GPCR/G-Protéine
Les inhibiteurs des GPCR/protéines G sont des composés qui ciblent les récepteurs couplés aux protéines G (GPCR) et les protéines G associées, qui jouent un rôle crucial dans la transmission des signaux de l'extérieur vers l'intérieur des cellules. Ces inhibiteurs sont essentiels pour étudier les voies de signalisation médiées par les GPCR, impliquées dans de nombreux processus physiologiques, y compris la perception sensorielle, la réponse immunitaire et la neurotransmission. Les inhibiteurs des GPCR sont également importants dans le développement de médicaments, car de nombreux agents thérapeutiques ciblent ces récepteurs. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de GPCR/protéines G de haute qualité pour soutenir vos recherches en pharmacologie, biologie cellulaire et domaines connexes.
Sous-catégories appartenant à la catégorie "GPCR/G-Protéine"
- récepteur 5-HT(1.025 produits)
- Récepteur d'adénosine(249 produits)
- Récepteur adrénergique(3.018 produits)
- Récepteur de la bombésine(35 produits)
- Récepteur de la bradykinine(61 produits)
- CXCR(158 produits)
- CaSR(34 produits)
- Récepteur cannabinoïde(217 produits)
- Cholécystokinine(1 produits)
- Récepteur de la dopamine(445 produits)
- Récepteur de l'endothéline(86 produits)
- Récepteur GNRH(84 produits)
- GPCR19(33 produits)
- GRK(33 produits)
- GTPase(23 produits)
- Récepteur du glucagon(194 produits)
- Hérisson/Smoothened(49 produits)
- Récepteur de l'histamine(385 produits)
- Récepteur LPA(21 produits)
- Récepteur de la mélatonine(26 produits)
- Récepteur OX(41 produits)
- Récepteur opioïde(327 produits)
- PAFR(14 produits)
- PKA(60 produits)
- Récepteur S1P(18 produits)
- SGLT(31 produits)
- Récepteur Sigma(46 produits)
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5983 produits trouvés pour "GPCR/G-Protéine"
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GLI1-IN-3
GLI1-IN-3 (Compound 11a) is a triterpenoid-like compound that inhibits Hedgehog signaling in cancer cells with GLI1 overexpression. It suppresses the proliferation of non-small cell lung cancer and prostate cancer cell lines with excessive Hh signaling activation. Additionally, GLI1-IN-3 reduces the expression of GLI1 protein and its target genes associated with tumor progression and proliferation in A549 and DU-145 cancer cells.Couleur et forme :Odour SolidACTH (7-38) (human)
CAS :ACTH (7-38) (human) is a fragment (7-38) of the full human adrenocorticotropic hormone (ACTH (1-39)), also referred to as corticotropin inhibitory peptide (CIPFormule :C167H257N47O46Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3659.11Pentagastrin meglumine
CAS :Pentagastrin meglumine is a synthetic pentapeptide that has effects like gastrin when given parenterally.Formule :C44H66N8O14SCouleur et forme :SolidMasse moléculaire :963.11PZ-1922
PZ-1922 (Compound 16), able to cross the blood-brain barrier, is a dual antagonist for 5-HT6R and 5-HT3R with K i values of 17 nM and 0.45 nM, respectively.Degré de pureté :98%Couleur et forme :Odour SolidYM 09538
CAS :YM 09538 is a biochemical.Formule :C18H25ClN2O5SCouleur et forme :SolidMasse moléculaire :416.92(±)14(15)-EpETE
CAS :(±)14(15)-EpETE is an intestinal microbial lipid metabolite that attenuates cisplatin chemotherapy-induced nausea in rats by inhibiting Substance P release.Formule :C20H30O3Couleur et forme :SolidMasse moléculaire :318.45Azirkitug
Azirkitug is a humanized IgG1κ antibody targeting CCR8, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Couleur et forme :Odour LiquidONO-8711
CAS :ONO-8711 is a potent and selective competitive antagonist of EP1 receptor with Kis of 0.6 nM and 1.7 nM for human and mouse EP1, respectively.Formule :C22H30ClNO4SCouleur et forme :SolidMasse moléculaire :440Antipsychotic agent-2
Compound 11: potent antipsychotic, binds 5-HT1A/2A/2C, D2, H1 receptors; K is 56.6-1140 nM, BBB permeable.Formule :C22H26FN5OCouleur et forme :SolidMasse moléculaire :395.47Denrakibart
Denrakibart is a humanized IgG2κ antibody targeting CCL17, with HumanIgG2kappa, Isotype Control serving as the corresponding isotype control.Couleur et forme :Odour LiquidSuccinate/succinate receptor antagonist 1
CAS :Potent succinate receptor antagonist with IC50 of 20 μM; blocks gingival succinate signaling, may treat periodontal disease.
