GPCR/G-Protéine
Les inhibiteurs des GPCR/protéines G sont des composés qui ciblent les récepteurs couplés aux protéines G (GPCR) et les protéines G associées, qui jouent un rôle crucial dans la transmission des signaux de l'extérieur vers l'intérieur des cellules. Ces inhibiteurs sont essentiels pour étudier les voies de signalisation médiées par les GPCR, impliquées dans de nombreux processus physiologiques, y compris la perception sensorielle, la réponse immunitaire et la neurotransmission. Les inhibiteurs des GPCR sont également importants dans le développement de médicaments, car de nombreux agents thérapeutiques ciblent ces récepteurs. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de GPCR/protéines G de haute qualité pour soutenir vos recherches en pharmacologie, biologie cellulaire et domaines connexes.
Sous-catégories appartenant à la catégorie "GPCR/G-Protéine"
- récepteur 5-HT(1.025 produits)
- Récepteur d'adénosine(249 produits)
- Récepteur adrénergique(3.004 produits)
- Récepteur de la bombésine(35 produits)
- Récepteur de la bradykinine(61 produits)
- CXCR(155 produits)
- CaSR(34 produits)
- Récepteur cannabinoïde(217 produits)
- Cholécystokinine(1 produits)
- Récepteur de la dopamine(445 produits)
- Récepteur de l'endothéline(86 produits)
- Récepteur GNRH(84 produits)
- GPCR19(33 produits)
- GRK(33 produits)
- GTPase(23 produits)
- Récepteur du glucagon(192 produits)
- Hérisson/Smoothened(49 produits)
- Récepteur de l'histamine(385 produits)
- Récepteur LPA(21 produits)
- Récepteur de la mélatonine(26 produits)
- Récepteur OX(41 produits)
- Récepteur opioïde(326 produits)
- PAFR(14 produits)
- PKA(60 produits)
- Récepteur S1P(17 produits)
- SGLT(31 produits)
- Récepteur Sigma(46 produits)
Affichez 19 plus de sous-catégories
5970 produits trouvés pour "GPCR/G-Protéine"
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Spantide I TFA
Spantide I TFA is a selective NK1 antagonist (230 nM); much less for NK2 (8150 nM); it modulates cytokines to prevent corneal perforation.Formule :C77H109F3N20O15Couleur et forme :SolidMasse moléculaire :1611.81PAMP-12 (unmodified)
CAS :PAMP-12 (unmodified), an endogenous peptide and potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM), induces hypotension by inhibiting catecholamine release fromFormule :C77H118N24O15Couleur et forme :SolidMasse moléculaire :1619.91Adrenotensin (human)
CAS :Adrenotensin: human 153-185 fragment of Adrenomedullin precursor, a 52-amino acid peptide in CGRP hormone family.Formule :C143H224N42O43Couleur et forme :SolidMasse moléculaire :3219.56a-Helical Corticotropin Releasing Factor (12-41)
CAS :α-Helical CRF (12-41), a 30-aa analog, curbs CRF's ACTH-stimulating effect.Formule :C152H251N43O47S2Couleur et forme :SolidMasse moléculaire :3497.01Cortistatin 29
Cortistatin 29: neuropeptide, relieves neuropathic pain, binds SS receptors (IC50: 2.8-13.7 nM), anti-fibrotic.Formule :C161H242N46O41S2Couleur et forme :SolidMasse moléculaire :3539.77Calcitonin Gene Related Peptide (CGRP) II, rat TFA
Rat CGRP II TFA: potent vasodilator and CGRP receptor activator for cardiovascular research.
Formule :C165H268F3N51O52S2Couleur et forme :SolidMasse moléculaire :3919.33Neuropeptide S(Mouse) TFA
Neuropeptide S(Mouse) TFA: Endogenous NPSR agonist, EC50 3 nM, boosts Ca2+, activity, wakefulness, and lowers mouse anxiety.
Formule :C92H157F3N34O29Couleur et forme :SolidMasse moléculaire :2296.49Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin
CAS :Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin, a synthetic analog of vasopressin (AVP), acts as a weak agonist at the antidiuretic receptor but is a potentFormule :C45H63N15O11S2Couleur et forme :SolidMasse moléculaire :1054.21Dapiglutide
CAS :Dapiglutide (ZP7570) is a long-acting GLP-1R & GLP-2R dual agonist for SBS research.Couleur et forme :SolidBA 1 TFA
BA1 TFA agonizes BB receptors; binds BRS3, GRPR, NMBR with IC50s of 6, 0.4, 2.5 nM.Formule :C59H77F3N14O13Couleur et forme :SolidMasse moléculaire :1247.32ELA-11(human) TFA
ELA-11(human) TFA: apelin receptor agonist, K i =14 nM, inhibits cAMP, stimulates β-arrestin, from ELA-32 fragment.Formule :C60H91F3N16O15S2Couleur et forme :SolidMasse moléculaire :1397.58Cagrilintide
CAS :Cagrilintide is a long-acting amylin analogue acting as a dual agonist of the amylin receptor and calcitonin receptor, reducing body weight and food intake.Formule :C194H312N54O59S2Couleur et forme :SolidMasse moléculaire :4409.01(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin
CAS :(d(CH2)5[Tyr(Me)2, Dab5]AVP), a vasopressin V1a receptor-specific antagonist, demonstrates a pA2 value of 6.71 [1].Formule :C52H76N14O11S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1137.38GLP-1R Agonist DMB
CAS :GLP-1R Agonist DMB is an agonist of glucagon-like peptide 1 receptor (GLP-1R; KB = 26.3 nM for the recombinant human receptor).Formule :C13H15Cl2N3O2SDegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :348.25TRAP-6 amide
CAS :TRAP-6 amide is a PAR-1 thrombin receptor agonist peptide.Formule :C34H57N11O8Couleur et forme :SolidMasse moléculaire :747.899Protease-Activated Receptor-1, PAR-1 Agonist
CAS :Selective peptide agonist that mimics thrombin to activate PAR-1 receptor, enabling targeted receptor activation.Formule :C35H58N10O9Couleur et forme :SolidMasse moléculaire :762.91YFLLRNP
CAS :YFLLRNP is a biologically active peptide functioning as a partial agonist of PAR-1, selectively activating the G12/13 signaling pathway.Formule :C45H67N11O10Couleur et forme :SolidMasse moléculaire :922.08Tau conotoxin CnVA
