse moléculaire :1098.34meta-Fluoxetine (hydrochloride)
CAS :meta-Fluoxetine (hydrochloride) can be used in related research in the field of life sciences. Its product number is T37474 and CAS number is 79088-29-2.Formule :C17H19ClF3NOCouleur et forme :SolidMasse moléculaire :345.79Human follicular gonadotropin releasing peptide
CAS :Human Follicular Gonadotropin Releasing Peptide (hF-GRP) is a hormonal peptide that, in vitro, can induce the secretion of pituitary luteinizing hormone (LH)Formule :C68H94N22O27Masse moléculaire :1651.61Meclinertant
CAS :<p>Meclinertant: selective NTS1 antagonist, blocks Ca2+ mobilization, with anxiolytic and anti-addictive properties.</p>Formule :C32H31ClN4O5Degré de pureté :97.51% - 99.44%Couleur et forme :SolidMasse moléculaire :587.07Lobeline sulfate
CAS :Lobeline sulfate, an alkaloid like nicotine, aids in smoking cessation, insomnia, and respiratory issues. Less potent on nicotinic receptors.Formule :C22H29NO6SDegré de pureté :98%Couleur et forme :White PowderMasse moléculaire :435.54MRS7925
MRS7925 (Compound 43) serves as a potent antagonist of the 5-HT2B receptor, with an inhibition constant (Ki) of 17 nM, and is utilized in the study of fibrosisFormule :C20H26IN5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :511.365-HT6R antagonist 6
5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.Formule :C24H26N4O2SCouleur et forme :SolidMasse moléculaire :434.55[D-Pro2] Spantide I TFA
[D-Pro2] Spantide I TFA is an analog of Spantide I, a selective antagonist of the NK1 receptor [1].Formule :C75H108N20O13·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidGalanin-Like Peptide (rat)
CAS :Galanin-Like Peptide (rat), a neuropeptide comprising 60 amino acids, plays a crucial role in regulating feeding, body weight, and energy metabolism [1].Formule :C288H461N87O83SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :6502.34Petrelintide acetate
Petrelintide (ZP8396) acetate is an amylin analog with potential for weight reduction, suitable for diabetes research.Formule :C185H305N49O61·xC2H4O2Couleur et forme :SolidMasse moléculaire :4191.69 (free base)NN1213
NN1213 (Peptide 21) is a long-acting human amylin peptide analogue that functions as a selective amylin receptor agonist. It has an EC50 of 0.177 nM for hAMY3R and 0.262 nM for rAMY3R. In both rat and dog models, NN1213 significantly reduces appetite and is utilized in anti-obesity research.Couleur et forme :Odour SolidLHRH
CAS :Luteinizing hormone-releasing hormone (LHRH) is a neuropeptide produced in the hypothalamus that plays a pivotal role in regulating reproduction and hasFormule :C55H74N16O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1183.27Tetrapeptide-1
CAS :Tetrapeptide-1 is a bioactive peptide renowned for its antioxidant properties and has been cited as an ingredient in cosmetics [1].Formule :C20H36N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.52α-CGRP (mouse, rat) TFA
α-CGRP (mouse, rat) TFA, a neuropeptide belonging to the calcitonin gene-related peptide (CGRP) family, is predominantly located at neuromuscular junctions andFormule :C162H262N50O52S2·C2HF3O2Degré de pureté :98%Couleur et forme :SolidHuman glucagon-like peptide-1-(7-36)-Lys(Biotin) amide
Biotin-labeled GLP-1-(7-36) amide; a gut peptide that enhances insulin release.Formule :C165H252N44O48SCouleur et forme :SolidMasse moléculaire :3652.1Prostaglandin K1
CAS :Prostaglandin K1 (compound 46) is a structurally modified prostanoid analog with an EC50 and Ki of 2800 nM for the EP1 receptor.Formule :C20H32O5Couleur et forme :SolidMasse moléculaire :352.474-Hydroxy MPT
CAS :4-Hydroxy MPT (4-OH-MPT) is a serotonin-active compound that acts as an agonist for 5-HT2A and 5-HT2B receptors, with EC50 values of 3.82 nM and 3.4 nM, respectively.Formule :C14H20N2OCouleur et forme :SolidMasse moléculaire :232.32LY 293284