Formule :C17H15N3ODegré de pureté :99.53%Couleur et forme :SoildMasse moléculaire :277.32CCR2 antagonist 1
CAS :CCR2 antagonist 1 is a high-affinity and long-residence-time antagonist of CCR2 (Ki: 2.4 nM).Formule :C28H32BrF3N2OCouleur et forme :SolidMasse moléculaire :549.47Antidepressant agent 4
Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.Formule :C19H38ClN5O2SCouleur et forme :SolidMasse moléculaire :436.06[Leu13]-Motilin
CAS :[Leu13]-Motilin (KW-5139) is an analogue of the gastrointestinal hormone motilin that induces concentration-dependent contractions in rabbit gastrointestinalFormule :C121H190N34O35Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2681.01Poly-D-lysine hydrobromide (MW 1000-5000)
Poly-D-lysine hydrobromide (PDLHB) (MW 1000-5000) is a synthetically produced polymeric substrate widely used in neural cell culture. Additionally, Poly-D-lysine hydrobromide acts as a CaSR agonist peptide.Couleur et forme :Odour SolidPoly-D-lysine hydrobromide (MW 150000-300000)
Poly-D-lysine hydrobromide (MW 150000-300000) enhances neural cell adhesion in culture and acts as a calcium-sensing receptor agonist peptide in research.Couleur et forme :Odour SolidUrocortin II, human TFA
hUcn II, a CRF family member, targets CRF2 receptor, has time-linked stress regulation effects, showing mild motor suppression and delayed anxiolytic action.Formule :C196H340F3N63O56SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4564.3L-770644
CAS :L-770644 is an agonist of B3 adrenergic receptor.Formule :C30H37N7O4SCouleur et forme :SolidMasse moléculaire :591.72ACTH (1-17)
CAS :ACTH (1-17), a potent MC1 receptor agonist with a Ki of 0.21 nM, is a variant of corticotropin from the pituitary gland.Formule :C95H145N29O23SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2093.41Neuropeptide Y (22-36)
CAS :Neuropeptide Y (22-36) is a 15-amino acid fragment of NPY, which is abundant in the mammalian brain and involved in multiple physiological functions.Formule :C85H139N29O21Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1903.19Vapreotide
CAS :Vapreotide is an antagonist of the neurokinin-1 (NK1) receptor (IC50: 330 nM).Formule :C57H70N12O9S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1131.38Antidepressant agent 3
Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.Formule :C17H30ClN5O2SCouleur et forme :SolidMasse moléculaire :403.97PACAP (1-27), human, ovine, rat TFA
PACAP (1-27) TFA is a pacap-38 fragment and PACAP receptor antagonist with IC50s: 3nm (rat PAC1), 2nm (rat VPAC1), 5nm (human VPAC2).Formule :C144H225F3N40O41SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :3261.68MK-0493 HCl
CAS :MK-0493 is a novel, potent, and selective agonist for melanocortin receptor 4 (MC4R).Formule :C30H39Cl2F2N3O2Couleur et forme :SolidMasse moléculaire :582.55Met-RANTES,human,acetate
Met-RANTES (human) acetate is the acetate salt form of Met-RANTES (human). It acts as an antagonist for CCR1 and CCR5 receptors. This compound inhibits the human chemokines MIP-1α and MIP-1β, with respective IC50 values of 5 and 2 nM. Additionally, Met-RANTES (human) acetate reduces bone destruction and alleviates adjuvant-induced arthritis (AIA) in rats.Couleur et forme :Odour SolidUrocortin II, human
Human urocortin (hUcn) II is a new member of the corticotropin-releasing-factor (CRF) family. It selectively binds to the CRF2 receptor.Formule :C194H339N63O54SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4450.28Israpafant
CAS :Israpafant: PAF receptor blocker, IC50 0.84nM, hinders platelet aggregation, eosinophil activation, boosts calcium transit, anti-nephrotoxic.Formule :C28H29ClN4SCouleur et forme :SolidMasse moléculaire :489.07GFB-024
GFB-024 is a humanized antibody targeting CB1, which can be used to study obesity.Couleur et forme :LiquidMasse moléculaire :146.12 kDaK1-70
K1-70 is a humanized antibody targeting TSHR, used in the study of autoimmune diseases and endocrine disorders.Couleur et forme :LiquidMasse moléculaire :143.54 kDaJPC0323
JPC0323 is a dual positive allosteric modulator of the 5-HT2C and 5-HT2A receptors, featuring on-target properties, acceptable plasma exposure, and adequateFormule :C22H43NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :385.58Cafelkibart
Cafelkibart is a chimeric IgG1κ monoclonal antibody targeting CCR8, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Couleur et forme :Odour LiquidSatavaptan
CAS :Satavaptan is a vasopressin V2 receptor antagonist. Satavaptan improves the control of ascites in cirrhosis.Formule :C33H45N3O8SCouleur et forme :SolidMasse moléculaire :643.79Uroguanylin (human)
CAS :Uroguanylin (human) serves as a natural ligand for the Guanylyl Cyclase C (GCC) receptor in metastatic colorectal cancer tumors and exhibits anti-tumor effectsFormule :C64H102N18O26S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1667.86VVZ-149
VVZ-149 is an antagonist of both serotonin receptor 2A (5HT2A) and glycine transporter type 2 (GlyT2), with potential anti-nociceptive activity.Couleur et forme :SolidMaridebart
CAS :Maridebart is a humanized IgG1-kappa monoclonal antibody that targets the GIPR (gastric inhibitory polypeptide receptor) [1].Couleur et forme :LiquidAMTG-DA1
AMTG-DA1 is a ligand for the gastrin-releasing peptide receptor (GRPR), and it can be utilized in cancer research.Formule :C101H149IN22O25Couleur et forme :SolidMasse moléculaire :2197.0109Rhazimine
CAS :Rhazimine is an indole alkaloid. It is a dual inhibitor of arachidonic acid metabolism and platelet activating factor-induced platelet aggregation.Formule :C21H22N2O3Couleur et forme :SolidMasse moléculaire :350.418Phoenixin-14
CAS :Phoenixin-14 (PNX-14), an active endogenous isoform, induces an anxiolytic effect by activating the AHA GnRH system in mice and protects against ischemia/
Formule :C75H110N18O20Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1583.78Anti-TSHR Antibody (M22)
Anti-TSHR Antibody (M22) is a humanized IgG1 monoclonal antibody targeting the thyroid-stimulating hormone receptor (TSHR). This antibody is capable of inhibiting the interaction between TSH and TSHR.Couleur et forme :Odour LiquidCetirizine Impurity C
CAS :Cetirizine Impurity C - a metabolite of hydroxyzine, is a long-acting, oral H1-antihistamine.Formule :C21H25ClN2O3Couleur et forme :SolidMasse moléculaire :388.89Oxyntomodulin