CAS :Tau conotoxin CnVA, a small peptide found in the venom of Conus consors (cone snail), is a member of the T1 cone snail peptide superfamily. It demonstrates high selectivity for the somatostatin sst3 receptor with a Ki value of 1.5 µM. Tau conotoxin CnVA is unique as the only known toxin interacting with this subfamily of G protein-coupled receptors (GPCR). This compound is useful for research related to diseases associated with the sst3 receptor, such as pancreatic cancer or pituitary adenomas.Formule :C72H116N24O17S4Couleur et forme :SolidMasse moléculaire :1718.1HL2-m5
CAS :HL2-m5 is an inhibitor of the sonic hedgehog/patched (Shh/PTCH1) interaction, with a Kd for Shh of 170 nM. It effectively inhibits the activation of the Hedgehog signaling pathway and the transcription of Gli-controlled genes, with an IC50 of 230 nM.Formule :C70H101N15O24S3Couleur et forme :SolidMasse moléculaire :1632.83TRAP-6 amide TFA
CAS :TRAP-6 amide TFA is a PAR-1 thrombin receptor agonist peptide.Formule :C36H58F3N11O10Couleur et forme :SolidMasse moléculaire :861.922Levocarnitine propionate hydrochloride
CAS :Levocarnitine propionate hydrochloride (ST-261) is used for the treatment of the deterioration of renal function, congestive heart failure, and other diseases.Formule :C10H20ClNO4Degré de pureté :90% - 99.77%Couleur et forme :SolidMasse moléculaire :253.72α1A-AR Degrader 9c
CAS :α1A-AR Degrader 9c is a potent, selective, and reversible PROTAC degrader targeting the α1A adrenergic receptor (α1A-AR) with a DC50 of 2.86 μM.Formule :C38H43N11O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :829.82PSB-1114 triethylamine
PSB-1114 triethylamine is a potent, enzymatically stable, P2Y2 receptor agonist with a 134 nM EC50, exhibiting greater than 50-fold selectivity over P2Y4 (EC50Formule :C10H15F2N3O13P3S·xC6H15NDegré de pureté :98%Couleur et forme :SolidL-797,591 hydrochloride
L-797,591 HCl activates SSTR1, boosts p-ERK5 with AG1478, and enhances p38 phosphorylation, reversible by AG1478.Formule :C38H50ClN5O2Degré de pureté :98.65% - >99.99%Couleur et forme :SoildMasse moléculaire :644.30α-CGRP (mouse, rat) TFA
α-CGRP (mouse, rat) TFA, a neuropeptide belonging to the calcitonin gene-related peptide (CGRP) family, is predominantly located at neuromuscular junctions andFormule :C162H262N50O52S2·C2HF3O2Degré de pureté :98%Couleur et forme :SolidBetahistine mesylate
CAS :Betahistine mesylate (Extovyl), an H1 agonist and vasodilator, treats Meniere's disease and vascular headaches; risks with asthma/ulcers.Formule :C8H12N2·2(CH4O3S)Degré de pureté :98% - 99.85%Couleur et forme :CoaMasse moléculaire :328.4AZP-531
CAS :Azp-531 is a disacylated ghrelin used to improve blood sugar control and weight loss.Formule :C40H63N15O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :962.02BIMU 8
CAS :BIMU 8 is a selective agonist of 5-HT4 with EC50s of 18 nM, 77 nM, and 540 nM for wild-type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4.Formule :C19H27ClN4O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :378.9Ref: TM-T21946
1mg85,00€5mg168,00€10mg235,00€25mg394,00€50mg582,00€100mg827,00€500mg1.674,00€1mL*10mM (DMSO)175,00€Tirzepatide
CAS :Tirzepatide (LY-3298176) is a dual glucose-dependent polypeptide (GIP) (EC50=0.042 nM) and glucagon-like peptide-1 (GLP-1) (EC50=0.086 nM) receptor agonist.Formule :C225H348N48O68Degré de pureté :99.52% - 99.99%Couleur et forme :SolidMasse moléculaire :4813.45Emoghrelin
CAS :Emoghrelin, extracted from Heshouwu (Polygonum multiflorum), promotes the secretion of growth hormone by activating the ghrelin receptor [1].Formule :C24H22O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :518.42Endolide F
Endolide F (Compound 2) is a proline-containing lactone that serves as a moderate antagonist of the arginine vasopressin V1A receptor.Formule :C25H32N4O6Masse moléculaire :484.23218FFN246
CAS :FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation andFormule :C15H13FN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :256.27Myristoylated ARF6 (2-13)
Myristoylated ARF6 (2-13) inhibits the MyD88–ARNO–ARF6 signaling axis by inactivating ARF6.Formule :C74H128N16O18Masse moléculaire :1528.95925CI-988 hemihydrate
CI-988 hemihydrate (PD134308) is a potent and selective orally active CCK2R (cholecystokinin 2 receptor) antagonist, with an IC50 of 1.7 nM for mouse cortical CCK2. It is over 1600 times more selective for CCK2 than for CCK1 receptors. CI-988 hemihydrate exhibits anxiolytic and antitumor properties.Formule :C35H42N4O6H2OMasse moléculaire :632.321SPN009
SPN009 (Sequence 3) is a GLP-1 receptor (GLP-1 Receptor) agonist, with an EC50 of 2.84 nM, and improves type 2 diabetes in DB/DB mouse models.Formule :C191H299N45O59Masse moléculaire :4167.17798Cyclic AC253
Cyclic AC253 is an amylin receptor antagonist with an IC50 of 0.3 μM. It offers neuroprotective effects against Aβ toxicity and mitigates Aβ-induced impairments in hippocampal long-term potentiation. Additionally, Cyclic AC253 is capable of penetrating the blood-brain barrier.Formule :C126H202N42O40S2Masse moléculaire :3007.45049S1H
S1H is an analog of human growth hormone (hGH) and acts as an antagonist to the human growth hormone receptor (hGHR). It inhibits the interaction between hGH and hGHR and prevents the phosphorylation of STAT5 in cells treated with hGH.Formule :C94H141N23O27Masse moléculaire :2024.03673Azido-FTY720
CAS :Azido-FTY720 (azido-Fingolimod) is an analogue of FTY720, with an azido group for click chemistry reactions. FTY720 is an orally available S1P1R modulator .Formule :C19H32N4O2Couleur et forme :SolidMasse moléculaire :348.49Denikitug
Denikitug is a chimeric antibody of the IgG1κ type that targets CCR8, with its corresponding isotype control being HumanIgG1kappa, Isotype Control.Couleur et forme :Odour LiquidNPS ALX Compound 4a hydrochloride(1:1)
NPS ALX Compound 4a hydrochloride(1:1) is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM.Formule :C25H26ClN3O2SDegré de pureté :99.84%Couleur et forme :SoildMasse moléculaire :468.01Ref: TM-T12262L1