CAS :LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.Formule :C19H26N2OCouleur et forme :SolidMasse moléculaire :298.42ZL-1101
ZL-1101 is a human monoclonal antibody (mAb) targeting TNFRSF4/OX40/CD134.Couleur et forme :Odour LiquidMLS1082
CAS :MLS1082 is a D1-like dopamine receptor (D1R) orthosteric modulatothat stimulates G-protein signaling upon dopamine activation for neurodegenerative disorders.Formule :C24H23N3O2Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :385.46PSB-1114 triethylamine
PSB-1114 triethylamine is a potent, enzymatically stable, P2Y2 receptor agonist with a 134 nM EC50, exhibiting greater than 50-fold selectivity over P2Y4 (EC50Formule :C10H15F2N3O13P3S·xC6H15NDegré de pureté :98%Couleur et forme :SolidPramlintide
CAS :Pramlintide, a polypeptide analog of human amylin, is an antidiabetic agent with antineoplastic properties in colorectal cancer.Couleur et forme :SolidBMS-753426
CAS :<p>BMS-753426 is a potent and orally bioavailable antagonist of CCR2 .</p>Formule :C25H33F3N6O2Couleur et forme :SolidMasse moléculaire :506.5745-HT2A receptor agonist-6
CAS :5-HT2A receptor agonist-6 (compound 47) is a selective agonist of the 5-HT2A receptor with a pEC50 value of 6.58.Formule :C18H19N3O3Couleur et forme :SolidMasse moléculaire :325.36AC 187 TFA
AC 187 TFA, a potent and orally active amylin receptor antagonist, exhibits an IC50 of 0.48 nM and a Ki of 0.275 nM.Formule :C129H206F3N37O42Couleur et forme :SolidMasse moléculaire :3004.27Sulamserod
CAS :Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular relatedFormule :C19H28ClN3O5SDegré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :445.96Mapenterol hydrochloride
CAS :Mapenterol hydrochloride is an agonist of β2-adrenergic receptor.Formule :C14H21Cl2F3N2ODegré de pureté :98.11% - 99.98%Couleur et forme :SolidMasse moléculaire :361.23Ref: TM-T40622
1mg52,00€5mg107,00€10mg158,00€25mg263,00€50mg378,00€100mg548,00€500mg1.093,00€1mL*10mM (DMSO)113,00€Emoghrelin
CAS :Emoghrelin, extracted from Heshouwu (Polygonum multiflorum), promotes the secretion of growth hormone by activating the ghrelin receptor [1].Formule :C24H22O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :518.42Prostaglandin H1
CAS :Prostaglandin H1 is the cyclooxygenase metabolite of DGLA, a CRTh2 agonist and a precursor of a family of 1 anti-inflammatory prostaglandins.Formule :C20H34O5Couleur et forme :SolidMasse moléculaire :354.487BE-24566B
CAS :BE-24566B, a polyketide from S. violaceusniger, inhibits various bacteria and blocks ET receptors (ETA IC50=11 μM, ETB=3.9 μM).Formule :C27H24O7Couleur et forme :SolidMasse moléculaire :460.482PAMP-12(human, porcine)
CAS :Potent endogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC50 = 57.2 nM). Corresponds to amino acids 9 to 20 of proadrenomedullin.Formule :C77H119N25O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1618.95Nebentan
CAS :<p>Nebentan (YM598) is an oral, selective ETA antagonist; Ki: 0.697 nM (ETA), 569 nM (ETB); may slow cor pulmonale, myocardial infarction.</p>Formule :C24H21N5O5SCouleur et forme :SolidMasse moléculaire :491.52Cetirizine methyl ester
CAS :Cetirizine methyl ester is a Cetirizine impurity, a long-acting, oral H1-antihistamine and hydroxyzine metabolite.Formule :C22H27ClN2O3Couleur et forme :SolidMasse moléculaire :402.91ACTH (11-24)
CAS :ACTH (11-24) is an adrenocorticotrophin fragment, stimulates cortisol, and antagonizes ACTH (1-39)/(1-10) in adrenal cells.Formule :C77H134N24O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1652.04FGH31
FGH31 (Compound 24), a dopamine D4 agonist, exhibits potent and selective GRK2-dependency with a K i of 1.6 nM and partially activates β-arrestin [1].Formule :C33H36N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :520.66CB2R agonist 3