CAS :GLP-1 analog modulates appetite, boosts metabolism, and curbs gastric acid. Increases cAMP, mildly stimulates glucagon receptor.Formule :C192H295N59O60SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4421.86Binospirone
CAS :Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of movement disorders associated with neurologic dysfunction.Formule :C20H26N2O4Degré de pureté :97.57% - 98.96%Couleur et forme :SoildMasse moléculaire :358.43Ref: TM-T71138L
1mg109,00€5mg261,00€10mg374,00€25mg583,00€50mg803,00€100mg1.063,00€200mg1.459,00€1mL*10mM (DMSO)33,00€CB2R agonist 2
CB2R agonist 2 (cis-17-para) is a CB2R agonist [1].Degré de pureté :98%Couleur et forme :Odour SolidSC 31391
CAS :SC 31391 is a PGE1 analog.Formule :C24H32O6Couleur et forme :SolidMasse moléculaire :416.51CHS-114
CHS-114 (SRF-114) is a fully human IgG1 antibody targeting the (CCR8) receptor. It shows potential for research in head and neck squamous cell carcinoma (HNSCC). The isotype control for CHS-114 can be referred to as HumanIgG1kappa, Isotype Control.Couleur et forme :Odour LiquidIsobutyryl-L-carnitine
CAS :Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.Formule :C11H21NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :231.29[Des-His1,Glu9]-Glucagon amide
CAS :Glucagon blocker with pA2 of 7.2; no agonist effect. Boosts insulin; prevents glucagon-driven hyperglycemia in rabbits and diabetic rats.Formule :C148H221N41O47SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :3358.68Sigma-1 receptor antagonist 5
Sigma-1 receptor antagonist 5 (compound 12), a 4-pyridylpiperidine derivative, exhibits analgesic properties through its antagonistic action on sigma receptorsFormule :C26H27N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :397.51S1R agonist 1
CAS :Compound 6b: Selective S1R agonist, K i = 0.93 nM (S1R), 72 nM (S2R); neuroprotective against ROS, NMDA toxicity.Formule :C20H25NOCouleur et forme :SolidMasse moléculaire :295.42Guanylin TFA (mouse,rat)
Guanylin (mouse, rat) TFA is a peptide composed of 15 amino acids and acts as an activator of intestinal guanylate cyclase. This compound is utilized in research related to diarrhea.Formule :C60H90N16O22S4·xC2HF3O2Couleur et forme :SolidMasse moléculaire :1515.71 (free base)TCMCB07
CAS :TCMCB07, a cyclic nonapeptide, serves as an orally active, brain-penetrant antagonist of the melanocortin receptor 4 (MC4R), with significant implications inFormule :C63H87N15O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1230.46PG 106 acetate
PG 106 acetate: Selective hMC3 receptor antagonist, IC50=210 nM; inactive on hMC5 and hMC4, EC50=9900 nM.Formule :C53H73N13O11Degré de pureté :98.24%Couleur et forme :SolidMasse moléculaire :1068.23Conessine hydrobromide
CAS :Conessine hydrobromide is a naturally occurring steroid alkaloid and has been used in traditional herbal medicine as a treatment for amoebic dysentery.Formule :C24H41BrN2Couleur et forme :SolidMasse moléculaire :437.51Invopressin
CAS :Invopressin (Compound 42), a vasopressin V1A receptor partial agonist (EC50: 1.0 nM), is utilized in research related to cirrhosis conditions such as bacterialFormule :C110H161N31O27S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2413.78KwFwLL-NH2
CAS :KwFwLL-NH2 is a hexapeptide that serves as a ligand for the ghrelin receptor (ghrelin receptor). This compound acts as a specific inverse agonist for the ghrelin receptor, exhibiting moderate potency (EC50=45.6 nM).Formule :C49H66N10O6Couleur et forme :SolidMasse moléculaire :891.11(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin
CAS :(d(CH2)5[Tyr(Me)2, Dab5]AVP), a vasopressin V1a receptor-specific antagonist, demonstrates a pA2 value of 6.71 [1].Formule :C52H76N14O11S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1137.38MDL 29913
CAS :NK2 tachykinin receptor selective antagonist.Formule :C40H56N8O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :745Mibenratide TFA
Mibenratide TFA, a small cyclic peptide, functions as an adrenergic β1 receptor antagonist and has potential applications in heart failure research [1].Degré de pureté :98%Couleur et forme :Odour SolidBenzomalvin A
CAS :Benzomalvin A is a filamentous fungal secondary metabolite.Formule :C24H19N3O2Couleur et forme :SolidMasse moléculaire :381.43Femoxetine
CAS :Femoxetine: antidepressant, enhances morphine, inhibits MAO-A/B, boosts mice's exercise capacity.Formule :C20H25NO2Degré de pureté :99.1% - 99.35%Couleur et forme :SolidMasse moléculaire :311.42Spantide II
CAS :Spantide II is an antagonist of tachykinin.Formule :C86H104Cl2N18O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1668.77Bertilimumab
CAS :Bertilimumab (CAT 213; iCo-008), a human monoclonal antibody that targets eotaxin-1 (CCL11), shows promise in the research of allergic disorders [1].Couleur et forme :Liquid(Leu31,Pro34)-Peptide YY (human) (TFA)
"(Leu31,Pro34)-Peptide YY (human) (TFA) is the trifluoroacetic acid (TFA) form of (Leu31,Pro34)-Peptide YY (human), a derivative of Peptide YY that acts as aFormule :C195H296N54O56·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4292.75 (free base)Spns2-IN-1
Spns2-IN-1 is a potent Spns2 inhibitor, effectively impeding Spns2-dependent S1P transport with an IC50 value of 1.4±0.3 μM, crucial for modulating the immuneDegré de pureté :98%Couleur et forme :Odour SolidGalanin (1-16), mouse, porcine, rat TFA
Galanin (1-16) agonizes hippocampal receptors; Kd 3 nM. Active on locus coeruleus neurons in mice, pigs, rats.Formule :C80H117F3N20O23Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1783.915-keto Latanoprost
CAS :Latanoprost, a PG analog for ocular pressure, metabolizes into 15-keto latanoprost, a less potent variant reducing intraocular pressure and pupil size.Formule :C26H38O5Couleur et forme :SolidMasse moléculaire :430.58Bodilisant
CAS :Bodilisant: nanomolar-affinity hH3R ligand, derived from piperidine, with BODIPY fluorophore.Formule :C27H34BF2N3OCouleur et forme :SolidMasse moléculaire :465.4HTL22562
CAS :HTL22562 is a calcitonin gene-related peptide (CGRP) receptor antagonist for acute treatment of migraine.Formule :C40H49N11O5Couleur et forme :SolidMasse moléculaire :763.904B7-33
CAS :B7-33 is a single-chain relaxin analog and a selective agonist for relaxin receptor 1 (RXFP1). It binds to RXFP1 and preferentially activates the pERK pathway in cells expressing RXFP1, rather than cAMP. B7-33 serves as an antifibrotic agent and provides cardioprotective effects.Formule :C131H229N41O36SCouleur et forme :SolidMasse moléculaire :2986.54Thioperamide maleate