1mg38,00€5mg84,00€10mg113,00€25mg188,00€50mg273,00€100mg371,00€200mg494,00€1mL*10mM (DMSO)92,00€Cortistatin-8
CAS :ghrelin receptor antagonistFormule :C47H68N12O9S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1009.25U 67827E
CAS :U 67827E is a long-lasting cholecystokinin agonist. It acts by decreases food intake.Formule :C53H68N10O17SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1149.24AA 497 HCl
CAS :AA 497, a beta-2 agonist, suppresses Ca spikes.Formule :C14H22ClNO3Couleur et forme :SolidMasse moléculaire :287.78Anticancer agent 258
CAS :Anticanceragent 258 is an imidazo[1,2-B][1,2,4]triazole derivative that modulates nuclear receptor activity. It exhibits an EC50 of 63 nM for Nurr in N2A cells and an IC50 of 0.1 pM for Nur77 in HEK293 cells. Anticanceragent 258 is applicable in studies related to cancer, metabolic disorders, and neurological diseases.Formule :C17H12F2N4Couleur et forme :SolidMasse moléculaire :310.3Cortagine
Potent CRF1 agonist, EC50 = 0.18 nM in rats. Exhibits in vivo anxiolytic and antidepressant effects; reduces mouse defensive behavior.Formule :C192H323N55O63SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4442.06RS 18286
CAS :RS 18286 is a LHRH antagonist.Formule :C74H101Cl2N17O14Couleur et forme :SolidMasse moléculaire :1523.6Abediterol napadisylate
CAS :Abediterol napadisylate is a novel long-acting β2-agonist in persistent asthma that is efficacy, safe, and tolerable.Formule :C60H68F4N4O14S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1209.32Vapiprost
CAS :Vapiprost is an antagonist of the thromboxane receptor and a prostaglandin receptor.Formule :C30H39NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.64Clopidogrel-related Compound B hydrochloride
CAS :Clopidogrel Related Compound B is a useful organic compound for research related to life sciences.Formule :C16H17Cl2NO2SCouleur et forme :SolidMasse moléculaire :358.28Tiaspirone hydrochloride
CAS :Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity and influences the electrophysiological activity of dopaminergic neurons.Formule :C24H33ClN4O2SDegré de pureté :99.87%Couleur et forme :SoildMasse moléculaire :477.06RC-3095
CAS :RC-3095, a selective GRPR antagonist, has been shown to have anti-inflammatory properties in different models of inflammation.Formule :C56H79N15O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1106.32PSB-22269
PSB-22269 is identified as a GPR17 antagonist with a Ki value of 8.91 nM. It exhibits significant inhibitory effects in cAMP and G protein activation assays. Molecular docking studies indicate that the binding site of PSB-22269 includes positively charged arginine residues and a hydrophobic pocket. PSB-22269 promotes myelin regeneration strategies, offering potential for multiple sclerosis research.Formule :C26H21NO6Couleur et forme :SolidMasse moléculaire :443.45JNJ-10181457 (hydrochloride)
CAS :JNJ-10181457 (hydrochloride) is a non-imidazole H3 receptor antagonist that is brain-penetrating and selective, increasing NE and acetylcholine concentrationsFormule :C20H30Cl2N2OCouleur et forme :SolidMasse moléculaire :385.37OXA(17-33)
CAS :Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.Formule :C79H125N23O22Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1749Oxmetidine FA
Oxmetidine FA is an orally available specific histamine H2 receptor antagonist with antiulcerogenic properties.Formule :C20H23N5O5SDegré de pureté :97.34%Couleur et forme :SoildMasse moléculaire :445.49CRF(6-33)(human)
CAS :CRFBP inhibitor peptide; blocks CRF, reduces weight gain, boosts activity in obese rats.Formule :C141H231N41O43SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :3220.68Lys-Bradykinin
CAS :Endogenous bradykinin receptor agonistFormule :C56H85N17O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1188.38[Nle11]-Substance P
CAS :'[Nle11]-Substance P is a gut and brain peptide, resisting methionine oxidation and causing excitatory neural effects.'
Formule :C64H100N18O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1329.59MLS1082
CAS :MLS1082 is a D1-like dopamine receptor (D1R) orthosteric modulatothat stimulates G-protein signaling upon dopamine activation for neurodegenerative disorders.Formule :C24H23N3O2Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :385.46MD01-67
CAS :MD01-67 is a macrocyclic compound selectively targeting the neurotensin 2 receptor (NTS2), with a Ki of 2.9 nM. It exhibits analgesic activity and reduces tactile hypersensitivity in rat models of acute, sustained, and chronic inflammatory pain.Formule :C37H58N8O8Couleur et forme :SolidMasse moléculaire :742.91AC-178335
CAS :AC-178335: SRIF antagonist, Ki=172 nM, inhibits SRIF's adenylate cyclase effects (IC50=5.1 µM), triggers GH release in rats.Formule :C49H63N13O7Couleur et forme :SolidMasse moléculaire :946.11Acrinor
CAS :Acrinor is a adrenergic beta receptor agonist.Formule :C35H46Cl2N10O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :805.72Prostaglandin K1
CAS :Prostaglandin K1 (compound 46) is a structurally modified prostanoid analog with an EC50 and Ki of 2800 nM for the EP1 receptor.Formule :C20H32O5Couleur et forme :SolidMasse moléculaire :352.47ADTN
CAS :ADTN is an agonist of the dopamine receptor.Formule :C10H13NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :179.22Ono 3708
CAS :Ono-3708 is a potent antagonist of the thromboxane A2/prostaglandin endoperoxide receptor in vitro and in vivo.Formule :C23H37NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :391.54Calcitonin (8-32), salmon
CAS :Calcitonin (8-32), salmon: selective amylin receptor antagonist, regulates calcium/phosphorus, thyroid origin, 32-aa peptide.Formule :C119H198N36O37Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2725.06Anthramycin