CB2R agonist 3, a potent activator of cannabinoid receptor 2 (CB2R), exhibits an EC50 value of 0.37μM, indicative of its significant role in the immune system [Degré de pureté :98%Couleur et forme :Odour SolidVortioxetine D8
CAS :Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).Formule :C18H22N2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :306.5S(-)-Bisoprolol fumarate
CAS :S(-)-Bisoprolol fumarate is a selective β1-blocker for hypertension and heart research.Formule :C18H31NO4·xC4H4O4Couleur et forme :SolidMasse moléculaire :441.521Eletriptan
CAS :<p>Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.</p>Formule :C22H26N2O2SCouleur et forme :SolidMasse moléculaire :382.52ALD1613
<p>ALD1613 is a potent neutralizing monoclonal antibody targeting adrenocorticotropic hormone (ACTH). It neutralizes ACTH-induced signaling and inhibits cyclic adenosine monophosphate accumulation in ACTH-stimulated Y1 (mouse adrenal cell line) via all five melanocortin receptors. ALD1613 significantly reduces plasma corticosterone levels in wild-type rats and is applicable in studies involving elevated ACTH-related conditions.</p>Couleur et forme :Odour LiquidGuanylin(human) TFA
Guanylin (human) TFA, a 15-amino acid peptide, activates intestinal guanylate cyclase, regulating electrolyte and water transport via cGMP.Couleur et forme :LiquidSLP7111228
CAS :SLP7111228 is an effective and selective SphK1 inhibitor (Ki = 48 nM).Formule :C22H33N5OCouleur et forme :SolidMasse moléculaire :383.53Astressin
CAS :Astressin is a truncated CRF analog; binds strongly to receptor's extracellular domain, likely acting as a neutral competitive antagonist.Formule :C161H269N49O42Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3563.16ACTH (7-38) (human)
CAS :ACTH (7-38) (human) is a fragment (7-38) of the full human adrenocorticotropic hormone (ACTH (1-39)), also referred to as corticotropin inhibitory peptide (CIPFormule :C167H257N47O46Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3659.11MAO-B-IN-3
<p>MAO-B-IN-3 is a reversible, selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and demonstrates affinity for the 5-HT6 receptor with a Ki</p>Formule :C24H25N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.47L803
CAS :L803 is a selective somatostatin receptor type 4 (SST4) agonist that can inhibit L-type calcium channel currents (ICa). It holds potential for research into degenerative diseases of retinal ganglion cells (RGC), such as glaucoma.Formule :C50H80N13O19PCouleur et forme :SolidMasse moléculaire :1198.224-Methylhistamine
CAS :4-Methylhistamine serves as a potent agonist for the histamine 4 receptor (H4R), holding promise for research into immune-related diseases, including cancer andFormule :C6H11N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :125.17Rp-dUTPαS tetrasodium
Rp-dUTPαS (tetrasodium) is an isomer of the sulfur-containing nucleotide dUTP-α-S and acts as an agonist of the purinergic P2Y2 receptor. It selectively induces the accumulation of inositol phosphates in P2Y2-expressing 1321N1 cells with an EC50 of 12.5 μM.Couleur et forme :Odour SolidMaridebart
CAS :Maridebart is a humanized IgG1-kappa monoclonal antibody that targets the GIPR (gastric inhibitory polypeptide receptor) [1].Couleur et forme :LiquidProstaglandin F2α Alcohol
CAS :Prostaglandin F2α Alcohol is a PGF2α (T15133) analogue. Prostaglandin F2α Alcohol is an orally active prostaglandin F receptor (FP receptor) agonist.Formule :C20H36O4Couleur et forme :SolidMasse moléculaire :340.5PA-8
CAS :<p>PA-8: Selective PAC1 antagonist, orally active, blocks CREB phosphorylation & cAMP increase (IC50=2nM), reduces pain & aversive response in vivo.</p>Formule :C17H18N4O4Degré de pureté :97.64%Couleur et forme :SolidMasse moléculaire :342.35Nα-Methylhistamine FA
Nα-Methylhistamine FA is a histamine H3 receptor agonistFormule :C7H13N3O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :171.2CCR4 antagonist 3