CAS :Thioperamide maleate (MR-12842 maleate) is an effective and selective antagonist of H3 receptor (Ki = 4.3 nM) for inhibition of [3H]histamine synthesis (Ki = 31Formule :C19H28N4O4SDegré de pureté :98.48%Couleur et forme :SolidMasse moléculaire :408.52σ1 Receptor ligand 1
σ1 Receptor ligand 1 (compound 5I) is a σ1 receptor ligand with a Ki value of 3.9 nM. It demonstrates a high plasma protein binding rate (89%) and exhibits good metabolic stability in the presence of mouse liver microsomes and NADPH. σ1 Receptor ligand 1 is applicable in neuroscience and cancer research.Formule :C22H28N2O2Couleur et forme :SolidMasse moléculaire :352.47Velmupressin
CAS :Peptidic V2R agonist, c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2, with EC50: 0.07 nM (hV2R), 0.02 nM (rV2R); selective, short-acting.Formule :C42H60ClN11O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :946.58PACAP (6-38), human, ovine, rat
CAS :PACAP (6-38) in humans, sheep, rats: a strong inhibitor of PACAP 38, outperforms PACAP (6-27) in blocking PACAP-27-induced adenylate cyclase.Formule :C182H300N56O45SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4024.74Imnopitant dihydrochloride
CAS :Imnopitant dihydrochloride is a neurokinin NK1 receptor antagonist [1] .Formule :C28H30Cl2F6N4OCouleur et forme :SolidMasse moléculaire :623.46Lys-γ3-MSH(human)
CAS :Pro-opiomelanocortin (POMC) derived peptide that stimulates lipolysisFormule :C128H193N45O39SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :3018.25CCR4 antagonist 3 hydrochloride
CAS :Orally active CCR4 antagonist 3 hydrochloride with potent selectivity, IC50s: 22/50 nM; has antitumor properties.Formule :C24H27Cl2N7O·xHClCouleur et forme :SolidTHX-B
CAS :THX-B, a potent non-peptidic p75 NTR antagonist, aids in researching diabetic kidney disease and neurodegenerative and inflammatory disorders.Formule :C16H24N6O4Couleur et forme :SolidMasse moléculaire :364.4Albiglutide fragment TFA
Albiglutide fragment (GLP-1 (7-36) analog) TFA represents a biologically active segment of Albiglutide, resistant to DPP-4 degradation due to its structure as aFormule :C148H224N40O45·xC2HF3O2Couleur et forme :SolidBIBP3226
CAS :BIBP3226 is a potent and selective antagonist for the Neuropeptide Y receptor Y1 and the neuropeptide FF receptor.Formule :C27H31N5O3Couleur et forme :SolidMasse moléculaire :473.578-iso Prostaglandin E2
CAS :"8-iso PGE2: Isoprostane from arachidonic acid, potent rat renal vasoconstrictor, reduces GFR and renal flow by 80%, no BP effect."Formule :C20H32O5Couleur et forme :SolidMasse moléculaire :352.47GLP-1R agonist 16
CAS :Compound 115a, a GLP-1R agonist, effectively activates the GLP-1 receptor with an EC50 of 0.15 nM [1].Formule :C50H58FN10O6PCouleur et forme :SolidMasse moléculaire :945.03Galanin Receptor Ligand M35
CAS :M35, a galanin(1-13)-bradykinin(2-9) amide, acts as a galanin antagonist in rats and inhibits mouse pancreatic islets.Formule :C107H153N27O26Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2233.63-Deoxyglucosone
CAS :3-Deoxyglucosone(3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with proteinFormule :C6H10O5Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :162.141-(2-Methoxyphenyl)piperazine hydrochloride
CAS :Compound PDK0265, with CAS No. 5464-78-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0265 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C11H16N2OMasse moléculaire :192.25[Deamino-Pen1,Val4,D-Arg8]-vasopressin
CAS :[Deamino-Pen1,Val4,D-Arg8]-vasopressin (AVP-A) is an antagonist of arginine-vasopressin (AVP).Formule :C48H69N13O11S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1068.27BRD9 ligand-6
CAS :BRD9 ligand-6 serves as a ligand for the target protein in PROTAC applications. It is utilized in the synthesis of FHD-609.Formule :C21H21N3O4Couleur et forme :SolidMasse moléculaire :379.41TH023
TH023 is an inhibitor of the TLR4 signaling pathway, specifically targeting the formation of TLR4 homodimers. In HEK-Blue hTLR4 cells, TH023 suppresses the secretion of embryonic alkaline phosphatase with an IC50 of 0.354 μM and inhibits NO expression in RAW264.7 cells, with an IC50 of 1.61 μM. Additionally, TH023 inhibits the activation of NF-κB and reduces the nuclear translocation of NF-κB p65. The compound demonstrates anti-inflammatory effects in a mouse model of LPS-induced acute sepsis and improves lung injury in mice.Formule :C22H21ClF2N4OCouleur et forme :SolidMasse moléculaire :430.88GLP-1R agonist 4
CAS :GLP-1R agonist 4, potentially for diabetes research, is a potent GLP-1R stimulator linked to hypoglycemia.Formule :C32H30ClF2N3O5Couleur et forme :SolidMasse moléculaire :610.05RC-160 [Lys(Boc)]
CAS :RC-160 [Lys(Boc)], an 8-amino acid peptide, functions as a somatostatin analog [1].Formule :C62H78N12O11S2Couleur et forme :SolidMasse moléculaire :1231.49Detomidine carboxylic acid
CAS :Detomidine carboxylic acid, a urine metabolite of detomidine, is a synthetic α2-agonist, animal analgesic, with cardiac, respiratory, and diuretic effects.Formule :C12H12N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :216.24(D-Arg8)-Inotocin
CAS :'(D-Arg8)-Inotocin is a potent, selective, and competitive antagonist of the vasopressin receptor (V 1a R), exhibiting a binding affinity (K i) of 1.3 nM.Formule :C39H68N14O11S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :973.17GHRF, mouse
CAS :GHRF (mouse), a mouse growth hormone-releasing factor, is a 44-amino acid peptide that promotes the synthesis and release of growth hormone [1].Tamuzimod
CAS :Tamuzimod, an effective immunomodulator, exhibits modulatory activity on S1P Receptors with EC50 values below 1 μM [1] [2].Formule :C21H13Cl3F3N5O3Couleur et forme :SolidMasse moléculaire :546.71Ro60-0175
CAS :Ro60-0175 is a selective 5-HT2B and 5-HT2C serotonin receptor agonist, often used as fumarate.Formule :C11H12ClFN2Degré de pureté :97.09%Couleur et forme :SolidMasse moléculaire :226.68Ref: TM-T39161
1mg93,00€5mg205,00€10mg334,00€25mg587,00€50mg802,00€100mg1.108,00€1mL*10mM (DMSO)187,00€(Rac)-FK 480
CAS :(Rac)-FK 480 may be used to study epilepsy or anxiety disorders.Formule :C26H19FN4O2Degré de pureté :97.43%Couleur et forme :SolidMasse moléculaire :438.45PF-232798
CAS :PF-232798 is a second generation oral CCR5 antagonist with potent broad-spectrum anti-HIV-1 activity.Formule :C29H40FN5O2Couleur et forme :SolidMasse moléculaire :509.66Gastrin-Releasing Peptide, human