CAS :Anthramycin: a PBD family antibiotic with antitumor effects and CNS cholecystokinin antagonist properties in mice.Formule :C16H17N3O4Couleur et forme :SolidMasse moléculaire :315.32Fluphenazine free base
CAS :Flufenazine: antipsychotic for schizophrenia, blocks dopamine D2 receptors, reduces hallucinations and delusions.Formule :C22H26F3N3OSCouleur et forme :SolidMasse moléculaire :437.52Albiglutide Fragment
CAS :Albiglutide fragment is a 30-amino-acid sequence of modified human GLP-1 (fragment 7-36).Formule :C148H224N40O45Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3283.6FR190997
CAS :FR190997 is an agonist of bradykinin B2 receptor.Formule :C37H33Cl2N5O5Couleur et forme :SolidMasse moléculaire :698.59RFRP-1(human)
CAS :Endogenous NPFF agonist with EC50 of 0.0011 nM (NPFF2) and 29 nM (NPFF1); reduces cardiac function and raises prolactin in rats. GnIH homolog.Formule :C67H101N19O14SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1428.72GLP-1R Antagonist 1
CAS :GLP-1R Antagonist 1 is an orally active, CNS penetrant and non-competitive glucagon-like peptide 1 receptor (GLP-1R) antagonist (IC50: 650 nM).Formule :C16H11ClF6N4O2Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :440.73TGR5 agonist 6
CAS :Compound 22b, also known as TGR5 agonist 6, is a non-systemic, intestine-targeted TGR5 agonist that demonstrates significant and sustained blood glucose-lowering effects with an acceptable safety profile.Formule :C42H48Cl2N6O6Couleur et forme :SolidMasse moléculaire :803.77Khusimol
CAS :Khusimol is a vasopressin V1a receptors non-peptide ligand that acts by inhibiting the binding of vasopressin.Formule :C15H24ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :220.35Pobilukast
CAS :Pobilukast (SKF 104353) is a cysteinyl leukotriene receptor antagonist that can be used to study limiting myocardial injury in MI/R rats.Formule :C26H34O5SDegré de pureté :99.65% - 99.84%Couleur et forme :SolidMasse moléculaire :458.61Glucagon-like peptide 1 (1-37), human
CAS :Human GLP-1 (1-37) is a potent GLP-1 receptor agonist without impact on rat food intake or insulin secretion.Formule :C186H275N51O59Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4169.48Metaraminol
CAS :Metaraminol is a sympathomimetic agent that acts predominantly at alpha-1 adrenergic receptors.Formule :C9H13NO2Couleur et forme :SolidMasse moléculaire :167.21GRL093-22
GRL093-22 is an effective and selective inhibitor of G protein-coupled receptor kinases (GRK), with IC50 values of 60 nM for GRK5 and 40 nM for GRK6. It shows potential for research in heart failure and multiple myeloma.Formule :C33H29FN6O3Couleur et forme :SolidMasse moléculaire :576.625-HT2A receptor agonist-6
CAS :5-HT2A receptor agonist-6 (compound 47) is a selective agonist of the 5-HT2A receptor with a pEC50 value of 6.58.Formule :C18H19N3O3Couleur et forme :SolidMasse moléculaire :325.36BMY-14802
CAS :BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.Formule :C18H22F2N4ODegré de pureté :99.84%Couleur et forme :SoildMasse moléculaire :348.39Ref: TM-T67739
2mg35,00€5mg52,00€10mg90,00€25mg164,00€50mg259,00€100mg383,00€200mg545,00€1mL*10mM (DMSO)58,00€TGR5 agonist 7
TGR5 agonist 7 (Compound 22-Na) is an intestine-restricted, orally active agonist of the G protein-coupled bile acid receptor TGR5 (GPBAR1 or GPR131) with an EC50 of less than 1 μM. In mouse models, it demonstrates blood glucose-lowering effects, making it useful for diabetes research.Formule :C37H59N2NaO9SCouleur et forme :SolidMasse moléculaire :730.931a,1b-dihomo Prostaglandin E1
CAS :1a,1b-dihomo Prostaglandin E1 is a class of prostaglandin compounds.Formule :C22H38O5Couleur et forme :SolidMasse moléculaire :382.5414-Hydroxy MPT
CAS :4-Hydroxy MPT (4-OH-MPT) is a serotonin-active compound that acts as an agonist for 5-HT2A and 5-HT2B receptors, with EC50 values of 3.82 nM and 3.4 nM, respectively.Formule :C14H20N2OCouleur et forme :SolidMasse moléculaire :232.32Lysophosphatidic acid
CAS :Lysophosphatidic acid is a bioactive chemical.Formule :C21H41O7PCouleur et forme :SolidMasse moléculaire :436.52exo-Tetrahydrocannabivarin
CAS :exo-Tetrahydrocannabivarin (Compound 12) is an analog of Δ9,11-THC. It weakly binds to cannabinoid receptors (CB) with an IC50 of 1.4 μM. In mice, exo-Tetrahydrocannabivarin exhibits activity related to both motor function and analgesia.Formule :C19H26O2Couleur et forme :SolidMasse moléculaire :286.41Human growth hormone-releasing factor
CAS :GHRH from the hypothalamus prompts the pituitary to produce/release GH by attaching to the GHRHR.Formule :C215H358N72O66SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :5039.65FK 224
CAS :FK 224 is an antagonist of tachykinin receptor.Formule :C54H72N8O13Couleur et forme :SolidMasse moléculaire :1041.213ent-Prostaglandin E2
CAS :Enzymatic PGE2 is optically pure; radical peroxidation makes it racemic. In oxidative stress, rac-PGE2 forms via 15-E2t-isoprostane.
Formule :C20H32O5Couleur et forme :SolidMasse moléculaire :352.47117-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide
CAS :Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.
Formule :C26H36F3NO4Couleur et forme :SolidMasse moléculaire :483.572Nolomirole
CAS :Nolomirole is a dopamine receptor agonist that reduces symptoms of congestive heart failure caused by monoclinine.Formule :C19H27NO4Couleur et forme :SolidMasse moléculaire :333.42GW-328267
CAS :GW-328267 is an agonist of the adenosine A2 receptor.Formule :C21H26N10O4Couleur et forme :SolidMasse moléculaire :482.5Carazolol-d7
CAS :Carazolol-d7 is the deuterium-labeled isotope of Carazolol, commonly used in pharmacokinetic studies to investigate the metabolic pathways of Carazolol.Formule :C18H22N2O2Couleur et forme :SolidMasse moléculaire :305.42Albenatide
CAS :Albenatide is a modified analog of exendin 4 conjugated to recombinant human albumin.