CAS :Orally active CCR4 antagonist with piperidinyl-azetidine; IC50: 22 nM (calcium flux), 50 nM (CTX); antitumor effects.Formule :C24H27Cl2N7OCouleur et forme :SolidMasse moléculaire :500.43PG 106 acetate
PG 106 acetate: Selective hMC3 receptor antagonist, IC50=210 nM; inactive on hMC5 and hMC4, EC50=9900 nM.Formule :C53H73N13O11Degré de pureté :98.24%Couleur et forme :SolidMasse moléculaire :1068.23Picumeterol FA
picumeterol FA is a potent and selective β2-adrenergic receptor agonist.Formule :C22H31Cl2N3O4Degré de pureté :99.97%Couleur et forme :SoildMasse moléculaire :472.4Methimepip dihydrobromide
CAS :Methimepip dihydrobromide is a selective H3R agonist.Formule :C10H19Br2N3Couleur et forme :SolidMasse moléculaire :341.091Zenagamtide sodium
Zenagamtide is an agonist for both glucagon-like peptide-1 (GLP-1) and amylin receptors.Couleur et forme :Odour SolidMsh (11-13)
CAS :Msh (11-13) is a bioactive chemical.Formule :C16H30N4O4Couleur et forme :SolidMasse moléculaire :342.43Galanin (2-29) (rat)
CAS :Peptide agonist for galanin receptorsFormule :C139H208N42O40Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3107.4Binospirone
CAS :Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of movement disorders associated with neurologic dysfunction.Formule :C20H26N2O4Degré de pureté :97.57% - 98.96%Couleur et forme :SoildMasse moléculaire :358.43Ref: TM-T71138L
1mg115,00€5mg275,00€10mg394,00€25mg615,00€50mg848,00€100mg1.121,00€200mg1.539,00€1mL*10mM (DMSO)34,00€Ro60-0175
CAS :<p>Ro60-0175 is a selective 5-HT2B and 5-HT2C serotonin receptor agonist, often used as fumarate.</p>Formule :C11H12ClFN2Degré de pureté :97.09%Couleur et forme :SolidMasse moléculaire :226.68M40
CAS :Potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29) binding in ratFormule :C94H145N23O24Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1981.33L-770644
CAS :L-770644 is an agonist of B3 adrenergic receptor.Formule :C30H37N7O4SCouleur et forme :SolidMasse moléculaire :591.72Canine KP-10
Canine KP-10 is a potent kisspeptin that induces a significant gonadotropin and estradiol response in female dogs during estrus.Couleur et forme :Odour SolidB-Raf IN 14
CAS :B-Raf IN 14 is a BRAF inhibitor.Formule :C15H14BrN5O3SDegré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :424.27GEP44
GEP44 is a peptide-biased triple agonist targeting the glucagon-like peptide-1 receptor (GLP-1R), neuropeptide Y1 receptor (Y1-R), and neuropeptide Y2 receptor (Y2-R). It induces GLP-1R-dependent insulin secretion in rat and human islets by offsetting the actions of Y1-R and GLP-1R agonism, controlled by Y1-R antagonists. Additionally, GEP44 enhances glucose uptake in muscle tissue through Y1-R mediation independent of insulin and significantly reduces food intake and body weight in diet-induced obese rat models. GEP44 is utilized in studies related to obesity and type 2 diabetes.Couleur et forme :Odour SolidLGnRH-III, lamprey
CAS :GnRH III triggers luteinizing and follicle-stimulating hormone release, part of the conserved GnRH family.Formule :C59H74N18O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1259.33Carbazochrome salicylate
CAS :Carbazochrome salicylate can be used as a coagulant.Formule :C17H18N4NaO6Couleur et forme :White Crystalline PowderMasse moléculaire :397.343(R)-Zevaquenabant
(R)-Zevaquenabant ((R)-MRI-1867) is the enantiomer of Zevaquenabant. Zevaquenabant ((S)-MRI-1867) is a peripherally restricted, orally bioavailable dual antagonist of the cannabinoid CB1 receptor and inducible nitric oxide synthase (iNOS). It is beneficial in improving chronic kidney disease (CKD) caused by obesity.Couleur et forme :Odour SolidAnti-Mouse NK1.1 Antibody (PK136)