CAS :Gastrin-releasing peptide, released by vagal fibers, stimulates stomach G cells to secrete gastrin, affecting acid secretion and gut motility.Formule :C130H204N38O31S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2859.38Ribupatide
CAS :Ribupatide is a dual agonist of gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptors and can be utilized in antidiabetic research.Couleur et forme :SolidPAR 4 (1-6)
CAS :PAR 4 (1-6) can be used for relevant research in the life sciences. Its product number is T36293 and CAS number is 225779-44-2.Formule :C28H41N7O9Couleur et forme :SolidMasse moléculaire :619.676EP4 receptor antagonist 3
CAS :EP4 receptor antagonist 3 from patent WO2010019796 A1 targets EP4 for research on pain, arthritis, and cancer.Formule :C26H21F3N2O3SCouleur et forme :SolidMasse moléculaire :498.52Oxmetidine FA
Oxmetidine FA is an orally available specific histamine H2 receptor antagonist with antiulcerogenic properties.Formule :C20H23N5O5SDegré de pureté :97.34%Couleur et forme :SoildMasse moléculaire :445.49DOTA-LM3 TFA
DOTA-LM3 TFA is a somatostatin receptor (SSTR) antagonist with the molecular structure p-Cl-Phe-cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr-NH2.Formule :C71H94ClF3N16O21S2Couleur et forme :SolidMasse moléculaire :1664.18ACT-1016-0707
CAS :ACT-1016-0707 is a selective, insurmountable LPA1 antagonist with antifibrotic and anti-inflammatory activity in lung fibrosis modelsFormule :C19H23ClN4O4SDegré de pureté :99.905%Couleur et forme :SolidMasse moléculaire :438.93Hemokinin 1, human TFA
Hemokinin-1 is a human TFA and selective NK1 agonist; also activates NK2 & NK3 and induces opioid-independent analgesia.Formule :C56H85F3N14O16SCouleur et forme :SolidMasse moléculaire :1299.42PAR-4 Agonist Peptide, amide
CAS :PAR-4 Agonist Peptide, amide (AY-NH2) is an agonist of proteinase-activated receptor-4 (PAR-4).Formule :C34H48N8O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :680.79PG106 TFA
PG106 TFA is a potent hMC3 antagonist (IC50=210 nM), inactive at hMC4 (EC50=9900 nM) and hMC5 receptors.Formule :C53H70F3N13O11Couleur et forme :SolidMasse moléculaire :1122.2GHRF, porcine
CAS :GHRF, porcine, a growth hormone releasing factor (GHRF) peptide (porcine), binds to the growth hormone secretagogue receptor (GHSR), thereby inducing theFormule :C219H365N73O66SCouleur et forme :SolidMasse moléculaire :5108.76α-Helical CRF(9-41) TFA
α-Helical CRF(9-41) TFA acts as a competitive antagonist for the CRF2 receptor, possessing a binding constant (K B) of approximately 100 nM.Formule :C168H275F3N46O55S2Couleur et forme :SolidMasse moléculaire :3940.42Corazonin
CAS :Corazonin, a neuropeptide in insects, regulates caste identity and behavior, mainly in workers/foragers.Formule :C62H83N17O19Couleur et forme :SolidMasse moléculaire :1370.42dCNP
dCNP binds to NPR-B/C receptors (NPR-B/C receptor), initiating the cGMP signaling pathway and regulating vascular function. It exhibits anti-hypoxic effects by downregulating hypoxia-related genes such as HIF1α and HIF2α. Additionally, dCNP inhibits tumor stroma induction, demonstrating antifibrotic properties. It also enhances immune response by upregulating CTL, NK cells, and conventional type 1 dendritic cells in tumors.Formule :C141H248N38O36S3Couleur et forme :SolidMasse moléculaire :3147.91Human growth hormone-releasing factor TFA
Human growth hormone-releasing factor TFA is a hypothalamic peptide that promotes GH secretion by targeting pituitary GHRHR.Formule :C217H359F3N72O68SCouleur et forme :SolidMasse moléculaire :5153.67Ecnoglutide
CAS :Ecnoglutide (XW003) is a glucagon-like peptide 1 (GLP-1) receptor agonist [1] .Formule :C194H304N48O61Couleur et forme :SolidMasse moléculaire :4284.76K-(D-1-Nal)-FwLL-NH2 TFA
K-(D-1-Nal)-FwLL-NH2 TFA: potent ghrelin inverse agonist; Ki=4.9 nM (COS7), 31 nM (HEK293T); blocks Gq/G13 signaling.Formule :C53H68F3N9O8Couleur et forme :SolidMasse moléculaire :1016.16ANQ-11125 TFA
ANQ-11125 TFA is a motilin antagonist with a pKd of 8.24, inhibiting motilide contractions in rabbits.Formule :C88H126F3N19O23Couleur et forme :SolidMasse moléculaire :1875.05Neuropeptide Y (18-36) (porcine)
CAS :"Neuropeptide Y (18-36) (porcine) is a NPY heart receptor blocker, halts I-NPY binding, aids in heart failure research."Formule :C112H174N36O27Couleur et forme :SolidMasse moléculaire :2456.8Sphinganine 1-phosphate
CAS :Sphinganine 1-phosphate has protects kidney and liver through activation of the S1P1 receptor in mice and acts as an agonist for S1P4 in Homo sapien.Formule :C18H40NO5PCouleur et forme :SolidMasse moléculaire :381.49ACTH (1-14) (TFA)
ACTH (1-14) (TFA) is a regulatory fragment of adrenocorticotropin, specifically involved in the control of cortisol and androgen synthesis [1].Formule :C79H110F3N21O22SMasse moléculaire :1794.9Selepressin acetate
Selepressin acetate is a useful organic compound for research related to life sciences and the catalog number is T73654.Formule :C48H77N13O13S2Couleur et forme :SolidMasse moléculaire :1108.33[Ala2] Endothelin-3, human
CAS :[Ala2] Endothelin-3, a linear ET-3 analog with Ala replacing Cys, stimulates endothelial cell migration.Formule :C120H166N26O32S4Couleur et forme :SolidMasse moléculaire :2613.02Dotanoc
CAS :Dotanoc is a ligand to make gallium Ga 68-DOTANOC, which is a gallium Ga 68-radiolabeled analog of somatostatin.Formule :C69H94N14O17S2Couleur et forme :SolidMasse moléculaire :1455.71Gastrin I, rat
CAS :Gastrin I, rat is a peptide hormone that effectively stimulates gastric acid secretion.Formule :C94H128N22O31S2Couleur et forme :SolidMasse moléculaire :2126.3Neuropeptide Y (3-36) (porcine)
CAS :Neuropeptide Y (3-36) (porcine) is a potent, selective agonist at NPY Y2 receptors, increasing feeding in rats.Formule :C176H271N53O54Couleur et forme :SolidMasse moléculaire :3993.36CCK (26-30) (sulfated)
CAS :CCK (26-30) is a digestive and satiety-related peptide fragment inhibiting [125I]CCK-33 binding by 10% at 0.1 mM.Formule :C33H41N7O12S2Couleur et forme :SolidMasse moléculaire :791.85GRPP (human)
CAS :GRPP (human), a 30-amino-acid peptide derived from Gcg, modestly elevates plasma insulin levels while reducing plasma glucagon concentrations.Formule :C136H215N41O58SCouleur et forme :SolidMasse moléculaire :3384.47AY 254
CAS :AY 254: Potent PAR2 agonist, ERK1/2 activation (EC50=2 nM), limits caspase 3/8, aids HT29 cell healing, boosts IL-8.