Formule :C26H47N7O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :633.761-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid
CAS :1-(4-Fluorobenzyl)-1H-indazole-3-carboxylic acid (Compound 31) is a metabolite of AB-FUBINACA. It acts as an MRGPRX4 antagonist with an IC50 greater than 2.5 μM.Formule :C15H11FN2O2Couleur et forme :SolidMasse moléculaire :270.26LysoPalloT-NH-amide-C3-ph-m-O-C11
CAS :LysoPalloT-NH-amide-C3-ph-m-O-C11 is an agonist of the GPR174 receptor with an EC50 value of 34 nM.Formule :C27H47N2O9PCouleur et forme :SolidMasse moléculaire :574.64Afubiata
CAS :ADB-FUBIATA is a synthetic cannabinoid studied for its metabolic profile, along with AFUBIATA, CH-FUBIATA, and CH-PIATA. This in vitro analysis by Watanabe S, et al., examines these compounds, as published in "Arch Toxicol," 2023 Dec;97(12):3085-3094.Formule :C27H29FN2OCouleur et forme :SolidMasse moléculaire :416.53Nocistatin(human)
CAS :Blocker of nociceptin-induced allodynia and hyperalgesiaFormule :C149H238N42O53S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3561.936α-Prostaglandin I1
CAS :6α-Prostaglandin I1 (6α-PGI1) is a stable Prostaglandin I2 (PGI2) analog resistant to hydrolysis in aqueous solutions.Formule :C20H34O5Couleur et forme :SolidMasse moléculaire :354.487(+)-ORM-10921
CAS :(+)-ORM-10921 is a conformation of ORM-10921 and can be used in chemical synthesis studies.Formule :C18H23NO2Degré de pureté :99.23%Couleur et forme :SoildMasse moléculaire :285.38Ularitide
CAS :Ularitide is a 32-amino acid peptide from ANP prohormone, resistant to dog kidney cortex peptidase.Formule :C145H234N52O44S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3505.97PSA1 (141-150)
CAS :This Prostate Specific Antigen 1 peptide was used in the immunotherapy of cancer experiments.Formule :C55H93N13O13SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1176.47Galanin (1-19), human
CAS :Galanin (1-19), human: a fragment of GAL neuropeptide influencing hormone release, pain response, and eating behavior.Formule :C89H130N26O25Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1964.14isomer-Cilansetron
CAS :isomer-Cilansetron is an isomer of Cilansetron.Formule :C20H21N3ODegré de pureté :99.92% - 99.96%Couleur et forme :SoildMasse moléculaire :319.41,8-Cineole
CAS :Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.Formule :C10H18ODegré de pureté :97.44% - 97.44%Couleur et forme :SolidMasse moléculaire :154.2516,16-dimethyl Prostaglandin F2α
CAS :16,16-dimethyl Prostaglandin F2α can be used in related research in the field of life sciences. Its product number is T37993 and CAS number is 39746-23-1.Formule :C22H38O5Couleur et forme :SolidMasse moléculaire :382.541BMS-604992 dihydrochloride
CAS :BMS-604992 dihydrochloride is a selective GHSR agonist with high affinity (Ki=2.3 nM) and potent activity (EC50=0.4 nM), stimulating rodent appetite.Formule :C24H33Cl2N7O5Couleur et forme :SolidMasse moléculaire :570.47Neuronostatin-13 (human)
CAS :Neuronostatin-13: human-conserved, 13-amino-acid peptide with amidated C-terminus.Formule :C64H110N20O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1415.681-Octadecyl Lysophosphatidic Acid
CAS :1-Octadecyl LPA, an LPA analog with stearic acid at sn-1, has strong platelet aggregation (EC50=9 nM) via G protein receptors.Formule :C21H45O6PCouleur et forme :SolidMasse moléculaire :424.559DOTA-EB-TATE
DOTA-EB-TATE is formed by combining the SST peptide derivative DOTA-octreotate with an Evans blue analog (EB). This peptide drug conjugate (PDC) enhances the pharmacokinetics of SSTR2 analogs and reduces PRRT toxicity. Additionally, DOTA-EB-TATE serves in the synthesis/research of radiopharmaceutical conjugates (RDC).Formule :C105H133N21O30S5Couleur et forme :SolidMasse moléculaire :2329.63Prolactin-Releasing Peptide (12-31), rat
CAS :Prolactin-Releasing Peptide (12-31), rat, a fragment of PrRP, exhibits high affinity for GPR10 receptors and stimulates calcium mobilization in CHOK1 cellsFormule :C104H158N32O26Couleur et forme :SolidMasse moléculaire :2272.57Neuropeptide Y (1-24) (human)
CAS :Neuropeptide Y (1-24) inhibits rat vas deferens twitch and activates NMDA-induced neurons in rat hippocampus.Formule :C116H170N30O40SCouleur et forme :SolidMasse moléculaire :2656.83Onvitrelin ucalontide
CAS :Onvitrelin ucalontide is a LHRH analogue with anticancer effect; halts breast, ovarian, and prostate tumors in mice.Formule :C163H243N43O32Couleur et forme :SolidMasse moléculaire :3316.94Lintitript
CAS :Lintitript (SR 27897) is a selective antagonist of CCK1 with EC50s of 6 nM and 200 nM for CCK1 and CCK2. The Ki value is 0.2 nM for CCK1.Formule :C20H14ClN3O3SDegré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :411.86Ref: TM-T15759
1mg50,00€2mg71,00€5mg105,00€10mg160,00€25mg344,00€50mg645,00€100mg864,00€1mL*10mM (DMSO)117,00€Sulamserod
CAS :Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular relatedFormule :C19H28ClN3O5SDegré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :445.96Contulakin G
CAS :Contulakin G: O-glycosylated neurotensin, weak neurotensin receptor agonist, strong antinociceptive.Formule :C88H140N20O37Masse moléculaire :2070.1715(S)-Latanoprost
CAS :15(S)-Latanoprost, a latanoprost analog with inverted hydroxyl at C-15, has an IC50 of 24 nM and reduces IOP by 1 mmHg at 3 μg.Formule :C26H40O5Couleur et forme :SolidMasse moléculaire :432.59Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP (1-7)-GRF (8-27)
CAS :Acetyl-(D-Phe2,Lys15,Arg16,Leu27)-VIP(1-7)-GRF(8-27) is a selective antagonist [1] for the vasoactive intestinal peptide 1 (VIP 1) receptor.Formule :C150H246N44O38Couleur et forme :SolidMasse moléculaire :3273.83[D-Phe2,6, Pro3]-LH-RH
CAS :[D-Phe2,6, Pro3]-LH-RH is a potent antagonist of luteinizing hormone-releasing hormone (LHRH).Formule :C59H80N14O13Couleur et forme :SolidMasse moléculaire :1193.35(Leu31,Pro34)-Peptide YY (human)
CAS :(Leu31,Pro34)-Peptide YY (human) is a derivative of Peptide YY, acting as a potent and selective Y1 receptor agonist with a dissociation constant (KD) of 1.0 nMFormule :C195H296N54O56Couleur et forme :SolidMasse moléculaire :4292.75CCK (27-33) (non-sulfated)
CAS :CCK (27-33), a non-sulfated peptide, inhibits [3H]naloxone binding (IC50=4uM) and guinea pig ileum contractions (IC50=17uM), reversed by naloxone.Formule :C45H57N9O10S2Couleur et forme :SolidMasse moléculaire :948.12Oxopurpureine
CAS :Oxopurpureine, classified as an oxoaporphine compound, functions to inhibit plant pathogens.Formule :C21H19NO6Couleur et forme :SolidMasse moléculaire :381.38Thrombostatin cont-1
CAS :Thrombostatin cont-1, an analogue of the bradykinin metabolite thrombostatin, has been shown to reduce platelet activation in the canine carotid arteryFormule :C87H142N34O29S2Masse moléculaire :2192.4Endothelin 1 (swine, human) (TFA)
CAS :Synthetic human/swine Endothelin 1 (TFA) peptide; a potent vasoconstrictor acting on ET A and ET B receptors.Formule :C111H160F3N25O34S5Masse moléculaire :2605.93Dabelotine, (S)-
CAS :Dabelotine, (S)- is the S-isomer of Dabelotine. Dabelotine is an adrenergic agonist used in the study of dementia.Formule :C15H22N2O2Couleur et forme :SolidMasse moléculaire :262.35Pegapamodutide
CAS :Pegapamodutide (LY-2944876) is a dual glucagon-GLP-1 receptor agonist utilized in research concerning type 2 diabetes and obesity [1].Couleur et forme :SolidQWF acetate
QWF acetate is a Substance P antagonist peptide that specifically inhibits the binding to its receptor, NK1, and inhibits the activation of MRGPRX2.