Anti-Mouse NK1.1 Antibody (PK136) is an IgG2a class antibody that targets NK1.1, inhibits NK1.1 signaling, and can be used to study heart and lung failure.Degré de pureté :95%Couleur et forme :Odour LiquidMasse moléculaire :150 kDaMotilin, canine
CAS :Motilin canine, a 22-amino acid peptide, functions as a robust gastrointestinal smooth muscle contraction agonist.Formule :C120H194N36O34Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2685.05MDL 29913
CAS :NK2 tachykinin receptor selective antagonist.Formule :C40H56N8O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :745Dexchlorpheniramine free base
CAS :Dexchlorpheniramine Maleate, a histamine receptor antagonist, is used to treat urticaria, allergic rhinitis, allergic conjunctivitis and pruritus.Formule :C16H19ClN2Degré de pureté :98%Couleur et forme :Oily Liquid SolidMasse moléculaire :274.79PD-149164
CAS :PD-149164 is an agonist of the CCK-A receptor.Formule :C33H38FN3O5Couleur et forme :SolidMasse moléculaire :575.67Pemvidutide TFA
Pemvidutide (TFA), a GLP-1R/GCGR dual agonist, effectively reduces body weight, liver fat, and serum lipid levels, and is utilized in research on non-alcoholicFormule :C182H275N39O54·xC2HF3O2Couleur et forme :SolidMasse moléculaire :3873.35 (free base)11β-Prostaglandin E2
CAS :11β-PGE2 is the C-11 epimer of PGE2.Formule :C20H32O5Couleur et forme :SolidMasse moléculaire :352.47AMK (hydrochloride)
CAS :AMK, a melatonin metabolite, scavenges oxygen, inhibits prostaglandin production, reduces lipid peroxidation, and affects Parkinson's in mouse studies.Formule :C12H17ClN2O3Couleur et forme :SolidMasse moléculaire :272.73Cyclosomatostatin TFA
Cyclosomatostatin TFA blocks SST receptor, reduces CRC cell growth, ALDH+ size, and sphere-formation.Formule :C46H58F3N7O8Couleur et forme :SolidMasse moléculaire :893.99[Ala17]-MCH acetate
[Ala17]-MCH acetate is a selective ligand for MCHR1 with a Ki of 0.16 nM and Kd of 0.37 nM(Eu3+ chelate-labeled).Formule :C99H159N29O28S4Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :2331.76PACAP-38 (16-38), human, mouse, rat
CAS :PACAP-38 (16-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine productionFormule :C123H215N39O28SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2720.33Atenolol
CAS :Atenolol (Tenormin) is a selective β1 receptor antagonist.Formule :C14H22N2O3Degré de pureté :99.07% - 99.95%Couleur et forme :White Crystalline Powder SolidMasse moléculaire :266.34LTB4-IN-2
LTB4-IN-2 (Compound 6x) is a selective inhibitor of Leukotriene B4 (LTB4), acting by specifically targeting the 5-Lipoxygenase-activating protein (FLAP) with anFormule :C24H17N5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :439.56Urocortin II, human
Human urocortin (hUcn) II is a new member of the corticotropin-releasing-factor (CRF) family. It selectively binds to the CRF2 receptor.Formule :C194H339N63O54SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4450.28PEN (rat)
CAS :PEN (rat) is an Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.Formule :C102H169N27O33Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2301.62Biotinyl-neuropeptide W-23 (human)
CAS :Biotinyl-neuropeptide W-23 (human) is a biotinylated form of neuropeptide W-23 (human), which functions as an agonist for the NPBW1 (GPR7) and NPBW2 (GPR8)Formule :C129H197N37O30S2Masse moléculaire :2810.3(+)-Dropropizine
CAS :(+)-Dropropizine can inhibit histamine receptor, anti-allergic, and reduce a cough by modulation of neuropeptides involved in the cough reflex.Formule :C13H20N2O2Degré de pureté :>99.99%Couleur et forme :White Or Off White Crystalline PowderMasse moléculaire :236.31Tau conotoxin CnVA