Formule :C30H49N9O6Couleur et forme :SolidMasse moléculaire :631.779(D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH
CAS :Analog of LHRH, stimulates LH and FSH release, controls reproduction.Formule :C59H84N18O14Couleur et forme :SolidMasse moléculaire :1269.41Peptide YY (PYY) (3-36), porcine TFA
Peptide YY (PYY) (3-36), porcine TFA, functions as a gut hormone that serves as a Y2 receptor agonist, effectively reducing appetite [1].Formule :C176H272N52O54·C2HF3O2Couleur et forme :SolidMasse moléculaire :4094.44PAMP-12 (unmodified) (TFA)
PAMP-12 (unmodified) TFA, an endogenous peptide and potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM), induces hypotension by inhibiting catecholamine secretionFormule :C79H119F3N24O17Couleur et forme :SolidMasse moléculaire :1733.94PG-931 TFA
PG-931 TFA, a potent MC4 receptor agonist (IC50 0.58 nM), excels in selectivity and helps reverse hemorrhagic shock in vivo.Formule :C61H86F3N15O13Couleur et forme :SolidMasse moléculaire :1294.42D[LEU4,LYS8]-VP TFA
D[LEU4,LYS8]-VP TFA: V1b receptor agonist; K_i: 0.16 nM (rat), 0.52 nM (human), 1.38 nM (mouse); weak antidiuretic/vasopressor/oxytocic.Formule :C49H68F3N11O13S2Couleur et forme :SolidMasse moléculaire :1140.25Amylin (8-37) (human)
CAS :Amylin (8-37) (human) is a fragment of human IAPP with a hairpin structure.Formule :C138H215N41O46Couleur et forme :SolidMasse moléculaire :3184.43Adrenocorticotropic Hormone (ACTH) (1-10), human
CAS :ACTH (1-10), human: a weak α-MSH mimic at high doses (100-1000 nM), derived from adrenocorticotropin.Formule :C59H78N16O16SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1299.41Alsactide
CAS :Alsactide, an adrenocorticotropic hormone (ACTH) agonist and a heptadecapeptide analogue, is utilized in the study of the central nervous system [1].Formule :C99H155N29O21SCouleur et forme :SolidMasse moléculaire :2119.53GLP-1(9-36)amide TFA
GLP-1(9-36)amide TFA, a DPP-4 metabolite of GLP-1(7-36) amide, antagonizes human pancreatic GLP-1 receptor.Formule :C142H215F3N36O45Couleur et forme :SolidMasse moléculaire :3203.43Pramlintide TFA
Pramlintide TFA, a polypeptide analogue of human amylin and an antidiabetic agent, exhibits antineoplastic properties in colorectal cancer [1].Formule :C173H268N51F3O55S2Couleur et forme :SolidMasse moléculaire :4063.4[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH
CAS :[D-Glp1,D-Phe2,D-Trp3,6]-LH-RH is a synthetic LHRH analog and a GnRH receptor antagonist.Formule :C67H84N16O13Couleur et forme :SolidMasse moléculaire :1321.48Cenderitide
CAS :Cenderitide fuses CNP with DNP, stimulates pGC-A/B, ups cGMP, curbs aldosterone, and aids GFR, not affecting BP—used in heart failure studies.Formule :C158H263N49O50S3Couleur et forme :SolidMasse moléculaire :3745.27Urocortin III (human)
CAS :Urocortin III, a human peptide, binds CRF-R2, affecting insulin via somatostatin feedback with K i values 13.5-100+ nM.Formule :C185H307N53O50S2Couleur et forme :SolidMasse moléculaire :4137.93α-helical CRF 9-41 acetate
α-helical CRF 9-41 acetate is a competitive antagonist of CRF2 (KB = 100 nM) and a partial agonist of CRF1 (EC50 = 140 nM).
Degré de pureté :96.60%Couleur et forme :SolidMasse moléculaire :#N/ARef: TM-TP2048L
1mg208,00€5mg500,00€10mg672,00€25mg1.017,00€50mg1.359,00€100mg1.853,00€200mg2.498,00€Zalospirone
CAS :Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder.Formule :C24H29N5O2Degré de pureté :98.24% - 99.82%Couleur et forme :SolidMasse moléculaire :419.52LE 300
CAS :LE 300 represents a structurally novel type of antagonists acting preferentially at the dopamine D(1)/D(5)receptors and the serotonin 5-HT(2A)receptor.Formule :C20H22N2Degré de pureté :97.91% - 98.79%Couleur et forme :SolidMasse moléculaire :290.4Ki16198
CAS :Ki16198, a methyl ester derivative of Ki16425, blocks LPA1/3, weak on LPA2; inactive on LPA4/5/6. Ki values: 0.34 μM (LPA1), 0.93 μM (LPA3).Formule :C24H25ClN2O5SDegré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :488.98β-CGRP (mouse)
β-CGRP (mouse), a calcitonin gene-related peptide, induces vasodilation and is applicable in research areas including cardiovascular, pro-inflammatory, migraine, and metabolic studies.Formule :C165H265N49O55S2Couleur et forme :SolidMasse moléculaire :3879.29Adenosine receptor agonist 1
Compound 6m, an A3 adenosine receptor (AR) partial agonist, exhibits a K i value of 6.7 nM as an adenosine receptor agonist.Formule :C12H14ClN5O2SeCouleur et forme :SolidMasse moléculaire :374.68Phoenixin-14 TFA
Phoenixin-14 TFA (PNX-14 TFA) is an endogenous neuropeptide that can modulate GnRH receptor expression and exerts anxiolytic effects.Formule :C75H110N18O20·xC2HF3O2Degré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :1583.78 (free base)Linzagolix choline
CAS :Linzagolix choline is a GnRH antagonist. It can be used to study pain associated with uterine fibroids and endometriosis.Formule :C27H28F3N3O8SDegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :611.59V-0219 hydrochloride
V-0219 hydrochloride: oral GLP-1R PAM for obesity-linked diabetes study.