Formule :C40H47N5O10Degré de pureté :96.65%Couleur et forme :SolidMasse moléculaire :757.845-trans Latanoprost
CAS :Latanoprost, an F-series prostaglandin analog for ocular hypertension, has a 5-trans isomer used as an analytical standard.Formule :C26H40O5Couleur et forme :SolidMasse moléculaire :432.601Bucindolol Formate
Bucindolol is a β1-adrenergic blocker with sympathomimetic activity, used in heart failure research.Formule :C23H27N3O4Degré de pureté :99.76% - 99.88%Couleur et forme :SolidMasse moléculaire :409.48SAG dihydrochloride
CAS :SAG dihydrochloride: potent Smo agonist, activates Hedgehog pathway, counters Cyclopamine. EC50=3 nM, Kd=59 nM.Formule :C28H30Cl3N3OSDegré de pureté :99.57%Couleur et forme :SoildMasse moléculaire :562.98Ritobegron HCl
CAS :Ritobegron (KUC-7483), a β3-adrenergic agonist, targets human β-AR effectively and is highly selective for rat bladder.Formule :C23H32ClNO5Couleur et forme :SolidMasse moléculaire :437.96(±)-PPCC
CAS :(±)-PPCC (oxalate) is a sigma-1 agonist that interacts with sigma-1 receptors (Ki=1.5 nM).Formule :C24H29NO3Couleur et forme :SolidMasse moléculaire :379.49PT-129
PT-129 is a PROTAC degrader targeting the NTF2 domain of G3BP1/2, degrading stress granules in stressed cells, suppressing proliferation.Formule :C46H48N8O12SCouleur et forme :SolidMasse moléculaire :936.98VIP(Guinea pig) TFA
Vasoactive Intestinal Peptide (VIP) Guinea pig TFA, a trophic and mitogenic factor, promotes growth in cultured whole embryos and acts as a gastrointestinalCouleur et forme :Odour SolidMMC(TMZ)-TOC
MMC(TMZ)-TOC exhibits a high binding affinity and selectivity for somatostatin receptor subtype 2 (SSTR2). It is designed to target and deliver TMZ specifically to SSTR2-positive tumor cells. MMC(TMZ)-TOC is applicable for cancer research.Formule :C72H98N20O19S2Masse moléculaire :1610.67585β-Corticotropin (swine)
CAS :β-Corticotropin (swine), a synthetic analog of the peptide hormone corticotropin (ACTH), induces steroid release [1] [2].Couleur et forme :SolidAdrenocorticotropic Hormone (ACTH) (1-10), human
CAS :ACTH (1-10), human: a weak α-MSH mimic at high doses (100-1000 nM), derived from adrenocorticotropin.Formule :C59H78N16O16SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1299.41ACTH (1-14) (TFA)
ACTH (1-14) (TFA) is a regulatory fragment of adrenocorticotropin, specifically involved in the control of cortisol and androgen synthesis [1].Formule :C79H110F3N21O22SMasse moléculaire :1794.9Prostaglandin E3
CAS :Prostaglandin E3 (PGE3) is an eicosapentaenoic acid (EPA) derivative with anti-inflammatory and anti-tumor activity, and shows anti-proliferative effects.Formule :C20H30O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :350.45Cetirizine D8 dihydrochloride
CAS :Cetirizine D8 dihydrochloride is a deuterated H1-antihistamine with long-acting effects.Formule :C21H26Cl2N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :433.4BQ-123 TFA
BQ-123 TFA: Potent ETA antagonist, IC50 = 7.3 nM, Ki = 25 nM, inhibits ET-1 cell proliferation, lowers rat BP.Formule :C33H43F3N6O9Couleur et forme :SolidMasse moléculaire :724.72Gastrin-Releasing Peptide, human
CAS :Gastrin-releasing peptide, released by vagal fibers, stimulates stomach G cells to secrete gastrin, affecting acid secretion and gut motility.Formule :C130H204N38O31S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2859.38JKC363
CAS :MC4 receptor antagonist; IC50: 0.5 nM (MC4), 44.9 nM (MC3). Blocks α-MSH, reduces TRH, food intake, and pain.
Formule :C69H91N19O16S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1506.72Big endothelin-1 (rat 1-39)
CAS :Big endothelin-1 (rat 1-39), a 39-residue peptide, induces a diuretic and natriuretic response in conscious Sprague-Dawley rats and elevates blood pressure inCouleur et forme :SolidBrain Natriuretic Peptide-45, mouse
CAS :Mouse BNP-45, a heart-derived peptide, lowers blood pressure and increases sodium excretion.TH023
TH023 is an inhibitor of the TLR4 signaling pathway, specifically targeting the formation of TLR4 homodimers. In HEK-Blue hTLR4 cells, TH023 suppresses the secretion of embryonic alkaline phosphatase with an IC50 of 0.354 μM and inhibits NO expression in RAW264.7 cells, with an IC50 of 1.61 μM. Additionally, TH023 inhibits the activation of NF-κB and reduces the nuclear translocation of NF-κB p65. The compound demonstrates anti-inflammatory effects in a mouse model of LPS-induced acute sepsis and improves lung injury in mice.Formule :C22H21ClF2N4OCouleur et forme :SolidMasse moléculaire :430.883D-Monophosphoryl Lipid A-5 triethylamine
3D-Monophosphoryl Lipid A-5 (3D-MPLA-5) triethylamine is a TLR agonist that acts as an adjuvant for vaccines, enhancing their immunogenicity.Formule :C88H170N3O20PMasse moléculaire :1621.27CCR2 antagonist 1
CAS :CCR2 antagonist 1 is a high-affinity and long-residence-time antagonist of CCR2 (Ki: 2.4 nM).Formule :C28H32BrF3N2OCouleur et forme :SolidMasse moléculaire :549.47Wy 41747
CAS :Wy 41747 is a long-acting somatostatin analogue utilized in research of diabetes mellitus [1].Formule :C73H92N18O16S2Masse moléculaire :1541.75PNMT-IN-1
PNMT-IN-1 (inhibitor 4) is a selective second generation inhibitor [1] of phenylethanolamine N-methyltransferase (PNMT), exhibiting a Ki value of 1.2 nM and anCouleur et forme :Odour Solidα-helical CRF 9-41 acetate
α-helical CRF 9-41 acetate is a competitive antagonist of CRF2 (KB = 100 nM) and a partial agonist of CRF1 (EC50 = 140 nM).