CAS :Tau conotoxin CnVA, a small peptide found in the venom of Conus consors (cone snail), is a member of the T1 cone snail peptide superfamily. It demonstrates high selectivity for the somatostatin sst3 receptor with a Ki value of 1.5 µM. Tau conotoxin CnVA is unique as the only known toxin interacting with this subfamily of G protein-coupled receptors (GPCR). This compound is useful for research related to diseases associated with the sst3 receptor, such as pancreatic cancer or pituitary adenomas.Formule :C72H116N24O17S4Couleur et forme :SolidMasse moléculaire :1718.1CRF(6-33)(human)
CAS :<p>CRFBP inhibitor peptide; blocks CRF, reduces weight gain, boosts activity in obese rats.</p>Formule :C141H231N41O43SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :3220.68DD202-114
CAS :DD202-114 is an effective and selective agonist of GLP1R. It promotes the accumulation of cAMP, reduces blood glucose levels, and decreases food intake. Additionally, DD202-114 holds potential for research in type 2 diabetes mellitus (T2DM) and obesity studies.Formule :C33H35FN4O5Masse moléculaire :586.65Acrinor
CAS :Acrinor is a adrenergic beta receptor agonist.Formule :C35H46Cl2N10O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :805.72LH-RH (4-10)
CAS :LH-RH (4-10), a heptapeptide from LHRH degradation, is made in macrophages and type II pneumocytes.Formule :C33H53N11O9Masse moléculaire :747.84Israpafant
CAS :Israpafant: PAF receptor blocker, IC50 0.84nM, hinders platelet aggregation, eosinophil activation, boosts calcium transit, anti-nephrotoxic.Formule :C28H29ClN4SCouleur et forme :SolidMasse moléculaire :489.07FLLRN
CAS :<p>FLLRN is a biologically active peptide serving as a PAR1-specific antagonist.</p>Formule :C31H51N9O7Couleur et forme :SolidMasse moléculaire :661.79Bosentan-d4
CAS :Bosentan-d4: deuterium version of Bosentan, competitive ET A/B antagonist, Ki: 4.7nM (ET A), 95nM (ET B) in human SMC.Formule :C27H25D4N5O6SMasse moléculaire :555.64BNP (1-21), Pro (Human)
CAS :BNP (1-21), Pro (Human) is a 21-amino acid peptide and a form of B-Type Natriuretic Peptide (BNP), a cardiac natriuretic hormone.Formule :C89H144N28O35Masse moléculaire :2166.26Anticancer agent 258
CAS :Anticanceragent 258 is an imidazo[1,2-B][1,2,4]triazole derivative that modulates nuclear receptor activity. It exhibits an EC50 of 63 nM for Nurr in N2A cells and an IC50 of 0.1 pM for Nur77 in HEK293 cells. Anticanceragent 258 is applicable in studies related to cancer, metabolic disorders, and neurological diseases.Formule :C17H12F2N4Couleur et forme :SolidMasse moléculaire :310.3Sar-[D-Phe8]-des-Arg9-Bradykinin
CAS :Potent bradykinin B1 agonist, EC50 = 9.02 nM, enzyme resistant, induces hypotension and angiogenesis.Formule :C47H66N12O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :975.11T-kinin
CAS :T-kinin (Ile-Ser-bradykinin) is a bradykinin-containing peptide utilized in inflammation research [1] [2].Formule :C59H89N17O14Masse moléculaire :1260.44(Asp28)-Glucagon (1-29) (human, rat, porcine)
CAS :"(Asp28)-Glucagon (1-29) (human, rat, porcine)" is an analog of glucagon with an aspartic acid (Asp) substitution at position 28, notably enhancing its aqueousFormule :C153H224N42O50SMasse moléculaire :3483.73[D-p-Cl-Phe6,Leu17]-VIP TFA
[D-p-Cl-Phe6,Leu17]-VIP TFA acts as a competitive and selective antagonist of the vasoactive intestinal peptide (VIP) receptor, exhibiting an IC50 of 125.8 nM.Formule :C150H240F3ClN44O44Masse moléculaire :3456.22Bombinakinin M
CAS :Potent, selective bradykinin receptor agonist 50x stronger than bradykinin, contracts guinea pig ileum muscle at EC50 4.0 nM.Formule :C100H159N31O24Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2179.55SFNGGP-NH2
CAS :SFNGGP-NH2 is a biologically active peptide that interacts with Protease-Activated Receptor 3 (PAR-3), a high-affinity thrombin receptor.Formule :C25H36N8O8Couleur et forme :SolidMasse moléculaire :576.6Corazonin
CAS :Corazonin, a neuropeptide in insects, regulates caste identity and behavior, mainly in workers/foragers.Formule :C62H83N17O19Couleur et forme :SolidMasse moléculaire :1370.42Wy 41747