Formule :C20H26ClF3N4O2Degré de pureté :99.97%Couleur et forme :SoildMasse moléculaire :446.89(+)-OSU 6162
CAS :(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.Formule :C15H23NO2SDegré de pureté :98.19%Couleur et forme :SoildMasse moléculaire :281.41Ref: TM-T60027
1mg73,00€5mg146,00€10mg208,00€25mg319,00€50mg447,00€100mg600,00€200mg808,00€1mL*10mM (DMSO)155,00€Minesapride
CAS :Minesapride: novel 5-HT4 partial agonist, may treat constipation-predominant IBS.
Formule :C21H31ClN4O5Degré de pureté :99.85% - 99.88%Couleur et forme :SolidMasse moléculaire :454.95TRPV1/CB2 agonist 1
TRPV1/CB2 agonist 1 (compound 41) is a dual agonist targeting hTRPV1 and CB2 receptors, with an EC50 value of 26.8 μM for hTRPV1. It is applicable in research related to the nervous system.Couleur et forme :Odour SolidCCK Octapeptide, non-sulfated acetate
CCK Octapeptide, non-sulfated acetate is a synthetic desulfated peptide of cholecystokinin.Formule :C51H66N10O15S2Degré de pureté :98.9700%Couleur et forme :SolidMasse moléculaire :1123.26Kassinin
CAS :Kassinin is a peptide derived from the Kassina frog. It belongs to tachykinin family of neuropeptides.Formule :C59H95N15O18SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1334.54Dulaglutide
CAS :Dulaglutide (LY2189265) is a GLP-1 receptor agonist for studying type 2 diabetes mellitus (T2DM).Couleur et forme :SolidP2Y6R antagonist 1
P2Y6R antagonist 1 (compound 5ab) is a selective, orally active antagonist of P2Y6R, featuring an IC50 value of 19.6 nM. This compound also exhibits anti-inflammatory properties.Couleur et forme :Odour SolidINCB 3284 dimesylate
CAS :INCB 3284 dimesylate: oral CCR2 antagonist, blocks MCP-1/hCCR2 binding (IC50: 3.7 nM), potential in acute liver failure research.Formule :C28H39F3N4O10S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :712.7612(S)-HpEPE
CAS :12(S)-HpEPE, a fatty acid created by 12-lipoxygenase on EPA, has unclear biological activities but may resemble 12(S)-HpETE.Formule :C20H30O4Couleur et forme :SolidMasse moléculaire :334.456FR 113680
CAS :FR 113680 is a tripeptide substance P antagonist with NK1 receptor selectivity.Formule :C35H39N5O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :625.726[Leu31,Pro34]-Neuropeptide Y(human,rat)
CAS :High affinity neuropeptide Y Y1 receptor agonist (Ki = 0.39 nM). Also shows affinity for Y4 and Y5 receptors.Formule :C189H284N54O56SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4241Pellotine
CAS :Pellotine is an alkaloid isolated from Lophophora. It acts as an inverse agonist of the 5-HT7 receptor (5-HT7 receptor), with an EC50 of 291 nM. Pellotine shows strong affinity for the 5-HT1DR and 5-HT6R, with Ki values of 117 nM and 170 nM, respectively. Additionally, Pellotine reduces intracellular cAMP levels, thereby decreasing neuronal excitability and neurotransmitter release.Formule :C13H19NO3Couleur et forme :SolidMasse moléculaire :237.295Mini Gastrin I, human
CAS :Mini Gastrin I, human, is a truncated form of the human gastrin peptide, encompassing amino acids 5-17 of the original sequence.Formule :C74H99N15O26SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1646.73GRK-IN-1
CAS :4-Amino-5-(bromomethyl)-2-methylpyrimidine used in vitamin B1 analogs and esters synthesis.
Formule :C6H10Br3N3Couleur et forme :SolidMasse moléculaire :363.879Hydroxybupropion
CAS :Hydroxybupropion is the major active metabolite of Bupropion and an antagonist of nACh receptor. Hydroxybupropion inhibits norepinephrine uptake (IC50 = 1.7 μM).Formule :C13H18ClNO2Degré de pureté :99.73%Couleur et forme :Off-White SolidMasse moléculaire :255.74Ref: TM-T11588
1mg89,00€5mg204,00€10mg331,00€25mg545,00€50mg777,00€100mg1.063,00€1mL*10mM (DMSO)232,00€Clozapine N-oxide dihydrochloride
CAS :Clozapine N-oxide dihydrochloride is a derivative of Clozapine and an agonist of DREADDs.Formule :C18H21Cl3N4ODegré de pureté :98.11%Couleur et forme :SolidMasse moléculaire :415.7420-hydroxy Prostaglandin F2α
CAS :20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α.
Formule :C20H34O6Couleur et forme :SolidMasse moléculaire :370.486LSN3160440
CAS :LSN3160440 is a GLP-1R allosteric modulator and PPI stabilizer aiding inactive GLP-1 attachment.Formule :C27H27Cl2N3OCouleur et forme :SolidMasse moléculaire :480.43TGR5 agonist 4
TGR5 agonist 4 (compound 19), a derivative of cholic acid, selectively activates the TGR5 receptor with an effective concentration (EC50) of 4 μM [1].Formule :C24H38F2O5Couleur et forme :SolidMasse moléculaire :444.55tetranor-PGJM
CAS :Tetranor-PGJM is a metabolite of prostaglandin D2 and is associated with the anti-inflammatory effects of curcumin.