Degré de pureté :96.60%Couleur et forme :SolidMasse moléculaire :#N/ARef: TM-TP2048L
1mg208,00€5mg500,00€10mg672,00€25mg1.017,00€50mg1.359,00€100mg1.853,00€200mg2.498,00€Jmv 167
CAS :Jmv 167 is an antagonist of the Cholecystokinin receptor.Formule :C51H68N8O14SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1049.21L-770644 dihydrochloride
CAS :L-770644 dihydrochloride is a potent and selective agonist of the human beta3 adrenergic receptor.Formule :C30H38ClN7O4SCouleur et forme :SolidMasse moléculaire :628.19APJ receptor agonist 10
CAS :APJ receptor agonist 10 (Compound I choline salt) modulates the activity of the APJ receptor, making it useful for pulmonary hypertension research. Compared to its free form, this compound exhibits improved bioavailability.Formule :C26H36N7O6SCouleur et forme :SolidMasse moléculaire :574.67Ecraprost
CAS :Ecraprost is used as a prodrug of prostaglandin E1.Formule :C28H48O6Couleur et forme :SolidMasse moléculaire :480.68LHRH, Ala(6)-
CAS :LHRH, Ala(6)- is a synthetic luteinizing hormone-releasing hormone agonist agent.Formule :C56H77N17O13Couleur et forme :SolidMasse moléculaire :1196.32Neurokinin B acetate(86933-75-7 free base)
Neurokinin B acetate, a tachykinin, interacts with NK1R, NK2R, & NK3R receptors to exert biological effects.Formule :C57H83N13O16S2Degré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :1270.48ALD1910
ALD1910 is a humanized monoclonal antibody targeting PACAP38 and PACAP27. It inhibits PACAP signaling through pituitary adenylate cyclase-activating peptide type I receptor (PAC1-R), vasoactive intestinal peptide receptor 1 (VPAC1-R), and VPAC2-R. ALD1910 recognizes a non-linear epitope within PACAP and prevents its binding to cell surfaces. It is useful for studying PACAP-mediated migraines.Couleur et forme :Odour LiquidMDL 19301
CAS :MDL 19301 is a nonsteroidal, anti-inflammatory agent.Formule :C15H21NS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :279.46Wy 43657
CAS :Wy 43657 is a gonadorelin antagonist.Formule :C71H86N14O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1343.554A-286501
CAS :A-286501: Oral adenosine kinase inhibitor, IC50=0.47 nM, reduces pain via non-opioid, non-NSAID ADO receptors.Formule :C11H14BrN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :328.17S 16474
CAS :S 16474 is an antagonist of Neurokinin-1 Receptor.Formule :C44H48N6NaO8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :811.892Pneumadin, rat
CAS :Rat Pneumadin (PNM), a decapeptide, stimulates AVP release, exerting strong antidiuretic effects in animals with an active AVP system.Formule :C47H74N12O15Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1047.178CAY10580
CAS :CAY10580 is a potent and selective prostaglandin EP 4 receptor agonist ( K i =35 nM).Formule :C19H35NO4Couleur et forme :SolidMasse moléculaire :341.49Avorelin
CAS :Avorelin, a luteinizing hormone releasing hormone (LH-RH) agonist, is used potentially for the treatment of prostate.Formule :C65H85N17O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1296.48RGS2-Galpha-q interaction-IN-1
RGS2–Galpha-q interaction-IN-1 (Compound AJ-3) is an inhibitor of the RGS2-Galpha-q interaction. It inhibits the growth of cancer cell lines that express RGS2 and has anti-cell migration properties.Formule :C30H30ClN7O3Couleur et forme :SolidMasse moléculaire :572.06Oxaprotiline hydrochloride
CAS :Oxaprotiline hydrochloride is an antidepressant.Formule :C20H24ClNODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.86Apelin-12 acetate
Apelin-12 acetate possesses a high affinity to orphan receptor APJ receptor.Formule :C66H107N21O16SDegré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :1482.75Ref: TM-T39823L
1mg128,00€5mg172,00€10mg269,00€25mg429,00€50mg610,00€100mg820,00€1mL*10mM (DMSO)430,00€LRGILS-NH2
CAS :LRGILS-NH2, reverse sequence of SLIGRL-NH2, is a control peptide for PAR2, affecting gut transit.Formule :C29H56N10O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :656.82Nebokitug
Nebokitug is a humanized IgG1κ antibody targeting CCL24, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Couleur et forme :Odour LiquidPF-4348235 HCl
PF-4348235 HCl (β2AR/M-receptor agonist-2 HCl) is a muscarinic M3 receptor antagonist (Ki: 0.73 nM) and β2 adrenergic receptor agonist (MABA, EC50: 3.7 nM). PF-4348235 HCl is also a bronchial BM213 acetate is a bronchodilator used to study cardiovascular and respiratory diseases such as chronic obstructive pulmonary disease (COPD).
Formule :C36H50Cl2N4O7SDegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :753.78DSP-1053
CAS :Dsp-1053 is a powerful SERT (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonizing activity.Formule :C26H32BrNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.44L 366811
CAS :L 366811 is a potent oxytocin antagonist.Formule :C43H56N8O6Couleur et forme :SolidMasse moléculaire :780.95Plozalizumab
CAS :Plozalizumab (MLN-1202) is a humanized selective and potent anti-CCR2 antibody.Plozalizumab has antitumor activity.Plozalizumab is used in the study of
Degré de pureté :96.4%Couleur et forme :LiquidMasse moléculaire :146.02 kDaNeocarzinostatin
CAS :Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :N/A(Ala13)-Apelin-13 TFA
'(Ala13)-Apelin-13 TFA acts as a potent antagonist of the apelin receptors (APJ) and impedes gastric motility via the vagal cholinergic pathway [1].'Formule :C63H107N23O16S·xC2HF3O2Couleur et forme :SolidMasse moléculaire :1474.73 (free acid)PAR-4 Agonist Peptide, amide
CAS :PAR-4 Agonist Peptide, amide (AY-NH2) is an agonist of proteinase-activated receptor-4 (PAR-4).Formule :C34H48N8O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :680.7912-epi Leukotriene B4
CAS :LTB4 is made enzymatically (12(R)-specific) and non-enzymatically (6-trans-12-epi mix). 12-epi LTB4 has low receptor activity.Formule :C20H32O4Couleur et forme :SolidMasse moléculaire :336.472GLP-1 moiety from Dulaglutide
GLP-1 moiety from Dulaglutide is a 31-amino acid fragment of Dulaglutide which is a glucagon-like peptide 1 receptor (GLP-1) agonist.Formule :C149H221N37O49Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3314.62(S)-Azelastine hydrochloride
CAS :(S)-Azelastine HCl, an antihistamine, reduces H1R, M1R, M3R levels and inhibits HNEpC growth.Formule :C22H25Cl2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :418.36Cannabigerorcinic Acid
CAS :Cannabigerorcinic acid, structurally akin to recognized phytocannabinoids, serves as an analytical reference standard designed for research and forensic purposes.Formule :C18H24O4Couleur et forme :SolidMasse moléculaire :304.386A 77636 hydrochloride
CAS :A 77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM).