CAS :Wy 41747 is a long-acting somatostatin analogue utilized in research of diabetes mellitus [1].Formule :C73H92N18O16S2Masse moléculaire :1541.75PG106 TFA
PG106 TFA is a potent hMC3 antagonist (IC50=210 nM), inactive at hMC4 (EC50=9900 nM) and hMC5 receptors.Formule :C53H70F3N13O11Couleur et forme :SolidMasse moléculaire :1122.2α-Helical CRF(9-41) TFA
α-Helical CRF(9-41) TFA acts as a competitive antagonist for the CRF2 receptor, possessing a binding constant (K B) of approximately 100 nM.Formule :C168H275F3N46O55S2Couleur et forme :SolidMasse moléculaire :3940.42[Des-Arg9]-Bradykinin acetate
CAS :[Des-Arg9]-Bradykinin acetate is a selective agonist of Bradykinin B1 receptor.Formule :C46H65N11O12Degré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :964.07Atriopeptin III (rat)
CAS :Atriopeptin III (rat) (ANP 127-150), a 24-amino acid atrial peptide, functions as a powerful vasodilator and natriuretic/diuretic agent, enhancing renalFormule :C107H165N35O34S2Masse moléculaire :2549.8Uroguanylin (human) TFA
Uroguanylin (human) (TFA) is the natural ligand for the guanylate cyclase C (GCC) receptor expressed in metastatic colorectal cancer tumors. In animal models of human colon cancer, Uroguanylin (human) (TFA) demonstrates antitumor activity.Couleur et forme :Odour SolidPAR 4 (1-6) (TFA)
PAR 4 (1-6) TFA (GYPGQV TFA), a hexapeptide derived from protease-activated receptor 4 (PAR 4), serves as a specific agonist for PAR 4.Formule :C28H41N7O9·xC2HF3O2Couleur et forme :SolidLY-53857 free base
CAS :LY-53857 free base is a bioactive chemical.Formule :C23H32N2O3Couleur et forme :SolidMasse moléculaire :384.518-iso-16-cyclohexyl-tetranor Prostaglandin E2
CAS :8-iso PGE2, a lipid peroxidation byproduct, has a synthetic variant, 8-iso-16-cyclohexyl-tetranor PGE2, unstudied pharmacologically.Formule :C22H34O5Couleur et forme :SolidMasse moléculaire :378.509Prolactin Releasing Peptide (1-31), human
CAS :Human Prolactin Releasing Peptide (1-31) is a potent GPR10 agonist; Ki values are 1.03 nM (human) and 0.33 nM (rat).Formule :C160H252N56O42SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :3664.15Moxonidine hydrochloride
CAS :Moxonidine Hydrochloride: selective I1 imidazoline receptor agonist, stronger than α2-AR; lowers blood pressure; central action.Formule :C9H13Cl2N5OCouleur et forme :SolidMasse moléculaire :278.14GHRF, mouse
CAS :GHRF (mouse), a mouse growth hormone-releasing factor, is a 44-amino acid peptide that promotes the synthesis and release of growth hormone [1].Fezolamine
CAS :Fezolamine: a new, non-tricyclic, oral antidepressant, selectively inhibits norepinephrine uptake over serotonin or dopamine.Formule :C20H23N3Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :305.42PF-4363467
CAS :PF-4363467 is a dopamine D3/D2 receptor antagonist that reduces opioid-seeking behavior without the side effects associated with D2 receptors. It has a Ki value of 3.1 nM for D3R and 692 nM for D2R.Formule :C22H30N2O3SCouleur et forme :SolidMasse moléculaire :402.55AD353
AD353 is a selective sigma-1 receptor ligand. It demonstrates high efficacy in models of capsaicin-induced allodynia and PGE2-induced mechanical hyperalgesia. Additionally, AD353 exhibits favorable pharmacokinetic properties.Formule :C23H30N2O2Couleur et forme :SolidMasse moléculaire :366.5Guanylin(human)
CAS :Peptide that activates gut guanylyl cyclase, secreted by GI mucosa, regulates water and electrolytes in gut and kidneys.Formule :C58H87N15O21S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1458.65GR 82334
CAS :Tachykinin NK1 receptor antagonist.Formule :C69H91N15O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1386.5717-TFM-PGF1α
CAS :17-TFM-PGF1α (Compound 8) is a saturated prostaglandin analog. It exhibits a high affinity and receptor selectivity for the human prostaglandin F receptor (hFP receptor), with an EC50 of 85 nM.Formule :C24H35F3O5Couleur et forme :SolidMasse moléculaire :460.53Fpl 14294