Formule :C16H22O6Couleur et forme :SolidMasse moléculaire :310.346Propranolol hydrochloride
CAS :Propranolol hydrochloride is a widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverseFormule :C16H22ClNO2Degré de pureté :99.94% - >99.99%Couleur et forme :White Or Almost White Powder White PowderMasse moléculaire :295.80Cholecystokinin (27-32)-amide
CAS :Cholecystokinin (27-32)-amide is a CCK receptor antagonist.Formule :C36H48N8O12S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :881.01TT-OAD2 free base
CAS :TT-OAD2 free base, a non-peptide GLP-1 receptor agonist, can treat diabetes; has an EC50 of 5 nM.Formule :C50H47Cl2N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :856.837-Hydroxy-PIPAT maleate
CAS :7-Hydroxy-PIPAT maleate is a D3R agonist.Formule :C16H22INOCouleur et forme :SolidMasse moléculaire :371.262tetranor-PGDM
CAS :PGD2, made by H-PGDS in mast cells and lipocalin-PGD-synthase in the brain, aids sleep, cools the body, and inhibits platelet aggregation.Formule :C16H24O7Couleur et forme :SolidMasse moléculaire :328.361MM 07
CAS :Biased agonist for apelin/G protein pathway, enhances eNOS and cell growth, reduces apoptosis, improves heart function, and dilates vessels.Formule :C67H106N22O14S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1539.9Terazosin dimer impurity dihydrochloride
CAS :Terazosin dimer impurity dihydrochloride is a chemical byproduct of the α1-antagonist Terazosin, derived from quinazoline.Formule :C24H30Cl2N8O4Couleur et forme :SolidMasse moléculaire :565.46Galanin (1-15) (porcine, rat)
CAS :N-terminal galanin fragment used to mediate central cardiovascular effectsFormule :C72H105N19O20Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1556.72RF9
CAS :RF9 is an effective and selective antagonist of the Neuropeptide FF receptor (Kis: 58±5 and 75±9 nM for hNPFF1R and hNPFF2R, respectively).Formule :C26H38N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :482.62FR167344 free base
CAS :FR167344 free base: oral, nonpeptide B2 bradykinin receptor antagonist, high-affinity (IC50: 65 nM), no B1 affinity.Formule :C30H28BrCl2N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :673.3815(S)-15-methyl Prostaglandin F2α methyl ester
CAS :15(S)-15-methyl Prostaglandin F2α methyl ester can be used in related research in the field of life sciences.Formule :C22H38O5Couleur et forme :SolidMasse moléculaire :382.53Flunarizine
CAS :Flunarizine is an orally administered peripheral vasodilator, a dual blocker of voltage-gated Na+/Ca2+ channels and a D2 dopamine receptor antagonist.Formule :C26H26F2N2Degré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :404.50Amylin (IAPP), feline
Amylin (IAPP), feline is the peptide subunit of amyloid found in pancreatic islets of type 2 diabetic patients and in insulinomas.Formule :C165H270N52O54S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3910.45A6770
CAS :A6770 inhibits S1P lyase, causing [3H]dhS1P build-up in IT-79MTNC3 cells (EC50 <0.01 μM); less effective with vitamin B6 (EC50 <100 μM).Formule :C6H8N2O2Couleur et forme :SolidMasse moléculaire :140.142(±)5(6)-EET
CAS :5(6)-EET is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.Formule :C20H32O3Couleur et forme :SolidMasse moléculaire :320.473Dipentylone hydrochloride
CAS :Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.Formule :C14H20ClNO3Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :285.77Amylin (8-37), rat
CAS :Amylin (8-37), rat, an analog of IAPP, blocks insulin's effects on muscle glucose uptake and glycogen storage.Formule :C140H227N43O43Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3200.61{Val1}-Exendin-3/4
{Val1}- exendin-3/4 is the first n-terminal 1-28 residue of exendin-4 peptide.Formule :NADegré de pureté :98%Couleur et forme :SolidMasse moléculaire :3241.7HAEGTFTSD
CAS :HAEGTFTSD is GLP-1's initial segment; GLP-1 (7-36) amide, tied to food intake, stems from preproglucagon in L-cells.Formule :C40H57N11O17Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :963.94Prostaglandin H1
CAS :Prostaglandin H1 is the cyclooxygenase metabolite of DGLA, a CRTh2 agonist and a precursor of a family of 1 anti-inflammatory prostaglandins.Formule :C20H34O5Couleur et forme :SolidMasse moléculaire :354.487Apelin-36(rat, mouse)
CAS :Endogenous APJ agonist from adipocytes; binds APJ tightly, inhibits cAMP, regulates heart function and fluid balance, blocks some HIV strains.Formule :C185H304N68O43SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4200.93NSC380324
NSC380324 is a P2Y12 receptor antagonist with antiplatelet properties, which can be employed in research on atherosclerotic cardiovascular diseases.Formule :C31H24N4O4Couleur et forme :SolidMasse moléculaire :516.555-HT1AR/5-HT6R ligand-1
5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.Formule :C25H29ClN4O2SCouleur et forme :SolidMasse moléculaire :485.04[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P
CAS :Broad-spectrum inverse agonist; potent at ghrelin receptor (EC50=5.2 nM); blocks other neuropeptide receptors; induces apoptosis; inhibits tumor growth.Formule :C79H109N19O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1516.85AR-C126313
CAS :AR-C126313 is a thiouracil derivative.
Formule :C28H23N7O3SCouleur et forme :SolidMasse moléculaire :537.59MAO-B-IN-3
MAO-B-IN-3 is a reversible, selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and demonstrates affinity for the 5-HT6 receptor with a KiFormule :C24H25N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.47DSP-1053
CAS :Dsp-1053 is a powerful SERT (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonizing activity.Formule :C26H32BrNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.44Preclamol hydrochloride
CAS :Preclamol hydrochloride: selective dopamine agonist with research potential in schizophrenia.Formule :C14H22ClNOCouleur et forme :SolidMasse moléculaire :255.78Haloperidol D4
CAS :Haloperidol D4 is deuterium-labeled haloperidol.Formule :C21H23ClFNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :379.89[Phe8Ψ(CH-NH)-Arg9]-Bradykinin
CAS :Selective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage.Formule :C50H75N15O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1046.23MrgprX2 antagonist-2
CAS :MrgprX2 antagonist-2, from patent WO2021092262A1 E163, is potent for skin inflammation studies.Formule :C17H16F5N3O3Couleur et forme :SolidMasse moléculaire :405.325Hemopressin (human, mouse)
CAS :Endogenous peptide, inhibits ep24.15/24.16/ACE with Ki of 27.76/3.43/1.87 μM. Lowers blood pressure, CB1 inverse agonist, reduces pain in vivo.Formule :C50H79N13O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1054.26α1A-AR Degrader 9c
CAS :α1A-AR Degrader 9c is a potent, selective, and reversible PROTAC degrader targeting the α1A adrenergic receptor (α1A-AR) with a DC50 of 2.86 μM.Formule :C38H43N11O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :829.82
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