Formule :C20H28ClNO3Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :365.89Big Gastrin I (human) TFA
BigGastrinI, human (TFA), is a gastrointestinal hormone comprised of 34 amino acids. It can serve as a potential substance in the study of conditions such as cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurological disorders, or cardiovascular diseases.Formule :C178H252F3Masse moléculaire :2446.96712RAG8 peptide
RAG8 peptide is an antagonist of protease-activated receptor 4 (PAR 4), which inhibits late-stage platelet activation and reduces thrombosis without altering hemostasis or increasing bleeding risk. It is applicable in atherosclerosis research.Formule :C56H98N16O11Masse moléculaire :1170.7601Donitriptan hydrochloride
CAS :Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectivelyFormule :C23H26ClN5O2Degré de pureté :99.8% - 99.86%Couleur et forme :SolidMasse moléculaire :439.94Ref: TM-T21666
2mg40,00€5mg49,00€10mg64,00€25mg135,00€50mg240,00€100mg339,00€200mg439,00€500mgÀ demanderLanepitant
CAS :Lanepitant (LY303870) is a non-peptide neurokinin-1 (NK-1) antagonist with analgesic activity for the prevention of migraine.Formule :C33H45N5O3Degré de pureté :97.71%Couleur et forme :SolidMasse moléculaire :559.74SYD5115
SYD5115 is an orally active TSH-R antagonist.Formule :C22H32F2N4O3Masse moléculaire :438.24425NPFF2-R ligand 1
NPFF2-R ligand 1 (Compound 16a) is an NPFF2-R ligand with Ki values of 228 nM for NPFF1-R and 27 nM for NPFF2-R, and can be utilized in research on central nervous system-related disorders.
Formule :C32H41N3OMasse moléculaire :483.32496PACAP (1-27), human, ovine, rat
CAS :PACAP (1-27) (the N-terminal fragment of PACAP-38) is a novel neuropeptides originally isolated from bovine hypothalamus, also found in humans and rats.Formule :C142H224N40O39SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :3147.66Relaxin H3 (human) TFA
Relaxin H3 (human) (TFA) is a relaxin peptide that exerts antifibrotic effects through the RXFP1 receptor.Formule :C237H374N70O69S6·xC2HF3O2BAY-747
CAS :BAY-747: oral, brain-penetrant sGC stimulator; improves rat memory, cognition, lowers blood pressure, aids Duchenne muscular dystrophy.Formule :C22H26F2N4O2Couleur et forme :SolidMasse moléculaire :416.46Protease-Activated Receptor-1 antagonist 2
CAS :Orally active PAR-1 antagonist with 7 nM IC50; potential for CVD research.Formule :C24H23F2N3O2Couleur et forme :SolidMasse moléculaire :423.46GLP-1R agonist 20
GLP-1R agonist 20 (Compound I-132) is an agonist of the glucagon-like peptide-1 receptor (GLP-1 receptor), with an EC50 value of 0.0162 nM.Formule :C31H30Cl2F2N4O5Masse moléculaire :646.15613palm-PrRP31
palm-PrRP31 is a potent dual agonist for GPR10 (EC50=72 pM) and NPFF-R2. It activates downstream signaling pathways by binding to GPR10 and NPFF-R2 receptors, leading to reduced appetite and increased energy expenditure. palm-PrRP31 can be utilized to investigate its mechanism of action in the nervous system, thereby elucidating the complex biological processes involved in the regulation of appetite and energy expenditure.Formule :C176H282N56O43SMasse moléculaire :3900.1322Antibacterial agent 189
Antibacterialagent 189 (compound 3a) is a potent antibacterial agent with high binding affinity to the target proteins OMPA/exo-1,3-β-glucanase. It demonstrates effective antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis, Candida albicans, and Aspergillus flavus. Additionally, Antibacterialagent 189 exhibits strong binding affinity to the target proteins SMO and SUFU/GLI-1.Formule :C37H28N4OMasse moléculaire :544.22631Azaline B
CAS :Azaline B is an antagonist of the gonadotropin-releasing hormone (GnRH), with an IC50 of 1.37 nM. It is utilized in research related to pathologies associated with sex hormones, ovulation induction, and male contraception.Formule :C80H102ClN23O12Couleur et forme :SolidMasse moléculaire :1613.27GPR183 antagonist-3
GPR183 antagonist-3 (compound 33) is an orally active GPR183 antagonist with an IC50 value of 8.7 μM. It demonstrates significant in vitro anti-migration and anti-inflammatory activity in monocytes and can alleviate pathological symptoms in experimental colitis induced by dextran sulfate sodium.Formule :C21H19BrN4O2SMasse moléculaire :470.04121TRAP-5 amide
CAS :TRAP-5 amide is a peptide agonist for protease-activated receptor 1 (PAR 1) [1].Formule :C30H51N9O6Couleur et forme :SolidMasse moléculaire :633.78Dolcanatide
CAS :Dolcanatide: oral GC-C agonist with laxative, pain-relief, and anti-inflammatory properties for IBD research.Formule :C65H104N18O26S4Couleur et forme :SolidMasse moléculaire :1681.89Palmitoyl tetrapeptide-20 TFA
Palmitoyl tetrapeptide-20 (PTP20) TFA is a biomimetic peptide and acts as an agonist of α-MSH. It protects follicular melanocytes by boosting catalase expression and activating melanogenesis.Formule :C38H70N6O8·xC2HF3O2Peptide C105Y TFA
Peptide C105Y TFA is a cell-penetrating peptide synthesized based on the amino acid sequence of residues 359-374 of α1-antitrypsin. It enhances the gene expression of DNA nanoparticles.Formule :C97H148N20O23S·xC2HF3O2
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