CAS :<p>Fpl 14294 is a novel CCK-8 agonist with effective intranasal anorectic activity in the rat.</p>Formule :C45H56N8O13S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1013.17Formoterol O-β-D-Glucuronide
CAS :Formoterol O-β-D-glucuronide is a metabolite of formoterol .Formule :C25H32N2O10Couleur et forme :SolidMasse moléculaire :520.535Velmupressin acetate
CAS :Potent, selective, short-acting peptidic V2R agonist; EC50: 0.07 nM (hV2R), 0.02 nM (rV2R).Formule :C44H64ClN11O10S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1006.63Neuropeptide Y (3-36) (human, rat)
CAS :Neuropeptide Y (3-36) is a Y2 receptor agonist that limits norepinephrine release, produced by DPP4 from NPY.Formule :C175H269N53O54SCouleur et forme :SolidMasse moléculaire :4011.5(Trp7,β-Ala8)-Neurokinin A (4-10)
CAS :(Trp7,β-Ala8)-Neurokinin A (4-10) is a potent neurokinin-3 (NK3) antagonist [1] .Formule :C41H57N9O10SCouleur et forme :SolidMasse moléculaire :868.01Endothelin-3, human, mouse, rabbit, rat
CAS :Endothelin-3, human, mouse, rabbit, rat , is a cyclic 21 amino acid peptide. It is an endogenous neuropeptide and potent vasoconstrictor.Formule :C121H168N26O33S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2643.04Eloralintide
CAS :Eloralintide (LY 3841136) is an AMYR agonist, anticipated for research in type 2 diabetes and obesity.Formule :C201H319N49O65S2Couleur et forme :SolidMasse moléculaire :4526.1Leukotriene B5
CAS :LTB5, an eicosapentaenoic acid metabolite via 5-LO, has varied bioactivities and enhances bullfrog lung strip contraction.Formule :C20H30O4Couleur et forme :SolidMasse moléculaire :334.456Saterinone
CAS :<p>Saterinone: PDE III inhibitor, α-1-adrenoceptor antagonist, vasodilator, used for acute chronic heart failure, IC50 2.3x10^-5 M.</p>Formule :C27H30N4O4Degré de pureté :98.23%Couleur et forme :SolidMasse moléculaire :474.554-hydroxy DiPT hydrochloride
CAS :4-hydroxy DiPT (hydrochloride) is a 5-HT2A agonist that can induce head twitch response (HTR) in mice, indicating its hallucinogenic potential. This compound holds promise for research into hallucinogens.Formule :C16H25ClN2OCouleur et forme :SolidMasse moléculaire :296.84Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate
CAS :Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate is an NPR-A agonist and ANP hormone. Carperitide increases cGMP levels and reduces the heart's workload.Formule :C129H207N45O41S3Degré de pureté :99.78%Couleur et forme :SoildMasse moléculaire :3140.5P2Y14R antagonist 3
<p>P2Y14R antagonist 3 (compound A) is an orally active P2Y14R antagonist with an IC50 of 23.60 nM and a Kd of 7.26 μM. It mitigates lung injury in mice induced by Lipopolysaccharides (LPS) and can be utilized in the study of inflammatory diseases.</p>Formule :C26H25N5O5Couleur et forme :SolidMasse moléculaire :487.51Spiroglumide
CAS :Spiroglumide, a CCKB-gastrin antagonist that inhibits dose-dependent pentagastrin-induced acid hypersecretion with an ID50 of 20.1 (8.67-46.4) mg / kg, could beFormule :C21H26Cl2N2O4Degré de pureté :98.23%Couleur et forme :SoildMasse moléculaire :441.35Δ8-THC methyl ether
CAS :Δ8-THC methyl ether (compound 3) demonstrates a strong docking score of -10.167 kcal/mol for the CB2 receptor. Additionally, Δ8-THC methyl ether exhibits antinociceptive activity in mice.Formule :C22H32O2Couleur et forme :SolidMasse moléculaire :328.49Afubiata
CAS :ADB-FUBIATA is a synthetic cannabinoid studied for its metabolic profile, along with AFUBIATA, CH-FUBIATA, and CH-PIATA. This in vitro analysis by Watanabe S, et al., examines these compounds, as published in "Arch Toxicol," 2023 Dec;97(12):3085-3094.Formule :C27H29FN2OCouleur et forme :SolidMasse moléculaire :416.53
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